Page last updated: 2024-09-05

dexefaroxan and desipramine

dexefaroxan has been researched along with desipramine in 1 studies

Compound Research Comparison

Studies
(dexefaroxan)
Trials
(dexefaroxan)
Recent Studies (post-2010)
(dexefaroxan)
Studies
(desipramine)
Trials
(desipramine)
Recent Studies (post-2010) (desipramine)
15045,775487414

Protein Interaction Comparison

ProteinTaxonomydexefaroxan (IC50)desipramine (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)9.18
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.35
Alpha-2A adrenergic receptorHomo sapiens (human)0.0003
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.35
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0034
Alpha-2B adrenergic receptorHomo sapiens (human)0.0003
Alpha-2C adrenergic receptorHomo sapiens (human)0.0003
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.35
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.0031
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)7.8
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 1DRattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 1FRattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 6Rattus norvegicus (Norway rat)0.35
Histamine H1 receptorRattus norvegicus (Norway rat)0.0008
Sodium-dependent serotonin transporterHomo sapiens (human)0.1961
5-hydroxytryptamine receptor 7 Rattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 5ARattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 5BRattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 3ARattus norvegicus (Norway rat)0.35
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0003
Histamine H2 receptorCavia porcellus (domestic guinea pig)3.8
Sodium-dependent dopamine transporter Homo sapiens (human)9.9
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.4035
Sodium channel protein type 5 subunit alphaHomo sapiens (human)1.52
5-hydroxytryptamine receptor 4 Rattus norvegicus (Norway rat)0.35
5-hydroxytryptamine receptor 3BRattus norvegicus (Norway rat)0.35
Solute carrier family 22 member 2Rattus norvegicus (Norway rat)10
TransporterRattus norvegicus (Norway rat)7.8

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, ME; Fahnestock, M; Francis, BM; Hajderi, E; McLaurin, J; Michalski, B; Mount, HT; Yang, J1

Other Studies

1 other study(ies) available for dexefaroxan and desipramine

ArticleYear
Reduced tissue levels of noradrenaline are associated with behavioral phenotypes of the TgCRND8 mouse model of Alzheimer's disease.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:8

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzopyrans; Brain; Brain-Derived Neurotrophic Factor; Catecholamines; Cholinesterase Inhibitors; Desipramine; Disease Models, Animal; Imidazoles; Immobility Response, Tonic; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenylcarbamates; Recognition, Psychology; Rivastigmine

2012