deuterium has been researched along with tyrosine in 182 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 99 (54.40) | 18.7374 |
| 1990's | 40 (21.98) | 18.2507 |
| 2000's | 31 (17.03) | 29.6817 |
| 2010's | 11 (6.04) | 24.3611 |
| 2020's | 1 (0.55) | 2.80 |
| Authors | Studies |
|---|---|
| Birdsall, B; Burgen, A; Feeney, J; Griffiths, DV; King, RW; Roberts, GC; Scudder, P | 1 |
| Leavis, PC; Lehrer, SS | 1 |
| Hvidt, A; Junager, F; Sorup, P | 1 |
| Moore, GR; Williams, RJ | 1 |
| Matthews, HR; Matthews, KS; Opella, SJ | 1 |
| Dobson, CM; Woodworth, RC | 1 |
| Sjöquist, B | 1 |
| Kokolis, N; Stichler, W; Ziegler, I | 1 |
| Fell, V; Hoskins, JA; Pollitt, RJ | 1 |
| Nakanishi, M; Tsuboi, M | 1 |
| Hruby, VJ; Linn, DK; Upson, DA; Yamamoto, DM | 1 |
| Cotton, RG; Danks, DM; Faull, KF; Freeman, R; Gan, I; Halpern, B; Hammond, J; Im, S | 1 |
| Burgen, AS; Feeney, J; Griffiths, DV; Roberts, GC | 1 |
| Blaskovics, ME; Byrd, DJ; Kochen, W; Lutz, P; Trefz, FK | 1 |
| Babcock, GT; Hoganson, CW | 1 |
| Evans, PD; Macfarlane, RG; Midgley, JM; Watson, DG | 1 |
| Babcock, GT; Barry, BA; el-Deeb, MK; Sandusky, PO | 1 |
| Halliday, D; Leonard, JV; Thompson, GN; Walter, JH | 1 |
| Chapman, SK; Dubois, J; Lederer, F; Mathews, FS; Reid, GA | 1 |
| Avilés, FX; Crane-Robinson, C; Turner, CH; Vendrell, J; Vilanova, M | 1 |
| White, RH; Zhou, D | 1 |
| Halkier, BA; Møller, BL; Olsen, CE | 1 |
| Nguyen, TV; Yu, PH | 1 |
| Halstrøm, J; Jørgensen, KH; Kovacs, K; Rose, K; Savoy, LA; Vuagnat, P | 1 |
| Clemens, P; Fischer, R; Grüttner, R; Heinrich, HC; Lehmann, WD | 1 |
| Kiick, DM; Phillips, RS | 1 |
| Benkovic, SJ; Chen, JT; Taira, K; Tu, CP | 1 |
| Eisenstein, L; Govindjee, R; Konno, K; Lin, SL; Nakanishi, K; Ormos, P | 1 |
| Hayashi, T; Iida, Y; Kamada, S; Naruse, H; Shimamura, M | 1 |
| Heinrich, HC; Lehmann, WD | 2 |
| Dollinger, G; Eisenstein, L; Lin, SL; Nakanishi, K; Termini, J | 1 |
| LeMaster, DM; Richards, FM | 1 |
| Boulton, AA; Davis, BA; Durden, DA | 1 |
| Morita, F; Shimizu, T; Yagi, K | 1 |
| Bleich, HE; Craig, LC; Galardy, RE; Printz, MP | 1 |
| Feher, G; Isaacson, RA; Nagel, R; Scholes, CP | 1 |
| Deslauriers, R; Smith, IC; Walter, R | 1 |
| Hsu, LL; Samorajski, T | 1 |
| Markley, JL | 1 |
| Glasel, JA; Hruby, VJ; McKelvy, JF; Spatola, AF | 1 |
| Castillo, CL; Mayer, A; Ogawa, S; Shulman, RG | 1 |
| Hunkapiller, MW; Richards, JH | 1 |
| Koehler, KM; Schmidt, PG | 1 |
| Dayan, J; DeLeo, AB; Sprinson, DB | 1 |
| Osborne, J; Steiner, RF | 1 |
| Baerlocher, K; Curtius, HC; Völlmin, JA | 3 |
| Dimicoli, JL; Helene, C | 2 |
| Caplow, M; Zeeberg, B | 1 |
| Karplus, S; Snyder, GH; Sykes, BD | 1 |
| Kirby, GW; Michael, J | 1 |
| Ogura, S; Sogami, M; Uyeda, M | 1 |
| Arrio, B; Hill, M; Parquet, C | 1 |
| Feldman, I; McGuire, R | 1 |
| Hill, RK; Kumagai, H; Mugibayashi, Y; Ogata, K; Sawada, S; Yamada, H | 1 |
| Ogawa, S; Patel, DJ; Simon, SR | 1 |
| Bradbury, AF; Burgen, AS; Feeney, J; Roberts, GC; Smyth, DG | 1 |
| Kukushkin, AK; Kuznetsov, AN | 1 |
| Greenfield, NJ; Williams, MN | 1 |
| Mori, KF | 1 |
| Fuchs, HH; Herskovits, TT | 1 |
| Cann, JR | 1 |
| Ka Luk, C | 1 |
| Go, A; Kopple, KD; Ohnishi, M | 1 |
| Bello, J | 1 |
| Herskovits, TT; Laskowski, M; Menendez, CJ | 1 |
| Herskovits, TT; Menendez, CJ | 1 |
| Crespi, HL; Daboll, HF; Katz, JJ | 1 |
| Steiner, RF; Weinryb, I | 1 |
| Föry, W; MacKenzie, RE; McCormick, DB; Wu, FY | 1 |
| Cohen, JS; Putter, I; Smith, JL; Vandenheuvel, WJ | 1 |
| Cohen, JS; Putter, I | 1 |
| Lord, RC; Yu, NT | 1 |
| Cohen, JS | 1 |
| Huc, C; Olomucki, A | 1 |
| Chaiken, IM; Cohen, JS; Feil, M | 1 |
| Parker, L; Wang, JH | 1 |
| Herskovits, TT; Sorensen, M | 1 |
| Jardetzky, O; Markley, JL; Putter, I | 1 |
| Kaplan, H; Whitaker, DR | 1 |
| Herskovits, TT | 1 |
| Bright, HJ; Porter, DJ | 1 |
| Peck, EJ; Ray, WJ | 1 |
| Martin, RB; Morlino, VJ | 1 |
| Cross, DG; Fisher, HF | 1 |
| Bundy, HF; Moore, CL | 1 |
| Moran, JF; Triggle, DJ | 1 |
| Daly, J; Guroff, G; Reifsnyder, CA | 1 |
| Abe, M; Nakanishi, M; Nosoh, Y; Tsuboi, M | 1 |
| Birdsall, B; Feeney, J; Griffiths, DV; Hammond, S; Kimber, B; King, RW; Roberts, GC; Searle, M | 1 |
| Dorgan, LJ; Schuster, SM | 1 |
| Clemens, P; Grüttner, R; Heinrich, HC; Lehmann, WD; Theobald, N | 1 |
| Bier, D; Matalon, R; Matthews, DE; Michals, K | 1 |
| Fischer, R; Heinrich, HC; Lehmann, WD; Theobald, N | 1 |
| Berger, R; Bruinvis, L; Cartigny, B; Divry, P; Duran, M; Farriaux, JP; Ketting, D; Leonard, JV; Smit, GP; Steinmann, B; van Sprang, FJ; Wadman, SK | 1 |
| Nakanishi, M; Ogasahara, K; Sugino, Y; Suzuki, M; Tsuboi, M; Yutani, K | 1 |
| Bier, DM; Clarke, JT | 1 |
| Kinsey, RA; Kintanar, A; Oldfield, E | 1 |
| Kobayashi, M; Nakanishi, M; Takasaki, C; Tamiya, N; Tsuboi, M | 1 |
| Baerlocher, K; Curtius, HC; Ettlinger, L; Fuchs-Mettler, M | 1 |
| Baba, S; Saisu, K; Tokuhisa, S; Yoshikawa, H | 1 |
| Coleman, M; Khorana, HG; Lee, CP; Liu, X; Marti, T; Patel, N; RajBhandary, UL; Rothschild, KJ; Sonar, S | 1 |
| Godoy, J; Silva, E | 1 |
| Madsen, C; Styring, S; Tommos, C; Vermaas, W | 1 |
| Nugent, JH; O'Malley, PJ; Rigby, SE | 1 |
| Burke, JF; Chapman, TE; Vogt, JA; Wagner, DA; Young, VR | 1 |
| Ator, M; Bollinger, JM; McCraken, J; Peisach, J; Robins, MJ; Salowe, S; Samano, MC; Stubbe, J | 1 |
| Brudvig, GW; Chisholm, DA; Diner, BA; Dismukes, GC; Tang, XS | 1 |
| Capeillère-Blandin, C; Lederer, F; Rouvière-Fourmy, N | 1 |
| Barry, BA | 1 |
| Basile Filho, A; Beaumier, L; Castillo, L; Chapman, TE; El-Khoury, AE; Sanchez, M; Young, VR | 1 |
| Andersson, KK; Barra, AL; Gräslund, A; Schmidt, PP; Thelander, L | 1 |
| Burzio, LA; Klug, CA; Schaefer, J; Waite, JH | 1 |
| Andrieu, JP; Bersch, B; Blanchard, L; Dolla, A; Forest, E; Gagnon, J; Guerlesquin, F; Guy, P; Jaquinod, M; Rémigy, H | 1 |
| Bartlett, K; Brock, C; Craft, AW; Daley, SE; Halliday, D; Hetherington, C; Kernahan, J; Pearson, AD; Price, L; Wyllie, RA | 1 |
| Deutsch, JC | 1 |
| Britt, RD; Force, DA; Randall, DW | 1 |
| Berthomieu, C; Boussac, A; Breton, J; Diner, BA; Hienerwadel, R | 1 |
| Hu, X; Spiro, TG | 1 |
| Bozzetti, F; Dworzak, F; Ferrari, P; Gavazzi, C; Maiorana, C | 1 |
| Connelly, GP; McIntosh, LP | 1 |
| Raleigh, DP; Wu, WJ | 1 |
| Basile-Filho, A; Beaumier, L; El-Khoury, AE; Gleason, RE; Kenneway, M; Young, VR; Yu, YM | 1 |
| Bovee-Geurts, PH; DeGrip, WJ; DeLange, F; Klaassen, CH; Liu, XM; Rothschild, KJ; Wallace-Williams, SE | 1 |
| Evans, PR; Leadlay, PF; Meier, TW; Thomä, NH | 1 |
| Ball, RO; Filler, RM; Moore, AM; Pencharz, PB; Roberts, SA | 1 |
| Britt, RD; Diner, BA; Force, DA; Randall, DW | 1 |
| Backwell, FR; Bequette, BJ; Buchan, V; Calder, AG; Crompton, LA; France, J; Kyle, CE; MaCrae, JC | 1 |
| Armstrong, A; Thomas, GJ; Wen, ZQ | 1 |
| Barazzoni, R; Tessari, P; Tiengo, A; Zanetti, M | 1 |
| Behr, J; Kannt, A; MacMillan, F; Michel, H; Prisner, T | 1 |
| Akutsu, H; Iwabuchi, T; Sekino, N; Tozawa, K; Yagi, H; Yoshida, M | 1 |
| Moynihan, DP; Parikh, S; Tonge, PJ; Xiao, G | 1 |
| De Biasi, L; Deferrari, G; Garibotto, G; Pastorino, N; Robaudo, C; Tessari, P; Vettore, M | 1 |
| Frölich, JC; Gutzki, FM; Schwedhelm, E; Tsikas, D | 1 |
| Anderson, VE; Chen, YH; Goshe, MB | 1 |
| Dove, JE; Klinman, JP; Schwartz, B | 1 |
| Chern, MK; Chou, CC; Hsiao, CD; Hsieh, CH; Kuan, IC; Liu, LF; Tam, MF; Wu, TC; Yeh, YH | 1 |
| Benevides, JM; Nakamura, K; Overman, SA; Thomas, GJ; Tsuboi, M; Ushizawa, K | 1 |
| Basran, J; Scrutton, NS; Sutcliffe, MJ | 1 |
| Buijs, J; Hagman, C; Håkansson, K; Håkansson, P; Oscarsson, S; Richter, JH | 1 |
| Arabshahi, A; Berger, E; Frey, PA; Schilling, JF; Wei, Y | 1 |
| Bar, G; Bennati, M; Ge, J; Griffin, RG; Nguyen, HH; Stubbe, JA | 1 |
| Braulio, VB; Deutz, NE; Luiking, YC; Vissers, YL; von Meyenfeldt, MF | 1 |
| Blackburn, NJ; Francisco, WA; Klinman, JP | 1 |
| Oikawa, H | 1 |
| Gaffney, BJ; Katsir, LJ; Seavy, M; Wu, F | 1 |
| Harry, D; Mani, AR; Moore, KP; Ollosson, R; Orie, NN; Pannala, AS; Rice-Evans, CA | 1 |
| Ito, Y; Laue, ED; Nakayama, H; Nietlispach, D; Rajesh, S; Shibata, T; Takio, K | 1 |
| Brenna, E; Fronza, G; Fuganti, C; Pinciroli, M | 1 |
| CHRISTOMANOS, AA; GARDIKI, V | 1 |
| Kazazić, S; Klasinc, L; Rozman, M; Srzić, D | 1 |
| Fitzpatrick, PF; Sobrado, P | 1 |
| Go, EP; Harris, K; Shen, Z; Siuzdak, G | 1 |
| Albright, R; Bigelow, M; Boirie, Y; Nair, KS | 1 |
| Badaloo, A; Forrester, T; Heird, WC; Jahoor, F; Reid, M | 1 |
| Barry, BA; Bender, SL; Sacksteder, CA | 1 |
| Hewlins, MJ; John, RA; Markova, M; Peneff, C; Schirmer, T | 1 |
| Benoist, JF; Bourcier, S; Clerc, F; Hoppilliard, Y; Rigal, O; Taghi, M | 1 |
| Christiansen, JS; Gravholt, CH; Møller, N; Riis, AL | 1 |
| Barazzoni, R; Cecchet, D; Kiwanuka, E; Orlando, R; Tessari, P; Vettore, M; Zanetti, M | 1 |
| Gupta, A; Matsui, K; Mukherjee, A; Roth, JP | 1 |
| Gennis, RB; Lugtenburg, J; Maeda, A; Morgan, JE; Vakkasoglu, AS | 1 |
| Lenferink, A; Otto, C; van Manen, HJ | 1 |
| Julian, RR; Ly, T | 1 |
| Cook, PF; Lin, Y; West, AH | 1 |
| Boirie, Y; de Roos, AL; Fauquant, J; Gijsen, AP; Kies, AK; Koopman, R; Lemosquet, S; Saris, WH; van Loon, LJ | 1 |
| Baldini, L; Casnati, A; Kalenius, E; Neitola, R; Sansone, F; Torvinen, M; Ungaro, R; Vainiotalo, P | 1 |
| Bittl, R; Kern, J; Kessen, S; Teutloff, C; Zouni, A | 1 |
| Kulmacz, RJ; Lü, JM; Tsai, AL; van der Donk, WA; Wu, G | 1 |
| de Lange, A; Gijsen, AP; Groen, B; Pennings, B; Senden, JM; van Loon, LJ; Zorenc, AH | 1 |
| Hamley, IW; Rodríguez-Pérez, JC; Squires, AM | 1 |
| Ellis, HR; Eser, BE; Fitzpatrick, PF; Krzyaniak, MD; McCracken, J | 1 |
| Barnett, DW; Curley, RW; Refaei, MS | 1 |
| Makins, C; Mu, C; Walsby, CJ; Whitelaw, DA; Wolthers, KR | 1 |
| Mani, AR; Moore, KP; Moreno, JC; Visser, TJ | 1 |
| Chen, L; Feng, C; Li, W; Miao, Y; Zheng, H | 1 |
| Akabayov, SR; Anglister, J; Arshava, B; Kessler, N; Moseri, A; Naider, F; Srivastava, G | 1 |
| Boon-Spijker, M; Ebberink, EHTM; Freato, N; Meijer, AB; Przeradzka, MA; van den Biggelaar, M; van der Zwaan, C; van Galen, J | 1 |
4 trial(s) available for deuterium and tyrosine
| Article | Year |
|---|---|
Phenylalanine and tyrosine metabolism in neonates receiving parenteral nutrition differing in pattern of amino acids.
Topics: Amino Acids; Carbon Isotopes; Deuterium; Female; Humans; Hydroxylation; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Kinetics; Male; Nutritional Requirements; Oxidation-Reduction; Parenteral Nutrition, Total; Phenylalanine; Tyrosine | 1998 |
Impairment of phenylalanine conversion to tyrosine in end-stage renal disease causing tyrosine deficiency.
Topics: Adult; Aged; Deuterium; Humans; Hydrocortisone; Insulin; Insulin-Like Growth Factor I; Kidney Failure, Chronic; Middle Aged; Nitrogen Isotopes; Phenylalanine; Tyrosine | 2004 |
Protein metabolism in Turner syndrome and the impact of hormone replacement therapy.
Topics: Adult; Body Composition; Calorimetry, Indirect; Cross-Over Studies; Deuterium; Energy Metabolism; Estrogens; Female; Hormone Replacement Therapy; Humans; Muscle, Skeletal; Nitrogen Isotopes; Phenylalanine; Progesterone; Proteins; Turner Syndrome; Tyrosine; Young Adult | 2007 |
Amino acid absorption and subsequent muscle protein accretion following graded intakes of whey protein in elderly men.
Topics: Aged; Aging; Algorithms; Amino Acids; Blood Glucose; Carbon Isotopes; Deuterium; Digestion; Humans; Insulin; Intestinal Absorption; Kinetics; Male; Milk Proteins; Muscle Proteins; Oxidation-Reduction; Phenylalanine; Postprandial Period; Quadriceps Muscle; Tyrosine; Whey Proteins | 2012 |
178 other study(ies) available for deuterium and tyrosine
| Article | Year |
|---|---|
1H nuclear magnetic resonance studies of the tyrosine residues of selectively deuterated Lactobacillus casei dihydrofolate reductase.
Topics: Binding Sites; Deuterium; Folic Acid Antagonists; Lacticaseibacillus casei; Ligands; Magnetic Resonance Spectroscopy; Protein Conformation; Tetrahydrofolate Dehydrogenase; Tyrosine | 1977 |
Intrinsic fluorescence studies on troponin C.
Topics: Binding Sites; Calcium; Citrates; Deuterium; Hydrogen-Ion Concentration; Magnesium; Muscle Proteins; Protein Conformation; Spectrometry, Fluorescence; Troponin; Tyrosine | 1978 |
Physicochemical studies of a branched polypeptide antigen: poly(L-Tyr,L-Glu)-poly(DL-Ala)--poly(L-Lys).
Topics: Alanine; Antigens; Deuterium; Epitopes; Glutamates; Hydrogen; Hydrogen-Ion Concentration; Isoelectric Point; Lysine; Peptides; Protein Conformation; Spectrophotometry, Infrared; Structure-Activity Relationship; Tyrosine; Viscosity | 1977 |
Assignment of aromatic amino acid PMR resonances of horse ferrocytochrome C.
Topics: Animals; Chemical Phenomena; Chemistry; Cytochrome c Group; Deuterium; Horses; Magnetic Resonance Spectroscopy; Protons; Tryptophan; Tyrosine | 1975 |
Selectively deuterated amino acid analogues. Synthesis, incorporation into proteins and NMR properties.
Topics: Amino Acids; Bacterial Proteins; Chemical Phenomena; Chemistry; Deuterium; Enzyme Repression; Escherichia coli; Histidine; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Tryptophan; Tyrosine | 1977 |
Selective substitution of 2H and 3H into aromatic amino acids catalyzed by Raney nickel.
Topics: Chemical Phenomena; Chemistry; Deuterium; Magnetic Resonance Spectroscopy; Nickel; Phenylalanine; Tritium; Tryptophan; Tyrosine | 1979 |
Analysis of tyrosine and deuterium labelled tyrosine in tissues and body fluids.
Topics: Animals; Deuterium; Male; Mass Spectrometry; Methylation; Rats; Tyrosine | 1979 |
In vivo metabolism of deutero-L-phenylalanine and deutero-L-tyrosine in normal and in various tumor-bearing rats.
Topics: Animals; Biopterins; Deuterium; Female; Hydroxylation; Kinetics; Liver Neoplasms, Experimental; Male; Phenylalanine; Phenylalanine Hydroxylase; Rats; Sarcoma, Experimental; Tyrosine | 1977 |
The labelling of urinary acids after oral doses of deuterated L-phenylalanine and L-tyrosine in normal subjects. Quantitative studies with implications for the deuterated phenylalanine load test in phenylketonuria.
Topics: Acids; Adult; Amino Acids; Deuterium; Female; Humans; Male; Phenylalanine; Phenylketonurias; Time Factors; Tyrosine | 1978 |
Measurement of hydrogen exchange at the tyrosine residues in ribonuclease A by stopped-flow and ultraviolet spectroscopy.
Topics: Animals; Cattle; Deuterium; Hydrogen; Kinetics; Pancreas; Ribonucleases; Spectrophotometry, Ultraviolet; Tyrosine | 1978 |
Synthesis of specific deuterium labeled tyrosine and phenylalanine derivatives and their use in the total synthesis of [8-arginine]vasopressin derivatives: The separation of diastereomeric [8-arginine]vasopressin derivatives by partition chromatography1,2
Topics: Arginine Vasopressin; Chromatography; Deuterium; Isotope Labeling; Phenylalanine; Stereoisomerism; Tyrosine; Vasopressins | 1977 |
Metabolic studies on two patients with nonhepatic tyrosinemia using deuterated tyrosine loads.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adult; Amino Acid Metabolism, Inborn Errors; Child; Deuterium; Female; Humans; Hydroxy Acids; Lactates; Male; Phenols; Phenylacetates; Phenylpyruvic Acids; Tyrosine | 1977 |
Preparation of selectively deuterated aromatic amino acids for use in 1H NMR studies of proteins.
Topics: Deuterium; Histidine; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Tryptophan; Tyrosine | 1976 |
Determination of deuterium-labeled phenylalanine and tyrosine in human plasma with high pressure liquid chromatography and mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Deuterium; Humans; Isotope Labeling; Mass Spectrometry; Phenylalanine; Phenylthiohydantoin; Tyrosine | 1976 |
Protein-tyrosyl radical interactions in photosystem II studied by electron spin resonance and electron nuclear double resonance spectroscopy: comparison with ribonucleotide reductase and in vitro tyrosine.
Topics: Cyanobacteria; Deuterium; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Molecular Structure; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Ribonucleotide Reductases; Spectrum Analysis; Tyrosine | 1992 |
Identification and quantitation of phenylalanine, tyrosine and dihydroxyphenylalanine in the thoracic nervous system of the locust, Schistocerca gregaria, by gas chromatography-negative-ion chemical ionisation mass spectrometry.
Topics: Animals; Deuterium; Dihydroxyphenylalanine; Female; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Grasshoppers; Male; Nervous System; Phenylalanine; Propanols; Thorax; Tyrosine | 1990 |
Tyrosine radicals in photosystem II and related model compounds. Characterization by isotopic labeling and EPR spectroscopy.
Topics: Cyanobacteria; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Models, Molecular; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Radioisotope Dilution Technique; Tritium; Tyrosine | 1990 |
In vivo enzyme activity in inborn errors of metabolism.
Topics: Adult; Bicarbonates; Carbon Isotopes; Child; Child, Preschool; Deuterium; Female; Humans; Hydroxylation; Isotope Labeling; Leucine; Male; Malonates; Maple Syrup Urine Disease; Metabolism, Inborn Errors; Methylmalonic Acid; Oxidation-Reduction; Phenylalanine; Phenylketonurias; Propionates; Radioisotope Dilution Technique; Reference Values; Tyrosine | 1990 |
Substitution of Tyr254 with Phe at the active site of flavocytochrome b2: consequences on catalysis of lactate dehydrogenation.
Topics: Binding Sites; Catalysis; Deuterium; Fungal Proteins; Hydroxybutyrates; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Lactates; Lactic Acid; Models, Molecular; Phenylalanine; Protein Conformation; Pyruvates; Saccharomyces cerevisiae; Tyrosine | 1990 |
1H-n.m.r. studies of the isolated activation segment from pig procarboxypeptidase A.
Topics: Animals; Carboxypeptidases; Carboxypeptidases A; Chemical Phenomena; Chemistry; Deuterium; Enzyme Activation; Enzyme Precursors; Histidine; Hot Temperature; Hydrogen-Ion Concentration; Iodine; Kinetics; Magnetic Resonance Spectroscopy; Osmolar Concentration; Pancreas; Peptide Fragments; Protein Conformation; Protein Denaturation; Swine; Tritium; Tyrosine; Urea | 1990 |
Biosynthesis of caldariellaquinone in Sulfolobus spp.
Topics: Carbon Isotopes; Deuterium; Gram-Negative Chemolithotrophic Bacteria; Isotope Labeling; Mass Spectrometry; Oxygen Isotopes; Quinones; Tyrosine | 1989 |
The biosynthesis of cyanogenic glucosides in higher plants. The (E)- and (Z)-isomers of p-hydroxyphenylacetaldehyde oxime as intermediates in the biosynthesis of dhurrin in Sorghum bicolor (L.) Moench.
Topics: Carbon Radioisotopes; Chromatography, High Pressure Liquid; Deuterium; Glucosides; Glycosides; Isomerism; Mass Spectrometry; Microsomes; Nitriles; Oximes; Plants; Radioisotope Dilution Technique; Tyrosine | 1989 |
Deuterium isotope effect in the transamination of p-tyrosine by rat liver tyrosine transaminase.
Topics: Animals; Chemical Phenomena; Chemistry; Deuterium; Ketoglutaric Acids; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Tyrosine; Tyrosine Transaminase | 1985 |
The preparation of porcine (Tyr-A14-2H) insulin and its characterization by mass spectrometry.
Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Deuterium; Insulin; Iodine Radioisotopes; Mass Spectrometry; Palladium; Tyrosine | 1988 |
Metabolic conversion of L-[U-14C]phenylalanine to respiratory 14CO2 in healthy subjects, phenylketonuria heterozygotes and classic phenylketonurics.
Topics: Breath Tests; Carbon Dioxide; Carbon Radioisotopes; Deuterium; Heterozygote; Humans; Hydroxylation; Phenylalanine; Phenylketonurias; Tyrosine | 1986 |
Mechanistic deductions from kinetic isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Erwinia herbicola and Citrobacter freundii tyrosine phenol-lyase.
Topics: Alanine; Binding, Competitive; Citrobacter; Cysteine; Deuterium; Erwinia; Hydrogen-Ion Concentration; Kinetics; Lyases; Phenylalanine; Pyridoxal Phosphate; Tyrosine; Tyrosine Phenol-Lyase | 1988 |
Probing the functional role of phenylalanine-31 of Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
Topics: Amino Acids; Binding Sites; Deuterium; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Mutation; NADP; Phenylalanine; Plasmids; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tyrosine; Valine | 1987 |
Deprotonation of tyrosines in bacteriorhodopsin as studied by Fourier transform infrared spectroscopy with deuterium and nitrate labeling.
Topics: Bacteriorhodopsins; Deuterium; Fourier Analysis; Halobacterium; Methane; Spectrophotometry, Infrared; Tetranitromethane; Tyrosine | 1987 |
Sensitive determination of tyrosine metabolites, p-hydroxyphenylacetic acid, 4-hydroxy-3-methoxyphenyl-acetic acid and 4-hydroxy-3-methoxymandelic acid, by gas chromatography-negative-ion chemical-ionization mass spectrometry. Application to a stable isot
Topics: Chromatography, High Pressure Liquid; Deuterium; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Humans; Phenylacetates; Time Factors; Tyrosine; Vanilmandelic Acid | 1986 |
The NIH-shift in the in vivo hydroxylation of ring-deuterated L-phenylalanine in man.
Topics: Adult; Biotransformation; Deuterium; Genetic Carrier Screening; Humans; Hydroxylation; Isotope Labeling; Phenylalanine; Phenylketonurias; Tyrosine | 1986 |
Fourier transform infrared difference spectroscopy of bacteriorhodopsin and its photoproducts regenerated with deuterated tyrosine.
Topics: Bacteriorhodopsins; Deuterium; Fourier Analysis; Halobacterium; Photolysis; Protein Conformation; Spectrophotometry, Infrared; Tyrosine | 1986 |
1H-15N heteronuclear NMR studies of Escherichia coli thioredoxin in samples isotopically labeled by residue type.
Topics: Bacterial Proteins; Crosses, Genetic; Deuterium; Escherichia coli; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Thioredoxins; Tyrosine | 1985 |
Oral versus intravenous L-phenylalanine loading compared by simultaneous application of L-[2H5] and L-[15N]phenylalanine.
Topics: Administration, Oral; Adult; Deuterium; Female; Humans; Infusions, Parenteral; Kinetics; Male; Nitrogen Isotopes; Phenylalanine; Tyrosine | 1985 |
Qualitative and quantitative mass spectrometry of some noncatecholic biogenic amines and related compounds as their dansyl derivatives.
Topics: Biogenic Amines; Chromatography, Thin Layer; Dansyl Compounds; Deuterium; Enterococcus faecalis; Evaluation Studies as Topic; Mass Spectrometry; Methods; Microchemistry; Phenethylamines; Phenols; Structure-Activity Relationship; Tyramine; Tyrosine | 1974 |
Interaction of heavy meromyosin with substrate. IV. Studies on the tyrosine and tryptophan residues by solvent perturbation method.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Chemical Phenomena; Chemistry; Deuterium; Esters; Glycerol; Glycols; Methods; Muscle Proteins; Optical Rotatory Dispersion; Phenylalanine; Solvents; Spectrophotometry; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays | 1971 |
Conformational studies of angiotensin peptides in aqueous solution by proton magnetic resonance.
Topics: Angiotensin II; Deuterium; Half-Life; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Peptides; Protein Conformation; Temperature; Tyrosine; Valine | 1973 |
Electron nuclear double resonance (ENDOR) investigation on myoglobin and hemoglobin.
Topics: Binding Sites; Deuterium; Electron Spin Resonance Spectroscopy; Glutamates; Hemoglobins; Hemoglobins, Abnormal; Histidine; Humans; Iron; Iron Radioisotopes; Mathematics; Methemoglobin; Models, Structural; Myoglobin; New York; Nitrogen Isotopes; Nuclear Physics; Protein Binding; Protein Conformation; Tyrosine; Valine; Wisconsin | 1973 |
The conformation of oxytocin in dimethylsulfoxide as revealed by carbon-13 spin-lattice relaxation times.
Topics: Carbon Isotopes; Computers; Deuterium; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Fourier Analysis; Glucosamine; Isoleucine; Leucine; Molecular Conformation; Oxytocin; Time Factors; Tyrosine | 1974 |
Irradiation of mouse brain: effects on incorporation of tyrosine-14C into catecholamines in vivo and on uptake of NE-14C by brain slices in vitro.
Topics: Animals; Brain; Brain Chemistry; Carbon Radioisotopes; Catecholamines; Deuterium; Female; Half-Life; Mice; Radiation Effects; Time Factors; Tyrosine | 1974 |
High-resolution proton magnetic resonance studies of two trypsin inhibitors: soybean trypsin inhibitor (Kunitz) and ovomucoid (hen egg white).
Topics: Binding Sites; Computers; Deuterium; Egg Proteins; Egg White; Glycine; Glycine max; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mathematics; Phenylalanine; Protein Binding; Protein Conformation; Trypsin Inhibitors; Tyrosine | 1973 |
Deuteron magnetic resonance studies of neurohypophysial hormones.
Topics: Deuterium; Histocytochemistry; Magnetic Resonance Spectroscopy; Mathematics; Microscopy, Electron; Molecular Conformation; Oxytocin; Pituitary Gland, Posterior; Tyrosine | 1973 |
High-resolution proton NMR studies of low affinity hemoglobins.
Topics: Asparagine; Aspartic Acid; Binding Sites; Carbon Isotopes; Deuterium; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen-Ion Concentration; Iron; Japan; Kansas; Magnetic Resonance Spectroscopy; Methylation; Mutation; Oxyhemoglobins; Protein Binding; Protein Conformation; Threonine; Tyrosine | 1973 |
Studies on the catalytic mechanism of pepsin using a new synthetic substrate.
Topics: Acetophenones; Animals; Azo Compounds; Bromine; Catalysis; Deuterium; Endopeptidases; Fluoroacetates; Glycine; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Pepsin A; Phenylalanine; Protein Binding; Structure-Activity Relationship; Swine; Tryptophan; Tyrosine | 1972 |
NMR study of the modified base resonances of tRNA tyr- coli .
Topics: Chemical Phenomena; Chemistry; Deuterium; Escherichia coli; Guanosine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Nucleosides; Protons; RNA, Transfer; Spectrum Analysis; Tyrosine | 1973 |
Purification and kinetics of tyrosine-sensitive 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthetase from Salmonella.
Topics: Aldehyde-Lyases; Chromatography; Chromatography, DEAE-Cellulose; Computers; Deuterium; Erythritol; Heptoses; Isoenzymes; Kinetics; Mathematics; Models, Chemical; Molecular Weight; Oxygen Isotopes; Phosphates; Phosphoenolpyruvate; Phosphorus Isotopes; Protein Binding; Salmonella typhimurium; Tetroses; Tritium; Tyrosine | 1973 |
The self-association of chymotrypsinogen.
Topics: Chemical Phenomena; Chemistry; Chymotrypsinogen; Deuterium; Hydrogen-Ion Concentration; Macromolecular Substances; Mathematics; Methane; Molecular Weight; Nitro Compounds; Optical Rotation; Osmolar Concentration; Scattering, Radiation; Temperature; Tyrosine; Ultracentrifugation | 1972 |
Pathogenesis of phenylketonuria: inhibition of DOPA and catecholamine synthesis in patients with phenylketonuria.
Topics: Amino Acid Metabolism, Inborn Errors; Catecholamines; Catechols; Child; Child, Preschool; Deuterium; Dihydroxyphenylalanine; Dopamine; Glycols; Homovanillic Acid; Humans; Mass Spectrometry; Phenylalanine; Phenylketonurias; Tyrosine; Vanilmandelic Acid | 1972 |
Interaction of oligopeptides containing aromatic amino acids with nucleic acids. Fluorescence and proton magnetic resonance studies.
Topics: Adenine Nucleotides; Animals; Cattle; Deuterium; DNA; Magnetic Resonance Spectroscopy; Mathematics; Oligopeptides; Polynucleotides; Spectrometry, Fluorescence; Thymus Gland; Tryptophan; Tyrosine | 1972 |
Transition state charge distribution in reactions of an acetyltyrosylchymotrypsin intermediate.
Topics: Acetates; Amines; Ammonia; Aniline Compounds; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Chlorine; Chymotrypsin; Deuterium; Ethylamines; Fluorine; Formates; Hydrazines; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Methyl Ethers; Semicarbazones; Structure-Activity Relationship; Tyrosine | 1973 |
A nuclear magnetic resonance study of bovine pancreatic trypsin inhibitor. Tyrosine titrations and backbone NH groups.
Topics: Amines; Animals; Cattle; Chemical Phenomena; Chemistry; Deuterium; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mercaptoethanol; Pancreas; Protein Denaturation; Protons; Trypsin Inhibitors; Tyrosine; Urea | 1973 |
Stereoselective -labelling of aromatic amino-acids with deuterium and tritium.
Topics: Amines; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry; Cinnamates; Deuterium; Hydroxylation; Isotope Labeling; Methods; Phenylalanine; Tritium; Tyrosine | 1973 |
Conformational changes induced by the interaction of sodium dodecyl sulfate with bovine plasma albumin.
Topics: Acetates; Animals; Cattle; Deuterium; Fatty Acids; Hydrogen-Ion Concentration; Potassium Chloride; Protein Binding; Protein Conformation; Serum Albumin, Bovine; Sodium; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Spectrophotometry; Tryptophan; Tyrosine | 1973 |
Luminescence of the tryptophan and tyrosine residues of trypsin.
Topics: Amino Acid Sequence; Binding Sites; Binding, Competitive; Deuterium; Fluorescence; Iodine Radioisotopes; Luminescent Measurements; Protein Conformation; Protein Denaturation; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature; Thermodynamics; Time Factors; Trypsin; Trypsin Inhibitors; Tryptophan; Tyrosine; Urea | 1973 |
The quenching of tyrosine and tryptophan fluorescence by H20 and D20.
Topics: Deuterium; Mathematics; Quantum Theory; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine; Water | 1973 |
Study of metabolic pathways in vivo using stable isotopes.
Topics: Benzoates; Chromatography, Gas; Deuterium; Hippurates; Humans; Isotope Labeling; Leucine; Mass Spectrometry; Metabolism, Inborn Errors; Methods; Tyrosine | 1973 |
Stereochemistry of ammonia elimination from L-tyrosine with L-phenylalanine ammonia-lyase.
Topics: Ammonia-Lyases; Binding Sites; Chymotrypsin; Deuterium; Magnetic Resonance Spectroscopy; Mitosporic Fungi; Optical Rotation; Phenylalanine; Stereoisomerism; Tritium; Tyrosine | 1973 |
Proton magnetic resonance study of the switch between the two quaternary structures in high-affinity hemoglobins in the deoxy state.
Topics: Adult; Arginine; Borates; Buffers; Chemical Phenomena; Chemistry; Deuterium; Hemoglobins; Histidine; Humans; Hydrogen-Ion Concentration; Inositol; Ligands; Macromolecular Substances; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Phosphates; Protein Binding; Protein Conformation; Protons; Succinimides; Taurine; Tromethamine; Tyrosine | 1974 |
Unequivocal assignments of NH proton magnetic resonance bands in oxytocin using 2H- and 15N-substituted molecules.
Topics: Animals; Biological Assay; Chromatography, Gel; Chromatography, Thin Layer; Crystallization; Deuterium; Female; Isoleucine; Isotope Labeling; Leucine; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Oxytocin; Protein Conformation; Rats; Structure-Activity Relationship; Tyrosine; Uterus | 1974 |
Interactions of aromatic residues of proteins with nucleic acid. II. Proton magnetic resonance studies of the binding of tyramine and tyrosine-containing peptides to poly(adenylic acid) and deoxyribonucleic acid.
Topics: Adenine Nucleotides; Amines; Animals; Cattle; Chemical Phenomena; Chemistry; Cold Temperature; Deuterium; DNA; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Methyl Ethers; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligopeptides; Osmolar Concentration; Polynucleotides; Protein Binding; Protons; Sodium Chloride; Structure-Activity Relationship; Thymus Gland; Tyramine; Tyrosine | 1974 |
[On possible physical mechanism of thermoluminescence of certain aromatic amino acids and proteins].
Topics: Amino Acids; Chemical Phenomena; Chemistry, Physical; Cold Temperature; Deuterium; Hot Temperature; Kinetics; Luminescence; Pepsin A; Proteins; Trypsin; Tryptophan; Tyrosine; Ultraviolet Rays | 1966 |
The use of deuterated phenylalanine for the elucidation of the phenylalanine-tyrosine metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Chromatography, Gas; Deuterium; Humans; Hydroxylation; Infant; Lactates; Mass Spectrometry; Methods; Phenols; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1972 |
Proton magnetic resonance studies of human hemoglobin. Histidine titrations.
Topics: Carboxypeptidases; Chromatography, Thin Layer; Deuterium; Hemoglobins; Histidine; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methemoglobin; Oxygen; Tyrosine | 1972 |
Location of tryptophyl and tyrosyl residues in human chorionic gonadotropin.
Topics: Chorionic Gonadotropin; Deuterium; Glycols; Humans; Mercaptoethanol; Protein Conformation; Spectrophotometry; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays; Urea | 1972 |
Solvent perturbation of the tyrosyl and tryptophyl residues in subtilisin BPN'.
Topics: Chemical Phenomena; Chemistry; Circular Dichroism; Deuterium; Dimethyl Sulfoxide; Endopeptidases; Glycerol; Glycols; Optical Rotatory Dispersion; Protein Conformation; Solvents; Spectrophotometry; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays; X-Ray Diffraction | 1972 |
Cooperative interaction of aliphatic acids with ribonuclease A.
Topics: Acetates; Amides; Buffers; Butyrates; Chemical Phenomena; Chemistry; Circular Dichroism; Deuterium; Dialysis; Dioxins; Electrophoresis; Hydrogen-Ion Concentration; Mathematics; Optical Rotatory Dispersion; Osmolar Concentration; Propionates; Protein Binding; Protein Conformation; Protein Denaturation; Ribonucleases; Spectrophotometry; Temperature; Thermodynamics; Tyrosine; Ultraviolet Rays; Urea; Valerates | 1971 |
Study of the nature of the metal-binding sites and estimate of the distance between the metal-binding sites in transferrin using trivalent lanthanide ions as fluorescent probes.
Topics: Binding Sites; Chlorides; Copper; Deuterium; Energy Transfer; Erbium; Europium; Fluorometry; Holmium; Humans; Iron; Kinetics; Lanthanum; Mathematics; Neodymium; Praseodymium; Protein Binding; Spectrophotometry; Terbium; Transferrin; Tyrosine; Ultraviolet Rays; Water | 1971 |
Conformations of cyclic peptides. IV. Nuclear magnetic resonance studies of cyclo-pentaglycyl-L-leucyl and cyclo-diglycyl-L-histidyldiglycyl-L-tyrosyl.
Topics: Deuterium; Dimethyl Sulfoxide; Fluoroacetates; Glycine; Histidine; Hot Temperature; Leucine; Magnetic Resonance Spectroscopy; Peptides; Solvents; Tyrosine | 1969 |
The thermal perturbation method for the estimation of exposed tyrosines of proteins. I. Ribonuclease in aqueous glycol, glycerol, and enaturants.
Topics: Animals; Bromides; Cattle; Chemical Phenomena; Chemistry; Chlorides; Deuterium; Glycerol; Glycols; Guanidines; Lithium; Methods; Pancreas; Protein Denaturation; Proteins; Ribonucleases; Solvents; Spectrophotometry; Temperature; Tyrosine; Water | 1969 |
Studies of the location of the tyrosyl residues in insulin. I.
Topics: Amino Acid Sequence; Animals; Cattle; Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Glycerol; Glycols; Hydrogen-Ion Concentration; Insulin; Methanol; Optical Rotatory Dispersion; Oxides; Peptides; Protein Denaturation; Silver; Spectrophotometry; Sucrose; Trypsin; Tyrosine; Ultraviolet Rays; Urea; Zinc | 1969 |
Studies of the location of the tyrosyl residues in insulin. II.
Topics: Amino Acid Sequence; Animals; Cattle; Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Glycerol; Glycols; Hydrogen-Ion Concentration; Insulin; Methanol; Optical Rotatory Dispersion; Oxides; Peptides; Phenylalanine; Spectrophotometry; Spectrum Analysis; Sucrose; Trypsin; Trypsin Inhibitors; Tyrosine; Ultraviolet Rays; Zinc | 1969 |
The biosynthesis of isotope hybrid proteins for high resolution nuclear magnetic resonance studies by incorporation of [1H]amino acids into fully deuterated algae.
Topics: Alanine; Amino Acids; Deuterium; Eukaryota; Hydrogen; Leucine; Magnetic Resonance Spectroscopy; Methionine; Phenylalanine; Protein Biosynthesis; Tyrosine | 1970 |
Luminescence of the tryptophan and tyrosine residues of papain in solution.
Topics: Cold Temperature; Cysteine; Deuterium; Fluorescence; Glucose; Glycols; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Papain; Tryptophan; Tyrosine | 1970 |
Flavinyl peptides. 3. Studies of intramolecular interactions in flavinyl aromatic amino acids by proton magnetic resonance.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Esters; Flavins; Magnetic Resonance Spectroscopy; Models, Structural; Peptides; Phenylalanine; Temperature; Tryptophan; Tyrosine | 1970 |
Gas-liquid chromatography and mass spectrometry of deuterium-containing amino acids as their trimethylsilyl derivatives.
Topics: Alanine; Amino Acids; Asparagine; Chromatography, Gas; Deuterium; Glycine; Leucine; Methionine; Proline; Silicon; Spectrum Analysis; Tyrosine; Valine | 1970 |
The isolation of deuterated amino acids.
Topics: Amino Acids; Aspartic Acid; Autoanalysis; Chromatography, Ion Exchange; Deuterium; Glutamates; Magnetic Resonance Spectroscopy; Methods; Protein Hydrolysates; Tyrosine | 1970 |
Laser-excited Raman spectroscopy of biomolecules. II. Native ribonuclease and alpha-chymotrypsin.
Topics: Amides; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Cystine; Deuterium; Glutamates; Histidine; Hydrogen-Ion Concentration; Lasers; Muramidase; Peptides; Phenylalanine; Protein Denaturation; Ribonucleases; Spectrum Analysis; Sulfides; Tryptophan; Tyrosine | 1970 |
Proton magnetic resonance studies of oligopeptides containing aromatic residues.
Topics: Deuterium; Dimethyl Sulfoxide; Dipeptides; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Peptides; Phenylalanine; Protein Denaturation; Proteins; Protons; Tryptophan; Tyrosine | 1971 |
Essential histidyl residues of octopine dehydrogenase.
Topics: Animals; Carbonates; Cysteine; Deuterium; Dicarboxylic Acids; Guanidines; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; L-Lactate Dehydrogenase; Mollusca; Muscles; Oxidoreductases; Spectrophotometry; Tyrosine | 1971 |
Proton magnetic resonance studies of the tyrosine residues of staphylococcal nuclease using [3,5- 2 H 2 ] tyrosine.
Topics: Calcium; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Ion Exchange; Chromatography, Thin Layer; Deoxyribonucleases; Deoxyribonucleotides; Deuterium; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methods; Nitro Compounds; Polysaccharides; Protons; Staphylococcus; Thymine Nucleotides; Tyrosine | 1971 |
On the mechanism of action at the acylation step of the alpha-chymotrypsin-catalyzed hydrolysis of anilides.
Topics: Anilides; Chemical Phenomena; Chemistry; Chymotrypsin; Deuterium; Hydrogen-Ion Concentration; Kinetics; Tyrosine | 1968 |
Studies of the location of tyrosyl and tryptophyl residues in proteins. I. Solvent perturbation data of model compounds.
Topics: Deuterium; Erythritol; Glucose; Glycerol; Glycols; Indicators and Reagents; Methanol; Muramidase; Protein Denaturation; Proteins; Ribonucleases; Spectrophotometry; Sucrose; Sulfoxides; Tryptophan; Tyrosine; Urea | 1968 |
High-resolution nuclear magnetic resonance spectra of selectively deuterated staphylococcal nuclease.
Topics: Amino Acids; Asparagine; Aspartic Acid; Calcium; Deoxyribonucleases; Deuterium; Glutamates; Glutamine; Histidine; Magnetic Resonance Spectroscopy; Methionine; Nucleotides; Ribonucleases; Staphylococcus; Tryptophan; Tyrosine | 1968 |
Kinetic properties of the alpha-lytic protease of Sorangium sp., a bacterial homologue of the pancreatopeptidases.
Topics: Acetates; Amino Acid Sequence; Arginine; Bacteria; Catalysis; Chymotrypsin; Deuterium; Electrophoresis; Esters; Histidine; Hydrogen-Ion Concentration; Kinetics; Nitrophenols; Pancreatic Elastase; Peptide Hydrolases; Protease Inhibitors; Protein Binding; Serine; Spectrophotometry; Trypsin; Tryptophan; Tyrosine | 1969 |
Solvent perturbation studies of heme proteins and other colored proteins.
Topics: Animals; Catalase; Cattle; Cetacea; Cytochromes; Deuterium; Glycerol; Glycols; Heme; Hemoglobins; Horses; Hydrogen-Ion Concentration; Liver; Myoglobin; Optical Rotatory Dispersion; Solvents; Spectrum Analysis; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays; Urea; Water | 1969 |
Location of hydrogen transfer steps in the mechanism of reduction of L-amino acid oxidase.
Topics: Amino Acid Oxidoreductases; Chemical Phenomena; Chemistry; Deuterium; Flavin-Adenine Dinucleotide; Glycine; Hydrogen; Kinetics; Phenylalanine; Spectrophotometry; Tritium; Tyrosine | 1969 |
Role of bivalent cations in the phosphoglucomutase system. II. Metal ion binding and the structure of binary enzyme-metal complexes.
Topics: Animals; Cadmium; Cobalt; Deuterium; Dimethyl Sulfoxide; Glycols; Guanidines; Magnesium; Manganese; Nickel; Phosphoglucomutase; Propylene Glycols; Protein Binding; Rabbits; Solvents; Spectrophotometry; Spectrum Analysis; Tryptophan; Tyrosine; Ultraviolet Rays; Zinc | 1969 |
Exchange of carbon-bound hydrogen atoms ortho to the hydroxyl group in tyrosine.
Topics: Catalysis; Chemical Phenomena; Chemistry; Deuterium; Protons; Tritium; Tyrosine | 1965 |
The spatial location of chromophoric residues in L-glutamate dehydrogenase.
Topics: Chemical Phenomena; Chemistry, Physical; Deuterium; Glucose; Glutamate Dehydrogenase; Glycerol; Glycols; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 1966 |
Chymotrypsin-catalyzed hydrolysis of m-, p-, and o-nitroanilides of N-benzoyl-L-tyrosine.
Topics: Anilides; Chemical Phenomena; Chemistry; Chymotrypsin; Deuterium; Kinetics; Spectrophotometry; Tyrosine | 1966 |
Rate-determining step in the action of L-amino-acid oxidase.
Topics: Amino Acid Oxidoreductases; Deuterium; Glycine; Kinetics; Tyrosine | 1966 |
Retention of deuterium in p-tyrosine formed enzymatically from p-deuterophenylalanine.
Topics: Benzoates; Deuterium; Magnetic Resonance Spectroscopy; Mixed Function Oxygenases; Phenylalanine; Pseudomonas; Spectrum Analysis; Tyrosine | 1966 |
Hydrogen-deuterium exchange studies on guanidinated pig heart lactate dehydrogenase.
Topics: Animals; Arginine; Deuterium; Drug Stability; Homoarginine; Hot Temperature; Kinetics; L-Lactate Dehydrogenase; Lysine; Myocardium; Protein Conformation; Swine; Tryptophan; Tyrosine | 1983 |
The combined use of selective deuteration and double resonance experiments in assigning the 1H resonances of valine and tyrosine residues of dihydrofolate reductase.
Topics: Deuterium; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Protein Binding; Protein Conformation; Tetrahydrofolate Dehydrogenase; Tyrosine; Valine | 1984 |
The effect of nitration and D2O on the kinetics of beef heart mitochondrial adenosine triphosphatase.
Topics: Adenosine Triphosphatases; Animals; Cattle; Deuterium; Kinetics; Methane; Mitochondria, Heart; Oxidation-Reduction; Oxidative Phosphorylation Coupling Factors; Proton-Translocating ATPases; Tetranitromethane; Tyrosine | 1981 |
Detection of heterozygous carriers for phenylketonuria by a L-[2H5]phenylalanine stable isotope loading test.
Topics: Deuterium; Female; Genetic Carrier Screening; Humans; Kinetics; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1984 |
The use of deuterated phenylalanine for the in vivo assay of phenylalanine hydroxylase activity in children.
Topics: Child; Child, Preschool; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Infant; Phenylalanine; Phenylalanine Hydroxylase; Time Factors; Tyrosine | 1982 |
Stereospecificity of phenylalanine plasma kinetics and hydroxylation in man following oral application of a stable isotope-labelled pseudo-racemic mixture of L- and D-phenylalanine.
Topics: Adult; Chromatography, High Pressure Liquid; Deuterium; Humans; Hydroxylation; Kinetics; Mass Spectrometry; Nitrogen Isotopes; Phenylalanine; Stereoisomerism; Tyrosine | 1983 |
Urinary excretion of deuterated metabolites in patients with tyrosinemia type I after oral loading with deuterated L-tyrosine.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Acetoacetates; Amino Acid Metabolism, Inborn Errors; Deuterium; Female; Heptanoates; Heptanoic Acids; Humans; Hydrolases; Infant; Liver; Male; Tyrosine | 1983 |
State of Tyr49 in a mutant tryptophan synthase alpha-subunit substituted at position 49.
Topics: Chemical Phenomena; Chemistry; Circular Dichroism; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Mutation; Protein Conformation; Spectrophotometry, Ultraviolet; Tryptophan Synthase; Tyrosine | 1980 |
The conversion of phenylalanine to tyrosine in man. Direct measurement by continuous intravenous tracer infusions of L-[ring-2H5]phenylalanine and L-[1-13C] tyrosine in the postabsorptive state.
Topics: Absorption; Adult; Carbon Isotopes; Deuterium; Humans; Infusions, Parenteral; Isotope Labeling; Male; Phenylalanine; Tyrosine | 1982 |
Dynamics of amino acid side chains in membrane proteins by high field solid state deuterium nuclear magnetic resonance spectroscopy. Phenylalanine, tyrosine, and tryptophan.
Topics: Bacteriorhodopsins; Carotenoids; Deuterium; Halobacterium; Magnetic Resonance Spectroscopy; Membrane Proteins; Phenylalanine; Protein Conformation; Tryptophan; Tyrosine | 1981 |
Electronic spectroscopy and deuteration kinetics of tyrosine and tryptophan residues: an application to the study of erabutoxin b.
Topics: Deuterium; Elapid Venoms; Erabutoxins; Kinetics; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1980 |
A new rearrangement reaction in tyrosine metabolism.
Topics: Chemical Phenomena; Chemistry; Chromatography, Gas; Deuterium; Feces; Humans; Mass Spectrometry; Phenylketonurias; Phenylpropionates; Tyrosine | 1980 |
Site-specific deuteration of tyrosine and their assay by selective ion monitoring method.
Topics: Chromatography, Gas; Deuterium; Isotope Labeling; Protein Binding; Tyrosine | 1980 |
Site-directed isotope labelling and FTIR spectroscopy of bacteriorhodopsin.
Topics: Bacteriorhodopsins; Cell-Free System; Codon; Deuterium; Halobacterium salinarum; Isotope Labeling; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Folding; RNA, Transfer, Tyr; Spectroscopy, Fourier Transform Infrared; Sulfur Radioisotopes; Suppression, Genetic; Tritium; Tyrosine | 1994 |
Riboflavin sensitized photooxidation of tyrosine.
Topics: Azides; Catalase; Chromatography, Gel; Deuterium; Hydrogen Peroxide; Hydroxyl Radical; Light; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Photochemistry; Riboflavin; Spectrometry, Fluorescence; Superoxide Dismutase; Superoxides; Tyrosine | 1994 |
Point-mutations affecting the properties of tyrosineD in photosystem II. Characterization by isotopic labeling and spectral simulation.
Topics: Cyanobacteria; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Isotope Labeling; Light; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Photosynthesis; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Tyrosine | 1994 |
The dark stable tyrosine radical of photosystem 2 studied in three species using ENDOR and EPR spectroscopies.
Topics: Animals; Chlamydomonas reinhardtii; Cyanobacteria; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Photosynthetic Reaction Center Complex Proteins; Plants; Protons; Tyrosine | 1994 |
Determination of the isotope enrichment of one or a mixture of two stable labelled tracers of the same compound using the complete isotopomer distribution of an ion fragment; theory and application to in vivo human tracer studies.
Topics: Carbon Dioxide; Carbon Isotopes; Deuterium; Gas Chromatography-Mass Spectrometry; Glucose; Humans; Indicators and Reagents; Isotope Labeling; Isotopes; Leucine; Models, Biological; Oxidation-Reduction; Radioisotopes; Tyrosine | 1993 |
Alternative model for mechanism-based inhibition of Escherichia coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine 5'-diphosphate.
Topics: Azides; Cysteine; Deoxyuracil Nucleotides; Deuterium; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Models, Chemical; Mutation; Nitrogen; Ribonucleotide Reductases; Spin Labels; Tyrosine | 1993 |
Spectroscopic evidence from site-directed mutants of Synechocystis PCC6803 in favor of a close interaction between histidine 189 and redox-active tyrosine 160, both of polypeptide D2 of the photosystem II reaction center.
Topics: Cyanobacteria; Deuterium; Electron Spin Resonance Spectroscopy; Histidine; Hydrogen Bonding; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Plasmids; Restriction Mapping; Transformation, Bacterial; Tyrosine | 1993 |
Role of tyrosine 143 in lactate dehydrogenation by flavocytochrome b2. Primary kinetic isotope effect studies with a phenylalanine mutant.
Topics: Catalysis; Cytochrome c Group; Deuterium; Flavins; Flow Injection Analysis; Isotope Labeling; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Lactates; Models, Chemical; Mutation; Oxidation-Reduction; Tritium; Tyrosine | 1994 |
Tyrosyl radicals in photosystem II.
Topics: Carbon Isotopes; Chromatography, Ion Exchange; Cyanobacteria; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Indicators and Reagents; Isotope Labeling; Organelles; Oxidation-Reduction; Oxygen; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Spectroscopy, Fourier Transform Infrared; Tyrosine | 1995 |
Twenty-four-hour intravenous and oral tracer studies with L-[1-13C]phenylalanine and L-[3,3-2H2]tyrosine at a tyrosine-free, generous phenylalanine intake in adults.
Topics: Administration, Oral; Adult; Carbon Dioxide; Carbon Isotopes; Circadian Rhythm; Deuterium; Humans; Hydroxylation; Injections, Intravenous; Leucine; Male; Oxidation-Reduction; Phenylalanine; Tyrosine | 1996 |
High field EPR studies of mouse ribonucleotide reductase indicate hydrogen bonding of the tyrosyl radical.
Topics: Animals; Deuterium; Electron Spin Resonance Spectroscopy; Hydrogen Bonding; Mice; Recombinant Proteins; Ribonucleotide Reductases; Tyrosine | 1996 |
In situ analysis of peptidyl DOPA in mussel byssus using rotational-echo double-resonance NMR.
Topics: Animals; Bivalvia; Carbon Isotopes; Cross-Linking Reagents; Deuterium; Dihydroxyphenylalanine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Peptides; Tyrosine | 1996 |
New conformational properties induced by the replacement of Tyr-64 in Desulfovibrio vulgaris Hildenborough ferricytochrome c553 using isotopic exchanges monitored by mass spectrometry.
Topics: Cytochrome c Group; Desulfovibrio vulgaris; Deuterium; Electrons; Hydrogen Bonding; Molecular Weight; Mutation; Oxidation-Reduction; Peptide Fragments; Protein Conformation; Solvents; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 1996 |
Whole body protein metabolism in children with cancer.
Topics: Adolescent; Amino Acids; Carbon Isotopes; Child; Child, Preschool; Deuterium; Female; Humans; Kinetics; Leucine; Male; Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins; Tyrosine | 1996 |
Determination of p-hydroxyphenylpyruvate, p-hydroxyphenyllactate and tyrosine in normal human plasma by gas chromatography-mass spectrometry isotope-dilution assay.
Topics: Carbon Isotopes; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Indicator Dilution Techniques; Phenylpropionates; Phenylpyruvic Acids; Tyrosine | 1997 |
Proximity of acetate, manganese, and exchangeable deuterons to tyrosine YZ. in acetate-inhibited photosystem II membranes: implications for the direct involvement of YZ. in water-splitting.
Topics: Acetates; Cell Membrane; Cyanobacteria; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Manganese; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Tyrosine; Water | 1997 |
Fourier transform infrared difference spectroscopy of photosystem II tyrosine D using site-directed mutagenesis and specific isotope labeling.
Topics: Bacterial Proteins; Carbon Isotopes; Cyanobacteria; Deuterium; Histidine; Infrared Rays; Light; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Spectroscopy, Fourier Transform Infrared; Tyrosine | 1997 |
Tyrosine and tryptophan structure markers in hemoglobin ultraviolet resonance Raman spectra: mode assignments via subunit-specific isotope labeling of recombinant protein.
Topics: Crystallography, X-Ray; Deuterium; Deuterium Oxide; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hemoglobins; Humans; Hydrogen Bonding; Mass Spectrometry; Models, Molecular; Protein Conformation; Recombinant Proteins; Spectrum Analysis, Raman; Tryptophan; Tyrosine | 1997 |
Effects of cachexia due to cancer on whole body and skeletal muscle protein turnover.
Topics: Adult; Aged; Blood Proteins; Cachexia; Carbon Isotopes; Carcinoma; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Muscle, Skeletal; Nutrition Disorders; Phenylalanine; Protein Biosynthesis; Proteins; Radiopharmaceuticals; Stomach Neoplasms; Tyrosine | 1998 |
Characterization of a buried neutral histidine in Bacillus circulans xylanase: internal dynamics and interaction with a bound water molecule.
Topics: Bacillus; Deuterium; Histidine; Hydrogen; Hydrogen-Ion Concentration; Hydroxides; Kinetics; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Protein Binding; Serine; Tyrosine; Water; Xylan Endo-1,3-beta-Xylosidase; Xylosidases | 1998 |
Local control of peptide conformation: stabilization of cis proline peptide bonds by aromatic proline interactions.
Topics: Deuterium; Kinetics; Molecular Conformation; Peptides; Phenylalanine; Proline; Protein Folding; Stereoisomerism; Thermodynamics; Tyrosine | 1998 |
Twenty-four-hour L-[1-(13)C]tyrosine and L-[3,3-(2)H2]phenylalanine oral tracer studies at generous, intermediate, and low phenylalanine intakes to estimate aromatic amino acid requirements in adults.
Topics: Adolescent; Adult; Amino Acids; Carbon Isotopes; Circadian Rhythm; Deuterium; Diet; Female; Humans; Hydroxylation; Kinetics; Male; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Tyrosine | 1998 |
Tyrosine structural changes detected during the photoactivation of rhodopsin.
Topics: Amino Acid Sequence; Animals; Cell Line; Deuterium; Protein Conformation; Recombinant Proteins; Rhodopsin; Spectroscopy, Fourier Transform Infrared; Spodoptera; Transfection; Tyrosine | 1998 |
Stabilization of radical intermediates by an active-site tyrosine residue in methylmalonyl-CoA mutase.
Topics: Amino Acid Substitution; Binding Sites; Cobamides; Crystallization; Crystallography, X-Ray; Deuterium; Enzyme Stability; Free Radicals; Kinetics; Methylmalonyl-CoA Mutase; Mutagenesis, Site-Directed; Phenylalanine; Propionibacterium; Tritium; Tyrosine | 1998 |
Hydrogen bonding, solvent exchange, and coupled proton and electron transfer in the oxidation and reduction of redox-active tyrosine Y(Z) in Mn-depleted core complexes of photosystem II.
Topics: Chlorophyll; Cyanobacteria; Deuterium; Electron Spin Resonance Spectroscopy; Electron Transport; Free Radicals; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Manganese; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Protons; Solvents; Tyrosine; Water | 1998 |
Vascular sources of phenylalanine, tyrosine, lysine, and methionine for casein synthesis in lactating goats.
Topics: Animals; Carbon Isotopes; Caseins; Deuterium; Female; Goats; Hydroxylation; Kinetics; Lactation; Lysine; Mammary Glands, Animal; Methionine; Phenylalanine; Tyrosine | 1999 |
Demonstration by ultraviolet resonance Raman spectroscopy of differences in DNA organization and interactions in filamentous viruses Pf1 and fd.
Topics: Capsid; Deoxyguanosine; Deuterium; DNA, Viral; Genome, Viral; Hydrogen Bonding; Inovirus; Nucleic Acid Conformation; Pyrimidines; Scattering, Radiation; Spectrum Analysis, Raman; Tyrosine; Ultraviolet Rays; Virion; Virus Assembly | 1999 |
Protein metabolism in glucagonoma.
Topics: Adult; Amino Acids; Blood Glucose; C-Peptide; Deuterium; Female; Glucagon; Glucagonoma; Humans; Infusions, Intravenous; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins; Reference Values; Tyrosine | 1999 |
Direct evidence for a tyrosine radical in the reaction of cytochrome c oxidase with hydrogen peroxide.
Topics: Copper; Deuterium; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Free Radicals; Hydrogen Peroxide; Manganese; Paracoccus denitrificans; Protons; Tyrosine | 1999 |
Functional conformation changes in the TF(1)-ATPase beta subunit probed by 12 tyrosine residues.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Amino Acid Substitution; Bacillus; Conserved Sequence; Deuterium; Hydrogen-Ion Concentration; Ligands; Models, Molecular; Mutation; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proton-Translocating ATPases; Protons; Temperature; Titrimetry; Tyrosine | 1999 |
Roles of tyrosine 158 and lysine 165 in the catalytic mechanism of InhA, the enoyl-ACP reductase from Mycobacterium tuberculosis.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Catalysis; Circular Dichroism; Deuterium; Histidine; Kinetics; Lysine; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; NAD; Oxidoreductases; Peptide Fragments; Recombinant Proteins; Solvents; Tyrosine | 1999 |
Phenylalanine hydroxylation across the kidney in humans rapid communication.
Topics: Adult; Deuterium; Female; Hepatic Artery; Hepatic Veins; Humans; Hydroxylation; Kidney; Kinetics; Male; Phenylalanine; Phenylalanine Hydroxylase; Splanchnic Circulation; Tyrosine; Uremia | 1999 |
Gas chromatographic-tandem mass spectrometric quantification of free 3-nitrotyrosine in human plasma at the basal state.
Topics: Adult; Carbon Radioisotopes; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Nitric Oxide; Oxidative Stress; Reference Standards; Reference Values; Reproducibility of Results; Tyrosine | 1999 |
Identification of the sites of hydroxyl radical reaction with peptides by hydrogen/deuterium exchange: prevalence of reactions with the side chains.
Topics: Deuterium; Dithiothreitol; DNA Footprinting; Enkephalin, Leucine-2-Alanine; Hydrogen; Hydrogen Peroxide; Hydroxyl Radical; Iron; Leucine; Oligopeptides; Oxidation-Reduction; Peptide Fragments; Phenylalanine; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Tyrosine | 2000 |
Kinetic analysis of oxygen utilization during cofactor biogenesis in a copper-containing amine oxidase from yeast.
Topics: Amine Oxidase (Copper-Containing); Binding Sites; Coenzymes; Copper; Deuterium; Dihydroxyphenylalanine; Enzyme Precursors; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Oxygen; Oxygen Consumption; Pichia; Solvents; Temperature; Tyrosine; Viscosity | 2000 |
Tyr115, gln165 and trp209 contribute to the 1, 2-epoxy-3-(p-nitrophenoxy)propane-conjugating activity of glutathione S-transferase cGSTM1-1.
Topics: Amino Acid Substitution; Animals; Binding Sites; Chickens; Crystallography, X-Ray; Deuterium; Epoxy Compounds; Glutamine; Glutathione; Glutathione Transferase; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Nitrophenols; Oxidoreductases; Protein Conformation; Protons; Recombinant Proteins; Structure-Activity Relationship; Temperature; Tryptophan; Tyrosine | 2000 |
Orientations of Tyr 21 and Tyr 24 in the capsid of filamentous virus Ff determined by polarized Raman spectroscopy.
Topics: Amino Acid Sequence; Anisotropy; Bacteriophage M13; Capsid; Crystallography, X-Ray; Deuterium; DNA, Viral; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Spectrum Analysis, Raman; Tyrosine; Virion | 2001 |
Deuterium isotope effects during carbon-hydrogen bond cleavage by trimethylamine dehydrogenase. Implications for mechanism and vibrationally assisted hydrogen tunneling in wild-type and mutant enzymes.
Topics: Aspartic Acid; Carbon; Deuterium; Flavins; Histidine; Hot Temperature; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Methylamines; Models, Chemical; Oxidoreductases, N-Demethylating; Tyrosine | 2001 |
Inter- and intra-molecular migration of peptide amide hydrogens during electrospray ionization.
Topics: Algorithms; Amides; Aspartic Acid; Deuterium; Fourier Analysis; Hydrogen; Oligopeptides; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2001 |
Acid-base catalysis by UDP-galactose 4-epimerase: correlations of kinetically measured acid dissociation constants with thermodynamic values for tyrosine 149.
Topics: Alanine; Catalysis; Deuterium; Electron Transport; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protons; Serine; Spectrometry, Fluorescence; Temperature; Thermodynamics; Tyrosine; UDPglucose 4-Epimerase | 2001 |
High-frequency (140-GHz) time domain EPR and ENDOR spectroscopy: the tyrosyl radical-diiron cofactor in ribonucleotide reductase from yeast.
Topics: Deuterium; Electron Spin Resonance Spectroscopy; Iron Compounds; Protons; Recombinant Proteins; Ribonucleotide Reductases; Saccharomyces cerevisiae; Time Factors; Tyrosine | 2001 |
Measuring whole-body actin/myosin protein breakdown in mice using a primed constant stable isotope-infusion protocol.
Topics: Actins; Animals; Body Weight; Chromatography, Liquid; Deuterium; Infusions, Intravenous; Lipopolysaccharides; Male; Mass Spectrometry; Methylhistidines; Mice; Mice, Inbred Strains; Models, Animal; Muscles; Myosins; Phenylalanine; Radioactive Tracers; Starvation; Tyrosine | 2003 |
Oxygen and hydrogen isotope effects in an active site tyrosine to phenylalanine mutant of peptidylglycine alpha-hydroxylating monooxygenase: mechanistic implications.
Topics: Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Catalysis; Cell Line; Deuterium; Dopamine beta-Hydroxylase; Hippurates; Humans; Hydroxylation; Kinetics; Mixed Function Oxygenases; Multienzyme Complexes; Oxygen Isotopes; Phenylalanine; Tyrosine | 2003 |
Biosynthesis of structurally unique fungal metabolite GKK1032A(2): indication of novel carbocyclic formation mechanism in polyketide biosynthesis.
Topics: Antibiotics, Antineoplastic; Carbon Isotopes; Cyclization; Deuterium; Heterocyclic Compounds, 4 or More Rings; Molecular Structure; Multienzyme Complexes; Oxidation-Reduction; Penicillium; Peptide Synthases; Tyrosine | 2003 |
Role of radical formation at tyrosine 193 in the allene oxide synthase domain of a lipoxygenase-AOS fusion protein from coral.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Catalase; Cnidaria; Deuterium; Electron Spin Resonance Spectroscopy; Fatty Acids, Unsaturated; Free Radicals; Hydrogen Peroxide; Intramolecular Oxidoreductases; Leukotrienes; Lipoxygenase; Oxidation-Reduction; Peracetic Acid; Protein Structure, Tertiary; Recombinant Fusion Proteins; Reference Values; Substrate Specificity; Tyrosine | 2003 |
Nitration of endogenous para-hydroxyphenylacetic acid and the metabolism of nitrotyrosine.
Topics: Animals; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Injections, Intravenous; Lipopolysaccharides; Male; Models, Chemical; Nitrates; Nitrophenols; Nitrosation; Phenylacetates; Rats; Rats, Sprague-Dawley; Reference Standards; Tyrosine | 2003 |
A novel method for the biosynthesis of deuterated proteins with selective protonation at the aromatic rings of Phe, Tyr and Trp.
Topics: Bacterial Proteins; Deuterium; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Proteins; Protons; Shikimic Acid; Tryptophan; Tyrosine | 2003 |
Differentiation of natural and synthetic phenylalanine and tyrosine through natural abundance 2H nuclear magnetic resonance.
Topics: Animals; Animals, Genetically Modified; Benzoates; Deuterium; Magnetic Resonance Spectroscopy; Phenylalanine; Phenylethyl Alcohol; Tyrosine | 2003 |
[COMPARATIVE SPECTROSCOPIC EXAMINATION OF SOME PSEUDOMELANINS FROM N-FREE SUBSTANCES. II].
Topics: Biological Products; Chemical Phenomena; Chemistry; Deuterium; Phenols; Pigments, Biological; Potassium; Pyrogallol; Quinones; Research; Spectrum Analysis; Sulfates; Tryptophan; Tyrosine | 1964 |
Kinetics of gas-phase hydrogen/deuterium exchange and gas-phase structure of protonated phenylalanine, proline, tyrosine and tryptophan.
Topics: Amino Acids; Computer Simulation; Cyclotrons; Deuterium; Deuterium Exchange Measurement; Gases; Hydrogen; Hydrogen Bonding; Kinetics; Models, Molecular; Phase Transition; Phenylalanine; Proline; Protein Conformation; Protons; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Tryptophan; Tyrosine | 2003 |
Solvent and primary deuterium isotope effects show that lactate CH and OH bond cleavages are concerted in Y254F flavocytochrome b2, consistent with a hydride transfer mechanism.
Topics: Catalysis; Deuterium; Deuterium Exchange Measurement; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolysis; Hydroxy Acids; Kinetics; L-Lactate Dehydrogenase (Cytochrome); Lactic Acid; Mutagenesis, Site-Directed; Phenylalanine; Saccharomyces cerevisiae Proteins; Solvents; Tyrosine | 2003 |
Quantitative analysis with desorption/ionization on silicon mass spectrometry using electrospray deposition.
Topics: Amino Acid Sequence; Deuterium; Linear Models; Mass Spectrometry; Peptides; Phenylalanine; Reproducibility of Results; Silicon; Thymopentin; Tyrosine | 2003 |
Supplementation with aromatic amino acids improves leucine kinetics but not aromatic amino acid kinetics in infants with infection, severe malnutrition, and edema.
Topics: Alanine; Amino Acids, Aromatic; Anthropometry; Body Water; Deuterium; Edema; Enteral Nutrition; Humans; Infant; Infections; Intubation, Gastrointestinal; Kinetics; Leucine; Phenylalanine; Protein-Energy Malnutrition; Proteins; Tryptophan; Tyrosine | 2004 |
Role for bound water and CH-pi aromatic interactions in photosynthetic electron transfer.
Topics: Chlorophyll; Chlorophyll A; Deuterium; Electron Spin Resonance Spectroscopy; Kinetics; Models, Molecular; Oxidation-Reduction; Photosystem I Protein Complex; Spectroscopy, Fourier Transform Infrared; Synechocystis; Tyrosine; Viscosity; Water | 2005 |
Determinants of substrate specificity in omega-aminotransferases.
Topics: Amino Acids; Aminobutyrates; Binding Sites; Biochemistry; Crystallography, X-Ray; Deuterium; DNA; Glutamic Acid; Humans; Isoleucine; Ketoglutaric Acids; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Protein Binding; Pyridoxal Phosphate; Recombinant Fusion Proteins; Spectrophotometry; Substrate Specificity; Time Factors; Transaminases; Tyrosine | 2005 |
Detection of 28 neurotransmitters and related compounds in biological fluids by liquid chromatography/tandem mass spectrometry.
Topics: Amniotic Fluid; Catecholamines; Chromatography, High Pressure Liquid; Deuterium; gamma-Aminobutyric Acid; Humans; Indoles; Neurotransmitter Agents; Pterins; Reference Standards; Tandem Mass Spectrometry; Tyrosine | 2006 |
Phenylalanine and tyrosine kinetics in compensated liver cirrhosis: effects of meal ingestion.
Topics: Adult; Case-Control Studies; Deuterium; Eating; Fasting; Humans; Hydroxylation; Infusions, Intravenous; Kinetics; Liver Cirrhosis; Male; Middle Aged; Phenylalanine; Protein Biosynthesis; Severity of Illness Index; Tyrosine; Up-Regulation | 2008 |
Evidence for protein radical-mediated nuclear tunneling in fatty acid alpha-oxygenase.
Topics: Carbon; Catalysis; Deuterium; Fatty Acids; Free Radicals; Hydrogen; Kinetics; Oryza; Oxidation-Reduction; Oxygen; Oxygenases; Phenylalanine; Proteins; Spectrum Analysis; Thermodynamics; Tyrosine | 2008 |
Structural changes due to the deprotonation of the proton release group in the M-photointermediate of bacteriorhodopsin as revealed by time-resolved FTIR spectroscopy.
Topics: Aspartic Acid; Bacteriorhodopsins; Carbon Radioisotopes; Deuterium; Halobacterium salinarum; Hydrogen-Ion Concentration; Models, Molecular; Photochemistry; Protein Structure, Secondary; Protons; Schiff Bases; Spectroscopy, Fourier Transform Infrared; Tyrosine | 2008 |
Noninvasive imaging of protein metabolic labeling in single human cells using stable isotopes and Raman microscopy.
Topics: Deuterium; HeLa Cells; Humans; Methionine; Phenylalanine; Proteins; Spectrum Analysis, Raman; Tyrosine | 2008 |
Tracking radical migration in large hydrogen deficient peptides with covalent labels: facile movement does not equal indiscriminate fragmentation.
Topics: Bradykinin; Deuterium; Glycine; Kinetics; Mass Spectrometry; Models, Chemical; Peptides; Photochemistry; Thermodynamics; Tyrosine | 2009 |
Site-directed mutagenesis as a probe of the acid-base catalytic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
Topics: Alcohol Oxidoreductases; Catalysis; Deuterium; Hydrogen-Ion Concentration; Lysine; Molecular Structure; Mutagenesis, Site-Directed; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Solvents; Tyrosine; Viscosity | 2009 |
The production of intrinsically labeled milk protein provides a functional tool for human nutrition research.
Topics: Absorption; Animals; Carbon Isotopes; Cattle; Deuterium; Dietary Proteins; Digestion; Female; Humans; Isotope Labeling; Leucine; Male; Middle Aged; Milk; Milk Proteins; Muscle Proteins; Nutritional Physiological Phenomena; Phenylalanine; Research; Tyrosine | 2009 |
Glucosylthioureidocalix[4]arenes: Synthesis, conformations and gas phase recognition of amino acids.
Topics: Amino Acids; Deuterium; Gases; Hydrogen; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Molecular Conformation; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Tryptophan; Tyrosine | 2010 |
High-field 2H-Mims-ENDOR spectroscopy on PSII single crystals: hydrogen bonding of YD*.
Topics: Catalytic Domain; Deuterium; Deuterium Exchange Measurement; Electron Spin Resonance Spectroscopy; Hydrogen Bonding; Photosystem II Protein Complex; Tyrosine | 2010 |
Cyclooxygenase reaction mechanism of prostaglandin H synthase from deuterium kinetic isotope effects.
Topics: Arachidonic Acid; Biocatalysis; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Isotope Labeling; Kinetics; Oxygen; Prostaglandin-Endoperoxide Synthases; Substrate Specificity; Tyrosine | 2011 |
Determination of orientations of aromatic groups in self-assembled peptide fibrils by polarised Raman spectroscopy.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Deuterium; Magnetic Resonance Spectroscopy; Models, Theoretical; Protein Structure, Secondary; Spectrum Analysis, Raman; Tyrosine | 2013 |
Pulsed EPR study of amino acid and tetrahydropterin binding in a tyrosine hydroxylase nitric oxide complex: evidence for substrate rearrangements in the formation of the oxygen-reactive complex.
Topics: Amino Acid Substitution; Apoenzymes; Biocatalysis; Catalytic Domain; Deuterium; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Humans; Hydroxylation; Iron; Molecular Conformation; Mutant Proteins; Nerve Tissue Proteins; Nitric Oxide; Oxidation-Reduction; Protein Binding; Pterins; Quaternary Ammonium Compounds; Recombinant Proteins; Tyrosine; Tyrosine 3-Monooxygenase | 2013 |
Chirally deuterated benzyl chlorides from benzyl alcohols via hexachloroacetone/polymer-supported triphenylphosphine: synthesis of protected (2S, 3S)-[3-(2)H, (15)N]-tyrosine.
Topics: Acetone; Benzyl Alcohols; Benzyl Compounds; Deuterium; Nitrogen Isotopes; Organophosphorus Compounds; Polymers; Tyrosine | 2013 |
Isotope effects for deuterium transfer and mutagenesis of Tyr187 provide insight into controlled radical chemistry in adenosylcobalamin-dependent ornithine 4,5-aminomutase.
Topics: Catalytic Domain; Clostridium sticklandii; Deuterium; Electron Spin Resonance Spectroscopy; Intramolecular Transferases; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Tyrosine | 2014 |
The metabolism and de-bromination of bromotyrosine in vivo.
Topics: Animals; Bromine; Deuterium; Gas Chromatography-Mass Spectrometry; Male; Phenylacetates; Rats; Rats, Sprague-Dawley; Tyrosine | 2016 |
Role of a Conserved Tyrosine Residue in the FMN-Heme Interdomain Electron Transfer in Inducible Nitric Oxide Synthase.
Topics: Deuterium; Electron Transport; Heme; Hydrogen-Ion Concentration; Kinetics; Lasers; Nitric Oxide Synthase Type II; Protein Domains; Solvents; Tyrosine | 2016 |
Detection of intermolecular transferred NOEs in large protein complexes using asymmetric deuteration: HIV-1 gp120 in complex with a CCR5 peptide.
Topics: Binding Sites; Crystallography, X-Ray; Deuterium; HIV Envelope Protein gp120; Humans; Isoleucine; Leucine; Multiprotein Complexes; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Binding; Protons; Receptors, CCR5; Tyrosine; Valine | 2016 |
Hydrogen-Deuterium Exchange Mass Spectrometry Identifies Activated Factor IX-Induced molecular Changes in Activated Factor VIII.
Topics: Blood Coagulation; Deuterium; Deuterium Exchange Measurement; Factor IXa; Factor VIIIa; Hemophilia A; Humans; Leucine; Mass Spectrometry; Molecular Conformation; Mutagenesis, Site-Directed; Protein Binding; Surface Plasmon Resonance; Tyrosine | 2021 |