Page last updated: 2024-08-24

dexmedetomidine and morphine

dexmedetomidine has been researched along with morphine in 129 studies

Research

Studies (129)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (0.78)18.2507
2000's25 (19.38)29.6817
2010's74 (57.36)24.3611
2020's29 (22.48)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bradshaw, CJ; Brealey, D; Caudwell, E; Feneck, R; Grounds, RM; Naughton, C; Singer, M; Spencer, R; Treacher, D; Vedio, A; Venn, RM; Willatts, SM1
Asano, T; Dohi, S; Iida, H; Ohta, S; Shimonaka, H1
Asano, T; Dohi, S; Iida, H1
Benedek, G; Dobos, I; Horvath, G; Joó, G; Kekesi, G; Klimscha, W; Szikszay, M1
Adachi, YU; Satoh, T; Taoda, M; Uchihashi, Y; Vizi, ES; Watanabe, K1
Genähr, A; Grosse, J; Konertz, W; Kox, WJ; Moshirzadeh, M; Sidiropoulos, A; Spies, CD; Triltsch, AE; von Homeyer, P; Welte, M1
Clark, JD; Davies, MF; Haimor, F; Lighthall, G1
England, M; Herr, DL; Sum-Ping, ST1
Arain, SR; Ebert, TJ; Ruehlow, RM; Uhrich, TD1
Alhashemi, JA; Kaki, AM1
Asai, T; Inada, T; Shingu, K; Yamada, M1
Angus, JA; Tham, SM; Tudor, EM; Wright, CE1
Guler, T; Gunduz, M; Isik, G; Unlugenc, H; Yagmur, O1
Benedek, G; Dobos, I; Horvath, G; Kekesi, G; Klimscha, W1
Basagan-Mogol, E; Gurbet, A; Kaya, FN; Ozcan, B; Turker, G; Ugun, F1
Aoe, T; Kozikowski, A; Neale, JH; Saito, O; Sarva, J; Yamamoto, T1
Boyaci, A; Gulcu, N; Ugur, F1
Maze, M; Sanders, RD1
Davison, KJ; Higa, T; Kakinohana, M; Marsala, M; Nakamura, S; Oshiro, M; Saikawa, S; Sugahara, K1
Altemyatt, S; Bakhamees, HS; El-Halafawy, YM; El-Kerdawy, HM; Gouda, NM1
Gómez-Vázquez, ME; Hernández-Jiménez, A; Hernández-Salazar, E; Pérez-Sánchez, A; Salazar-Páramo, M; Zepeda-López, VA1
Gerancher, JC; Nagle, PC1
Christianson, CA; Hua, XY; Nazarian, A; Yaksh, TL1
Fan, SZ; Lin, CJ; Lin, FS; Lin, TF; Sun, WZ; Wang, YP; Yeh, YC1
Bass, F; Campbell, M; Chen, J; Grant, P; Hammond, N; Shehabi, Y; Wolfenden, H1
Bliesener, B; Kleinschmidt, S1
Diefenderfer, JW; Friedman, EM; Glover, CD; Larrier, DR; McGilberry, M; Olutoye, OA; Watcha, MF; Wyatt, MM1
Alkan, Z; Demirgan, S; Ozyuvacı, E; Sitilci, AT; Yiğit, O1
Hagihira, S; Hayashi, Y; Mashimo, T; Suzuki, T; Tamagaki, S1
Aantaa, R; Iirola, T; Neuvonen, PJ; Olkkola, KT; Scheinin, M; Vilo, S; Wendelin-Saarenhovi, M1
Allegaert, K; Thewissen, L1
Kasaba, T1
Abd Aziz, N; Awaisu, A; Chue, MC; Hassan, J; Hassan, Y; Kamarulzaman, MH; Yong, CY1
Wang, Q; Wang, X; Zhang, XF; Zhou, ZJ; Zhuang, PJ1
Altun, A; Bagcivan, I; Durmus, N; Gursoy, S; Ozdemir, E1
Chalkiadis, GA; Hallett, BR1
Blaudszun, G; Elia, N; Lysakowski, C; Tramèr, MR1
Gossett, JM; Gupta, P; Roth, SJ; Sabati, A; Tesoro, TM; Tobias, JD; Whiteside, W1
Abdel Azeem, MS; Khalil, MA1
Cao, JP; He, XY; Shi, XY; Zhang, H1
Devlin, JW; Manjourides, J; Papadopoulos, S; Torbic, H1
O, O; Smith, LJ1
Bednarski, RM; Ebner, LS; Hubbell, JA; Lerche, P1
Alatzas, DG; Kazakos, GM; Kostoulas, P; Kritsepi-Konstantinou, M; Mylonakis, ME; Polizopoulou, ZS1
Gasthuys, F; Gozalo-Marcilla, M; Hopster, K; Krajewski, AE; Schauvliege, S; Schwarz, A1
Moens, YP; Pavlidou, K; Raptopoulos, D; Savvas, I; Vasilakos, D1
Duchateau, L; Gasthuys, F; Gozalo-Marcilla, M; Schauvliege, S; Steblaj, B1
Beazley, SG; Benmansour, P; Bracamonte, JL; Duke-Novakovski, T; Husulak, ML; Withnall, E1
Gao, XZ; Jin, Y; Li, WY; Liu, HJ; Liu, XM; Xia, M1
Cotugno, RE; Hotz, J; Jones, JS; Nebar, S; Parke, EJ; Semenova, J; Shrader, MW; Singhal, NR; Soares, N1
Fauber, AE; Ko, JC; Lambrechts, NE; Moore, GE; Soto, N1
Bainbridge, D; Jolly, SS; Lavi, R; Lavi, S; Manji, F; Randhawa, V1
Cheung, CW; Choi, SW; Irwin, MG; Law, WL; Qiu, Q; Ying, AC1
Cardoso, CG; da Silva, TH; de Mattos-Junior, E; Marques, DR1
Gao, T; Ji, Q; Li, L; Liu, K; Song, J; Sun, Q1
Ge, DJ; Li, JY; Qi, B; Tang, G3
Boesch, JM; Campoy, L; Gleed, RD; Kirch, PJ; Learn, MM; Martin-Flores, M; Mastrocco, A; Sakai, DM1
Abeeleh, MA; Absalom, AR; Abu-Halaweh, S; AlOweidi, A; Mason, KP; Obeidat, F; Qudaisat, I; Robinson, F1
Kalra, B; Kaur, N; Mohta, M; Sethi, AK1
Cui, XG; Guo, YP; Lu, ZF; Lv, XQ; Zeng, XZ1
Chan, IA; Gorman, KJ; Maslany, JG; McKay, WP; O'Brien, JM1
Auckburally, A; Borges, LP; Carvalho, LL; Cerejo, SA; Mattos-Junior, E; Nishimura, LT1
Abdel-Ghaffar, HS; Fares, KM; Mohamed, SA1
Ge, DJ; Li, JY; Li, YY; Qi, B1
Boesch, JM; Campoy, L; Gleed, RD; Learn, MM; Martin-Flores, M; Mastrocco, A; Sakai, DM1
Cao, WZ; Xu, SA; Xu, XQ; Yu, HJ1
Geng, ZY; Li, BY; Wang, DX1
Chen, D; Huang, X; Li, G; Li, Y; Qi, X; Wang, X1
El-Rahman, AM; Fares, KM; Mohamed, SA1
Ge, DJ; Kong, M; Qi, B; Zhao, JN1
Boesch, JM; Campoy, L; Kirch, P; Learn, MM; Lorenzutti, AM; Martin-Flores, M; Mastrocco, A; Stone, M1
Dutta, V; Jayant, A; Kumar, B; Mishra, AK1
Brudney, CS; Ehieli, E; Pyati, S; Yalamuri, S1
Borle, A; Goudra, B; Mulier, JP; Panwar, R; Singh, PM; Sinha, A1
Martin, C; Nadler, E; Nelson, J; Quezado, ZM; Vaughns, JD1
Barbosa, VF; de Araujo, NLLC; Dórea Neto, FA; Martins Filho, EF; Oriá, AP; Otero, AR; Schäffer, DPH1
Abd El-Rahman, AM; El Sherif, FA; Mohamed, SA; Sayed, DM1
Brioschi, FA; Carotenuto, AM; Gioeni, D; Jacchetti, A1
Blackwell, SJ; Linton, JL; Lopez, MM; Zech, D1
Auckburally, A; de Mattos-Junior, E; Garcia, DO; Honsho, CS; Nishimura, LT; Santilli, J; Vieira, BHB1
Benegni, S; Cogo, P; Garisto, C; Pezzella, C; Ricci, Z; Tofani, L1
Ball, NM; Evans, MC; Frame, SC; Haney, AL; Hochstetler, JL; Little, AK; Mack, EH; O'Donnell, JL; Rickett, BM; Thompson, AJ1
Babych, V; Bielka, K; Inozemtsev, O; Kuchyn, I; Martycshenko, K1
Cui, X; Ding, W; Wan, Q; Zeng, X1
Chen, Y; Ding, W; Li, D; Liu, H; Wang, H; Wang, L; Zeng, X1
Hu, J; Li, CJ; Li, HJ; Mu, DL; Wang, DX; Wei, XN1
Joynt, GM; Lee, A; Ling, L; Tse, AHW1
Brykczyński, M; Ely, EW; Kotfis, K; Safranow, K; Strzelbicka, M; Zegan-Barańska, M; Żukowski, M1
Dagenais, M; Di Genova, T; Fontela, P; Kongkiattikul, L; Ruo, N; Zavalkoff, S1
Franci, P; Rabozzi, R; Sarotti, D1
Breatnach, CV; Cousins, G; Dawkins, I; Doherty, DR; Gallagher, PJ; Hayden, JC; Healy, M; Leacy, FP1
Dong, BH; Li, J; Yang, JS; Ye, JM1
Chambers, P; Karna, SR; Kongara, K; Lopez-Villalobos, N; Singh, PM1
Alami, RS; Aouad, MT; Daou, D; Jabbour-Khoury, S; Naji, S; Safadi, BY; Siddik-Sayyid, SM; Zeeni, C1
Bosson, JL; Bouzat, P; Deletombe, B; Falcon, D; Giorgis-Allemand, L; Godon, A; Payen, JF; Trouve-Buisson, T1
Donato, J; Lewis, T; Rao, K1
Chambers, P; Karna, SR; Kongara, K; Singh, P1
El-Dib, M; Inder, TE; Massaro, AN; McPherson, C; Miller, SP1
Geng, ZY; Li, HJ; Li, XY; Liu, S1
Hatachi, T; Inata, Y; Kyogoku, M; Sofue, T; Takeuchi, M1
Li, Y; Lin, L; Liu, Y; Luo, Y; Yang, P; Zhang, H1
Chambers, P; Johnson, CB; Karna, SR; Kongara, K; Lopez-Villalobos, N; Singh, P; Stewart, LA1
Doi, M; Irifune, M; Kanematsu, T; Morioka, N; Mukai, A; Nakata, Y; Ogawa, Y; Oue, K; Sakai, N; Shimizu, Y; Yoshida, M1
Aksu, R; Altuntaş, R; Bayram, A; Güler, G; Güney, A; Ülgey, A1
Angert, RM; Cosnahan, AS; Jano, E; Wachtel, EV1
Duke-Novakovski, T; Fujiyama, M; Jones, T1
Authier, S; Boulay, E; Downey, AM; Guerrier, M; Maghezzi, S; Pugsley, M; Smutova, V; St-Pierre, J; Troncy, E1
Hansen, A; Labrecque, M; Leeman, K; Moline, M; Morton, SU1
Bailey, KM; Bini, G; Chiavaccini, L; Cohen, EB; Messenger, KM1
Fu, Q; He, Y; Hu, T; Huang, L; Li, X; Tong, X; Zhang, Y; Zhou, Y1
Dietz, R; Ross, E; Welter, KJ1
Abrard, S; Berlier, J; Bouffard, Y; Carabalona, JF; Cerro, V; Le-Goff, MC; Rimmelé, T; Subtil, F; Tête, H1
Abraham, JT; Falola, RA; Lombana, NF; Roth, C; Saint-Cyr, MH; Zolfaghari, K1
Eldeek, AM; Hefni, AF; Ismael, SA; Shaban, AR1
Bhatia, A; Chan, V; Chin, KJ; Gandhi, R; Jack, JM; Jin, R; Muñoz-Leyva, F; Perlas, A1
Altun, D; Arnaz, A; Doğan, A; Oktay, A; Sarıoğlu, T; Türköz, R; Yalçinbaş, Y; Yüksek, A1
Bagntasarian, S; Christidis, P; Koraki, E; Mantzoros, I; Sifaki, F; Theodoraki, K1
Abdelemam, RM; Elmasry, HM; Fares, KM; Kamal, SM; Mansour, S; Mohamed, SA1
Miskimins, R; Mitchell, J; Sarangarm, P; Wiemann, B1
Albrecht, E; Cabaton, J; Capel, D; De Paulis, D; Godenèche, A; Rossel, JB; Wolmarans, MR1
Comer, SD; De Vivo, M; Jones, JD; Levin, FR; Rajachandran, L; Risinger, R; Sabados, J; Yocca, F1
Abdelghaffar, RA; Algyar, MF; Fargaly, OS; Hamed, MA; Moussa, MA1
Eisenbraun, A; Martin, E; Schaff, HV; Schroeder, D; Wittwer, ED1
Ali, BEEH; El-Shaer, AN; Elderh, MSH; Khaja, MAR; Khalil, BNM; Taeimah, MOA1
Bridges, J; Chagas, J; Chambers, JP; Ishikawa, Y; Kurihara, M; Sano, H; Short, E1

Reviews

11 review(s) available for dexmedetomidine and morphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Analgosedation in neonates: do we still need additional tools after 30 years of clinical research?
    Archives of disease in childhood. Education and practice edition, 2011, Volume: 96, Issue:3

    Topics: Acetaminophen; Adrenergic alpha-2 Receptor Agonists; Analgesia; Analgesics, Opioid; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant, Newborn; Midazolam; Morphine; Pain; Pain Measurement; Piperidines; Propofol; Quality of Health Care; Remifentanil

2011
[Some adjuvants added to local anesthetics improve the duration and quality of epidural anesthesia].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59 Suppl

    Topics: Adjuvants, Anesthesia; Amines; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Dexmedetomidine; Droperidol; Drug Compounding; Epinephrine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Magnesium Sulfate; Midazolam; Morphine; Neostigmine

2010
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
    Anesthesiology, 2012, Volume: 116, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dexmedetomidine; Hemodynamics; Humans; Hyperalgesia; Hypotension; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Randomized Controlled Trials as Topic

2012
Dexmedetomidine versus morphine or fentanyl in the management of children after tonsillectomy and adenoidectomy: a meta-analysis of randomized controlled trials.
    The Annals of otology, rhinology, and laryngology, 2013, Volume: 122, Issue:2

    Topics: Adenoidectomy; Analgesics, Non-Narcotic; Analgesics, Opioid; Dexmedetomidine; Fentanyl; Humans; Morphine; Pain, Postoperative; Randomized Controlled Trials as Topic; Tonsillectomy

2013
Analgesia in the surgical intensive care unit.
    Postgraduate medical journal, 2017, Volume: 93, Issue:1095

    Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; Clonidine; Critical Care; Cyclohexanecarboxylic Acids; Dexmedetomidine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydromorphone; Intensive Care Units; Ketamine; Lidocaine; Morphine; Pain; Pain Management; Pain Measurement; Pain, Postoperative; Physical Therapy Modalities

2017
Perioperative analgesic profile of dexmedetomidine infusions in morbidly obese undergoing bariatric surgery: a meta-analysis and trial sequential analysis.
    Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2017, Volume: 13, Issue:8

    Topics: Analgesics, Non-Narcotic; Dexmedetomidine; Humans; Infusions, Intravenous; Length of Stay; Morphine; Obesity, Morbid; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Randomized Controlled Trials as Topic

2017
Altered Pharmacokinetics in Prolonged Infusions of Sedatives and Analgesics Among Adult Critically Ill Patients: A Systematic Review.
    Clinical therapeutics, 2018, Volume: 40, Issue:9

    Topics: Adult; Analgesics; Critical Illness; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lorazepam; Midazolam; Morphine; Propofol; Remifentanil; Sufentanil; Time Factors

2018
Pharmacology of Common Analgesic and Sedative Drugs Used in the Neonatal Intensive Care Unit.
    Clinics in perinatology, 2019, Volume: 46, Issue:4

    Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Combined Modality Therapy; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Neonatal; Midazolam; Morphine; Pain; Pain Management; Pharmacogenomic Variants; Precision Medicine; Remifentanil

2019
The influence of pain, agitation, and their management on the immature brain.
    Pediatric research, 2020, Volume: 88, Issue:2

    Topics: Algorithms; Analgesics, Opioid; Brain; Chronic Pain; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Morphine; Neuroimaging; Pain; Pain Management; Remifentanil; Respiration, Artificial; Stress, Psychological; Sucrose

2020
Dexmedetomidine reduces postoperative pain and speeds recovery after bariatric surgery: a meta-analysis of randomized controlled trials.
    Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2022, Volume: 18, Issue:6

    Topics: Analgesics, Opioid; Bariatric Surgery; Dexmedetomidine; Humans; Morphine; Pain, Postoperative; Postoperative Nausea and Vomiting; Randomized Controlled Trials as Topic

2022

Trials

69 trial(s) available for dexmedetomidine and morphine

ArticleYear
Preliminary UK experience of dexmedetomidine, a novel agent for postoperative sedation in the intensive care unit.
    Anaesthesia, 1999, Volume: 54, Issue:12

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Cardiovascular Diseases; Conscious Sedation; Critical Care; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Morphine; Postoperative Care

1999
Bispectral index-guided sedation with dexmedetomidine in intensive care: a prospective, randomized, double blind, placebo-controlled phase II study.
    Critical care medicine, 2002, Volume: 30, Issue:5

    Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Critical Care; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Morphine; Propofol; Prospective Studies

2002
ICU sedation after coronary artery bypass graft surgery: dexmedetomidine-based versus propofol-based sedation regimens.
    Journal of cardiothoracic and vascular anesthesia, 2003, Volume: 17, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Analgesics, Opioid; Anti-Arrhythmia Agents; Biomarkers; Blood Pressure; Blood Urea Nitrogen; Canada; Conscious Sedation; Coronary Artery Bypass; Coronary Artery Disease; Dexmedetomidine; Diuretics; Female; gamma-Glutamyltransferase; Heart Rate; Humans; Hypnotics and Sedatives; Incidence; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Morphine; Postoperative Care; Postoperative Complications; Propofol; Respiration, Artificial; Systole; Time Factors; Treatment Outcome; United States; Vasodilator Agents

2003
The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:1

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Blood Pressure; Dexmedetomidine; Double-Blind Method; Female; Heart Rate; Humans; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Respiratory Mechanics

2004
Dexmedetomidine in combination with morphine PCA provides superior analgesia for shockwave lithotripsy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:4

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Intravenous; Dexmedetomidine; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Lithotripsy; Male; Midazolam; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Psychomotor Performance; Time Factors; Tramadol

2004
The effect of pre-anaesthetic administration of intravenous dexmedetomidine on postoperative pain in patients receiving patient-controlled morphine.
    European journal of anaesthesiology, 2005, Volume: 22, Issue:5

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Dexmedetomidine; Double-Blind Method; Female; Hemodynamics; Humans; Injections, Intravenous; Intubation, Intratracheal; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Complications; Preanesthetic Medication; Prospective Studies; Time Factors

2005
Intraoperative infusion of dexmedetomidine reduces perioperative analgesic requirements.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:7

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Dexmedetomidine; Double-Blind Method; Female; Humans; Infusions, Intravenous; Intraoperative Care; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies; Time Factors

2006
Effects of dexmedetomidine in morbidly obese patients undergoing laparoscopic gastric bypass.
    Middle East journal of anaesthesiology, 2007, Volume: 19, Issue:3

    Topics: Adrenergic alpha-Agonists; Aged; Analgesics, Opioid; Anastomosis, Roux-en-Y; Anesthesia, Intravenous; Anesthetics; Anesthetics, Intravenous; Blood Pressure; Body Mass Index; Dexmedetomidine; Female; Gastric Bypass; Heart Rate; Humans; Laparoscopy; Male; Middle Aged; Monitoring, Intraoperative; Morphine; Obesity, Morbid; Pain, Postoperative; Preanesthetic Medication; Propofol

2007
Clinical analgesic efficacy and side effects of dexmedetomidine in the early postoperative period after arthroscopic knee surgery.
    Journal of clinical anesthesia, 2007, Volume: 19, Issue:8

    Topics: Acetaminophen; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Blood Pressure; Bradycardia; Dexmedetomidine; Double-Blind Method; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Knee Joint; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Period; Prospective Studies; Time Factors; Treatment Outcome

2007
Effect of combining dexmedetomidine and morphine for intravenous patient-controlled analgesia.
    British journal of anaesthesia, 2009, Volume: 102, Issue:1

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Blood Pressure; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Heart Rate; Humans; Hysterectomy; Infusions, Intravenous; Middle Aged; Morphine; Pain, Postoperative; Postoperative Nausea and Vomiting

2009
Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: a randomized controlled trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study).
    Anesthesiology, 2009, Volume: 111, Issue:5

    Topics: Adrenergic alpha-Agonists; Aged; Analgesics, Opioid; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Intra-Aortic Balloon Pumping; Male; Morphine; Pain, Postoperative; Postoperative Care; Propofol

2009
The effect of intraoperative dexmedetomidine on postoperative analgesia and sedation in pediatric patients undergoing tonsillectomy and adenoidectomy.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:2

    Topics: Adenoidectomy; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Child; Child, Preschool; Consciousness; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Intraoperative Care; Kaplan-Meier Estimate; Male; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies; Recovery Room; Time Factors; Tonsillectomy; Treatment Outcome

2010
[The effect of perioperative infused dexmedetomidine on postoperative analgesic consumption in mastoidectomy operations].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2010, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Dexmedetomidine; Humans; Infusions, Intravenous; Mastoid; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Tramadol

2010
Dexmedetomidine inhibits gastric emptying and oro-caecal transit in healthy volunteers.
    British journal of anaesthesia, 2011, Volume: 106, Issue:4

    Topics: Acetaminophen; Adrenergic alpha-2 Receptor Agonists; Adult; Analgesics, Opioid; Breath Tests; Dexmedetomidine; Gastric Emptying; Gastrointestinal Transit; Humans; Hypnotics and Sedatives; Male; Morphine; Young Adult

2011
Efficacy and safety of dexmedetomidine versus morphine in post-operative cardiac surgery patients.
    International journal of clinical pharmacy, 2011, Volume: 33, Issue:2

    Topics: Aged; Blood Pressure; Cardiac Surgical Procedures; Dexmedetomidine; Female; Heart Rate; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Malaysia; Male; Middle Aged; Morphine; Narcotics; Pain Measurement; Pain, Postoperative; Pilot Projects; Sleep; Time Factors; Treatment Outcome

2011
Postoperative respiratory and analgesic effects of dexmedetomidine or morphine for adenotonsillectomy in children with obstructive sleep apnoea.
    Anaesthesia, 2011, Volume: 66, Issue:11

    Topics: Adenoidectomy; Adolescent; Analgesics; Child; Child, Preschool; Dexmedetomidine; Double-Blind Method; Female; Humans; Male; Morphine; Respiration; Sleep Apnea, Obstructive; Tonsillectomy

2011
A comparison of epidural analgesia provided by bupivacaine alone, bupivacaine + morphine, or bupivacaine + dexmedetomidine for pelvic orthopedic surgery in dogs.
    Veterinary anaesthesia and analgesia, 2013, Volume: 40, Issue:5

    Topics: Analgesia, Epidural; Animals; Bupivacaine; Dexmedetomidine; Dogs; Double-Blind Method; Hindlimb; Morphine

2013
Effect of dexmedetomidine, morphine-lidocaine-ketamine, and dexmedetomidine-morphine-lidocaine-ketamine constant rate infusions on the minimum alveolar concentration of isoflurane and bispectral index in dogs.
    American journal of veterinary research, 2013, Volume: 74, Issue:7

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Local; Animals; Consciousness Monitors; Cross-Over Studies; Dexmedetomidine; Dogs; Drug Interactions; Drug Therapy, Combination; Female; Isoflurane; Ketamine; Lidocaine; Male; Morphine; Pulmonary Alveoli

2013
Comparison of the influence of two different constant-rate infusions (dexmedetomidine versus morphine) on anaesthetic requirements, cardiopulmonary function and recovery quality in isoflurane anaesthetized horses.
    Research in veterinary science, 2013, Volume: 95, Issue:3

    Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Dexmedetomidine; Heart; Horses; Hypnotics and Sedatives; Isoflurane; Ketamine; Lung; Morphine; Narcotics

2013
Cardiopulmonary effects of an infusion of remifentanil or morphine in horses anesthetized with isoflurane and dexmedetomidine.
    Veterinary anaesthesia and analgesia, 2014, Volume: 41, Issue:4

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Cross-Over Studies; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Rate; Horses; Isoflurane; Male; Morphine; Piperidines; Remifentanil

2014
Effect of intrathecal dexmedetomidine on spinal morphine analgesia in patients with refractory cancer pain.
    Journal of palliative medicine, 2014, Volume: 17, Issue:7

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Cross-Over Studies; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Spinal; Male; Middle Aged; Morphine; Neoplasms; Outcome Assessment, Health Care; Pain Management; Pain Measurement; Pain, Intractable

2014
Analgesic effect of intra-articularly administered morphine, dexmedetomidine, or a morphine-dexmedetomidine combination immediately following stifle joint surgery in dogs.
    Journal of the American Veterinary Medical Association, 2014, Jun-01, Volume: 244, Issue:11

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anterior Cruciate Ligament; Dexmedetomidine; Dog Diseases; Dogs; Drug Therapy, Combination; Injections, Intra-Articular; Morphine; Pain, Postoperative; Rupture; Stifle

2014
The effects of intra-operative dexmedetomidine on postoperative pain, side-effects and recovery in colorectal surgery.
    Anaesthesia, 2014, Volume: 69, Issue:11

    Topics: Aged; Analgesics, Non-Narcotic; Colon; Dexmedetomidine; Double-Blind Method; Female; Humans; Intraoperative Period; Laparoscopy; Male; Middle Aged; Morphine; Pain, Postoperative; Rectum

2014
Cardiorespiratory, sedative and antinociceptive effects of dexmedetomidine alone or in combination with methadone, morphine or tramadol in dogs.
    Veterinary anaesthesia and analgesia, 2014, Volume: 41, Issue:6

    Topics: Analgesia; Analgesics; Animals; Blood Pressure; Body Temperature; Cross-Over Studies; Deep Sedation; Dexmedetomidine; Dogs; Drug Therapy, Combination; Female; Heart; Heart Rate; Male; Methadone; Morphine; Respiratory Physiological Phenomena; Respiratory Rate; Tramadol

2014
The Opioid-sparing Effect of Intraoperative Dexmedetomidine Infusion After Craniotomy.
    Journal of neurosurgical anesthesiology, 2016, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Craniotomy; Dexmedetomidine; Female; Humans; Infusions, Intravenous; Intraoperative Care; Male; Middle Aged; Morphine; Pain, Postoperative; Young Adult

2016
Intraoperative Dexmedetomidine Promotes Postoperative Analgesia in Patients After Abdominal Colectomy: A Consort-Prospective, Randomized, Controlled Clinical Trial.
    Medicine, 2015, Volume: 94, Issue:37

    Topics: Analgesia, Patient-Controlled; Analgesics; Anesthesia; Colectomy; Dexmedetomidine; Female; Humans; Male; Middle Aged; Morphine; Pain, Postoperative; Prospective Studies

2015
Intraoperative Dexmedetomidine Promotes Postoperative Analgesia and Recovery in Patients after Abdominal Colectomy: A CONSORT-Prospective, Randomized, Controlled Clinical Trial.
    Medicine, 2015, Volume: 94, Issue:43

    Topics: Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Colectomy; Dexmedetomidine; Fatigue; Female; Humans; Intraoperative Care; Male; Middle Aged; Morphine; Pain, Postoperative; Prospective Studies

2015
Evaluation of oral maropitant as an antiemetic in cats receiving morphine and dexmedetomidine.
    Journal of feline medicine and surgery, 2016, Volume: 18, Issue:11

    Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Antiemetics; Cats; Dexmedetomidine; Female; Hysterectomy; Morphine; Ovariectomy; Prospective Studies; Quinuclidines; Treatment Outcome; Vomiting

2016
Dexmedetomidine versus morphine infusion following laparoscopic bariatric surgery: effect on supplemental narcotic requirement during the first 24 h.
    Surgical endoscopy, 2016, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Bariatric Surgery; Dexmedetomidine; Female; Humans; Infusions, Intravenous; Laparoscopy; Male; Middle Aged; Morphine; Pain, Postoperative; Pilot Projects; Visual Analog Scale; Young Adult

2016
Efficacy of dexmedetomidine as an adjuvant in paravertebral block in breast cancer surgery.
    Journal of anesthesia, 2016, Volume: 30, Issue:2

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; Breast Neoplasms; Bupivacaine; Dexmedetomidine; Double-Blind Method; Female; Fentanyl; Humans; Mastectomy; Mastectomy, Modified Radical; Middle Aged; Morphine; Nerve Block; Pain, Postoperative; Postoperative Nausea and Vomiting; Prospective Studies

2016
Epidural Co-Administration of Dexmedetomidine and Levobupivacaine Improves the Gastrointestinal Motility Function after Colonic Resection in Comparison to Co-Administration of Morphine and Levobupivacaine.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Aged; Analgesia, Epidural; Bupivacaine; Colon; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Feces; Female; Flatulence; Gastrointestinal Motility; Humans; Levobupivacaine; Male; Middle Aged; Morphine; Pain Management; Pain, Postoperative; Prospective Studies; Time Factors; Treatment Outcome

2016
Dexmedetomidine during total knee arthroplasty performed under spinal anesthesia decreases opioid use: a randomized-controlled trial.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2016, Volume: 63, Issue:5

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Replacement, Knee; Dexmedetomidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; Pain, Postoperative

2016
Behavioral and cardiopulmonary effects of dexmedetomidine alone and in combination with butorphanol, methadone, morphine or tramadol in conscious sheep.
    Veterinary anaesthesia and analgesia, 2016, Volume: 43, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Animals; Butorphanol; Deep Sedation; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; Male; Methadone; Morphine; Respiratory Rate; Sheep; Tramadol

2016
Intraoperative Dexmedetomidine Promotes Postoperative Analgesia and Recovery in Patients after Abdominal Hysterectomy: a Double-Blind, Randomized Clinical Trial.
    Scientific reports, 2016, Feb-23, Volume: 6

    Topics: Analgesia, Patient-Controlled; Anesthesia, General; Anesthetics, Intravenous; Dexmedetomidine; Double-Blind Method; Fatigue; Female; Humans; Hysterectomy; Intraoperative Care; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Piperidines; Propofol; Remifentanil; Surveys and Questionnaires

2016
Combined Intrathecal Morphine and Dexmedetomidine for Postoperative Analgesia in Patients Undergoing Major Abdominal Cancer Surgery.
    Pain medicine (Malden, Mass.), 2016, Volume: 17, Issue:11

    Topics: Adult; Analgesics, Opioid; Blood Pressure; Bupivacaine; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Rate; Humans; Injections, Spinal; Male; Middle Aged; Morphine; Pain, Postoperative; Stomach Neoplasms

2016
Sex Differences in the Morphine-Sparing Effects of Intraoperative Dexmedetomidine in Patient-Controlled Analgesia Following General Anesthesia: A Consort-Prospective, Randomized, Controlled Clinical Trial.
    Medicine, 2016, Volume: 95, Issue:18

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, Intravenous; Dexmedetomidine; Female; Humans; Intraoperative Care; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Piperidines; Propofol; Remifentanil; Sex Factors

2016
Effects of maropitant in cats receiving dexmedetomidine and morphine.
    Journal of the American Veterinary Medical Association, 2016, Jun-01, Volume: 248, Issue:11

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Antiemetics; Cat Diseases; Cats; Dexmedetomidine; Drug Interactions; Female; Injections, Intramuscular; Injections, Subcutaneous; Morphine; Nausea; Quinuclidines; Single-Blind Method; Visual Analog Scale; Vomiting

2016
[Analgesic and Sedative Effect of Acupuncture Combined with Medicine on Patients Undergiong Cardiac Surgery].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2016, Volume: 36, Issue:3

    Topics: Acupuncture Analgesia; Analgesia; Analgesics; Cardiac Surgical Procedures; Dexmedetomidine; Electroacupuncture; Heart Rate; Humans; Hypnotics and Sedatives; Morphine; Pain; Pain Management; Respiration, Artificial

2016
[Effect of dexmedetomidine infusion on postoperative recovery for patients undergoing major spinal surgery during propofol anesthesia].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2016, Jun-18, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Aged; Analgesia; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intravenous; Dexmedetomidine; Heart Rate; Humans; Middle Aged; Morphine; Neurosurgical Procedures; Propofol; Sufentanil; Vomiting; Young Adult

2016
Comparison of Intrathecal Dexmedetomidine with Morphine as Adjuvants in Cesarean Sections.
    Biological & pharmaceutical bulletin, 2016, Sep-01, Volume: 39, Issue:9

    Topics: Adjuvants, Pharmaceutic; Adult; Analgesics; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Injections, Spinal; Morphine; Pain; Pregnancy; Pruritus; Shivering

2016
Intrathecal Dexmedetomidine, Ketamine, and their Combination Added to Bupivacaine for Postoperative Analgesia in Major Abdominal Cancer Surgery.
    Pain physician, 2016, Volume: 19, Issue:6

    Topics: Abdominal Neoplasms; Adult; Analgesia; Anesthetics, Local; Bupivacaine; Dexmedetomidine; Double-Blind Method; Female; Humans; Ketamine; Male; Middle Aged; Morphine; Pain, Postoperative

2016
Comparison of the morphine-sparing effect of intraoperative dexmedetomidine with and without loading dose following general anesthesia in multiple-fracture patients: A prospective, randomized, controlled clinical trial.
    Medicine, 2016, Volume: 95, Issue:33

    Topics: Adult; Analgesics, Non-Narcotic; Anesthesia, General; Anesthetics, Combined; Dexmedetomidine; Female; Fracture Fixation, Internal; Fractures, Multiple; Humans; Intraoperative Period; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Period; Prospective Studies

2016
Maropitant administered orally 2-2.5 h prior to morphine and dexmedetomidine reduces the incidence of emesis in cats.
    Journal of feline medicine and surgery, 2017, Volume: 19, Issue:8

    Topics: Administration, Oral; Analgesics, Opioid; Animals; Antiemetics; Cat Diseases; Cats; Dexmedetomidine; Female; Injections, Intramuscular; Morphine; Ovariectomy; Postoperative Nausea and Vomiting; Quinuclidines; Treatment Outcome

2017
Effect of Continuous Paravertebral Dexmedetomidine Administration on Intraoperative Anesthetic Drug Requirement and Post-Thoracotomy Pain Syndrome After Thoracotomy: A Randomized Controlled Trial.
    Journal of cardiothoracic and vascular anesthesia, 2017, Volume: 31, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Aged; Amides; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Humans; Intraoperative Care; Middle Aged; Morphine; Nerve Block; Pain Measurement; Pain, Postoperative; Propofol; Ropivacaine; Syndrome; Thoracotomy; Young Adult

2017
Effect of local wound infiltration with ketamine versus dexmedetomidine on postoperative pain and stress after abdominal hysterectomy, a randomized trial.
    European journal of pain (London, England), 2018, Volume: 22, Issue:5

    Topics: Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Dexmedetomidine; Double-Blind Method; Female; Humans; Hysterectomy; Ketamine; Middle Aged; Morphine; Pain, Postoperative; Treatment Outcome

2018
Effect of metoclopramide on nausea and emesis in dogs premedicated with morphine and dexmedetomidine.
    Veterinary anaesthesia and analgesia, 2018, Volume: 45, Issue:2

    Topics: Analgesics, Opioid; Animals; Antiemetics; Dexmedetomidine; Dogs; Dopamine Antagonists; Female; Male; Metoclopramide; Morphine; Nausea; Premedication; Single-Blind Method; Vomiting

2018
Use of low-dose dexmedetomidine in combination with opioids and midazolam in pediatric cardiac surgical patients: randomized controlled trial.
    Minerva anestesiologica, 2018, Volume: 84, Issue:9

    Topics: Analgesics, Opioid; Cardiac Surgical Procedures; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Infant; Male; Midazolam; Morphine

2018
Dexmedetomidine infusion as an analgesic adjuvant during laparoscopic сholecystectomy: a randomized controlled study.
    BMC anesthesiology, 2018, 04-20, Volume: 18, Issue:1

    Topics: Adjuvants, Anesthesia; Aged; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Dexmedetomidine; Drug Therapy, Combination; Female; Fentanyl; Humans; Infusions, Intravenous; Length of Stay; Male; Middle Aged; Morphine; Pain, Postoperative; Treatment Outcome

2018
CONSORT-epidural dexmedetomidine improves gastrointestinal motility after laparoscopic colonic resection compared with morphine.
    Medicine, 2018, Volume: 97, Issue:25

    Topics: Aged; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Colon; Dexmedetomidine; Female; Gastrointestinal Motility; Humans; Laparoscopy; Levobupivacaine; Male; Middle Aged; Morphine; Pain Management; Pain, Postoperative

2018
Investigation of single-dose thoracic paravertebral analgesia for postoperative pain control after thoracoscopic lobectomy - A randomized controlled trial.
    International journal of surgery (London, England), 2018, Volume: 57

    Topics: Aged; Amides; Analgesics; Anesthesia, Epidural; Dexmedetomidine; Female; Humans; Intraoperative Care; Male; Middle Aged; Morphine; Nerve Block; Pain Management; Pain, Postoperative; Pneumonectomy; Postoperative Period; Prospective Studies; Ropivacaine; Thoracoscopy; Treatment Outcome

2018
Dexmedetomidine in combination with morphine improves postoperative analgesia and sleep quality in elderly patients after open abdominal surgery: A pilot randomized control trial.
    PloS one, 2018, Volume: 13, Issue:8

    Topics: Aged; Comorbidity; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morphine; Odds Ratio; Pain, Postoperative; Pilot Projects; Sleep; Treatment Outcome

2018
Effects of intravenous dexmedetomidine infusion on local anaesthetic block: A spinal anaesthesia clinical model in dogs undergoing hind limb surgery.
    Research in veterinary science, 2019, Volume: 124

    Topics: Analgesics, Non-Narcotic; Anesthesia, Spinal; Animals; Bupivacaine; Dexmedetomidine; Dogs; Hindlimb; Infusions, Intravenous; Models, Animal; Morphine; Nerve Block; Prospective Studies; Random Allocation

2019
The Effect of Dexmedetomidine Added to Preemptive Ropivacaine Infiltration on Postoperative Pain After Lumbar Fusion Surgery: A Randomized Controlled Trial.
    Spine, 2019, Oct-01, Volume: 44, Issue:19

    Topics: Anesthetics, Local; Dexmedetomidine; Humans; Lumbar Vertebrae; Morphine; Pain, Postoperative; Ropivacaine; Spinal Fusion

2019
The Effect of Intraoperative Dexmedetomidine Versus Morphine on Postoperative Morphine Requirements After Laparoscopic Bariatric Surgery.
    Obesity surgery, 2019, Volume: 29, Issue:12

    Topics: Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Bariatric Surgery; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Intraoperative Care; Laparoscopy; Lebanon; Male; Middle Aged; Morphine; Obesity, Morbid; Pain, Postoperative; Young Adult

2019
Dexmedetomidine to facilitate non-invasive ventilation after blunt chest trauma: A randomised, double-blind, crossover, placebo-controlled pilot study.
    Anaesthesia, critical care & pain medicine, 2019, Volume: 38, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Analgesics, Opioid; Cross-Over Studies; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Injury Severity Score; Male; Middle Aged; Morphine; Noninvasive Ventilation; Pilot Projects; Placebos; Prospective Studies; Psychomotor Agitation; Thoracic Injuries; Time Factors; Wounds, Nonpenetrating

2019
Pharmacokinetics of morphine in combination with dexmedetomidine and maropitant following intramuscular injection in dogs anaesthetized with halothane.
    Journal of veterinary pharmacology and therapeutics, 2020, Volume: 43, Issue:2

    Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Antiemetics; Area Under Curve; Cross-Over Studies; Dexmedetomidine; Dogs; Drug Therapy, Combination; Half-Life; Halothane; Hypnotics and Sedatives; Injections, Intramuscular; Morphine; Quinuclidines

2020
Adding dexmedetomidine to morphine-based analgesia reduces early postoperative nausea in patients undergoing gynecological laparoscopic surgery: a randomized controlled trial.
    BMC anesthesiology, 2020, 01-08, Volume: 20, Issue:1

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Dexmedetomidine; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; Laparoscopy; Middle Aged; Morphine; Pain Management; Pain, Postoperative; Postoperative Nausea and Vomiting; Prospective Studies; Treatment Outcome

2020
The efficacy of transversus abdominis plane block with or without dexmedetomidine for postoperative analgesia in renal transplantation. A randomized controlled trial.
    International journal of surgery (London, England), 2020, Volume: 79

    Topics: Abdominal Muscles; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Dexmedetomidine; Double-Blind Method; Female; Humans; Kidney Transplantation; Male; Middle Aged; Morphine; Nerve Block; Pain, Postoperative; Prospective Studies

2020
Effect of combinations of morphine, dexmedetomidine and maropitant on the electroencephalogram in response to acute electrical stimulation in anaesthetized dogs.
    Journal of veterinary pharmacology and therapeutics, 2020, Volume: 43, Issue:6

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Animals; Antiemetics; Cross-Over Studies; Dexmedetomidine; Dogs; Electric Stimulation; Electroencephalography; Morphine; Quinuclidines

2020
Intravenous dexmedetomidine, morphine, or a combination can result in gallbladder wall thickening; with no significant association with plasma histamine concentrations.
    Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association, 2022, Volume: 63, Issue:3

    Topics: Animals; Dexmedetomidine; Dogs; Gallbladder; Histamine; Morphine; Pilot Projects; Prospective Studies

2022
Comparing Effect of Adding Ketamine Versus Dexmedetomidine to Bupivacaine in Pecs-ⅠⅠ Block on Postoperative Pain Control in Patients Undergoing Breast Surgery.
    The Clinical journal of pain, 2022, 09-01, Volume: 38, Issue:9

    Topics: Anesthetics, Local; Breast Neoplasms; Bupivacaine; Dexmedetomidine; Double-Blind Method; Female; Humans; Ketamine; Mastectomy; Morphine; Pain, Postoperative; Prospective Studies

2022
No Benefits of Adding Dexmedetomidine, Ketamine, Dexamethasone, and Nerve Blocks to an Established Multimodal Analgesic Regimen after Total Knee Arthroplasty.
    Anesthesiology, 2022, 10-01, Volume: 137, Issue:4

    Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Dexamethasone; Dexmedetomidine; Humans; Ketamine; Morphine; Nerve Block; Pain, Postoperative

2022
The Effect of Ultrasound-guided Bilateral Erector Spinae Plane Block With and Without Dexmedetomidine on Intraoperative and Postoperative Pain in Laparoscopic Cholecystectomies: A Randomized, Controlled, Double-blind, Prospective Trial.
    Pain physician, 2022, Volume: 25, Issue:7

    Topics: Analgesics, Opioid; Anesthetics, Local; Cholecystectomy, Laparoscopic; Dexmedetomidine; Humans; Morphine; Nerve Block; Pain, Postoperative; Postoperative Nausea and Vomiting; Prospective Studies; Remifentanil; Ropivacaine; Saline Solution; Ultrasonography, Interventional

2022
Immunosuppressive Effect of Intrathecal Morphine, Dexmedetomidine, or Both in Combination with Bupivacaine on Patients Undergoing Major Abdominal Cancer Surgery.
    Pain physician, 2022, Volume: 25, Issue:8

    Topics: Abdominal Neoplasms; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Dexmedetomidine; Double-Blind Method; Humans; Interleukin-10; Interleukin-6; Morphine; Pain, Postoperative; Prospective Studies; Tumor Necrosis Factor-alpha

2022
A randomised controlled trial of intravenous dexmedetomidine added to dexamethasone for arthroscopic rotator cuff repair and duration of interscalene block.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Anesthetics, Local; Arthroscopy; Brachial Plexus Block; Dexamethasone; Dexmedetomidine; Humans; Hypotension; Morphine; Pain, Postoperative; Rotator Cuff

2023
Sublingual dexmedetomidine (BXCL501) reduces opioid withdrawal symptoms: findings from a multi-site, phase 1b/2, randomized, double-blind, placebo-controlled trial.
    The American journal of drug and alcohol abuse, 2023, 01-02, Volume: 49, Issue:1

    Topics: Analgesics, Opioid; Animals; Cattle; Dexmedetomidine; Double-Blind Method; Female; Humans; Male; Morphine; Opioid-Related Disorders; Substance Withdrawal Syndrome; Treatment Outcome

2023
The role of dexmedetomidine as an adjuvant for high-thoracic erector spinae plane block for analgesia in shoulder arthroscopy; a randomized controlled study.
    BMC anesthesiology, 2023, 02-15, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Aged; Analgesia; Analgesics, Opioid; Arthroscopy; Bupivacaine; Dexmedetomidine; Female; Humans; Male; Middle Aged; Morphine; Nerve Block; Pain, Postoperative; Shoulder; Ultrasonography, Interventional; Young Adult

2023
Perioperative use of ketamine infusion versus dexmedetomidine infusion for analgesia in obese patients undergoing bariatric surgery: a double-blinded three-armed randomized controlled trial.
    BMC anesthesiology, 2023, 04-01, Volume: 23, Issue:1

    Topics: Analgesia; Analgesics, Opioid; Bariatric Surgery; Dexmedetomidine; Double-Blind Method; Fentanyl; Humans; Ketamine; Morphine; Obesity; Pain, Postoperative; Postoperative Nausea and Vomiting

2023
Effect of common sedation agents on feline splenic size determined via ultrasonography.
    New Zealand veterinary journal, 2023, Volume: 71, Issue:5

    Topics: Acepromazine; Animals; Cats; Dexmedetomidine; Hypnotics and Sedatives; Morphine; Spleen; Ultrasonography

2023

Other Studies

49 other study(ies) available for dexmedetomidine and morphine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Antinociception by epidural and systemic alpha(2)-adrenoceptor agonists and their binding affinity in rat spinal cord and brain.
    Anesthesia and analgesia, 2000, Volume: 90, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Algorithms; Analgesia, Epidural; Analgesics, Opioid; Animals; Brain; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Heart Rate; In Vitro Techniques; Injections, Intramuscular; Male; Morphine; Neurons; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord

2000
Antinociceptive action of epidural K+(ATP) channel openers via interaction with morphine and an alpha(2)- adrenergic agonist in rats.
    Anesthesia and analgesia, 2000, Volume: 90, Issue:5

    Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Analgesia; Analgesics, Opioid; Anesthetics, Combined; Animals; Cromakalim; Dexmedetomidine; Drug Interactions; Drug Synergism; Glyburide; Injections, Epidural; Ion Channel Gating; Male; Morphine; Naloxone; Narcotic Antagonists; Nicorandil; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley

2000
The effects of ketamine and its enantiomers on the morphine- or dexmedetomidine-induced antinociception after intrathecal administration in rats.
    Anesthesiology, 2000, Volume: 93, Issue:1

    Topics: Adrenergic alpha-Agonists; Analgesia; Analgesics; Analgesics, Opioid; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Injections, Spinal; Ketamine; Linear Models; Male; Morphine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stereoisomerism

2000
Effect of dexmedetomidine on the release of [3H]-noradrenaline from rat kidney cortex slices: characterization of alpha2-adrenoceptor.
    Neurochemistry international, 2001, Volume: 38, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Berberine; Chromatography, High Pressure Liquid; Dexmedetomidine; Dose-Response Relationship, Drug; Feedback; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Kidney Cortex; Male; Morphine; Norepinephrine; Piperazines; Prazosin; Prednisone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tritium

2001
Dexmedetomidine fails to cause hyperalgesia after cessation of chronic administration.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:1

    Topics: Adenylyl Cyclases; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Behavior, Animal; Dexmedetomidine; Dose-Response Relationship, Drug; Hot Temperature; Hyperalgesia; Ion Channels; Male; Mice; Mice, Inbred C57BL; Morphine; Pain Threshold; Physical Stimulation; Substance Withdrawal Syndrome

2003
A new method using flow cytometry to measure the effects of drugs on gastric emptying and gastrointestinal transit in mice.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:9

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Biomarkers; Dexmedetomidine; Flow Cytometry; Fluorescent Dyes; Gastric Emptying; Gastrointestinal Transit; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Morphine

2004
Synergistic and additive interactions of the cannabinoid agonist CP55,940 with mu opioid receptor and alpha2-adrenoceptor agonists in acute pain models in mice.
    British journal of pharmacology, 2005, Volume: 144, Issue:6

    Topics: Acute Disease; Adrenergic alpha-Agonists; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cannabinoids; Cyclohexanols; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Injections, Spinal; Male; Mice; Morphine; Pain; Pain Measurement; Receptors, Opioid, mu

2005
Long-term changes in the antinociceptive potency of morphine or dexmedetomidine after a single treatment.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:3

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Area Under Curve; Carrageenan; Dexmedetomidine; Drug Tolerance; Foot; Hot Temperature; Hyperalgesia; Inflammation; Male; Morphine; Pain Measurement; Rats; Rats, Wistar; Reaction Time; Time Factors

2005
Ketamine and N-acetylaspartylglutamate peptidase inhibitor exert analgesia in bone cancer pain.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:9

    Topics: Adrenergic alpha-Agonists; Analgesia; Animals; Bone Neoplasms; Dexmedetomidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ketamine; Male; Mice; Mice, Inbred C3H; Morphine; Pain, Intractable; Protease Inhibitors; Urea

2006
Intrathecal infusion therapy with dexmedetomidine-supplemented morphine in cancer pain.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:3

    Topics: Aged; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Dexmedetomidine; Drug Therapy, Combination; Humans; Male; Morphine; Neoplasms; Pain; Recurrence

2007
Translational research: addressing problems facing the anesthesiologist.
    Anesthesia and analgesia, 2007, Volume: 105, Issue:4

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesiology; Animals; Anterior Horn Cells; Biomedical Research; Dexmedetomidine; Humans; Morphine; Nerve Degeneration; Paraplegia; Rats; Spinal Cord Ischemia

2007
Intravenous infusion of dexmedetomidine can prevent the degeneration of spinal ventral neurons induced by intrathecal morphine after a noninjurious interval of spinal cord ischemia in rats.
    Anesthesia and analgesia, 2007, Volume: 105, Issue:4

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anterior Horn Cells; Dexmedetomidine; Dose-Response Relationship, Drug; Infusions, Intravenous; Injections, Spinal; Male; Morphine; Nerve Degeneration; Rats; Rats, Sprague-Dawley; Spinal Cord Ischemia

2007
Management of accidental spinal administration of extended-release epidural morphine.
    Anesthesiology, 2008, Volume: 108, Issue:6

    Topics: Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, Inhalation; Delayed-Action Preparations; Dexmedetomidine; Electroencephalography; Female; Humans; Injections, Spinal; Isoflurane; Medical Errors; Middle Aged; Monitoring, Intraoperative; Morphine; Naloxone; Narcotic Antagonists; Nitrous Oxide; Ovary; Postoperative Complications; Recovery of Function; Respiratory Insufficiency; Time Factors

2008
Dexmedetomidine and ST-91 analgesia in the formalin model is mediated by alpha2A-adrenoceptors: a mechanism of action distinct from morphine.
    British journal of pharmacology, 2008, Volume: 155, Issue:7

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Gene Expression Regulation; Injections, Spinal; Male; Morphine; Pain; Pain Measurement; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Neurokinin-1; Substance P

2008
[Incidence and duration of postoperative delirium after cardiac surgery : Comparison between dexmedetomidine and morphine for postoperative sedation and analgesia].
    Der Anaesthesist, 2010, Volume: 59, Issue:3

    Topics: Analgesics, Opioid; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Morphine; Pain, Postoperative; Postoperative Care; Postoperative Complications; Postoperative Period; Prospective Studies; Randomized Controlled Trials as Topic; Treatment Outcome

2010
Systemic daily morphine enhances the analgesic effect of intrathecal dexmedetomidine via up-regulation of alpha 2 adrenergic receptor subtypes A, B and C in dorsal root ganglion and dorsal horn.
    The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:12

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Dexmedetomidine; Ganglia, Spinal; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Morphine; Pain Measurement; Posterior Horn Cells; Receptors, Adrenergic, alpha-2; Spinal Cord; Up-Regulation

2010
Effects of alpha 2-adrenoceptor agonists dexmedetomidine and guanfacine on morphine analgesia and tolerance in rats.
    Upsala journal of medical sciences, 2011, Volume: 116, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Animals; Dexmedetomidine; Drug Tolerance; Guanfacine; Male; Morphine; Quinolizines; Rats; Rats, Wistar

2011
Suspected opioid-induced hyperalgesia in an infant.
    British journal of anaesthesia, 2012, Volume: 108, Issue:1

    Topics: Abdominal Wall; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Dissociative; Dexmedetomidine; Digestive System Surgical Procedures; Fentanyl; Humans; Hyperalgesia; Hypnotics and Sedatives; Infant, Newborn; Irritable Mood; Jejunostomy; Ketamine; Laparotomy; Male; Midazolam; Morphine; Pain Clinics; Pain Measurement; Photophobia; Reoperation

2012
Safety and efficacy of prolonged dexmedetomidine use in critically ill children with heart disease*.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2012, Volume: 13, Issue:6

    Topics: Blood Pressure; Child, Preschool; Critical Care; Critical Illness; Dexmedetomidine; Female; Heart Diseases; Heart Rate; Humans; Hypertension; Hypnotics and Sedatives; Infant; Length of Stay; Male; Midazolam; Morphine; Myocardial Contraction; Narcotics; Oxygen; Respiration, Artificial; Respiratory Rate; Retrospective Studies; Tachycardia; Time Factors

2012
The impact of dexmedetomidine infusion in sparing morphine consumption in off-pump coronary artery bypass grafting.
    Seminars in cardiothoracic and vascular anesthesia, 2013, Volume: 17, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Analgesics, Opioid; Coronary Artery Bypass, Off-Pump; Dexmedetomidine; Female; Humans; Intensive Care Units; Length of Stay; Male; Middle Aged; Morphine

2013
Impact of a protocol advocating dexmedetomidine over propofol sedation after robotic-assisted direct coronary artery bypass surgery on duration of mechanical ventilation and patient safety.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:4

    Topics: Aged; Analgesics, Opioid; Coronary Artery Bypass; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Morphine; Patient Safety; Postoperative Care; Propofol; Respiration, Artificial; Retrospective Studies; Robotics

2013
Reference values and repeatability of buccal mucosal bleeding time in healthy sedated cats.
    Journal of feline medicine and surgery, 2014, Volume: 16, Issue:2

    Topics: Analgesics, Opioid; Anesthetics, Dissociative; Animals; Bleeding Time; Blood Coagulation Tests; Cats; Dexmedetomidine; Hypnotics and Sedatives; Ketamine; Morphine; Mouth Mucosa; Reference Values; Reproducibility of Results

2014
Minimum end-tidal sevoflurane concentration necessary to prevent movement during a constant rate infusion of morphine, or morphine plus dexmedetomidine in ponies.
    Veterinary anaesthesia and analgesia, 2014, Volume: 41, Issue:2

    Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Dexmedetomidine; Drug Administration Schedule; Drug Therapy, Combination; Horses; Hypnotics and Sedatives; Injections, Intravenous; Methyl Ethers; Morphine; Sevoflurane

2014
The effect of four anaesthetic protocols for maintenance of anaesthesia on trans-diaphragmatic pressure in dogs.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Anesthesia; Anesthetics; Animals; Dexmedetomidine; Dogs; Female; Fentanyl; Isoflurane; Ketamine; Male; Morphine; Propofol

2013
Evaluation of dexmedetomidine and postoperative pain management in patients with adolescent idiopathic scoliosis: conclusions based on a retrospective study at a tertiary pediatric hospital.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2014, Volume: 15, Issue:6

    Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Critical Care; Dexmedetomidine; Elastomers; Female; Hospitals, Pediatric; Humans; Infusion Pumps; Infusions, Intralesional; Length of Stay; Male; Morphine; Pain Management; Pain, Postoperative; Polymers; Retrospective Studies; Scoliosis; Spinal Fusion; Tertiary Care Centers

2014
Sedation, analgesia, and anaesthesia variability in laboratory-based cardiac procedures: an international survey.
    The Canadian journal of cardiology, 2014, Volume: 30, Issue:6

    Topics: Anesthesia, General; Anesthesiology; Anesthetics, Intravenous; Attitude of Health Personnel; Benzodiazepines; Cardiovascular Surgical Procedures; Clinical Competence; Conscious Sedation; Deep Sedation; Dexmedetomidine; Diagnostic Techniques, Cardiovascular; Drug Utilization; Fentanyl; Humans; Hypnotics and Sedatives; Internationality; Morphine; Piperidines; Practice Patterns, Nurses'; Practice Patterns, Physicians'; Propofol; Remifentanil; Surveys and Questionnaires

2014
Dexmedetomidine as an adjuvant for perioperative pain management in adolescents undergoing bariatric surgery: An observational cohort study.
    Journal of pediatric surgery, 2017, Volume: 52, Issue:11

    Topics: Adolescent; Analgesics, Opioid; Bariatric Surgery; Cohort Studies; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Morphine; Obesity, Morbid; Pain Management; Pain, Postoperative

2017
Cardiorespiratory effects of epidural anesthesia using lidocaine with morphine or dexmedetomidine in capuchin monkeys (Sapajus sp.) undergoing bilateral tubal ligation surgery, anesthetized with isoflurane.
    Journal of medical primatology, 2017, Volume: 46, Issue:6

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Inhalation; Anesthetics, Local; Animals; Blood Pressure; Body Temperature; Cebinae; Dexmedetomidine; Female; Heart Rate; Isoflurane; Lidocaine; Lumbosacral Region; Morphine; Random Allocation; Sterilization, Tubal

2017
Dexmedetomidine Decreases Postoperative Pain and Narcotic Use in Children Undergoing Alveolar Bone Graft Surgery.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2018, Volume: 55, Issue:5

    Topics: Adolescent; Alveolar Bone Grafting; Analgesics, Non-Narcotic; Child; Cleft Palate; Dexmedetomidine; Drug Administration Schedule; Female; Humans; Ilium; Length of Stay; Male; Morphine; Narcotics; Pain Management; Pain Measurement; Pain, Postoperative; Retrospective Studies; Treatment Outcome

2018
Effects of dexmedetomidine combined with commonly administered opioids on clinical variables in dogs.
    American journal of veterinary research, 2018, Volume: 79, Issue:3

    Topics: Analgesics, Opioid; Animals; Butorphanol; Dexmedetomidine; Dogs; Drug Combinations; Female; Heart Rate; Male; Methadone; Morphine; Respiratory Rate; Tramadol

2018
Practice Change From Intermittent Medication Boluses to Bolusing From a Continuous Infusion in Pediatric Critical Care: A Quality Improvement Project.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2018, Volume: 19, Issue:6

    Topics: Atracurium; Child; Child, Preschool; Critical Care; Dexmedetomidine; Female; Fentanyl; Humans; Infant; Infusions, Intravenous; Injections, Intravenous; Intensive Care Units, Pediatric; Male; Midazolam; Morphine; Practice Patterns, Physicians'; Quality Improvement; Vecuronium Bromide

2018
Validation of the behavioral pain scale to assess pain intensity in adult, intubated postcardiac surgery patients: A cohort observational study - POL-BPS.
    Medicine, 2018, Volume: 97, Issue:38

    Topics: Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Behavior Observation Techniques; Cardiac Surgical Procedures; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Intensive Care Units; Intubation; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Poland; Prospective Studies; Self Report

2018
The impact of a quality improvement project to standardize pain, agitation, and withdrawal assessments on the use of morphine and midazolam in the Pediatric Intensive Care Unit.
    Paediatric anaesthesia, 2019, Volume: 29, Issue:4

    Topics: Analgesics, Opioid; Compliance; Conscious Sedation; Critical Care; Dexmedetomidine; Humans; Hypnotics and Sedatives; Iatrogenic Disease; Infant; Intensive Care Units; Length of Stay; Midazolam; Morphine; Pain Measurement; Quality Improvement; Substance Withdrawal Syndrome

2019
The Effectiveness of α2 Agonists As Sedatives in Pediatric Critical Care: A Propensity Score-Matched Cohort Study.
    Critical care medicine, 2019, Volume: 47, Issue:7

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Clinical Protocols; Clonidine; Dexmedetomidine; Equivalence Trials as Topic; Female; Humans; Hypnotics and Sedatives; Intensive Care Units, Pediatric; Male; Midazolam; Morphine; Propensity Score; Respiration, Artificial; Retrospective Studies; Single-Blind Method; Time Factors

2019
Evaluation of analgesic interaction between morphine, dexmedetomidine and maropitant using hot-plate and tail-flick tests in rats.
    Veterinary anaesthesia and analgesia, 2019, Volume: 46, Issue:4

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Antiemetics; Dexmedetomidine; Drug Synergism; Drug Therapy, Combination; Male; Morphine; Pain; Pain Measurement; Quinuclidines; Random Allocation; Rats; Rats, Sprague-Dawley

2019
Prone positioning without neuromuscular blockade during extracorporeal membrane oxygenation in children.
    Pediatrics international : official journal of the Japan Pediatric Society, 2020, Volume: 62, Issue:5

    Topics: Adolescent; Child; Child, Preschool; Chlorpromazine; Dexmedetomidine; Extracorporeal Membrane Oxygenation; Fentanyl; Humans; Hypnotics and Sedatives; Infant; Japan; Midazolam; Morphine; Neuromuscular Blockade; Prone Position; Respiratory Insufficiency; Retrospective Studies

2020
The indirect γ-aminobutyric acid (GABA) receptor agonist gabaculine-induced loss of the righting reflex may inhibit the descending analgesic pathway.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 198

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Baclofen; Cyclohexanecarboxylic Acids; Dexmedetomidine; GABA Agonists; Ganglia, Spinal; Male; Mice; Morphine; Muscimol; Neural Pathways; Neurons; Pain Measurement; Rats; Reflex, Righting; Signal Transduction; Spinal Cord; Substance P

2020
Does Treatment with Dexmedetomidine Intra-articularly Improve Postoperative Pain and Rehabilitation after Anterior Cruciate Ligament Reconstruction?
    The journal of knee surgery, 2022, Volume: 35, Issue:9

    Topics: Analgesics; Anesthetics, Local; Anterior Cruciate Ligament Reconstruction; Bupivacaine; Dexmedetomidine; Double-Blind Method; Humans; Levobupivacaine; Morphine; Pain, Postoperative

2022
Dexmedetomidine versus intermittent morphine for sedation of neonates with encephalopathy undergoing therapeutic hypothermia.
    Journal of perinatology : official journal of the California Perinatal Association, 2021, Volume: 41, Issue:9

    Topics: Brain Diseases; Cohort Studies; Dexmedetomidine; Humans; Hypothermia, Induced; Infant, Newborn; Morphine

2021
Evaluation of the perioperative stress response from dexmedetomidine infusion alone, with butorphanol bolus or remifentanil infusion compared with ketamine and morphine infusions in isoflurane-anesthetized horses.
    Veterinary anaesthesia and analgesia, 2021, Volume: 48, Issue:3

    Topics: Anesthesia Recovery Period; Animals; Butorphanol; Dexmedetomidine; Horses; Isoflurane; Ketamine; Morphine; Prospective Studies; Remifentanil

2021
Combined Cardiopulmonary Assessments Using Impedance and Digital Implants in Conscious Freely Moving Cynomolgus Monkeys, Beagle Dogs, and Göttingen Minipigs: Pharmacological Characterization and Social Housing Effects.
    International journal of toxicology, 2021, Volume: 40, Issue:6

    Topics: Amphetamine; Analgesics, Opioid; Animals; Cardiovascular System; Central Nervous System Stimulants; Dexmedetomidine; Dogs; Doxapram; Electric Impedance; Electrocardiography; Macaca fascicularis; Morphine; Swine; Swine, Miniature

2021
Reducing Benzodiazepine Exposure by Instituting a Guideline for Dexmedetomidine Usage in the NICU.
    Pediatrics, 2021, Volume: 148, Issue:5

    Topics: Airway Extubation; Analgesics, Opioid; Bradycardia; Dexmedetomidine; Drug Administration Schedule; Drug Substitution; Gestational Age; Humans; Hypnotics and Sedatives; Hypotension; Infant, Newborn; Intensive Care Units, Neonatal; Midazolam; Morphine; Outcome Assessment, Health Care; Quality Improvement; Time Factors

2021
EBNEO commentary: Dexmedetomidine versus morphine for neonates with encephalopathy undergoing therapeutic hypothermia.
    Acta paediatrica (Oslo, Norway : 1992), 2022, Volume: 111, Issue:9

    Topics: Dexmedetomidine; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Morphine

2022
Effects of opioid-free anesthesia on postoperative morphine consumption after bariatric surgery.
    Journal of clinical anesthesia, 2022, Volume: 81

    Topics: Analgesics, Opioid; Anesthesia; Bariatric Surgery; Clonidine; Dexmedetomidine; Humans; Morphine; Pain, Postoperative; Retrospective Studies

2022
Comparison of Liposomal Bupivacaine to a Local Analgesic Cocktail for Transversus Abdominis Plane Blocks in Abdominally Based Microvascular Breast Reconstruction.
    Plastic and reconstructive surgery, 2022, 09-01, Volume: 150, Issue:3

    Topics: Abdominal Muscles; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Dexmedetomidine; Female; Humans; Ketorolac; Mammaplasty; Morphine; Pain, Postoperative; Retrospective Studies

2022
A retrospective analysis of dexmedetomidine and morphine in the fast-track and ultra-fast-track extubation protocol after congenital cardiac surgery.
    Journal of cardiac surgery, 2022, Volume: 37, Issue:12

    Topics: Airway Extubation; Analgesics; Cardiac Surgical Procedures; Child; Dexmedetomidine; Humans; Hypnotics and Sedatives; Morphine; Retrospective Studies

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sedatives; Lorazepam; Morphine; Pain; Propofol; Retrospective Studies; Tracheotomy; Ventilators, Mechanical

2022
Single-Center Retrospective Comparison of Opioid-Based and Multimodal Analgesic Regimens in Adult Cardiac Surgery.
    Journal of cardiothoracic and vascular anesthesia, 2023, Volume: 37, Issue:7

    Topics: Adult; Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; Dexmedetomidine; Humans; Methadone; Morphine; Opioid-Related Disorders; Pain, Postoperative; Postoperative Nausea and Vomiting; Retrospective Studies

2023