dexmedetomidine has been researched along with idazoxan in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Agbaba, D; Azzali, E; Costantino, G; Glisic, S; Laurila, JM; Nikolic, K; Perovic, V; Pieroni, M; Radi, M; Scheinin, M; Srdic-Rajic, T; Tassini, S; Veljkovic, N; Vucicevic, J | 1 |
| Chen, Y; Code, WE; Hertz, L; Zhao, Z | 1 |
| Blake, DW; Ludbrook, J; Van Leeuwen, AF | 1 |
| Clarke, RW; Eves, S; Harris, J; Peachey, JE; Stuart, E | 1 |
| Ge, H; Kallio, J; Scheinin, M | 1 |
| Ferguson, TB; Johnson, FK; Johnson, RA; Joshi, MS; Lancaster, JR; Parthasarathy, S | 1 |
| Amodeo, FS; Brummett, CM; Hong, EK; Janda, AM; Lydic, R | 1 |
| Dai, H; Ding, T; Yan, M; Yu, L; Zhang, F; Zhong, Y | 1 |
9 other study(ies) available for dexmedetomidine and idazoxan
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin.
Topics: Adrenergic alpha-Agonists; Antibiotics, Antineoplastic; Apoptosis; Doxorubicin; Drug Synergism; Humans; K562 Cells; Ligands; Molecular Structure; Oxazoles; Receptors, Adrenergic, alpha-2; Rilmenidine | 2016 |
A correlation between dexmedetomidine-induced biphasic increases in free cytosolic calcium concentration and energy metabolism in astrocytes.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Cytosol; Dantrolene; Dexmedetomidine; Dose-Response Relationship, Drug; Energy Metabolism; Hypnotics and Sedatives; Idazoxan; Mice; Muscle Relaxants, Central; Pyruvic Acid; Yohimbine | 2000 |
Dexmedetomidine and haemodynamic responses to acute central hypovolaemia in conscious rabbits.
Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alfentanil; Animals; Blood Flow Velocity; Dexmedetomidine; Drug Therapy, Combination; Female; Hemodynamics; Hemorrhage; Idazoxan; Infusions, Intravenous; Injections, Intraventricular; Pressoreceptors; Rabbits; Shock; Vasoconstriction; Vena Cava, Inferior | 2000 |
Interactions between cutaneous afferent inputs to a withdrawal reflex in the decerebrated rabbit and their control by descending and segmental systems.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Decerebrate State; Dexmedetomidine; Dizocilpine Maleate; Drug Synergism; Efferent Pathways; Electric Stimulation; Excitatory Amino Acid Antagonists; Idazoxan; Imidazoles; Muscle, Skeletal; Naloxone; Narcotic Antagonists; Neurons, Afferent; Rabbits; Reflex; Skin; Sural Nerve; Tarsus, Animal | 2002 |
Constitutive precoupling to G(i) and increased agonist potency in the alpha(2B)-adrenoceptor.
Topics: Adrenergic alpha-Antagonists; Amino Acid Motifs; Animals; Aspartic Acid; Calcium; CHO Cells; Cricetinae; Cytoplasm; Dexmedetomidine; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Idazoxan; Ligands; Mutagenesis, Site-Directed; Mutation; Pertussis Toxin; Protein Binding; Protein Conformation; Receptors, Adrenergic, alpha-2; Signal Transduction | 2003 |
Receptor-mediated activation of nitric oxide synthesis by arginine in endothelial cells.
Topics: Adrenergic alpha-Antagonists; Agmatine; Aniline Compounds; Arginine; Calcium; Calcium Channel Blockers; Cell Culture Techniques; Cells, Cultured; Culture Media, Serum-Free; Dexmedetomidine; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Estrenes; Fluorescent Dyes; Humans; Idazoxan; Imidazolines; Lipopolysaccharides; Molecular Structure; NG-Nitroarginine Methyl Ester; Nifedipine; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Pyrrolidinones; Receptors, Adrenergic, alpha-2; Second Messenger Systems; Type C Phospholipases; Umbilical Veins; Virulence Factors, Bordetella; Xanthenes; Yohimbine | 2007 |
Perineural dexmedetomidine added to ropivacaine for sciatic nerve block in rats prolongs the duration of analgesia by blocking the hyperpolarization-activated cation current.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amides; Analgesia; Anesthetics, Local; Animals; Behavior, Animal; Colforsin; Cyclic Nucleotide-Gated Cation Channels; Dexmedetomidine; Dose-Response Relationship, Drug; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Hypnotics and Sedatives; Idazoxan; Male; Nerve Block; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Prazosin; Pyrimidines; Rats; Rats, Sprague-Dawley; Ropivacaine; Sciatic Nerve | 2011 |
Dexmedetomidine protects against oxygen-glucose deprivation-induced injury through the I2 imidazoline receptor-PI3K/AKT pathway in rat C6 glioma cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Blotting, Western; Cell Survival; Dexmedetomidine; Glioma; Glucose; Hypoxia-Inducible Factor 1, alpha Subunit; Idazoxan; Imidazoles; Imidazoline Receptors; Oxygen; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Repressor Proteins; Transcription Factors; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2012 |