dexmedetomidine has been researched along with malondialdehyde in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (6.12) | 29.6817 |
| 2010's | 29 (59.18) | 24.3611 |
| 2020's | 17 (34.69) | 2.80 |
| Authors | Studies |
|---|---|
| Hall, SR; Hong, M; Milne, B; Wang, L | 1 |
| Buyukbas, S; Cosar, M; Ela, Y; Eser, O; Fidan, H; Ozen, OA; Sahin, O; Yagmurca, M | 1 |
| Buyukbas, S; Cosar, M; Eser, O; Fidan, H; Mollaoglu, H; Sahin, O; Songur, A; Yaman, M | 1 |
| Acikgoz, B; Acikgoz, S; Ankarali, H; Bahadir, B; Bektas, S; Gul, S; Hanci, V; Kalayci, M | 1 |
| Bektaş, S; Can, M; Erol, B; Hanci, V; Mungan, G; Ozkoçak Turan, I; Tokgöz, H; Yurtlu, S | 1 |
| Huang, WQ; Li, Y; Li, YS; Liu, KX; Liu, ZM; Wen, SH; Yao, X; Zhang, XY | 1 |
| Citil, M; Hanci, V; Kiliç, K; Kiliç, N; Selek, S; Sözmen, M; Yurtlu, BS; Yurtlu, DA | 1 |
| Afyoncu, E; Başar, H; Cuzdan, SS; Fidancı, V; Gülbahçe, R; Kayıran, O; Üstün, H; Uysal, HY | 1 |
| Akcay, F; Calik, M; Cetin, N; Gundogdu, C; Ingec, M; Isaoglu, U; Kurt, A; Polat, B; Suleyman, H; Yilmaz, M | 1 |
| Ayoglu, H; Bostankolu, E; Can, M; Deniz, Y; Erdogan, G; Hanci, V; Okyay, RD; Turan, IO; Yurtlu, S | 1 |
| Akkuş, M; Altekin, E; Cilaker Mıcılı, S; Duru, S; Ergür, BU; Girgin, P; Gündüz, K; Güzeldağ, S; Koca, U; Olguner, ÇG; Taşdöğen, A | 1 |
| Kan, MC; Li, JT; Ma, WQ; Wang, W; Wang, WP; Xie, T; Yao, GD | 1 |
| Alkanat, M; Besir, A; Cekic, B; Geze, S; Yulug, E | 1 |
| Dong, X; Han, X; Li, Y; Sun, L; Xing, Q | 1 |
| Deveci, E; Doğan, E; Ece, A; Güzel, A; Kaplan, İ; Şen, HS; Sen, V; Söker, S; Uluca, U | 1 |
| Bendix, I; Bührer, C; Endesfelder, S; Krain, M; Paeschke, N; Sifringer, M; Spies, CD; von Haefen, C | 1 |
| Cheung, CW; Li, S; Qian, L; Wu, Y; Yang, Y; Yao, Y; Yu, C | 1 |
| Alkan, M; Arslan, M; Bilge, M; Çelik, A; Erdem, Ö; Kavutçu, M; Kip, G; Kiraz, HA; Özer, A; Şıvgın, V | 1 |
| Chen, YJ; Gong, CL; Tan, F; Zhou, SL | 1 |
| Chen, JH; Jin, SY; Lei, DX; Song, XR; Yu, GF; Zhang, WH; Zhou, SL | 1 |
| Fu, G; Jiang, L; Li, L; Shen, J | 1 |
| Akdogan, A; Bahat, Z; Besir, A; Canyilmaz, E; Demirci, Y; Erturk, E; Kara, H; Kayir, S; Kutanis, D; Vanizor Kural, B | 1 |
| Akpınar, H; Akpınar, O; Nazıroğlu, M | 1 |
| Han, F; Liu, Z; Ning, Q; Sun, H; Wang, X; Yang, M; Zhang, J; Zhang, R; Zhang, X; Zhao, W | 1 |
| Li, Y; Liu, S | 1 |
| Huang, SQ; Kang, XH; Liu, L; Wu, XM; Yu, Y; Zhang, J; Zhang, XX; Zhu, SM | 1 |
| Guo, YB; Ji, XX; Liang, JX; Xu, JD; Zhang, JX; Zhou, GB | 1 |
| Pang, Q; Wang, Z; Zhou, W; Zhou, X; Zhou, Y | 1 |
| Ding, M; Li, JY; Ren, HC; Wang, G; Wang, Q; Weng, YQ; Xu, RB; Yu, HL; Yu, WL | 1 |
| Chen, Y; Dai, JC; Du, J; Fan, X; Li, JM; Wang, MH; Yang, B; Zhang, C; Zhou, J | 1 |
| Lu, J; Wu, C; Zhou, D; Zhou, H; Zhu, Z | 1 |
| Choi, YS; Kim, SH | 1 |
| Cheng, W; Liu, P; Liu, X; Wang, M; Wang, X; Zhao, S | 1 |
| Bian, W; Chen, Y; Xu, B | 1 |
| He, J; Kang, L; Ni, J; Wang, L; Yin, S; Zhong, Z | 1 |
| Huang, Q; Kong, Q; Ming, T; Wu, X; Xia, Z; Yuan, M | 1 |
| Gong, Z; Li, J; Long, X; Ma, L; Tang, Y; Wei, H; Yu, J | 1 |
| Cui, E; Li, M; Sun, J; Yan, M; Zhang, H; Zhang, Y; Zhou, J; Zhu, X | 1 |
| Cheng, M; Dong, W; Huang, G; Yang, H; Yin, J; Zeng, Z; Zhang, X | 1 |
| Deresoy, FA; Firat, F; Katar, M; Kölükçü, E; Kölükçü, V; Kuyucu, YE; Parlaktaş, BS; Unsal, V | 1 |
| Delen, LA; Gulaboglu, M; Kuyrukluyildiz, U; Onk, D; Suleyman, H; Yazici, GN | 1 |
| Guo, M; Hu, C; Qin, K; Shen, Z; Wang, F; Xie, X; Zhang, K | 1 |
| Huang, J; Ji, M; Wang, J | 1 |
| Chen, C; Guo, B; Yang, L; Zhu, R | 1 |
| Huang, Z; Liu, G; Shan, R; Sun, C; Wang, G; Wang, L; Zhang, X; Zhong, Y | 1 |
| Ergene, S; Hemsinli, D; Karakisi, SO; Mercantepe, T; Tumkaya, L; Yilmaz, A | 1 |
| Li, G; Liu, B; Wei, J; Zhou, J | 1 |
| Gao, S; Guan, S; Ma, G; Zhang, J; Zhou, L | 1 |
| Lu, SJ; Qi, QL; Wang, HY; Zhang, YJ | 1 |
1 review(s) available for dexmedetomidine and malondialdehyde
| Article | Year |
|---|---|
Can Dexmedetomidine Improve Arterial Oxygenation and Intrapulmonary Shunt during One-lung Ventilation in Adults Undergoing Thoracic Surgery? A Meta-analysis of Randomized, Placebo-controlled Trials.
Topics: Blood Gas Analysis; Dexmedetomidine; Humans; Interleukin-6; Malondialdehyde; One-Lung Ventilation; Randomized Controlled Trials as Topic; Superoxide Dismutase; Thoracic Surgery; Tumor Necrosis Factor-alpha | 2017 |
9 trial(s) available for dexmedetomidine and malondialdehyde
| Article | Year |
|---|---|
Dexmedetomidine did not reduce the effects of tourniquet-induced ischemia-reperfusion injury during general anesthesia.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Anesthesia, General; Antioxidants; Dexmedetomidine; Drug Administration Schedule; Female; Humans; Lipid Peroxidation; Lower Extremity; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Reperfusion Injury; Tourniquets | 2013 |
Dexmedetomidine Analgesia Effects in Patients Undergoing Dental Implant Surgery and Its Impact on Postoperative Inflammatory and Oxidative Stress.
Topics: Adult; Analgesics, Non-Narcotic; Dental Implants; Dexmedetomidine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypnotics and Sedatives; Inflammation; Interleukin-6; Male; Malondialdehyde; Midazolam; Middle Aged; Oxidative Stress; Pain; Postoperative Complications; Severity of Illness Index; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2015 |
[Protective effect of dexmedetomidine against perioperative inflammation and on pulmonary function in patients undergoing radical resection of lung cancer].
Topics: Anesthesia; Dexmedetomidine; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Interleukin-10; Interleukin-1beta; Lung; Lung Neoplasms; Malondialdehyde; Partial Pressure; Peroxidase; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 2017 |
Effects of Pre-Cardiopulmonary Bypass Administration of Dexmedetomidine on Cardiac Injuries and the Inflammatory Response in Valve Replacement Surgery With a Sevoflurane Postconditioning Protocol: A Pilot Study.
Topics: Aged; Anti-Inflammatory Agents; Biomarkers; Cardiopulmonary Bypass; China; Cytokines; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Female; Heart Valve Prosthesis Implantation; Humans; Inflammation; Inflammation Mediators; Male; Malondialdehyde; Middle Aged; Myocardial Reperfusion Injury; Pilot Projects; Prospective Studies; Sevoflurane; Superoxide Dismutase; Time Factors; Treatment Outcome; Troponin I | 2019 |
[Dexmedetomidine combined with protective lung ventilation strategy provides lung protection in patients undergoing radical resection of esophageal cancer with one-lung ventilation].
Topics: Dexmedetomidine; Esophageal Neoplasms; Humans; Lung; Malondialdehyde; One-Lung Ventilation | 2020 |
Effects of dexmedetomidine combined with citrate sufentanil on the prognosis of patients with severe pneumonia and respiratory failure requiring mechanical ventilation.
Topics: Aged; Analgesics, Opioid; Dexmedetomidine; Drug Therapy, Combination; Female; Hospital Mortality; Humans; Hypnotics and Sedatives; Interleukin-6; Male; Malondialdehyde; Middle Aged; Oxygen; Partial Pressure; Pneumonia; Prognosis; Respiration, Artificial; Respiratory Insufficiency; Severity of Illness Index; Sufentanil; Tumor Necrosis Factor-alpha | 2021 |
Assessment of the effect of perineural dexmedetomidine on oxidative stress during peritoneal dialysis catheter insertion: a randomized, controlled trial.
Topics: Anesthetics, Local; Catheters; Dexmedetomidine; Glutathione Peroxidase; Humans; Kidney Failure, Chronic; Malondialdehyde; Nerve Block; Oxidative Stress; Peritoneal Dialysis; Prospective Studies; Ropivacaine; Superoxide Dismutase; Ultrasonography, Interventional | 2022 |
Dexmedetomidine attenuates pneumocyte apoptosis and inflammation induced by aortic ischemia-reperfusion injury.
Topics: Adrenergic Agonists; Alveolar Epithelial Cells; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Dexmedetomidine; Glutathione; Inflammation; Malondialdehyde; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2022 |
Effects of Dexmedetomidine Pretreatment, Posttreatment, and Whole-Course Pumping on Myocardial Damage during Cardiac Valve Replacement.
Topics: Dexmedetomidine; Dopamine; Heart Valves; Humans; Malondialdehyde; Sufentanil; Troponin I; Tumor Necrosis Factor-alpha | 2022 |
39 other study(ies) available for dexmedetomidine and malondialdehyde
| Article | Year |
|---|---|
Central dexmedetomidine attenuates cardiac dysfunction in a rodent model of intracranial hypertension.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Catecholamines; Dexmedetomidine; Disease Models, Animal; Electrocardiography; Heart Diseases; Heart Function Tests; Heart Rate; Hemodynamics; Intracranial Hypertension; Male; Malondialdehyde; Norepinephrine; Rats; Rats, Sprague-Dawley; Time Factors; Ventricular Function, Left | 2004 |
The neuroprotective effect of dexmedetomidine in the hippocampus of rabbits after subarachnoid hemorrhage.
Topics: Animals; Antioxidants; Dexmedetomidine; Hippocampus; Male; Malondialdehyde; Neuroprotective Agents; Oxidants; Rabbits; Subarachnoid Hemorrhage; Superoxide Dismutase; Vasospasm, Intracranial; Xanthine Oxidase | 2009 |
The influence of dexmedetomidine on ischemic rat hippocampus.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Catalase; Cytokines; Dexmedetomidine; Disease Models, Animal; Hippocampus; In Situ Nick-End Labeling; Ischemia; Male; Malondialdehyde; Neurons; Nitric Oxide; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2008 |
The effectiveness of dexmedetomidine in experimental spinal cord injury compared to methylprednisolone in rats.
Topics: Animals; Aryldialkylphosphatase; Cholesterol, HDL; Dexmedetomidine; Lipid Peroxidation; Male; Malondialdehyde; Methylprednisolone; Neuroprotective Agents; Rats; Rats, Wistar; Spinal Cord Injuries | 2010 |
Effect of dexmedetomidine on testicular torsion/detorsion damage in rats.
Topics: Animals; Antioxidants; Apoptosis; Apoptotic Protease-Activating Factor 1; Dexmedetomidine; Germ Cells; Ischemia; Male; Malondialdehyde; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Reperfusion Injury; Spermatic Cord Torsion; Testis | 2010 |
Dexmedetomidine administration before, but not after, ischemia attenuates intestinal injury induced by intestinal ischemia-reperfusion in rats.
Topics: Adrenergic alpha-Agonists; Amine Oxidase (Copper-Containing); Animals; Apoptosis; Blood Gas Analysis; Caspase 3; Dexmedetomidine; Dose-Response Relationship, Drug; Hemodynamics; Intestinal Mucosa; Intestines; Lactic Acid; Male; Malondialdehyde; Peroxidase; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reperfusion Injury; Survival Analysis; Tumor Necrosis Factor-alpha | 2012 |
The effects of dexmedetomidine on mesenteric arterial occlusion-associated gut ischemia and reperfusion-induced gut and kidney injury in rabbits.
Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Animals; Antioxidants; Arterial Occlusive Diseases; Dexmedetomidine; Disease Models, Animal; Intestinal Mucosa; Intestines; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Mesenteric Arteries; Oxidants; Peroxidase; Rabbits; Reperfusion Injury; Treatment Outcome | 2012 |
Preventive effect of dexmedetomidine in ischemia-reperfusion injury.
Topics: Analysis of Variance; Animals; Dexmedetomidine; Malondialdehyde; Nitric Oxide; Peroxidase; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Statistics, Nonparametric; Surgical Flaps | 2012 |
An investigation about the inhibition of acute ischemia/reperfusion damage by dexmedetomidine in rat ovarian tissue.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Biomarkers; Dexmedetomidine; DNA Damage; Female; Glutathione; Guanine; Ischemia; Lipid Peroxidation; Malondialdehyde; Ovary; Protective Agents; Rats; Rats, Wistar; Reperfusion Injury; Yohimbine | 2013 |
The effects of dexmedetomidine on secondary acute lung and kidney injuries in the rat model of intra-abdominal sepsis.
Topics: Acute Kidney Injury; Acute Lung Injury; Acute-Phase Proteins; Animals; Apoptosis; Caspase 3; Cecum; Cell Count; Creatinine; Dexmedetomidine; Disease Models, Animal; DNA Fragmentation; Kidney; Lipocalin-2; Lipocalins; Lung; Macrophages, Alveolar; Male; Malondialdehyde; Proto-Oncogene Proteins; Rats; Rats, Wistar; Sepsis | 2013 |
Anticonvulsant effect of dexmedetomidine in a rat model of self-sustaining status epilepticus with prolonged amygdala stimulation.
Topics: Adrenergic alpha-2 Receptor Agonists; Amygdala; Animals; Anticonvulsants; Dexmedetomidine; Electric Stimulation; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Hippocampus; Male; Malondialdehyde; Rats; Rats, Wistar; Status Epilepticus | 2013 |
Protective effects of dexmedetomidine in pneumoperitoneum-related ischaemia-reperfusion injury in rat ovarian tissue.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Drug Evaluation, Preclinical; Female; Malondialdehyde; Ovarian Diseases; Ovary; Pneumoperitoneum, Artificial; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2013 |
Dexmedetomidine protects against ischemia-reperfusion injury in rat skeletal muscle.
Topics: Animals; Catalase; Dexmedetomidine; Glutathione; Interleukin-1beta; Malondialdehyde; Muscle, Skeletal; Rats; Rats, Wistar; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2014 |
Preventive effects of dexmedetomidine on the liver in a rat model of acid-induced acute lung injury.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Dexmedetomidine; Gene Expression Regulation; Humans; Hydrochloric Acid; Liver; Malondialdehyde; Oxidative Stress; Rats; Vascular Endothelial Growth Factor A | 2014 |
Neuroprotective effect of dexmedetomidine on hyperoxia-induced toxicity in the neonatal rat brain.
Topics: Animals; Animals, Newborn; Apoptosis; Brain Injuries; Dexmedetomidine; Disease Models, Animal; Down-Regulation; Glutathione; Hyperoxia; Interleukin-1beta; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Rats; Rats, Wistar | 2015 |
Dexmedetomidine protects from post-myocardial ischaemia reperfusion lung damage in diabetic rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Diabetes Mellitus, Experimental; Glutathione Transferase; Lung; Lung Injury; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Random Allocation; Rats; Rats, Wistar | 2015 |
[Pretreatment with dexmedetomidine ameliorates renal inflammation and oxidative stress in rats with lipopolysaccharide-induced sepsis and acute kidney injury].
Topics: Acute Kidney Injury; Animals; Dexmedetomidine; Inflammation; Interleukin-1beta; Kidney; Lipopolysaccharides; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sepsis; Superoxide Dismutase | 2015 |
Activation of α2 adrenoceptor attenuates lipopolysaccharide-induced hepatic injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Dexmedetomidine; Disease Models, Animal; Interleukin-1beta; Interleukin-6; Lactic Acid; Lipopolysaccharides; Liver; Male; Malondialdehyde; Oxidative Stress; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Sepsis; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha; Yohimbine | 2015 |
[Effect of dexmedetomidine hydrochloride on H2O2-induced oxidative stress and inflammatory response in Kupffer cells].
Topics: Adrenergic alpha-2 Receptor Antagonists; Cell Survival; Cells, Cultured; Dexmedetomidine; Humans; Hydrogen Peroxide; Kupffer Cells; L-Lactate Dehydrogenase; Malondialdehyde; Oxidative Stress; Receptors, Adrenergic, alpha-2; Tumor Necrosis Factor-alpha; Yohimbine | 2016 |
Dexmedetomidine acts as an oxidative damage prophylactic in rats exposed to ionizing radiation.
Topics: Analgesics, Non-Narcotic; Animals; Antioxidants; Biomarkers; Catalase; Dexmedetomidine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Kidney; Liver; Lung; Male; Malondialdehyde; Oxidative Stress; Oxidoreductases; Prospective Studies; Radiation Injuries, Experimental; Radiation, Ionizing; Random Allocation; Rats; Rats, Sprague-Dawley; Serum Albumin; Serum Albumin, Human; Superoxide Dismutase; Thyroid Gland | 2016 |
Different doses of dexmedetomidine reduce plasma cytokine production, brain oxidative injury, PARP and caspase expression levels but increase liver oxidative toxicity in cerebral ischemia-induced rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain; Brain Ischemia; Caspase 1; Cytokines; Dexmedetomidine; Disease Models, Animal; Glutathione; Inflammation Mediators; Liver; Male; Malondialdehyde; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Rats, Wistar | 2017 |
Neurodegenerative changes and neuroapoptosis induced by systemic lipopolysaccharide administration are reversed by dexmedetomidine treatment in mice.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Brain Diseases; Dexmedetomidine; Disease Models, Animal; Interleukin-1beta; Lipopolysaccharides; Male; Malondialdehyde; Mice, Inbred BALB C; Neurodegenerative Diseases; Neuroimmunomodulation; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Reactive Oxygen Species; Sepsis; Tumor Necrosis Factor-alpha | 2017 |
The Effect of Dexmedetomidine on Oxidative Stress Response Following Cerebral Ischemia-Reperfusion in Rats and the Expression of Intracellular Adhesion Molecule-1 (ICAM-1) and S100B.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Dexmedetomidine; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; S100 Calcium Binding Protein beta Subunit; Superoxide Dismutase | 2017 |
The protective effect of dexmedetomidine in a rat ex vivo lung model of ischemia-reperfusion injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Blotting, Western; CCAAT-Enhancer-Binding Proteins; Dexmedetomidine; Disease Models, Animal; Heat-Shock Proteins; Ischemia; Lung; Male; Malondialdehyde; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reference Values; Reperfusion Injury; Reproducibility of Results; Superoxide Dismutase; Time Factors; Treatment Outcome | 2018 |
Protective effect of ulinastatin combined with dexmedetomidine on lung injury after cold ischemia-reperfusion in rats.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Cold Ischemia; Cytokines; Cytoprotection; Dexmedetomidine; Disease Models, Animal; Glycoproteins; Inflammation Mediators; Lipid Peroxidation; Liver Transplantation; Lung; Male; Malondialdehyde; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase | 2018 |
Irisin Contributes to the Hepatoprotection of Dexmedetomidine during Intestinal Ischemia/Reperfusion.
Topics: Alanine Transaminase; Animals; Antibodies, Neutralizing; Aspartate Aminotransferases; Dexmedetomidine; Fibronectins; Intestines; Ischemia; Liver; Male; Malondialdehyde; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2019 |
Effects of dexmedetomidine on malondialdehyde and proinflammatory cytokines after tourniquet-induced ischemia-reperfusion injury in total knee arthroplasty.
Topics: Arthroplasty, Replacement, Knee; Cytokines; Dexmedetomidine; Humans; Malondialdehyde; Reperfusion Injury; Tourniquets | 2020 |
Protective Effects of Dexmedetomidine and Oxycodone in Patients Undergoing Limb Ischemia-Reperfusion.
Topics: Adult; Aged; Brain-Derived Neurotrophic Factor; China; Dexmedetomidine; Endothelin-1; Fatty Acid Binding Protein 3; Female; Hemodynamics; Humans; Interleukin-6; Ischemia; Lower Extremity; Male; Malondialdehyde; Middle Aged; Oxycodone; Peripheral Vascular Diseases; Prospective Studies; Random Allocation; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2019 |
Pretreatment with dexmedetomidine alleviates lung injury in a rat model of intestinal ischemia reperfusion.
Topics: Acute Lung Injury; Animals; Antioxidants; Cytokines; Dexmedetomidine; Disease Models, Animal; Heme Oxygenase-1; Lung; Male; Malondialdehyde; NF-E2 Transcription Factor; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Superoxide Dismutase | 2020 |
Effects of dexmedetomidine pretreatment on rats with sepsis-induced acute kidney injury and miR-146a expression.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Catalase; Creatinine; Dexmedetomidine; Heme Oxygenase (Decyclizing); Interleukin-1beta; Interleukin-6; Kidney; Lipopolysaccharides; Malondialdehyde; MicroRNAs; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sepsis; Superoxide Dismutase | 2020 |
Dexmedetomidine alleviates blunt chest trauma and hemorrhagic shock‑resuscitation‑induced acute lung injury through inhibiting the NLRP3 inflammasome.
Topics: Acute Lung Injury; Animals; Cytokines; Dexmedetomidine; Disease Models, Animal; Gene Expression Regulation; Injections, Intraperitoneal; L-Lactate Dehydrogenase; Male; Malondialdehyde; NLR Family, Pyrin Domain-Containing 3 Protein; Peroxidase; Rats; Resuscitation; Shock, Hemorrhagic; Signal Transduction; Superoxide Dismutase; Thoracic Injuries; Wounds, Nonpenetrating | 2020 |
Dexmedetomidine attenuates sevoflurane‑induced neurocognitive impairment through α2‑adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Caspase 3; Cognitive Dysfunction; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Morris Water Maze Test; Random Allocation; Sevoflurane; Superoxide Dismutase; Treatment Outcome; Yohimbine | 2021 |
Dexmedetomidine alleviates pulmonary ischemia-reperfusion injury through modulating the miR-21-5p/Nr4a1 signaling pathway.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Base Pairing; Base Sequence; Caspase 3; Caspase 9; Cell Survival; Dexmedetomidine; Endothelial Cells; Female; Gene Expression Regulation; HEK293 Cells; Humans; Lung; Malondialdehyde; Mice; Mice, Inbred C57BL; MicroRNAs; Nuclear Receptor Subfamily 4, Group A, Member 1; Reperfusion Injury; Signal Transduction | 2020 |
Protective effects of dexmedetomidine on ischaemia-reperfusion injury in an experimental rat model of priapism.
Topics: Animals; Dexmedetomidine; Humans; Male; Malondialdehyde; Priapism; Rats; Reperfusion Injury; Superoxide Dismutase | 2021 |
The effect of dexmedetomidine on gastric ischemia reperfusion injury in rats. Biochemical and histopathological evaluation.
Topics: Animals; Antioxidants; Dexmedetomidine; Male; Malondialdehyde; Rats; Rats, Wistar; Reperfusion Injury; Stomach; Superoxide Dismutase | 2021 |
Dexmedetomidine Ameliorates Postoperative Cognitive Dysfunction in Aged Mice.
Topics: Abdomen; Animals; Anti-Inflammatory Agents; Antioxidants; Brain-Derived Neurotrophic Factor; Cyclin-Dependent Kinase 5; Cytokines; Dexmedetomidine; Hippocampus; Male; Malondialdehyde; Mice, Inbred C57BL; Microglia; Morris Water Maze Test; Neuroprotective Agents; Open Field Test; Postoperative Cognitive Complications; Superoxide Dismutase | 2021 |
Effects of dexmedetomidine on postoperative cognitive function of sleep deprivation rats based on changes in inflammatory response.
Topics: Animals; Cognition; Dexmedetomidine; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Male; Malondialdehyde; Morris Water Maze Test; Neuropeptides; NF-kappa B; Oxidative Stress; Postoperative Complications; Proto-Oncogene Proteins c-akt; rac1 GTP-Binding Protein; Random Allocation; Rats; Rats, Sprague-Dawley; Sleep Deprivation; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2021 |
Dexmedetomidine Ameliorated Cognitive Dysfunction Induced by Intestinal Ischemia Reperfusion in Mice with Possible Relation to the Anti-inflammatory Effect Through the Locus Coeruleus Norepinephrine System.
Topics: Adrenergic Antagonists; Animals; Anti-Inflammatory Agents; Benzylamines; Cognitive Dysfunction; Dexmedetomidine; Eosine Yellowish-(YS); Hematoxylin; Ischemia; Locus Coeruleus; Malondialdehyde; Mice; Neuroprotective Agents; Neurotoxins; Norepinephrine; Reperfusion; Reperfusion Injury; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase; Yohimbine | 2022 |
Effects of electroacupuncture with dexmedetomidine on myocardial ischemia/reperfusion injury in rats.
Topics: Adenosine Triphosphate; Animals; Dexmedetomidine; Electroacupuncture; Male; Malondialdehyde; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 2022 |