dexmedetomidine has been researched along with methotrexate in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chen, J; Ding, H; Li, C; Wang, J; Xia, Z; Ye, J | 1 |
| Eldemerdash, OM; Elshaffei, IM; Senousy, MA; Taha, M; Yousef, EM | 1 |
1 review(s) available for dexmedetomidine and methotrexate
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 other study(ies) available for dexmedetomidine and methotrexate
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Dexmedetomidine reverses MTX-induced neurotoxicity and inflammation in hippocampal HT22 cell lines via NCOA4-mediated ferritinophagy.
Topics: Adrenergic alpha-2 Receptor Agonists; Autophagy; Cell Line; Cognitive Dysfunction; Dexmedetomidine; Ferritins; Hippocampus; Humans; Inflammation; Methotrexate; Neuroprotective Agents; Nuclear Receptor Coactivators | 2021 |
Dexmedetomidine Attenuates Methotrexate-Induced Neurotoxicity and Memory Deficits in Rats through Improving Hippocampal Neurogenesis: The Role of miR-15a/ROCK-1/ERK1/2/CREB/BDNF Pathway Modulation.
Topics: Animals; Brain-Derived Neurotrophic Factor; Dexmedetomidine; Hippocampus; Leucovorin; Male; MAP Kinase Signaling System; Memory Disorders; Methotrexate; MicroRNAs; Neurogenesis; Rats; Rats, Sprague-Dawley | 2023 |