Page last updated: 2024-08-24

dexmedetomidine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

dexmedetomidine has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1
Meng, FM; Xue, FS; Zhang, JQ; Zhang, W1
Chen, Y; Gong, Q; Gong, Z; Jiang, Y; Lv, J; Wang, H; Wei, Y; Xie, Y; Zhang, X; Zhou, L1
Wang, M; Wang, N1
Hou, X; Kong, M; Ni, H; Shao, Z; Shen, Q1
Cheng, D; Li, H; Li, Y; Qu, M; Xing, F; Xing, N; Zhang, W1

Other Studies

6 other study(ies) available for dexmedetomidine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022
Dexmedetomidine protects against lung ischemia-reperfusion injury by the PI3K/Akt/HIF-1α signaling pathway.
    Journal of anesthesia, 2016, Volume: 30, Issue:5

    Topics: Animals; Chromones; Dexmedetomidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypnotics and Sedatives; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemia; Lung Injury; Male; Morpholines; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction

2016
Dexmedetomidine attenuates propofol-induce neuroapoptosis partly via the activation of the PI3k/Akt/GSK3β pathway in the hippocampus of neonatal rats.
    Environmental toxicology and pharmacology, 2017, Volume: 52

    Topics: Anesthetics, Intravenous; Animals; Animals, Newborn; Apoptosis; Chromones; Dexmedetomidine; Female; Glycogen Synthase Kinase 3 beta; Hippocampus; Male; Morpholines; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Propofol; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Thiadiazoles

2017
Dexmedetomidine suppresses sevoflurane anesthesia-induced neuroinflammation through activation of the PI3K/Akt/mTOR pathway.
    BMC anesthesiology, 2019, 07-27, Volume: 19, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Cerebral Cortex; Chromones; Cytokines; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampus; Hypnotics and Sedatives; Inflammation; Morpholines; Neuroprotective Agents; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Random Allocation; Rats, Sprague-Dawley; Sevoflurane; Signal Transduction; TOR Serine-Threonine Kinases

2019
Involvement of GPR30 in protection effect of Dexmedetomidine against myocardial ischemia/reperfusion injury in rat via AKT pathway.
    Acta biochimica Polonica, 2021, Feb-25, Volume: 68, Issue:1

    Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Survival; Cells, Cultured; Chromones; Dexmedetomidine; Disease Models, Animal; Drug Synergism; Gene Knockdown Techniques; Male; Morpholines; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Proto-Oncogene Proteins c-akt; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Transfection

2021
The Protective Mechanism of Dexmedetomidine in Regulating Atg14L-Beclin1-Vps34 Complex Against Myocardial Ischemia-Reperfusion Injury.
    Journal of cardiovascular translational research, 2021, Volume: 14, Issue:6

    Topics: Adaptor Proteins, Vesicular Transport; Animals; Autophagy; Autophagy-Related Proteins; Beclin-1; Chromones; Class III Phosphatidylinositol 3-Kinases; Dexmedetomidine; Disease Models, Animal; Morpholines; Myocytes, Cardiac; Phosphorylation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction

2021