Compounds > dexmedetomidine
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dexmedetomidine and acetylcysteine

dexmedetomidine has been researched along with acetylcysteine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Altinbas, A; Ayhan, S; Canakci, E; Kokturk, S; Noyan, T; Tas, N1
Chen, L; Cheng, L; Lin, L; Song, Q; Zhong, W1
Chen, J; Chen, T; Chi, X; Deng, Y; Liu, P; Tan, F; Tian, J; Zheng, L1

Reviews

1 review(s) available for dexmedetomidine and acetylcysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

4 other study(ies) available for dexmedetomidine and acetylcysteine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Acute acetaminophene-induced hepatotoxicity and nephrotoxicity; therapeutic effect of dexmedetomidine.
    Bratislavske lekarske listy, 2019, Volume: 120, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Dexmedetomidine; Glutathione; Liver; Oxidative Stress; Rats

2019
Co-administration of N-acetylcysteine and dexmedetomidine plays a synergistic effect on protection of LPS-induced acute lung injury via correcting Th1/Th2/Th17 cytokines imbalance.
    Clinical and experimental pharmacology & physiology, 2020, Volume: 47, Issue:2

    Topics: Acetylcysteine; Acute Lung Injury; Adrenergic alpha-2 Receptor Agonists; Animals; Basic Helix-Loop-Helix Transcription Factors; Cytokines; Dexmedetomidine; Drug Synergism; Drug Therapy, Combination; Free Radical Scavengers; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Th1 Cells; Th17 Cells; Th2 Cells

2020
Dexmedetomidine alleviated neuropathic pain in dorsal root ganglion neurons by inhibition of anaerobic glycolysis activity and enhancement of ROS tolerance.
    Bioscience reports, 2020, 05-29, Volume: 40, Issue:5

    Topics: Acetylcysteine; Anaerobiosis; Animals; Apoptosis; Cells, Cultured; Dexmedetomidine; Disease Models, Animal; Ganglia, Spinal; Glucose; Glycolysis; Humans; Hydrogen Peroxide; Neuralgia; Neurons; Primary Cell Culture; Rats; Reactive Oxygen Species

2020