dexmethylphenidate has been researched along with cocaine in 3 studies
| Studies (dexmethylphenidate) | Trials (dexmethylphenidate) | Recent Studies (post-2010) (dexmethylphenidate) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 10 | 0 | 4 | 32,461 | 1,096 | 9,400 |
| Protein | Taxonomy | dexmethylphenidate (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Collard, DM; Deutsch, HM; Javanmard, S; Kuhar, MJ; Schweri, MM | 1 |
| Mazzolari, A; Pedretti, A; Testa, B; Vistoli, G | 1 |
| Subbaiah, MAM | 1 |
1 review(s) available for dexmethylphenidate and cocaine
| Article | Year |
|---|---|
Triple Reuptake Inhibitors as Potential Therapeutics for Depression and Other Disorders: Design Paradigm and Developmental Challenges.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Drug Design; Humans; Selective Serotonin Reuptake Inhibitors | 2018 |
2 other study(ies) available for dexmethylphenidate and cocaine
| Article | Year |
|---|---|
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-substituted-6-amino-5-phenylbicyclo[2.2.2]octanes.
Topics: Animals; Benzoates; Binding, Competitive; Brain; Bridged Bicyclo Compounds; Carrier Proteins; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Symporters | 1999 |
In silico prediction of human carboxylesterase-1 (hCES1) metabolism combining docking analyses and MD simulations.
Topics: Carboxylic Ester Hydrolases; Catalytic Domain; Computer Simulation; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Substrate Specificity | 2010 |