dexmedetomidine has been researched along with prazosin in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (61.11) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Eglen, RM; MacLennan, SJ; Martin, GR; Martin, RS; Reynen, PH | 1 |
| Eglen, RM; MacLennan, SJ; Martin, GR; Reynen, PH | 1 |
| Lassila, R; Mustonen, P; Savola, J | 1 |
| Adachi, YU; Satoh, T; Taoda, M; Uchihashi, Y; Vizi, ES; Watanabe, K | 1 |
| Hopwood, SE; Stamford, JA | 1 |
| Fotopoulos, A; Johnson, EO; Konstandi, M; Kostakis, D; Lang, MA; Marselos, M | 1 |
| Ahsan, MR; Lin, Y; Quartermain, D; Stone, EA | 1 |
| Adamidis, K; Harkitis, P; Johnson, EO; Konstandi, M; Kostakis, D; Lang, MA; Marselos, M | 1 |
| Gul, H; Seyrek, M; Ulusoy, HB; Yildirim, V; Yildiz, O | 1 |
| Higuchi, H; Kohjitani, A; Maeda, S; Miyawaki, T; Shimada, M; Yoshitomi, T | 1 |
| Man, RY; Ng, KF; Vanhoutte, PM; Wong, ES | 1 |
| Amodeo, FS; Brummett, CM; Hong, EK; Janda, AM; Lydic, R | 1 |
| Acheson, AG; Dashwood, MR; Eames, T; Gruss, H; Henry, Y; Rayment, SJ; Scholefield, JH; Simpson, JA; Wilson, VG | 1 |
| Cui, D; Gao, Y; Han, H; Li, Y; Sun, M; Yang, J; Zhao, G; Zou, J | 1 |
| Eguchi, R; Kitano, T; Okamatsu-Ogura, Y; Otsuguro, KI; Yamaguchi, S | 1 |
| Ahn, SH; Bae, SI; Hwang, Y; Kim, JY; Kim, M; Kwon, SC; Lee, SH; Ok, SH; Park, KE; Sohn, JT | 1 |
1 review(s) available for dexmedetomidine and prazosin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
17 other study(ies) available for dexmedetomidine and prazosin
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using extracellular acidification rate changes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Brimonidine Tartrate; Cell Line; Cricetinae; Dexmedetomidine; Dose-Response Relationship, Drug; Doxazosin; Gene Expression; Humans; Hydrogen-Ion Concentration; Imidazoles; Norepinephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Tetrahydronaphthalenes; Yohimbine | 2000 |
Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using intracellular Ca(2+) changes: evidence for cross-talk between recombinant alpha(2A)- and native alpha(1)-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aniline Compounds; Animals; Azepines; Binding, Competitive; Brimonidine Tartrate; Calcium; Cell Line; Cricetinae; Dexmedetomidine; Dose-Response Relationship, Drug; Doxazosin; Estrenes; Fluorescence; Gene Expression; Humans; Imidazoles; Norepinephrine; Prazosin; Pyrrolidinones; Quinoxalines; Radioligand Assay; Receptor Cross-Talk; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Signal Transduction; Tetrahydronaphthalenes; Thapsigargin; Xanthenes; Yohimbine | 2000 |
Atipamezole, an imidazoline-type alpha(2)-adrenoceptor inhibitor, binds to human platelets and inhibits their adrenaline-induced aggregation more effectively than yohimbine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Binding Sites; Binding, Competitive; Blood Platelets; Dexmedetomidine; Drug Evaluation, Preclinical; Epinephrine; Humans; Imidazoles; Phenylephrine; Platelet Aggregation Inhibitors; Prazosin; Receptors, Adrenergic, alpha-2; Yohimbine | 2000 |
Effect of dexmedetomidine on the release of [3H]-noradrenaline from rat kidney cortex slices: characterization of alpha2-adrenoceptor.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Berberine; Chromatography, High Pressure Liquid; Dexmedetomidine; Dose-Response Relationship, Drug; Feedback; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Kidney Cortex; Male; Morphine; Norepinephrine; Piperazines; Prazosin; Prednisone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tritium | 2001 |
Noradrenergic modulation of serotonin release in rat dorsal and median raphé nuclei via alpha(1) and alpha(2A) adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Desipramine; Dexmedetomidine; Electric Stimulation; Electrophysiology; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Male; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Serotonin | 2001 |
Stress-mediated modulation of B(alpha)P-induced hepatic CYP1A1: role of catecholamines.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Benzo(a)pyrene; Catecholamines; Corticosterone; Cytochrome P-450 CYP1A1; Dexmedetomidine; Enzyme Induction; Imidazoles; Liver; Male; Prazosin; Propranolol; Rats; Rats, Wistar; Reserpine; Restraint, Physical; RNA, Messenger; Stress, Physiological | 2004 |
Alpha(1)-adrenergic and alpha(2)-adrenergic balance in the dorsal pons and gross behavioral activity of mice in a novel environment.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Behavior, Animal; Dexmedetomidine; Dose-Response Relationship, Drug; Environment; Imidazoles; Male; Mice; Motor Activity; Pons; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2 | 2005 |
Benzo(alpha)pyrene-induced up-regulation of CYP1A2 gene expression: role of adrenoceptor-linked signaling pathways.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Benzo(a)pyrene; Catecholamines; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Dexmedetomidine; Epinephrine; Gene Expression Regulation, Enzymologic; Guanethidine; Levodopa; Male; Oxidoreductases; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic; Reserpine; RNA, Messenger; Signal Transduction; Sympatholytics; Up-Regulation | 2006 |
Dexmedetomidine produces dual alpha2-adrenergic agonist and alpha1-adrenergic antagonist actions on human isolated internal mammary artery.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Coronary Artery Bypass; Dexmedetomidine; Female; Humans; Male; Mammary Arteries; Middle Aged; Phenylephrine; Potassium Chloride; Prazosin; Vasoconstriction; Yohimbine | 2007 |
Dexmedetomidine enhances the local anesthetic action of lidocaine via an alpha-2A adrenoceptor.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Lidocaine; Male; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha-2; Yohimbine | 2008 |
Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Aorta; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthalenes; NG-Nitroarginine Methyl Ester; Pertussis Toxin; Prazosin; Propionates; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Thromboxane | 2010 |
Perineural dexmedetomidine added to ropivacaine for sciatic nerve block in rats prolongs the duration of analgesia by blocking the hyperpolarization-activated cation current.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amides; Analgesia; Anesthetics, Local; Animals; Behavior, Animal; Colforsin; Cyclic Nucleotide-Gated Cation Channels; Dexmedetomidine; Dose-Response Relationship, Drug; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Hypnotics and Sedatives; Idazoxan; Male; Nerve Block; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Prazosin; Pyrimidines; Rats; Rats, Sprague-Dawley; Ropivacaine; Sciatic Nerve | 2011 |
Dual effects of α2 -adrenoceptors in modulating myogenic tone in sheep isolated internal anal sphincter.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Anal Canal; Animals; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Muscle Contraction; Prazosin; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Sheep; Tissue Culture Techniques | 2014 |
Brain interstitial fluid drainage and extracellular space affected by inhalational isoflurane: in comparison with intravenous sedative dexmedetomidine and pentobarbital sodium.
Topics: Administration, Inhalation; Administration, Intravenous; Anesthetics, Inhalation; Animals; Biological Transport; Brain; Caudate Nucleus; Dexmedetomidine; Drainage; Extracellular Fluid; Extracellular Space; Humans; Hypnotics and Sedatives; Imidazoles; Isoflurane; Male; Norepinephrine; Pentobarbital; Prazosin; Propranolol; Rats, Sprague-Dawley; Thalamus | 2020 |
Opposing functions of α- and β-adrenoceptors in the formation of processes by cultured astrocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Astrocytes; Cells, Cultured; Cyclic AMP; Dexmedetomidine; Imidazoles; Isoproterenol; Norepinephrine; Prazosin; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Signal Transduction | 2021 |
Dexmedetomidine-Induced Aortic Contraction Involves Transactivation of the Epidermal Growth Factor Receptor in Rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Aorta; Dexmedetomidine; ErbB Receptors; Muscle, Smooth, Vascular; Phosphorylation; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; src-Family Kinases; Transcriptional Activation; Tyrosine; Yohimbine | 2022 |