dexmedetomidine has been researched along with lidocaine in 111 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (9.91) | 29.6817 |
| 2010's | 58 (52.25) | 24.3611 |
| 2020's | 42 (37.84) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Karamanlioğlu, B; Kurt, I; Memiş, D; Pamukçu, Z; Turan, A | 1 |
| Karamanlioglu, B; Kaya, G; Memis, D; Turan, A | 1 |
| Akin, A; Boyaci, A; Esmaoglu, A; Mizrak, A; Turk, Y | 1 |
| Vandermeulen, E | 1 |
| Dohi, S; Iida, H; Oda, A; Osawa, Y; Tanahashi, S; Yamaguchi, S | 1 |
| Adanir, T; Konakci, S; Rezanko, T; Yilmaz, G | 1 |
| Dohi, S; Ohata, H; Tanemura, E | 1 |
| Higuchi, H; Kohjitani, A; Maeda, S; Miyawaki, T; Shimada, M; Yoshitomi, T | 1 |
| Shapiro, FE | 1 |
| Goyagi, T; Masaki, Y; Nishikawa, T; Tobe, Y | 1 |
| Alptekin, M; Erkutlu, I; Gul, R; Mizrak, A; Oner, U | 1 |
| Cortopassi, SR; De Biaggi, CP; Dias, RA; Intelisano, TR; Moura, CA; Selmi, AL; Souza, SS | 1 |
| Ayoğlu, H; Baydilek, Y; Erdoğan, G; Hanci, V; Okyay, RD; Turan, IO; Yurtlu, BS | 1 |
| Kanai, T; Maruta, T; Nemoto, T; Satoh, S; Tsuneyoshi, I; Wada, A; Yanagita, T | 1 |
| Bednarski, RM; Ebner, LS; Hubbell, JA; Lerche, P | 1 |
| Acevedo-Arcique, CM; Bolio-González, ME; Gutierrez-Blanco, E; Ibancovichi-Camarillo, JA; Marin-Cano, G; Sauri-Arceo, CH; Steagall, PV; Victoria-Mora, JM | 2 |
| Chiavaccini, L; Claude, AK; Meyer, RE | 1 |
| Koga, Y; Nakao, S; Ouchi, K; Sugiyama, K | 1 |
| Acevedo-Arcique, CM; Gutierrez-Blanco, E; Ibancovichi, JA; Moran-Muñoz, R; Santos-Gonzalez, M; Tendillo, FJ; Victoria Mora, JM; Yamashita, K | 1 |
| Dong, C; Lu, Y; Yu, J; Zhang, Y | 1 |
| Acevedo-Arcique, CM; Chavez, JR; Gutierrez-Blanco, E; Ibancovichi, JA; Moran-Muñoz, R; Sanchez-Aparicio, P; Santos-González, M; Tendillo-Cortijo, F; Victoria-Mora, JM | 1 |
| Haga, HA; Krontveit, R; Ranheim, B; Risberg, A; Spadavecchia, C | 1 |
| Cho, HS; Kim, CS; Kim, E; Kim, G; Kim, HJ; Kim, WH; Lee, YT; Park, MH; Shin, BS; Sim, WS | 1 |
| Higuchi, H; Ishii-Maruhama, M; Maeda, S; Miyawaki, T; Tomoyasu, Y; Yamane, A | 1 |
| Burat, I; Dalkilic, N; Tuncer, S | 1 |
| Akimoto, T; Hashimoto, S; Sunada, K | 1 |
| Harsoor, SS; Lathashree, S; Nethra, SS; Rani, D; Roopa, MN; Sudheesh, K | 1 |
| Candiotti, K; de Marchena, E; Degnan, M; Palermo, C; Rodriguez-Blanco, Y; Salerno, T | 1 |
| Li, Y; Lu, Y; Lv, G; Sun, J; Wang, G; Wang, H; Zhuang, X | 1 |
| Budhraja, N; Khandaitkar, S; Kolte, V; Shenoi, SR | 1 |
| Kim, JY; Kim, YB; Kwak, HJ; Lee, SY; Park, CK; Yoo, JY | 1 |
| Brudney, CS; Ehieli, E; Pyati, S; Yalamuri, S | 1 |
| Chen, SB; Hou, BC; Huang, J; Liu, WC; Luo, XL; Wang, XF; Zhan, YP | 1 |
| Halaszynski, T; Hu, X; Li, J; Wang, Q; Xia, F; Xu, X; Zhou, R | 1 |
| DeBlieux, PM; Tonna, JE | 1 |
| Bilotta, F; Logan, SW; Tsaousi, GG | 1 |
| Hu, SH; Ju, X; Li, YH; Wang, SB; Xiao, JB; Xu, SQ | 1 |
| Buisman, M; Gunn, M; Hasiuk, MMM; Pang, DSJ | 1 |
| Jin, S; Li, X; Li, Y; Wang, X; Zhang, D | 1 |
| Emala, CW; Groeben, H; Kim, B; Mikami, M; Worgall, TS; Zhang, Y | 1 |
| Matute Crespo, M; Montero Matamala, A | 1 |
| Bi, X; Ruan, X; She, Y; Tan, Y; Wang, Q; Zhao, B | 1 |
| Adami, C; Fernandez-Parra, R; Fontaine, C; Zilberstein, L | 1 |
| Bi, X; Ruan, X; She, Y; Tan, Y; Wang, Q; Wei, W; Xu, Y; Zhang, N; Zhao, B | 1 |
| Elsersy, HE; Sherif, AA | 1 |
| Aoun, Z; Bazarbachi, T; Dabar, G; Habr, B; Ibrahim, I; Khalil, N; Khayat, G; Riachy, M | 1 |
| Barbosa, VF; de Araujo, NLLC; Dórea Neto, FA; Martins Filho, EF; Oriá, AP; Otero, AR; Schäffer, DPH | 1 |
| Liu, J; Yang, L; Yin, Q; Zhang, W; Zhao, W | 1 |
| Kumar, A; Madan, K; Mittal, S; Mohan, A | 1 |
| Clendenen, SR | 1 |
| Sunada, K; Tsutsui, Y | 3 |
| Bindra, A; Chouhan, RS; Radhakrishna, N; Singh, S | 1 |
| Kirti, S; Kumar, P; Priya, K; Singh, V; Thepra, M | 1 |
| Andjelković, L; Bosnić, Z; Novak-Jankovič, V; Požar-Lukanovič, N; Spindler-Vesel, A | 1 |
| Kawaai, H; Tada, H; Togami, K; Tomita, S; Yamazaki, S | 1 |
| She, Y; Song, X; Xu, H; Zhao, B | 1 |
| Chung, W; Hong, B; Jo, Y; Jung, C; Kang, H; Kim, YH; Ko, Y; Lim, C | 1 |
| Matsumoto, Y; Murakami, Y; Nakata, M; Torumi, T; Yoshimura, M | 1 |
| Chang, WS; Choi, SH; Ha, SH; Heo, GA; Jeong, J; Kim, H; Min, KT | 1 |
| Gao, YT; Liu, XF | 1 |
| Li, H; Li, SY; Ma, YS; Ni, J | 1 |
| Hu, S; Ju, X; Li, Y; Ma, L; Wang, S; Xu, S | 1 |
| Alizadeh, A; Khezri, MB; Shahamat, H; Yaghoobi, S | 1 |
| Bi, X; Lao, J; Li, Y; Liu, X; Tan, Y; Wang, Q; Zhang, N | 1 |
| Choudhury, A; Magoon, R | 1 |
| Carregaro, AB; de Carvalho, LL; Flaherty, D; Mattos-Junior, E; Nishimura, LT | 1 |
| Chen, P; Gartling, GJ; Kimball, EE; Powell, ME; Rousseau, B; Sayce, LJ | 1 |
| Guo, FQ; Li, ZS; Ma, JH; Wang, T; Wang, Z; Wei, JF; Zhang, WW; Zheng, LN | 1 |
| Azami, M; Kamali, A; Rad, MT; Shahtaheri, SY; Yazdi, B | 1 |
| Ouchi, K | 1 |
| Berjano, P; Chang, JM; Clavijo, CF; Daniels, AH; Deviren, V; Eastlack, RK; Glassman, SD; Hoh, DJ; Kanter, AS; Kim, HJ; Koski, T; Lenke, LG; Lewis, JM; McLawhorn, M; Mummaneni, PV; Mummaneni, VP; Mundis, GM; Nemergut, EC; Okonkwo, DO; Park, P; Sciubba, DM; Shaffrey, C; Shin, JH; Smith, JS; Than, KD; Turner, JD; Uribe, JS; Vinci, SB; Walker, CT; Wang, MY; Weller, MA | 1 |
| Bazybek, N; Ma, G; Wei, Y; Wen, K; Wu, Y | 1 |
| Connors, JR; Deep, NL; Huncke, TK; Roland, JT | 1 |
| Baek, SY; Han, W; Jeong, CY; Kim, JW; Kim, TW; Lee, DE; Park, DH; Park, SG; Ryu, KH | 1 |
| Doyle, DJ; Jain, A; Lamperti, M | 1 |
| Hu, S; Ju, X; Li, Q; Li, Y; Wang, S; Xu, S | 2 |
| Arroyo, L; Hanna, B; Hopkins, A; O'Sullivan, ML; Tisotti, T; Valverde, A | 1 |
| Alizargar, J; Etemadi Sh, M; Hsieh, NC; Jafarzadeh, K; Kaviani, N; Ranjbarian, P; Wu, SV | 1 |
| Horr, M; Lucera, TM; Mattos-Junior, E; Santana, IN; Santos, MA | 1 |
| Cao, YY; Ding, XD; Li, L; Zhao, GY | 1 |
| Brioschi, FA; Bronzo, V; Carotenuto, AM; Del Prete, G; Gioeni, D; Jacchetti, A; Lazzarini, E | 1 |
| Acquafredda, C; Centonze, P; Crovace, A; Di Bella, C; Fiorentino, M; Lacitignola, L; Stabile, M; Staffieri, F | 1 |
| Rekatsina, M; Staikou, C; Theodosopoulou, P | 2 |
| Injampa, S; Komonhirun, R; Kumdang, S; Pasutharnchat, K; Seangrung, R | 1 |
| Bao, D; Chi, D; Jin, X; Li, L; Liang, Y; Liu, B; Qiao, L; Wang, Y; Zhang, D; Zhang, Y | 1 |
| Muslih, AH; Sami, DS | 1 |
| Liu, Y; Zhang, H; Zhang, J; Zhao, L; Zhao, Z | 1 |
| Alnujaidi, OA; El Sanea, O; Elnabtity, AM; Hegab, A; Ibrahim, M | 1 |
| Ao, T; Guo, H; Kalika, P; Ran, R; Wang, J; Xiao, Y; Xue, R; Zhang, X; Zheng, J | 1 |
| Li, H; Li, P; Li, S; Wang, R | 1 |
| Moshari, A; Moshari, M; Vahedi, Z | 1 |
| Cai, X; Chen, C; Gao, R; Wang, R; Zhang, X | 1 |
| Bilgin, S; Dost, B; Kaya, C; Koksal, E; Ozbalci, GS; Turunc, E; Ustun, YB | 1 |
| Al Assadi, S; Kanazi, G; Karam, C; Zeeni, C | 1 |
| El-Hawari, SF; Itami, T; Koyama, Y; Oyama, N; Sano, T; Tamura, J; Yamashita, K | 1 |
| Cao, J; Tian, T; Xiao, YG; Xue, FS | 1 |
| Bengono Bengono, RS; Metogo, JM; Minkande, JZ; Ndikontar, R; Ngouatna, S; Ntock, FN; Tochie, JN | 1 |
| Billings, FT; Clifton, JC; Freundlich, RE; Hernandez, A; Jelly, CA; Schaffer, AJ; Shotwell, ME | 1 |
| Qin, P; Wei, K; Yang, Q; Zhang, H; Zheng, X; Zhu, Y | 1 |
| Atayee, RS; Chang, J; Edmonds, KP | 1 |
| Lv, X; Sun, P; Yin, D; Zhang, Y | 1 |
| Guo, K; Huang, J; Huang, Y; Jin, L; Liang, Y; Miao, P; Wang, C; Wang, H; Xu, L; Yu, Y | 1 |
| Lijovic, L; Pazur, I; Perisa, N; Radocaj, T; Skrtic, M | 1 |
| Chen, Q; Lai, Y; Li, G; Wei, K; Xiang, C | 1 |
8 review(s) available for dexmedetomidine and lidocaine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Systemic analgesia and co-analgesia.
Topics: Amines; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Dexmedetomidine; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Lidocaine; Narcotic Antagonists; Pain, Postoperative | 2006 |
Anesthesia for outpatient cosmetic surgery.
Topics: Algorithms; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia; Anesthetics, Local; Dexmedetomidine; Fentanyl; Fires; Humans; Lidocaine; Oxygen; Safety Management; Societies, Medical; Surgery, Plastic | 2008 |
Analgesia in the surgical intensive care unit.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; Clonidine; Critical Care; Cyclohexanecarboxylic Acids; Dexmedetomidine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydromorphone; Intensive Care Units; Ketamine; Lidocaine; Morphine; Pain; Pain Management; Pain Measurement; Pain, Postoperative; Physical Therapy Modalities | 2017 |
Postoperative Pain Control Following Craniotomy: A Systematic Review of Recent Clinical Literature.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Craniotomy; Dexmedetomidine; Humans; Lidocaine; Pain Management; Pain, Postoperative; Randomized Controlled Trials as Topic | 2017 |
Recent research and development of local anesthetic-loaded microspheres.
Topics: Anesthetics, Local; Animals; Bupivacaine; Delayed-Action Preparations; Dexmedetomidine; Drug Carriers; Drug Compounding; Drug Liberation; Emulsions; Humans; Hydrogels; Ibuprofen; Lactates; Lidocaine; Microfluidics; Microspheres; Polyesters; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Solvents; Temperature | 2020 |
Different interventions for preventing postoperative catheter-related bladder discomfort: a systematic review and meta-analysis.
Topics: Chlorpheniramine; Dexmedetomidine; Gabapentin; Haloperidol; Humans; Ketamine; Lidocaine; Meperidine; Nefopam; Pain, Postoperative; Pregabalin; Tolterodine Tartrate; Tramadol; Urinary Bladder; Urinary Catheters | 2022 |
Sufentanil, dexmedetomidine combined with surface anesthesia for awake fiberoptic nasotracheal intubation in the patient with severe mouth opening difficulty undergoing wedge resection of the right upper lung: A case report and literature review.
Topics: Anesthesia, General; Dexmedetomidine; Fiber Optic Technology; Humans; Intubation, Intratracheal; Lidocaine; Lung; Male; Middle Aged; Mouth; Sufentanil; Wakefulness | 2023 |
49 trial(s) available for dexmedetomidine and lidocaine
| Article | Year |
|---|---|
Adding dexmedetomidine to lidocaine for intravenous regional anesthesia.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Female; Forearm; Hand; Hemodynamics; Humans; Lidocaine; Male; Middle Aged; Monitoring, Intraoperative; Nerve Block; Orthopedic Procedures; Pain, Postoperative | 2004 |
Addition of dexmedetomidine to lidocaine for intravenous regional anaesthesia.
Topics: Adult; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Local; Blood Pressure; Dexmedetomidine; Double-Blind Method; Electrocardiography; Female; Fentanyl; Hand; Hemodynamics; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Pain Measurement; Pain, Postoperative; Prospective Studies | 2005 |
Premedication with dexmedetomidine alone or together with 0.5% lidocaine for IVRA.
Topics: Adult; Analgesia; Analgesics, Non-Narcotic; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Local; Carpal Tunnel Syndrome; Dexmedetomidine; Double-Blind Method; Female; Hemodynamics; Humans; Lidocaine; Male; Outpatients; Pain, Postoperative; Premedication; Young Adult | 2010 |
Cardiopulmonary and isoflurane-sparing effects of epidural or intravenous infusion of dexmedetomidine in cats undergoing surgery with epidural lidocaine.
Topics: Analgesics, Non-Narcotic; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Animals; Blood Gas Analysis; Cats; Dexmedetomidine; Female; Heart Rate; Hysterectomy; Infusions, Intravenous; Injections, Epidural; Isoflurane; Lidocaine; Ovariectomy; Respiratory Rate | 2010 |
Effects of fentanyl-lidocaine-propofol and dexmedetomidine-lidocaine-propofol on tracheal intubation without use of muscle relaxants.
Topics: Adult; Anesthetics, Intravenous; Blood Pressure; Dexmedetomidine; Drug Combinations; Female; Fentanyl; Heart Rate; Humans; Intubation, Intratracheal; Lidocaine; Male; Middle Aged; Propofol; Young Adult | 2010 |
Effect of dexmedetomidine, morphine-lidocaine-ketamine, and dexmedetomidine-morphine-lidocaine-ketamine constant rate infusions on the minimum alveolar concentration of isoflurane and bispectral index in dogs.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Local; Animals; Consciousness Monitors; Cross-Over Studies; Dexmedetomidine; Dogs; Drug Interactions; Drug Therapy, Combination; Female; Isoflurane; Ketamine; Lidocaine; Male; Morphine; Pulmonary Alveoli | 2013 |
Evaluation of the isoflurane-sparing effects of fentanyl, lidocaine, ketamine, dexmedetomidine, or the combination lidocaine-ketamine-dexmedetomidine during ovariohysterectomy in dogs.
Topics: Anesthesia, General; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Dexmedetomidine; Dogs; Female; Fentanyl; Hysterectomy; Isoflurane; Ketamine; Lidocaine; Ovariectomy | 2013 |
Preemptive dexmedetomidine to prevent propofol injection pain in children.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Child; Child, Preschool; Dexmedetomidine; Double-Blind Method; Elective Surgical Procedures; Female; Humans; Lidocaine; Male; Midazolam; Pain; Pain Measurement; Propofol | 2015 |
Postoperative analgesic effects of either a constant rate infusion of fentanyl, lidocaine, ketamine, dexmedetomidine, or the combination lidocaine-ketamine-dexmedetomidine after ovariohysterectomy in dogs.
Topics: Analgesia; Analgesics, Non-Narcotic; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Animals; Dexmedetomidine; Dogs; Drug Combinations; Female; Fentanyl; Hysterectomy; Ketamine; Lidocaine; Ovariectomy; Pain, Postoperative | 2015 |
Antinociceptive effects of three escalating dexmedetomidine and lignocaine constant rate infusions in conscious horses.
Topics: Analgesics; Animals; Chromatography, Liquid; Cross-Over Studies; Dexmedetomidine; Dose-Response Relationship, Drug; Electric Stimulation; Horses; Hypnotics and Sedatives; Infusions, Intravenous; Lidocaine; Male; Mass Spectrometry; Random Allocation; Reflex | 2014 |
A comparison among infusion of lidocaine and dexmedetomidine alone and in combination in subjects undergoing coronary artery bypass graft: a randomized trial.
Topics: Aged; Anesthetics, Local; Biomarkers; Coronary Artery Bypass, Off-Pump; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Postoperative Complications; Prospective Studies; Single-Blind Method; Troponin I | 2014 |
Effect of dexmedetomidine injected into the oral mucosa in combination with lidocaine on local anesthetic potency in humans: a crossover double-blind study.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-2 Receptor Agonists; Adult; Anesthetics, Local; Area Under Curve; Blood Pressure; Consciousness; Cross-Over Studies; Dexmedetomidine; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Heart Rate; Humans; Injections; Lidocaine; Male; Mouth Mucosa; Pain Threshold | 2015 |
"ANESTHETIC SPARING EFFECT OF INTRAOPERATIVE LIGNOCAINE OR DEXMEDETOMIDINE INFUSION ON SEVOFLURANE DURING GENERAL ANESTHESIA".
Topics: Abdomen; Administration, Intravenous; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, General; Dexmedetomidine; Double-Blind Method; Female; Humans; Lidocaine; Male; Methyl Ethers; Middle Aged; Propofol; Prospective Studies; Sevoflurane; Young Adult | 2015 |
Perineural Dexmedetomidine as an Adjuvant Reduces the Median Effective Concentration of Lidocaine for Obturator Nerve Blocking: A Double-Blinded Randomized Controlled Trial.
Topics: Adjuvants, Pharmaceutic; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anesthetics, Local; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Lidocaine; Male; Middle Aged; Muscle Strength; Muscle, Skeletal; Nerve Block; Obturator Nerve; Young Adult | 2016 |
The effect of dexmedetomidine pretreatment on the median effective bolus dose of propofol for facilitating laryngeal mask airway insertion.
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Apnea; Dexmedetomidine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Laryngeal Masks; Lidocaine; Male; Middle Aged; Propofol | 2017 |
Dexmedetomidine Added to Local Anesthetic Mixture of Lidocaine and Ropivacaine Enhances Onset and Prolongs Duration of a Popliteal Approach to Sciatic Nerve Blockade.
Topics: Adult; Aged; Aged, 80 and over; Amides; Anesthetics, Local; Animals; Dexmedetomidine; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Ropivacaine; Sciatic Nerve | 2017 |
Effects of intravenous lidocaine, dexmedetomidine and their combination on postoperative pain and bowel function recovery after abdominal hysterectomy.
Topics: Abdomen; Adult; Aged; Analgesics, Non-Narcotic; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hysterectomy; Infusions, Intravenous; Intestines; Lidocaine; Middle Aged; Pain, Postoperative; Prospective Studies; Recovery of Function | 2017 |
Comparison of intratesticular lidocaine, sacrococcygeal epidural lidocaine and intravenous methadone in cats undergoing castration: a prospective, randomized, investigator-blind clinical trial.
Topics: Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local; Animals; Cats; Dexmedetomidine; Fentanyl; Lidocaine; Male; Methadone; Orchiectomy; Pain, Postoperative; Pregnanediones; Prospective Studies; Sacrococcygeal Region; Testis | 2017 |
The impact of dexmedetomidine or xylocaine continuous infusion on opioid consumption and recovery after laparoscopic sleeve gastrectomy.
Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Female; Gastrectomy; Humans; Infusions, Intravenous; Laparoscopy; Lidocaine; Male; Obesity, Morbid; Prospective Studies | 2017 |
A randomized double-blind controlled trial comparing three sedation regimens during flexible bronchoscopy: Dexmedetomidine, alfentanil and lidocaine.
Topics: Adolescent; Adult; Aged; Alfentanil; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bronchoscopy; Conscious Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Lidocaine; Male; Middle Aged; Pain; Pain Measurement; Retrospective Studies; Young Adult | 2018 |
Comparison of effect of dexmedetomidine and lidocaine on intracranial and systemic hemodynamic response to chest physiotherapy and tracheal suctioning in patients with severe traumatic brain injury.
Topics: Adolescent; Adult; Brain Injuries, Traumatic; Dexmedetomidine; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Intracranial Pressure; Lidocaine; Male; Middle Aged; Physical Therapy Modalities; Prospective Studies; Respiration, Artificial; Suction; Young Adult | 2018 |
Influence of dexmedetomidine and lidocaine on perioperative opioid consumption in laparoscopic intestine resection: a randomized controlled clinical trial.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Female; Humans; Intestinal Neoplasms; Laparoscopy; Lidocaine; Male; Middle Aged; Opioid-Related Disorders; Pain Measurement; Pain, Postoperative; Perioperative Care; Prognosis | 2018 |
Sedation with dexmedetomidine prolongs the analgesic duration of brachial plexus block: a randomised controlled trial.
Topics: Adult; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Local; Brachial Plexus Block; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Lidocaine; Male; Midazolam; Middle Aged; Orthopedic Procedures; Ropivacaine; Time Factors; Upper Extremity | 2019 |
[Comparison between Dexmedetomidine and Fentanyl Infusion during Fetoscopic Laser Photocoagulation for Twin to Twin Transfusion Syndrome].
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Dexmedetomidine; Female; Fentanyl; Fetofetal Transfusion; Humans; Lidocaine; Light Coagulation; Pain; Pain Management; Pregnancy; Prospective Studies | 2017 |
Haemodynamic changes and incisional bleeding after scalp infiltration of dexmedetomidine with lidocaine in neurosurgical patients.
Topics: Adult; Aged; Anesthetics, Local; Blood Loss, Surgical; Blood Pressure; Dexmedetomidine; Drug Therapy, Combination; Ephedrine; Epinephrine; Heart Rate; Hemifacial Spasm; Hemodynamic Monitoring; Hemodynamics; Humans; Hypotension; Lidocaine; Microvascular Decompression Surgery; Middle Aged; Prospective Studies; Scalp; Vasoconstrictor Agents; Young Adult | 2019 |
Sedative effect of dexmedetomidine in spinal-epidural anesthesia on hysteromyomectomy.
Topics: Administration, Intravenous; Adult; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Consciousness; Dexmedetomidine; Female; Heart Rate; Humans; Hypnotics and Sedatives; Injections, Spinal; Lidocaine; Middle Aged; Propofol; Ropivacaine; Time Factors; Uterine Myomectomy | 2018 |
Comparison of intravenous lidocaine and dexmedetomidine infusion for prevention of postoperative catheter-related bladder discomfort: a randomized controlled trial.
Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Female; Humans; Hysterectomy; Infusions, Intravenous; Lidocaine; Middle Aged; Pain, Postoperative; Prospective Studies; Tramadol; Urinary Catheterization; Urinary Catheters | 2019 |
Effects of intravenous infusion of lidocaine and dexmedetomidine on inhibiting cough during the tracheal extubation period after thyroid surgery.
Topics: Adult; Airway Extubation; Anesthesia Recovery Period; Anesthetics, Local; Cough; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Pain Measurement; Pilot Projects; Prospective Studies; Thyroid Gland | 2019 |
Clinical effects of epidurally administered dexmedetomidine with or without lidocaine in sheep.
Topics: Anesthetics, Local; Animals; Blood Pressure; Dexmedetomidine; Drug Combinations; Female; Heart Rate; Hypnotics and Sedatives; Injections, Epidural; Lidocaine; Male; Pain; Respiratory Rate; Sheep | 2020 |
Clinical Comparison of Adding Sulfate Magnesium and Dexmedetomidine in Axillary Plexus Block for Prolonging the Duration of Sensory and Motor Block: Study Protocol for a Double-blind Randomized Clinical Trial.
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics; Anesthetics, Local; Brachial Plexus Block; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Forearm Injuries; Hand Injuries; Humans; Lidocaine; Magnesium Sulfate; Male; Middle Aged; Pain, Postoperative; Pain, Procedural; Time Factors; Young Adult | 2020 |
Dexmedetomidine 2 ppm Is Appropriate for the Enhancement Effect of Local Anesthetic Action of Lidocaine in Inferior Alveolar Nerve Block: A Preliminary, Randomized Cross-over Study.
Topics: Anesthesia, Local; Anesthetics, Local; Cross-Over Studies; Dexmedetomidine; Humans; Lidocaine; Mandibular Nerve | 2020 |
Effects of intravenous lidocaine, dexmedetomidine, and their combination on IL-1, IL-6 and TNF-α in patients undergoing laparoscopic hysterectomy: a prospective, randomized controlled trial.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Hysterectomy; Inflammation; Infusions, Intravenous; Interleukin-1; Interleukin-6; Laparoscopy; Lidocaine; Middle Aged; Pain, Postoperative; Postoperative Nausea and Vomiting; Prospective Studies; Tumor Necrosis Factor-alpha | 2021 |
Use of intravenous lidocaine to treat dexmedetomidine-induced bradycardia in sedated and anesthetized dogs.
Topics: Anesthetics, Inhalation; Animals; Bradycardia; Dexmedetomidine; Dog Diseases; Dogs; Female; Heart Rate; Infusions, Intravenous; Isoflurane; Lidocaine; Prospective Studies | 2021 |
Effects of lidocaine, dexmedetomidine, and their combination infusion on postoperative nausea and vomiting following laparoscopic hysterectomy: a randomized controlled trial.
Topics: Adult; Anesthesia, General; Bradycardia; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Fentanyl; Humans; Hysterectomy; Incidence; Laparoscopy; Lidocaine; Middle Aged; Pain, Postoperative; Postoperative Nausea and Vomiting; Remifentanil | 2021 |
Clinical effects of preemptive intra-articular lidocaine, dexmedetomidine and lidocaine-dexmedetomidine administration in dogs undergoing arthroscopy.
Topics: Animals; Arthroscopy; Dexmedetomidine; Dog Diseases; Dogs; Lidocaine; Pain, Postoperative; Prospective Studies | 2021 |
Effects of Intravenous Dexmedetomidine Versus Lidocaine on Postoperative Pain, Analgesic Consumption and Functional Recovery After Abdominal Gynecological Surgery: A Randomized Placebo-controlled Double Blind Study.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; Infusions, Intravenous; Lidocaine; Middle Aged; Pain, Postoperative; Sleep Quality | 2021 |
Comparison of the hemodynamic response of dexmedetomidine versus additional intravenous lidocaine with propofol during tracheal intubation: a randomized controlled study.
Topics: Administration, Intravenous; Adult; Anesthesia, General; Blood Pressure; Dexmedetomidine; Elective Surgical Procedures; Female; Heart Rate; Humans; Intubation, Intratracheal; Laryngoscopy; Lidocaine; Male; Middle Aged; Propofol; Prospective Studies | 2021 |
Dexmedetomidine vs. lidocaine for postoperative analgesia in pediatric patients undergoing craniotomy: a protocol for a prospective, randomized, double-blinded, placebo-controlled trial.
Topics: Adult; Analgesia; Analgesics, Non-Narcotic; Child; Child, Preschool; Craniotomy; Dexmedetomidine; Double-Blind Method; Humans; Infant; Lidocaine; Pain, Postoperative; Prospective Studies; Randomized Controlled Trials as Topic | 2021 |
A COMPARATIVE STUDY OF TWO DIFFERENT DOSES OF DEXMEDETOMIDINE AS ADJUNCT TO LIDOCAINE IN INTRAVENOUS REGIONAL ANESTHESIA.
Topics: Anesthesia, Conduction; Anesthetics, Local; Dexmedetomidine; Hand; Humans; Lidocaine; Pain Measurement; Pain, Postoperative | 2021 |
Effect and Mechanism of Lidocaine Pretreatment Combined with Dexmedetomidine on Oxidative Stress in Patients with Intracranial Aneurysm Clipping.
Topics: Animals; Dexmedetomidine; Hemodynamics; Humans; Intracranial Aneurysm; Lidocaine; Oxidative Stress; Rats | 2021 |
Combined opioid free and loco-regional anaesthesia enhances the quality of recovery in sleeve gastrectomy done under ERAS protocol: a randomized controlled trial.
Topics: Adult; Anesthesia, Conduction; Anesthesia, Local; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Local; Atracurium; Dexmedetomidine; Enhanced Recovery After Surgery; Female; Fentanyl; Gastrectomy; Humans; Hypnotics and Sedatives; Ketamine; Lidocaine; Male; Nerve Block; Neuromuscular Blocking Agents; Pain Management; Pain, Postoperative; Propofol; Young Adult | 2022 |
Clinical Efficacy of Perioperative Intravenous Dexmedetomidine and Lidocaine Combined Infusion for Thyroidectomy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Humans; Infusions, Intravenous; Lidocaine; Pain, Postoperative; Postoperative Nausea and Vomiting; Propofol; Prospective Studies; Thyroidectomy; Treatment Outcome | 2022 |
Efficacy of adding dexmedetomidine to lidocaine to enhance inferior alveolar nerve block in patients with asymptomatic irreversible pulpitis: double-blind randomized clinical trial.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Nerve Block; Pain; Pulpitis | 2022 |
Comparison of Ketamine, Dexmedetomidine and Lidocaine in Multimodal Analgesia Management Following Sleeve Gastrectomy Surgery: A Randomized Double-Blind Trial.
Topics: Analgesia; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Gastrectomy; Humans; Ketamine; Lidocaine; Pain, Postoperative; Prospective Studies | 2022 |
The efficacy and safety of an adapted opioid-free anesthesia regimen versus conventional general anesthesia in gynecological surgery for low-resource settings: a randomized pilot study.
Topics: Analgesics, Opioid; Anesthesia, General; Clonidine; Dexamethasone; Dexmedetomidine; Diazepam; Female; Fentanyl; Gynecologic Surgical Procedures; Humans; Isoflurane; Ketamine; Lidocaine; Magnesium Sulfate; Pain, Postoperative; Pilot Projects; Propofol; Rocuronium; Saline Solution | 2022 |
Effect of lidocaine or dexmedetomidine on postoperative recovery in elder patients undergoing colorectal surgery.
Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Colorectal Surgery; Dexmedetomidine; Double-Blind Method; Flatulence; Humans; Infusions, Intravenous; Lidocaine; Pain, Postoperative; Postoperative Complications | 2023 |
Evaluation of the Effect of New Multimodal Analgesia Regimen for Cardiac Surgery: A Prospective, Randomized Controlled, Single-Center Clinical Study.
Topics: Acetaminophen; Analgesia; Cardiac Surgical Procedures; Chronic Pain; Dexmedetomidine; Gabapentin; Humans; Ketamine; Lidocaine; Prospective Studies; Sufentanil | 2023 |
Hemodynamic Safety and Effect of Dexmedetomidine on Superficial Cervical Block Quality for Carotid Endarterectomy: A Prospective Study.
Topics: Anesthetics, Local; Dexmedetomidine; Endarterectomy, Carotid; Hemodynamics; Humans; Levobupivacaine; Lidocaine; Prospective Studies | 2023 |
Comparison of the Effects of Dexmedetomidine and Lidocaine on Stress Response and Postoperative Delirium of Older Patients Undergoing Thoracoscopic Surgery: A Randomized Controlled Trial.
Topics: Dexmedetomidine; Emergence Delirium; Humans; Hydrocortisone; Interleukin-6; Lidocaine; Thoracic Surgery; Tumor Necrosis Factor-alpha | 2023 |
54 other study(ies) available for dexmedetomidine and lidocaine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
The prevention of pain from injection of propofol by dexmedetomidine and comparison with lidocaine.
Topics: Dexmedetomidine; Humans; Injections, Intravenous; Lidocaine; Pain; Propofol | 2005 |
Effects of alpha2-adrenoceptor agonists on tetrodotoxin-resistant Na+ channels in rat dorsal root ganglion neurons.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Algorithms; Anesthetics, Local; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Resistance; Ganglia, Spinal; Lidocaine; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Yohimbine | 2007 |
The efficacy and neurotoxicity of dexmedetomidine administered via the epidural route.
Topics: Adrenergic alpha-Agonists; Anesthesia, Epidural; Anesthetics, Local; Animals; Blood Gas Analysis; Blood Pressure; Dexmedetomidine; Heart Rate; Injections, Epidural; Lidocaine; Motor Activity; Myelin Sheath; Pain; Pain Measurement; Rabbits; Random Allocation; Treatment Outcome | 2008 |
[Use of high-dose dexmedetomidine infusion for anesthesia and sedation in a patient for microlaryngeal surgery maintained with spontaneous breathing].
Topics: Aged; Anesthesia, Intravenous; Anesthesia, Local; Conscious Sedation; Dexmedetomidine; Ephedrine; Fentanyl; Humans; Hypotension; Intraoperative Care; Intraoperative Complications; Larynx; Lidocaine; Male; Microsurgery; Respiration; Respiratory Physiological Phenomena | 2008 |
Dexmedetomidine enhances the local anesthetic action of lidocaine via an alpha-2A adrenoceptor.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Lidocaine; Male; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha-2; Yohimbine | 2008 |
The combined neuroprotective effects of lidocaine and dexmedetomidine after transient forebrain ischemia in rats.
Topics: Anesthetics, Local; Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Brain Chemistry; Cerebrovascular Circulation; Dexmedetomidine; Drug Combinations; Glutamic Acid; Heart Rate; Hippocampus; Hypnotics and Sedatives; Ischemic Attack, Transient; Lidocaine; Male; Microdialysis; Neuroprotective Agents; Neurotransmitter Agents; Norepinephrine; Prosencephalon; Rats; Rats, Sprague-Dawley | 2009 |
Dexmedetomidine and clonidine inhibit the function of Na(v)1.7 independent of α(2)-adrenoceptor in adrenal chromaffin cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding Sites; Cattle; Cells, Cultured; Chromaffin Cells; Clonidine; Cyclopentanes; Dexmedetomidine; Imidazoles; Lidocaine; Organophosphorus Compounds; Ouabain; Pain; Receptors, Adrenergic, alpha-2; Scorpion Venoms; Sodium; Sodium Channels; Tetrodotoxin; Veratridine; Yohimbine | 2011 |
An anesthetic protocol for adult heartworms removal in two cases of canine caval syndrome.
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Anti-Arrhythmia Agents; Bupivacaine; Butorphanol; Clinical Protocols; Dexmedetomidine; Dirofilariasis; Dog Diseases; Dogs; Heart Murmurs; Hypnotics and Sedatives; Lidocaine; Male; Methyl Ethers; Respiratory Insufficiency; Sevoflurane | 2014 |
Dexmedetomidine dose-dependently enhances local anesthetic action of lidocaine.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-2 Receptor Agonists; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Injections, Epidural; Lidocaine; Male; Rats; Rats, Sprague-Dawley | 2014 |
Effects of lidocaine, dexmedetomidine or their combination on the minimum alveolar concentration of sevoflurane in dogs.
Topics: Analysis of Variance; Anesthetics, Combined; Animals; Dexmedetomidine; Dogs; Dose-Response Relationship, Drug; Infusions, Intravenous; Lidocaine; Methyl Ethers; Sevoflurane | 2014 |
Lidocaine, dexmedetomidine and their combination reduce isoflurane minimum alveolar concentration in dogs.
Topics: Anesthesia, Inhalation; Anesthetics, Combined; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Dexmedetomidine; Dogs; Drug Combinations; Female; Heart Rate; Isoflurane; Lidocaine; Male; Pulmonary Alveoli; Random Allocation | 2014 |
Dexmedetomidine augments the effect of lidocaine: power spectrum and nerve conduction velocity distribution study.
Topics: Action Potentials; Anesthetics, Local; Animals; Dexmedetomidine; Drug Synergism; Fourier Analysis; Lidocaine; Neural Conduction; Rats; Sciatic Nerve | 2015 |
Dexmedetomidine (12.5 μg/mL) improves tissue distribution, anesthetic action, and hemodynamic effects of lidocaine after palatal infiltration in rats.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Hemodynamics; Lidocaine; Male; Palate; Rats; Rats, Wistar; Tissue Distribution | 2016 |
Monitored Anesthesia Care Versus General Anesthesia: Experience With the Medtronic CoreValve.
Topics: Aged; Aged, 80 and over; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Case-Control Studies; Dexmedetomidine; Echocardiography; Etomidate; Female; Fentanyl; Humans; Length of Stay; Lidocaine; Male; Methyl Ethers; Monitoring, Intraoperative; Retrospective Studies; Risk Assessment; Sevoflurane; Transcatheter Aortic Valve Replacement; Treatment Outcome | 2016 |
A clinical study to determine the efficacy of 7ppm dexmedetomidine as an adjuvant to 2% lignocaine in infraorbital nerve block.
Topics: Anesthetics, Local; Dexmedetomidine; Humans; Lidocaine; Nerve Block | 2016 |
Effect of dexmedetomidine priming on convulsion reaction induced by lidocaine.
Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Animals; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Lidocaine; Male; Rabbits; Seizures | 2016 |
Awake Laryngoscopy in the Emergency Department.
Topics: Administration, Topical; Aged; Airway Management; Analgesics; Anesthesia; Consciousness; Contraindications; Dexmedetomidine; Emergency Service, Hospital; Female; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Ketamine; Laryngoscopy; Lidocaine; Midazolam; Middle Aged | 2017 |
The influence of demeanor on scores from two validated feline pain assessment scales during the perioperative period.
Topics: Anesthesia; Animals; Cats; Dexmedetomidine; Hydromorphone; Imidazoles; Ketamine; Lidocaine; Male; Meloxicam; Orchiectomy; Pain Measurement; Pain, Postoperative; Perioperative Period; Prospective Studies; Thiazines; Thiazoles | 2017 |
The safety and efficacy of dexmedetomidine-remifentanil in children undergoing flexible bronchoscopy: A retrospective dose-finding trial.
Topics: Anesthesia Recovery Period; Bronchoscopy; Child; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Lidocaine; Male; Midazolam; Movement; Piperidines; Remifentanil; Retrospective Studies | 2017 |
Dexmedetomidine's inhibitory effects on acetylcholine release from cholinergic nerves in guinea pig trachea: a mechanism that accounts for its clinical benefit during airway irritation.
Topics: Acetylcholine; Anesthetics; Animals; Cholinergic Neurons; Dexmedetomidine; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Lidocaine; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Remifentanil; Trachea | 2017 |
Pharmacological advances in the multimodal management of perioperative analgesia.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Clinical Trials as Topic; Combined Modality Therapy; Dexmedetomidine; Drug Therapy, Combination; Humans; Ibuprofen; Ketamine; Lidocaine; Magnesium; Ondansetron; Pain Management; Pain, Postoperative; Pregabalin | 2017 |
Dexmedetomidine Protects PC12 Cells from Lidocaine-Induced Cytotoxicity Through Downregulation of COL3A1 Mediated by miR-let-7b.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Caspase 3; Cell Movement; Cell Proliferation; Collagen Type III; Computational Biology; Dexmedetomidine; Gene Expression Regulation; Genes, Reporter; Lidocaine; Luciferases; MicroRNAs; Neuroprotective Agents; Oligoribonucleotides; PC12 Cells; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Rats; RNA, Small Interfering; Signal Transduction; Voltage-Gated Sodium Channel Blockers | 2017 |
Dexmedetomidine inhibits activation of the MAPK pathway and protects PC12 and NG108-15 cells from lidocaine-induced cytotoxicity at its maximum safe dose.
Topics: Animals; Apoptosis; Cell Survival; Dexmedetomidine; Dose-Response Relationship, Drug; Lidocaine; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neuroprotective Agents; PC12 Cells; Rats | 2017 |
Cardiorespiratory effects of epidural anesthesia using lidocaine with morphine or dexmedetomidine in capuchin monkeys (Sapajus sp.) undergoing bilateral tubal ligation surgery, anesthetized with isoflurane.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Inhalation; Anesthetics, Local; Animals; Blood Pressure; Body Temperature; Cebinae; Dexmedetomidine; Female; Heart Rate; Isoflurane; Lidocaine; Lumbosacral Region; Morphine; Random Allocation; Sterilization, Tubal | 2017 |
Addition of dexmedetomidine to QX-314 enhances the onset and duration of sciatic nerve block in rats.
Topics: Action Potentials; Animals; Dexmedetomidine; Hot Temperature; Lidocaine; Male; Nerve Block; Nociception; Ranidae; Rats, Sprague-Dawley; Sciatic Nerve; Time Factors | 2018 |
Comparison of sedation regimens during flexible bronchoscopy.
Topics: Alfentanil; Anesthetics, Intravenous; Anesthetics, Local; Bronchoscopy; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Lidocaine; Randomized Controlled Trials as Topic | 2018 |
Tactics for reducing opioids consumption for bariatric surgery.
Topics: Analgesics, Opioid; Bariatric Surgery; Dexmedetomidine; Gastrectomy; Laparoscopy; Lidocaine | 2017 |
A Combination of Dexmedetomidine and Lidocaine Is a Cardiovascularly Safe Dental Local Anesthetic for Hypertensive Rats Treated With a Nonselective β-Adrenergic Antagonist.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Animals; Blood Pressure; Bradycardia; Dexmedetomidine; Drug Therapy, Combination; Epinephrine; Heart Rate; Humans; Hypertension; Lidocaine; Propranolol; Rats; Rats, Inbred SHR | 2017 |
Dexmedetomidine Increases the Latency of Thermal Antinociception in Rats.
Topics: Acute Pain; Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Animals; Dexmedetomidine; Disease Models, Animal; Drug Therapy, Combination; Epinephrine; Injections; Lidocaine; Male; Rats; Rats, Wistar; Time Factors | 2017 |
Dexmedetomidine as an Additive to Local Anesthesia: A Step to Development in Dentistry.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Analgesics, Non-Narcotic; Anesthesia, Local; Anesthetics, Local; Bicuspid; Child; Cross-Over Studies; Dexmedetomidine; Double-Blind Method; Epinephrine; Female; Humans; Lidocaine; Male; Nerve Block; Pain Measurement; Pain, Postoperative; Tooth Extraction; Treatment Outcome; Vital Signs | 2018 |
The Effect of Dexmedetomidine on Oral Mucosal Blood Flow and the Absorption of Lidocaine.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Animals; Blood Loss, Surgical; Dexmedetomidine; Lidocaine; Male; Mouth Mucosa; Oral Mucosal Absorption; Rabbits; Regional Blood Flow; Vasoconstrictor Agents; Vasodilator Agents | 2018 |
Dexmedetomidine ameliorates lidocaine-induced spinal neurotoxicity via inhibiting glutamate release and the PKC pathway.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Injections, Spinal; Lidocaine; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord | 2018 |
Comparing Postoperative Analgesic Effect of Dexmedetomidine or Dexamethasone Added to Lidocaine Through Infraclavicular Block in Forearm Surgery.
Topics: Adult; Analgesics; Anesthetics, Local; Brachial Plexus Block; Dexamethasone; Dexmedetomidine; Double-Blind Method; Female; Forearm; Fractures, Bone; Humans; Lidocaine; Male; Middle Aged; Orthopedic Procedures; Pain, Postoperative; Treatment Outcome; Young Adult | 2019 |
Dexmedetomidine protects PC12 cells from lidocaine-induced cytotoxicity via downregulation of Stathmin 1.
Topics: Animals; Apoptosis; Cell Cycle; Cell Proliferation; Dexmedetomidine; Down-Regulation; Lidocaine; PC12 Cells; Protective Agents; Rats; Stathmin | 2019 |
Opioid free anesthesia: is it too early to bid adieu?
Topics: Analgesics, Opioid; Anesthesia, Intravenous; Cholecystectomy, Laparoscopic; Dexmedetomidine; Lidocaine; Propofol; Prospective Studies | 2019 |
Continuous Rate Infusion of Ketamine Hydrochloride and Dexmedetomidine for Maintenance of Anesthesia during Laryngotracheal Surgery in New Zealand White Rabbits (
Topics: Analgesia; Anesthesia; Animals; Dexmedetomidine; Drug Administration Schedule; Drug Therapy, Combination; Female; Hypnotics and Sedatives; Ketamine; Lidocaine; Maintenance; Male; Rabbits | 2020 |
Dexmedetomidine protects against lidocaine-induced neurotoxicity through SIRT1 downregulation-mediated activation of FOXO3a.
Topics: Acetylation; Anesthetics, Local; Animals; Apoptosis; Cell Survival; Dexmedetomidine; Down-Regulation; Forkhead Box Protein O3; Lidocaine; Mice; Mice, Inbred C57BL; Neuroprotective Agents; PC12 Cells; Rats; RNA, Small Interfering; Sirtuin 1 | 2020 |
Neuroanesthesia Guidelines for Optimizing Transcranial Motor Evoked Potential Neuromonitoring During Deformity and Complex Spinal Surgery: A Delphi Consensus Study.
Topics: Anesthesia, General; Anesthetics, Intravenous; Consensus; Delphi Technique; Dexmedetomidine; Evoked Potentials, Motor; Humans; Intraoperative Neurophysiological Monitoring; Ketamine; Lidocaine; Neurosurgical Procedures; Practice Guidelines as Topic; Propofol; Spinal Cord; Spinal Curvatures | 2020 |
Adding Dexmedetomidine to Articaine Increases the Latency of Thermal Antinociception in Rats.
Topics: Anesthesia, Dental; Anesthetics, Local; Animals; Carticaine; Dexmedetomidine; Double-Blind Method; Epinephrine; Lidocaine; Male; Rats; Rats, Wistar | 2020 |
Cochlear Implantation Under Local Anesthesia With Conscious Sedation in the Elderly: First 100 Cases.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthesia, General; Anesthesia, Local; Cochlear Implantation; Conscious Sedation; Cost-Benefit Analysis; Dexmedetomidine; Feasibility Studies; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Injections, Subcutaneous; Lidocaine; Male; Postoperative Complications; Retrospective Studies; Treatment Outcome | 2021 |
Opioid-free anesthesia with a mixture of dexmedetomidine, ketamine, and lidocaine in one syringe for surgery in obese patients.
Topics: Analgesics, Opioid; Anesthesia; Cesarean Section; Dexmedetomidine; Double-Blind Method; Female; Humans; Ketamine; Lidocaine; Male; Obesity; Pain, Postoperative; Pregnancy; Syringes | 2020 |
Dexmedetomidine: another arrow in the quiver to fight COVID-19 in intensive care units.
Topics: COVID-19; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Lidocaine; SARS-CoV-2 | 2021 |
Injection of Lidocaine Alone versus Lidocaine plus Dexmedetomidine in Impacted Third Molar Extraction Surgery, a Double-Blind Randomized Control Trial for Postoperative Pain Evaluation.
Topics: Adolescent; Adult; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Injections; Lidocaine; Male; Molar, Third; Pain Management; Pain, Postoperative; Tooth Extraction; Young Adult | 2021 |
Comparative study on epidural administration of dexmedetomidine, dexmedetomidine-lidocaine or lidocaine in conscious rabbits.
Topics: Animals; Blood Gas Analysis; Dexmedetomidine; Lidocaine; Male; Rabbits | 2021 |
Dexmedetomidine Reduces the Lidocaine-Induced Neurotoxicity by Inhibiting Inflammasome Activation and Reducing Pyroptosis in Rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Dexmedetomidine; Inflammasomes; Lidocaine; Male; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Phosphorylation; Protein Kinase C-delta; Pyroptosis; Rats, Sprague-Dawley; Spinal Cord | 2021 |
Clinical efficacy of dexmedetomidine combined with lidocaine for femoral and sciatic nerve blocks in dogs undergoing stifle surgery.
Topics: Anesthetics, Local; Animals; Dexmedetomidine; Dog Diseases; Dogs; Femoral Nerve; Lidocaine; Nerve Block; Pain, Postoperative; Prospective Studies; Sciatic Nerve; Stifle; Treatment Outcome | 2021 |
Dexmedetomidine and Lidocaine: Useful Adjuvants for Analgesia after Abdominal Surgery?
Topics: Analgesia; Anesthetics, Local; Dexmedetomidine; Humans; Lidocaine; Pain Management | 2022 |
In Response to "Dexmedetomidine and Lidocaine: Useful Adjuvants for Analgesia after Abdominal Surgery?"
Topics: Analgesia; Anesthetics, Local; Dexmedetomidine; Humans; Lidocaine; Pain Management | 2022 |
A sequential allocation study to determine the ED
Topics: Anesthesia, Conduction; Anesthetics, Local; Clonidine; Dexmedetomidine; Double-Blind Method; Humans; Lidocaine; Pain | 2022 |
Sparing effect of tramadol, lidocaine, dexmedetomidine and their combination on the minimum alveolar concentration of sevoflurane in dogs.
Topics: Anesthetics, Inhalation; Animals; Dexmedetomidine; Dogs; Lidocaine; Methyl Ethers; Pulmonary Alveoli; Sevoflurane; Tramadol | 2022 |
Comparing Postoperative Analgesic Efficacy of Adding Ketamine, Dexmedetomidine and Lidocaine to Multimodal Regimen.
Topics: Analgesics; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Humans; Ketamine; Lidocaine; Pain, Postoperative | 2022 |
The Association Between Enhanced Recovery After Cardiac Surgery-Guided Analgesics and Postoperative Delirium.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; Dexmedetomidine; Emergence Delirium; Gabapentin; Humans; Ketamine; Lidocaine; Pain, Postoperative | 2023 |
A National Survey of Institutional Guidelines for the Use of Ketamine, Lidocaine, and Dexmedetomidine for Refractory Pain.
Topics: Analgesics, Opioid; Dexmedetomidine; Double-Blind Method; Humans; Ketamine; Lidocaine; Pain, Intractable | 2023 |