dexmedetomidine has been researched along with propofol in 632 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 93 (14.72) | 29.6817 |
| 2010's | 359 (56.80) | 24.3611 |
| 2020's | 180 (28.48) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cohen, T; Dutta, S; Jones, RM; Karol, MD; Mant, T | 1 |
| Cloote, AH; Peden, CJ; Prys-Roberts, C; Stratford, N | 1 |
| Kuusela, E; Mykkänen, K; Raekallio, M; Ropponen, H; Vainio, O; Väisänen, M | 1 |
| Bryant, A; Grounds, RM; Hall, GM; Venn, RM | 1 |
| Bekker, A; Beric, A; Bloom, M | 1 |
| Angelini, G; Coursin, DB; Ketzler, JT | 1 |
| Grounds, RM; Venn, RM | 1 |
| Genähr, A; Grosse, J; Konertz, W; Kox, WJ; Moshirzadeh, M; Sidiropoulos, A; Spies, CD; Triltsch, AE; von Homeyer, P; Welte, M | 1 |
| Arain, SR; Ebert, TJ | 1 |
| Hietanen, H; Huttula, J; Kuusela, E; Raekallio, M; Vainio, O | 1 |
| Huju, V; Huttunen, P; Kuusela, E; Leppäluoto, J; Raekallio, M; Short, CE; Ström, S; Vainio, O; Valtonen, A | 1 |
| Barbudo-Selmi, GR; Figueiredo, JP; Lins, BT; Mendes, GM; Selmi, AL | 1 |
| England, M; Herr, DL; Sum-Ping, ST | 1 |
| Feshchenko, VA; Pryor, KO; Reinsel, RA; Veselis, RA | 1 |
| Kulkarni, A; Price, G; Saxena, M; Skowronski, G | 1 |
| Feshchenko, VA; Johnson, R; Reinsel, RA; Veselis, RA | 1 |
| Ramadhyani, U; Shukry, M | 1 |
| Karamanlioglu, B; Kaya, G; Memis, D; Turan, A | 1 |
| Callas, PW; Corbett, SM; Greene, CM; Healey, MA; Leavitt, BJ; Neale, BW; Rebuck, JA | 1 |
| Carlon, GC; Combs, AH | 1 |
| Leung, S; Zapantis, A | 1 |
| Rosen, DA | 1 |
| Almeida, AN; Marino, R; Murata, KN; Sasaki, S; Tavares, C; Tibano, A | 1 |
| Everett, LL; Ojemann, JG; Saneto, RP; Shurtleff, HA; van Rooyen, IF; Warner, MH | 1 |
| Fukuda, K; Iida, H; Matsuura, S; Shirakami, G; Tanimoto, K | 1 |
| Aguilera, E; Benítez, A; Domínguez, JM; Gómez-Villamandos, RJ; Granados, MM; López, I; Palacios, C; Ruiz, I; Santisteban, JM | 1 |
| Dasta, JF; Jacobi, J; McLaughlin, TP; Sesti, AM | 1 |
| Deogaonkar, A; Deogaonkar, M; Ebrahim, Z; Lee, JY; Schubert, A | 1 |
| Ersoy, OM; Koroglu, A; Sagir, O; Teksan, H; Toprak, HI; Yucel, A | 1 |
| Daume, JT; Rosen, DA | 1 |
| Dökmeci, D; Karamanlioğlu, B; Memiş, D; Turan, A; Türe, M | 1 |
| Dinç, G; Gazi, H; Keleş, GT; Kurutepe, S; Tok, D | 1 |
| Kataoka, Y; Mochizuki-Oda, N; Nakao, S; Sakamoto, S; Shingu, K; Takamori, Y; Tamura, Y; Yamada, H; Yamada, M | 1 |
| Akin, A; Boyaci, A; Esmaoglu, A; Guler, G; Tosun, Z | 1 |
| Aoki, M; Baba, H; Nishimura, Y; Okawa, Y | 1 |
| Holmes, MD; Lam, AM; Lee, L; Ojemann, JG; Rozet, I; Souter, KJ; Souter, MJ | 1 |
| Felix, DE; Lagueruela, RG; Madril, DR; Munro, HM; Nykanen, DG; Tirotta, CF; Zahn, EM | 1 |
| Altunkaya, H; Ayoğlu, H; Cukdar, G; Ozer, Y; Ozkoçak, I; Yapakçi, O | 1 |
| Forrest, LK; Kiser, TH; MacLaren, R | 1 |
| Barbosa, NV; Bulow, NM; Rocha, JB | 1 |
| Booij, LH; Frost, EA | 1 |
| Leitch, J; Macpherson, A | 1 |
| Heard, CM; Johnson, K; Joshi, P | 1 |
| Ando, S; Fukuyama, H; Maeda, M; Suzuki, T | 1 |
| Ahonen, H; Berg, L; Laranne, J; Lindgren, L; Nunes, S; Parviainen, I; Raittinen, LP; Ruokonen, E; Tenhunen, J | 1 |
| Begec, Z; Demirbilek, S; Erdil, F; Ersoy, MO; Onal, D; Toprak, HI | 1 |
| Hammer, GB; Ramamurthi, RJ; Seybold, JL | 1 |
| Altemyatt, S; Bakhamees, HS; El-Halafawy, YM; El-Kerdawy, HM; Gouda, NM | 1 |
| Boulis, NM; Cata, JP; Ebrahim, Z; Farag, E; John Doyle, D; Khatib, R; Rezai, A; Schurigyn, T | 1 |
| Ayan, S; Gokce, G; Gultekin, Y; Gursoy, S; Kaygusuz, K; Mimaroglu, C | 1 |
| Hinohara, H; Kadoi, Y; Kawauchi, C; Kunimoto, F; Saito, S | 1 |
| Aspegrén, J; Hellebrekers, LJ; Lin, GY; McKusick, BC; Murrell, JC; Robben, JH | 1 |
| Easley, RB; Tobias, JD | 1 |
| Matsumoto, K; Miki, S; Yanagita, W | 1 |
| Borowics, SM; Breyer, HP; Caumo, W; Fortis, EA; Hidalgo, MP; Maguilnik, I; Muller, S; Soares, G; Stefani, LC | 1 |
| Aherne, A; Anschel, DJ; Carrion, W; Hoegerl, C; Nori, P; Seidman, PA; Soto, RG | 1 |
| Martin, T; Qasim, M; Sangari, T; Shah, S | 1 |
| Canbay, O; Celebi, N; Karagoz, AH; Ozgen, S; Uzümcügil, F | 1 |
| Kalarickal, P; Shukry, M | 1 |
| Fornal, CA; Herrera, S; Jacobs, BL; Tung, A | 1 |
| Kaneko, T | 1 |
| Bratty, JR; Jakob, SM; Kaukonen, M; Nunes, S; Parviainen, I; Ruokonen, E; Sarapohja, T; Shepherd, ST; Takala, J | 1 |
| Pambianco, DJ | 1 |
| Burrows, F; Heard, C; Houck, J; Johnson, K; Joshi, P; Lerman, J | 1 |
| Kida, K; Masaki, E; Ohtani, N; Shoji, K; Yasui, Y | 1 |
| Morton, NS | 1 |
| Anderson, J; Hoernschemeyer, DG; Ngwenyama, NE; Tobias, JD | 1 |
| Johnson, R; Li, Y; Mehta, M; Pryor, KO; Reinsel, RA; Veselis, RA | 1 |
| Chen, MI; Drover, DR; Golianu, B; Hammer, GB; Sam, WJ | 1 |
| Bulut, M; Ganidagli, S; Koruk, S; Mizrak, A; Oner, U | 1 |
| Kobayashi, K; Nakazato, K; Sakamoto, A; Takemori, K; Yoshida, Y | 2 |
| Ali, A; Altan, A; Turgut, N; Turkmen, A | 1 |
| Altun, A; Aydin, C; Bagcivan, I; Gursoy, S; Koyuncu, A; Topcu, O | 1 |
| Fujiwara, H; Hemasilpin, N; König, MW; Lee, KH; Mahmoud, MA; Rose, DF | 1 |
| Iwasaki, H; Kunisawa, T; Mitamura, S; Nagashima, M; Nagata, O; Suzuki, A; Takahata, O; Ueno, M | 1 |
| Chang, C; Fujino, Y; Ma, L; Mashimo, T; Uchiyama, A | 1 |
| Gelfand, HJ; Groblewski, JC; Quezado, ZM; Shah, RK | 1 |
| Donnelly, LF; Gunter, J; Mahmoud, M; Nick, TG; Sadhasivam, S; Wang, Y | 1 |
| Galante, D | 1 |
| Mani, V; Morton, NS | 1 |
| Hidaka, S; Kajiyama, S; Kubo, T; Nakagawa, I; Nao, Y; Okada, H | 1 |
| Diaz, LK; Jones, L | 1 |
| Himeno, K; Oda, H; Okawa, K; Shibutani, T; Shikanai, K; Taniyama, K | 1 |
| Bass, F; Campbell, M; Chen, J; Grant, P; Hammond, N; Shehabi, Y; Wolfenden, H | 1 |
| Memis, D; Sut, N; Tasdogan, M; Yuksel, M | 1 |
| Short, J | 1 |
| Aal-Shaya, WA; Al-Faridi, K; Halawani, MM; Taha, WS; Tawfeeq, NA | 1 |
| Govinda, R; Kasuya, Y; Mascha, EJ; Rauch, S; Sessler, DI; Turan, A | 1 |
| Kargi, M; Memiş, D; Sut, N | 1 |
| Barletta, JF; Heiser, JC; McAllen, KJ; Miedema, SL; Wiseman, D | 1 |
| Hanling, S; Mecklenburg, B; Wallace, S | 1 |
| Ichinohe, T; Kaneko, Y; Okawa, K | 1 |
| Mason, KP | 1 |
| Akça, O; Dalton, JE; Govinda, R; Kasuya, Y; Rauch, S; Sessler, DI; Turan, A; Wo, J | 1 |
| Iwasaki, H; Kanda, H; Kunisawa, T; Kurosawa, A; Nagashima, M; Suzuki, A; Takahata, O | 1 |
| Chen, TI; Chu, KS; Lu, DV; Lu, IC; Tsai, CJ; Wang, HM | 1 |
| Li, HL; She, SZ; Yan, Y; Zhu, SM | 1 |
| Arnold, HM; Hollands, JM; Mice, ST; Skrupky, LP | 1 |
| Hayashi, D; Hiroshi, I; Kunisawa, T; Kurosawa, A; Nagashima, M; Takahata, O | 1 |
| Baspinar, O; Ilhan, O; Kaya Ugur, B; Koruk, S; Mizrak, A; Oner, U | 1 |
| Ayoğlu, H; Baydilek, Y; Erdoğan, G; Hanci, V; Okyay, RD; Turan, IO; Yurtlu, BS | 1 |
| Doi, M; Kurita, T; Mimuro, S; Sano, H; Sato, S; Yu, S | 1 |
| Goepfert, MS; Schulte-Uentrop, L | 1 |
| Sammons, HM; Starkey, E | 1 |
| Ali, AR; El Ghoneimy, MN | 1 |
| Bottum, KM; Karmarkar, SW; Tischkau, SA | 1 |
| Georgiadis, S; Karjalainen, PA; Kaskinoro, K; Laitio, T; Lipponen, JA; Scheinin, H; Tarvainen, MP | 2 |
| Anger, KE; Baroletti, SA; Fanikos, J; Labreche, MJ; Szumita, PM | 1 |
| Komatsu, H; Nishioka, T; Noguchi, H; Sakaki, T; Umegaki, O; Yokota, H; Yokoyama, K | 1 |
| Badjatia, N; Carpenter, AM; Choi, HA; Claassen, J; Fernandez, L; Gilmore, E; Ko, SB; Lee, K; Lesch, C; Malhotra, R; Mayer, SA; Presciutti, M; Schmidt, JM | 1 |
| Allegaert, K; Thewissen, L | 1 |
| Fujinaga, Y; Kashiwa, A; Kojima, Y; Matsuyama, K; Shimamoto, F; Takimoto, K; Toyonaga, T; Ueda, T; Yamauchi, H; Yoshikawa, T | 1 |
| Baughman, VL; Mueller, MF; Paisansathan, C | 1 |
| Bracco, D; Donatelli, F | 1 |
| Devabhakthuni, S; Kufera, JA; Pajoumand, M; Stein, DM; Watson, K; Williams, C | 1 |
| Arabshahi, A; Barnes, S; Frölich, MA; Katholi, C; Prasain, J | 1 |
| Cravero, JP; Havidich, JE | 1 |
| Aantaa, R; Jääskeläinen, S; Kaisti, K; Kaskinoro, K; Långsjö, J; Maksimow, A; Särkelä, M; Scheinin, H | 1 |
| Slovis, TL | 1 |
| Hayashi, D; Iwasaki, H; Kunisawa, T; Kurosawa, A; Nagashima, M; Sasakawa, T; Suzuki, A; Takahata, O; Ueno, M | 1 |
| Jones, WA; Kincaid, EH; Kon, ND; Reichert, MG; Royster, RL; Slaughter, TF | 1 |
| Aantaa, R; Jylhänkangas, L; Kaskinoro, K; Móró, L; Noreika, V; Revonsuo, A; Scheinin, H; Valli, K | 1 |
| Mashour, GA | 1 |
| Fukusaki, M; Higashijima, U; Ichinomiya, T; Miura, K; Sumikawa, K; Tanise, T; Terao, Y | 1 |
| Do, SH; Kim, CS; Lee, EH; Lee, JH; Lee, SW; Ryu, JH | 1 |
| Ganzberg, S; Kawaai, H; Nakaike, Y; Tomita, S; Yamazaki, S | 1 |
| Liu, HL; Zhang, Y; Zheng, GL | 1 |
| Martin, DD; McKusick, BC; McSweeney, PM; Ramsey, DS | 1 |
| Akin, A; Aksu, R; Altuntaş, R; Baykan, A; Bicer, C; Boyaci, A; Esmaoğlu, A; Ülgey, A | 1 |
| Adachi, YU; Kawamata, M; Kimura-Kuroiwa, K; Matsuda, N; Obata, Y; Sato, S | 1 |
| Bratty, JR; Garratt, C; Grounds, RM; Jakob, SM; Pocock, SJ; Ruokonen, E; Sarapohja, T; Takala, J | 1 |
| Wunsch, H | 1 |
| Anitescu, M; Patil, SK | 1 |
| Fang, XM; Hou, TN; Ma, XX | 1 |
| Ichinohe, T; Matsuura, N; Sazuka, S | 1 |
| Liao, X; Xue, FS; Yuan, YJ | 1 |
| Aydogan, MS; Durmus, M; Erdogan, MA; Kurt, A; Parlakpinar, H; Ucar, M; Yucel, A | 1 |
| Babu, R; Bekker, A; Didehvar, S; Haile, M; Kline, R; Martiniuk, F; Urban, M | 1 |
| Akça, O; Dalton, JE; Kasuya, Y; Rauch, S; Sessler, DI; Turan, A | 1 |
| Cang, J; Ge, S; Wang, T; Xiong, W; Xue, Z; Zhou, P | 1 |
| Liu, C; Ruan, X; She, S; Xu, L; Zhang, Y | 1 |
| Beccaglia, M; Bronzo, V; Comazzi, S; Fonda, D; Gallo, M; Gelain, ME; Ravasio, G; Zonca, A | 1 |
| Boku, A; Hanamoto, H; Kudo, C; Morimoto, Y; Niwa, H; Sugimura, M; Toyama, M | 1 |
| Graffagnino, C; James, ML; Olson, DM | 1 |
| Barba-Alvarez, F; De La Mora-González, JF; Espinel Bermúdez, MC; González-Ortiz, M; Llamas-Moreno, JF; Llontop-Pisfil, Ede L; Martínez-Abundis, E; Mora-Martínez, JM; Robles-Cervantes, JA | 1 |
| Baysal, E; Bozgeyik, S; Ganidagli, S; Gul, R; Mizrak, A; Oner, U; Sanli, M | 1 |
| Halttunen, J; Kylänpää, L; Lindström, O; Mazanikov, M; Mustonen, H; Pöyhiä, R; Udd, M | 1 |
| Posner, LP; Suter, SE; Willcox, JL | 1 |
| Hakozaki, T; Imaizumi, T; Isosu, T; Murakawa, M; Nemoto, C; Obara, S | 1 |
| Cohen, MB; Stewart, JT | 1 |
| Chen, Z; Hang, LH; Shao, DH | 1 |
| Devlin, JW; Manjourides, J; Papadopoulos, S; Torbic, H | 1 |
| Apinyachon, W; Ittichaikulthol, W; Jitaree, A; Moontripakdi, O; Prachanpanich, N | 1 |
| Giovannitti, JA | 1 |
| Ahmed, S; Murugan, R | 1 |
| Bian, GY; Hao, J; He, Y; Liu, J; Liu, T; Luo, JS; Weng, Q; Yang, MH | 1 |
| Aydogan, MS; Begec, Z; Colak, YZ; Durmus, M; Yücel, A | 1 |
| Bailey, M; Bass, F; Bellomo, R; Howe, B; McArthur, C; Murray, L; Reade, MC; Seppelt, IM; Shehabi, Y; Webb, S; Weisbrodt, L | 1 |
| Macfarlane, P; Raszplewicz, J; West, E | 1 |
| Lai, Y; Li, Y; Liu, Y; Peng, X; Wang, H; Zou, P | 1 |
| Akarsu Ayazoğlu, T; Akbulut, S; Bolat, C; Duman, U; Polat, E; Yasar, NF; Yol, S | 1 |
| Chen, SQ; Liu, KX; Wen, SH; Xia, ZQ; Xie, CB; Yao, X | 1 |
| Guo, F; Huang, Y; Qiu, H; Teboul, JL; Yang, Y; Yu, T | 1 |
| Curtis, JA; Hollinger, MK; Jain, HB | 1 |
| Akin, A; Aksu, R; Baykan, A; Bayram, A; Bicer, C; Boyaci, A; Güneş, I; Narin, N; Ülgey, A | 1 |
| Ayoglu, H; Bollucuoglu, K; Hanci, V; Okyay, D; Turan, IO; Yurtlu, S | 1 |
| Donnelly, LF; Fleck, R; Gunter, J; Jung, D; Mahmoud, M; McAuliffe, J; Patio, M; Salisbury, S | 1 |
| Moens, YP; Pavlidou, K; Raptopoulos, D; Savvas, I; Vasilakos, D | 1 |
| Gill, RS; Goodwin, HE; Lewin, JJ; Mirski, MA; Murakami, PN; Thompson, CB | 1 |
| Cavarocchi, N; Li, J; McDaniel, CM; Pizzi, LT; Thoma, BN; Wordell, CJ | 1 |
| Jin, T; Shen, SL; Wang, WY; Zhang, J; Zhang, Q; Zheng, JY; Zhu, J | 1 |
| Huang, Y; Jiang, H; Wang, Y; Zhu, Y | 1 |
| Bergman, JJ; Eberl, S; Hollmann, MW; Preckel, B | 1 |
| Chen, J; Chen, ZF; Huang, Y; Jiang, H; Zhou, JQ | 1 |
| Burton, JH; Fesmire, FM; Gerardo, CJ; Godwin, SA; Hatten, BW; Mace, SE; Silvers, SM | 1 |
| Cao, JP; He, Q; He, XY; Shi, XY | 1 |
| Kang, YR; Kim, J; Kim, SY; Koo, BN; Lee, JH | 1 |
| Goldfarb, AA; Koppman, J; Marema, RT; Ziemann-Gimmel, P | 1 |
| Chen, K; Shen, X | 1 |
| Doepker, BA; Elijovich, L; Erdman, MJ; Gerlach, AT; Jones, GM; Phillips, GS | 1 |
| Augé, M; Bonnet, F; Chazot, T; Dardelle, D; Fischler, M; Laloë, PA; Le Guen, M; Liu, N; Sessler, DI; Tounou, F; Tuil, O | 1 |
| Dong, C; Lu, Y; Yu, J; Zhang, Y | 1 |
| Hossain, M; Kurth, D; Mahmoud, M; Schmitt, M; Wu, J | 1 |
| Bahrani, H; Jafari, A; Jalessi, M; Mirkheshti, A; Mohajerani, SA; Mottaghi, K; Safari, F; Salimi, A; Sharifi, G | 1 |
| Bainbridge, D; Jolly, SS; Lavi, R; Lavi, S; Manji, F; Randhawa, V | 1 |
| Kim, JY; Kwak, HJ; Min, SK; Park, KH; Yoo, JY | 1 |
| Duke-Novakovski, T; Palacios-Jimenez, C; Rymes, L; Sanchez-Teran, AF; Wetzel, T | 1 |
| Bioc, JJ; Cucchi, J; Dasta, JF; Devlin, JW; Edwards, RA; Fraser, GL; Magee, C | 1 |
| Erstad, BL; Patanwala, AE | 1 |
| Chen, YF; Chen, Z; Hang, LH; Shao, DH; Wang, H; Wu, X | 1 |
| Altawalbeh, S; Anthes, A; Benedict, N; Felbinger, M; Kane-Gill, S; Ridenour, T | 1 |
| Li, RP; Liu, GP; Xue, FS | 1 |
| Araújo, MN; Cavalcanti, V; Fernandes, FC; Heil, LB; Morales, MM; Pelosi, P; Rocco, PR; Samary, CS; Santos, CL; Silva, PL; Villela, N | 1 |
| Charlton, NP; Rushton, WF | 1 |
| Chen, Z; Lin, S; Shao, W | 1 |
| Akeju, O; Brown, EN; Gao, L; Habeeb, K; Harrell, PG; Hartnack, KE; Lei, G; Pavone, KJ; Pierce, ET; Prerau, MJ; Purdon, PL; Rhee, J; Sampson, AL; Vazquez, R; Walsh, JL; Westover, MB | 1 |
| Baek, J; Joo, J; Lee, J | 1 |
| Kim, JY; Kwak, HJ | 1 |
| Ahmed, S; Burgoyne, LL; Chooi, C; Costi, D; Cyna, AM; Ellwood, J; Larsson, JN; Middleton, P; Stephens, K; Strickland, P | 1 |
| Hwang, JW; Jeon, YT; Kang, MH; Lee, HJ; Lim, YJ; Park, HP | 1 |
| Georgiadis, S; Jääskeläinen, SK; Karjalainen, P; Kaskinoro, K; Långsjö, J; Maksimow, A; Scheinin, H | 1 |
| Allen, JC; Bong, CL; Choo, WL; Lim, E; Siow, YN; Tan, JS; Teo, PB | 1 |
| Li, P; Shen, P; Zhou, P | 1 |
| Du, H; He, Y; Kou, D; Li, Z; Wang, Z; Yu, W | 1 |
| He, L; He, T; Liu, L; Xu, JM; Zhu, R | 1 |
| Hwang, JW; Jang, YE; Jeon, YT; Kim, E; Kim, YC; Park, HP; Yoon, HK | 1 |
| Asano, N; Ikemoto, K; Ishiyama, T; Kotoda, M; Matsukawa, T; Sessler, DI; Shintani, N; Terada, Y | 1 |
| Jena, S; Mittal, M; Reddy, M; Sriganesh, K; Umamaheswara Rao, GS | 1 |
| Bergfeld, C; Beyerbach, M; Kästner, SB; Voigt, AM | 1 |
| Benedict, NJ; Kane-Gill, SL; Wong, A | 1 |
| Cheung, CW; Chu, KM; Irwin, MG; Liu, J; Qiu, Q | 1 |
| Bai, Y; Jia, L; Li, H; Zhu, X | 1 |
| Coté, CJ; Cravero, JP | 1 |
| Huang, F; Jin, J; Kong, J; Liu, S; Wang, J; Xu, H; Yang, X | 1 |
| Abud, B; Cakmak, M; Gonullu, M; Karaman, Y; Tekgul, ZT; Yildiz, M | 1 |
| Abdel-Ma'boud, MA | 1 |
| Cho, HJ; Cho, JS; Kim, EJ; Kim, HJ; Koo, BN; Shin, S; Soh, S | 1 |
| Bharadwaj, S; Venkatraghavan, L | 1 |
| Ding, Z; Han, C; Jiang, X; Wu, X; Yu, L; Yu, M | 1 |
| Ji, J; Sun, K; Wang, G; Wang, Y; Wang, Z; Zhou, G | 1 |
| Bailey, CR; Wong, DD | 1 |
| Yamashita, K; Yatabe, T; Yokoyama, M | 1 |
| Darnobid, JA | 1 |
| Banik, S; Prabhakar, H | 1 |
| Ju, HM; Kim, H; Kim, N; Lee, SK; Min, KT; Yoo, YC | 1 |
| Bekker, A; Eloy, JD; Li, J; Nadavaluru, PR; Xiong, M; Ye, JH; Zuo, W | 1 |
| Cai, Y; Chen, K; Chen, Y; Lu, Z; Pan, SM; Xin, YC | 1 |
| Apajasalo, M; Jakob, SM; Kaukonen, KM; Ruokonen, E; Sarapohja, T; Takala, J; Turunen, H | 1 |
| Carmona, P; Carrió, M | 1 |
| Borle, A; Farid, N; Goudra, BG; Harris, K; Singh, PM | 1 |
| Hu, X; Qian, C; Wu, Y; Xie, J; Zhang, Y; Zhou, Y | 1 |
| Reddy, M; Sriganesh, K; Umamaheswara Rao, GS | 1 |
| Enomoto, Y; Hagiya, K; Kawano, S; Koyama, Y; Miya, K; Mizutani, T; Nishino, T; Shimojo, N; Yamasaki, Y | 1 |
| Chia, CS; Ng, O; Teo, MC; Thong, SY | 1 |
| Keating, GM | 1 |
| Rubenfeld, GD; Wilcox, ME | 1 |
| Guo, F; Li, Q; Liu, L; Longhini, F; Qiu, H; Yang, Y; Yu, T | 1 |
| Brown, M; Kinney, G; Lee, LA; Metzner, J; Rozet, I; Sharma, D; Slimp, JC; Treggiari, MM; Vavilala, MS | 1 |
| Diao, HX; Fan, HG; Gao, PY; Jiang, S; Li, JN; Liu, HY | 1 |
| Cho, SH; Kim, JY; Kwak, HJ; Lee, D; Park, HY | 1 |
| Cui, X; Jin, C; Jin, Z; Xu, J | 1 |
| Dupler, S; Farag, E; Gomes, J; Hussain, MS; John, S; Somal, J; Thebo, U | 1 |
| Choi, SS; Jang, DM; Joung, KW; Kim, PN; Kong, YG; Lee, HM; Shim, JH; Shin, YM; Song, MH; Won, HJ | 1 |
| Lobo, FA; Saraiva, AP | 1 |
| Akeju, O; Brown, EN; Purdon, PL; Zhou, DW | 1 |
| Deng, X; Liu, J; Sui, J; Wang, L; Wei, L | 1 |
| Lamperti, M | 1 |
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64 review(s) available for dexmedetomidine and propofol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Use of propofol and other nonbenzodiazepine sedatives in the intensive care unit.
Topics: Critical Illness; Dexmedetomidine; Etomidate; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol | 2001 |
Tolerance and withdrawal issues with sedation.
Topics: Analgesics; Benzodiazepines; Biological Availability; Conscious Sedation; Critical Care; Dexmedetomidine; Drug Administration Schedule; Drug Tolerance; Humans; Hypnotics and Sedatives; Metabolic Clearance Rate; Propofol; Substance Withdrawal Syndrome | 2005 |
Anesthesia in the patient for awake craniotomy.
Topics: Conscious Sedation; Consciousness; Craniotomy; Dexmedetomidine; Humans; Hypnotics and Sedatives; Neurologic Examination; Piperidines; Propofol; Remifentanil | 2007 |
Future directions in endoscopic sedation.
Topics: Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anesthetics, Dissociative; Conscious Sedation; Dexmedetomidine; Endoscopy, Gastrointestinal; Gastrointestinal Diseases; Humans; Ketamine; Propofol | 2008 |
Overview of total intravenous anesthesia in children.
Topics: Adolescent; Age Factors; Algorithms; Analgesics, Opioid; Anesthesia, Intravenous; Anesthetics, Intravenous; Body Weight; Child; Child, Preschool; Dexmedetomidine; Drug Delivery Systems; Humans; Infant; Infant, Newborn; Ketamine; Models, Theoretical; Propofol | 2010 |
Traumatic brain injury: neuroprotective anaesthetic techniques, an update.
Topics: Adolescent; Adult; Brain Injuries; Cell Death; Central Nervous System Depressants; Craniocerebral Trauma; Cyclosporine; Dexmedetomidine; Erythropoietin; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Intracranial Hypotension; Isoflurane; Middle Aged; Neuroprotective Agents; Nitrous Oxide; Perioperative Care; Propofol; Resuscitation; Saline Solution, Hypertonic; Xenon; Young Adult | 2009 |
Sedation trends in the 21st century: the transition to dexmedetomidine for radiological imaging studies.
Topics: Adolescent; Anesthetics, Intravenous; Child; Child, Preschool; Conscious Sedation; Contraindications; Dexmedetomidine; Diagnostic Imaging; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Propofol | 2010 |
Optimizing sustained use of sedation in mechanically ventilated patients: focus on safety.
Topics: Bradycardia; Critical Care; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Monitoring; Humans; Hypertriglyceridemia; Hypnotics and Sedatives; Propofol; Respiration, Artificial | 2010 |
Anaesthesia or sedation for MRI in children.
Topics: Anesthesia; Anesthetics, Dissociative; Anesthetics, Intravenous; Child; Chloral Hydrate; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Ketamine; Magnetic Resonance Imaging; Midazolam; Pentobarbital; Propofol | 2010 |
Sedation for radiological imaging.
Topics: Child; Chloral Hydrate; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intestinal Absorption; Ketamine; Magnetic Resonance Imaging; Midazolam; Pentobarbital; Propofol; Temazepam; Thiopental; Tomography, X-Ray Computed | 2011 |
Considerations for the use of anesthetics in neurotoxicity studies.
Topics: Anesthetics; Barbiturates; Carbon Dioxide; Dexmedetomidine; Euthanasia, Animal; Halothane; Isoflurane; Ketamine; Nervous System; Neuroprotective Agents; Nitrous Oxide; Propofol; Research; Signal Transduction; Toxicology; Xenon | 2010 |
Analgosedation in neonates: do we still need additional tools after 30 years of clinical research?
Topics: Acetaminophen; Adrenergic alpha-2 Receptor Agonists; Analgesia; Analgesics, Opioid; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant, Newborn; Midazolam; Morphine; Pain; Pain Measurement; Piperidines; Propofol; Quality of Health Care; Remifentanil | 2011 |
Pediatric sedation--evolution and revolution.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Anesthesiology; Child; Conscious Sedation; Dexmedetomidine; Excitatory Amino Acid Antagonists; Fasting; Guidelines as Topic; Humans; Hypnotics and Sedatives; Ketamine; Patient Simulation; Pediatrics; Physicians; Preoperative Care; Propofol; Quebec | 2011 |
Sedation and anesthesia issues in pediatric imaging.
Topics: Anesthesia; Anesthetics, Dissociative; Child, Preschool; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Ketamine; Magnetic Resonance Imaging; Pediatrics; Propofol | 2011 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Randomized Controlled Trials as Topic | 2013 |
Clinical policy: procedural sedation and analgesia in the emergency department.
Topics: Alfentanil; Analgesia; Anesthesia, General; Capnography; Conscious Sedation; Deep Sedation; Dexmedetomidine; Emergency Service, Hospital; Etomidate; Humans; Ketamine; Piperidines; Propofol; Remifentanil; Workforce | 2014 |
Dexmedetomidine for the management of awake fibreoptic intubation.
Topics: Adrenergic alpha-2 Receptor Agonists; Anti-Anxiety Agents; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Midazolam; Propofol; Randomized Controlled Trials as Topic; Wakefulness | 2014 |
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child; Clonidine; Desflurane; Dexmedetomidine; Halothane; Humans; Isoflurane; Methyl Ethers; Midazolam; Propofol; Sevoflurane | 2014 |
The pharmacology of total intravenous anesthesia.
Topics: Anesthetics, Intravenous; Dexmedetomidine; Humans; Ketamine; Piperidines; Propofol; Remifentanil | 2015 |
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Bradycardia; Clonidine; Conscious Sedation; Critical Illness; Dexmedetomidine; Humans; Lorazepam; Midazolam; Propofol; Randomized Controlled Trials as Topic; Respiration, Artificial; Selection Bias; Time Factors | 2015 |
Dexmedetomidine versus standard care sedation with propofol or midazolam in intensive care: an economic evaluation.
Topics: Conscious Sedation; Dexmedetomidine; Hospitalization; Humans; Hypnotics and Sedatives; Intensive Care Units; Midazolam; Propofol; Randomized Controlled Trials as Topic; Respiration, Artificial | 2015 |
Anesthesia for Advanced Bronchoscopic Procedures: State-of-the-Art Review.
Topics: Anesthesia; Anesthesia, General; Anesthetics, Local; Benzodiazepines; Bronchoscopy; Dexmedetomidine; Humans; Hypnotics and Sedatives; Monitoring, Intraoperative; Piperidines; Preoperative Care; Propofol; Remifentanil; Respiration, Artificial; Risk Assessment | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; Hypnotics and Sedatives; Propofol | 2015 |
Adult procedural sedation: an update.
Topics: Adult; Anesthesia; Benzodiazepines; Dexmedetomidine; Humans; Hypnotics and Sedatives; Piperidines; Propofol; Remifentanil | 2015 |
Treatment of Severe Alcohol Withdrawal.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Benzodiazepines; Critical Care; Dexmedetomidine; Drug Therapy, Combination; Humans; Phenobarbital; Propofol; Randomized Controlled Trials as Topic; Respiration, Artificial; Retrospective Studies; Substance Withdrawal Syndrome | 2016 |
Propofol for Treatment of Refractory Alcohol Withdrawal Syndrome: A Review of the Literature.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Alcohol-Induced Disorders, Nervous System; Bradycardia; Chemotherapy, Adjuvant; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Resistance; Evidence-Based Medicine; GABA-A Receptor Agonists; Humans; Hypnotics and Sedatives; Hypotension; Length of Stay; Practice Guidelines as Topic; Precision Medicine; Propofol; Respiration, Artificial; Severity of Illness Index | 2016 |
Update on pharmacological management of procedural sedation for children.
Topics: Administration, Intranasal; Child; Conscious Sedation; Dexmedetomidine; Etomidate; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Nitrous Oxide; Propofol | 2016 |
A forecast of relevant pediatric sedation trends.
Topics: Benzodiazepines; Child; Conscious Sedation; Dexmedetomidine; Drug Delivery Systems; Drug Discovery; Humans; Ketamine; Pharmacogenetics; Precision Medicine; Propofol | 2016 |
Sedative choice in drug-induced sleep endoscopy: A neuropharmacology-based review.
Topics: Anesthetics, Intravenous; Dexmedetomidine; Endoscopy; Humans; Hypnotics and Sedatives; Midazolam; Neuropharmacology; Propofol; Sleep; Sleep Apnea, Obstructive | 2017 |
Non-Operating Room Anesthesia in the Endoscopy Unit.
Topics: Analgesics, Opioid; Anesthesia; Anesthesiology; Benzodiazepines; Conscious Sedation; Deep Sedation; Dexmedetomidine; Endoscopy; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedatives; Intraoperative Care; Ketamine; Monitoring, Intraoperative; Operating Rooms; Postoperative Care; Propofol | 2016 |
On the Horizon: The Future of Procedural Sedation.
Topics: Anesthesia Recovery Period; Benzodiazepines; Conscious Sedation; Deep Sedation; Dexmedetomidine; Endoscopy, Gastrointestinal; Gastroenterology; Humans; Hypnotics and Sedatives; Ketamine; Patient Satisfaction; Piperidines; Propofol; Remifentanil | 2016 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence Delirium; Fentanyl; Humans; Incidence; Isoflurane; Ketamine; Methyl Ethers; Propofol; Sevoflurane | 2017 |
Dexmedetomidine vs propofol sedation reduces delirium in patients after cardiac surgery: A meta-analysis with trial sequential analysis of randomized controlled trials.
Topics: Coronary Artery Bypass; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Postoperative Complications; Propofol; Randomized Controlled Trials as Topic | 2017 |
Sedation After Cardiac Surgery: Is One Drug Better Than Another?
Topics: Analgesics, Opioid; Cardiac Surgical Procedures; Dexmedetomidine; Humans; Hypnotics and Sedatives; Pain, Postoperative; Postoperative Care; Propofol | 2017 |
Dexmedetomidine versus propofol during drug-induced sleep endoscopy and sedation: a systematic review.
Topics: Anesthesia; Dexmedetomidine; Endoscopy; Humans; Propofol; Sleep | 2017 |
Neonatal pain management.
Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Barbiturates; Chronic Pain; Cyclohexanecarboxylic Acids; Dexmedetomidine; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Neonatal; Kangaroo-Mother Care Method; Ketamine; Lorazepam; Midazolam; Neonatal Abstinence Syndrome; Pain Management; Pain Measurement; Palliative Care; Propofol; Sucking Behavior; Sucrose; Terminal Care | 2017 |
Systematic review of anaesthetic medication for ERCP based on a network meta-analysis.
Topics: Alfentanil; Analgesics, Opioid; Anesthetics; Cholangiopancreatography, Endoscopic Retrograde; Dexmedetomidine; Drug Therapy, Combination; Humans; Ketamine; Meperidine; Midazolam; Network Meta-Analysis; Operative Time; Propofol; Randomized Controlled Trials as Topic; Treatment Outcome | 2018 |
Does dexmedetomidine have an antiarrhythmic effect on cardiac patients? A meta-analysis of randomized controlled trials.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Coronary Artery Bypass; Databases, Factual; Dexmedetomidine; Heart Diseases; Humans; Intensive Care Units; Odds Ratio; Propofol; Randomized Controlled Trials as Topic; Risk Factors; Tachycardia | 2018 |
Anesthetic Agents Commonly Used by Oral and Maxillofacial Surgeons.
Topics: Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Dexmedetomidine; Diazepam; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Nitrous Oxide; Propofol; Surgery, Oral | 2018 |
Effectiveness of dexmedetomidine versus propofol on extubation times, length of stay and mortality rates in adult cardiac surgery patients: a systematic review and meta-analysis.
Topics: Adult; Airway Extubation; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Cardiac Surgical Procedures; Critical Care; Dexmedetomidine; Hospital Mortality; Humans; Intensive Care Units; Length of Stay; Propofol; Respiration, Artificial; Time Factors | 2018 |
Drug selection for ambulatory procedural sedation.
Topics: Ambulatory Surgical Procedures; Animals; Benzodiazepines; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Propofol | 2018 |
Altered Pharmacokinetics in Prolonged Infusions of Sedatives and Analgesics Among Adult Critically Ill Patients: A Systematic Review.
Topics: Adult; Analgesics; Critical Illness; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lorazepam; Midazolam; Morphine; Propofol; Remifentanil; Sufentanil; Time Factors | 2018 |
Drug-Induced Sleep Endoscopy.
Topics: Anesthetics, Intravenous; Dexmedetomidine; Endoscopy; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Phenotype; Propofol; Sleep Apnea, Obstructive | 2019 |
Awake Fiberoptic Intubation Protocols in the Operating Room for Anticipated Difficult Airway: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Topics: Analgesics, Opioid; Anesthesia, Local; Clinical Protocols; Dexmedetomidine; Fiber Optic Technology; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Midazolam; Operating Rooms; Patient Safety; Propofol; Randomized Controlled Trials as Topic; Risk; Treatment Outcome; Wakefulness | 2019 |
Moderate and deep sedation training and pharmacology for nonanesthesiologists: recommendations for effective practice.
Topics: Administration, Intravenous; Analgesics, Opioid; Anesthesiology; Apnea; Benzodiazepines; Conscious Sedation; Consciousness; Deep Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Education, Medical, Continuing; Humans; Hypnotics and Sedatives; Hypotension; Hypoventilation; Hypoxia; Practice Guidelines as Topic; Propofol | 2019 |
Effect of ancillary drugs on sevoflurane related emergence agitation in children undergoing ophthalmic surgery: a Bayesian network meta-analysis.
Topics: Akathisia, Drug-Induced; Analgesics; Anesthesia Recovery Period; Anesthetics, Inhalation; Bayes Theorem; Child; Clonidine; Dexmedetomidine; Drug Therapy, Combination; Fentanyl; Humans; Ketamine; Midazolam; Network Meta-Analysis; Ophthalmologic Surgical Procedures; Propofol; Psychomotor Agitation; Remifentanil; Sevoflurane; Sufentanil | 2019 |
Dexmedetomidine versus propofol sedation in reducing delirium among older adults in the ICU: A systematic review and meta-analysis.
Topics: Aged; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Respiration, Artificial | 2020 |
Dexmedetomidine for prevention of propofol injection pain upon induction of anesthesia: a meta-analysis.
Topics: Analgesics, Non-Narcotic; Anesthesia; Anesthetics, Intravenous; Dexmedetomidine; Humans; Pain; Propofol; Randomized Controlled Trials as Topic | 2020 |
Effect of Dexmedetomidine in children undergoing general anaesthesia with sevoflurane: a meta-analysis and systematic review.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child; Child, Preschool; China; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Methyl Ethers; Propofol; Psychomotor Agitation; Sevoflurane | 2020 |
Procedural sedation outside the operating room.
Topics: Analgesia; Anesthesia; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Ketamine; Operating Rooms; Propofol; Remifentanil | 2020 |
Critical Review and Meta-Analysis of Postoperative Sedation after Adult Cardiac Surgery: Dexmedetomidine Versus Propofol.
Topics: Adult; Cardiac Surgical Procedures; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Respiration, Artificial | 2021 |
Perioperative Diabetes Insipidus Caused by Anesthetic Medications: A Review of the Literature.
Topics: Anesthesia; Anesthetics; Dexmedetomidine; Diabetes Insipidus; Electrolytes; Humans; Hypovolemia; Incidence; Ketamine; Perioperative Period; Propofol; Retrospective Studies; Sevoflurane | 2022 |
Control of Hemodynamic Responses and Perioperative Outcomes in Transsphenoidal Pituitary Surgery: A Qualitative Systematic Review of the Available Evidence.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Dexmedetomidine; Hemodynamics; Humans; Propofol; Randomized Controlled Trials as Topic; Sevoflurane | 2022 |
Comparison of clinical efficacy and safety between dexmedetomidine and propofol among patients undergoing gastrointestinal endoscopy: a meta-analysis.
Topics: Dexmedetomidine; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedatives; Hypotension; Propofol; Treatment Outcome | 2021 |
Systematic review and meta-analysis of the sedative effects and safety of dexmedetomidine in patients after cardiac surgery.
Topics: Cardiac Surgical Procedures; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Propofol | 2021 |
The Impact of Sedative Choice on Intracranial and Systemic Physiology in Moderate to Severe Traumatic Brain Injury: A Scoping Review.
Topics: Adult; Analgesics, Opioid; Brain Injuries; Brain Injuries, Traumatic; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intracranial Hypertension; Ketamine; Propofol; Prospective Studies | 2023 |
Postoperative Application of Dexmedetomidine is the Optimal Strategy to Reduce the Incidence of Postoperative Delirium After Cardiac Surgery: A Network Meta-Analysis of Randomized Controlled Trials.
Topics: Cardiac Surgical Procedures; Dexmedetomidine; Emergence Delirium; Humans; Hypnotics and Sedatives; Incidence; Network Meta-Analysis; Postoperative Complications; Propofol; Randomized Controlled Trials as Topic | 2023 |
The Emergency Medicine Pharmacotherapy Literature of 2021.
Topics: Antipsychotic Agents; Dexmedetomidine; Diphenhydramine; Emergency Medicine; Fibrinolytic Agents; Humans; Ischemic Stroke; Propofol; Tranexamic Acid | 2022 |
Outcomes of dexmedetomidine versus propofol sedation in critically ill adults requiring mechanical ventilation: a systematic review and meta-analysis of randomised controlled trials.
Topics: Adult; Bradycardia; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Randomized Controlled Trials as Topic; Respiration, Artificial | 2022 |
The Choice of Anesthetic Drugs in Outpatient Hysteroscopic Surgery: A Systematic Review and Network Meta-Analysis.
Topics: Ambulatory Surgical Procedures; Anesthetics; Dexmedetomidine; Female; Humans; Hysteroscopy; Network Meta-Analysis; Outpatients; Pregnancy; Propofol; Respiratory Insufficiency | 2022 |
A new view on old problems in paediatric anaesthesia: premedication, postoperative agitation and dosing.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia; Anti-Anxiety Agents; Child; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Postoperative Period; Premedication; Propofol | 2023 |
Comparison of dexmedetomidine and propofol for sedation in awake craniotomy: A meta-analysis.
Topics: Conscious Sedation; Craniotomy; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol; Respiratory Insufficiency; Wakefulness | 2023 |
Modern Sedation and Analgesia Strategies in Neurocritical Care.
Topics: Analgesia; Critical Care; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Propofol; Respiration, Artificial | 2023 |
262 trial(s) available for dexmedetomidine and propofol
| Article | Year |
|---|---|
Effect of dexmedetomidine on propofol requirements in healthy subjects.
Topics: Adolescent; Adult; Cross-Over Studies; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Logistic Models; Male; Placebos; Propofol; Reference Values | 2001 |
The effect of intravenous dexmedetomidine premedication on the dose requirement of propofol to induce loss of consciousness in patients receiving alfentanil.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Alfentanil; Analysis of Variance; Anesthetics, Intravenous; Bradycardia; Chromatography, High Pressure Liquid; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Humans; Hypnotics and Sedatives; Norepinephrine; Preanesthetic Medication; Propofol; Radioimmunoassay | 2001 |
Effects of dexmedetomidine on adrenocortical function, and the cardiovascular, endocrine and inflammatory responses in post-operative patients needing sedation in the intensive care unit.
Topics: Adrenal Cortex; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Conscious Sedation; Critical Care; Dexmedetomidine; Hemodynamics; Hormones; Humans; Hypnotics and Sedatives; Interleukin-6; Middle Aged; Postoperative Care; Propofol | 2001 |
Comparison between dexmedetomidine and propofol for sedation in the intensive care unit: patient and clinician perceptions.
Topics: Adrenergic alpha-Agonists; Aged; Alfentanil; Analgesics, Opioid; Conscious Sedation; Critical Care; Dexmedetomidine; Drug Administration Schedule; Hemodynamics; Hospital Mortality; Humans; Hypnotics and Sedatives; Intensive Care Units; Intubation, Intratracheal; Middle Aged; Patient Satisfaction; Postoperative Care; Propofol; Respiration, Artificial; Surveys and Questionnaires | 2001 |
Bispectral index-guided sedation with dexmedetomidine in intensive care: a prospective, randomized, double blind, placebo-controlled phase II study.
Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Critical Care; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Morphine; Propofol; Prospective Studies | 2002 |
The efficacy, side effects, and recovery characteristics of dexmedetomidine versus propofol when used for intraoperative sedation.
Topics: Adult; Aged; Anesthesia Recovery Period; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Elective Surgical Procedures; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Intraoperative Period; Male; Middle Aged; Pain, Postoperative; Postoperative Nausea and Vomiting; Propofol; Psychomotor Performance; Respiratory Function Tests | 2002 |
24-hour Holter-monitoring in the perianaesthetic period in dogs premedicated with dexmedetomidine.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Dexmedetomidine; Dogs; Drug Interactions; Drug Monitoring; Female; Heart Rate; Hypnotics and Sedatives; Isoflurane; Male; Preanesthetic Medication; Propofol; Time Factors | 2002 |
A comparison of propofol infusion and propofol/isoflurane anaesthesia in dexmedetomidine premedicated dogs.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; beta-Endorphin; Blood Gas Analysis; Blood Pressure; Catecholamines; Dexmedetomidine; Dogs; Drug Administration Schedule; Female; Heart Rate; Hydrocortisone; Hypnotics and Sedatives; Infusions, Intravenous; Injections, Intramuscular; Isoflurane; Male; Premedication; Propofol | 2003 |
Clinical use of dexmedetomidine as premedicant in cats undergoing propofol-sevoflurane anaesthesia.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Pressure; Cats; Dexmedetomidine; Female; Heart Rate; Hypnotics and Sedatives; Hysterectomy; Infusions, Intravenous; Methyl Ethers; Ovariectomy; Premedication; Propofol; Respiration; Sevoflurane | 2003 |
ICU sedation after coronary artery bypass graft surgery: dexmedetomidine-based versus propofol-based sedation regimens.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Analgesics, Opioid; Anti-Arrhythmia Agents; Biomarkers; Blood Pressure; Blood Urea Nitrogen; Canada; Conscious Sedation; Coronary Artery Bypass; Coronary Artery Disease; Dexmedetomidine; Diuretics; Female; gamma-Glutamyltransferase; Heart Rate; Humans; Hypnotics and Sedatives; Incidence; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Morphine; Postoperative Care; Postoperative Complications; Propofol; Respiration, Artificial; Systole; Time Factors; Treatment Outcome; United States; Vasodilator Agents | 2003 |
Enhanced visual memory effect for negative versus positive emotional content is potentiated at sub-anaesthetic concentrations of thiopental.
Topics: Adult; Anesthetics, Intravenous; Dexmedetomidine; Dose-Response Relationship, Drug; Emotions; Female; GABA Modulators; Humans; Male; Mental Recall; Middle Aged; Pattern Recognition, Visual; Photic Stimulation; Propofol; Recognition, Psychology; Thiopental | 2004 |
Information loss over time defines the memory defect of propofol: a comparative response with thiopental and dexmedetomidine.
Topics: Dexmedetomidine; Electroencephalography; Female; Humans; Male; Memory Disorders; Pain Measurement; Propofol; Reaction Time; Thiopental | 2004 |
Dexmedetomidine does not improve patient satisfaction when compared with propofol during mechanical ventilation.
Topics: Coronary Artery Bypass; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Pain, Postoperative; Patient Satisfaction; Propofol; Respiration, Artificial; Surveys and Questionnaires | 2005 |
Dexmedetomidine or medetomidine premedication before propofol-desflurane anaesthesia in dogs.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Blood Pressure; Desflurane; Dexmedetomidine; Dogs; Female; Heart Rate; Hemodynamics; Hypnotics and Sedatives; Isoflurane; Male; Medetomidine; Preanesthetic Medication; Propofol; Respiration | 2006 |
A comparison of the sedative, hemodynamic, and respiratory effects of dexmedetomidine and propofol in children undergoing magnetic resonance imaging.
Topics: Blood Pressure; Child; Child, Preschool; Conscious Sedation; Dexmedetomidine; Female; Heart Rate; Humans; Hypnotics and Sedatives; Infant; Infusions, Intravenous; Magnetic Resonance Imaging; Male; Oxygen; Propofol; Respiration | 2006 |
A comparison of the effect on gastric emptying of propofol or dexmedetomidine in critically ill patients: preliminary study.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Critical Care; Dexmedetomidine; Double-Blind Method; Enteral Nutrition; Female; Gastric Emptying; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Intubation, Gastrointestinal; Male; Middle Aged; Placebos; Propofol; Prospective Studies | 2006 |
Dexmedetomidine-ketamine and propofol-ketamine combinations for anesthesia in spontaneously breathing pediatric patients undergoing cardiac catheterization.
Topics: Anesthesia Recovery Period; Anesthetics, Dissociative; Anesthetics, Intravenous; Cardiac Catheterization; Child; Child, Preschool; Conscious Sedation; Dexmedetomidine; Electroencephalography; Female; Heart Rate; Humans; Hypnotics and Sedatives; Infant; Ketamine; Male; Propofol; Respiration | 2006 |
Does dexmedetomidine reduce the injection pain due to propofol and rocuronium?
Topics: Adrenergic alpha-Agonists; Adult; Analysis of Variance; Androstanols; Anesthesia, Intravenous; Dexmedetomidine; Double-Blind Method; Elective Surgical Procedures; Humans; Hypnotics and Sedatives; Injections, Intravenous; Middle Aged; Neuromuscular Nondepolarizing Agents; Pain; Pain Measurement; Preoperative Care; Propofol; Prospective Studies; Rocuronium | 2007 |
Opioid consumption in total intravenous anesthesia is reduced with dexmedetomidine: a comparative study with remifentanil in gynecologic videolaparoscopic surgery.
Topics: Adult; Analgesics, Opioid; Anesthesia, Intravenous; Blood Glucose; Blood Pressure; Dexmedetomidine; Female; Gynecologic Surgical Procedures; Humans; Hydrocortisone; Laparoscopy; Middle Aged; Piperidines; Postoperative Nausea and Vomiting; Propofol; Remifentanil; Single-Blind Method | 2007 |
Dexmedetomidine blunts acute hyperdynamic responses to electroconvulsive therapy without altering seizure duration.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Blood Pressure; Cross-Over Studies; Dexmedetomidine; Double-Blind Method; Electroconvulsive Therapy; Female; Heart Rate; Humans; Male; Middle Aged; Neuromuscular Depolarizing Agents; Propofol; Seizures; Sodium Chloride; Succinylcholine; Time Factors | 2008 |
Effects of dexmedetomidine in morbidly obese patients undergoing laparoscopic gastric bypass.
Topics: Adrenergic alpha-Agonists; Aged; Analgesics, Opioid; Anastomosis, Roux-en-Y; Anesthesia, Intravenous; Anesthetics; Anesthetics, Intravenous; Blood Pressure; Body Mass Index; Dexmedetomidine; Female; Gastric Bypass; Heart Rate; Humans; Laparoscopy; Male; Middle Aged; Monitoring, Intraoperative; Morphine; Obesity, Morbid; Pain, Postoperative; Preanesthetic Medication; Propofol | 2007 |
A comparison of sedation with dexmedetomidine or propofol during shockwave lithotripsy: a randomized controlled trial.
Topics: Adult; Analgesics; Conscious Sedation; Consciousness; Dexmedetomidine; Double-Blind Method; Female; Fentanyl; Hemodynamics; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lithotripsy; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Propofol; Respiratory Mechanics; Treatment Outcome | 2008 |
Comparative effects of propofol vs dexmedetomidine on cerebrovascular carbon dioxide reactivity in patients with septic shock.
Topics: Aged; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulation; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Middle Aged; Middle Cerebral Artery; Propofol; Prospective Studies; Respiration, Artificial; Shock, Septic; Ultrasonography, Doppler, Transcranial | 2008 |
Dexmedetomidine constant rate infusion for 24 hours during and after propofol or isoflurane anaesthesia in dogs.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Cross-Over Studies; Dexmedetomidine; Dogs; Female; Heart Rate; Hypnotics and Sedatives; Infusions, Intravenous; Isoflurane; Male; Oxygen; Propofol; Prospective Studies; Respiration; Treatment Outcome | 2008 |
Clinical efficacy of dexmedetomidine alone is less than propofol for conscious sedation during ERCP.
Topics: Adult; Aged; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Follow-Up Studies; Hemodynamics; Humans; Hypnotics and Sedatives; Injections, Intravenous; Intraoperative Care; Male; Middle Aged; Propofol; Treatment Outcome | 2008 |
Comparison of dexmedetomidine-propofol vs. fentanyl-propofol for laryngeal mask insertion.
Topics: Adult; Aged; Analysis of Variance; Anesthetics, Combined; Blood Pressure; Dexmedetomidine; Female; Fentanyl; Humans; Intubation, Intratracheal; Laryngeal Masks; Male; Middle Aged; Motor Activity; Propofol; Prospective Studies; Respiration; Time Factors | 2008 |
[Postoperative management of carotid endarterectomy with dexmedetomidine--a comparison with propofol].
Topics: Aged; Dexmedetomidine; Endarterectomy, Carotid; Female; Humans; Hypnotics and Sedatives; Male; Postoperative Care; Propofol | 2008 |
Dexmedetomidine versus propofol/midazolam for long-term sedation during mechanical ventilation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Pilot Projects; Propofol; Respiration, Artificial; Time Factors; Young Adult | 2009 |
A comparison of dexmedetomidine-midazolam with propofol for maintenance of anesthesia in children undergoing magnetic resonance imaging.
Topics: Anesthesia; Blood Pressure; Child; Child, Preschool; Dexmedetomidine; Female; Health Care Costs; Heart Rate; Humans; Hypnotics and Sedatives; Infant; Magnetic Resonance Imaging; Male; Midazolam; Propofol; Respiration | 2008 |
Recovery profiles from dexmedetomidine as a general anesthetic adjuvant in patients undergoing lower abdominal surgery.
Topics: Abdomen; Adjuvants, Anesthesia; Adult; Anesthesia Recovery Period; Anesthesia, General; Dexmedetomidine; Electroencephalography; Humans; Methyl Ethers; Middle Aged; Propofol; Sevoflurane | 2008 |
Propofol and midazolam inhibit conscious memory processes very soon after encoding: an event-related potential study of familiarity and recollection in volunteers.
Topics: Adolescent; Adult; Conscious Sedation; Data Interpretation, Statistical; Dexmedetomidine; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials; Female; Humans; Hypnotics and Sedatives; Male; Memory; Mental Recall; Midazolam; Middle Aged; Photic Stimulation; Propofol; Psychomotor Performance; Reaction Time; Thiopental; Young Adult | 2009 |
Premedication with dexmedetomidine and midazolam attenuates agitation after electroconvulsive therapy.
Topics: Adult; Anesthesia; Bipolar Disorder; Blood Pressure; Depressive Disorder, Major; Dexmedetomidine; Electroconvulsive Therapy; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Premedication; Propofol; Psychomotor Agitation; Respiratory Insufficiency; Seizures | 2009 |
Remifentanil-propofol vs dexmedetomidine-propofol--anesthesia for supratentorial craniotomy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Intravenous; Blood Pressure; Cognition; Craniotomy; Dexmedetomidine; Double-Blind Method; Electroencephalography; Heart Rate; Humans; Middle Aged; Piperidines; Postoperative Complications; Propofol; Prospective Studies; Remifentanil; Tramadol; Young Adult | 2009 |
Dexmedetomidine suppresses the decrease in blood pressure during anesthetic induction and blunts the cardiovascular response to tracheal intubation.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Anesthetics, Intravenous; Blood Pressure; Cardiovascular Diseases; Cardiovascular Surgical Procedures; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fentanyl; Heart Rate; Humans; Intubation, Intratracheal; Male; Middle Aged; Pilot Projects; Propofol; Prospective Studies | 2009 |
Psychosedation with dexmedetomidine hydrochloride during minor oral surgery.
Topics: Adult; Anesthesia, Dental; Blood Pressure; Conscious Sedation; Consciousness; Dexmedetomidine; Diastole; Female; Heart Rate; Humans; Hypnotics and Sedatives; Injections, Intravenous; Male; Memory; Minor Surgical Procedures; Oral Surgical Procedures; Oxygen; Propofol; Systole | 2009 |
Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: a randomized controlled trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study).
Topics: Adrenergic alpha-Agonists; Aged; Analgesics, Opioid; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Intra-Aortic Balloon Pumping; Male; Morphine; Pain, Postoperative; Postoperative Care; Propofol | 2009 |
Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis.
Topics: Abdomen; Adrenergic alpha-Agonists; Adult; Aged; Dexmedetomidine; Female; Hospitals, University; Humans; Hypnotics and Sedatives; Inflammation; Infusions, Intravenous; Interleukin-1; Interleukin-6; Male; Middle Aged; Pilot Projects; Pressure; Propofol; Prospective Studies; Respiration, Artificial; Sepsis; Severity of Illness Index; Tumor Necrosis Factor-alpha; Young Adult | 2009 |
Use of dexmedetomidine for primary sedation in a general intensive care unit.
Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Clinical Nursing Research; Clinical Protocols; Conscious Sedation; Critical Care; Dexmedetomidine; Drug Monitoring; Drug Utilization; Humans; Hypnotics and Sedatives; Kansas; Length of Stay; Lorazepam; Midazolam; Nursing Assessment; Propofol; Respiration, Artificial; Safety; Treatment Outcome | 2010 |
The correlation between bispectral index and observational sedation scale in volunteers sedated with dexmedetomidine and propofol.
Topics: Adult; Blood Gas Analysis; Blood Pressure Determination; Consciousness; Consciousness Monitors; Cross-Over Studies; Dexmedetomidine; Electrocardiography; Electroencephalography; Female; Heart Rate; Humans; Hypnotics and Sedatives; Infusion Pumps; Male; Monitoring, Physiologic; Observation; Predictive Value of Tests; Propofol; Respiratory Mechanics; ROC Curve; Signal Processing, Computer-Assisted; Time Factors; Wakefulness; Young Adult | 2009 |
A comparison of propofol and dexmedetomidine for intravenous sedation: a randomized, crossover study of the effects on the central and autonomic nervous systems.
Topics: Adult; Anxiety; Autonomic Nervous System; Central Nervous System; Conscious Sedation; Consciousness Monitors; Cross-Over Studies; Dexmedetomidine; Heart Rate; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Mental Processes; Oxygen; Propofol; Salivary alpha-Amylases | 2010 |
Effects of dexmedetomidine and propofol on lower esophageal sphincter and gastroesophageal pressure gradient in healthy volunteers.
Topics: Adolescent; Adult; Cross-Over Studies; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Esophageal Sphincter, Lower; Esophagus; Female; Humans; Hypnotics and Sedatives; Male; Manometry; Pressure; Propofol; Stomach; Young Adult | 2010 |
[Effect of dexmedetomidine on anesthetic requirements in cardiovascular surgery].
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Cardiovascular Surgical Procedures; Dexmedetomidine; Female; Fentanyl; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Propofol | 2009 |
A comparison of the effectiveness of dexmedetomidine versus propofol target-controlled infusion for sedation during fibreoptic nasotracheal intubation.
Topics: Adult; Blood Pressure; Conscious Sedation; Dexmedetomidine; Female; Fiber Optic Technology; Heart Rate; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intubation, Intratracheal; Male; Middle Aged; Nasal Cavity; Propofol | 2010 |
[Effect of dexmedetomidine on bispectral index and auditory evoked potential index during anesthesia with target controlled infusion of propofol and remifentanyl].
Topics: Adrenergic alpha-Agonists; Adult; Androstanols; Anesthetics, Combined; Anesthetics, Intravenous; Dexmedetomidine; Double-Blind Method; Evoked Potentials, Auditory; Female; Humans; Infusions, Intravenous; Male; Medetomidine; Middle Aged; Monitoring, Intraoperative; Neuromuscular Nondepolarizing Agents; Piperidines; Propofol; Remifentanil; Rocuronium; Thyroidectomy | 2010 |
Propofol/dexmedetomidine and propofol/ketamine combinations for anesthesia in pediatric patients undergoing transcatheter atrial septal defect closure: a prospective randomized study.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Cardiac Catheterization; Child; Child, Preschool; Dexmedetomidine; Drug Combinations; Female; Heart Septal Defects, Atrial; Hemodynamics; Humans; Hypnotics and Sedatives; Ketamine; Male; Propofol; Prospective Studies | 2010 |
Effects of fentanyl-lidocaine-propofol and dexmedetomidine-lidocaine-propofol on tracheal intubation without use of muscle relaxants.
Topics: Adult; Anesthetics, Intravenous; Blood Pressure; Dexmedetomidine; Drug Combinations; Female; Fentanyl; Heart Rate; Humans; Intubation, Intratracheal; Lidocaine; Male; Middle Aged; Propofol; Young Adult | 2010 |
Dexmedetomidine versus fentanyl as adjuvant to propofol: comparative study in children undergoing extracorporeal shock wave lithotripsy.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Intravenous; Blood Pressure; Child; Child, Preschool; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fentanyl; Heart Rate; Humans; Lithotripsy; Male; Postoperative Complications; Propofol; Prospective Studies; Time Factors | 2010 |
Sedation with dexmedetomidine hydrochloride during endoscopic submucosal dissection of gastric cancer.
Topics: Adenocarcinoma; Adenoma; Aged; Aged, 80 and over; Arousal; Conscious Sedation; Dexmedetomidine; Dissection; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gastric Mucosa; Gastroscopy; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Midazolam; Middle Aged; Neoplasm Staging; Propofol; Prospective Studies; Stomach Neoplasms | 2011 |
Hemodynamic characteristics of midazolam, propofol, and dexmedetomidine in healthy volunteers.
Topics: Adult; Blood Pressure; Dexmedetomidine; Female; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Propofol; Prospective Studies; Respiration; Single-Blind Method | 2011 |
Dexmedetomidine can stabilize hemodynamics and spare anesthetics before cardiopulmonary bypass.
Topics: Aged; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Blood Pressure; Cardiopulmonary Bypass; Dexmedetomidine; Female; Fentanyl; Hemodynamics; Humans; Male; Middle Aged; Propofol; Sternotomy | 2011 |
Comparison between propofol and dexmedetomidine in postoperative sedation after extensive cervical spine surgery.
Topics: Adult; Aged; Aged, 80 and over; Atropine; Blood Pressure; Cervical Vertebrae; Dexmedetomidine; Dopamine; Female; Heart Rate; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Male; Middle Aged; Movement; Pain; Postoperative Care; Propofol | 2012 |
Randomized double-blind study of remifentanil and dexmedetomidine for flexible bronchoscopy.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Blood Pressure; Bronchoscopy; Conscious Sedation; Cough; Dexmedetomidine; Double-Blind Method; Female; Heart Rate; Humans; Hypnotics and Sedatives; Hypoxia; Male; Middle Aged; Oxygen; Partial Pressure; Patient Satisfaction; Piperidines; Propofol; Remifentanil; Young Adult | 2012 |
Intravenous sedation for implant surgery: midazolam, butorphanol, and dexmedetomidine versus midazolam, butorphanol, and propofol.
Topics: Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Intravenous; Butorphanol; Conscious Sedation; Dental Implantation, Endosseous; Dental Implants; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Memory; Mental Recall; Midazolam; Middle Aged; Operative Time; Patient Satisfaction; Postural Balance; Propofol; Psychomotor Performance; Treatment Outcome | 2014 |
[Clinical observation of injection of dexmedetomidine in anaesthesia for esophageal cancer operation].
Topics: Adjuvants, Anesthesia; Adult; Aged; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Dexmedetomidine; Esophageal Neoplasms; Female; Fentanyl; Humans; Male; Middle Aged; Propofol | 2011 |
Clinical efficacy and safety of dexmedetomidine used as a preanesthetic prior to general anesthesia in cats.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Combined; Animals; Blood Gas Analysis; Cats; Dexmedetomidine; Female; Heart Rate; Hypnotics and Sedatives; Isoflurane; Ketamine; Male; Pain, Postoperative; Preanesthetic Medication; Propofol; Respiratory Rate | 2012 |
Is the addition of dexmedetomidine to a ketamine-propofol combination in pediatric cardiac catheterization sedation useful?
Topics: Anesthetics, Dissociative; Cardiac Catheterization; Chi-Square Distribution; Child; Child, Preschool; Dexmedetomidine; Drug Combinations; Female; Humans; Hypnotics and Sedatives; Infant; Ketamine; Propofol; Statistics, Nonparametric | 2012 |
Heart rate variability dynamics during low-dose propofol and dexmedetomidine anesthesia.
Topics: Adult; Analgesics, Non-Narcotic; Anesthesia, Intravenous; Anesthetics, Intravenous; Dexmedetomidine; Heart Rate; Humans; Male; Models, Cardiovascular; Propofol | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Male; Midazolam; Middle Aged; Nurse-Patient Relations; Pain; Pain Measurement; Propofol; Respiration, Artificial; Time Factors | 2012 |
Comparison of the effectiveness of dexmedetomidine versus propofol target-controlled infusion for sedation during coblation-assisted upper airway procedure.
Topics: Adult; Conscious Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol | 2012 |
The effect of intraoperative infusion of dexmedetomidine on the quality of recovery after major spinal surgery.
Topics: Adrenergic alpha-Agonists; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; C-Reactive Protein; Cognition; Cytokines; Dexmedetomidine; Double-Blind Method; Fatigue; Female; Fentanyl; Humans; Hydrocortisone; Infusions, Intravenous; Intraoperative Care; Male; Memory; Middle Aged; Neuropsychological Tests; Propofol; Prospective Studies; Spine; Surveys and Questionnaires | 2013 |
Correlation between bispectral index, observational sedation scale, and lower esophageal sphincter pressure in volunteers using dexmedetomidine or propofol.
Topics: Adult; Conscious Sedation; Consciousness Monitors; Dexmedetomidine; Esophageal Sphincter, Lower; Humans; Hypnotics and Sedatives; Pressure; Propofol; Young Adult | 2012 |
Effects of different loading doses of dexmedetomidine on bispectral index under stepwise propofol target-controlled infusion.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Consciousness Monitors; Dexmedetomidine; Double-Blind Method; Female; Heart Rate; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Middle Aged; Oximetry; Propofol; Respiratory Rate | 2013 |
A randomised controlled trial of dexmedetomidine for suspension laryngoscopy.
Topics: Adult; Analgesics, Opioid; Anesthesia; Anesthesia, General; Anesthesia, Intravenous; Bradycardia; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Laryngoscopy; Male; Middle Aged; Monitoring, Intraoperative; Nerve Block; Piperidines; Propofol; Remifentanil; Sample Size; Tachycardia; Young Adult | 2013 |
Evaluation of a ketamine-propofol drug combination with or without dexmedetomidine for intravenous anesthesia in cats undergoing ovariectomy.
Topics: Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Cats; Dexmedetomidine; Drug Therapy, Combination; Female; Hypnotics and Sedatives; Ketamine; Ovariectomy; Propofol | 2012 |
A pilot study of cerebral and haemodynamic physiological changes during sedation with dexmedetomidine or propofol in patients with acute brain injury.
Topics: Body Temperature; Brain Injuries; Consciousness Monitors; Cross-Over Studies; Dexmedetomidine; Glasgow Coma Scale; Humans; Hypnotics and Sedatives; Intracranial Pressure; Lactic Acid; Microdialysis; Oximetry; Pilot Projects; Propofol; Prospective Studies; Pyruvic Acid; Respiration, Artificial; Trauma Severity Indices | 2012 |
Hemodynamic effects of dexmedetomidine--fentanyl vs. nalbuphine--propofol in plastic surgery.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Blood Pressure; Dexmedetomidine; Drug Therapy, Combination; Fentanyl; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Midazolam; Middle Aged; Nalbuphine; Oxygen; Plastic Surgery Procedures; Propofol; Respiratory Insufficiency | 2012 |
Dexmedetomidine use in direct laryngoscopic biopsy under TIVA.
Topics: Adult; Aged; Analgesics; Androstanols; Anesthesia, Intravenous; Biopsy; Blood Pressure; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Laryngeal Neoplasms; Laryngoscopy; Male; Middle Aged; Pain, Postoperative; Propofol; Rocuronium | 2012 |
Dexmedetomidine impairs success of patient-controlled sedation in alcoholics during ERCP: a randomized, double-blind, placebo-controlled study.
Topics: Alcoholism; Alfentanil; Anesthetics, Intravenous; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Middle Aged; Pain; Patient Satisfaction; Propofol; Prospective Studies | 2013 |
Effects of dexmedetomidine on performance of bispectral index as an indicator of loss of consciousness during propofol administration.
Topics: Adult; Anesthetics, Intravenous; Consciousness Monitors; Deep Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Middle Aged; Propofol; ROC Curve; Unconsciousness | 2013 |
A comparison of dexmedetomidine and propofol in Patients undergoing electrophysiology study.
Topics: Adult; Anesthetics, Intravenous; Arousal; Catheter Ablation; Conscious Sedation; Developing Countries; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrophysiologic Techniques, Cardiac; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol; Respiration; Thailand | 2013 |
[Effects of dexmedetomidine on sedation and β-endorphin in traumatic brain injury: a comparative study with propofol].
Topics: Adult; beta-Endorphin; Blood Pressure; Brain Injuries; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol | 2013 |
Early goal-directed sedation versus standard sedation in mechanically ventilated critically ill patients: a pilot study*.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Airway Extubation; Algorithms; APACHE; Benzodiazepines; Conscious Sedation; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Drug Utilization; Feasibility Studies; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Pilot Projects; Propofol; Prospective Studies; Respiration, Artificial; Restraint, Physical | 2013 |
Comparison of sedation scores and propofol induction doses in dogs after intramuscular premedication with butorphanol and either dexmedetomidine or medetomidine.
Topics: Anesthesia, General; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Butorphanol; Conscious Sedation; Dexmedetomidine; Dogs; Female; Hypnotics and Sedatives; Injections, Intramuscular; Male; Medetomidine; Preanesthetic Medication; Propofol | 2013 |
[Dexmedetomidine improves oxygenation during one-lung ventilation in balanced anesthesia with propofol-fentanyl in adults].
Topics: Adult; Balanced Anesthesia; Blood Gas Analysis; Dexmedetomidine; Female; Fentanyl; Humans; Male; Middle Aged; One-Lung Ventilation; Propofol | 2013 |
Comparison of propofol-based sedation regimens administered during colonoscopy.
Topics: Adolescent; Adult; Aged; Clinical Protocols; Colonoscopy; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Meperidine; Midazolam; Middle Aged; Patient Satisfaction; Propofol; Single-Blind Method; Sufentanil; Young Adult | 2013 |
The effects of propofol and dexmedetomidine infusion on fluid responsiveness in critically ill patients.
Topics: Aged; Aged, 80 and over; Critical Illness; Dexmedetomidine; Female; Fluid Therapy; Hemodynamics; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Leg; Male; Middle Aged; Posture; Propofol; Prospective Studies; Shock; Single-Blind Method; Treatment Outcome | 2013 |
Sedation for paediatric transcatheter atrial septal defect closure: comparison of two sedation protocols.
Topics: Adolescent; Anesthesia, Intravenous; Anesthetics, Intravenous; Cardiac Catheterization; Cardiac Surgical Procedures; Child; Child, Preschool; Dexmedetomidine; Female; Heart Septal Defects, Atrial; Humans; Hypnotics and Sedatives; Male; Propofol; Treatment Outcome | 2014 |
Comparison of propofol-dexmedetomidine, tiopental-dexmedetomidine and etomidate-dexmedetomidine combinations' effects on the tracheal intubation conditions without using muscle relaxants.
Topics: Adolescent; Adult; Anesthetics, Intravenous; Dexmedetomidine; Etomidate; Female; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Male; Middle Aged; Propofol; Thiopental; Young Adult | 2013 |
Effect of increasing depth of dexmedetomidine and propofol anesthesia on upper airway morphology in children and adolescents with obstructive sleep apnea.
Topics: Adolescent; Analysis of Variance; Anesthesia; Anesthetics, Intravenous; Child; Child, Preschool; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Hospitals, University; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Male; Polysomnography; Propofol; Prospective Studies; Severity of Illness Index; Single-Blind Method; Sleep Apnea, Obstructive | 2013 |
Dexmedetomidine preserves attention/calculation when used for cooperative and short-term intensive care unit sedation.
Topics: Attention; Cognition; Conscious Sedation; Cross-Over Studies; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Propofol; Prospective Studies | 2013 |
Comparison of dexmedetomidine and propofol for conscious sedation in awake craniotomy: a prospective, double-blind, randomized, and controlled clinical trial.
Topics: Anesthesia Recovery Period; Conscious Sedation; Craniotomy; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Male; Middle Aged; Propofol; Prospective Studies | 2013 |
Propofol and dexmedetomidine for monitored anesthesia care during laser in situ keratomileusis.
Topics: Adolescent; Adult; Analysis of Variance; Anesthesia; Anxiety; Arterial Pressure; Conscious Sedation; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Keratomileusis, Laser In Situ; Male; Oxygen; Patient Satisfaction; Propofol; Young Adult | 2014 |
Safety and effectiveness using dexmedetomidine versus propofol TCI sedation during oesophagus interventions: a randomized trial.
Topics: Barrett Esophagus; Catheter Ablation; Conscious Sedation; Dexmedetomidine; Esophagoscopy; Esophagus; Humans; Hypnotics and Sedatives; Mucous Membrane; Pain, Postoperative; Patient Satisfaction; Propofol; Treatment Outcome | 2013 |
Efficacy and safety of dexmedetomidine versus propofol for the sedation of tube-retention after oral maxillofacial surgery.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Blood Pressure; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Hypoxia; Injections, Intravenous; Intubation, Intratracheal; Middle Aged; Oral Surgical Procedures; Propofol; Young Adult | 2014 |
Low-dose dexmedetomidine reduces emergence agitation after desflurane anaesthesia in children undergoing strabismus surgery.
Topics: Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child, Preschool; Desflurane; Dexmedetomidine; Female; Fentanyl; Humans; Infant; Intraoperative Period; Isoflurane; Male; Ophthalmologic Surgical Procedures; Propofol; ROC Curve; Strabismus | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric Surgery; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Ketamine; Male; Middle Aged; Postoperative Nausea and Vomiting; Propofol; Prospective Studies; Severity of Illness Index | 2014 |
Dexmedetomidine reduces propofol and remifentanil requirements during bispectral index-guided closed-loop anesthesia: a double-blind, placebo-controlled trial.
Topics: Adult; Aged; Algorithms; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Atracurium; Consciousness Monitors; Dexmedetomidine; Double-Blind Method; Ephedrine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Intraoperative Period; Male; Middle Aged; Neuromuscular Nondepolarizing Agents; Piperidines; Propofol; Remifentanil; Vasoconstrictor Agents | 2014 |
Preemptive dexmedetomidine to prevent propofol injection pain in children.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Child; Child, Preschool; Dexmedetomidine; Double-Blind Method; Elective Surgical Procedures; Female; Humans; Lidocaine; Male; Midazolam; Pain; Pain Measurement; Propofol | 2015 |
Comparison of propofol and dexmedetomedine techniques in children undergoing magnetic resonance imaging.
Topics: Anesthesia Recovery Period; Blood Pressure; Child; Child, Preschool; Dexmedetomidine; Female; Heart Rate; Humans; Hypnotics and Sedatives; Infant; Magnetic Resonance Imaging; Male; Patient Satisfaction; Propofol; Time Factors | 2014 |
Dexmedetomidine could enhance surgical satisfaction in Trans-sphenoidal resection of pituitary adenoma.
Topics: Adenoma; Adult; Aged; Anesthesia; Dexmedetomidine; Female; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Personal Satisfaction; Pituitary Neoplasms; Propofol | 2017 |
The median effective dose of dexmedetomidine for laryngeal mask airway insertion with propofol 2.0 mg/kg.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adult; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Apnea; Bradycardia; Cough; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Gagging; Gynecologic Surgical Procedures; Hemodynamics; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Laryngeal Masks; Laryngismus; Male; Middle Aged; Orthopedic Procedures; Preanesthetic Medication; Propofol; Young Adult | 2014 |
Cardiopulmonary effects of dexmedetomidine and ketamine infusions with either propofol infusion or isoflurane for anesthesia in horses.
Topics: Animals; Blood Pressure; Body Temperature; Cross-Over Studies; Dexmedetomidine; Female; Heart Rate; Horses; Isoflurane; Ketamine; Male; Propofol | 2015 |
Remifentanil requirements for preventing motor response to skin incision in healthy women anesthetized with combinations of propofol and dexmedetomidine titrated to similar Bispectral Index (BIS) values.
Topics: Adult; Analgesics, Opioid; Anesthesia, General; Anesthetics, Intravenous; Dexmedetomidine; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Middle Aged; Piperidines; Propofol; Remifentanil; Skin; Young Adult | 2015 |
Effects on somatosensory and motor evoked potentials of senile patients using different doses of dexmedetomidine during spine surgery.
Topics: Aged; Aged, 80 and over; Anesthesia; Dexmedetomidine; Evoked Potentials, Motor; Evoked Potentials, Somatosensory; Female; Fentanyl; Humans; Male; Monitoring, Physiologic; Propofol | 2015 |
Dexmedetomidine reduces pain associated with rocuronium injection without causing a decrease in BIS values: a dose-response study.
Topics: Adult; Analgesics, Non-Narcotic; Androstanols; Anesthesia, General; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Female; Humans; Injections, Intravenous; Male; Middle Aged; Monitoring, Intraoperative; Neuromuscular Nondepolarizing Agents; Pain; Pain Measurement; Premedication; Propofol; Rocuronium; Young Adult | 2014 |
Preoperative dexmedetomidine attenuates hemodynamic responses to hydrodissection in patients undergoing robotic thyroidectomy.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Dexmedetomidine; Double-Blind Method; Female; Hemodynamics; Humans; Male; Middle Aged; Perioperative Care; Piperidines; Propofol; Prospective Studies; Remifentanil; Robotics; Thyroidectomy; Young Adult | 2015 |
A comparison of single-dose dexmedetomidine or propofol on the incidence of emergence delirium in children undergoing general anaesthesia for magnetic resonance imaging.
Topics: Anesthesia Recovery Period; Anesthesia, General; Child; Child, Preschool; Delirium; Dexmedetomidine; Drug Administration Schedule; Female; Humans; Hypnotics and Sedatives; Injections, Intravenous; Magnetic Resonance Imaging; Male; Propofol; Time Factors | 2015 |
[Feasibility study for the dexmetomidine utend the drug induced sleep endoscopy].
Topics: Adult; Dexmedetomidine; Endoscopy; Feasibility Studies; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol; Sleep | 2014 |
Dexmedetomidine pretreatment alleviates propofol injection pain.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Dexmedetomidine; Double-Blind Method; Female; Humans; Injections, Intravenous; Male; Middle Aged; Pain; Pain Management; Pain Measurement; Propofol; Prospective Studies; Triglycerides; Young Adult | 2014 |
A randomized controlled trial of the effect of preoperative dexmedetomidine on the half maximal effective concentration of propofol for successful i-gel insertion without muscle relaxants.
Topics: Adult; Anesthesia, General; Bradycardia; Cough; Dexmedetomidine; Female; Heart Rate; Humans; Hypotension; Male; Middle Aged; Propofol | 2015 |
A comparative study of dexmedetomidine and propofol as sole sedative agents for patients with aneurysmal subarachnoid hemorrhage undergoing diagnostic cerebral angiography.
Topics: Adult; Aged; Cerebral Angiography; Dexmedetomidine; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol; Prospective Studies; Subarachnoid Hemorrhage | 2015 |
[Evaluation of heart rate variability for monitoring the depth of anaesthesia in dogs. Investigations based on total intravenous anaesthesia using propofol alone or in combination with dexmedetomidine or remifentanil].
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Cross-Over Studies; Dexmedetomidine; Dogs; Drug Therapy, Combination; Electrocardiography; Heart Rate; Monitoring, Intraoperative; Piperidines; Propofol; Remifentanil | 2015 |
Intranasal dexmedetomidine in combination with patient-controlled sedation during upper gastrointestinal endoscopy: a randomised trial.
Topics: Administration, Intranasal; Adult; Alfentanil; Analgesia, Patient-Controlled; Analgesics, Opioid; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Endoscopy, Gastrointestinal; Female; Humans; Hypnotics and Sedatives; Male; Patient Satisfaction; Propofol; Sodium Chloride | 2015 |
[Investigation of adjuvant treatment for difficult weaning from mechanical ventilation].
Topics: Blood Pressure; Dexmedetomidine; Furosemide; Humans; Hypnotics and Sedatives; Length of Stay; Oximetry; Propofol; Prospective Studies; Respiration, Artificial; Single-Blind Method; Solanaceous Alkaloids; Ventilator Weaning | 2014 |
[Sedative effects of dexmedetomidine in post-operative elder patients on mechanical ventilation].
Topics: Aged; Analgesics; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Postoperative Care; Postoperative Period; Propofol; Respiration, Artificial; Time Factors | 2014 |
Effects of dexmedetomidine and propofol on sedation in patients after coronary artery bypass graft surgery in a fast-track recovery room setting.
Topics: Aged; Airway Extubation; Anesthesia; Anesthesia Recovery Period; Coronary Artery Bypass; Dexmedetomidine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol; Prospective Studies; Recovery Room; Respiration | 2015 |
Comparison of three sedation regimens for drug-induced sleep endoscopy.
Topics: Adult; Airway Resistance; Conscious Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endoscopy; Female; Humans; Male; Middle Aged; Oxygen; Piperidines; Polysomnography; Propofol; Remifentanil; Sleep Apnea, Obstructive | 2015 |
Effect and Placental Transfer of Dexmedetomidine During Caesarean Section Under General Anaesthesia.
Topics: Adult; Anesthesia, General; Blood Gas Analysis; Cesarean Section; Dexmedetomidine; Drug Interactions; Female; Fentanyl; Hemodynamics; Humans; Hypnotics and Sedatives; Piperidines; Placenta; Pregnancy; Propofol; Remifentanil; Young Adult | 2015 |
[Application of dexmedetomidine combined with propofol in patients undergoing painless colonoscopy for colonic polyps resection under Narcotrend monitoring].
Topics: Anesthesia; Arterial Pressure; Colonic Polyps; Colonoscopy; Dexmedetomidine; Heart Rate; Humans; Propofol | 2015 |
Comparison of the efficacy and safety of sedation between dexmedetomidine-remifentanil and propofol-remifentanil during endoscopic submucosal dissection.
Topics: Aged; Dexmedetomidine; Dissection; Double-Blind Method; Female; Gastric Mucosa; Gastroscopy; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperidines; Propofol; Remifentanil; Republic of Korea; Stomach Neoplasms; Treatment Outcome | 2015 |
A comparison of propofol vs. dexmedetomidine for sedation, haemodynamic control and satisfaction, during esophagogastroduodenoscopy under conscious sedation.
Topics: Adult; Anesthesia Recovery Period; Conscious Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Endoscopy, Digestive System; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Patient Satisfaction; Propofol; Prospective Studies; Young Adult | 2015 |
Dexmedetomidine Does Not Affect Evoked Potentials During Spine Surgery.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Dexmedetomidine; Double-Blind Method; Evoked Potentials; Evoked Potentials, Motor; Evoked Potentials, Somatosensory; Evoked Potentials, Visual; Female; Humans; Hypnotics and Sedatives; Intraoperative Neurophysiological Monitoring; Male; Middle Aged; Orthopedic Procedures; Piperidines; Propofol; Reaction Time; Remifentanil; Spine; Time Factors | 2015 |
Comparison of the effects of propofol and emulsified isoflurane alone or combined with dexmedetomidine on induction of anesthesia in dogs.
Topics: Anesthesia; Anesthetics, Combined; Animals; Dexmedetomidine; Dogs; Isoflurane; Propofol; Prospective Studies | 2016 |
The effect of low-dose dexmedetomidine on hemodynamics and anesthetic requirement during bis-spectral index-guided total intravenous anesthesia.
Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthetics; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Carbon Dioxide; Cholecystectomy; Dexmedetomidine; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Piperidines; Pneumoperitoneum; Propofol; Remifentanil; Time Factors | 2016 |
Comparison of Dexmedetomidine versus Propofol for Sedation after Uvulopalatopharyngoplasty.
Topics: Adult; Conscious Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Palate, Soft; Pharynx; Postoperative Care; Propofol; Sleep Apnea, Obstructive; Uvula | 2015 |
Comparative Effects of Dexmedetomidine and Propofol on US-Guided Radiofrequency Ablation of Hepatic Neoplasm Under Monitored Anesthesia Care: A Randomized Controlled Study.
Topics: Analgesics; Catheter Ablation; Dexmedetomidine; Female; Hemodynamics; Humans; Liver Neoplasms; Male; Piperidines; Propofol; Remifentanil | 2015 |
Dexmedetomidine Improves Intubating Conditions Without Muscle Relaxants in Children After Induction With Propofol and Remifentanil.
Topics: Analgesics, Non-Narcotic; Anesthesia, General; Anesthetics, Intravenous; Child; Child, Preschool; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intubation, Intratracheal; Male; Muscle Relaxants, Central; Piperidines; Propofol; Remifentanil | 2015 |
A randomized, controlled trial to compare the efficacy and safety profile of a dexmedetomidine-ketamine combination with a propofol-fentanyl combination for ERCP.
Topics: Adolescent; Adult; Aged; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Bradycardia; Cholangiopancreatography, Endoscopic Retrograde; Deep Sedation; Dexmedetomidine; Female; Fentanyl; Humans; Hypnotics and Sedatives; Hypotension; Ketamine; Male; Middle Aged; Oxygen; Propofol; Prospective Studies; Young Adult | 2016 |
A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Delirium; Desflurane; Dexmedetomidine; Female; Humans; Isoflurane; Male; Propofol | 2016 |
[Effects of dexmedetomidine on propofol dosage in target-controlled infusion and hemodynamics during laparoscopic surgery under general anesthesia].
Topics: Anesthesia, General; Blood Pressure; Bradycardia; Dexmedetomidine; Heart Rate; Hemodynamics; Humans; Hypotension; Laparoscopy; Propofol | 2015 |
Dexmedetomidine versus Propofol Sedation Reduces Delirium after Cardiac Surgery: A Randomized Controlled Trial.
Topics: Aged; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Postoperative Complications; Propofol; Prospective Studies; Single-Blind Method | 2016 |
[Study of prevention and control of delirium in ventilated patients by simulating blockage of circadian rhythm with sedative in intensive care unit].
Topics: Analgesics; Circadian Rhythm; Critical Care; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Propofol; Prospective Studies; Respiration, Artificial | 2016 |
"ANESTHETIC SPARING EFFECT OF INTRAOPERATIVE LIGNOCAINE OR DEXMEDETOMIDINE INFUSION ON SEVOFLURANE DURING GENERAL ANESTHESIA".
Topics: Abdomen; Administration, Intravenous; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, General; Dexmedetomidine; Double-Blind Method; Female; Humans; Lidocaine; Male; Methyl Ethers; Middle Aged; Propofol; Prospective Studies; Sevoflurane; Young Adult | 2015 |
Intraoperative Dexmedetomidine Promotes Postoperative Analgesia and Recovery in Patients after Abdominal Hysterectomy: a Double-Blind, Randomized Clinical Trial.
Topics: Analgesia, Patient-Controlled; Anesthesia, General; Anesthetics, Intravenous; Dexmedetomidine; Double-Blind Method; Fatigue; Female; Humans; Hysterectomy; Intraoperative Care; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Piperidines; Propofol; Remifentanil; Surveys and Questionnaires | 2016 |
Comparison of sedation scores and propofol induction doses in dogs after intramuscular administration of dexmedetomidine alone or in combination with methadone, midazolam, or methadone plus midazolam.
Topics: Anesthetics, Combined; Animals; Conscious Sedation; Cross-Over Studies; Deep Sedation; Dexmedetomidine; Dogs; Female; Hypnotics and Sedatives; Male; Methadone; Midazolam; Propofol | 2016 |
Satisfaction and safety using dexmedetomidine or propofol sedation during endoscopic oesophageal procedures: A randomised controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Dexmedetomidine; Endoscopy; Esophagus; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Patient Safety; Patient Satisfaction; Propofol; Young Adult | 2016 |
Male patients require higher optimal effect-site concentrations of propofol during i-gel insertion with dexmedetomidine 0.5 μg/kg.
Topics: Adult; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Intubation, Intratracheal; Male; Middle Aged; Propofol; Sex Characteristics; Young Adult | 2016 |
Dexmedetomidine vs propofol-remifentanil conscious sedation for awake craniotomy: a prospective randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Brain Mapping; Conscious Sedation; Craniotomy; Dexmedetomidine; Double-Blind Method; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Patient Satisfaction; Piperidines; Propofol; Prospective Studies; Remifentanil; Respiratory Mechanics; Supratentorial Neoplasms; Wakefulness | 2016 |
Sex Differences in the Morphine-Sparing Effects of Intraoperative Dexmedetomidine in Patient-Controlled Analgesia Following General Anesthesia: A Consort-Prospective, Randomized, Controlled Clinical Trial.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, Intravenous; Dexmedetomidine; Female; Humans; Intraoperative Care; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Piperidines; Propofol; Remifentanil; Sex Factors | 2016 |
A comparative study between propofol and dexmedetomidine as sedative agents during performing transcatheter aortic valve implantation.
Topics: Aged; Blood Pressure; Dexmedetomidine; Female; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Pilot Projects; Propofol; Prospective Studies; Transcatheter Aortic Valve Replacement | 2016 |
[Effect of dexmedetomidine infusion on postoperative recovery for patients undergoing major spinal surgery during propofol anesthesia].
Topics: Adolescent; Adult; Aged; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intravenous; Dexmedetomidine; Heart Rate; Humans; Middle Aged; Morphine; Neurosurgical Procedures; Propofol; Sufentanil; Vomiting; Young Adult | 2016 |
[Clinical application of different sedation regimen in patients with septic shock].
Topics: Anesthesia; Conscious Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Male; Midazolam; Propofol; Respiration, Artificial; Shock, Septic; Time Factors; Treatment Outcome | 2016 |
Effects of dexmedetomidine and propofol on patient-ventilator interaction in difficult-to-wean, mechanically ventilated patients: a prospective, open-label, randomised, multicentre study.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Italy; Male; Middle Aged; Propofol; Prospective Studies; Respiration, Artificial; Ventilator Weaning | 2016 |
Effect of different doses of dexmedetomidine on median effective concentration of propofol for anesthesia induction: a randomized controlled trial.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Intravenous; Consciousness Monitors; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Hypnotics and Sedatives; Male; Propofol; Prospective Studies | 2016 |
Sedation with Dexmedetomidine or Propofol Impairs Hypoxic Control of Breathing in Healthy Male Volunteers: A Nonblinded, Randomized Crossover Study.
Topics: Adolescent; Adult; Cross-Over Studies; Dexmedetomidine; Humans; Hypercapnia; Hypnotics and Sedatives; Hypoxia; Male; Propofol; Reference Values; Respiration; Young Adult | 2016 |
Effects of Dexmedetomidine on motor- and somatosensory-evoked potentials in patients with thoracic spinal cord tumor: a randomized controlled trial.
Topics: Adult; Anesthetics, Intravenous; Consciousness Monitors; Dexmedetomidine; Evoked Potentials, Motor; Evoked Potentials, Somatosensory; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperidines; Propofol; Remifentanil; Spinal Cord Neoplasms; Thoracic Vertebrae | 2016 |
Effect of Continuous Paravertebral Dexmedetomidine Administration on Intraoperative Anesthetic Drug Requirement and Post-Thoracotomy Pain Syndrome After Thoracotomy: A Randomized Controlled Trial.
Topics: Adjuvants, Anesthesia; Adult; Aged; Amides; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Humans; Intraoperative Care; Middle Aged; Morphine; Nerve Block; Pain Measurement; Pain, Postoperative; Propofol; Ropivacaine; Syndrome; Thoracotomy; Young Adult | 2017 |
The effect of dexmedetomidine pretreatment on the median effective bolus dose of propofol for facilitating laryngeal mask airway insertion.
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Apnea; Dexmedetomidine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Laryngeal Masks; Lidocaine; Male; Middle Aged; Propofol | 2017 |
Comparing the efficacy and safety between propofol and dexmedetomidine for sedation in claustrophobic adults undergoing magnetic resonance imaging (PADAM trial).
Topics: Adult; Aged; Anxiety; Bradycardia; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Hypotension; Magnetic Resonance Imaging; Male; Middle Aged; Patient Satisfaction; Phobic Disorders; Propofol; Prospective Studies; Time Factors; Treatment Outcome | 2016 |
Effects of dexmedetomidine on the deformability of erythrocyte in patients with laparoscopic cholecystectomy.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Anesthetics, Intravenous; Blood Loss, Surgical; China; Cholecystectomy, Laparoscopic; Dexmedetomidine; Drug Administration Schedule; Erythrocyte Deformability; Female; Hematocrit; Humans; Infusions, Intravenous; Male; Middle Aged; Operative Time; Piperidines; Propofol; Remifentanil; Time Factors; Treatment Outcome | 2016 |
[Impact of dexmedetomidine-sevoflurane anesthesia on intraoperative wake-up test in children patients undergoing scoliosis surgery].
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Anesthesia, General; Arterial Pressure; Atracurium; Child; Child, Preschool; Dexmedetomidine; Double-Blind Method; Female; Heart Rate; Humans; Intraoperative Awareness; Intubation, Intratracheal; Male; Methyl Ethers; Midazolam; Piperidines; Propofol; Prospective Studies; Remifentanil; Scoliosis; Sevoflurane; Sufentanil | 2016 |
Comparison of the pro-postoperative analgesia of intraoperative dexmedetomidine with and without loading dose following general anesthesia: A prospective, randomized, controlled clinical trial.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anesthesia, General; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Intraoperative Period; Male; Middle Aged; Pain, Postoperative; Postoperative Period; Propofol; Prospective Studies | 2017 |
Combined use of dexmedetomidine and propofol in monitored anesthesia care: a randomized controlled study.
Topics: Airway Obstruction; Blood Pressure; Bradycardia; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypnotics and Sedatives; Hypoxia; Infusion Pumps; Male; Middle Aged; Oxygen; Patient Satisfaction; Propofol | 2017 |
The Effect of Sedation on Cortical Activation: A Randomized Study Comparing the Effects of Sedation With Midazolam, Propofol, and Dexmedetomidine on Auditory Processing.
Topics: Adult; Auditory Cortex; Auditory Perception; Conscious Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Injections, Intravenous; Magnetic Resonance Imaging; Male; Midazolam; Music; Propofol; Young Adult | 2017 |
Comparison of dexmedetomidine and propofol for conscious sedation in inguinal hernia repair: A prospective, randomized, controlled trial.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Conscious Sedation; Dexmedetomidine; Drug Combinations; Female; Fentanyl; Heart Rate; Hernia, Inguinal; Humans; Male; Middle Aged; Pain, Postoperative; Patient Satisfaction; Propofol; Prospective Studies | 2017 |
The effect of dexmedetomidine on cerebral perfusion and oxygenation in healthy piglets with normal and lowered blood pressure anaesthetized with propofol-remifentanil total intravenous anaesthesia.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Blood Pressure; Cerebrovascular Circulation; Dexmedetomidine; Drug Therapy, Combination; Female; Hypnotics and Sedatives; Monitoring, Intraoperative; Oxygen; Piperidines; Propofol; Remifentanil; Swine | 2017 |
Comparison of ketamine-propofol and ketamine-dexmedetomidine combinations in children for sedation during tooth extraction.
Topics: Anesthetics, Dissociative; Anxiety; Child; Child, Preschool; Deep Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Ketamine; Male; Pain, Postoperative; Postoperative Nausea and Vomiting; Propofol; Tooth Extraction | 2017 |
Propofol-dexmedetomidine versus propofol-remifentanil conscious sedation for awake craniotomy during epilepsy surgery.
Topics: Adolescent; Adult; Analgesics, Opioid; Conscious Sedation; Craniotomy; Dexmedetomidine; Double-Blind Method; Drug Combinations; Epilepsy; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol; Remifentanil; Wakefulness; Young Adult | 2017 |
Epidural Dexmedetomidine Reduces the Requirement of Propofol during Total Intravenous Anaesthesia and Improves Analgesia after Surgery in Patients undergoing Open Thoracic Surgery.
Topics: Aged; Analgesia, Epidural; Anesthesia, Intravenous; Dexmedetomidine; Female; Humans; Levobupivacaine; Male; Middle Aged; Pain, Postoperative; Propofol; Thoracic Surgical Procedures | 2017 |
Comparison of propofol and dexmedetomidine infused overnight to treat hyperactive and mixed ICU delirium: a protocol for the Basel ProDex clinical trial.
Topics: Critical Illness; Delirium; Dexmedetomidine; Electroencephalography; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Length of Stay; Propofol; Quality of Life; Research Design; Sleep; Switzerland; Time Factors | 2017 |
The relative effects of dexmedetomidine and propofol on cerebral blood flow velocity and regional brain oxygenation: A randomised noninferiority trial.
Topics: Aged; Blood Flow Velocity; Brain; Cerebrovascular Circulation; Dexmedetomidine; Electrodes, Implanted; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Oxygen Inhalation Therapy; Propofol; Spectroscopy, Near-Infrared; Treatment Outcome | 2017 |
Postinduction apnoea in dogs premedicated with acepromazine or dexmedetomidine and anaesthetized with alfaxalone or propofol.
Topics: Acepromazine; Anesthesia, General; Anesthetics, Combined; Animals; Apnea; Carbon Dioxide; Dexmedetomidine; Dogs; Female; Intubation, Intratracheal; Male; Preanesthetic Medication; Pregnanediones; Propofol; Respiratory Rate | 2017 |
Comparison of dexmedetomidine and fentanyl to prevent haemodynamic response to skull pin application in neurosurgery: double blind randomized controlled trial.
Topics: Adult; Anesthetics, Intravenous; Blood Pressure; Bone Nails; Craniotomy; Dexmedetomidine; Double-Blind Method; Female; Fentanyl; Heart Rate; Hemodynamics; Humans; Hypertension; Hypnotics and Sedatives; Hypotension; Male; Middle Aged; Neurosurgical Procedures; Propofol; Prospective Studies; Skull | 2017 |
Effect of dexmedetomidine on the minimum infusion rate of propofol preventing movement in dogs.
Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Cross-Over Studies; Dexmedetomidine; Dogs; Female; Hypnotics and Sedatives; Male; Movement; Propofol | 2017 |
Intraoperative administration of dexmedetomidine reduced the postoperative catheter-related bladder discomfort and pain in patients undergoing lumbar microdiscectomy.
Topics: Adult; Dexmedetomidine; Humans; Lumbar Vertebrae; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Postoperative Period; Propofol; Prospective Studies; Urinary Catheterization; Urinary Catheters | 2018 |
Effect of dexmedetomidine for attenuation of propofol injection pain in electroconvulsive therapy: a randomized controlled study.
Topics: Adolescent; Adult; Analgesics; Dexmedetomidine; Double-Blind Method; Electroconvulsive Therapy; Female; Humans; Hypnotics and Sedatives; Male; Pain; Pain Measurement; Propofol; Young Adult | 2018 |
A comparison between inhalational (Desflurane) and total intravenous anaesthesia (Propofol and dexmedetomidine) in improving postoperative recovery for morbidly obese patients undergoing laparoscopic sleeve gastrectomy: A double-blinded randomised control
Topics: Adult; Analgesics; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Desflurane; Dexmedetomidine; Double-Blind Method; Female; Gastrectomy; Humans; Laparoscopy; Male; Middle Aged; Obesity, Morbid; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Propofol; Prospective Studies; Treatment Outcome; Young Adult | 2018 |
Comparison of a loading dose of dexmedetomidine combined with propofol or sevoflurane for hemodynamic changes during anesthesia maintenance: a prospective, randomized, double-blind, controlled clinical trial.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Dexmedetomidine; Double-Blind Method; Female; Hemodynamics; Humans; Infusions, Intravenous; Male; Methyl Ethers; Middle Aged; Propofol; Sevoflurane | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Night Care; Placebo Effect; Propofol; Time Factors | 2018 |
Intraoperative Sedation With Dexmedetomidine is Superior to Propofol for Elderly Patients Undergoing Hip Arthroplasty: A Prospective Randomized Controlled Study.
Topics: Aged; Arthroplasty, Replacement, Hip; Cognitive Dysfunction; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Incidence; Male; Nerve Block; Postoperative Complications; Propofol; Treatment Outcome | 2018 |
Differentiating Drug-related and State-related Effects of Dexmedetomidine and Propofol on the Electroencephalogram.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Anesthetics, Intravenous; Dexmedetomidine; Electroencephalography; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Propofol; Young Adult | 2018 |
Dexmedetomidine for the reduction of emergence delirium in children undergoing tonsillectomy with propofol anesthesia: A double-blind, randomized study.
Topics: Adolescent; Anesthesia Recovery Period; Anesthetics, Intravenous; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Female; Humans; Hypnotics and Sedatives; Male; Propofol; Prospective Studies; Tonsillectomy; Treatment Outcome | 2018 |
Corticoadrenal and Cardiorespiratory Responses to Administration of Propofol Combined with Dexmedetomidine or Ketamine in Rabbits.
Topics: Adrenal Cortex; Anesthetics; Animals; Corticosterone; Dexmedetomidine; Drug Therapy, Combination; Female; Heart; Heart Rate; Hydrocortisone; Ketamine; Laboratory Animal Science; Propofol; Rabbits; Random Allocation; Respiratory Rate | 2018 |
The Effect of Dexmedetomidine on Propofol Requirements During Anesthesia Administered by Bispectral Index-Guided Closed-Loop Anesthesia Delivery System: A Randomized Controlled Study.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Anesthesia, Closed-Circuit; Anesthesia, Intravenous; Anesthetics, Intravenous; Consciousness Monitors; Dexmedetomidine; Double-Blind Method; Drug Interactions; Equipment Design; Female; Humans; India; Infusions, Intravenous; Intraoperative Neurophysiological Monitoring; Laparoscopy; Male; Middle Aged; Propofol; Prospective Studies; Robotic Surgical Procedures; Treatment Outcome; Young Adult | 2019 |
Intranasal Dexmedetomidine in Termination of First Trimester Pregnancy of Suction Evacuation.
Topics: Abortion, Induced; Administration, Intranasal; Adult; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Pregnancy; Pregnancy Trimester, First; Propofol; Vacuum Curettage | 2018 |
Effect of dexmedetomidine on intraocular pressure in patients undergoing robot-assisted laparoscopic radical prostatectomy under total intravenous anesthesia: A randomized, double blinded placebo controlled clinical trial.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Dexmedetomidine; Double-Blind Method; Head-Down Tilt; Humans; Intraocular Pressure; Laparoscopy; Male; Middle Aged; Ocular Hypertension; Patient Positioning; Placebos; Pneumoperitoneum, Artificial; Propofol; Prospective Studies; Prostatectomy; Robotic Surgical Procedures; Tonometry, Ocular; Treatment Outcome | 2018 |
Different effects of propofol and dexmedetomidine sedation on electroencephalogram patterns: Wakefulness, moderate sedation, deep sedation and recovery.
Topics: Acoustic Stimulation; Adult; Brain Mapping; Brain Waves; Conscious Sedation; Consciousness Monitors; Cross-Over Studies; Deep Sedation; Dexmedetomidine; Electroencephalography; Humans; Hypnotics and Sedatives; Male; Propofol; Wakefulness; Young Adult | 2018 |
Dexmedetomidine and intravenous acetaminophen for the prevention of postoperative delirium following cardiac surgery (DEXACET trial): protocol for a prospective randomized controlled trial.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Boston; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cognition; Coronary Artery Bypass; Delirium; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Heart Valve Prosthesis Implantation; Humans; Hypnotics and Sedatives; Length of Stay; Propofol; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Time Factors; Treatment Outcome | 2018 |
Spoken words are processed during dexmedetomidine-induced unresponsiveness.
Topics: Acoustic Stimulation; Adult; Deep Sedation; Dexmedetomidine; Discrimination, Psychological; Electroencephalography; Evoked Potentials; Humans; Hypnotics and Sedatives; Male; Memory; Perception; Propofol; Psychomotor Performance; Recognition, Psychology; Young Adult | 2018 |
Comparative effects of dexmedetomidine, propofol, sevoflurane, and S-ketamine on regional cerebral glucose metabolism in humans: a positron emission tomography study.
Topics: Adolescent; Adult; Anesthetics, Dissociative; Anesthetics, Inhalation; Brain; Brain Chemistry; Cerebrovascular Circulation; Dexmedetomidine; Fluorodeoxyglucose F18; Glucose; Humans; Hypnotics and Sedatives; Ketamine; Kinetics; Male; Positron-Emission Tomography; Propofol; Radiopharmaceuticals; Sevoflurane; Young Adult | 2018 |
[Effect of dexmedetomidine combined with sevoflurane for general anesthesia during dental treatment in pediatric patients].
Topics: Anesthesia, General; Child; Dental Care; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol; Prospective Studies; Sevoflurane | 2018 |
Dexmedetomidine and Midazolam Sedation Reduces Unexpected Patient Movement During Dental Surgery Compared With Propofol and Midazolam Sedation.
Topics: Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Propofol; Prospective Studies | 2019 |
Impact of Dexmedetomidine on Intraoperative Wake-Up Tests in Patients Undergoing Spinal Surgery.
Topics: Adult; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intraoperative Period; Male; Middle Aged; Propofol; Remifentanil; Spinal Diseases; Wakefulness | 2018 |
Comparison of upper airway patency in patients with mild obstructive sleep apnea during dexmedetomidine or propofol sedation: a prospective, randomized, controlled trial.
Topics: Adult; Aged; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Oximetry; Propofol; Prospective Studies; Retrospective Studies; Sleep Apnea, Obstructive; Tidal Volume | 2018 |
The Effect of Propofol and Dexmedetomidine Sedation on Norepinephrine Requirements in Septic Shock Patients: A Crossover Trial.
Topics: Acid-Base Equilibrium; Adrenergic alpha-Agonists; Cross-Over Studies; Deep Sedation; Dexmedetomidine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Norepinephrine; Propofol; Shock, Septic | 2019 |
Effects of dexmedetomidine, propofol and etomidate on the intraoperative wake-up in the cerebral functional area under the guidance of entropy index.
Topics: Adult; Anesthetics, Intravenous; Brain; Dexmedetomidine; Entropy; Etomidate; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Neurosurgical Procedures; Propofol; Remifentanil; Wakefulness | 2018 |
Effect of dexmedetomidine or propofol sedation on haemodynamic stability of patients after thoracic surgery.
Topics: Adult; Anesthesia Recovery Period; Conscious Sedation; Dexmedetomidine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Postoperative Care; Propofol; Thoracic Surgical Procedures | 2018 |
Sedative effect of dexmedetomidine in spinal-epidural anesthesia on hysteromyomectomy.
Topics: Administration, Intravenous; Adult; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Consciousness; Dexmedetomidine; Female; Heart Rate; Humans; Hypnotics and Sedatives; Injections, Spinal; Lidocaine; Middle Aged; Propofol; Ropivacaine; Time Factors; Uterine Myomectomy | 2018 |
Comparison of sedation with dexmedetomidine vs propofol during hysteroscopic surgery: Single-centre randomized controlled trial.
Topics: Adult; Arterial Pressure; Conscious Sedation; Dexmedetomidine; Female; Heart Rate; Humans; Hypnotics and Sedatives; Hysteroscopy; Middle Aged; Pain, Postoperative; Propofol | 2019 |
Effects of propofol, dexmedetomidine, and midazolam on postoperative cognitive dysfunction in elderly patients: a randomized controlled preliminary trial.
Topics: Aged; Cognitive Dysfunction; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Neuropsychological Tests; Postoperative Complications; Propofol; Prospective Studies | 2019 |
Effect of Intravenous Acetaminophen vs Placebo Combined With Propofol or Dexmedetomidine on Postoperative Delirium Among Older Patients Following Cardiac Surgery: The DEXACET Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Incidence; Length of Stay; Male; Middle Aged; Postoperative Complications; Propofol | 2019 |
Dexmedetomidine versus propofol at different sedation depths during drug-induced sleep endoscopy: A randomized trial.
Topics: Adolescent; Adult; Aged; Deep Sedation; Dexmedetomidine; Endoscopy; Female; Heart Function Tests; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol; Prospective Studies; Respiratory Function Tests; Single-Blind Method; Young Adult | 2020 |
Effect of perioperative administration of dexmedetomidine on delirium after cardiac surgery in elderly patients: a double-blinded, multi-center, randomized study.
Topics: Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Postoperative Period; Propofol; Time Factors | 2019 |
[Effect of Dexmedetomidine Combined with Propofol or Sevoflurane General Anesthesia on Stress and Postoperative Quality of Recovery(QoR-40) in Patients Undergoing Laparoscopic Surgery].
Topics: Anesthesia, General; Dexmedetomidine; Humans; Laparoscopy; Methyl Ethers; Propofol; Sevoflurane | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Hypotension; Intensive Care Units; Intention to Treat Analysis; Male; Midazolam; Middle Aged; Propofol; Respiration, Artificial; Time Factors; Treatment Outcome | 2019 |
The safety and efficacy of dexmedetomidine versus propofol for patients undergoing endovascular therapy for acute stroke: A prospective randomized control trial.
Topics: Aged; Anesthesia Recovery Period; Dexmedetomidine; Endovascular Procedures; Female; Fibrinolytic Agents; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Postoperative Complications; Propofol; Prospective Studies; Stroke; Vasoconstrictor Agents | 2019 |
Comparing the effect of dexmedetomidine and labetalol on hemodynamic variables in patients undergoing microlaryngoscopy.
Topics: Adrenergic beta-Antagonists; Adult; Analgesics, Non-Narcotic; Blood Pressure; Dexmedetomidine; Double-Blind Method; Female; Heart Rate; Humans; Labetalol; Laryngoscopy; Male; Microsurgery; Middle Aged; Propofol | 2019 |
Discharge Readiness after Propofol with or without Dexmedetomidine for Colonoscopy: A Randomized Controlled Trial.
Topics: Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Arterial Pressure; Blood Pressure; Colonoscopy; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Patient Discharge; Propofol; Prospective Studies; Time Factors | 2019 |
Dexmedetomidine vs propofol as sedation for implantation of neurostimulators: A single-center single-blinded randomized controlled trial.
Topics: Adult; Conscious Sedation; Dexmedetomidine; Female; Hemodynamics; Humans; Implantable Neurostimulators; Male; Middle Aged; Patient Satisfaction; Propofol; Single-Blind Method; Time Factors | 2019 |
Efficacy and Tolerability of Sufentanil, Dexmedetomidine, or Ketamine Added to Propofol-based Sedation for Gastrointestinal Endoscopy in Elderly Patients: A Prospective, Randomized, Controlled Trial.
Topics: Aged; Anesthesia; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Female; Humans; Hypnotics and Sedatives; Ketamine; Male; Propofol; Sufentanil; Treatment Outcome | 2019 |
Upper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover Study.
Topics: Adult; Aged; Airway Obstruction; Cross-Over Studies; Dexmedetomidine; Female; Healthy Volunteers; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pharynx; Propofol; Young Adult | 2019 |
Does Including Dexmedetomidine Improve Outcomes After Intravenous Sedation for Outpatient Dentoalveolar Surgery?
Topics: Anesthesia; Dexmedetomidine; Humans; Hypnotics and Sedatives; Outpatients; Propofol; Prospective Studies | 2020 |
Effects of dexmedetomidine on post-operative recovery and mental status in patients receiving robotic-assisted thoracic surgery.
Topics: Adjuvants, Anesthesia; Adult; Aged; Dexmedetomidine; Female; Health Status; Humans; Hypnotics and Sedatives; Male; Mental Disorders; Midazolam; Middle Aged; Postoperative Complications; Propofol; Respiration, Artificial; Robotic Surgical Procedures; Rocuronium; Sufentanil; Thoracic Surgical Procedures; Young Adult | 2019 |
Respiratory and hemodynamic effects of three different sedative regimens for drug induced sleep endoscopy in sleep apnea patients. A prospective randomized study.
Topics: Adult; Anesthesia Recovery Period; Blood Pressure; Dexmedetomidine; Endoscopy; Female; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Oxygen; Propofol; Prospective Studies; Psychoses, Substance-Induced; Respiratory Mechanics; Sleep; Sleep Apnea, Obstructive | 2020 |
The Benefit of Dexmedetomidine on Postoperative Cognitive Function Is Unrelated to the Modulation on Peripheral Inflammation: A Single-center, Prospective, Randomized Study.
Topics: Aged; Analgesics, Non-Narcotic; Arthroplasty, Replacement, Knee; Cognition; Dexmedetomidine; Humans; Inflammation; Postoperative Complications; Propofol; Prospective Studies | 2020 |
Comparison of Intraoperative Sedation With Dexmedetomidine Versus Propofol on Acute Postoperative Pain in Total Knee Arthroplasty Under Spinal Anesthesia: A Randomized Trial.
Topics: Acute Pain; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Intravenous; Arthroplasty, Replacement, Knee; Dexmedetomidine; Female; Fentanyl; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Propofol; Republic of Korea; Time Factors; Treatment Outcome; Young Adult | 2019 |
The influence of dexmedetomidine and propofol on circulating cytokine levels in healthy subjects.
Topics: Adult; Anesthetics, Intravenous; Chemokines; Cytokines; Dexmedetomidine; Dose-Response Relationship, Drug; Humans; Hypnotics and Sedatives; Male; Propofol; Young Adult | 2019 |
The effects of different doses of dexmedetomidine on the requirements for propofol for loss of consciousness in patients monitored via the bispectral index: a double-blind, placebo-controlled trial.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Anesthesia, General; Consciousness Monitors; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol; Prospective Studies | 2020 |
Dexmedetomidine versus propofol for prolonged sedation in critically ill trauma and surgical patients.
Topics: Adolescent; Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Prospective Studies | 2021 |
Dexmedetomidine Provides Fewer Respiratory Events Compared With Propofol and Fentanyl During Third Molar Surgery: A Randomized Clinical Trial.
Topics: Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Molar, Third; Propofol; Prospective Studies | 2020 |
Effects of spinal anesthesia and sedation with dexmedetomidine or propofol on cerebral regional oxygen saturation and systemic oxygenation a period after spinal injection.
Topics: Anesthesia, Spinal; Dexmedetomidine; Humans; Hypnotics and Sedatives; Injections, Spinal; Oxygen; Propofol | 2020 |
The synergistic effect of dexmedetomidine on propofol for paediatric deep sedation: A randomised trial.
Topics: Adult; Child; Deep Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol; Prospective Studies | 2021 |
Dexmedetomidine-remifentanil vs propofol-remifentanil for monitored anesthesia care during hysteroscopy: Randomized, single-blind, controlled trial.
Topics: Adult; Analgesics, Opioid; Anesthetics, Intravenous; Dexmedetomidine; Drug Combinations; Female; Humans; Hypnotics and Sedatives; Hysteroscopy; Middle Aged; Monitoring, Intraoperative; Propofol; Remifentanil; Single-Blind Method | 2020 |
Effect of dexmedetomidine on Nociception Level Index-guided remifentanil antinociception: A randomised controlled trial.
Topics: Anesthetics, Intravenous; Belgium; Dexmedetomidine; Humans; Nociception; Propofol; Remifentanil | 2021 |
Effects of Propofol, Dexmedetomidine, or Ketofol on Respiratory and Hemodynamic Profiles in Cardiac Patients Undergoing Transesophageal Echocardiography: A Prospective Randomized Study.
Topics: Conscious Sedation; Dexmedetomidine; Echocardiography, Transesophageal; Hemodynamics; Humans; Hypnotics and Sedatives; Propofol; Prospective Studies | 2021 |
Comparison of dexmedetomidine-propofol and ketamine-propofol administration during sedation-guided upper gastrointestinal system endoscopy.
Topics: Adolescent; Adult; Blood Pressure; Dexmedetomidine; Drug Combinations; Endoscopy, Digestive System; Female; Humans; Hypnotics and Sedatives; Ketamine; Male; Middle Aged; Propofol; Young Adult | 2020 |
Propofol plus low-dose dexmedetomidine infusion and postoperative delirium in older patients undergoing cardiac surgery.
Topics: Aged; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Postoperative Complications; Propofol; Treatment Outcome | 2021 |
Efficacy of sedation with dexmedetomidine plus propofol during esophageal endoscopic submucosal dissection.
Topics: Conscious Sedation; Dexmedetomidine; Endoscopic Mucosal Resection; Esophageal Neoplasms; Humans; Hypnotics and Sedatives; Propofol; Prospective Studies; Psychomotor Agitation | 2021 |
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.
Topics: Adult; Cognition; Conscious Sedation; Critical Illness; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Kaplan-Meier Estimate; Propofol; Respiration, Artificial; Sepsis | 2021 |
Low-Dose Dexmedetomidine Reduces Median Effective Concentration (EC 50) of Propofol More than Fentanyl in Unparalysed Anaesthetised Patients for I-gel Insertion: a Randomised Controlled Trial.
Topics: Adult; Anesthetics, Intravenous; Dexmedetomidine; Dose-Response Relationship, Drug; Fentanyl; Humans; Middle Aged; Propofol; Young Adult | 2021 |
Effect of dexmedetomidine on evoked-potential monitoring in patients undergoing brain stem and supratentorial cranial surgery.
Topics: Brain Stem; Dexmedetomidine; Double-Blind Method; Evoked Potentials, Somatosensory; Humans; Propofol; Prospective Studies; Remifentanil | 2021 |
A comparative study of dexmedetomidine and propofol to prevent recovery agitation in adults undergoing procedural sedation with ketamine: A randomized double-blind clinical trial.
Topics: Adult; Anesthetics, Dissociative; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Emergency Service, Hospital; Female; Humans; Hypnotics and Sedatives; Iran; Ketamine; Male; Pain Measurement; Propofol; Prospective Studies; Psychomotor Agitation | 2021 |
Effects of dexmedetomidine, propofol, sevoflurane and S-ketamine on the human metabolome: A randomised trial using nuclear magnetic resonance spectroscopy.
Topics: Amino Acids; Anesthetics, Inhalation; Dexmedetomidine; Fatty Acids; Glucose; Glycerides; Humans; Ketamine; Ketone Bodies; Magnetic Resonance Spectroscopy; Male; Metabolome; Methyl Ethers; Phospholipids; Propofol; Sevoflurane | 2022 |
Analysis on the effect of intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides on hemodynamics and analgesia in pregnant females undergoing painless induced abortion.
Topics: Abortion, Induced; Adult; Anesthetics, Intravenous; Arterial Pressure; Carrageenan; Deep Sedation; Dexmedetomidine; Dizziness; Female; Heart Rate; Hemodynamics; Humans; Pain, Procedural; Postoperative Complications; Postoperative Nausea and Vomiting; Pregnancy; Propofol; Seaweed; Sufentanil; Young Adult | 2021 |
Cardiopulmonary effects and recovery characteristics associated with 2 sedative protocols for assisted ventilation in healthy neonatal foals.
Topics: Anesthesia Recovery Period; Animals; Animals, Newborn; Butorphanol; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Rate; Horses; Hypnotics and Sedatives; Male; Midazolam; Propofol; Respiration, Artificial; Respiratory Physiological Phenomena | 2021 |
Comparing the Efficacy and Safety of Dexmedetomidine/Ketamine with Propofol/Fentanyl for Sedation in Colonoscopy Patients: A Doubleblinded Randomized Clinical Trial.
Topics: Apnea; Colonoscopy; Dexmedetomidine; Double-Blind Method; Fentanyl; Humans; Hypnotics and Sedatives; Hypotension; Ketamine; Pain; Propofol; Prospective Studies | 2022 |
Effect of administering dexmedetomidine with or without atropine on cardiac troponin I level in isoflurane-anesthetized dogs.
Topics: Animals; Atropine; Dexmedetomidine; Dogs; Isoflurane; Propofol; Troponin I | 2021 |
Effect of remimazolam besylate compared with propofol on the incidence of delirium after cardiac surgery: study protocol for a randomized trial.
Topics: Benzodiazepines; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Incidence; Propofol; Prospective Studies; Randomized Controlled Trials as Topic | 2021 |
Comparison of the hemodynamic response of dexmedetomidine versus additional intravenous lidocaine with propofol during tracheal intubation: a randomized controlled study.
Topics: Administration, Intravenous; Adult; Anesthesia, General; Blood Pressure; Dexmedetomidine; Elective Surgical Procedures; Female; Heart Rate; Humans; Intubation, Intratracheal; Laryngoscopy; Lidocaine; Male; Middle Aged; Propofol; Prospective Studies | 2021 |
Comparison of Intra and Post-operative Sedation Efficacy of Dexmedetomidinemidazolam and Dexmedetomidine-propofol for Major Abdominal Surgery.
Topics: Anesthesia; Apnea; Dexmedetomidine; Humans; Hypertension; Hypnotics and Sedatives; Hypotension; Hypoxia; Midazolam; Propofol; Prospective Studies | 2022 |
Comparing the effects of dexmedetomidine versus propofol on the treatment of emergence agitation in adult patients after general anesthesia: study protocol for a randomized, superiority, controlled trial (DP-TEA Trial).
Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Dexmedetomidine; Emergence Delirium; Female; Humans; Male; Propofol; Randomized Controlled Trials as Topic | 2021 |
Dexmedetomidine Use in Intensive Care Unit Sedation and Postoperative Recovery in Elderly Patients Post-Cardiac Surgery (DIRECT).
Topics: Aged; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Quality of Life | 2022 |
Single bolus dexmedetomidine versus propofol for treatment of pediatric emergence delirium following general anesthesia.
Topics: Anesthesia Recovery Period; Anesthesia, General; Child; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Humans; Hypnotics and Sedatives; Propofol; Prospective Studies | 2022 |
Intraoperative effect of low doses of ketamine or dexmedetomidine continuous rate infusions in healthy dogs receiving propofol total intravenous anaesthesia and epidural anaesthesia: A prospective, randomised clinical study.
Topics: Anesthesia, Epidural; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Dexmedetomidine; Dogs; Ketamine; Propofol; Prospective Studies | 2022 |
Dexmedetomidine versus propofol for operator-directed nurse-administered procedural sedation during catheter ablation of atrial fibrillation: A randomized controlled study.
Topics: Atrial Fibrillation; Catheter Ablation; Dexmedetomidine; Humans; Hypercapnia; Hypnotics and Sedatives; Propofol | 2022 |
Safety and Efficacy of IV Dexmedetomidine as an Adjunct to Propofol to Sedate Anxious and Uncooperative Pediatric Dental Patients: A Randomized Controlled Trial.
Topics: Child; Child, Preschool; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Oxygen Saturation; Propofol | 2021 |
Combined opioid free and loco-regional anaesthesia enhances the quality of recovery in sleeve gastrectomy done under ERAS protocol: a randomized controlled trial.
Topics: Adult; Anesthesia, Conduction; Anesthesia, Local; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Local; Atracurium; Dexmedetomidine; Enhanced Recovery After Surgery; Female; Fentanyl; Gastrectomy; Humans; Hypnotics and Sedatives; Ketamine; Lidocaine; Male; Nerve Block; Neuromuscular Blocking Agents; Pain Management; Pain, Postoperative; Propofol; Young Adult | 2022 |
Clinical Efficacy of Perioperative Intravenous Dexmedetomidine and Lidocaine Combined Infusion for Thyroidectomy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Humans; Infusions, Intravenous; Lidocaine; Pain, Postoperative; Postoperative Nausea and Vomiting; Propofol; Prospective Studies; Thyroidectomy; Treatment Outcome | 2022 |
Restoration Algorithm-Based Ultrasound Image in Evaluating the Effect of Dexmedetomidine on Patients with Neurological Disorder Anesthetized by Sevoflurane.
Topics: Adult; Algorithms; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Blood Flow Velocity; Carotid Artery, Internal; Computational Biology; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Image Enhancement; Male; Middle Aged; Nervous System Diseases; Propofol; Sevoflurane; Tonsillectomy; Ultrasonography; Vertebral Artery | 2022 |
The effects of remifentanil-propofol combined with dexmedetomidine on cognitive dysfunction in elderly patients after ureteroscopic holmium laser lithotripsy: a double-blind randomized controlled trial.
Topics: Aged; Cognitive Dysfunction; Dexmedetomidine; Double-Blind Method; Holmium; Humans; Lithotripsy, Laser; Propofol; Remifentanil; Ureteroscopy | 2022 |
Dexmedetomidine versus propofol sedation in flexible bronchoscopy: a randomized controlled trial.
Topics: Bronchoscopy; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol | 2022 |
Effectiveness of single loading dose of dexmedetomidine combined with propofol for deep sedation of endoscopic retrograde cholangiopancreatography (ERCP) in elderly patients: a prospective randomized study.
Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Deep Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol; Prospective Studies | 2022 |
A double-blind randomized controlled trial to compare the safety and efficacy of dexmedetomidine alone and in combination with ketamine in uncooperative and anxious paediatric dental patients requiring pulpectomy.
Topics: Child; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Ketamine; Propofol; Pulpectomy | 2022 |
Dexmedetomidine dosage in critically ill patients undergoing intraoperative wake-up test: A randomized controlled trial.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Propofol; Remifentanil; Scoliosis | 2022 |
Comparison of Hemodynamics and Opioid Sparing Effect of Dexmedetomidine Nebulization and Intravenous Dexmedetomidine in Laparoscopic Surgeries Under General Anesthesia.
Topics: Analgesics, Opioid; Anesthesia, General; Dexmedetomidine; Fentanyl; Hemodynamics; Humans; Laparoscopy; Propofol; Prospective Studies; Saline Solution | 2022 |
Comparison of the efficacy and safety of sedation protocols with the use of dexmedetomidine-remifentanil and propofol-remifentanil during percutaneous closure of atrial septal defects: a randomized clinical trial.
Topics: Clinical Protocols; Dexmedetomidine; Drug Combinations; Heart Septal Defects, Atrial; Humans; Hypercapnia; Hypnotics and Sedatives; Pain; Propofol; Remifentanil; Treatment Outcome | 2022 |
Sequential use of midazolam and dexmedetomidine for long-term sedation may reduce weaning time in selected critically ill, mechanically ventilated patients: a randomized controlled study.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Propofol; Respiration, Artificial | 2022 |
Effect of Preventive Analgesia with Nalbuphine and Dexmedetomidine in Endoscopic Sinus Surgery.
Topics: Analgesia; Dexmedetomidine; Double-Blind Method; Humans; Nalbuphine; Piperidines; Propofol; Remifentanil | 2022 |
Effects of etomidate combined with dexmedetomidine on adrenocortical function in elderly patients: a double-blind randomized controlled trial.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Age Factors; Aged; Anesthetics, Intravenous; Dexmedetomidine; Double-Blind Method; Etomidate; Humans; Hydrocortisone; Propofol; Remifentanil | 2022 |
Sedative and cardiopulmonary effects of intramuscular combinations of hydromorphone, acepromazine, dexmedetomidine, and glycopyrrolate followed by intravenous propofol and inhalant isoflurane anesthesia in healthy dogs.
Topics: Acepromazine; Anesthesia; Anesthetics; Animals; Cross-Over Studies; Dexmedetomidine; Dogs; Female; Glycopyrrolate; Heart Rate; Hydromorphone; Hypnotics and Sedatives; Isoflurane; Propofol | 2022 |
The efficacy and safety of an adapted opioid-free anesthesia regimen versus conventional general anesthesia in gynecological surgery for low-resource settings: a randomized pilot study.
Topics: Analgesics, Opioid; Anesthesia, General; Clonidine; Dexamethasone; Dexmedetomidine; Diazepam; Female; Fentanyl; Gynecologic Surgical Procedures; Humans; Isoflurane; Ketamine; Lidocaine; Magnesium Sulfate; Pain, Postoperative; Pilot Projects; Propofol; Rocuronium; Saline Solution | 2022 |
Dexmedetomidine decreases the 50% effective dose (ED50) of intravenous propofol required to prevent tracheal intubation response in Beagles.
Topics: Animals; Dexmedetomidine; Dogs; Heart Rate; Hypnotics and Sedatives; Intubation, Intratracheal; Male; Propofol | 2022 |
Clinical effects of remimazolam alone or in combination with dexmedetomidine in patients receiving bronchoscopy and influences on postoperative cognitive function: a randomized-controlled trial.
Topics: Bronchoscopy; Cognition; Dexmedetomidine; Humans; Hypnotics and Sedatives; Hypoxia; Propofol | 2023 |
Effect of esketamine vs dexmedetomidine adjunct to propofol sedation for pediatric 3Tesla magnetic resonance imaging: a randomized, double-blind, controlled trial.
Topics: Child; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Propofol | 2022 |
Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Prospective Studies; Respiration, Artificial; Sepsis | 2022 |
Effect of different doses of dexmedetomidine on the median effective concentration of propofol during gastrointestinal endoscopy: a randomized controlled trial.
Topics: Adult; Anesthesia; Dexmedetomidine; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedatives; Propofol | 2023 |
Postoperative Delirium after Dexmedetomidine versus Propofol Sedation in Healthy Older Adults Undergoing Orthopedic Lower Limb Surgery with Spinal Anesthesia: A Randomized Controlled Trial.
Topics: Aged; Anesthesia, Spinal; Delirium; Dexmedetomidine; Emergence Delirium; Humans; Hypnotics and Sedatives; Lower Extremity; Propofol | 2023 |
Ketamine and dexmedetomidine (Keto-dex) or ketamine and propofol (Keto-fol) for procedural sedation during endoscopic retrograde cholangiopancreatography: Which is safer? A randomized clinical trial.
Topics: Adolescent; Adult; Aged; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Ketamine; Middle Aged; Pain; Propofol; Prospective Studies; Young Adult | 2022 |
Analysis of anesthetic effect of dexmedetomidine in femoral shaft fracture surgery.
Topics: Anesthesia, General; Anesthetics; Child; Dexmedetomidine; Emergence Delirium; Humans; Propofol | 2022 |
Dexmedetomidine as an adjuvant to scalp block in patients undergoing elective craniotomy: A prospective randomized controlled trial.
Topics: Craniotomy; Dexmedetomidine; Fentanyl; Humans; Pain, Postoperative; Propofol; Prospective Studies; Remifentanil; Ropivacaine; Scalp | 2023 |
Etomidate-ketamine versus dexmedetomidine-ketamine for entropy-guided procedural sedation during endoscopic retrograde cholangiopancreatography procedures: A randomized single blind study.
Topics: Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Dexmedetomidine; Entropy; Etomidate; Humans; Hypnotics and Sedatives; Ketamine; Propofol; Prospective Studies; Single-Blind Method | 2023 |
Examination of ADRB2 gene expression and influence of Dexmedetomidine and Propofol on Hemodynamics after Abdominal Surgery.
Topics: Dexmedetomidine; Gene Expression; Heart Rate; Hemodynamics; Humans; Propofol; Receptors, Adrenergic, beta-2 | 2023 |
Comparison of Procedural Sedation With Propofol and Dexmedetomidine During Transcatheter Aortic Valve Replacement Using the Transfemoral Approach.
Topics: Anesthesia; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol; Prospective Studies; Transcatheter Aortic Valve Replacement | 2023 |
Comparison of the perfusion index as an index of noxious stimulation in monitored anesthesia care of propofol/remifentanil and propofol/dexmedetomidine: a prospective, randomized, case-control, observational study.
Topics: Adult; Anesthesia; Case-Control Studies; Dexmedetomidine; Humans; Perfusion Index; Propofol; Prospective Studies; Remifentanil | 2023 |
Subjective experiences during dexmedetomidine- or propofol-induced unresponsiveness and non-rapid eye movement sleep in healthy male subjects.
Topics: Anesthetics; Dexmedetomidine; Eye Movements; Humans; Hypnotics and Sedatives; Male; Propofol; Sleep | 2023 |
Application of Dexmedetomidine in Surgical Anesthesia for Gastric Cancer and Its Effects on IL-1β, IL-6, TNF-α and CRP.
Topics: Anesthesia; Anesthetics, Intravenous; Dexmedetomidine; Humans; Interleukin-6; Propofol; Remifentanil; Stomach Neoplasms; Tumor Necrosis Factor-alpha | 2023 |
Prospective, randomised comparison of two intravenous sedation methods for magnetic resonance imaging in children.
Topics: Anesthesia; Anesthesia, Intravenous; Child; Dexmedetomidine; Humans; Hypnotics and Sedatives; Ketamine; Magnetic Resonance Imaging; Midazolam; Propofol; Prospective Studies | 2023 |
Prospective, randomized, double-blind, double-dummy, active-controlled, phase 3 clinical trial comparing the safety and efficacy of intranasal dexmedetomidine to oral midazolam as premedication for propofol sedation in pediatric patients undergoing magnet
Topics: Administration, Intranasal; Anesthesia; Child; Child, Preschool; Dexmedetomidine; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Midazolam; Premedication; Propofol; Prospective Studies | 2023 |
Comparison of the effects of dexmedetomidine and propofol on the cardiovascular autonomic nervous system during spinal anesthesia: preliminary randomized controlled observational study.
Topics: Anesthesia, Spinal; Autonomic Nervous System; Dexmedetomidine; Humans; Hypertension; Hypnotics and Sedatives; Propofol | 2023 |
Dexmedetomidine vs. propofol sedation reduces the duration of mechanical ventilation after cardiac surgery - a randomized controlled trial.
Topics: Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Propofol; Respiration, Artificial | 2023 |
Initial loading of dexmedetomidine and continuous propofol sedation for prevention of delayed recovery: A randomized controlled trial.
Topics: Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Propofol; Prospective Studies | 2023 |
Remimazolam besylate versus propofol for deep sedation in critically ill patients: a randomized pilot study.
Topics: Critical Illness; Deep Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Pilot Projects; Propofol; Prospective Studies; Respiration, Artificial | 2023 |
306 other study(ies) available for dexmedetomidine and propofol
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Comparison of medetomidine and dexmedetomidine as premedicants in dogs undergoing propofol-isoflurane anesthesia.
Topics: Adrenergic alpha-Agonists; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Pressure; Dexmedetomidine; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hypnotics and Sedatives; Isoflurane; Male; Medetomidine; Preanesthetic Medication; Propofol; Respiration; Stereoisomerism | 2001 |
Dexmedetomidine infusion and somatosensory evoked potentials.
Topics: Adrenergic alpha-Agonists; Aged; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Dexmedetomidine; Evoked Potentials, Somatosensory; Female; Humans; Laminectomy; Middle Aged; Monitoring, Intraoperative; Neurosurgical Procedures; Nitrous Oxide; Propofol | 2001 |
Difficult extubation: calming the sympathetic storm.
Topics: Aged; Conscious Sedation; Device Removal; Dexmedetomidine; Humans; Hypertension; Hypnotics and Sedatives; Intubation, Intratracheal; Male; Myocardial Infarction; Propofol; Pulmonary Edema; Stress, Physiological; Sympathetic Nervous System; Tachycardia; Ventricular Dysfunction, Left | 2004 |
Dexmedetomidine as the primary sedative agent for brain radiation therapy in a 21-month old child.
Topics: Brain Neoplasms; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant; Male; Propofol; Radiotherapy; Respiratory Mechanics; Rhabdoid Tumor | 2005 |
The prevention of pain from injection of propofol by dexmedetomidine and comparison with lidocaine.
Topics: Dexmedetomidine; Humans; Injections, Intravenous; Lidocaine; Pain; Propofol | 2005 |
"If you cannot measure it, you cannot improve it".
Topics: Conscious Sedation; Critical Care; Dexmedetomidine; Humans; Hypnotics and Sedatives; Patient Satisfaction; Propofol; Respiration, Artificial | 2005 |
Medications to provide cooperation in the critically ill pediatric patient: a rose with a thorn.
Topics: Adrenergic alpha-Agonists; Adult; Child; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol; Substance Withdrawal Syndrome | 2005 |
Dexmedetomidine for awake craniotomy without laryngeal mask.
Topics: Adult; Anesthetics, Combined; Conscious Sedation; Craniotomy; Dexmedetomidine; Epilepsy; Female; Fentanyl; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Propofol; Wakefulness | 2005 |
Use of dexmedetomidine in awake craniotomy in adolescents: report of two cases.
Topics: Adolescent; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Brain Mapping; Brain Neoplasms; Conscious Sedation; Craniotomy; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Oligodendroglioma; Propofol; Seizures; Wakefulness | 2006 |
Differential effects of intravenous anesthetics on ciliary motility in cultured rat tracheal epithelial cells.
Topics: Analgesics; Anesthetics, Intravenous; Animals; Cells, Cultured; Cilia; Dexmedetomidine; Epithelial Cells; Fentanyl; Hypnotics and Sedatives; In Vitro Techniques; Ketamine; Male; Midazolam; Motion; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Thiopental; Time Factors; Trachea | 2006 |
Addition of dexmedetomidine to standard sedation regimens after cardiac surgery: an outcomes analysis.
Topics: Aged; Cardiac Surgical Procedures; Dexmedetomidine; Drug Therapy, Combination; Female; Hospitals; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Lorazepam; Male; Midazolam; Middle Aged; Outcome Assessment, Health Care; Propofol; Retrospective Studies | 2006 |
Propofol-induced dyskinesias controlled with dexmedetomidine during deep brain stimulation surgery.
Topics: Deep Brain Stimulation; Dexmedetomidine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Parkinson Disease; Propofol | 2006 |
Short duration large dose dexmedetomidine in a pediatric patient during procedural sedation.
Topics: Adrenergic alpha-Agonists; Child, Preschool; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Magnetic Resonance Angiography; Male; Propofol | 2006 |
Comparison of antimicrobial effects of dexmedetomidine and etomidate-lipuro with those of propofol and midazolam.
Topics: Acinetobacter baumannii; Adrenergic alpha-Agonists; Anesthetics, Intravenous; Anti-Infective Agents; Dexmedetomidine; Drug Evaluation, Preclinical; Equipment Contamination; Escherichia coli; Etomidate; Humans; Midazolam; Propofol; Pseudomonas aeruginosa; Staphylococcus aureus; Temperature; Time Factors | 2006 |
Propofol acts at the sigma-1 receptor and inhibits pentazocine-induced c-Fos expression in the mouse posterior cingulate and retrosplenial cortices.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Animals; Bradykinin; Calcium; Cells, Cultured; Dexmedetomidine; Droperidol; Gyrus Cinguli; Limbic System; Male; Mice; Mice, Inbred ICR; Pentazocine; Propofol; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Thiopental | 2006 |
[Effects of dexmedetomidine hydrochloride on postoperative sedation in cardiovascular surgery].
Topics: Aged; Anxiety; Cardiovascular Surgical Procedures; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Postoperative Care; Postoperative Complications; Propofol; Psychomotor Agitation | 2006 |
Dexmedetomidine sedation during awake craniotomy for seizure resection: effects on electrocorticography.
Topics: Adolescent; Adult; Anesthesia, General; Conscious Sedation; Craniotomy; Dexmedetomidine; Electroencephalography; Electrophysiology; Epilepsy; Female; Humans; Hypnotics and Sedatives; Laryngeal Masks; Male; Middle Aged; Propofol; Wakefulness | 2007 |
Initial experience with dexmedetomidine for diagnostic and interventional cardiac catheterization in children.
Topics: Analgesics, Non-Narcotic; Anesthetics, Intravenous; Blood Pressure; Cardiac Catheterization; Child; Child, Preschool; Dexmedetomidine; Electroencephalography; Heart Rate; Humans; Infant; Monitoring, Intraoperative; Propofol; Retrospective Studies; Time Factors; Treatment Outcome | 2007 |
Adjunctive dexmedetomidine therapy in the intensive care unit: a retrospective assessment of impact on sedative and analgesic requirements, levels of sedation and analgesia, and ventilatory and hemodynamic parameters.
Topics: Anesthetics; Databases as Topic; Dexmedetomidine; Female; Fentanyl; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Lorazepam; Male; Middle Aged; Propofol; Respiration; Retrospective Studies | 2007 |
Current state of sedation/analgesia care in dentistry.
Topics: Anesthesia, Dental; Conscious Sedation; Dental Anxiety; Dentistry; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Pain; Patient Satisfaction; Propofol | 2007 |
Current world literature.
Topics: Anesthesiology; Dexmedetomidine; Emergency Service, Hospital; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedatives; Nerve Block; Pain; Pain Management; Propofol | 2007 |
Dexmedetomidine for pediatric MRI sedation: a review of a series of cases.
Topics: Child; Child, Preschool; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infant; Magnetic Resonance Imaging; Male; Movement; Propofol; Retrospective Studies | 2007 |
[Experience in postoperative sedation with dexmedetomidine for mandibular osteotomy].
Topics: Adolescent; Adult; Child; Conscious Sedation; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Male; Mandible; Midazolam; Osteotomy; Postoperative Care; Propofol | 2007 |
Deep sedation with dexmedetomidine in a porcine model does not compromise the viability of free microvascular flap as depicted by microdialysis and tissue oxygen tension.
Topics: Animals; Blood Pressure; Cardiac Output; Cell Survival; Central Venous Pressure; Consciousness; Dexmedetomidine; Female; Glucose; Hypnotics and Sedatives; Lactic Acid; Microcirculation; Microdialysis; Models, Animal; Oxygen; Partial Pressure; Propofol; Pyruvic Acid; Rectus Abdominis; Surgical Flaps; Sus scrofa; Sympathectomy; Time Factors; Vascular Resistance | 2007 |
The use of dexmedetomidine during laryngoscopy, bronchoscopy, and tracheal extubation following tracheal reconstruction.
Topics: Adrenergic alpha-Agonists; Bronchoscopy; Child, Preschool; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Laryngoscopy; Male; Propofol; Trachea | 2007 |
Perioperative events during deep brain stimulation: the experience at cleveland clinic.
Topics: Age Factors; Aged; Analysis of Variance; Anesthesia, Intravenous; Anesthetics, Intravenous; Deep Brain Stimulation; Dexmedetomidine; Electrodes, Implanted; Female; Humans; Hypnotics and Sedatives; Intraoperative Complications; Male; Middle Aged; Neurosurgical Procedures; Postoperative Complications; Propofol; Prosthesis Implantation; Retrospective Studies; Risk Factors | 2008 |
Pro: dexmedetomidine should be used for infants and children undergoing cardiac surgery.
Topics: Analgesics; Anesthetics, Combined; Anesthetics, Intravenous; Cardiac Surgical Procedures; Catheterization; Child; Child, Preschool; Dexmedetomidine; Drug Administration Schedule; Heart Defects, Congenital; Humans; Infant; Ketamine; Postoperative Period; Propofol | 2008 |
[Ultra fast-track anesthesia with operating room extubation in a patient undergoing OPCABG by combination of propofol-remifentanil-dexmedetomidine].
Topics: Anesthesia Recovery Period; Anesthesia, General; Coronary Artery Bypass, Off-Pump; Coronary Stenosis; Dexmedetomidine; Humans; Intubation, Intratracheal; Male; Middle Aged; Operating Rooms; Perioperative Care; Piperidines; Propofol; Remifentanil; Ventilator Weaning | 2008 |
Successful intraoperative spinal cord monitoring during scoliosis surgery using a total intravenous anesthetic regimen including dexmedetomidine.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Anesthesia, Intravenous; Child; Dexmedetomidine; Drug Therapy, Combination; Evoked Potentials; Female; Fentanyl; Humans; Hypnotics and Sedatives; Male; Monitoring, Intraoperative; Orthopedic Procedures; Propofol; Scoliosis; Spinal Cord | 2008 |
Severe hypertension and bradycardia after dexmedetomidine for radiology sedation in a patient with acute transverse myelitis.
Topics: Adjuvants, Anesthesia; Adolescent; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Blood Pressure; Bradycardia; Brain; Dexmedetomidine; Flushing; Glycopyrrolate; Headache; Heart Rate; Humans; Hypertension; Magnetic Resonance Imaging; Male; Myelitis, Transverse; Propofol; Severity of Illness Index | 2008 |
Cost of dexmedetomidine in MRI.
Topics: Dexmedetomidine; Drug Costs; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Propofol | 2008 |
The effect of prolonged anesthesia with isoflurane, propofol, dexmedetomidine, or ketamine on neural cell proliferation in the adult rat.
Topics: Age Factors; Anesthetics; Animals; Bromodeoxyuridine; Cell Proliferation; Circadian Rhythm; Dentate Gyrus; Dexmedetomidine; Dose-Response Relationship, Drug; Hippocampus; Immunoenzyme Techniques; Isoflurane; Ketamine; Male; Neurons; Propofol; Rats; Rats, Sprague-Dawley | 2008 |
Propofol-sparing or lipid-sparing?
Topics: Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant; Infusions, Intravenous; Lipids; Propofol | 2009 |
Effects of dexmedetomidine on propofol and remifentanil infusion rates during total intravenous anesthesia for spine surgery in adolescents.
Topics: Adolescent; Adrenergic alpha-Agonists; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Child; Dexmedetomidine; Electroencephalography; Female; Heart Rate; Humans; Intraoperative Period; Male; Monitoring, Intraoperative; Piperidines; Propofol; Remifentanil; Retrospective Studies; Scoliosis; Spinal Fusion; Spine; Young Adult | 2008 |
Determination of the pharmacodynamic interaction of propofol and dexmedetomidine during esophagogastroduodenoscopy in children.
Topics: Child; Child, Preschool; Dexmedetomidine; Drug Therapy, Combination; Endoscopy, Digestive System; Female; Humans; Male; Predictive Value of Tests; Propofol; Regression Analysis | 2009 |
Expressions of genes encoding drug-metabolizing enzymes are altered after sevoflurane, isoflurane, propofol or dexmedetomidine anesthesia.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Dexmedetomidine; Gene Expression Regulation; Isoflurane; Liver; Male; Methyl Ethers; Oligonucleotide Array Sequence Analysis; Propofol; Rats; Rats, Wistar; Sevoflurane; Time Factors | 2009 |
Altered spontaneous contractions of the ileum by anesthetic agents in rats exposed to peritonitis.
Topics: Anesthetics, Intravenous; Animals; Dexmedetomidine; Gastrointestinal Motility; Ileum; Male; Midazolam; Muscle Contraction; Muscle, Smooth; Peritonitis; Propofol; Rats; Rats, Wistar | 2009 |
The influences of propofol and dexmedetomidine on circadian gene expression in rat brain.
Topics: Analysis of Variance; Animals; Basic-Leucine Zipper Transcription Factors; Brain; Catheterization; Cell Cycle Proteins; Circadian Rhythm; Cytoskeletal Proteins; Dexmedetomidine; DNA-Binding Proteins; Early Growth Response Protein 1; Early Growth Response Protein 2; Gene Expression; Hypnotics and Sedatives; Male; Nerve Tissue Proteins; Nuclear Proteins; Nuclear Receptor Subfamily 4, Group A, Member 1; Period Circadian Proteins; Propofol; Rats; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors | 2009 |
Influence of anesthetic management on quality of magnetoencephalography scan data in pediatric patients: a case series.
Topics: Adolescent; Analgesics, Non-Narcotic; Anesthesia; Anesthetics, Intravenous; Artifacts; Child; Child, Preschool; Dexmedetomidine; Dose-Response Relationship, Drug; Epilepsy; Female; Fentanyl; Humans; Magnetoencephalography; Male; Preoperative Care; Propofol; Retrospective Studies | 2009 |
A comparison of the effects on respiratory carbon dioxide response, arterial blood pressure, and heart rate of dexmedetomidine, propofol, and midazolam in sevoflurane-anesthetized rabbits.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Carbon Dioxide; Dexmedetomidine; Heart Rate; Methyl Ethers; Midazolam; Propofol; Rabbits; Respiration; Sevoflurane | 2009 |
Dexmedetomidine and proprofol in complex microlaryngeal surgery in infants.
Topics: Anesthesia; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant, Newborn; Laryngoscopy; Larynx; Laser Therapy; Microsurgery; Plastic Surgery Procedures; Propofol | 2009 |
A comparison of dexmedetomidine with propofol for magnetic resonance imaging sleep studies in children.
Topics: Adolescent; Anesthesia; Anesthetics, Intravenous; Child; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Male; Polysomnography; Propofol; Respiration; Retrospective Studies; Sleep Stages | 2009 |
Sedation and drugs in pediatric patients: what is new?
Topics: Anesthetics, Inhalation; Child; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Methyl Ethers; Propofol; Sevoflurane | 2009 |
[Effect of dexmedetomidine on intraoperative somatosensory evoked potential monitoring].
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Aged; Anesthesia; Dexmedetomidine; Evoked Potentials, Somatosensory; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Monitoring, Intraoperative; Neurosurgical Procedures; Propofol | 2009 |
Sedating the child with congenital heart disease.
Topics: Adolescent; Analgesia; Barbiturates; Benzodiazepines; Child; Child, Preschool; Conscious Sedation; Dexmedetomidine; Etomidate; Fentanyl; Heart Diseases; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Monitoring, Intraoperative; Practice Guidelines as Topic; Propofol | 2009 |
Effects of propofol and dexmedetomidine on indocyanine green elimination assessed with LIMON to patients with early septic shock: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Coloring Agents; Critical Illness; Dexmedetomidine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Indocyanine Green; Liver Circulation; Liver Function Tests; Male; Middle Aged; Pilot Projects; Propofol; Respiration, Artificial; Shock, Septic | 2009 |
Impact of dexmedetomidine on analgesic requirements in patients after cardiac surgery in a fast-track recovery room setting.
Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Cohort Studies; Coronary Artery Bypass; Dexmedetomidine; Drug Costs; Female; Hospitals, Teaching; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pain, Postoperative; Propofol; Respiration, Artificial; Retrospective Studies | 2009 |
Profound reduction in sedation and analgesic requirements using extended dexmedetomidine infusions in a patient with an open abdomen.
Topics: Abdominal Injuries; Analgesics, Non-Narcotic; Dexmedetomidine; Fentanyl; Humans; Infusions, Intravenous; Lorazepam; Male; Midazolam; Military Personnel; Pain Measurement; Propofol; Stress Disorders, Post-Traumatic; Wounds, Gunshot; Young Adult | 2009 |
[Effect of the initial loading dose of dexmedetomidine on hemodynamics in pediatric patients undergoing cardiac surgery].
Topics: Adrenergic Agonists; Anesthesia, Intravenous; Cardiac Surgical Procedures; Child; Child, Preschool; Dexmedetomidine; Female; Fentanyl; Heart Septal Defects, Ventricular; Hemodynamics; Humans; Infant; Male; Propofol | 2010 |
Evaluation of the hypnotic and hemodynamic effects of dexmedetomidine on propofol-sedated swine.
Topics: Anesthetics, Intravenous; Animals; Conscious Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Hemodynamics; Hypnotics and Sedatives; Male; Propofol; Swine; Vascular Resistance | 2010 |
Analysis of heart rate variability dynamics during propofol and dexmedetomidine anesthesia.
Topics: Analgesics, Non-Narcotic; Anesthetics, Intravenous; Computer Simulation; Dexmedetomidine; Drug Therapy, Combination; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Models, Cardiovascular; Models, Statistical; Propofol | 2010 |
Evaluation of dexmedetomidine versus propofol-based sedation therapy in mechanically ventilated cardiac surgery patients at a tertiary academic medical center.
Topics: Aged; Aged, 80 and over; Cardiac Surgical Procedures; Clinical Protocols; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Hypotension; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Pain; Pain Management; Palliative Care; Postoperative Care; Propofol; Research Design; Respiration, Artificial; Treatment Outcome | 2010 |
Post-operative dexmedetomidine-based sedation after uneventful intracranial surgery for unruptured cerebral aneurysm: comparison with propofol-based sedation.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Intracranial Aneurysm; Intubation, Intratracheal; Male; Middle Aged; Pain, Postoperative; Propofol; Retrospective Studies | 2011 |
Prevention of shivering during therapeutic temperature modulation: the Columbia anti-shivering protocol.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Anticonvulsants; Conscious Sedation; Critical Care; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Fever; Glasgow Coma Scale; Heart Arrest; Humans; Hypothermia, Induced; Intensive Care Units; Intracranial Hypertension; Magnesium Sulfate; Male; Meperidine; Middle Aged; Monitoring, Physiologic; Narcotics; Neuromuscular Nondepolarizing Agents; Propofol; Prospective Studies; Shivering; Vecuronium Bromide | 2011 |
Takotsubo cardiomyopathy and the difficult airway.
Topics: Airway Obstruction; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Laryngoscopy; Piperidines; Propofol; Remifentanil; Takotsubo Cardiomyopathy | 2011 |
Volatile agents for ICU sedation?
Topics: Anesthesia, Inhalation; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Midazolam; Propofol; Volatile Organic Compounds | 2011 |
Evaluation of dexmedetomidine: safety and clinical outcomes in critically ill trauma patients.
Topics: Adult; Analgesics; Antipsychotic Agents; Chi-Square Distribution; Critical Illness; Dexmedetomidine; Endpoint Determination; Female; Heart Rate; Humans; Hypnotics and Sedatives; Hypotension; Infusions, Intravenous; Length of Stay; Male; Middle Aged; Propofol; Registries; Respiration, Artificial; Retrospective Studies; Statistics, Nonparametric; Time Factors; Wounds and Injuries | 2011 |
Wide inter-individual variability of bispectral index and spectral entropy at loss of consciousness during increasing concentrations of dexmedetomidine, propofol, and sevoflurane.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Consciousness Monitors; Data Interpretation, Statistical; Dexmedetomidine; Dose-Response Relationship, Drug; Entropy; Humans; Hypnotics and Sedatives; Male; Methyl Ethers; Propofol; Reproducibility of Results; Sevoflurane; Unconsciousness; Young Adult | 2011 |
Effect of a dexmedetomidine substitution during a nationwide propofol shortage in patients undergoing coronary artery bypass graft surgery.
Topics: Academic Medical Centers; Aged; Analgesics, Opioid; Case-Control Studies; Coronary Artery Bypass; Critical Care; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol; Retrospective Studies; Time Factors | 2011 |
Consciousness lost and found: subjective experiences in an unresponsive state.
Topics: Adolescent; Adult; Anesthetics; Brain; Consciousness; Dexmedetomidine; Electroencephalography; Humans; Hypnotics and Sedatives; Male; Methyl Ethers; Propofol; Sevoflurane; Xenon | 2011 |
Consciousness versus responsiveness: insights from general anesthetics.
Topics: Anesthetics; Consciousness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Male; Methyl Ethers; Propofol; Sevoflurane; Xenon | 2011 |
Dexmedetomidine and hydroxyzine synergistically potentiate the hypnotic activity of propofol in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Drug Synergism; Histamine H1 Antagonists; Hydroxyzine; Hypnotics and Sedatives; Male; Mice; Motor Activity; Propofol; Receptors, GABA-A | 2012 |
Weighing the costs and benefits of a sedative.
Topics: Communication; Conscious Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Propofol; Respiration, Artificial | 2012 |
Opioid-free perioperative analgesia for hemicolectomy in a patient with opioid-induced delirium: a case report and review of the analgesic efficacy of the alpha-2 agonist agents.
Topics: Abdominal Abscess; Adrenergic alpha-2 Receptor Agonists; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Intravenous; Bupivacaine; Clonidine; Colectomy; Delirium; Dexmedetomidine; Female; Humans; Infusions, Intravenous; Pain, Postoperative; Postoperative Complications; Propofol; Young Adult | 2012 |
Dexmedetomidine dose dependently decreases oral tissue blood flow during sevoflurane and propofol anesthesia in rabbits.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Pressure; Bone Marrow; Carotid Artery, Common; Dexmedetomidine; Dose-Response Relationship, Drug; Heart Rate; Hypnotics and Sedatives; Laser-Doppler Flowmetry; Male; Mandible; Masseter Muscle; Methyl Ethers; Mouth; Mouth Mucosa; Propofol; Pulmonary Alveoli; Rabbits; Regional Blood Flow; Respiration, Artificial; Sevoflurane; Tongue; Tracheotomy; Vascular Resistance | 2012 |
Medications for sedation in patients with prolonged mechanical ventilation.
Topics: Communication; Conscious Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Propofol; Respiration, Artificial | 2012 |
Effects of propofol and dexmedetomidine on motor coordination and analgesia: a comparative analysis.
Topics: Analgesics; Animals; Behavior, Animal; Dexmedetomidine; Disease Models, Animal; Hot Temperature; Male; Motor Skills; Pain; Pain Measurement; Pain Threshold; Propofol; Rats; Reaction Time; Time Factors | 2012 |
Anesthetic effects on susceptibility to cortical spreading depression.
Topics: Anesthetics; Animals; Cortical Spreading Depression; Dexmedetomidine; Isoflurane; Male; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley | 2013 |
Apheresis in three dogs weighing <14 kg.
Topics: Anesthetics; Animals; Blood Component Removal; Body Weight; Dexmedetomidine; Dogs; Hypnotics and Sedatives; Lymphoma; Male; Propofol | 2013 |
Effects of dexmedetomidine, midazolam, and propofol on acetylcholine release in the rat cerebral cortex in vivo.
Topics: Acetylcholine; Animals; Cerebral Cortex; Dexmedetomidine; Male; Midazolam; Propofol; Rats; Rats, Wistar | 2013 |
Treatment of post-electroconvulsive therapy agitation with dexmedetomidine.
Topics: Aged; Depressive Disorder, Major; Dexmedetomidine; Electroconvulsive Therapy; Humans; Hypnotics and Sedatives; Male; Midazolam; Propofol; Psychomotor Agitation | 2013 |
Impact of a protocol advocating dexmedetomidine over propofol sedation after robotic-assisted direct coronary artery bypass surgery on duration of mechanical ventilation and patient safety.
Topics: Aged; Analgesics, Opioid; Coronary Artery Bypass; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Morphine; Patient Safety; Postoperative Care; Propofol; Respiration, Artificial; Retrospective Studies; Robotics | 2013 |
Pharmacology of intravenous sedative/anesthetic medications used in oral surgery.
Topics: Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Dental; Anesthetics, Dissociative; Anesthetics, Intravenous; Benzodiazepines; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Ketamine; Oral Surgical Procedures; Propofol; Thiopental | 2013 |
Dexmedetomidine use in the ICU: are we there yet?
Topics: Communication; Conscious Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Propofol; Respiration, Artificial | 2013 |
The hemodynamic effects of dexmedetomidine and esmolol in electroconvulsive therapy: a retrospective comparison.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Adult; Anesthetics, Intravenous; Autonomic Nervous System; Dexmedetomidine; Electroconvulsive Therapy; Female; Hemodynamics; Humans; Hypertension; Hypnotics and Sedatives; Male; Middle Aged; Propanolamines; Propofol; Retrospective Studies; Tachycardia; Treatment Outcome; Young Adult | 2013 |
Propofol-based versus dexmedetomidine-based sedation in cardiac surgery patients.
Topics: Aged; Airway Extubation; Airway Management; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Conscious Sedation; Costs and Cost Analysis; Critical Care; Databases, Factual; Dexmedetomidine; Female; Hospital Mortality; Humans; Hypnotics and Sedatives; Longevity; Male; Propofol; Respiration, Artificial; Retrospective Studies; Socioeconomic Factors | 2013 |
The effect of four anaesthetic protocols for maintenance of anaesthesia on trans-diaphragmatic pressure in dogs.
Topics: Anesthesia; Anesthetics; Animals; Dexmedetomidine; Dogs; Female; Fentanyl; Isoflurane; Ketamine; Male; Morphine; Propofol | 2013 |
Clinical and economic impact of substituting dexmedetomidine for propofol due to a US drug shortage: examination of coronary artery bypass graft patients at an urban medical centre.
Topics: Cohort Studies; Coronary Artery Bypass; Cost-Benefit Analysis; Dexmedetomidine; Drug Utilization; Hospitals, Urban; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Male; Middle Aged; Multivariate Analysis; Postoperative Complications; Propofol; Respiration, Artificial; Retrospective Studies; United States | 2014 |
Dexmedetomidine and propofol total intravenous anesthesia for airway foreign body removal.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Aged, 80 and over; Anesthesia; Anesthesia, Intravenous; Bronchi; Bronchoscopy; Child, Preschool; Dexmedetomidine; Female; Foreign Bodies; Hemodynamics; Humans; Hypnotics and Sedatives; Infant; Male; Propofol; Trachea | 2014 |
A comparison of severe hemodynamic disturbances between dexmedetomidine and propofol for sedation in neurocritical care patients.
Topics: Academic Medical Centers; Adolescent; Adult; Aged; Aged, 80 and over; Bradycardia; Critical Care; Dexmedetomidine; Female; Health Status Indicators; Hemodynamics; Humans; Hypnotics and Sedatives; Hypotension; Infusions, Intravenous; Male; Middle Aged; Nervous System Diseases; Prevalence; Propofol; Retrospective Studies | 2014 |
Sedation, analgesia, and anaesthesia variability in laboratory-based cardiac procedures: an international survey.
Topics: Anesthesia, General; Anesthesiology; Anesthetics, Intravenous; Attitude of Health Personnel; Benzodiazepines; Cardiovascular Surgical Procedures; Clinical Competence; Conscious Sedation; Deep Sedation; Dexmedetomidine; Diagnostic Techniques, Cardiovascular; Drug Utilization; Fentanyl; Humans; Hypnotics and Sedatives; Internationality; Morphine; Piperidines; Practice Patterns, Nurses'; Practice Patterns, Physicians'; Propofol; Remifentanil; Surveys and Questionnaires | 2014 |
Cost effectiveness of a benzodiazepine vs a nonbenzodiazepine-based sedation regimen for mechanically ventilated, critically ill adults.
Topics: Adult; Benzodiazepines; Clinical Protocols; Cost-Benefit Analysis; Critical Illness; Dexmedetomidine; Drug Costs; Humans; Hypnotics and Sedatives; Intensive Care Units; Markov Chains; Propofol; Respiration, Artificial; Sensitivity and Specificity | 2014 |
Comparison of Dexmedetomidine Versus Propofol on Hospital Costs and Length of Stay.
Topics: Adult; Aged; Conscious Sedation; Critical Care; Critical Illness; Dexmedetomidine; Female; Hospital Costs; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Male; Middle Aged; Propofol; Quality Improvement; Retrospective Studies; United States | 2016 |
Correlation of patient-reported outcomes of sedation and sedation assessment scores in critically ill patients.
Topics: Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Patient Outcome Assessment; Patient-Centered Care; Propofol; Prospective Studies; Psychomotor Agitation; Respiration, Artificial | 2014 |
Evaluating effective dose of dexmedetomidine: onset time of drug is critical.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Laryngeal Masks; Male; Preanesthetic Medication; Propofol | 2014 |
Effects of short-term propofol and dexmedetomidine on pulmonary morphofunction and biological markers in experimental mild acute lung injury.
Topics: Acute Lung Injury; Animals; Cytokines; Dexmedetomidine; Disease Models, Animal; Endotoxins; Female; Hypnotics and Sedatives; Lipopolysaccharides; Lung; NF-E2 Transcription Factor; Nitric Oxide Synthase; Propofol; Rats; Rats, Wistar; RNA, Messenger; Statistics, Nonparametric; Thiopental | 2014 |
Dexmedetomidine in the treatment of serotonin syndrome.
Topics: Adolescent; Adrenergic alpha-Agonists; Benzodiazepines; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Propofol; Psychomotor Agitation; Serotonin Syndrome; Treatment Failure | 2014 |
A comparison of propofol- and dexmedetomidine-induced electroencephalogram dynamics using spectral and coherence analysis.
Topics: Adolescent; Adult; Anesthetics, Intravenous; Behavior; Data Interpretation, Statistical; Dexmedetomidine; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Male; Propofol; Unconsciousness; Young Adult | 2014 |
Response Letter to Dr Li et al.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Laryngeal Masks; Male; Preanesthetic Medication; Propofol | 2014 |
Electroencephalogram reactivity to verbal command after dexmedetomidine, propofol and sevoflurane-induced unresponsiveness.
Topics: Adult; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Deep Sedation; Dexmedetomidine; Electroencephalography; Fourier Analysis; Humans; Hypnotics and Sedatives; Male; Methyl Ethers; Propofol; Sevoflurane; Verbal Behavior; Young Adult | 2015 |
Effects of propofol-dexmedetomidine combination on ischemia reperfusion-induced cerebral injury.
Topics: Animals; Dexmedetomidine; Drug Therapy, Combination; Infarction, Middle Cerebral Artery; Male; Propofol; Rats; Rats, Sprague-Dawley | 2014 |
Optimal doses of sevoflurane and propofol in rabbits.
Topics: Anesthesia; Animals; Blood Pressure; Body Temperature; Consciousness Monitors; Dexmedetomidine; Dose-Response Relationship, Drug; Heart Rate; Linear Models; Methyl Ethers; Propofol; Rabbits; Sevoflurane; Systole | 2014 |
Multicenter evaluation of pharmacologic management and outcomes associated with severe resistant alcohol withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Antipsychotic Agents; Benzodiazepines; Cross Infection; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Male; Middle Aged; Pneumonia; Propofol; Respiration, Artificial; Retrospective Studies | 2015 |
Raising the bar for pediatric sedation studies and trials.
Topics: Anesthetics, Intravenous; Dexmedetomidine; Female; Humans; Piperidines; Propofol | 2015 |
Effect of dexemeditomedine and propofol on the prevention of emergence agitation following sevoflurane anesthesia in Egyptian children.
Topics: Adjuvants, Anesthesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Child, Preschool; Dexmedetomidine; Egypt; Female; Fentanyl; Humans; Hypnotics and Sedatives; Male; Methyl Ethers; Postoperative Complications; Propofol; Sevoflurane | 2014 |
Dexmedetomidine Sedation for WADA Test With Intracarotid Propofol in Pediatric Patients.
Topics: Amobarbital; Anesthetics, Intravenous; Carotid Arteries; Catheterization; Child; Conscious Sedation; Dexmedetomidine; Electroencephalography; Female; Femoral Artery; Functional Laterality; Humans; Hypnotics and Sedatives; Language; Male; Memory; Propofol; Wakefulness | 2015 |
Emergence delirium in children.
Topics: Anesthesia, General; Delirium; Dexmedetomidine; Female; Humans; Magnetic Resonance Imaging; Male; Propofol | 2015 |
Drug fever caused by propofol in the intensive care unit.
Topics: Dexmedetomidine; Female; Fever; Humans; Hypnotics and Sedatives; Intensive Care Units; Middle Aged; Propofol | 2015 |
Is dexmedetomidine really superior to propofol?
Topics: Cerebral Angiography; Dexmedetomidine; Female; Humans; Male; Propofol; Subarachnoid Hemorrhage | 2015 |
Dexmedetomidine Attenuates Neurotoxicity Induced by Prenatal Propofol Exposure.
Topics: Anesthetics, Intravenous; Animals; Blotting, Western; Brain; Calcium-Binding Proteins; Caspase 3; Dexmedetomidine; Disease Models, Animal; Female; Hypnotics and Sedatives; Microfilament Proteins; Neurotoxicity Syndromes; Pregnancy; Prenatal Exposure Delayed Effects; Propofol; Rats; Rats, Sprague-Dawley | 2016 |
[Ventricular fibrillation and cardiorespiratory arrest during dexmedetomidine administration].
Topics: Adrenergic alpha-2 Receptor Agonists; Advanced Cardiac Life Support; Aged; Airway Extubation; Aortic Valve Stenosis; Dexmedetomidine; Drug Substitution; Electric Countershock; Heart Arrest; Heart Valve Prosthesis Implantation; Humans; Hypnotics and Sedatives; Hypotension; Male; Postoperative Complications; Propofol; Psychomotor Agitation; Ventricular Fibrillation | 2015 |
In reply: is dexmedetomidine really superior to propofol?
Topics: Cerebral Angiography; Dexmedetomidine; Female; Humans; Male; Propofol; Subarachnoid Hemorrhage | 2015 |
Efficacy of concomitant use of dexmedetomidine and propofol in tetanus.
Topics: Aged; Dexmedetomidine; Drug Therapy, Combination; Humans; Hypnotics and Sedatives; Male; Propofol; Tetanus | 2015 |
Revision of loop colostomy under regional anaesthesia and sedation.
Topics: Abdominal Wall; Aged; Anesthesia, Conduction; Anesthesia, General; Colostomy; Conscious Sedation; Dexmedetomidine; Fentanyl; Hemodynamics; Humans; Ketamine; Laparoscopy; Male; Nerve Block; Pain, Postoperative; Postoperative Period; Propofol; Pulmonary Embolism; Reoperation; Tachycardia, Supraventricular; Ultrasonography, Interventional | 2015 |
Is critical care ready for an economic surrogate endpoint?
Topics: Conscious Sedation; Dexmedetomidine; Hospitalization; Humans; Hypnotics and Sedatives; Midazolam; Propofol | 2015 |
Different effects of propofol and dexmedetomidine on preload dependency in endotoxemic shock with norepinephrine infusion.
Topics: Animals; Blood Pressure; Cardiac Output; Dexmedetomidine; Endotoxemia; Heart Rate; Norepinephrine; Propofol; Rabbits; Shock, Septic; Systole | 2015 |
Safety and Hemodynamic Profile of Propofol and Dexmedetomidine Anesthesia during Intra-arterial Acute Stroke Therapy.
Topics: Aged; Aged, 80 and over; Blood Pressure; Brain Ischemia; Dexmedetomidine; Diffusion Magnetic Resonance Imaging; Female; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Infusions, Intra-Arterial; Male; Middle Aged; Propofol; Retrospective Studies; Stroke; Treatment Outcome | 2015 |
Propofol-induced electroencephalogram dynamics: a missing piece.
Topics: Anesthetics, Intravenous; Dexmedetomidine; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Male; Propofol | 2015 |
In reply.
Topics: Anesthetics, Intravenous; Dexmedetomidine; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Male; Propofol | 2015 |
Feasibility of deep sedation with a combination of propofol and dexmedetomidine hydrochloride for esophageal endoscopic submucosal dissection.
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Deep Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endoscopic Mucosal Resection; Feasibility Studies; Female; Follow-Up Studies; Gastric Mucosa; Gastroscopy; Humans; Male; Middle Aged; Propofol; Retrospective Studies; Stomach Neoplasms; Time Factors; Treatment Outcome | 2016 |
Associations Between Different Sedatives and Ventilator-Associated Events, Length of Stay, and Mortality in Patients Who Were Mechanically Ventilated.
Topics: Adult; Aged; Airway Extubation; Benzodiazepines; Comparative Effectiveness Research; Conscious Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Length of Stay; Male; Middle Aged; Outcome and Process Assessment, Health Care; Propofol; Respiration, Artificial; Retrospective Studies; Time Factors; United States; Ventilators, Mechanical | 2016 |
Changes in QTc associated with a rapid bolus dose of dexmedetomidine in patients receiving TIVA: a retrospective study.
Topics: Administration, Intravenous; Anesthesia, Intravenous; Anesthetics, Intravenous; Child; Child, Preschool; Dexmedetomidine; Electrocardiography; Female; Heart Rate; Humans; Long QT Syndrome; Male; Monitoring, Intraoperative; Piperidines; Propofol; Remifentanil; Retrospective Studies | 2015 |
Dexmedetomidine and emergence agitation.
Topics: Anesthesia, General; Delirium; Dexmedetomidine; Female; Humans; Magnetic Resonance Imaging; Male; Propofol | 2015 |
A reply.
Topics: Anesthesia, General; Delirium; Dexmedetomidine; Female; Humans; Magnetic Resonance Imaging; Male; Propofol | 2015 |
A comparison of dexmedetomidine versus propofol during drug-induced sleep endoscopy in sleep apnea patients.
Topics: Adult; Airway Management; Anesthetics, Intravenous; Cohort Studies; Dexmedetomidine; Endoscopy; Female; Humans; Male; Middle Aged; Propofol; Prospective Studies; Risk Assessment; Sleep; Sleep Apnea, Obstructive; Statistics, Nonparametric; Treatment Outcome; Young Adult | 2016 |
General anesthetics have differential inhibitory effects on gap junction channels and hemichannels in astrocytes and neurons.
Topics: Anesthetics, General; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Connexins; Dexmedetomidine; Fluorescent Antibody Technique; Gap Junctions; Green Fluorescent Proteins; Ketamine; Lipopolysaccharides; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Propofol; Tissue Culture Techniques; Voltage-Sensitive Dye Imaging | 2016 |
Inhibition of the cardiac Na⁺ channel α-subunit Nav1.5 by propofol and dexmedetomidine.
Topics: Dexmedetomidine; HEK293 Cells; Humans; Hypnotics and Sedatives; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Propofol; Sodium Channel Blockers | 2016 |
The Effects of Short-Term Propofol and Dexmedetomidine on Lung Mechanics, Histology, and Biological Markers in Experimental Obesity.
Topics: Animals; Biomarkers; Dexmedetomidine; Lung; Male; Obesity; Propofol; Rats; Rats, Wistar; Respiration, Artificial; Respiratory Mechanics; Treatment Outcome | 2016 |
Outcomes of Patients with Alcohol Withdrawal Syndrome Treated with High-Dose Sedatives and Deferred Intubation.
Topics: Adult; Alcohol Withdrawal Seizures; APACHE; Central Nervous System Depressants; Cohort Studies; Critical Illness; Dexmedetomidine; Ethanol; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Intubation, Intratracheal; Length of Stay; Logistic Models; Lorazepam; Male; Midazolam; Middle Aged; Pneumonia; Propofol; Respiration, Artificial; Retrospective Studies; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome | 2016 |
Variable Findings for Drug-Induced Sleep Endoscopy in Obstructive Sleep Apnea with Propofol versus Dexmedetomidine.
Topics: Adult; Dexmedetomidine; Endoscopy; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol; Sleep; Sleep Apnea, Obstructive | 2016 |
[Anesthetic Management for Lobectomy in a Patient with Pulmonary Arterial Hypertension].
Topics: Aged; Anesthesia; Dexmedetomidine; Female; Fentanyl; Humans; Hypertension, Pulmonary; Lung Neoplasms; Phenylpropionates; Pneumonectomy; Propofol; Pyridazines | 2016 |
Comparison of sedation method in pediatrics cardiac catheterization.
Topics: Anesthesia Recovery Period; Cardiac Catheterization; Child; Dexmedetomidine; Heart Rate; Humans; Hypnotics and Sedatives; Propofol; Prospective Studies | 2016 |
Comparison of the combination of dexmedetomidine and ketamine to propofol or propofol/sevoflurane for drug-induced sleep endoscopy in children.
Topics: Airway Obstruction; Analgesics; Anesthetics, Inhalation; Anesthetics, Intravenous; Causality; Child; Dexmedetomidine; Drug Therapy, Combination; Endoscopy; Female; Humans; Hypnotics and Sedatives; Ketamine; Male; Methyl Ethers; Propofol; Retrospective Studies; Sevoflurane; Sleep; Sleep Apnea, Obstructive | 2016 |
Dexmedetomidine attenuates repeated propofol exposure-induced hippocampal apoptosis, PI3K/Akt/Gsk-3β signaling disruption, and juvenile cognitive deficits in neonatal rats.
Topics: Analgesics; Animals; Apoptosis; bcl-2-Associated X Protein; Biomarkers; Blood Gas Analysis; Caspase 3; Cognitive Dysfunction; Dexmedetomidine; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Hippocampus; Male; Phosphatidylinositol 3-Kinases; Propofol; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction | 2016 |
Growth in an Anesthesiologist- and Nurse Anesthetist-Supervised Sedation Nurse Program Using Propofol and Dexmedetomidine.
Topics: Adolescent; Adult; Anesthesiologists; Child; Child, Preschool; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Male; Middle Aged; Nurse Anesthetists; Program Development; Propofol; Prospective Studies; Young Adult | 2016 |
The relationship between sedative drug utilization and outcomes in critically ill patients undergoing mechanical ventilation.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Benzodiazepines; Critical Illness; Dexmedetomidine; Drug Utilization; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Japan; Length of Stay; Male; Middle Aged; Propofol; Respiration, Artificial | 2016 |
Dexmedetomidine pretreatment attenuates propofol‑induced neurotoxicity in neuronal cultures from the rat hippocampus.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Intravenous; Animals; Animals, Newborn; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dexmedetomidine; Female; Hippocampus; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Propofol; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2016 |
Evaluation of sedatives, analgesics, and neuromuscular blocking agents in adults receiving extracorporeal membrane oxygenation.
Topics: Adult; Analgesics; Analgesics, Opioid; Benzodiazepines; Dexmedetomidine; Extracorporeal Membrane Oxygenation; Female; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Neuromuscular Blocking Agents; Propofol; Prospective Studies | 2017 |
Gum elastic bougie-guided insertion of laryngeal tube suction-II in patients with difficult airway.
Topics: Adult; Airway Management; Anesthesia, Inhalation; Anesthetics, Intravenous; Burns; Contracture; Dexmedetomidine; Female; Humans; Humeral Fractures; Larynx; Middle Aged; Neck Muscles; Propofol | 2016 |
Assessing interaction between dexmedetomidine and propofol.
Topics: Dexmedetomidine; Hypnotics and Sedatives; Propofol; Respiration, Artificial | 2017 |
A retrospective comparison of propofol alone to propofol in combination with dexmedetomidine for pediatric 3T MRI sedation.
Topics: Airway Obstruction; Child, Preschool; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Male; Propofol; Retrospective Studies | 2017 |
Differential role of intravenous anesthetics in colorectal cancer progression: implications for clinical application.
Topics: Anesthetics, Intravenous; Animals; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Dexmedetomidine; Disease Progression; Epithelial-Mesenchymal Transition; Etomidate; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Mice; Neoplasm Metastasis; Phosphatidylinositol 3-Kinases; Prognosis; Propofol; Proto-Oncogene Proteins c-akt; Signal Transduction | 2016 |
In reply: Assessing interaction between dexmedetomidine and propofol.
Topics: Dexmedetomidine; Hypnotics and Sedatives; Propofol; Respiration, Artificial | 2017 |
Does dexmedetomidine cause less airway collapse than propofol when used for deep sedation?
Topics: Airway Obstruction; Anesthesia; Anesthetics, Inhalation; Child; Child, Preschool; Deep Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Imaging, Three-Dimensional; Infusions, Intravenous; Magnetic Resonance Imaging; Male; Methyl Ethers; Propofol; Sevoflurane | 2016 |
A comparison between dexmedetomidine and propofol on extubation times in postoperative adult cardiac surgery patients: a systematic review protocol.
Topics: Airway Extubation; Cardiac Surgical Procedures; Dexmedetomidine; Humans; Hypnotics and Sedatives; Length of Stay; Propofol; Systematic Reviews as Topic; Time Factors | 2016 |
Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose.
Topics: Adult; Carisoprodol; Dexmedetomidine; Drug Overdose; Fentanyl; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Units; Ketamine; Lorazepam; Male; Midazolam; Propofol; Quetiapine Fumarate; Respiration, Artificial; Substance Withdrawal Syndrome; Substance-Related Disorders | 2017 |
The efficacy of dexmedetomidine-remifentanil versus dexmedetomidine-propofol in children undergoing flexible bronchoscopy: A retrospective trial.
Topics: Anesthesia; Anesthesia Recovery Period; Blood Pressure; Bronchoscopy; Child; China; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Monitoring; Female; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Piperidines; Propofol; Remifentanil; Respiratory Tract Diseases; Retrospective Studies; Treatment Outcome | 2017 |
Prevention and Therapy of Pediatric Emergence Delirium: A National Survey.
Topics: Child; Dexmedetomidine; Emergence Delirium; Humans; Midazolam; Pediatrics; Propofol | 2017 |
General anesthesia with a native airway for patients with mucopolysaccharidosis type III.
Topics: Adolescent; Airway Management; Anesthesia, General; Anesthetics, Intravenous; Child; Child, Preschool; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Methyl Ethers; Mucopolysaccharidosis III; Patient Positioning; Propofol; Prospective Studies; Sevoflurane | 2017 |
MRI Sedation for Patient With Spinal Myoclonus.
Topics: Adult; Anesthetics, Intravenous; Brain; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Male; Myoclonus; Propofol; Spinal Cord | 2018 |
Acoustic analysis of snoring sounds originating from different sources determined by drug-induced sleep endoscopy.
Topics: Adult; Dexmedetomidine; Epiglottis; Female; Humans; Hypnotics and Sedatives; Laryngoscopy; Male; Middle Aged; Palate, Soft; Pharynx; Propofol; Snoring; Tongue; Video Recording; Young Adult | 2017 |
Comment on Growth in an Anesthesiologist and Nurse Anesthetist-Supervised Sedation Nurse Program Using Propofol and Dexmedetomidine.
Topics: Anesthesiologists; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Nurse Anesthetists; Propofol | 2017 |
In Response.
Topics: Anesthesia; Anesthesiologists; Dexmedetomidine; Humans; Nurse Anesthetists; Propofol | 2017 |
Effects of propofol and dexmedetomidine anesthesia on Th1/Th2 of rat spinal cord injury.
Topics: Anesthesia; Animals; Cytokines; Dexmedetomidine; Propofol; Rats; Spinal Cord Injuries; Th1-Th2 Balance; Time Factors | 2017 |
Dexmedetomidine attenuates propofol-induce neuroapoptosis partly via the activation of the PI3k/Akt/GSK3β pathway in the hippocampus of neonatal rats.
Topics: Anesthetics, Intravenous; Animals; Animals, Newborn; Apoptosis; Chromones; Dexmedetomidine; Female; Glycogen Synthase Kinase 3 beta; Hippocampus; Male; Morpholines; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Propofol; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Thiadiazoles | 2017 |
Quantitative analyses of the global proteome and phosphoproteome reveal the different impacts of propofol and dexmedetomidine on HT22 cells.
Topics: Animals; Cell Line; Chromatography, Affinity; Chromatography, Liquid; Dexmedetomidine; Isotope Labeling; Mice; Neurons; Phosphoproteins; Propofol; Protein Interaction Maps; Proteomics; Tandem Mass Spectrometry | 2017 |
Intraoperative dexmedetomidine sedation reduces the postoperative agitated behavior in elderly patients undergoing orthopedic surgery compared to the propofol sedation.
Topics: Aged; Deep Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Incidence; Intraoperative Care; Male; Orthopedic Procedures; Postoperative Complications; Propofol; Psychomotor Agitation; Retrospective Studies; Risk Factors | 2017 |
Awake craniotomy anesthetic management using dexmedetomidine, propofol, and remifentanil.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Brain Neoplasms; Craniotomy; Dexmedetomidine; Female; Glioma; Humans; Male; Middle Aged; Piperidines; Propofol; Remifentanil; Retrospective Studies; Wakefulness | 2017 |
Effects of ketamine, dexmedetomidine and propofol anesthesia on emotional memory consolidation in rats: Consequences for the development of post-traumatic stress disorder.
Topics: Animals; Avoidance Learning; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Hypnotics and Sedatives; Inhibition, Psychological; Interpersonal Relations; Ketamine; Male; Memory Disorders; Propofol; Rats; Rats, Sprague-Dawley; Sleep Wake Disorders; Stress Disorders, Post-Traumatic | 2017 |
Effect of Dexmedetomidine and Propofol on Basal Ganglia Activity in Parkinson Disease: A Controlled Clinical Trial.
Topics: Action Potentials; Aged; Basal Ganglia; Deep Brain Stimulation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Parkinson Disease; Propofol | 2017 |
Effect of dexmedetomidine and midazolam for flexible fiberoptic bronchoscopy in intensive care unit patients: A retrospective study.
Topics: Bronchoscopy; China; Critical Care; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Propofol; Respiration, Artificial; Retrospective Studies | 2017 |
Does dexmedetomidine offer brain protection?
Topics: Brain; Conscious Sedation; Craniotomy; Dexmedetomidine; Epilepsy; Humans; Propofol; Remifentanil; Wakefulness | 2017 |
Sedation After Cardiac Surgery With Propofol or Dexmedetomidine: Between Scylla and Charybdis?
Topics: Cardiac Surgical Procedures; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol | 2017 |
In Response: Sedation After Cardiac Surgery With Propofol or Dexmedetomidine: Between Scylla and Charybdis?
Topics: Cardiac Surgical Procedures; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol | 2017 |
Anaesthesia management in epilepsy surgery with intraoperative electrocorticography.
Topics: Amygdala; Anesthesia, General; Anesthetics; Anticonvulsants; Brain Waves; Combined Modality Therapy; Dexmedetomidine; Drug Resistant Epilepsy; Electrocorticography; Epilepsies, Partial; Female; Fentanyl; Hippocampus; Humans; Intraoperative Neurophysiological Monitoring; Middle Aged; Neurosurgical Procedures; Propofol; Remifentanil; Rocuronium | 2018 |
Partial neuromuscular block impairs arytenoid abduction during hypercarbic challenge in anesthetized dogs.
Topics: Anesthesia, General; Anesthesia, Intravenous; Animals; Carbon Dioxide; Dexmedetomidine; Dogs; Hypercapnia; Laryngeal Muscles; Laryngoscopy; Male; Neuromuscular Blockade; Propofol | 2017 |
Maternal and fetal effects of dexmedetomidine infusion in pregnant ewes anesthetized with sevoflurane.
Topics: Anesthesia; Animals; Blood Pressure; Dexmedetomidine; Female; Fetus; Heart Rate; Hemodynamics; Infusions, Intravenous; Methyl Ethers; Pregnancy; Propofol; Sevoflurane; Sheep; Thermodilution; Vascular Resistance | 2017 |
Brain functional connectivity differentiates dexmedetomidine from propofol and natural sleep.
Topics: Adolescent; Adult; Anesthetics, Intravenous; Brain; Brain Mapping; Consciousness; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Neural Pathways; Propofol; Sleep; Young Adult | 2017 |
Pharmacokinetics of dexmedetomidine administered to patients with end-stage renal failure and secondary hyperparathyroidism undergoing general anaesthesia.
Topics: Adult; Anesthesia, General; Case-Control Studies; Dexmedetomidine; Female; Half-Life; Humans; Hyperparathyroidism, Secondary; Hypnotics and Sedatives; Kidney Failure, Chronic; Male; Middle Aged; Models, Biological; Nonlinear Dynamics; Propofol | 2018 |
A Pilot Analysis of the Association Between Types of Monitored Anesthesia Care Drugs and Outcomes in Transfemoral Aortic Valve Replacement Performed Without General Anesthesia.
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Intravenous; Conscious Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pilot Projects; Propofol; Retrospective Studies; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2018 |
The influence of norepinephrine and phenylephrine on cerebral perfusion and oxygenation during propofol-remifentanil and propofol-remifentanil-dexmedetomidine anaesthesia in piglets.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Blood Circulation; Cerebral Cortex; Dexmedetomidine; Hypnotics and Sedatives; Norepinephrine; Oxygen; Phenylephrine; Piperidines; Propofol; Remifentanil; Swine; Vasoconstrictor Agents | 2018 |
Dexmedetomidine versus propofol-opioid for sedation in transcatheter aortic valve implantation patients: a retrospective analysis of periprocedural gas exchange and hemodynamic support.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, General; Aortic Valve Stenosis; Carbon Dioxide; Cohort Studies; Conscious Sedation; Dexmedetomidine; Endpoint Determination; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Propofol; Pulmonary Gas Exchange; Retrospective Studies; Risk Assessment; Transcatheter Aortic Valve Replacement | 2018 |
Effect of Sedation Regimen on Weaning from Mechanical Ventilation in the Intensive Care Unit.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Critical Care; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Pain; Propofol; Quality of Life; Respiration, Artificial; Retrospective Studies; Stress Disorders, Post-Traumatic; Sweden; Ventilator Weaning; Young Adult | 2018 |
Determination of dexmedetomidine by UHPLC-MS/MS and its application to evaluate the effect of dexmedetomidine concentration on the target-controlled infusion concentration of propofol.
Topics: Calibration; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Dexmedetomidine; Humans; Limit of Detection; Plasma; Propofol; Tandem Mass Spectrometry; Water | 2018 |
Comparison of Ketamine- Versus Nonketamine-Based Sedation on Delirium and Coma in the Intensive Care Unit.
Topics: Academic Medical Centers; Aged; Coma; Critical Care Outcomes; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Ketamine; Male; Middle Aged; Propofol; Respiration, Artificial; Retrospective Studies; United States | 2020 |
Dexmedetomidine or fentanyl? Cardiovascular stability and analgesia during propofol-ketamine total intravenous anaesthesia in experimental pigs.
Topics: Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Cardiovascular System; Dexmedetomidine; Fentanyl; Infusions, Intravenous; Ketamine; Male; Propofol; Swine | 2018 |
A Comparison of Safety and Efficacy of Dexmedetomidine and Propofol in Children with Autism and Autism Spectrum Disorders Undergoing Magnetic Resonance Imaging.
Topics: Anesthesia, Intravenous; Autism Spectrum Disorder; Child; Child, Preschool; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Hypotension; Magnetic Resonance Imaging; Male; Propofol; Retrospective Studies; Treatment Outcome | 2018 |
Comparison of desflurane and propofol at equipotent doses in combination with a constant rate infusion of dexmedetomidine on global and peripheral perfusion and oxygenation in horses.
Topics: Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Cardiac Output; Desflurane; Dexmedetomidine; Heart Rate; Hemodynamics; Horses; Isoflurane; Ketamine; Oxygen; Perfusion; Propofol; Respiratory Physiological Phenomena; Vascular Resistance | 2018 |
Dexmedetomidine and propofol sedation requirements in an autistic rat model.
Topics: Animals; Animals, Newborn; Autistic Disorder; Dexmedetomidine; Disease Models, Animal; Electroencephalography; Female; Hypnotics and Sedatives; Male; Pregnancy; Propofol; Random Allocation; Rats; Rats, Sprague-Dawley | 2019 |
Low-dose dexmedetomidine as an adjuvant to propofol infusion for children in MRI: A double-cohort study.
Topics: Adolescent; Adult; Anesthetics, Intravenous; Child; Child, Preschool; Cohort Studies; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Infant; Magnetic Resonance Imaging; Male; Propofol; Respiration; Retrospective Studies; Young Adult | 2018 |
Probing the twilight zone of anaesthetic-induced composite consciousness.
Topics: Anesthetics; Awareness; Consciousness; Dexmedetomidine; Propofol | 2018 |
Dreaming and awareness during dexmedetomidine- and propofol-induced unresponsiveness.
Topics: Acoustic Stimulation; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Arousal; Conscious Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Dreams; Healthy Volunteers; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intraoperative Awareness; Male; Memory; Propofol; Psychomotor Performance; Recognition, Psychology; Unconsciousness; Young Adult | 2018 |
Dexmedetomidine facilitates extubation in children who require intubation and respiratory support after airway foreign body retrieval: a case-cohort analysis of 57 cases.
Topics: Airway Extubation; Bronchoscopy; Case-Control Studies; Child, Preschool; Cohort Studies; Cough; Dexmedetomidine; Female; Foreign Bodies; Humans; Hypnotics and Sedatives; Infant; Intubation, Intratracheal; Male; Propofol; Respiration, Artificial; Retrospective Studies | 2018 |
Perioperative Sedation in Mechanically Ventilated Cardiac Surgery Patients With Dexmedetomidine-Based Versus Propofol-Based Regimens.
Topics: Aged; Cardiac Surgical Procedures; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol; Respiration, Artificial; Retrospective Studies | 2019 |
Depth of Propofol Sedation and Postoperative Delirium: The Jury Is Still Out.
Topics: Aged; Anesthesia; Delirium; Dexmedetomidine; Hip Fractures; Humans; Propofol | 2018 |
Altered stimulus representation in rat auditory cortex is not causal for loss of consciousness under general anaesthesia.
Topics: Acoustic Stimulation; Anesthesia, General; Anesthetics, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Auditory Cortex; Consciousness; Dexmedetomidine; Electroencephalography; Female; Hypnotics and Sedatives; Isoflurane; Propofol; Rats, Inbred ACI; Reaction Time; Reflex, Righting | 2018 |
Effects of two levels of partial neuromuscular block with atracurium on the ventilatory response to hypercapnia in anesthetized Beagles.
Topics: Animals; Atracurium; Capnography; Dexmedetomidine; Dogs; Edrophonium; Hypercapnia; Male; Neuromuscular Blockade; Propofol; Respiration; Spirometry; Tidal Volume | 2018 |
Fast-Track Management in Off-Pump Coronary Artery Bypass Grafting: Dexmedetomidine Provides Rapid Extubation and Effective Pain Modulation.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Airway Extubation; Analgesics, Non-Narcotic; Atrial Fibrillation; Coronary Artery Bypass, Off-Pump; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Length of Stay; Male; Middle Aged; Pain, Postoperative; Propofol; Recovery of Function; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome | 2019 |
The Effect of Sedating Agents on Drug-Induced Sleep Endoscopy Findings.
Topics: Adult; Dexmedetomidine; Endoscopy; Epiglottis; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Nose; Oropharynx; Polysomnography; Propofol; Prospective Studies; Sleep; Sleep Apnea, Obstructive; Tongue; Young Adult | 2019 |
Effects From Continuous Infusions of Dexmedetomidine and Propofol on Hemodynamic Stability in Critically Ill Adult Patients With Septic Shock.
Topics: Adult; Aged; Bradycardia; Critical Care; Critical Care Outcomes; Critical Illness; Dexmedetomidine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Hypotension; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Propofol; Retrospective Studies; Shock, Septic | 2020 |
Correcting for repeated outcome measures.
Topics: Child; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Humans; Outcome Assessment, Health Care; Propofol; Tonsillectomy | 2018 |
Dexmedetomidine and midazolam probably result in fewer unexpected movements but more complications than propofol and midazolam in patients undergoing dental procedures under intravenous sedation.
Topics: Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Propofol | 2019 |
A retrospective comparison of propofol to dexmedetomidine for pediatric magnetic resonance imaging sedation in patients with mucopolysaccharidosis type II.
Topics: Airway Obstruction; Anesthesia; Child; Child, Preschool; Deep Sedation; Dexmedetomidine; Hemodynamics; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Male; Mucopolysaccharidosis II; Propofol; Retrospective Studies | 2018 |
[Efficacy of Dexmedetomidine in Monitored Anesthesia Care (MAC) for a Woman with Mitochondrial Encephalomyopathy Associated with Myoclonus].
Topics: Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Dexmedetomidine; Female; Humans; Midazolam; Mitochondrial Encephalomyopathies; Monitoring, Physiologic; Myoclonus; Propofol | 2017 |
Propofol-sparing effect of different concentrations of dexmedetomidine : Comparison of gender differences.
Topics: Adult; Anesthesia; Anesthetics, Intravenous; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol | 2019 |
Pharmacological analysis of dexmedetomidine hydrochloride in pediatric anesthesia during magnetic resonance imaging.
Topics: Anesthesia; Child, Preschool; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Male; Propofol | 2018 |
Effect of dexmedetomidine on postoperative delirium in elderly patients undergoing hip fracture surgery.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Aged, 80 and over; Anesthesia, General; Delirium; Dexmedetomidine; Female; Hip Fractures; Humans; Hypnotics and Sedatives; Incidence; Male; Middle Aged; Neuroprotective Agents; Pain; Postoperative Complications; Propofol | 2018 |
Anesthetic Management for Medialization Laryngoplasty Performed Under Concurrent Dexmedetomidine, Remifentanil, and Propofol Infusions.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Dexmedetomidine; Humans; Hypnotics and Sedatives; Laryngoplasty; Operative Time; Phonation; Propofol; Prosthesis Design; Remifentanil; Retrospective Studies; Treatment Outcome; Vocal Cord Paralysis; Vocal Cords; Voice Disorders; Voice Quality | 2020 |
Effect of Dexmedetomidine Combined Anesthesia on Motor evoked Potentials During Brain Tumor Surgery.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthetics; Brain; Brain Neoplasms; Consciousness Monitors; Dexmedetomidine; Drug Therapy, Combination; Electric Stimulation; Evoked Potentials, Motor; Evoked Potentials, Somatosensory; Female; Humans; Intraoperative Neurophysiological Monitoring; Male; Middle Aged; Neuroprotective Agents; Neurosurgical Procedures; Propofol; Remifentanil; Retrospective Studies | 2019 |
The efficacy of drug induced sleep endoscopy using multimodality monitoring system.
Topics: Adult; Aged; Dexmedetomidine; Electrocardiography; Endoscopy; Female; Humans; Male; Middle Aged; Polysomnography; Propofol; Randomized Controlled Trials as Topic; Sleep Apnea, Obstructive; Snoring | 2018 |
Comparison of Cognitive Impairments After Intensive Care Unit Sedation Using Dexmedetomidine and Propofol Among Older Patients.
Topics: Aged; Aged, 80 and over; Anesthesia; Cognition; Cognitive Dysfunction; Cohort Studies; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Propofol; Random Allocation | 2019 |
Comparison of genioglossus muscle activity and efficiency of dexmedetomidine or propofol during drug-induced sleep endoscopy in patients with obstructive sleep apnea/hypopnea syndrome.
Topics: Adult; Aged; Dexmedetomidine; Electromyography; Endoscopy; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Muscle Strength; Muscle, Skeletal; Polysomnography; Propofol; Prospective Studies; Respiration; Sleep Apnea, Obstructive; Tongue; Treatment Outcome | 2019 |
Cellular stress and AMPK links metformin and diverse compounds with accelerated emergence from anesthesia and potential recovery from disorders of consciousness.
Topics: AMP-Activated Protein Kinases; Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Brain Mapping; Calcium; Cell Lineage; Cell Proliferation; Consciousness; Consciousness Disorders; Dexmedetomidine; Humans; Isoflurane; Ketamine; Learning; Long-Term Potentiation; Memory; Metformin; Midazolam; Models, Neurological; Nicotine; Propofol; Reactive Oxygen Species; Sevoflurane; Unconsciousness | 2019 |
Maternal and neonatal wellbeing during elective C-section induced with a combination of propofol and dexmedetomidine: How effective is the placental barrier in dogs?
Topics: Anesthetics, Intravenous; Animals; Blood-Brain Barrier; Cesarean Section; Dexmedetomidine; Dogs; Female; Male; Maternal-Fetal Exchange; Placenta; Pregnancy; Propofol | 2019 |
Assessing the sedation effect of dexmedetomidine during hysteroscopic surgery.
Topics: Conscious Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Hysteroscopy; Pregnancy; Propofol | 2019 |
Authors' reply to Dr. Bailong's commentary: Assessing the sedation effect of dexmedetomidine during hysteroscopic surgery.
Topics: Conscious Sedation; Dexmedetomidine; Drugs, Chinese Herbal; Female; Humans; Hypnotics and Sedatives; Hysteroscopy; Pregnancy; Propofol | 2019 |
On the Right Track, Finally?
Topics: Cross-Over Studies; Dexmedetomidine; Humans; Norepinephrine; Propofol; Shock, Septic | 2019 |
The authors reply.
Topics: Cross-Over Studies; Dexmedetomidine; Humans; Norepinephrine; Propofol; Shock, Septic | 2019 |
A Common Neuroendocrine Substrate for Diverse General Anesthetics and Sleep.
Topics: Anesthesia, General; Anesthetics, General; Animals; Dexmedetomidine; Electroencephalography; Electromyography; Electrophysiological Phenomena; Hypnotics and Sedatives; Hypothalamus; Isoflurane; Ketamine; Mice; Neuroendocrine Cells; Neurons; Optogenetics; Patch-Clamp Techniques; Propofol; Proto-Oncogene Proteins c-fos; Sleep; Sleep, Slow-Wave; Supraoptic Nucleus | 2019 |
A national survey on routines regarding sedation in Swedish intensive care units.
Topics: Anesthesia; Confidence Intervals; Conscious Sedation; Dexmedetomidine; Diagnostic Tests, Routine; Female; Health Care Surveys; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Propofol; Quality Improvement; Registries; Statistics, Nonparametric; Sweden | 2019 |
Differential effects of propofol and dexmedetomidine on neuroinflammation induced by systemic endotoxin lipopolysaccharides in adult mice.
Topics: Animals; Antioxidants; Brain; Cognition Disorders; Dexmedetomidine; Hippocampus; Hypnotics and Sedatives; Inflammation; Interleukin-1beta; Lipopolysaccharides; Male; Maze Learning; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Propofol; Rotarod Performance Test; Tumor Necrosis Factor-alpha | 2019 |
Current practice and perceptions regarding pain, agitation and delirium management in patients receiving venovenous extracorporeal membrane oxygenation.
Topics: Adult; Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Attitude of Health Personnel; Benzodiazepines; Critical Care; Cross-Sectional Studies; Deep Sedation; Delirium; Dexmedetomidine; Extracorporeal Membrane Oxygenation; Fentanyl; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pain; Perception; Professional Practice; Propofol; Psychomotor Agitation; Respiratory Insufficiency | 2019 |
Use of Dexmedetomidine for Deep Sedation and Reduction of Vasopressor Requirement?
Topics: Conscious Sedation; Cross-Over Studies; Deep Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Norepinephrine; Propofol; Shock, Septic | 2019 |
The authors reply.
Topics: Cross-Over Studies; Dexmedetomidine; Humans; Norepinephrine; Propofol; Shock, Septic | 2019 |
Intravenous Acetaminophen for Postoperative Delirium.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Delirium; Dexmedetomidine; Humans; Propofol | 2019 |
Intravenous Acetaminophen for Postoperative Delirium-Reply.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Delirium; Dexmedetomidine; Humans; Propofol | 2019 |
Opioid free anesthesia: is it too early to bid adieu?
Topics: Analgesics, Opioid; Anesthesia, Intravenous; Cholecystectomy, Laparoscopic; Dexmedetomidine; Lidocaine; Propofol; Prospective Studies | 2019 |
In reference to Dexmedetomidine versus propofol at different sedation depths during drug-induced sleep endoscopy: A randomized trial.
Topics: Anesthesia; Dexmedetomidine; Endoscopy; Hypnotics and Sedatives; Propofol | 2020 |
Incidence of Rebound Hypertension after Discontinuation of Dexmedetomidine.
Topics: Critical Care; Dexmedetomidine; Drug Administration Schedule; Female; Humans; Hypertension; Hypnotics and Sedatives; Incidence; Infusions, Intravenous; Intensive Care Units; Male; Midazolam; Middle Aged; Outcome and Process Assessment, Health Care; Propofol; Retrospective Studies; Time Factors; United States; Withholding Treatment | 2019 |
Comment on "Propofol Versus Dexmedetomidine for Procedural Sedation in a Pediatric Population".
Topics: Child; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol | 2019 |
Dexmedetomidine and the Upper Airway: Not as Simple as We Hoped.
Topics: Anesthesia; Cross-Over Studies; Dexmedetomidine; Hypnotics and Sedatives; Propofol | 2019 |
In response to Dexmedetomidine versus propofol at different sedation depths during drug-induced sleep endoscopy: A randomized trial.
Topics: Anesthesia; Dexmedetomidine; Endoscopy; Hypnotics and Sedatives; Propofol | 2020 |
Use of Propofol Plus Dexmedetomidine in Patients Experiencing Severe Alcohol Withdrawal in the Intensive Care Unit.
Topics: Alcoholism; Bradycardia; Critical Care; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Hypotension; Intensive Care Units; Length of Stay; Male; Middle Aged; Propofol; Retrospective Studies; Substance Withdrawal Syndrome | 2020 |
Adverse Hemodynamic Events Associated With Concomitant Dexmedetomidine and Propofol for Sedation in Mechanically Ventilated ICU Patients.
Topics: Adult; Dexmedetomidine; Hemodynamics; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Respiration, Artificial; Retrospective Studies | 2020 |
Comparison of Propofol and Dexmedetomidine Sedation in Septic Shock.
Topics: Conscious Sedation; Cross-Over Studies; Dexmedetomidine; Humans; Hypnotics and Sedatives; Norepinephrine; Propofol; Shock, Septic | 2019 |
The authors reply.
Topics: Cross-Over Studies; Dexmedetomidine; Humans; Norepinephrine; Propofol; Shock, Septic | 2019 |
Interpretation Woes of Bispectral Index-Based Closed-Looped Anesthesia Delivery Systems.
Topics: Anesthesia; Anesthetics, Intravenous; Dexmedetomidine; Propofol | 2019 |
In Response.
Topics: Anesthesia; Anesthesiology; Dexmedetomidine; Propofol; Research Design | 2019 |
Sedation with midazolam worsens the diaphragm function than dexmedetomidine and propofol during mechanical ventilation in rats.
Topics: Anesthesia; Animals; Antioxidants; Autophagy; Biomechanical Phenomena; Cell Line; Dexmedetomidine; Diaphragm; Male; Midazolam; Muscle Contraction; Oxidants; Oxidative Stress; Propofol; Proteasome Endopeptidase Complex; Proteolysis; Rats, Wistar; Respiration, Artificial; Vital Signs | 2020 |
Feasibility of non-intubated anesthesia and regional block for thoracoscopic surgery under spontaneous respiration: a prospective cohort study.
Topics: Adolescent; Adult; Anesthesia, General; Blood Pressure; Dexmedetomidine; Feasibility Studies; Female; Heart Rate; Humans; Laryngeal Masks; Male; Middle Aged; Nerve Block; Propofol; Prospective Studies; Remifentanil; Thoracoscopy; Young Adult | 2020 |
Sedation selection to reduce delirium risk: Why dexmedetomidine may be a better choice.
Topics: Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol | 2020 |
Inhibitory concentration of propofol in combination with dexmedetomidine during microelectrode recording for deep brain stimulator insertion surgeries under general anesthesia.
Topics: Aged; Anesthesia, General; Deep Brain Stimulation; Dexmedetomidine; Female; Humans; Male; Microelectrodes; Middle Aged; Propofol; Prospective Studies | 2020 |
Bilateral erector spinae plane block for scoliosis surgery: Case series.
Topics: Adolescent; Anesthetics, Intravenous; Anesthetics, Local; Child; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Nerve Block; Pain, Postoperative; Paraspinal Muscles; Propofol; Ropivacaine; Scoliosis | 2020 |
Dexmedetomidine protects against acute kidney injury in patients with septic shock.
Topics: Acute Kidney Injury; Adult; Aged; Analgesics, Non-Narcotic; China; Cohort Studies; Dexmedetomidine; Female; Humans; Male; Middle Aged; Propofol; Respiration, Artificial; Shock, Septic | 2020 |
The effect of repetitive exposure to intravenous anesthetic agents on the immunity in mice.
Topics: Adaptive Immunity; Anesthetics, Intravenous; Animals; CD4-Positive T-Lymphocytes; Dexmedetomidine; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Kidney; Liver; Male; Mice; Mice, Inbred BALB C; Midazolam; Propofol | 2020 |
Dexmedetomidine Sedation and Airway Collapsibility: Comment.
Topics: Anesthesia; Cross-Over Studies; Dexmedetomidine; Hypnotics and Sedatives; Propofol | 2020 |
Dexmedetomidine Sedation and Airway Collapsibility: Reply.
Topics: Anesthesia; Cross-Over Studies; Dexmedetomidine; Hypnotics and Sedatives; Propofol | 2020 |
Cost analysis of dexmedetomidine versus propofol during the implantation of a neurostimulator.
Topics: Conscious Sedation; Dexmedetomidine; Hypnotics and Sedatives; Propofol | 2020 |
The Effectiveness of Low-dose Dexmedetomidine Infusion in Sedative Flexible Bronchoscopy: A Retrospective Analysis.
Topics: Aged; Bronchoscopy; Conscious Sedation; Dexmedetomidine; Drug Therapy, Combination; Female; Fentanyl; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Propofol; Retrospective Studies | 2020 |
Ketamine-dexmedetomidine combination and controlled mild hypothermia for the treatment of long-lasting and super-refractory status epilepticus in 3 dogs suffering from idiopathic epilepsy.
Topics: Analgesics; Anesthesia, General; Animals; Body Temperature; Dexmedetomidine; Dog Diseases; Dogs; Epilepsy; Female; Hypnotics and Sedatives; Hypothermia, Induced; Ketamine; Male; Propofol; Status Epilepticus | 2020 |
Neuroanesthesia Guidelines for Optimizing Transcranial Motor Evoked Potential Neuromonitoring During Deformity and Complex Spinal Surgery: A Delphi Consensus Study.
Topics: Anesthesia, General; Anesthetics, Intravenous; Consensus; Delphi Technique; Dexmedetomidine; Evoked Potentials, Motor; Humans; Intraoperative Neurophysiological Monitoring; Ketamine; Lidocaine; Neurosurgical Procedures; Practice Guidelines as Topic; Propofol; Spinal Cord; Spinal Curvatures | 2020 |
Cerebral autoregulation after aneurysmal subarachnoid haemorrhage. A preliminary study comparing dexmedetomidine to propofol and/or midazolam.
Topics: Cerebrovascular Circulation; Dexmedetomidine; Homeostasis; Humans; Midazolam; Propofol; Subarachnoid Hemorrhage | 2020 |
Anesthetic agents affect urodynamic parameters and anesthetic depth at doses necessary to facilitate preclinical testing in felines.
Topics: Anesthesia Recovery Period; Anesthetics; Animals; Cats; Chloralose; Dexmedetomidine; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; Heart Rate; Isoflurane; Male; Models, Animal; Muscle Contraction; Muscle, Smooth; Pregnanediones; Pressure; Propofol; Urinary Bladder; Urodynamics | 2020 |
Effects of propofol and dexmedetomidine with and without remifentanil on serum cytokine concentrations in healthy volunteers: a post hoc analysis.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Cytokines; Dexmedetomidine; Female; Healthy Volunteers; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol; Reference Values; Remifentanil; Young Adult | 2020 |
Weaning From Exogenous Sedation in the Era of COVID-19 Infection: Recommendations for Sedation and Its Discontinuation.
Topics: Adult; Analgesics, Opioid; Benzodiazepines; Betacoronavirus; Coronavirus Infections; COVID-19; Deprescriptions; Dexmedetomidine; Emergence Delirium; Humans; Hypnotics and Sedatives; Male; Neurologic Examination; Pandemics; Pneumonia, Viral; Practice Guidelines as Topic; Propofol; Respiration, Artificial; SARS-CoV-2; Substance Withdrawal Syndrome | 2020 |
Dexmedetomidine and Mortality From Sepsis Requiring Mechanical Ventilation: A Japanese Nationwide Retrospective Cohort Study.
Topics: Adult; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Japan; Propofol; Respiration, Artificial; Retrospective Studies; Sepsis | 2021 |
Effectiveness of Quetiapine as a Sedative Adjunct in Mechanically Ventilated Adults Without Delirium.
Topics: Adjuvants, Pharmaceutic; Adult; Analgesics, Opioid; Benzodiazepines; Cohort Studies; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Pain; Propofol; Quetiapine Fumarate; Respiration, Artificial; Retrospective Studies | 2021 |
Anesthetic Management of Awake Craniotomy for Resection of the Language and Motor Cortex Vascular Malformations.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Intravenous; Brain Neoplasms; Broca Area; Cerebral Angiography; Computed Tomography Angiography; Craniotomy; Deep Sedation; Dexmedetomidine; Female; Fentanyl; Hemangioma, Cavernous, Central Nervous System; Humans; Hypnotics and Sedatives; Intracranial Arteriovenous Malformations; Male; Middle Aged; Motor Cortex; Nerve Block; Neurosurgical Procedures; Propofol; Remifentanil; Wakefulness; Wernicke Area; Young Adult | 2020 |
DEXmedetomidine compared to PROpofol in NEurocritical Care [DEXPRONE]: A multicenter retrospective evaluation of clinical utility and safety.
Topics: Adult; Aged; Bradycardia; Critical Care; Critical Illness; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Hypotension; Intensive Care Units; Male; Middle Aged; Propofol; Respiration, Artificial; Retrospective Studies; Treatment Outcome | 2020 |
Alpha band frontal connectivity is a state-specific electroencephalographic correlate of unresponsiveness during exposure to dexmedetomidine and propofol.
Topics: Adult; Dexmedetomidine; Dose-Response Relationship, Drug; Electroencephalography; Frontal Lobe; Humans; Male; Prefrontal Cortex; Propofol | 2020 |
Clinical and economic impact of the use of dexmedetomidine for sedation in the intensive care unit compared to propofol.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Intravenous; Cost-Benefit Analysis; Critical Care; Dexmedetomidine; Drug Costs; Drugs, Generic; Female; Hospital Costs; Humans; Hypnotics and Sedatives; Length of Stay; Male; Middle Aged; Propofol; Respiration, Artificial; Retrospective Studies | 2020 |
Propofol versus dexmedetomidine during drug-induced sleep endoscopy (DISE) for pediatric obstructive sleep apnea.
Topics: Adolescent; Airway Obstruction; Child; Child, Preschool; Dexmedetomidine; Endoscopy; Female; Humans; Infant; Male; Propofol; Retrospective Studies; Sleep; Sleep Apnea, Obstructive | 2021 |
Effect of sedation with dexmedetomidine or propofol on gastrointestinal motility in lipopolysaccharide-induced endotoxemic mice.
Topics: Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Endotoxemia; Gastric Emptying; Gastrointestinal Motility; Hypnotics and Sedatives; Inflammation Mediators; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Propofol | 2020 |
Dexmedetomidine Is an Equal Cost Alternative to Propofol in Transcatheter Aortic Valve Replacement, With Equivalent In-Hospital and 30-Day Outcomes.
Topics: Aortic Valve; Aortic Valve Stenosis; Dexmedetomidine; Hospital Mortality; Hospitals; Humans; Propofol; Retrospective Studies; Risk Factors; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2021 |
Propofol but not dexmedetomidine produce locomotor sensitization via nitric oxide in rats.
Topics: Animals; Central Nervous System Stimulants; Dexmedetomidine; Dose-Response Relationship, Drug; Locomotion; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Propofol; Rats; Rats, Wistar | 2021 |
The Economics of Transcatheter Aortic Valve Replacement and the Anesthesiologist.
Topics: Anesthesiologists; Aortic Valve; Aortic Valve Stenosis; Dexmedetomidine; Hospitals; Humans; Propofol; Transcatheter Aortic Valve Replacement | 2021 |
Foundations of Human Consciousness: Imaging the Twilight Zone.
Topics: Adult; Brain; Consciousness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Male; Positron-Emission Tomography; Propofol; Sleep Deprivation; Sleep, REM; Unconsciousness; Wakefulness | 2021 |
Propofol shows less negative effects on cognitive performances than dexmedetomidine in elderly intensive care unit patients.
Topics: Aged; Cognition; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Prospective Studies; Quality of Life; Respiration, Artificial | 2021 |
A Case Report of Sedation Strategy for a Patient With Coronavirus Disease 2019 Supported by Extracorporeal Membrane Oxygenation After Cesarean Section.
Topics: Cesarean Section; Combined Modality Therapy; COVID-19; Dexmedetomidine; Extracorporeal Membrane Oxygenation; Female; Fluid Therapy; Humans; Hypnotics and Sedatives; Midazolam; Monitoring, Physiologic; Nutritional Support; Pregnancy; Propofol; Respiration, Artificial; SARS-CoV-2 | 2021 |
Comparison between dexmedetomidine and acepromazine in combination with methadone for premedication in brachycephalic dogs undergoing surgery for brachycephalic obstructive airway syndrome.
Topics: Acepromazine; Animals; Dexmedetomidine; Dogs; Methadone; Premedication; Propofol | 2021 |
Remifentanil provides an increased proportion of time under light sedation than fentanyl when combined with dexmedetomidine for mechanical ventilation.
Topics: Adult; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Piperidines; Propofol; Remifentanil; Respiration, Artificial; Retrospective Studies | 2021 |
Effect of supplemental dexmedetomidine in interventional embolism on cerebral oxygen metabolism in patients with intracranial aneurysms.
Topics: Dexmedetomidine; Embolism; Female; Humans; Intracranial Aneurysm; Male; Oxygen; Propofol | 2021 |
Dexmedetomidine Reverses Postoperative Spatial Memory Deficit by Targeting Surf1 and Cytochrome c.
Topics: Animals; Cytochromes c; Dexmedetomidine; Hippocampus; Male; Memory Disorders; Propofol; Rats; Rats, Sprague-Dawley | 2021 |
Current Evidence Demonstrates a Significant Reduction in the Incidence of Delirium With Postoperative Dexmedetomidine Versus Propofol Sedation.
Topics: Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Incidence; Propofol | 2022 |
Association of dexmedetomidine with recovery room and hospital discharge times: A retrospective cohort analysis.
Topics: Anesthesia Recovery Period; Anesthetics, Intravenous; Child; Dexmedetomidine; Hospitals; Humans; Patient Discharge; Propofol; Recovery Room; Retrospective Studies | 2021 |
Dexmedetomidine versus Propofol Sedation for Prevention of Postoperative Delirium: Clarifications Required [Letter].
Topics: Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol | 2021 |
Fetal Bladder Rupture as a Complication of Adjunctive Therapy in Severe Maternal SARS-CoV-2 Pneumonia.
Topics: Adult; Analgesics, Opioid; COVID-19; Dexmedetomidine; Female; Fentanyl; Humans; Midazolam; Pregnancy; Propofol; SARS-CoV-2; Urinary Bladder | 2022 |
Effect of Sedatives on In-hospital and Long-term Mortality of Critically Ill Patients Requiring Extended Mechanical Ventilation for ≥ 48 Hours.
Topics: Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critical Illness; Dexmedetomidine; Female; Hospital Mortality; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Male; Middle Aged; Propofol; Republic of Korea; Respiration, Artificial; Retrospective Studies; Time Factors | 2021 |
The Influence of Different Dexmedetomidine Doses on Cognitive Function at Early Period of Patients Undergoing Laparoscopic Extensive Total Hysterectomy.
Topics: Child; Cognition; Dexmedetomidine; Female; Humans; Hysterectomy; Laparoscopy; Propofol | 2021 |
Hemodynamic Effects of Ketamine Compared With Propofol or Dexmedetomidine as Continuous ICU Sedation.
Topics: Adult; Bradycardia; Dexmedetomidine; Hemodynamics; Humans; Hypnotics and Sedatives; Hypotension; Intensive Care Units; Ketamine; Propofol; Retrospective Studies | 2022 |
Dexmedetomidine attenuates propofol-induced apoptosis of neonatal hippocampal astrocytes by inhibiting the Bcl2l1 signalling pathway.
Topics: Animals; Apoptosis; Astrocytes; bcl-X Protein; Dexmedetomidine; Hippocampus; MicroRNAs; Propofol; Rats; Rats, Sprague-Dawley | 2021 |
A comparison of GABA-ergic (propofol) and non-GABA-ergic (dexmedetomidine) sedation on visual and motor cortical oscillations, using magnetoencephalography.
Topics: Adult; Brain Waves; Conscious Sedation; Consciousness; Cross-Over Studies; Dexmedetomidine; Humans; Hypnotics and Sedatives; Magnetoencephalography; Male; Motor Cortex; Movement; Propofol; Wakefulness; Young Adult | 2021 |
On no man's land: Subjective experiences during unresponsive and responsive sedative states induced by four different anesthetic agents.
Topics: Anesthetics; Dexmedetomidine; Humans; Hypnotics and Sedatives; Male; Propofol; Sevoflurane | 2021 |
The influence of anesthesia and surgery on fear extinction.
Topics: Anesthesia; Anesthetics; Animals; Anti-Inflammatory Agents; Dexmedetomidine; Extinction, Psychological; Fear; Mental Recall; Mice; Propofol; Sevoflurane; Stress Disorders, Post-Traumatic; Surgical Procedures, Operative | 2022 |
Comparative effects of dexmedetomidine and propofol on brain and lung damage in experimental acute ischemic stroke.
Topics: Animals; Brain; Brain Ischemia; Dexmedetomidine; Disease Models, Animal; Endothelial Cells; Hypnotics and Sedatives; Interleukin-1beta; Interleukin-6; Ischemic Stroke; Lung; Macrophages, Alveolar; Male; Propofol; Rats; Rats, Wistar; Thiopental; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2021 |
Comparing the impact on the prognosis of acute myocardial infarction critical patients of using midazolam, propofol, and dexmedetomidine for sedation.
Topics: Aged; Aged, 80 and over; Coronary Care Units; Critical Illness; Databases, Factual; Dexmedetomidine; Female; Hospital Mortality; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Myocardial Infarction; Propofol; Respiration, Artificial; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome | 2021 |
Effects of different sedatives/analgesics on stress responses in patients undergoing craniotomy and bone flap decompression.
Topics: Analgesics; Craniotomy; Decompression; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol | 2021 |
The effect of Propofol versus Dexmedetomidine as anesthetic agents for oocyte pick-up on in vitro fertilization (IVF) outcomes.
Topics: Animals; Dexmedetomidine; Female; Fertilization in Vitro; Oocyte Retrieval; Oocytes; Propofol; Rats; Rats, Sprague-Dawley | 2021 |
Recovery characteristics and parental satisfaction in pediatric procedural sedation.
Topics: Child; Conscious Sedation; Dexmedetomidine; Hallucinations; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Parents; Personal Satisfaction; Propofol; Respiratory Distress Syndrome; Sleepiness; Vomiting | 2022 |
Cerebrospinal fluid metabolic profiling reveals divergent modulation of pentose phosphate pathway by midazolam, propofol and dexmedetomidine in patients with subarachnoid hemorrhage: a cohort study.
Topics: Aged; Cohort Studies; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Pentose Phosphate Pathway; Propofol; Psychomotor Agitation; Subarachnoid Hemorrhage | 2022 |
Distinct EEG signatures differentiate unconsciousness and disconnection during anaesthesia and sleep.
Topics: Anesthesia; Consciousness; Dexmedetomidine; Electroencephalography; Humans; Hypnotics and Sedatives; Propofol; Sleep; Unconsciousness | 2022 |
Comparison between dexmedetomidine and propofol on outcomes after coronary artery bypass graft surgery: a retrospective study.
Topics: Aged; China; Cohort Studies; Coronary Artery Bypass; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Length of Stay; Male; Middle Aged; Postoperative Complications; Propofol; Respiration, Artificial; Retrospective Studies | 2022 |
Dexmedetomidine Versus Propofol for Sedation After Adult Cardiac Surgery: A Trial Sequential Analysis.
Topics: Adult; Cardiac Surgical Procedures; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol | 2022 |
Dexmedetomidine reduces propofol-induced hippocampal neuron injury by modulating the miR-377-5p/Arc pathway.
Topics: Animals; Apoptosis; Cytoskeletal Proteins; Dexmedetomidine; Hippocampus; Mice; MicroRNAs; Nerve Tissue Proteins; Neurons; Propofol | 2022 |
Total Intravenous Anesthesia With Dexmedetomidine for Hemodynamic Stability and Enhanced Recovery in Facial Aesthetic Surgery.
Topics: Adrenergic Agonists; Analgesics; Anesthesia, General; Anesthesia, Intravenous; Anti-Anxiety Agents; Dexmedetomidine; Hemodynamics; Humans; Hypnotics and Sedatives; Propofol; Retrospective Studies; Surgery, Plastic | 2022 |
Effects of acepromazine and dexmedetomidine, followed by propofol induction and maintenance with isoflurane anaesthesia, on the microcirculation of Beagle dogs evaluated by sidestream dark field imaging: an experimental trial.
Topics: Acepromazine; Anesthesia; Animals; Cross-Over Studies; Dexmedetomidine; Dogs; Hypnotics and Sedatives; Isoflurane; Microcirculation; Propofol | 2022 |
Comparison of Standard-Dose Versus High-Dose Dexmedetomidine in Extracorporeal Membrane Oxygenation.
Topics: Adult; Analgesics; Bradycardia; Dexmedetomidine; Extracorporeal Membrane Oxygenation; Humans; Hypnotics and Sedatives; Hypotension; Propofol; Retrospective Studies | 2023 |
Intrathecal dexmedetomidine attenuates mechanical allodynia through the downregulation of brain-derived neurotrophic factor in a mild traumatic brain injury rat model.
Topics: Animals; Brain Concussion; Brain-Derived Neurotrophic Factor; Dexmedetomidine; Down-Regulation; Hyperalgesia; Propofol; Rats; Rats, Sprague-Dawley | 2023 |
Comparison of the effect of sedation and general anesthesia on pattern and flash visual evoked potentials in normal dogs.
Topics: Anesthesia, General; Animals; Butorphanol; Dexmedetomidine; Dogs; Evoked Potentials, Visual; Propofol | 2022 |
Effects of propofol and dexmedetomidine on carnitine metabolism in normal human bronchial epithelial cells.
Topics: Carnitine; Dexmedetomidine; Epithelial Cells; Humans; Propofol | 2023 |
Dexmedetomidine and Propofol at End of Life in Pediatric Oncology: Trends in Palliative Sedation Therapy.
Topics: Child; Death; Dexmedetomidine; Humans; Neoplasms; Pain; Palliative Care; Propofol; Prospective Studies; Terminal Care | 2023 |
Ultrasound-guided bilateral erector spinae plane block in dogs undergoing sternotomies anaesthetised with propofol-dexmedetomidine continuous infusion.
Topics: Animals; Dexmedetomidine; Dog Diseases; Dogs; Nerve Block; Pain, Postoperative; Propofol; Sternotomy; Ultrasonography, Interventional | 2022 |
Effect of Dexmedetomidine Compared to Remifentanil During Bariatric Surgery on Postoperative Nausea and Vomiting: a Retrospective Study.
Topics: Adult; Analgesics; Analgesics, Opioid; Antiemetics; Bariatric Surgery; Dexmedetomidine; Double-Blind Method; Humans; Obesity, Morbid; Pain, Postoperative; Postoperative Nausea and Vomiting; Propofol; Remifentanil; Retrospective Studies | 2022 |
Comparison of the performance of phase lag entropy and bispectral index for monitoring the depth of sedation under dexmedetomidine sedation: A prospective, observational, and non-inferiority trial.
Topics: Anesthesia, Spinal; Dexmedetomidine; Electroencephalography; Entropy; Humans; Hypnotics and Sedatives; Propofol; Prospective Studies | 2022 |
Low-dose adjuvant dexmedetomidine did not decrease propofol sedation requirements in children undergoing gastrointestinal endoscopy.
Topics: Anesthesia; Child; Cohort Studies; Dexmedetomidine; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedatives; Hypotension; Propofol; Retrospective Studies | 2022 |
Post-cardiac arrest Sedation Promotes Electroencephalographic Slow-wave Activity and Improves Survival in a Mouse Model of Cardiac Arrest.
Topics: Animals; Cardiopulmonary Resuscitation; Dexmedetomidine; Disease Models, Animal; Electroencephalography; Female; Heart Arrest; Hyperemia; Hypothermia; Hypothermia, Induced; Male; Mice; Mice, Inbred C57BL; Propofol | 2022 |
Pediatric Sedation/Anesthesia for MRI: Results From the Pediatric Sedation Research Consortium.
Topics: Anesthesia; Child; Child, Preschool; Dexmedetomidine; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Propofol; Retrospective Studies | 2023 |
Effect of sedatives or anesthetics on the measurement of resting brain function in common marmosets.
Topics: Anesthetics; Animals; Brain; Callithrix; Dexmedetomidine; Hypnotics and Sedatives; Isoflurane; Midazolam; Propofol; Sevoflurane | 2023 |
Effects of Dexmedetomidine and Propofol on Postoperative Analgesia and the Cellular Immune Function of Patients Undergoing Radical Gastrectomy for Gastric Cancer.
Topics: Analgesia; Analgesics; Dexmedetomidine; Gastrectomy; Humans; Immunity; Pain, Postoperative; Propofol; Stomach Neoplasms | 2022 |
Effect of Parecoxib Sodium Combined with Dexmedetomidine on Analgesia and Postoperative Pain of Patients Undergoing Hysteromyomectomy.
Topics: Analgesia; Dexmedetomidine; Humans; Hydrocortisone; Melatonin; Pain, Postoperative; Propofol; Remifentanil | 2022 |
Performing real time neuropsychological testing during awake craniotomy: are dexmedetomidine or propofol the same? A preliminary report.
Topics: Brain Neoplasms; Craniotomy; Dexmedetomidine; Humans; Hypnotics and Sedatives; Neuropsychological Tests; Propofol; Retrospective Studies; Wakefulness | 2022 |
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sedatives; Lorazepam; Morphine; Pain; Propofol; Retrospective Studies; Tracheotomy; Ventilators, Mechanical | 2022 |
Dexmedetomidine and Propofol Sedation in Critically Ill Patients: How Much Is Too Much?
Topics: Cohort Studies; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol | 2023 |
Evaluation of patient state index, bispectral index, and entropy during drug induced sleep endoscopy with dexmedetomidine.
Topics: Conscious Sedation; Dexmedetomidine; Electroencephalography; Endoscopy; Entropy; Humans; Hypnotics and Sedatives; Propofol; Sleep | 2023 |
Use of Dexmedetomidine in Conscious Sedation for Oesophageal Stent Placement in a High-Risk Patient.
Topics: Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol; Stents | 2023 |
A 67-Year-Old Woman With Fluctuating Hypertension and Hypotension After Elective Surgery.
Topics: Aged; Dexmedetomidine; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Hypotension; Neuromuscular Blockade; Propofol | 2023 |
Effect of Dexmedetomidine versus Propofol on Intraoperative Seizure Onset During Awake Craniotomy: A Retrospective Study.
Topics: Adult; Craniotomy; Dexmedetomidine; Epilepsy; Humans; Hypnotics and Sedatives; Propofol; Retrospective Studies; Seizures; Wakefulness | 2023 |
Comparison of cytotoxic, reactive oxygen species (ROS) and apoptotic effects of propofol, thiopental and dexmedetomidine on liver cells at accumulative doses (AML12).
Topics: Anesthesia, General; Antineoplastic Agents; Dexmedetomidine; Humans; Hypnotics and Sedatives; Liver; Propofol; Reactive Oxygen Species; Thiopental | 2023 |
Dexmedetomidine for cancer surgery: A short-term infusion with long-term benefits. Or just another smoking mirror?
Topics: Dexmedetomidine; Humans; Hypnotics and Sedatives; Neoplasms; Propofol; Smoking | 2023 |
Dexmedetomidine attenuates postoperative spatial memory impairment after surgery by reducing cytochrome C.
Topics: Animals; Cytochromes c; Dexmedetomidine; Hippocampus; Humans; Male; Memory Disorders; Propofol; Rats; Rats, Sprague-Dawley; Spatial Memory | 2023 |
Dexmedetomidine alleviates propofol-induced pyroptosis of hippocampal neurons through NLRP3 inflammasome pathway.
Topics: Caspase 1; Dexmedetomidine; Inflammasomes; Interleukin-18; NLR Family, Pyrin Domain-Containing 3 Protein; Propofol | 2023 |
Oestrous cycle affects emergence from anaesthesia with dexmedetomidine, but not propofol, isoflurane, or sevoflurane, in female rats.
Topics: Anesthesia, General; Animals; Dexmedetomidine; Estradiol; Female; Gases; Isoflurane; Male; Progesterone; Propofol; Rats; Rats, Sprague-Dawley; Sevoflurane | 2023 |
Successful management of suspected propofol dependence with phenobarbital in an adult patient with COVID-19.
Topics: Adult; COVID-19; Dexmedetomidine; Fentanyl; Humans; Hypertension; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Phenobarbital; Propofol | 2023 |
Dexmedetomidine alleviates propofol-induced neural injury in developing rats.
Topics: Anesthetics, Intravenous; Animals; Child; Dexmedetomidine; Hippocampus; Humans; Propofol; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley | 2023 |
The risks of sedation and pain control during burn resuscitation: Increased opioids lead to over-resuscitation and hypotension.
Topics: Adult; Analgesics, Opioid; Benzodiazepines; Burns; Dexmedetomidine; Fluid Therapy; Humans; Hypnotics and Sedatives; Hypotension; Middle Aged; Pain; Pain Management; Propofol; Resuscitation; Retrospective Studies | 2023 |