Page last updated: 2024-08-24

dexmedetomidine and isoflurane

dexmedetomidine has been researched along with isoflurane in 158 studies

Research

Studies (158)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (1.27)18.2507
2000's26 (16.46)29.6817
2010's97 (61.39)24.3611
2020's33 (20.89)2.80

Authors

AuthorsStudies
Amin, D; Jones, RM; Khan, ZP; Mant, TG; Munday, IT; Thornton, C1
Doré, CJ; Jones, RM; Lucas, MA; Newton, DE; Thornton, C1
Davies, FM; Guo, TZ; Kingery, WS; Limbird, L; Maze, M1
Bettschart-Wolfensberger, R; Kästner, SB; Keller, K; Von Rechenberg, B1
Kuusela, E; Mykkänen, K; Raekallio, M; Ropponen, H; Vainio, O; Väisänen, M1
Akens, MK; Bettschart-Wolfensberger, R; Boller, M; Kastner, SB; Kutter, A1
Hietanen, H; Huttula, J; Kuusela, E; Raekallio, M; Vainio, O1
Huju, V; Huttunen, P; Kuusela, E; Leppäluoto, J; Raekallio, M; Short, CE; Ström, S; Vainio, O; Valtonen, A1
Ibancovichi, JA; Martínez Taboada, F; Rioja, E; Santos, M; Tendillo, FJ1
Granholm, M; Kuusela, E; McKusick, B; Pascoe, PJ; Raekallio, M1
Ananda, RC; Feld, JM; Hoffman, IW; Hoffman, WE; Stechert, MM1
Aguilera, E; Benítez, A; Domínguez, JM; Gómez-Villamandos, RJ; Granados, MM; López, I; Palacios, C; Ruiz, I; Santisteban, JM1
Feld, J; Hoffman, WE1
Ananda, RC; Feld, J; Hoffman, WE; Paisansathan, C; Park, H1
Hung, CT; Lee, YY; Wong, SM1
Deutsch, E; Tobias, JD1
Campagnol, D; Ferreira, TH; Giordano, T; Monteiro, ER; Teixeira Neto, FJ1
Aspegrén, J; Hellebrekers, LJ; Lin, GY; McKusick, BC; Murrell, JC; Robben, JH1
Hellebrekers, LJ; McKusick, BC; Murrell, JC; Uilenreef, JJ1
Shields, JA1
Gerancher, JC; Nagle, PC1
Fornal, CA; Herrera, S; Jacobs, BL; Tung, A1
Bala, E; Dalton, JE; Farag, E; McLain, R; Nair, DR; Sessler, DI1
Camarini, ET; Coelho, L; de Moraes, M; Farah, GJ; Filho, LI; Pavan, AJ; Previdelli, IT1
Kobayashi, K; Nakazato, K; Sakamoto, A; Takemori, K; Yoshida, Y1
Fidalgo, A; Halder, S; Hossain, M; Januszewski, A; Ma, D; Maze, M; Sanders, RD; Shu, Y; Sun, P; Xu, J1
Richa, F; Yazigi, A1
Aal-Shaya, WA; Al-Faridi, K; Halawani, MM; Taha, WS; Tawfeeq, NA1
Li, M; Ma, D; Maze, M; Patel, S; Sanders, RD; Sun, P1
Abdelfattach, H; Abdelhamid, D; Elhakim, M; Elsayed, A; Elshafei, M; Magdy, H1
Cortopassi, SR; De Biaggi, CP; Dias, RA; Intelisano, TR; Moura, CA; Selmi, AL; Souza, SS1
Duchateau, L; Gasthuys, F; Marcilla, MG; Schauvliege, S1
Bottum, KM; Karmarkar, SW; Tischkau, SA1
Escobar, A; Ilkiw, JE; Pypendop, BH; Siao, KT; Stanley, SD2
Barter, LS; Ilkiw, JE; Pypendop, BH; Stanley, SD1
Duchateau, L; Gasthuys, F; Marcilla, MG; Schauvliege, S; Segaert, S1
Martin, DD; McKusick, BC; McSweeney, PM; Ramsey, DS1
Haga, HA; Lervik, A; Ranheim, B; Spadavecchia, C1
Chan, WS; Fan, SZ; Ko, WJ; Lin, TY; Sun, WZ; Tsai, JC; Yeh, YC1
Ibancovichi, JA; Millán, I; Santos, M; Tendillo, FJ1
Bergfeld, C; Beyerbach, M; Kästner, SB; Kulka, AM; Otto, KA1
Fukuda, M; Kim, SG; Vazquez, AL; Zong, X1
Boku, A; Hanamoto, H; Kudo, C; Morimoto, Y; Niwa, H; Sugimura, M; Toyama, M1
Bergfeld, C; Beyerbach, M; Kästner, SB; Voigt, AM1
Johnson, RJ; Keating, SC; Kerr, CL; McDonell, WN; Valverde, A1
Aithal, HP; Kinjavdekar, P; Pawde, AM; Singh, GD; Singh, J; Tiwary, R; Zama, MM1
Chen, GD; Mao, QJ; Xia, R; Xia, ZY; Xu, W; Yin, H1
Bednarski, RM; Ebner, LS; Hubbell, JA; Lerche, P1
Acevedo-Arcique, CM; Bolio-González, ME; Gutierrez-Blanco, E; Ibancovichi-Camarillo, JA; Marin-Cano, G; Sauri-Arceo, CH; Steagall, PV; Victoria-Mora, JM1
Moens, YP; Pavlidou, K; Raptopoulos, D; Savvas, I; Vasilakos, D1
Duchateau, L; Gasthuys, F; Gozalo-Marcilla, M; Schauvliege, S; Steblaj, B1
Brunetti, A; Gargiulo, S; Gramanzini, M; Greco, A; Liuzzi, R; Vesce, G1
Alibhai, HI; Brodbelt, DC; Jimenez Lozano, A; Mathis, A; Pinelas, R1
Keilholz, SD; Magnuson, ME; Pan, WJ; Thompson, GJ1
Kang, YR; Kim, J; Kim, SY; Koo, BN; Lee, JH1
Beazley, SG; Benmansour, P; Bracamonte, JL; Duke-Novakovski, T; Husulak, ML; Withnall, E1
Chen, W; Han, X; Li, Y; Liu, C; Peng, S; Wang, F; Zeng, M; Zuo, Z1
Duke-Novakovski, T; Palacios-Jimenez, C; Rymes, L; Sanchez-Teran, AF; Wetzel, T1
Cao, D; Han, X; Li, Y; Liao, Z; Liu, C; Peng, J; Wang, F; Zuo, Z1
Pascoe, PJ1
Ham, SY; Kim, JE; Park, C; Shim, YH; Shin, MJ1
Ahmed, S; Burgoyne, LL; Chooi, C; Costi, D; Cyna, AM; Ellwood, J; Larsson, JN; Middleton, P; Stephens, K; Strickland, P1
Ide, R; Saiki, C; Takahashi, M; Tamiya, J1
Acevedo-Arcique, CM; Chavez, JR; Gutierrez-Blanco, E; Ibancovichi, JA; Moran-Muñoz, R; Sanchez-Aparicio, P; Santos-González, M; Tendillo-Cortijo, F; Victoria-Mora, JM1
Cândido, TD; Diniz, MS; Fantoni, DT; Teixeira, LR; Teixeira-Neto, FJ; Zanuzzo, FS1
Baron-Hionis, N; Beck, SG; Chalifoux, MR; Contreras, D; Han, B; Kelz, MB; McCarren, HS; Meng, QC; Moore, JT; Sedigh-Sarvestani, M1
Chatterjee, N; Dash, PK; Easwer, HV; Ganesamoorthi, A; Gopalakrishna, KN1
Constable, PD; Grasso, SC; Ko, JC; Paranjape, V; Weil, AB1
Edginton, A; Johnson, R; Keating, S; Kerr, C; Knych, H; McDonell, W; Valverde, A1
Byon, HJ; Kim, HS; Kim, JE; Kim, JT; Lee, JH; Park, YH1
Keilholz, SD; Pan, WJ; Thompson, GJ1
Diao, HX; Fan, HG; Gao, PY; Jiang, S; Li, JN; Liu, HY1
Adesina, A; Akinkuotu, AC; Lazar, DA; Olutoye, OA; Olutoye, OO1
Ehrenfeld, JM; Tabing, AK; Wanderer, JP3
Hamblin, R; Merry, AF1
Li, H; Wu, H; Xia, R; Xia, Z; Xia, ZY; Xiao, X; Xu, J; Yin, H; Zhang, L; Zhou, D1
Cheng, D; Martin, J1
Dexter, F; Epstein, RH1
Bala, I; Bhatia, N; Dwivedi, D; Makkar, JK; Singh, PM1
Haga, HA; Krontveit, RI; Lervik, A; Ranheim, B; Risberg, ÅI1
Carette, R; De Medts, R; De Wolf, AM; Hendrickx, JF1
McConachie, I1
Fox, L; Mans, C; Snyder, LB1
Hara, M; Hemmings, HC; Zhou, ZY1
Honkavaara, J; Ilkiw, JE; Pypendop, BH1
Alcorn, J; Benmansour, P; Billinsky, J; Duke-Novakovski, T1
Brynildsen, JK; Hsu, LM; Lu, H; Ross, TJ; Stein, EA; Yang, Y1
Bao, H; Chen, L; Han, L; Ji, M; Si, Y; Sun, F; Xu, Y; Yang, J; Zhang, Y1
Anghelescu, DL; Moore, AD1
Aristizabal, F; Cenani, A; Guedes, AGP; Nieto, J; Tearney, CC1
Hamilton, C; Ma, Y; Zhang, N1
Covey-Crump, G; Khenissi, L; Knowles, TG; Murrell, J1
Bailey, RS; Barter, LS; Pypendop, BH1
Campoy, L; Honkavaara, J; Martin-Flores, M; Sakai, DM1
Barbosa, VF; de Araujo, NLLC; Dórea Neto, FA; Martins Filho, EF; Oriá, AP; Otero, AR; Schäffer, DPH1
Al-Bizri, E; Benveniste, H; Ding, F; Lee, H; Lu, H; Makaryus, R; Nedergaard, M; Probst, S; Stein, EA; Sun, Q1
Honkavaara, J; Ilkiw, JE; Pypendop, BH; Siao, KT1
Bennett, RC; Kuusela, E; Raekallio, MR; Salla, KM; Scheinin, M; Tuns, CI; Vainio, OM1
Geburek, F; Hopster, K; Hopster-Iversen, C; Kästner, SBR; Wittenberg-Voges, L1
Chai, X; Han, M; Huang, X; Kang, F; Li, J; Tang, C1
Hopster, K; Kästner, SB; Raekallio, M; Rohn, K; Vainio, OM; Wittenberg-Voges, L1
Coursey, CD; Kiehl, WM; Moore, EJ; Scallan, EM; Simon, BT1
Hopster, K; Kästner, SBR; Neudeck, S; Rohn, K; Wittenberg-Voges, L1
Boesch, JM; Kollias, G; Parker, C; Peralta, S; Romano, M1
Boysen, SR; Caulkett, NA; Duval, JD; Pang, JM1
Campoy, L; Gleed, RD; Honkavaara, J; Martin-Flores, M; Portela, DA; Sakai, DM1
Banks, MI; Grady, SM; Krause, BM; Manning, KA; Moran, NS; Uhlrich, DJ1
Beaufrere, H; Browning, GR; Eshar, D1
Ambrosini, F; Carvalho, ER; Champion, T; D'Otaviano de Castro Vilani, RG; da Silva, GA; Freitas, GC1
Lin, T; Liu, C; Zhou, Z1
Abraham, AM; Aguirre, JI; Castillo, EJ; Grove, K; Jiron, JM; Malinowski, C; Malphurs, WL; Mendieta Calle, JL; Messer, JG; Reznikov, LR; Zubcevic, J1
Gao, L; Liu, H; Shan, Y; Tang, Z; Wang, X1
Finley, J1
Ahokoivu, H; Honkavaara, J; Pypendop, BH2
Dzirasa, K; Han, BX; Jiang-Xie, LF; Prevosto, V; Wang, F; Yin, L; Zhao, S1
Campoy, L; Martin-Flores, M; Parry, S; Sakai, DM; Zatroch, KK1
Kästner, SBR; Raue, JF; Tarvainen, MP1
Bettembourg, V; Dulgheriu, D; Haga, HA1
Ahokoivu, H; Honkavaara, J; Jaeger, AT; Pypendop, BH1
Beaufrère, H; Browning, GR; Eshar, D; Meekins, JM; Roberts, JK1
Downs, JC; Girkin, CA; Jasien, JV1
Liu, H; Pang, X; Zhang, P; Zhao, J; Zhou, Y1
Beaufrère, H; Browning, GR; Eshar, D; Ross, E; Thomason, JD1
Cui, D; Gao, Y; Han, H; Li, Y; Sun, M; Yang, J; Zhao, G; Zou, J1
Allweiler, S; Almeida, DC; Baldo, CF; Guedes, A; Knych, H; Tucker, L; Wendt-Hornickle, E1
Evelhoch, JL; Hines, CDG; Houghton, AK; Hyde, LA; Kennedy, ME; Lu, S; Meng, X; Zhao, F1
Bruns, TM; Kennedy, E; Lester, PA; Martin, T; Ouyang, Z; Xu, JJ; Yousuf, Z1
Kästner, SBR; Raue, JF; Tünsmeyer, J1
Benveniste, H; Dai, F; Koundal, S; Lee, H; Monte, B; Ozturk, BO1
Arroyo, L; Hanna, B; Hopkins, A; O'Sullivan, ML; Tisotti, T; Valverde, A1
Haga, HA; Lervik, A; Nordgreen, J1
Duke-Novakovski, T; Fujiyama, M; Jones, T1
Keating, SCJ; Kerr, CL1
Cui, Y; Ju, S; Lu, CQ; Luan, Y; Meng, XP; Xu, XM; Zeng, CH1
Kästner, S; Kopp, V; Neudeck, S; Twele, L1
Im, GH; Kim, SG; You, T1
Chang, CC; Huang, HY; Liao, KY; Shia, WY; Wang, HC1
Kobluk, K; Pypendop, BH1
Campagna, I; Hartnack, S; Kutter, AP; Steblaj, B1
Ağar, E; Al-Gailani, L; Al-Kaleel, A; Arslan, G; Ayyıldız, M1
Amari, M; Brioschi, FA; Cagnardi, P; De Zani, D; Di Cesare, F; Di Giancamillo, M; Rabbogliatti, V; Ravasio, G; Zani, DD1
Hector, RC; Hess, AM; Kramer, BM; Mama, KR; Rezende, ML1
Hou, B; Huang, H; Min, J; Shi, X; Zhang, Q; Zhang, Y; Zhu, Y1
Ambrósio, AM; de Olveira, CM; Fantoni, DT; Gonçalves, LA; Nagashima, JK; Pereira, MA; Talib, MS1
Honkavaara, J; Huuskonen, V; Pesonen, T; Raekallio, M; Restitutti, F; Vainio, O1
Amari, M; Bonato, F; Brioschi, FA; Di Cesare, F; Giordano, A; Magnone, W; Moretti, P; Pecile, A; Rabbogliatti, V; Ravasio, G1
Haga, Y; Hagiya, K; Hata, J; Kaneko, T; Kawaguchi, N; Komaki, Y; Miyabe-Nishiwaki, T; Muta, K; Okano, H; Okano, HJ; Seki, F; Yoshimaru, D1
Bengono Bengono, RS; Metogo, JM; Minkande, JZ; Ndikontar, R; Ngouatna, S; Ntock, FN; Tochie, JN1
Ahmad, M; Aroosa, S; Hafeez, MA; Javeed, A; Sattar, A; Usman, M1
Balthazar, DA; da Silva, MOL; de Menezes, TQ; Freitas, MM; Gomes, VH; Morais, TDN; Stocco, AV1
Du, C; Koretsky, AP; Ling, H; Pan, Y; Park, K; Ren, J; Volkow, ND1
Le Chevallier, D; MacFarlane, PD; van Oostrom, H1
Cho, AJ; Dillon, EJ; Dong, Y; Edlow, AG; Ichinose, F; Mallari, OG; Solt, K; Stewart, VG; Vincent, KF; Xie, Z1
Anumba, N; Keilholz, S; LaGrow, TJ; Maltbie, E; Pan, WJ; Xu, N1

Reviews

5 review(s) available for dexmedetomidine and isoflurane

ArticleYear
Heart block and prolonged Q-Tc interval following muscle relaxant reversal: a case report.
    AANA journal, 2008, Volume: 76, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Atropine; Cholinesterase Inhibitors; Desflurane; Dexmedetomidine; Droperidol; Drug Monitoring; Electrocardiography; Female; Gastric Bypass; Heart Block; Humans; Hypnotics and Sedatives; Indoles; Isoflurane; Long QT Syndrome; Muscarinic Antagonists; Neostigmine; Nurse Anesthetists; Obesity, Morbid; Quinolizines; Risk Factors; Serotonin Antagonists

2008
Traumatic brain injury: neuroprotective anaesthetic techniques, an update.
    Injury, 2009, Volume: 40 Suppl 4

    Topics: Adolescent; Adult; Brain Injuries; Cell Death; Central Nervous System Depressants; Craniocerebral Trauma; Cyclosporine; Dexmedetomidine; Erythropoietin; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Intracranial Hypotension; Isoflurane; Middle Aged; Neuroprotective Agents; Nitrous Oxide; Perioperative Care; Propofol; Resuscitation; Saline Solution, Hypertonic; Xenon; Young Adult

2009
Considerations for the use of anesthetics in neurotoxicity studies.
    Comparative medicine, 2010, Volume: 60, Issue:4

    Topics: Anesthetics; Barbiturates; Carbon Dioxide; Dexmedetomidine; Euthanasia, Animal; Halothane; Isoflurane; Ketamine; Nervous System; Neuroprotective Agents; Nitrous Oxide; Propofol; Research; Signal Transduction; Toxicology; Xenon

2010
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child; Clonidine; Desflurane; Dexmedetomidine; Halothane; Humans; Isoflurane; Methyl Ethers; Midazolam; Propofol; Sevoflurane

2014
Emergence Delirium in Pediatric Anesthesia.
    Paediatric drugs, 2017, Volume: 19, Issue:1

    Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence Delirium; Fentanyl; Humans; Incidence; Isoflurane; Ketamine; Methyl Ethers; Propofol; Sevoflurane

2017

Trials

73 trial(s) available for dexmedetomidine and isoflurane

ArticleYear
Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. 1: Pharmacodynamic and pharmacokinetic interactions.
    British journal of anaesthesia, 1999, Volume: 83, Issue:3

    Topics: Adrenergic alpha-Agonists; Adult; Anesthetics, Inhalation; Cross-Over Studies; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Hemodynamics; Humans; Isoflurane; Male

1999
Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. 2: Auditory and somatosensory evoked responses.
    British journal of anaesthesia, 1999, Volume: 83, Issue:3

    Topics: Adrenergic alpha-Agonists; Adult; Anesthetics, Inhalation; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Interactions; Evoked Potentials; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Humans; Isoflurane; Male

1999
Comparison of medetomidine and dexmedetomidine as premedication in isoflurane anaesthesia for orthopaedic surgery in domestic sheep.
    Journal of veterinary medicine. A, Physiology, pathology, clinical medicine, 2001, Volume: 48, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypnotics and Sedatives; Infusions, Intravenous; Isoflurane; Medetomidine; Orthopedics; Premedication; Sheep

2001
Clinical comparison of preanaesthetic intramuscular medetomidine and dexmedetomidine in domestic sheep.
    DTW. Deutsche tierarztliche Wochenschrift, 2001, Volume: 108, Issue:10

    Topics: Adrenergic alpha-Agonists; Anesthetics, Inhalation; Animals; Blood Pressure; Dexmedetomidine; Female; Heart Rate; Hypnotics and Sedatives; Injections, Intramuscular; Isoflurane; Medetomidine; Preanesthetic Medication; Sheep

2001
24-hour Holter-monitoring in the perianaesthetic period in dogs premedicated with dexmedetomidine.
    Veterinary journal (London, England : 1997), 2002, Volume: 164, Issue:3

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Dexmedetomidine; Dogs; Drug Interactions; Drug Monitoring; Female; Heart Rate; Hypnotics and Sedatives; Isoflurane; Male; Preanesthetic Medication; Propofol; Time Factors

2002
A comparison of propofol infusion and propofol/isoflurane anaesthesia in dexmedetomidine premedicated dogs.
    Journal of veterinary pharmacology and therapeutics, 2003, Volume: 26, Issue:3

    Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; beta-Endorphin; Blood Gas Analysis; Blood Pressure; Catecholamines; Dexmedetomidine; Dogs; Drug Administration Schedule; Female; Heart Rate; Hydrocortisone; Hypnotics and Sedatives; Infusions, Intravenous; Injections, Intramuscular; Isoflurane; Male; Premedication; Propofol

2003
Changes in the minimum alveolar concentration of isoflurane and some cardiopulmonary measurements during three continuous infusion rates of dexmedetomidine in dogs.
    Veterinary anaesthesia and analgesia, 2006, Volume: 33, Issue:2

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Bicarbonates; Blood Pressure; Carbon Dioxide; Dexmedetomidine; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Heart Rate; Hypnotics and Sedatives; Isoflurane; Lactic Acid; Oxygen; Respiration

2006
Fentanyl or dexmedetomidine combined with desflurane for bariatric surgery.
    Journal of clinical anesthesia, 2006, Volume: 18, Issue:1

    Topics: Adrenergic alpha-Agonists; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Combined; Anesthetics, Inhalation; Blood Pressure; Desflurane; Dexmedetomidine; Double-Blind Method; Electroencephalography; Female; Fentanyl; Gastric Bypass; Heart Rate; Humans; Hypnotics and Sedatives; Isoflurane; Male; Middle Aged; Obesity, Morbid; Pain, Postoperative

2006
Dexmedetomidine or medetomidine premedication before propofol-desflurane anaesthesia in dogs.
    Journal of veterinary pharmacology and therapeutics, 2006, Volume: 29, Issue:3

    Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Blood Pressure; Desflurane; Dexmedetomidine; Dogs; Female; Heart Rate; Hemodynamics; Hypnotics and Sedatives; Isoflurane; Male; Medetomidine; Preanesthetic Medication; Propofol; Respiration

2006
Response entropy is more reactive than bispectral index during laparoscopic gastric banding.
    Journal of clinical monitoring and computing, 2006, Volume: 20, Issue:4

    Topics: Adult; Analgesics, Non-Narcotic; Anesthesia; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Bariatric Surgery; Desflurane; Dexmedetomidine; Drug Therapy, Computer-Assisted; Electroencephalography; Entropy; Female; Fentanyl; Humans; Isoflurane; Laparoscopy; Male

2006
Autonomic activity during dexmedetomidine or fentanyl infusion with desflurane anesthesia.
    Journal of clinical anesthesia, 2007, Volume: 19, Issue:1

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Analgesics, Opioid; Analysis of Variance; Anesthesia, General; Anesthetics, Inhalation; Autonomic Nervous System; Desflurane; Dexmedetomidine; Electroencephalography; Female; Fentanyl; Gastroplasty; Heart Rate; Humans; Intraoperative Period; Isoflurane; Laparoscopy; Male; Middle Aged; Obesity, Morbid; Prospective Studies; Single-Blind Method

2007
Dexmedetomidine infusion as a supplement to isoflurane anaesthesia for vitreoretinal surgery.
    British journal of anaesthesia, 2007, Volume: 98, Issue:4

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adult; Anesthesia Recovery Period; Anesthetics, Inhalation; Blood Pressure; Device Removal; Dexmedetomidine; Double-Blind Method; Female; Humans; Intraocular Pressure; Intubation, Intratracheal; Isoflurane; Male; Middle Aged; Retina; Vitreous Body

2007
Hemodynamic and respiratory changes following dexmedetomidine administration during general anesthesia: sevoflurane vs desflurane.
    Paediatric anaesthesia, 2007, Volume: 17, Issue:5

    Topics: Analgesics, Non-Narcotic; Anesthesia, General; Anesthetics, Inhalation; Blood Pressure; Carbon Dioxide; Child; Child, Preschool; Cohort Studies; Desflurane; Dexmedetomidine; Electroencephalography; Female; Heart Rate; Humans; Infant; Intubation, Intratracheal; Isoflurane; Male; Methyl Ethers; Prospective Studies; Respiration; Sevoflurane; Time Factors

2007
Effects of epidural administration of dexmedetomidine on the minimum alveolar concentration of isoflurane in dogs.
    American journal of veterinary research, 2007, Volume: 68, Issue:12

    Topics: Analgesics, Non-Narcotic; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dexmedetomidine; Dogs; Female; Injections, Epidural; Isoflurane; Male; Pulmonary Alveoli

2007
Dexmedetomidine constant rate infusion for 24 hours during and after propofol or isoflurane anaesthesia in dogs.
    Veterinary anaesthesia and analgesia, 2008, Volume: 35, Issue:2

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Cross-Over Studies; Dexmedetomidine; Dogs; Female; Heart Rate; Hypnotics and Sedatives; Infusions, Intravenous; Isoflurane; Male; Oxygen; Propofol; Prospective Studies; Respiration; Treatment Outcome

2008
Dexmedetomidine continuous rate infusion during isoflurane anaesthesia in canine surgical patients.
    Veterinary anaesthesia and analgesia, 2008, Volume: 35, Issue:1

    Topics: Adrenergic alpha-Agonists; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Animals; Dexmedetomidine; Dogs; Female; Heart Rate; Infusions, Intravenous; Isoflurane; Male; Preanesthetic Medication; Prospective Studies; Treatment Outcome

2008
Motor and somatosensory evoked potentials are well maintained in patients given dexmedetomidine during spine surgery.
    Anesthesiology, 2008, Volume: 109, Issue:3

    Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Anesthetics, Intravenous; Area Under Curve; Cross-Over Studies; Desflurane; Dexmedetomidine; Dose-Response Relationship, Drug; Electrocardiography; Evoked Potentials, Motor; Evoked Potentials, Somatosensory; Female; Humans; Isoflurane; Male; Middle Aged; Piperidines; Reaction Time; Remifentanil; Single-Blind Method; Spine

2008
Induced hypotension in orthognathic surgery: a comparative study of 2 pharmacological protocols.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2008, Volume: 66, Issue:11

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; Clonidine; Dexmedetomidine; Female; Heart Rate; Humans; Hypotension, Controlled; Isoflurane; Male; Oral Surgical Procedures; Piperidines; Remifentanil

2008
Effect of epidural dexmedetomidine on intraoperative awareness and post-operative pain after one-lung ventilation.
    Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Analgesics, Non-Narcotic; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Inhalation; Awareness; Bupivacaine; Consciousness Monitors; Dexmedetomidine; Hemodynamics; Humans; Hypnotics and Sedatives; Hypoxia; Intraoperative Complications; Isoflurane; Male; Middle Aged; Pain, Postoperative; Respiration, Artificial; Single-Blind Method; Thoracic Surgical Procedures

2010
Cardiopulmonary and isoflurane-sparing effects of epidural or intravenous infusion of dexmedetomidine in cats undergoing surgery with epidural lidocaine.
    Veterinary anaesthesia and analgesia, 2010, Volume: 37, Issue:2

    Topics: Analgesics, Non-Narcotic; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Animals; Blood Gas Analysis; Cats; Dexmedetomidine; Female; Heart Rate; Hysterectomy; Infusions, Intravenous; Injections, Epidural; Isoflurane; Lidocaine; Ovariectomy; Respiratory Rate

2010
Effect of dexmedetomidine on the minimum alveolar concentration of isoflurane in cats.
    Journal of veterinary pharmacology and therapeutics, 2012, Volume: 35, Issue:2

    Topics: Analgesics, Non-Narcotic; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Cats; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Isoflurane; Pulmonary Alveoli

2012
Hemodynamic effects of dexmedetomidine in isoflurane-anesthetized cats.
    Veterinary anaesthesia and analgesia, 2011, Volume: 38, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Cats; Dexmedetomidine; Female; Hemodynamics; Infusions, Intravenous; Isoflurane; Least-Squares Analysis; Prospective Studies

2011
Influence of a constant rate infusion of dexmedetomidine on cardiopulmonary function and recovery quality in isoflurane anaesthetized horses.
    Veterinary anaesthesia and analgesia, 2012, Volume: 39, Issue:1

    Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Dexmedetomidine; Dobutamine; Heart; Heart Rate; Horses; Hypnotics and Sedatives; Infusions, Intravenous; Isoflurane; Ketamine; Respiration; Single-Blind Method

2012
Pharmacokinetics of dexmedetomidine administered intravenously in isoflurane-anesthetized cats.
    American journal of veterinary research, 2012, Volume: 73, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Area Under Curve; Cats; Dexmedetomidine; Female; Half-Life; Hypnotics and Sedatives; Injections, Intravenous; Isoflurane

2012
Clinical efficacy and safety of dexmedetomidine used as a preanesthetic prior to general anesthesia in cats.
    Journal of the American Veterinary Medical Association, 2012, Feb-15, Volume: 240, Issue:4

    Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Combined; Animals; Blood Gas Analysis; Cats; Dexmedetomidine; Female; Heart Rate; Hypnotics and Sedatives; Isoflurane; Ketamine; Male; Pain, Postoperative; Preanesthetic Medication; Propofol; Respiratory Rate

2012
Isoflurane but not halothane minimum alveolar concentration-sparing response of dexmedetomidine is enhanced in rats chronically treated with selective α2-adrenoceptor agonist.
    Laboratory animals, 2012, Volume: 46, Issue:3

    Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Female; Halothane; Injections, Intraperitoneal; Isoflurane; Pulmonary Alveoli; Rats; Rats, Wistar; Specific Pathogen-Free Organisms

2012
Effects of isoflurane with and without dexmedetomidine or remifentanil on heart rate variability before and after nociceptive stimulation at different multiples of minimum alveolar concentration in dogs.
    American journal of veterinary research, 2013, Volume: 74, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cross-Over Studies; Dexmedetomidine; Dogs; Drug Therapy, Combination; Female; Heart Rate; Isoflurane; Male; Pain; Piperidines; Pulmonary Alveoli; Remifentanil

2013
Clinicophysiological and haemodynamic effects of fentanyl with xylazine, medetomidine and dexmedetomidine in isoflurane-anaesthetised water buffaloes (Bubalus bubalis).
    Journal of the South African Veterinary Association, 2013, Mar-18, Volume: 84, Issue:1

    Topics: Adjuvants, Anesthesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Buffaloes; Dexmedetomidine; Fentanyl; Heart Rate; Hypnotics and Sedatives; Isoflurane; Male; Medetomidine; Respiration

2013
Effect of intravenous infusion of dexmedetomidine combined with inhalation of isoflurane on arterial oxygenation and intrapulmonary shunt during single-lung ventilation.
    Cell biochemistry and biophysics, 2013, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Blood Gas Analysis; Bronchoscopy; Dexmedetomidine; Female; Hemodynamics; Humans; Infusions, Intravenous; Isoflurane; Lung; Male; Middle Aged; One-Lung Ventilation; Oxygen; Young Adult

2013
Effect of dexmedetomidine, morphine-lidocaine-ketamine, and dexmedetomidine-morphine-lidocaine-ketamine constant rate infusions on the minimum alveolar concentration of isoflurane and bispectral index in dogs.
    American journal of veterinary research, 2013, Volume: 74, Issue:7

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Local; Animals; Consciousness Monitors; Cross-Over Studies; Dexmedetomidine; Dogs; Drug Interactions; Drug Therapy, Combination; Female; Isoflurane; Ketamine; Lidocaine; Male; Morphine; Pulmonary Alveoli

2013
Evaluation of the isoflurane-sparing effects of fentanyl, lidocaine, ketamine, dexmedetomidine, or the combination lidocaine-ketamine-dexmedetomidine during ovariohysterectomy in dogs.
    Veterinary anaesthesia and analgesia, 2013, Volume: 40, Issue:6

    Topics: Anesthesia, General; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Dexmedetomidine; Dogs; Female; Fentanyl; Hysterectomy; Isoflurane; Ketamine; Lidocaine; Ovariectomy

2013
Comparison of the influence of two different constant-rate infusions (dexmedetomidine versus morphine) on anaesthetic requirements, cardiopulmonary function and recovery quality in isoflurane anaesthetized horses.
    Research in veterinary science, 2013, Volume: 95, Issue:3

    Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Dexmedetomidine; Heart; Horses; Hypnotics and Sedatives; Isoflurane; Ketamine; Lung; Morphine; Narcotics

2013
Effects of different doses of dexmedetomidine on anaesthetic induction with alfaxalone--a clinical trial.
    Veterinary anaesthesia and analgesia, 2014, Volume: 41, Issue:4

    Topics: Anesthetics; Anesthetics, Inhalation; Animals; Dexmedetomidine; Dogs; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Isoflurane; Methadone; Pregnanediones

2014
Low-dose dexmedetomidine reduces emergence agitation after desflurane anaesthesia in children undergoing strabismus surgery.
    Yonsei medical journal, 2014, Volume: 55, Issue:2

    Topics: Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child, Preschool; Desflurane; Dexmedetomidine; Female; Fentanyl; Humans; Infant; Intraoperative Period; Isoflurane; Male; Ophthalmologic Surgical Procedures; Propofol; ROC Curve; Strabismus

2014
Cardiopulmonary effects of an infusion of remifentanil or morphine in horses anesthetized with isoflurane and dexmedetomidine.
    Veterinary anaesthesia and analgesia, 2014, Volume: 41, Issue:4

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Cross-Over Studies; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Rate; Horses; Isoflurane; Male; Morphine; Piperidines; Remifentanil

2014
Cardiopulmonary effects of dexmedetomidine and ketamine infusions with either propofol infusion or isoflurane for anesthesia in horses.
    Veterinary anaesthesia and analgesia, 2015, Volume: 42, Issue:1

    Topics: Animals; Blood Pressure; Body Temperature; Cross-Over Studies; Dexmedetomidine; Female; Heart Rate; Horses; Isoflurane; Ketamine; Male; Propofol

2015
The cardiopulmonary effects of dexmedetomidine infusions in dogs during isoflurane anesthesia.
    Veterinary anaesthesia and analgesia, 2015, Volume: 42, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dexmedetomidine; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hypnotics and Sedatives; Infusions, Intravenous; Isoflurane; Respiration

2015
Dexmedetomidine does not reduce emergence agitation in adults following orthognathic surgery.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:8

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Cough; Delayed Emergence from Anesthesia; Desflurane; Dexmedetomidine; Double-Blind Method; Drug Synergism; Female; Humans; Intubation, Intratracheal; Isoflurane; Male; Middle Aged; Orthognathic Surgical Procedures; Pain Measurement; Piperidines; Psychomotor Agitation; Remifentanil; Tachycardia; Young Adult

2014
Effects of a dexmedetomidine constant rate infusion and atropine on changes in global perfusion variables induced by hemorrhage followed by volume replacement in isoflurane-anesthetized dogs.
    American journal of veterinary research, 2014, Volume: 75, Issue:11

    Topics: Adjuvants, Anesthesia; Anesthesia; Anesthetics, Inhalation; Animals; Atropine; Cross-Over Studies; Dexmedetomidine; Dogs; Female; Hemodynamics; Infusions, Intravenous; Isoflurane; Male

2014
Dexmedetomidine as an Anesthetic Adjuvant in Patients Undergoing Transsphenoidal Resection of Pituitary Tumor.
    Journal of neurosurgical anesthesiology, 2015, Volume: 27, Issue:3

    Topics: Adjuvants, Anesthesia; Adult; Analysis of Variance; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Dexmedetomidine; Double-Blind Method; Fentanyl; Hemodynamics; Humans; Hypnotics and Sedatives; Isoflurane; Middle Aged; Natural Orifice Endoscopic Surgery; Pituitary Neoplasms; Prospective Studies; Sodium Chloride; Sphenoid Sinus

2015
Hemodynamic influence of acepromazine or dexmedetomidine premedication in isoflurane-anesthetized dogs.
    Journal of the American Veterinary Medical Association, 2015, Apr-01, Volume: 246, Issue:7

    Topics: Acepromazine; Anesthesia, Inhalation; Animals; Blood Pressure; Cardiac Output; Cross-Over Studies; Dexmedetomidine; Dogs; Female; Isoflurane; Male; Premedication

2015
Effects of acepromazine or dexmedetomidine on fentanyl disposition in dogs during recovery from isoflurane anesthesia.
    Veterinary anaesthesia and analgesia, 2016, Volume: 43, Issue:1

    Topics: Acepromazine; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cross-Over Studies; Dexmedetomidine; Dogs; Double-Blind Method; Fentanyl; Hypnotics and Sedatives; Isoflurane; Male

2016
Appropriate dose of dexmedetomidine for the prevention of emergence agitation after desflurane anesthesia for tonsillectomy or adenoidectomy in children: up and down sequential allocation.
    BMC anesthesiology, 2015, May-27, Volume: 15

    Topics: Adenoidectomy; Anesthetics, Inhalation; Child; Child, Preschool; Desflurane; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Isoflurane; Male; Methyl Ethers; Psychomotor Agitation; Sevoflurane; Tonsillectomy

2015
Comparison of the effects of propofol and emulsified isoflurane alone or combined with dexmedetomidine on induction of anesthesia in dogs.
    Veterinary anaesthesia and analgesia, 2016, Volume: 43, Issue:2

    Topics: Anesthesia; Anesthetics, Combined; Animals; Dexmedetomidine; Dogs; Isoflurane; Propofol; Prospective Studies

2016
Intravenous Infusion of Dexmedetomidine Combined Isoflurane Inhalation Reduces Oxidative Stress and Potentiates Hypoxia Pulmonary Vasoconstriction during One-Lung Ventilation in Patients.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Adult; Anesthetics, Inhalation; Dexmedetomidine; Humans; Infusions, Intravenous; Isoflurane; Male; Middle Aged; One-Lung Ventilation; Oxidative Stress; Vasoconstriction

2015
A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children.
    Anaesthesia, 2016, Volume: 71, Issue:1

    Topics: Anesthetics, Inhalation; Child; Child, Preschool; Delirium; Desflurane; Dexmedetomidine; Female; Humans; Isoflurane; Male; Propofol

2016
The cardiovascular status of isoflurane-anaesthetized horses with and without dexmedetomidine constant rate infusion evaluated at equivalent depths of anaesthesia.
    Veterinary anaesthesia and analgesia, 2016, Volume: 43, Issue:4

    Topics: Acepromazine; Analgesics, Non-Narcotic; Anesthesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Arterial Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Cross-Over Studies; Dexmedetomidine; Dopamine Antagonists; Horses; Isoflurane; Ketamine; Midazolam; Pain Measurement; Preanesthetic Medication

2016
Blood concentrations of remifentanil during and after infusion in horses anesthetized with isoflurane and dexmedetomidine.
    Research in veterinary science, 2016, Volume: 107

    Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Dexmedetomidine; Diazepam; Drug Interactions; Female; Half-Life; Horses; Isoflurane; Ketamine; Male; Piperidines; Remifentanil; Xylazine

2016
Comparison between the effects of postanesthetic xylazine and dexmedetomidine on characteristics of recovery from sevoflurane anesthesia in horses.
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:2

    Topics: Anesthesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Cross-Over Studies; Dexmedetomidine; Horses; Isoflurane; Male; Methyl Ethers; Sevoflurane; Xylazine

2017
Do heat and moisture exchangers in the anaesthesia breathing circuit preserve body temperature in dogs undergoing anaesthesia for magnetic resonance imaging?
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:3

    Topics: Anesthesia, Closed-Circuit; Anesthesia, General; Anesthetics, Inhalation; Animals; Body Temperature; Dexmedetomidine; Dogs; Female; Hypnotics and Sedatives; Isoflurane; Magnetic Resonance Imaging; Male; Premedication; Prospective Studies; Rectum; Time Factors

2017
Hemodynamic effects of dexmedetomidine, with and without MK-467, following intramuscular administration in cats anesthetized with isoflurane.
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:5

    Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Pressure; Cats; Cross-Over Studies; Deep Sedation; Dexmedetomidine; Hemodynamics; Hypnotics and Sedatives; Injections, Intramuscular; Isoflurane; Male; Quinolizines; Vascular Resistance

2017
Cardiovascular effects of premedication with medetomidine alone and in combination with MK-467 or glycopyrrolate in dogs subsequently anesthetized with isoflurane.
    American journal of veterinary research, 2017, Volume: 78, Issue:11

    Topics: Adjuvants, Anesthesia; Anesthesia; Animals; Blood Pressure; Cardiovascular System; Cross-Over Studies; Dexmedetomidine; Dogs; Female; Glycopyrrolate; Heart Rate; Hemodynamics; Hypnotics and Sedatives; Isoflurane; Ketamine; Male; Medetomidine; Premedication; Quinolizines

2017
Effects of Dexmedetomidine-Isoflurane versus Isoflurane Anesthesia on Brain Injury After Cardiac Valve Replacement Surgery.
    Journal of cardiothoracic and vascular anesthesia, 2018, Volume: 32, Issue:4

    Topics: Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Brain Injuries; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Valve Prosthesis Implantation; Humans; Inflammation Mediators; Isoflurane; Male; Middle Aged; Prospective Studies; Single-Blind Method; Treatment Outcome

2018
Effect of dexmedetomidine and xylazine followed by MK-467 on gastrointestinal microperfusion in anaesthetized horses.
    Veterinary anaesthesia and analgesia, 2018, Volume: 45, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia; Anesthetics, Combined; Animals; Dexmedetomidine; Female; Gastrointestinal Tract; Horses; Isoflurane; Male; Microcirculation; Oxygen; Prospective Studies; Quinolizines; Xylazine

2018
Cardiopulmonary Effects of a Partial Intravenous Anesthesia Technique for Laboratory Swine.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2018, 07-01, Volume: 57, Issue:4

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Azaperone; Blood Pressure; Cardiac Output; Dexmedetomidine; Female; Heart Rate; Isoflurane; Pregnanediones; Premedication; Prospective Studies; Swine

2018
Comparison of Dexmedetomidine-Ketamine-Midazolam and Isoflurane for Anesthesia of Black-tailed Prairie Dogs (
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2019, 01-01, Volume: 58, Issue:1

    Topics: Anesthesia, Inhalation; Anesthetics; Animals; Body Temperature; Cross-Over Studies; Dexmedetomidine; Female; Heart Rate; Isoflurane; Ketamine; Male; Midazolam; Sciuridae

2019
Comparison of Isoflurane, Ketamine-Dexmedetomidine, and Ketamine-Xylazine for General Anesthesia during Oral Procedures in Rice Rats (
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2019, 01-01, Volume: 58, Issue:1

    Topics: Anesthesia, General; Anesthetics; Anesthetics, Inhalation; Animals; Cross-Over Studies; Dexmedetomidine; Drug Therapy, Combination; Isoflurane; Ketamine; Laboratory Animal Science; Male; Mouth; Rats; Sigmodontinae; Xylazine

2019
Effects of dexmedetomidine, with or without vatinoxan (MK-467), on minimum alveolar concentration of isoflurane in cats.
    Veterinary anaesthesia and analgesia, 2019, Volume: 46, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Cats; Cross-Over Studies; Dexmedetomidine; Drug Interactions; Drug Therapy, Combination; Hypnotics and Sedatives; Isoflurane; Male; Pulmonary Alveoli; Quinolizines

2019
Evaluation of atipamezole as a treatment for dexmedetomidine-induced cardiovascular depression in anesthetized cats.
    American journal of veterinary research, 2019, Volume: 80, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Anesthesia; Animals; Cardiac Output; Cats; Cross-Over Studies; Dexmedetomidine; Female; Heart Rate; Hemodynamics; Imidazoles; Isoflurane; Male; Random Allocation; Vascular Resistance

2019
Pharmacokinetics of dexmedetomidine during administration of vatinoxan in male neutered cats anesthetized with isoflurane.
    Journal of veterinary pharmacology and therapeutics, 2020, Volume: 43, Issue:1

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cats; Dexmedetomidine; Drug Interactions; Hypnotics and Sedatives; Isoflurane; Male; Quinolizines

2020
Plasma concentrations at two dexmedetomidine constant rate infusions in isoflurane anaesthetized horses: a clinical study.
    Veterinary anaesthesia and analgesia, 2019, Volume: 46, Issue:5

    Topics: Anesthesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Dexmedetomidine; Horses; Hypnotics and Sedatives; Isoflurane; Male; Orchiectomy; Prospective Studies; Single-Blind Method; Treatment Outcome

2019
Cardiopulmonary effects of dexmedetomidine, with and without vatinoxan, in isoflurane-anesthetized cats.
    Veterinary anaesthesia and analgesia, 2019, Volume: 46, Issue:6

    Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthetics, Inhalation; Animals; Blood Pressure; Cats; Cross-Over Studies; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Hypnotics and Sedatives; Hypotension; Isoflurane; Male; Quinolizines; Vascular Resistance

2019
Pharmacokinetics and clinical effects of xylazine and dexmedetomidine in horses recovering from isoflurane anesthesia.
    Journal of veterinary pharmacology and therapeutics, 2020, Volume: 43, Issue:4

    Topics: Analgesics; Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Cross-Over Studies; Dexmedetomidine; Female; Horses; Hypnotics and Sedatives; Isoflurane; Male; Xylazine

2020
Use of intravenous lidocaine to treat dexmedetomidine-induced bradycardia in sedated and anesthetized dogs.
    Veterinary anaesthesia and analgesia, 2021, Volume: 48, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Bradycardia; Dexmedetomidine; Dog Diseases; Dogs; Female; Heart Rate; Infusions, Intravenous; Isoflurane; Lidocaine; Prospective Studies

2021
Cardiopulmonary effects of an intravenous infusion of fentanyl in cats during isoflurane anesthesia and with concurrent acepromazine or dexmedetomidine administration during anesthetic recovery.
    American journal of veterinary research, 2021, Volume: 82, Issue:4

    Topics: Acepromazine; Anesthesia; Anesthetics, Inhalation; Animals; Blood Pressure; Cats; Cross-Over Studies; Dexmedetomidine; Fentanyl; Infusions, Intravenous; Isoflurane

2021
Pharmacodynamics and plasma concentrations of dexmedetomidine with or without vatinoxan as a constant-rate infusion in horses anaesthetized with isoflurane-A pilot study.
    Journal of veterinary pharmacology and therapeutics, 2021, Volume: 44, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Dexmedetomidine; Horses; Isoflurane; Pilot Projects; Prospective Studies; Quinolizines

2021
Effect of administering dexmedetomidine with or without atropine on cardiac troponin I level in isoflurane-anesthetized dogs.
    The Journal of veterinary medical science, 2021, Dec-02, Volume: 83, Issue:12

    Topics: Animals; Atropine; Dexmedetomidine; Dogs; Isoflurane; Propofol; Troponin I

2021
Effects of dopamine, norepinephrine or phenylephrine on the prevention of hypotension in isoflurane-anesthetized cats administered vatinoxan or vatinoxan and dexmedetomidine.
    Veterinary anaesthesia and analgesia, 2022, Volume: 49, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Dexmedetomidine; Dopamine; Heart Rate; Hypotension; Isoflurane; Male; Norepinephrine; Phenylephrine; Quinolizines

2022
Sedative and cardiopulmonary effects of intramuscular combinations of hydromorphone, acepromazine, dexmedetomidine, and glycopyrrolate followed by intravenous propofol and inhalant isoflurane anesthesia in healthy dogs.
    American journal of veterinary research, 2022, Aug-18, Volume: 83, Issue:10

    Topics: Acepromazine; Anesthesia; Anesthetics; Animals; Cross-Over Studies; Dexmedetomidine; Dogs; Female; Glycopyrrolate; Heart Rate; Hydromorphone; Hypnotics and Sedatives; Isoflurane; Propofol

2022
Microcirculation assessment of dexmedetomidine constant rate infusion during anesthesia of dogs with sepsis from pyometra: a randomized clinical study.
    Veterinary anaesthesia and analgesia, 2022, Volume: 49, Issue:6

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Dexmedetomidine; Dog Diseases; Dogs; Female; Fentanyl; Isoflurane; Lactates; Microcirculation; Pyometra; Sepsis

2022
Cardiovascular effects of dobutamine, norepinephrine and phenylephrine in isoflurane-anaesthetized dogs administered dexmedetomidine-vatinoxan.
    Veterinary anaesthesia and analgesia, 2022, Volume: 49, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Dexmedetomidine; Dobutamine; Dog Diseases; Dogs; Hypotension; Isoflurane; Norepinephrine; Phenylephrine; Saline Solution

2022
The efficacy and safety of an adapted opioid-free anesthesia regimen versus conventional general anesthesia in gynecological surgery for low-resource settings: a randomized pilot study.
    BMC anesthesiology, 2022, 10-24, Volume: 22, Issue:1

    Topics: Analgesics, Opioid; Anesthesia, General; Clonidine; Dexamethasone; Dexmedetomidine; Diazepam; Female; Fentanyl; Gynecologic Surgical Procedures; Humans; Isoflurane; Ketamine; Lidocaine; Magnesium Sulfate; Pain, Postoperative; Pilot Projects; Propofol; Rocuronium; Saline Solution

2022
Protective Effects of Dexmedetomidine Infusion on Genotoxic Potential of Isoflurane in Patients Undergoing Emergency Surgery.
    International journal of clinical practice, 2023, Volume: 2023

    Topics: Anesthesia, General; Antioxidants; Dexmedetomidine; DNA Damage; Humans; Isoflurane

2023

Other Studies

80 other study(ies) available for dexmedetomidine and isoflurane

ArticleYear
The alpha(2A) adrenoceptor and the sympathetic postganglionic neuron contribute to the development of neuropathic heat hyperalgesia in mice.
    Pain, 2000, Volume: 85, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Animals; Brain Chemistry; Dexmedetomidine; Hot Temperature; Hyperalgesia; Isoflurane; Mice; Mice, Inbred Strains; Neurons; Nociceptors; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nerves; Physical Stimulation; Receptors, Adrenergic, alpha-2; Sympathectomy; Sympathetic Fibers, Postganglionic; Tibial Nerve

2000
Comparison of medetomidine and dexmedetomidine as premedicants in dogs undergoing propofol-isoflurane anesthesia.
    American journal of veterinary research, 2001, Volume: 62, Issue:7

    Topics: Adrenergic alpha-Agonists; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Pressure; Dexmedetomidine; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hypnotics and Sedatives; Isoflurane; Male; Medetomidine; Preanesthetic Medication; Propofol; Respiration; Stereoisomerism

2001
Cardiorespiratory and minimum alveolar concentration sparing effects of a continuous intravenous infusion of dexmedetomidine in halothane or isoflurane-anaesthetized rats.
    Laboratory animals, 2006, Volume: 40, Issue:1

    Topics: Adrenergic alpha-Agonists; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Pressure; Dexmedetomidine; Drug Synergism; Female; Halothane; Heart; Heart Rate; Infusions, Intravenous; Isoflurane; Pulmonary Alveoli; Rats; Rats, Wistar; Respiration; Specific Pathogen-Free Organisms

2006
Management of accidental spinal administration of extended-release epidural morphine.
    Anesthesiology, 2008, Volume: 108, Issue:6

    Topics: Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, Inhalation; Delayed-Action Preparations; Dexmedetomidine; Electroencephalography; Female; Humans; Injections, Spinal; Isoflurane; Medical Errors; Middle Aged; Monitoring, Intraoperative; Morphine; Naloxone; Narcotic Antagonists; Nitrous Oxide; Ovary; Postoperative Complications; Recovery of Function; Respiratory Insufficiency; Time Factors

2008
The effect of prolonged anesthesia with isoflurane, propofol, dexmedetomidine, or ketamine on neural cell proliferation in the adult rat.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:6

    Topics: Age Factors; Anesthetics; Animals; Bromodeoxyuridine; Cell Proliferation; Circadian Rhythm; Dentate Gyrus; Dexmedetomidine; Dose-Response Relationship, Drug; Hippocampus; Immunoenzyme Techniques; Isoflurane; Ketamine; Male; Neurons; Propofol; Rats; Rats, Sprague-Dawley

2008
Expressions of genes encoding drug-metabolizing enzymes are altered after sevoflurane, isoflurane, propofol or dexmedetomidine anesthesia.
    Biomedical research (Tokyo, Japan), 2009, Volume: 30, Issue:1

    Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Dexmedetomidine; Gene Expression Regulation; Isoflurane; Liver; Male; Methyl Ethers; Oligonucleotide Array Sequence Analysis; Propofol; Rats; Rats, Wistar; Sevoflurane; Time Factors

2009
Dexmedetomidine attenuates isoflurane-induced neurocognitive impairment in neonatal rats.
    Anesthesiology, 2009, Volume: 110, Issue:5

    Topics: Animals; Animals, Newborn; Apoptosis; Cognition Disorders; Dexmedetomidine; Isoflurane; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley

2009
Comparison between dexmedetomidine and remifentanil for intraoperative controlled hypotension.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2009, Volume: 67, Issue:11

    Topics: Anesthesia, Intravenous; Anesthetics, Inhalation; Dexmedetomidine; Double-Blind Method; Drug Combinations; Fentanyl; Humans; Hypnotics and Sedatives; Hypotension, Controlled; Intraoperative Care; Isoflurane; Piperidines; Prospective Studies; Remifentanil; Tympanoplasty

2009
Dexmedetomidine provides cortical neuroprotection: impact on anaesthetic-induced neuroapoptosis in the rat developing brain.
    Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:6

    Topics: Androstadienes; Anesthetics, Inhalation; Animals; Apoptosis; Biomarkers; Cells, Cultured; Cerebral Cortex; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Isoflurane; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Staurosporine; Wortmannin

2010
Cardiopulmonary effects of two constant rate infusions of dexmedetomidine in isoflurane anaesthetized ponies.
    Veterinary anaesthesia and analgesia, 2010, Volume: 37, Issue:4

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Blood Pressure; Cardiac Output; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Heart; Horses; Hypnotics and Sedatives; Isoflurane; Ketamine; Lung; Male; Midazolam; Monitoring, Physiologic; Oxygen; Oxygen Consumption; Preanesthetic Medication; Stroke Volume; Vascular Resistance

2010
The influence of a continuous rate infusion of dexmedetomidine on the nociceptive withdrawal reflex and temporal summation during isoflurane anaesthesia in dogs.
    Veterinary anaesthesia and analgesia, 2012, Volume: 39, Issue:4

    Topics: Analgesics, Non-Narcotic; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dexmedetomidine; Dogs; Electromyography; Female; Infusions, Intravenous; Isoflurane; Male; Pain Measurement; Reflex

2012
Dexmedetomidine prevents alterations of intestinal microcirculation that are induced by surgical stress and pain in a novel rat model.
    Anesthesia and analgesia, 2012, Volume: 115, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Inhalation; Animals; Blood Flow Velocity; Blood Pressure; Dexmedetomidine; Disease Models, Animal; Heart Rate; Hypertension; Ileum; Infusions, Intravenous; Intestinal Mucosa; Isoflurane; Male; Microcirculation; Microscopy, Video; Muscle, Smooth; Pain, Postoperative; Perfusion Imaging; Rats; Rats, Wistar; Regional Blood Flow; Splanchnic Circulation; Stress, Physiological; Tachycardia; Time Factors; Vasoconstriction

2012
Effects of isoflurane anesthesia with and without dexmedetomidine or remifentanil on quantitative electroencephalographic variables before and after nociceptive stimulation in dogs.
    American journal of veterinary research, 2012, Volume: 73, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Cerebral Cortex; Dexmedetomidine; Dogs; Electroencephalography; Female; Isoflurane; Male; Nociception; Piperidines; Pulmonary Alveoli; Remifentanil; Ulna

2012
Effects of the α₂-adrenergic receptor agonist dexmedetomidine on neural, vascular and BOLD fMRI responses in the somatosensory cortex.
    The European journal of neuroscience, 2013, Volume: 37, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Inhalation; Animals; Brain Waves; Cerebral Arteries; Cerebral Veins; Dexmedetomidine; Epilepsy; Hindlimb; Isoflurane; Magnetic Resonance Imaging; Male; Nitric Oxide; Oxygen; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Vasoconstriction; Vasodilation

2013
Anesthetic effects on susceptibility to cortical spreading depression.
    Neuropharmacology, 2013, Volume: 67

    Topics: Anesthetics; Animals; Cortical Spreading Depression; Dexmedetomidine; Isoflurane; Male; Pentobarbital; Propofol; Rats; Rats, Sprague-Dawley

2013
Cardiopulmonary effects of intravenous fentanyl infusion in dogs during isoflurane anesthesia and with concurrent acepromazine or dexmedetomidine administration during anesthetic recovery.
    American journal of veterinary research, 2013, Volume: 74, Issue:5

    Topics: Acepromazine; Adrenergic alpha-2 Receptor Agonists; Anesthesia, Inhalation; Anesthetics, Intravenous; Animals; Blood Pressure; Dexmedetomidine; Dogs; Dopamine Antagonists; Drug Therapy, Combination; Fentanyl; Heart Rate; Isoflurane; Male

2013
The effect of four anaesthetic protocols for maintenance of anaesthesia on trans-diaphragmatic pressure in dogs.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Anesthesia; Anesthetics; Animals; Dexmedetomidine; Dogs; Female; Fentanyl; Isoflurane; Ketamine; Male; Morphine; Propofol

2013
Effects of some anesthetic agents on skin microcirculation evaluated by laser Doppler perfusion imaging in mice.
    BMC veterinary research, 2013, Dec-17, Volume: 9

    Topics: Acepromazine; Anesthetics; Anesthetics, Inhalation; Animals; Dexmedetomidine; Female; Hypnotics and Sedatives; Imidazoles; Isoflurane; Male; Mice; Microcirculation; Microvessels; Skin; Ultrasonography, Doppler

2013
Time-dependent effects of isoflurane and dexmedetomidine on functional connectivity, spectral characteristics, and spatial distribution of spontaneous BOLD fluctuations.
    NMR in biomedicine, 2014, Volume: 27, Issue:3

    Topics: Animals; Dexmedetomidine; Isoflurane; Magnetic Resonance Imaging; Male; Nerve Net; Oxygen; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Time Factors

2014
Dexmedetomidine reduces isoflurane-induced neuroapoptosis partly by preserving PI3K/Akt pathway in the hippocampus of neonatal rats.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Anesthetics; Animals; Animals, Newborn; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Dexmedetomidine; Dose-Response Relationship, Drug; Hippocampus; Isoflurane; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction

2014
Both JNK and P38 MAPK pathways participate in the protection by dexmedetomidine against isoflurane-induced neuroapoptosis in the hippocampus of neonatal rats.
    Brain research bulletin, 2014, Volume: 107

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Animals, Newborn; Apoptosis; Dexmedetomidine; Hippocampus; Isoflurane; MAP Kinase Kinase 4; Neurons; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction

2014
Effects of dexmedetomidine on cardiorespiratory regulation in spontaneously breathing newborn rats.
    Paediatric anaesthesia, 2014, Volume: 24, Issue:12

    Topics: Adrenergic alpha-Antagonists; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Animals, Newborn; Dexmedetomidine; Electrocardiography; Female; Heart Rate; Hemodynamics; Hypnotics and Sedatives; Imidazoles; Isoflurane; Pregnancy; Rats; Rats, Wistar; Respiratory Mechanics; Tidal Volume

2014
Lidocaine, dexmedetomidine and their combination reduce isoflurane minimum alveolar concentration in dogs.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Anesthesia, Inhalation; Anesthetics, Combined; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Dexmedetomidine; Dogs; Drug Combinations; Female; Heart Rate; Isoflurane; Lidocaine; Male; Pulmonary Alveoli; Random Allocation

2014
α2-Adrenergic stimulation of the ventrolateral preoptic nucleus destabilizes the anesthetic state.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Dec-03, Volume: 34, Issue:49

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics; Animals; Arousal; Brain Waves; Dexmedetomidine; Electroencephalography; Evoked Potentials, Somatosensory; Isoflurane; Male; Mice; Microinjections; Norepinephrine; Preoptic Area; Receptors, Adrenergic, alpha-2

2014
Different dynamic resting state fMRI patterns are linked to different frequencies of neural activity.
    Journal of neurophysiology, 2015, Volume: 114, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Brain; Brain Mapping; Dexmedetomidine; Dose-Response Relationship, Drug; Electrodes, Implanted; Hypnotics and Sedatives; Isoflurane; Magnetic Resonance Imaging; Male; Rats, Sprague-Dawley; Rest

2015
Potential of the ovine brain as a model for anesthesia-induced neuroapoptosis.
    Pediatric surgery international, 2015, Volume: 31, Issue:9

    Topics: Animals; Apoptosis; Brain; Dexmedetomidine; Disease Models, Animal; Feasibility Studies; Hernias, Diaphragmatic, Congenital; Isoflurane; Sheep, Domestic

2015
Limiting the accessibility of cost-prohibitive drugs reduces overall anesthetic drug costs: a retrospective before and after analysis.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2015, Volume: 62, Issue:10

    Topics: Adult; Aged; Anesthesia Recovery Period; Anesthetics; Cost-Benefit Analysis; Desflurane; Dexmedetomidine; Drug Costs; Female; Humans; Intubation, Intratracheal; Isoflurane; Male; Middle Aged; Naloxone; Piperidines; Postoperative Nausea and Vomiting; Remifentanil; Retrospective Studies

2015
Curtailing the cost of anesthetic drugs: prudent economics or an infringement of clinical autonomy?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2015, Volume: 62, Issue:10

    Topics: Anesthetics; Dexmedetomidine; Female; Humans; Isoflurane; Male; Piperidines

2015
The real cost of care: focus on value for money, rather than price-tags.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2015, Volume: 62, Issue:10

    Topics: Anesthetics; Dexmedetomidine; Female; Humans; Isoflurane; Male; Piperidines

2015
Observational study of prolonged times to tracheal extubation.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2016, Volume: 63, Issue:1

    Topics: Anesthetics; Dexmedetomidine; Female; Humans; Isoflurane; Male; Piperidines

2016
In reply: Observational study of prolonged times to tracheal extubation.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2016, Volume: 63, Issue:1

    Topics: Anesthetics; Dexmedetomidine; Female; Humans; Isoflurane; Male; Piperidines

2016
Sevoflurane or desflurane: Which one is more expensive?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2016, Volume: 63, Issue:3

    Topics: Anesthetics; Dexmedetomidine; Female; Humans; Isoflurane; Male; Piperidines

2016
Limiting the accessibility of cost-prohibitive drugs: The story is incomplete.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2016, Volume: 63, Issue:3

    Topics: Anesthetics; Dexmedetomidine; Female; Humans; Isoflurane; Male; Piperidines

2016
In reply: Sevoflurane or desflurane: Which one is more expensive? Limiting the accessibility of cost-prohibitive drugs: The story is incomplete.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2016, Volume: 63, Issue:3

    Topics: Anesthetics; Dexmedetomidine; Female; Humans; Isoflurane; Male; Piperidines

2016
Comparison of Dexmedetomidine-Ketamine with Isoflurane for Anesthesia of Chinchillas (Chinchilla lanigera).
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2016, Volume: 55, Issue:3

    Topics: Anesthesia; Anesthesia Recovery Period; Animals; Body Weight; Chinchilla; Cross-Over Studies; Dexmedetomidine; Eating; Female; Isoflurane; Ketamine; Male; Prospective Studies

2016
α2-Adrenergic Receptor and Isoflurane Modulation of Presynaptic Ca2+ Influx and Exocytosis in Hippocampal Neurons.
    Anesthesiology, 2016, Volume: 125, Issue:3

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Inhalation; Animals; Calcium; Clonidine; Dexmedetomidine; Exocytosis; Female; Hippocampus; Isoflurane; Male; Models, Animal; Neurons; Rats; Rats, Sprague-Dawley

2016
Cardiovascular effects of dexmedetomidine, with or without MK-467, following intravenous administration in cats.
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Anesthesia, Intravenous; Anesthetics, Inhalation; Animals; Blood Pressure; Cardiovascular System; Cats; Desflurane; Dexmedetomidine; Female; Heart Rate; Isoflurane; Prospective Studies; Quinolizines; Vasoconstriction

2017
Physiological characterization of a robust survival rodent fMRI method.
    Magnetic resonance imaging, 2017, Volume: 35

    Topics: Anesthetics, Inhalation; Animals; Brain; Dexmedetomidine; Hypnotics and Sedatives; Isoflurane; Longitudinal Studies; Magnetic Resonance Imaging; Male; Models, Animal; Rats; Rats, Sprague-Dawley

2017
Dexmedetomidine Acts via the JAK2/STAT3 Pathway to Attenuate Isoflurane-Induced Neurocognitive Deficits in Senile Mice.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Animals; Cognition Disorders; Dexmedetomidine; Isoflurane; Janus Kinase 2; Mice; STAT3 Transcription Factor

2016
Global reduction of information exchange during anesthetic-induced unconsciousness.
    Brain structure & function, 2017, Volume: 222, Issue:7

    Topics: Anesthetics, Inhalation; Animals; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Image Processing, Computer-Assisted; Isoflurane; Magnetic Resonance Imaging; Male; Neural Pathways; Oxygen; Rats; Rats, Long-Evans; Reflex; Rest; Unconsciousness

2017
Pharmacokinetics of dexmedetomidine in isoflurane-anesthetized New Zealand White rabbits.
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics, Combined; Anesthetics, Inhalation; Animals; Dexmedetomidine; Female; Hypnotics and Sedatives; Infusions, Intravenous; Isoflurane; Rabbits

2017
Hemodynamic effects of low-dose atipamezole in isoflurane-anesthetized cats receiving an infusion of dexmedetomidine.
    Journal of feline medicine and surgery, 2018, Volume: 20, Issue:6

    Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Cat Diseases; Cats; Dexmedetomidine; Female; Heart Rate; Hemodynamics; Hypnotics and Sedatives; Infusions, Intravenous; Isoflurane

2018
Cardiorespiratory effects of epidural anesthesia using lidocaine with morphine or dexmedetomidine in capuchin monkeys (Sapajus sp.) undergoing bilateral tubal ligation surgery, anesthetized with isoflurane.
    Journal of medical primatology, 2017, Volume: 46, Issue:6

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Inhalation; Anesthetics, Local; Animals; Blood Pressure; Body Temperature; Cebinae; Dexmedetomidine; Female; Heart Rate; Isoflurane; Lidocaine; Lumbosacral Region; Morphine; Random Allocation; Sterilization, Tubal

2017
Anesthesia with Dexmedetomidine and Low-dose Isoflurane Increases Solute Transport via the Glymphatic Pathway in Rat Brain When Compared with High-dose Isoflurane.
    Anesthesiology, 2017, Volume: 127, Issue:6

    Topics: Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Biological Transport; Cerebrovascular Circulation; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gadolinium DTPA; Hippocampus; Hypnotics and Sedatives; Isoenzymes; Isoflurane; L-Lactate Dehydrogenase; Magnetic Resonance Imaging; Rats; Rats, Inbred F344; Signal Transduction

2017
Effects of controlled hypoxemia or hypovolemia on global and intestinal oxygenation and perfusion in isoflurane anesthetized horses receiving an alpha-2-agonist infusion.
    BMC veterinary research, 2017, Nov-28, Volume: 13, Issue:1

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dexmedetomidine; Female; Heart Rate; Horses; Hypovolemia; Hypoxia; Intestinal Mucosa; Intestines; Isoflurane; Laser-Doppler Flowmetry; Male; Oxygen; Prospective Studies; Spectrophotometry; Xylazine

2017
The clinical effects of a low dose dexmedetomidine constant rate infusion in isoflurane anesthetized cats.
    Veterinary journal (London, England : 1997), 2018, Volume: 234

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Cats; Dexmedetomidine; Female; Heart Rate; Hysterectomy; Infusions, Intravenous; Isoflurane; Ovariectomy; Prospective Studies; Respiratory Rate

2018
Comparison of desflurane and propofol at equipotent doses in combination with a constant rate infusion of dexmedetomidine on global and peripheral perfusion and oxygenation in horses.
    American journal of veterinary research, 2018, Volume: 79, Issue:5

    Topics: Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Cardiac Output; Desflurane; Dexmedetomidine; Heart Rate; Hemodynamics; Horses; Isoflurane; Ketamine; Oxygen; Perfusion; Propofol; Respiratory Physiological Phenomena; Vascular Resistance

2018
HYPERKALEMIA IN TWO JAGUARS ( PANTHERA ONCA) ANESTHETIZED WITH DEXMEDETOMIDINE, KETAMINE, AND ISOFLURANE.
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2018, Volume: 49, Issue:2

    Topics: Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Animals, Zoo; Belize; Dexmedetomidine; Female; Hyperkalemia; Hypnotics and Sedatives; Isoflurane; Ketamine; Male; Panthera

2018
Hemodynamic effects of MK-467 following intravenous administration to isoflurane-anesthetized cats concurrently receiving dexmedetomidine.
    American journal of veterinary research, 2018, Volume: 79, Issue:7

    Topics: Anesthetics, Inhalation; Animals; Arteries; Blood Pressure; Cats; Dexmedetomidine; Female; Heart Rate; Hemodynamics; Infusions, Intravenous; Isoflurane; Quinolizines; Vascular Resistance

2018
Altered stimulus representation in rat auditory cortex is not causal for loss of consciousness under general anaesthesia.
    British journal of anaesthesia, 2018, Volume: 121, Issue:3

    Topics: Acoustic Stimulation; Anesthesia, General; Anesthetics, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Auditory Cortex; Consciousness; Dexmedetomidine; Electroencephalography; Female; Hypnotics and Sedatives; Isoflurane; Propofol; Rats, Inbred ACI; Reaction Time; Reflex, Righting

2018
Dexmedetomidine low dose followed by constant rate infusion and antagonism by atipamezole in isoflurane-anesthetized cats: an echocardiographic study.
    Veterinary anaesthesia and analgesia, 2019, Volume: 46, Issue:1

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Blood Pressure; Cats; Cohort Studies; Dexmedetomidine; Echocardiography; Heart Rate; Hypnotics and Sedatives; Imidazoles; Infusions, Intravenous; Isoflurane; Male; Orchiectomy; Prospective Studies

2019
Dexmedetomidine combined with etomidate or emulsified isoflurane for induction reduced cardiopulmonary response in dogs.
    PloS one, 2018, Volume: 13, Issue:12

    Topics: Anesthetics, Inhalation; Animals; Arterial Pressure; Body Temperature; Dexmedetomidine; Dogs; Drug Interactions; Electrocardiography; Emulsions; Etomidate; Heart; Heart Rate; Isoflurane; Respiratory Physiological Phenomena; Respiratory Rate; Respiratory System; Time Factors

2018
Neuroprotective effects of dexmedetomidine against isoflurane-induced neuronal injury via glutamate regulation in neonatal rats.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Animals; Dexmedetomidine; Glutamic Acid; Injections, Intraperitoneal; Isoflurane; Male; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley

2019
Cellular stress and AMPK links metformin and diverse compounds with accelerated emergence from anesthesia and potential recovery from disorders of consciousness.
    Medical hypotheses, 2019, Volume: 124

    Topics: AMP-Activated Protein Kinases; Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Brain Mapping; Calcium; Cell Lineage; Cell Proliferation; Consciousness; Consciousness Disorders; Dexmedetomidine; Humans; Isoflurane; Ketamine; Learning; Long-Term Potentiation; Memory; Metformin; Midazolam; Models, Neurological; Nicotine; Propofol; Reactive Oxygen Species; Sevoflurane; Unconsciousness

2019
A Common Neuroendocrine Substrate for Diverse General Anesthetics and Sleep.
    Neuron, 2019, 06-05, Volume: 102, Issue:5

    Topics: Anesthesia, General; Anesthetics, General; Animals; Dexmedetomidine; Electroencephalography; Electromyography; Electrophysiological Phenomena; Hypnotics and Sedatives; Hypothalamus; Isoflurane; Ketamine; Mice; Neuroendocrine Cells; Neurons; Optogenetics; Patch-Clamp Techniques; Propofol; Proto-Oncogene Proteins c-fos; Sleep; Sleep, Slow-Wave; Supraoptic Nucleus

2019
Experimental study on the effects of isoflurane with and without remifentanil or dexmedetomidine on heart rate variability before and after nociceptive stimulation at different MAC multiples in cats.
    BMC veterinary research, 2019, Jul-24, Volume: 15, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Cats; Dexmedetomidine; Electric Stimulation; Electrocardiography; Female; Heart Rate; Isoflurane; Male; Nociception; Remifentanil

2019
Effects of injectable dexmedetomidine-ketamine-midazolam and isoflurane inhalation anesthetic protocols on ocular variables in captive black-tailed prairie dogs (
    American journal of veterinary research, 2019, Volume: 80, Issue:9

    Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Animals, Zoo; Dexmedetomidine; Eye; Intraocular Pressure; Isoflurane; Ketamine; Male; Midazolam; Sciuridae; Tears

2019
Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates.
    Investigative ophthalmology & visual science, 2019, 09-03, Volume: 60, Issue:12

    Topics: Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Dexmedetomidine; Intraocular Pressure; Isoflurane; Ketamine; Macaca mulatta; Male; Telemetry; Tonometry, Ocular; Xylazine

2019
Dexmedetomidine pretreatment attenuates isoflurane-induced neurotoxicity via inhibiting the TLR2/NF-κB signaling pathway in neonatal rats.
    Experimental and molecular pathology, 2020, Volume: 112

    Topics: Anesthetics; Animals; Animals, Newborn; Apoptosis; Dexmedetomidine; Disease Models, Animal; Hippocampus; Humans; Isoflurane; Neurons; Neuroprotective Agents; NF-kappa B; Rats; Signal Transduction; Toll-Like Receptor 2; Transcription Factor RelA

2020
Comparison of the effects of a dexmedetomidine-ketamine-midazolam anesthetic protocol versus isoflurane inhalation anesthesia on echocardiography variables and plasma cardiac troponin I concentration in black-tailed prairie dogs (
    American journal of veterinary research, 2019, Volume: 80, Issue:12

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Animals, Zoo; Dexmedetomidine; Echocardiography; Female; Heart; Isoflurane; Ketamine; Male; Midazolam; Plasma; Random Allocation; Sciuridae; Troponin I

2019
Brain interstitial fluid drainage and extracellular space affected by inhalational isoflurane: in comparison with intravenous sedative dexmedetomidine and pentobarbital sodium.
    Science China. Life sciences, 2020, Volume: 63, Issue:9

    Topics: Administration, Inhalation; Administration, Intravenous; Anesthetics, Inhalation; Animals; Biological Transport; Brain; Caudate Nucleus; Dexmedetomidine; Drainage; Extracellular Fluid; Extracellular Space; Humans; Hypnotics and Sedatives; Imidazoles; Isoflurane; Male; Norepinephrine; Pentobarbital; Prazosin; Propranolol; Rats, Sprague-Dawley; Thalamus

2020
fMRI study of olfactory processing in mice under three anesthesia protocols: Insight into the effect of ketamine on olfactory processing.
    NeuroImage, 2020, Volume: 213

    Topics: Anesthetics; Animals; Dexmedetomidine; Hypnotics and Sedatives; Isoflurane; Ketamine; Magnetic Resonance Imaging; Mice; Models, Animal; Olfactory Bulb; Olfactory Perception

2020
Anesthetic agents affect urodynamic parameters and anesthetic depth at doses necessary to facilitate preclinical testing in felines.
    Scientific reports, 2020, 07-09, Volume: 10, Issue:1

    Topics: Anesthesia Recovery Period; Anesthetics; Animals; Cats; Chloralose; Dexmedetomidine; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; Heart Rate; Isoflurane; Male; Models, Animal; Muscle Contraction; Muscle, Smooth; Pregnanediones; Pressure; Propofol; Urinary Bladder; Urodynamics

2020
Effects of isoflurane, remifentanil and dexmedetomidine on selected EEG parameters derived from a Narcotrend Monitor before and after nociceptive stimulation at different MAC multiples in cats.
    BMC veterinary research, 2020, Sep-14, Volume: 16, Issue:1

    Topics: Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Cats; Cross-Over Studies; Dexmedetomidine; Electric Stimulation; Electroencephalography; Female; Isoflurane; Male; Nociception; Prospective Studies; Remifentanil

2020
Disparate volumetric fluid shifts across cerebral tissue compartments with two different anesthetics.
    Fluids and barriers of the CNS, 2021, Jan-06, Volume: 18, Issue:1

    Topics: Anesthetics; Animals; Cerebrospinal Fluid; Cross-Over Studies; Dexmedetomidine; Female; Fluid Shifts; Glymphatic System; Gray Matter; Isoflurane; Magnetic Resonance Imaging; Rats; Rats, Sprague-Dawley

2021
Inhibition and facilitation of nociceptively evoked muscular activity by fentanyl or dexmedetomidine in isoflurane-anaesthetized pigs.
    Veterinary anaesthesia and analgesia, 2021, Volume: 48, Issue:2

    Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Dexmedetomidine; Fentanyl; Isoflurane; Swine

2021
Evaluation of the perioperative stress response from dexmedetomidine infusion alone, with butorphanol bolus or remifentanil infusion compared with ketamine and morphine infusions in isoflurane-anesthetized horses.
    Veterinary anaesthesia and analgesia, 2021, Volume: 48, Issue:3

    Topics: Anesthesia Recovery Period; Animals; Butorphanol; Dexmedetomidine; Horses; Isoflurane; Ketamine; Morphine; Prospective Studies; Remifentanil

2021
An Investigation of the Impacts of Three Anesthetic Regimens on Task-Functional Magnetic Resonance Imaging and Functional Connectivity Resting-State Functional Magnetic Resonance Imaging in Sprague Dawley and Wistar Rats.
    Brain connectivity, 2022, Volume: 12, Issue:1

    Topics: Anesthetics; Animals; Brain; Brain Mapping; Dexmedetomidine; Humans; Isoflurane; Magnetic Resonance Imaging; Rats; Rats, Sprague-Dawley; Rats, Wistar

2022
Characterization of brain-wide somatosensory BOLD fMRI in mice under dexmedetomidine/isoflurane and ketamine/xylazine.
    Scientific reports, 2021, 06-23, Volume: 11, Issue:1

    Topics: Anesthetics, Combined; Animals; Brain; Dexmedetomidine; Functional Neuroimaging; Infusions, Intravenous; Isoflurane; Ketamine; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Somatosensory Cortex; Xylazine

2021
Effects of acepromazine and dexmedetomidine, followed by propofol induction and maintenance with isoflurane anaesthesia, on the microcirculation of Beagle dogs evaluated by sidestream dark field imaging: an experimental trial.
    Veterinary anaesthesia and analgesia, 2022, Volume: 49, Issue:4

    Topics: Acepromazine; Anesthesia; Animals; Cross-Over Studies; Dexmedetomidine; Dogs; Hypnotics and Sedatives; Isoflurane; Microcirculation; Propofol

2022
THE effect of general anesthetics on genetic absence epilepsy in WAG/Rij rats.
    Neurological research, 2022, Volume: 44, Issue:11

    Topics: Anesthetics; Anesthetics, General; Anesthetics, Intravenous; Animals; Chloral Hydrate; Dexmedetomidine; Epilepsy, Absence; Isoflurane; Ketamine; Male; Pentobarbital; Rats; Urethane; Xylazine

2022
Use of dexmedetomidine repeated subcutaneous administration for balanced anaesthesia in horses.
    BMC veterinary research, 2022, Jul-11, Volume: 18, Issue:1

    Topics: Anesthesia Recovery Period; Anesthesia, General; Animals; Balanced Anesthesia; Dexmedetomidine; Dobutamine; Horses; Humans; Isoflurane

2022
Dexmedetomidine suppresses the isoflurane-induced neurological damage by upregulating Heme Oxygenase-1 via activation of the mitogen-activated protein kinase kinase 1/extracellular regulated protein kinases 1/nuclear factor erythroid 2-related factor 2 ax
    Chemico-biological interactions, 2022, Nov-01, Volume: 367

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Dexmedetomidine; Eosine Yellowish-(YS); Hematoxylin; Heme Oxygenase-1; Isoflurane; MAP Kinase Kinase 1; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rats, Wistar

2022
Comparison of two injectable anaesthetic protocols in Egyptian fruit bats (Rousettus aegyptiacus) undergoing gonadectomy.
    Scientific reports, 2022, 09-24, Volume: 12, Issue:1

    Topics: Anesthetics; Animals; Butorphanol; Castration; Chiroptera; Chlorides; Dexmedetomidine; Flumazenil; Hypnotics and Sedatives; Isoflurane; Ketamine; Midazolam; Sodium

2022
Effect of sedatives or anesthetics on the measurement of resting brain function in common marmosets.
    Cerebral cortex (New York, N.Y. : 1991), 2023, 04-25, Volume: 33, Issue:9

    Topics: Anesthetics; Animals; Brain; Callithrix; Dexmedetomidine; Hypnotics and Sedatives; Isoflurane; Midazolam; Propofol; Sevoflurane

2023
Anesthetic effects of isoflurane and fentanyl infusion in capuchin monkeys (Sapajus sp) undergoing salpingectomy or deferentectomy, previously chemically restrained with ketamine-midazolam or ketamine-dexmedetomidine.
    Journal of medical primatology, 2023, Volume: 52, Issue:3

    Topics: Anesthetics; Animals; Cebus; Dexmedetomidine; Female; Fentanyl; Isoflurane; Ketamine; Midazolam; Salpingectomy; Sapajus

2023
Dynamic 3D imaging of cerebral blood flow in awake mice using self-supervised-learning-enhanced optical coherence Doppler tomography.
    Communications biology, 2023, 03-21, Volume: 6, Issue:1

    Topics: Animals; Cerebrovascular Circulation; Cocaine; Dexmedetomidine; Imaging, Three-Dimensional; Isoflurane; Mice; Tomography, Optical Coherence; Wakefulness

2023
Evaluation of urine specific gravity as a predictor of hypotension during anaesthesia in healthy dogs premedicated with dexmedetomidine.
    Veterinary anaesthesia and analgesia, 2023, Volume: 50, Issue:3

    Topics: Anesthesia, General; Animals; Cohort Studies; Dexmedetomidine; Dog Diseases; Dogs; Hypotension; Isoflurane; Methadone; Prospective Studies; Specific Gravity

2023
Oestrous cycle affects emergence from anaesthesia with dexmedetomidine, but not propofol, isoflurane, or sevoflurane, in female rats.
    British journal of anaesthesia, 2023, Volume: 131, Issue:1

    Topics: Anesthesia, General; Animals; Dexmedetomidine; Estradiol; Female; Gases; Isoflurane; Male; Progesterone; Propofol; Rats; Rats, Sprague-Dawley; Sevoflurane

2023
Spatial and Spectral Components of the BOLD Global Signal in Rat Resting-State Functional MRI.
    Magnetic resonance in medicine, 2023, Volume: 90, Issue:6

    Topics: Animals; Brain Mapping; Dexmedetomidine; Isoflurane; Magnetic Resonance Imaging; Noise; Rats

2023