deuterium has been researched along with tryptophan in 153 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 84 (54.90) | 18.7374 |
1990's | 27 (17.65) | 18.2507 |
2000's | 31 (20.26) | 29.6817 |
2010's | 8 (5.23) | 24.3611 |
2020's | 3 (1.96) | 2.80 |
Authors | Studies |
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Nakanishi, M; Tsuboi, M | 1 |
Curtius, HC; Gitzelmann, R; Otten, A; Wegmann, H | 1 |
Beck, O; Sedvall, G; Wiesel, FA | 1 |
Moore, GR; Williams, RJ | 1 |
Grinvald, A; Pecht, I; Schlessinger, J; Steinberg, IZ | 1 |
Campbell, ID; Dobson, CM; Williams, JP | 1 |
Matthews, HR; Matthews, KS; Opella, SJ | 1 |
Nakanishi, M | 1 |
Dobson, CM; Woodworth, RC | 1 |
Curtius, HC; Redweik, U; Wegmann, H | 1 |
Bradbury, JH; Norton, RS | 3 |
Hirakwa, AY; Nakanishi, M; Takesada, H; Tsuboi, M | 1 |
Burgen, AS; Feeney, J; Griffiths, DV; Roberts, GC | 1 |
Punyiczki, M; Rosenberg, A | 1 |
Harada, I; Miura, T; Takeuchi, H | 2 |
Aubrey, KL; Thomas, GJ | 1 |
Abramson, FP; Bacher, JD; Boni, RL; Heyes, MP; Ji, XD; Markey, SP; Yergey, JA | 1 |
Backes, G; Davidson, VL; Duine, JA; Huitema, F; Sanders-Loehr, J | 1 |
Brown, KA; Farnum, MF; Howell, EE; Kraut, J; Warren, MS | 1 |
Aiba, H; Hayashi, F; Kyogoku, Y; Lee, BJ; Lee, SJ | 1 |
Amonraksa, K; Da Rin-Fioretto, S; Mammi, S; Peggion, E; Simonetti, M | 1 |
Hayashi, T; Iida, Y; Todoriki, H | 1 |
Hayashi, T; Nakane, A; Naruse, H; Takesada, M; Yamazaki, K | 1 |
Karnaukhova, E; Lugtenburg, J; Niessen, WM; Raap, J; Tjaden, UR; van der Greef, J | 1 |
Goto, Y; Hamaguchi, K; Hayashi, F; Kawata, Y; Kobayashi, Y; Kyogoku, Y | 1 |
DeHaas, GH; Jain, MK; Maliwal, BP; Slotboom, AJ | 1 |
Kiick, DM; Phillips, RS | 1 |
Abe, K; Akasaka, K; Inoue, T; Kainosho, M; Tamura, A; Watari, H | 1 |
Anglister, J; Bond, MW; Frey, T; Leahy, D; Levitt, M; McConnell, HM; Rule, GS; Tomasello, J; Whittaker, M | 1 |
Endo, T; Imoto, T; Ueda, T; Yamada, H | 1 |
Morita, F; Shimizu, T; Yagi, K | 1 |
Udenfriend, S | 1 |
Ayad, SR; Barker, GR; Weigold, J | 1 |
Glickson, JD; McDonald, CC; Phillips, WD | 1 |
McConnell, HM; Morrisett, JD; Wien, RW | 1 |
Cohen, JS; Fisher, WR; Schechter, AN | 1 |
Naumann, CF; Sigel, H | 1 |
Baba, H; Song, PS | 1 |
Hunkapiller, MW; Richards, JH | 1 |
Blakley, RL; Tamao, Y | 1 |
Groudinsky, O; Keller, R; Wüthrich, K | 1 |
Christensen, HN; Quay, S | 1 |
Lindskog, S; Nilsson, A | 1 |
Coletti-Previero, MA; Previero, A; Prota, G | 1 |
Dimicoli, JL; Helene, C | 2 |
Adam, S; Arnold, W; Heinrich, CP | 1 |
Ogura, S; Sogami, M; Uyeda, M | 1 |
Arrio, B; Hill, M; Parquet, C | 1 |
Kumar, NG; Urry, DW | 1 |
Feldman, I; McGuire, R | 1 |
Roberts, GC; Rodgers, P | 1 |
Grossweiner, LI; Kepka, AG | 1 |
Jones, JB; Lewis, AJ; Sneddon, DW | 1 |
Fischer, JR; Julian, GR; Rogers, SJ | 1 |
Kukushkin, AK; Kuznetsov, AN | 1 |
Herskovits, TT; Sorensen, ME | 1 |
Glickson, JD; Mayers, DF; Settine, JM; Urry, DW | 1 |
Mori, KF | 1 |
Fuchs, HH; Herskovits, TT | 1 |
Glickson, JD; Phillips, WD; Rupley, JA | 1 |
Brewer, HB; Bronzert, TJ; Fales, HM; Milne, GW; Nagai, Y; Pisano, JJ | 1 |
Biaglow, JE; Mieyal, JJ; Sable, HZ; Suchy, J | 1 |
Aronson, JF; Morales, MF | 1 |
Bak, B; Led, JJ; Pedersen, EJ | 1 |
Steiner, RF; Weinryb, I | 1 |
Föry, W; MacKenzie, RE; McCormick, DB; Wu, FY | 1 |
Lehrer, SS | 1 |
Fujiwara, M; Kampa, L; Patel, DJ; Shulman, RG; Yamane, T | 1 |
Lord, RC; Yu, NT | 1 |
Cohen, JS | 1 |
Kayne, FJ; Suelter, CH | 1 |
Herskovits, TT; Sorensen, M | 1 |
Jardetzky, O; Markley, JL; Putter, I | 1 |
Kaplan, H; Whitaker, DR | 1 |
Herskovits, TT | 1 |
Davis, JG; Donovan, JW; Zahnley, JC | 1 |
Peck, EJ; Ray, WJ | 1 |
Cross, DG; Fisher, HF | 1 |
Williams, EJ | 1 |
Cope, BT; Crespi, HL; Katz, JJ; Smith, U | 1 |
Abe, M; Nakanishi, M; Nosoh, Y; Tsuboi, M | 1 |
Burgen, AS; Feeney, J; Griffiths, DV; King, RW; Roberts, GC; Thomson, JW | 1 |
Nakanishi, M; Shimizu, H; Tsuboi, M; Yamada, T | 1 |
Dwek, RA; Gettins, P | 1 |
Kinsey, RA; Kintanar, A; Oldfield, E | 1 |
Kobayashi, M; Nakanishi, M; Takasaki, C; Tamiya, N; Tsuboi, M | 1 |
Belikov, VM; Dementieva, IS; Faleev, NG; Gogoleva, OI; Zakomirdina, LN | 1 |
McDermott, AE; Williams, JC | 1 |
Gräslund, A; Lassmann, G; Pötsch, S; Sahlin, M; Sjöberg, BM; Slaby, A | 1 |
Cohen, JD; Fink, GR; Normanly, J | 1 |
Richards, FM; Sykes, BD; Wishart, DS | 1 |
Brooks, HB; Davidson, VL; Jones, LH | 1 |
Heelis, PF; Kim, ST; Sancar, A | 1 |
London, RE; Luck, LA; O'Connell, TM; Vance, JE | 1 |
Phillips, RS; Sloan, MJ | 1 |
Hu, X; Spiro, TG | 1 |
Maruyama, T; Takeuchi, H | 1 |
Arrowsmith, CH; Gardner, KH; Kay, LE; Muhandiram, DR; Shan, X | 1 |
Killian, JA; Lindblom, G; Persson, S | 1 |
Jonasson, P; Jonsson, BH; Kjellsson, A; Sethson, I | 1 |
Arata, Y; Ito, S; Kawaminami, S; Shimada, I; Takahashi, H | 1 |
Busath, DD; Cotten, M; Cross, TA; Shirts, RB; Tian, C | 1 |
Hoekstra, D; Martin, I; Pécheur, EI; Ruysschaert, JM | 1 |
Devasagayam, TP; Kamat, JP | 1 |
Chin, JK; Klinman, JP | 1 |
Fischer, CJ; Gafni, A; Schauerte, JA; Steel, DG; Wisser, KC | 2 |
Andersen, OS; Greathouse, DV; Hatchett, J; Jude, AR; Koeppe, RE; Providence, LL | 1 |
Chung, EW; Dobson, CM; Jamin, M; Matagne, A; Radford, SE; Robinson, CV | 1 |
Chern, MK; Chou, CC; Hsiao, CD; Hsieh, CH; Kuan, IC; Liu, LF; Tam, MF; Wu, TC; Yeh, YH | 1 |
Ferry, JG; Tripp, BC | 1 |
Babu, KR; Douglas, DJ | 1 |
Astot, C; Crozier, A; Edlund, A; Sandberg, G; Sitbon, F | 1 |
Klinman, JP; Tsai , S | 1 |
Chen, R; Raj, V; Spiro, TG; Zhao, X | 1 |
Arshava, B; Becker, JM; Ding, FX; Naider, F; Xie, H | 1 |
Betz, M; Hartleib, J; Katsemi, V; Löhr, F; Rüterjans, H | 1 |
Ito, Y; Laue, ED; Nakayama, H; Nietlispach, D; Rajesh, S; Shibata, T; Takio, K | 1 |
CHRISTOMANOS, AA; GARDIKI, V | 1 |
HENDERSON, LE; STEVENS, CO; TOLBERT, BM | 1 |
HOLMES, LG; KRONMAN, MJ | 1 |
Greathouse, DV; Koeppe, RE; Pulay, P; Scherer, EM; Sun, H; van der Wel, PC | 1 |
Bergt, C; d'Avignon, A; Fu, X; Heinecke, JW; Huq, NP; Kao, JL; Kassim, SY; Mecham, RP; Parks, WC | 1 |
Kazazić, S; Klasinc, L; Rozman, M; Srzić, D | 1 |
Dick, RA; Kensler, TW | 1 |
Russu, IM | 1 |
Aubert, C; Brettel, K; Byrdin, M; Eker, AP; Mathis, P; Sartor, V; Vos, MH | 1 |
Malthouse, JP; Níbeilliú, ME | 1 |
Badaloo, A; Forrester, T; Heird, WC; Jahoor, F; Reid, M | 1 |
van der Donk, WA; Woodyer, R; Zhao, H | 1 |
Bernhard, F; Dötsch, V; Löhr, F; Rogov, VV; Shi, M | 1 |
Borisov, YA; Dadayan, AK; Myasoedov, NF; Zolotarev, YA | 1 |
Gaede, HC; Gawrisch, K; Yau, WM | 1 |
Fitzpatrick, PF; Pavon, JA | 1 |
Daily, AE; Greathouse, DV; Koeppe, RE; van der Wel, PC | 1 |
Callow, P; Forsyth, VT; Haertlein, M; Laux, V; Svergun, DI; Timmins, PA | 1 |
Andersen, OS; Greathouse, DV; Koeppe, RE; Sun, H | 1 |
Adio, AM; Okinyo-Owiti, DP; Pedras, MSC; Thoms, K | 1 |
Baldini, L; Casnati, A; Kalenius, E; Neitola, R; Sansone, F; Torvinen, M; Ungaro, R; Vainiotalo, P | 1 |
Dabrowski, P; Kanska, M; Winek, T; Winnicka, E | 1 |
Dieng, SD; Schelvis, JP | 1 |
Bisaccia, M; Konrat, R; Lichtenecker, RJ; Sára, T; Schmid, W; Schörghuber, J | 1 |
Absillis, G; Goovaerts, V; Parac-Vogt, TN; Stroobants, K | 1 |
Kańska, M; Szymańska, J; Winnicka, E | 1 |
Das, TK; Fu, J; Hageman, T; Kuehne, P; Leone, A; Ludwig, R; Tao, L; Wei, H; Zocher, M | 1 |
Halenova, T; Maximova, T; Pleteneva, T; Syroeshkin, A; Zlatskiy, I | 1 |
Buller, AR; Cavagnero, S; McDonald, AD; Thompson, CM; Yang, H | 1 |
Elliott, MA; Nanga, RPR; Reddy, R; Soni, ND; Swago, S; Swain, A; Wilson, N; Witschey, WR | 1 |
Afsari, S; Ghirlanda, G; Halloran, N; Lindsay, S; Mukherjee, S; Ryan, E; Wang, X | 1 |
3 review(s) available for deuterium and tryptophan
Article | Year |
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[Thermal fluctuation of protein structures (author's transl)].
Topics: Animals; Cattle; Deuterium; Hot Temperature; Hydrogen; Membrane Proteins; Protein Conformation; Tryptophan | 1978 |
Arene oxide intermediates in enzymatic hydroxylation and their significance with respect to drug toxicity.
Topics: Acetanilides; Amphetamine; Bromine; Chemical Phenomena; Chemistry; Chlorine; Deuterium; Ethers, Cyclic; Fenclonine; Fluorine; Glutathione; Mixed Function Oxygenases; Naphthalenes; Phenols; Phenylalanine; Phenylpyruvic Acids; Tritium; Tryptophan | 1971 |
Intraprotein electron transfer and proton dynamics during photoactivation of DNA photolyase from E. coli: review and new insights from an "inverse" deuterium isotope effect.
Topics: Deoxyribodipyrimidine Photo-Lyase; Deuterium; Electron Transport; Energy Metabolism; Escherichia coli; Kinetics; Models, Biological; Photobiology; Proton-Motive Force; Spectrophotometry; Tryptophan | 2004 |
1 trial(s) available for deuterium and tryptophan
Article | Year |
---|---|
[Metabolic changes in aromatic amino acids and monoamines in infantile autism and development of new treatment related to the finding].
Topics: 5-Hydroxytryptophan; Amino Acids; Autistic Disorder; Biogenic Monoamines; Biopterins; Carbon Isotopes; Child; Child, Preschool; Clinical Trials as Topic; Deuterium; Double-Blind Method; Humans; Levodopa; Phenylalanine; Tryptophan | 1989 |
149 other study(ies) available for deuterium and tryptophan
Article | Year |
---|---|
Overall and localized fluctuation in the structure of a protein molecule.
Topics: Animals; Chemical Phenomena; Chemistry; Chickens; Chlorides; Deuterium; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Lithium; Muramidase; Ovalbumin; Peptides; Protein Conformation; Protein Denaturation; Proteins; Temperature; Thermodynamics; Tryptophan | 1979 |
Nutritive value of N-acetyl-L-tryptophan in man.
Topics: Blood Proteins; Deuterium; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Nutritive Value; Tryptophan | 1979 |
Mass fragmentographic determination of 5-hydroxytryptamine and 5-hydroxyindole-3-acetic acid in brain tissue using deuterated internal standards.
Topics: Animals; Brain; Brain Chemistry; Deuterium; Fenclonine; Gas Chromatography-Mass Spectrometry; Hydroxyindoleacetic Acid; Male; Microchemistry; Pargyline; Probenecid; Rats; Reserpine; Serotonin; Tryptophan | 1977 |
Assignment of aromatic amino acid PMR resonances of horse ferrocytochrome C.
Topics: Animals; Chemical Phenomena; Chemistry; Cytochrome c Group; Deuterium; Horses; Magnetic Resonance Spectroscopy; Protons; Tryptophan; Tyrosine | 1975 |
Homogeneity and variability in the structure of azurin molecules studied by fluorescence decay and circular polarization.
Topics: Amides; Apoproteins; Azurin; Bacterial Proteins; Deuterium; Hydrogen-Ion Concentration; Kinetics; Mathematics; Protein Conformation; Pseudomonas aeruginosa; Quantum Theory; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan | 1975 |
Studies of exchangeable hydrogens in lysozyme by means of Fourier transform proton magnetic resonance.
Topics: Animals; Chickens; Deuterium; Female; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Muramidase; Protein Conformation; Spectrum Analysis; Tryptophan | 1975 |
Selectively deuterated amino acid analogues. Synthesis, incorporation into proteins and NMR properties.
Topics: Amino Acids; Bacterial Proteins; Chemical Phenomena; Chemistry; Deuterium; Enzyme Repression; Escherichia coli; Histidine; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Tryptophan; Tyrosine | 1977 |
Selective substitution of 2H and 3H into aromatic amino acids catalyzed by Raney nickel.
Topics: Chemical Phenomena; Chemistry; Deuterium; Magnetic Resonance Spectroscopy; Nickel; Phenylalanine; Tritium; Tryptophan; Tyrosine | 1979 |
Selective ion monitoring of tryptophan, N-acetyltryptophan and kynurenine in human serum. Application to the in vivo measurement of tryptophan pyrrolase activity.
Topics: Acetylation; Deuterium; Humans; Kynurenine; Monitoring, Physiologic; Trimethylsilyl Compounds; Tryptophan; Tryptophan Oxygenase | 1978 |
Kinetics of hydrogen-deuterium exchange of tryptophan and tryptophan peptides in deutero-trifluoroacetic acid using proton magenetic resonance spectroscopy.
Topics: Deuterium; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Oligopeptides; Protein Conformation; Temperature; Thermodynamics; Tryptophan | 1976 |
Hydrogen-deuterium exchange of the tryptophan residues in bovine alpha-lactalbumin.
Topics: Animals; Deuterium; Hydrogen; In Vitro Techniques; Kinetics; Lactalbumin; Spectrum Analysis; Tryptophan | 1976 |
Preparation of selectively deuterated aromatic amino acids for use in 1H NMR studies of proteins.
Topics: Deuterium; Histidine; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Tryptophan; Tyrosine | 1976 |
Proton magnetic resonance spectroscopic studies of proteins containing deuterated tryptophan residues.
Topics: Deuterium; Lactalbumin; Lactoglobulins; Magnetic Resonance Spectroscopy; Muramidase; Protein Conformation; Tryptophan | 1976 |
The effect of viscosity on the accessibility of the single tryptophan in human serum albumin.
Topics: Deuterium; Ethylene Glycol; Ethylene Glycols; Fluorescence; Glycerol; Humans; Hydrogen; Hydrogen-Ion Concentration; Protein Conformation; Serum Albumin; Spectrophotometry, Ultraviolet; Tryptophan; Viscosity | 1992 |
Raman spectroscopic characterization of tryptophan side chains in lysozyme bound to inhibitors: role of the hydrophobic box in the enzymatic function.
Topics: Acetylglucosamine; Amino Acid Sequence; Animals; Chickens; Deuterium; Deuterium Oxide; Female; Hydrogen Bonding; Models, Molecular; Muramidase; Protein Binding; Protein Conformation; Spectrum Analysis, Raman; Tryptophan; Water | 1991 |
Raman spectroscopy of filamentous bacteriophage Ff (fd, M13, f1) incorporating specifically-deuterated alanine and tryptophan side chains. Assignments and structural interpretation.
Topics: Alanine; Capsid; Coliphages; Deuterium; DNA, Bacterial; DNA, Single-Stranded; DNA, Viral; Nucleic Acid Conformation; Protein Conformation; Spectrum Analysis, Raman; Tryptophan | 1991 |
Stable isotope-labeled tryptophan as a precursor for studying the disposition of quinolinic acid in rabbits.
Topics: Animals; Deuterium; Half-Life; Kynurenine; Male; Quinolinic Acid; Quinolinic Acids; Rabbits; Tissue Distribution; Tryptophan | 1991 |
Characterization of the tryptophan-derived quinone cofactor of methylamine dehydrogenase by resonance Raman spectroscopy.
Topics: Ammonia; Deuterium; Hydroxides; Methylamines; Motion; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Paracoccus denitrificans; Quinones; Spectrum Analysis; Spectrum Analysis, Raman; Thiobacillus; Tryptophan | 1991 |
Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
Topics: Coenzymes; Deuterium; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Methotrexate; Mutagenesis, Site-Directed; NADP; Protein Binding; Structure-Activity Relationship; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Tryptophan | 1991 |
A nuclear magnetic resonance study of the cyclic AMP receptor protein (CRP): assignments of the NH protons of histidine and tryptophan residues and the effect of binding of cAMP to CRP.
Topics: Carrier Proteins; Cyclic AMP; Cyclic AMP Receptor Protein; Cyclic GMP; Deuterium; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Protein Conformation; Protons; Receptors, Cyclic AMP; Spectrum Analysis; Tryptophan | 1990 |
Synthesis and 1H-NMR studies of alpha-deuterated analogues of des-Trp1, Nle12-human minigastrin.
Topics: Amino Acid Sequence; Deuterium; Gastrins; Glutamates; Humans; Molecular Sequence Data; Peptides; Temperature; Tryptophan | 1990 |
Highly sensitive method for the determination of 1-methyl-1,2,3,4-tetrahydro-beta-carboline using combined capillary gas chromatography and negative-ion chemical ionization mass spectrometry.
Topics: Adult; Carbolines; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Male; Reference Values; Tryptamines; Tryptophan | 1990 |
Determination of deuterium-labeled tryptophan in proteins by means of high-performance liquid chromatography and thermospray mass spectrometry.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Deuterium; Gas Chromatography-Mass Spectrometry; Halobacterium; Isothiocyanates; Isotope Labeling; Proteins; Thiocyanates; Tryptophan | 1989 |
Hydrogen-exchange kinetics of the indole NH proton of the buried tryptophan in the constant fragment of the immunoglobulin light chain.
Topics: Bence Jones Protein; Deuterium; Humans; Hydrogen; Hydrogen-Ion Concentration; Immunoglobulin Light Chains; Kinetics; Magnetic Resonance Spectroscopy; Papain; Protein Conformation; Protein Denaturation; Protons; Tryptophan | 1988 |
Anchoring of phospholipase A2: the effect of anions and deuterated water, and the role of N-terminus region.
Topics: Amino Acid Sequence; Anions; Catalysis; Deuterium; Deuterium Oxide; Glycerophospholipids; Hydrolysis; Kinetics; Lipid Bilayers; Peptide Fragments; Phosphatidic Acids; Phospholipases; Phospholipases A; Phospholipases A2; Protein Binding; Tryptophan; Water | 1986 |
Mechanistic deductions from multiple kinetic and solvent deuterium isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Escherichia coli tryptophan indole-lyase.
Topics: Alanine; Binding, Competitive; Catalysis; Cysteine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lyases; Oxindoles; Pyridoxal Phosphate; Solvents; Tryptophan; Tryptophanase | 1988 |
Internal motion of a tryptophan residue in Streptomyces subtilisin inhibitor: deuterium nuclear magnetic resonance in solution.
Topics: Bacterial Proteins; Deuterium; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Conformation; Subtilisins; Tryptophan | 1988 |
Contribution of tryptophan residues to the combining site of a monoclonal anti dinitrophenyl spin-label antibody.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Base Sequence; Cloning, Molecular; Deuterium; Dinitrophenols; DNA; Haptens; Immunoglobulin Fab Fragments; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Magnetic Resonance Spectroscopy; Protein Conformation; Radioisotope Dilution Technique; Tryptophan | 1987 |
Characterization of individual tryptophan side chains in proteins using Raman spectroscopy and hydrogen-deuterium exchange kinetics.
Topics: Deuterium; Hydrogen; Hydrogen Bonding; Kinetics; Muramidase; Protein Conformation; Spectrum Analysis, Raman; Tryptophan | 1988 |
pH dependence of individual tryptophan N-1 hydrogen exchange rates in lysozyme and its chemically modified derivatives.
Topics: Deuterium; Hydrogen; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Muramidase; Protein Conformation; Tryptophan | 1987 |
Interaction of heavy meromyosin with substrate. IV. Studies on the tyrosine and tryptophan residues by solvent perturbation method.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Chemical Phenomena; Chemistry; Deuterium; Esters; Glycerol; Glycols; Methods; Muscle Proteins; Optical Rotatory Dispersion; Phenylalanine; Solvents; Spectrophotometry; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays | 1971 |
Fractionation of native and denatured transforming deoxyribonucleic acid from Bacillus subtilis.
Topics: Arginine; Bacillus subtilis; Centrifugation, Density Gradient; Chromatography; Deuterium; DNA, Bacterial; Genetic Code; Histidine; Hot Temperature; Hydrogen; Methylation; Nitrogen; Nucleic Acid Denaturation; Radioisotopes; Serum Albumin; Silicon Dioxide; Transformation, Genetic; Tryptophan | 1968 |
Assignment of tryptophan indole NH proton resonances of lysozyme.
Topics: Animals; Chemical Phenomena; Chemistry; Chickens; Deuterium; Electron Spin Resonance Spectroscopy; Humans; Indoles; Kinetics; Muramidase; Ovalbumin; Protein Denaturation; Protons; Tryptophan; Water | 1969 |
Spin-label-induced nuclear relaxation. Distances between bound saccharides, histidine-15, and tryptophan-123 on lysozyme in solution.
Topics: Acetamides; Acetates; Binding Sites; Chemical Phenomena; Chemistry; Cyclic N-Oxides; Deuterium; Electron Spin Resonance Spectroscopy; Glucosamine; Histidine; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Models, Structural; Muramidase; Oligosaccharides; Piperidines; Protein Conformation; Tryptophan | 1972 |
Spectroscopic studies on the conformation of cytochrome c and apocytochrome c.
Topics: Animals; Apoproteins; Chemical Phenomena; Chemistry; Computers; Cytochrome c Group; Deuterium; Fluorescence; Heme; Histidine; Horses; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Myocardium; Osmolar Concentration; Protein Conformation; Protein Denaturation; Protons; Sodium Chloride; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan; Viscosity | 1974 |
Ternary complexes in solution. Bridging of the stacked adduct between tryptophan and adenosine 5'-triphosphate by zinc(II).
Topics: Adenosine Triphosphate; Binding Sites; Deuterium; Hydrogen-Ion Concentration; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Molecular Conformation; Tryptophan; Zinc | 1974 |
Excited states of biomolecules. II.
Topics: Carotenoids; Chlorophyll; Cytochromes; Deuterium; Indoles; Magnesium; Membranes, Artificial; Molecular Conformation; Photochemistry; Plants; Porphyrins; Spectrometry, Fluorescence; Tryptophan | 1974 |
Studies on the catalytic mechanism of pepsin using a new synthetic substrate.
Topics: Acetophenones; Animals; Azo Compounds; Bromine; Catalysis; Deuterium; Endopeptidases; Fluoroacetates; Glycine; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Pepsin A; Phenylalanine; Protein Binding; Structure-Activity Relationship; Swine; Tryptophan; Tyrosine | 1972 |
Direct spectrophotometric observation of an intermediate formed from deoxyadenosylcobalamin in ribonucleotide reduction.
Topics: Adenosine Triphosphate; Alcohol Oxidoreductases; Catalysis; Chemical Phenomena; Chemistry; Cobamides; Coenzymes; Cytosine Nucleotides; Deoxyribonucleotides; Deuterium; Guanine Nucleotides; Kinetics; Lactobacillus; Models, Chemical; Oxidation-Reduction; Protein Conformation; Ribonucleotides; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Temperature; Thioctic Acid; Thymine Nucleotides; Tritium; Tryptophan; Vitamin B 12 | 1973 |
Proton magnetic resonances in cytochrome b2 core. Structural similarities with cytochrome b5.
Topics: Cytochromes; Deuterium; Heme; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Saccharomyces cerevisiae; Tryptophan | 1973 |
Basis of transport discrimination of arginine from other basic amino acids in Salmonella typhimurium.
Topics: Alanine; Amino Acids; Arginine; Autoanalysis; Biological Transport; Carbon Radioisotopes; Chromatography, Ion Exchange; Deuterium; Glucose; Histidine; Homoserine; Hydroxyproline; Kinetics; Leucine; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Ornithine; Proline; Salmonella typhimurium; Structure-Activity Relationship; Tritium; Tryptophan | 1974 |
The location of tryptophanyl groups in human and bovine carbonic anhydrases. Ultraviolet difference spectra and chemical modification.
Topics: Animals; Carbonic Anhydrases; Cattle; Circular Dichroism; Crystallization; Deuterium; Dimethyl Sulfoxide; Erythrocytes; Glycerol; Glycols; Guanidines; Humans; Hydrogen-Ion Concentration; Isoenzymes; Models, Structural; Nitrobenzenes; Phenols; Polyethylenes; Protein Denaturation; Species Specificity; Spectrophotometry, Ultraviolet; Sucrose; Tryptophan; Urea | 1973 |
C-acylation of the tryptophan indole ring and its usefulness in protein chemistry.
Topics: Acetates; Acylation; Amino Acids; Anhydrides; Carboxylic Acids; Chemical Phenomena; Chemistry; Chromatography, Paper; Deuterium; Dipeptides; Fluoroacetates; Indoles; Mass Spectrometry; Muramidase; Peptides; Proteins; Pyridines; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tryptophan | 1972 |
Interaction of oligopeptides containing aromatic amino acids with nucleic acids. Fluorescence and proton magnetic resonance studies.
Topics: Adenine Nucleotides; Animals; Cattle; Deuterium; DNA; Magnetic Resonance Spectroscopy; Mathematics; Oligopeptides; Polynucleotides; Spectrometry, Fluorescence; Thymus Gland; Tryptophan; Tyrosine | 1972 |
The reaction of dimethyl(2-hydroxy-5-nitrobenzyl)sulfonium bromide with N-acetyl-L-tryptophan amide.
Topics: Acetamides; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Deuterium; Indicators and Reagents; Indoles; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nitrophenols; Onium Compounds; Piperidones; Sulfides; Tryptophan | 1973 |
Conformational changes induced by the interaction of sodium dodecyl sulfate with bovine plasma albumin.
Topics: Acetates; Animals; Cattle; Deuterium; Fatty Acids; Hydrogen-Ion Concentration; Potassium Chloride; Protein Binding; Protein Conformation; Serum Albumin, Bovine; Sodium; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Spectrophotometry; Tryptophan; Tyrosine | 1973 |
Luminescence of the tryptophan and tyrosine residues of trypsin.
Topics: Amino Acid Sequence; Binding Sites; Binding, Competitive; Deuterium; Fluorescence; Iodine Radioisotopes; Luminescent Measurements; Protein Conformation; Protein Denaturation; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature; Thermodynamics; Time Factors; Trypsin; Trypsin Inhibitors; Tryptophan; Tyrosine; Urea | 1973 |
Proton magnetic resonance assignments of the polypeptide antibiotic telomycin.
Topics: Amino Acids; Anti-Bacterial Agents; Chromatography, Thin Layer; Deuterium; Dimethyl Sulfoxide; Hydroxyproline; Magnetic Resonance Spectroscopy; Peptides; Peptides, Cyclic; Temperature; Tryptophan | 1973 |
The quenching of tyrosine and tryptophan fluorescence by H20 and D20.
Topics: Deuterium; Mathematics; Quantum Theory; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine; Water | 1973 |
13c NMR studies of the conformation of N-acetyl-L-tryptophan in its complex with chymotrypsin.
Topics: Carbodiimides; Carbon Isotopes; Chemical Phenomena; Chemistry; Chymotrypsin; Deuterium; Magnetic Resonance Spectroscopy; Mathematics; Protein Binding; Protein Conformation; Tryptophan | 1973 |
Photodynamic inactivation of lysozyme by eosin.
Topics: Animals; Binding Sites; Bromine; Chickens; Deuterium; Egg White; Fluoresceins; Hydrogen-Ion Concentration; Mathematics; Muramidase; Photochemistry; Protein Binding; Tryptophan | 1973 |
Carbon-13 NMR spectra of tryptophan, tryptophan peptides and of native and denatured proteins.
Topics: Animals; Carbon Isotopes; Cattle; Chymotrypsin; Deuterium; Dimethyl Sulfoxide; Fluoroacetates; Formates; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Indoles; Lactalbumin; Magnetic Resonance Spectroscopy; Muramidase; Peptides; Protein Conformation; Protein Denaturation; Proteins; Serum Albumin, Bovine; Tryptophan | 1973 |
Inhibition of alpha-chymotrypsin by hydroxymethyl analogues of D-and L-N-acetylphenylalanine and N-acetyltryptophan of potential affinity labeling value.
Topics: Acetates; Binding Sites; Binding, Competitive; Chromatography, Paper; Chymotrypsin; Deuterium; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methanol; Optical Rotation; Phenylalanine; Protein Binding; Spectrophotometry, Infrared; Structure-Activity Relationship; Tryptophan | 1974 |
Oxidation of amino acids by singlet oxygen. I. Comparison of dye sensitized photooxidation and microwave generated singlet oxidation.
Topics: Amino Acids; Benzyl Compounds; Deuterium; Dipeptides; Electrodes; Glycine; Histidine; Methionine; Microwaves; Oxidation-Reduction; Oxygen; Photochemistry; Tryptophan | 1974 |
Interactions of aromatic residues of proteins with nucleic acids. I. Proton magnetic resonance studies of the binding of tryptophan-containing peptides to poly(adenylic acid) and deoxyribonucleic acid.
Topics: Adenine Nucleotides; Alanine; Animals; Binding Sites; Cattle; Cold Temperature; Deuterium; DNA; Glycine; Hydrogen-Ion Concentration; Indoles; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Methyl Ethers; Nucleic Acid Conformation; Oligopeptides; Osmolar Concentration; Polynucleotides; Protons; Serotonin; Sodium Chloride; Structure-Activity Relationship; Thymus Gland; Tryptamines; Tryptophan | 1974 |
[On possible physical mechanism of thermoluminescence of certain aromatic amino acids and proteins].
Topics: Amino Acids; Chemical Phenomena; Chemistry, Physical; Cold Temperature; Deuterium; Hot Temperature; Kinetics; Luminescence; Pepsin A; Proteins; Trypsin; Tryptophan; Tyrosine; Ultraviolet Rays | 1966 |
Optical activity and solvent perturbation of fumarase.
Topics: Adipates; Animals; Circular Dichroism; Deuterium; Fumarates; Glutarates; Glycerol; Hydro-Lyases; Malonates; Myocardium; Optical Rotatory Dispersion; Osmolar Concentration; Phenylalanine; Protein Conformation; Spectrophotometry; Succinates; Swine; Tryptophan; Ultraviolet Rays | 1972 |
Spectroscopic studies on the conformation of gramicidin A'. Proton magnetic resonance assignments, coupling constants, and H-D exchange.
Topics: Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Hydrogenation; Kinetics; Leucine; Magnetic Resonance Spectroscopy; Protein Conformation; Protons; Tryptophan; Tyrothricin; Valine | 1972 |
Location of tryptophyl and tyrosyl residues in human chorionic gonadotropin.
Topics: Chorionic Gonadotropin; Deuterium; Glycols; Humans; Mercaptoethanol; Protein Conformation; Spectrophotometry; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays; Urea | 1972 |
Solvent perturbation of the tyrosyl and tryptophyl residues in subtilisin BPN'.
Topics: Chemical Phenomena; Chemistry; Circular Dichroism; Deuterium; Dimethyl Sulfoxide; Endopeptidases; Glycerol; Glycols; Optical Rotatory Dispersion; Protein Conformation; Solvents; Spectrophotometry; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays; X-Ray Diffraction | 1972 |
Proton magnetic resonance study of the indole NH resonances of lysozyme. Assignment, deuterium exchange kinetics, and inhibitor binding.
Topics: Amino Acid Sequence; Deuterium; Indoles; Kinetics; Magnetic Resonance Spectroscopy; Muramidase; Ovalbumin; Protein Binding; Protein Conformation; Protein Denaturation; Protons; Spectrophotometry; Tryptophan; X-Ray Diffraction | 1971 |
Use of chemical ionization mass spectrometry in analysis of amino acid phenylthiohydantoin derivatives formed during Edman degradation of proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Cetacea; Chromatography, Gas; Deuterium; Glutamine; Glycine; Hydantoins; Leucine; Mass Spectrometry; Methods; Myoglobin; Sulfides; Tryptophan; Valine | 1971 |
Coenzyme interactions. 3. Characteristics of the molecular complexes of thiamine with indole derivatives.
Topics: 5-Hydroxytryptophan; Chemical Phenomena; Chemistry; Coenzymes; Deuterium; Indoleacetic Acids; Indoles; Magnetic Resonance Spectroscopy; Models, Chemical; Protons; Pyrimidines; Spectrophotometry; Thiamine; Thiamine Pyrophosphate; Thiazoles; Tryptamines; Tryptophan; Ultraviolet Rays | 1969 |
Polarization of tryptophan fluorescence in muscle.
Topics: Acetates; Adenosine Triphosphate; Animals; Calcium; Chemical Phenomena; Chemistry; Deuterium; Electrochemistry; Fluorescence; Fluorometry; Glycerol; Glycols; Magnesium; Methods; Muscle Contraction; Muscle Proteins; Muscles; Myofibrils; Rabbits; Tryptophan | 1969 |
Isotopic labelling of tryptophan and tryptophan residues in polypeptides.
Topics: Deuterium; Glucagon; Peptides; Radiochemistry; Tritium; Tryptophan | 1969 |
Luminescence of the tryptophan and tyrosine residues of papain in solution.
Topics: Cold Temperature; Cysteine; Deuterium; Fluorescence; Glucose; Glycols; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Papain; Tryptophan; Tyrosine | 1970 |
Flavinyl peptides. 3. Studies of intramolecular interactions in flavinyl aromatic amino acids by proton magnetic resonance.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Esters; Flavins; Magnetic Resonance Spectroscopy; Models, Structural; Peptides; Phenylalanine; Temperature; Tryptophan; Tyrosine | 1970 |
Deuterium isotope effects on the fliorescence of tryptophan in peptides and in lysozyme.
Topics: Deuterium; Fluorescence; Models, Chemical; Muramidase; Peptides; Tryptophan | 1970 |
Proton NMR studies of hemoglobin in H2O.
Topics: Chemical Phenomena; Chemistry; Deuterium; Hemoglobins; Humans; Magnetic Resonance Spectroscopy; Protons; Tryptophan; Water | 1970 |
Laser-excited Raman spectroscopy of biomolecules. II. Native ribonuclease and alpha-chymotrypsin.
Topics: Amides; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Cystine; Deuterium; Glutamates; Histidine; Hydrogen-Ion Concentration; Lasers; Muramidase; Peptides; Phenylalanine; Protein Denaturation; Ribonucleases; Spectrum Analysis; Sulfides; Tryptophan; Tyrosine | 1970 |
Proton magnetic resonance studies of oligopeptides containing aromatic residues.
Topics: Deuterium; Dimethyl Sulfoxide; Dipeptides; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Peptides; Phenylalanine; Protein Denaturation; Proteins; Protons; Tryptophan; Tyrosine | 1971 |
The temperature-dependent conformational transitions of pyruvate kinase.
Topics: Animals; Catalysis; Chemical Phenomena; Chemistry, Physical; Deuterium; Freezing; Hydrogen-Ion Concentration; Muscles; Optical Rotatory Dispersion; Pyruvate Kinase; Rabbits; Solutions; Spectrophotometry; Temperature; Thermodynamics; Tryptophan; Ultracentrifugation; Ultraviolet Rays | 1968 |
Studies of the location of tyrosyl and tryptophyl residues in proteins. I. Solvent perturbation data of model compounds.
Topics: Deuterium; Erythritol; Glucose; Glycerol; Glycols; Indicators and Reagents; Methanol; Muramidase; Protein Denaturation; Proteins; Ribonucleases; Spectrophotometry; Sucrose; Sulfoxides; Tryptophan; Tyrosine; Urea | 1968 |
High-resolution nuclear magnetic resonance spectra of selectively deuterated staphylococcal nuclease.
Topics: Amino Acids; Asparagine; Aspartic Acid; Calcium; Deoxyribonucleases; Deuterium; Glutamates; Glutamine; Histidine; Magnetic Resonance Spectroscopy; Methionine; Nucleotides; Ribonucleases; Staphylococcus; Tryptophan; Tyrosine | 1968 |
Kinetic properties of the alpha-lytic protease of Sorangium sp., a bacterial homologue of the pancreatopeptidases.
Topics: Acetates; Amino Acid Sequence; Arginine; Bacteria; Catalysis; Chymotrypsin; Deuterium; Electrophoresis; Esters; Histidine; Hydrogen-Ion Concentration; Kinetics; Nitrophenols; Pancreatic Elastase; Peptide Hydrolases; Protease Inhibitors; Protein Binding; Serine; Spectrophotometry; Trypsin; Tryptophan; Tyrosine | 1969 |
Solvent perturbation studies of heme proteins and other colored proteins.
Topics: Animals; Catalase; Cattle; Cetacea; Cytochromes; Deuterium; Glycerol; Glycols; Heme; Hemoglobins; Horses; Hydrogen-Ion Concentration; Liver; Myoglobin; Optical Rotatory Dispersion; Solvents; Spectrum Analysis; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays; Urea; Water | 1969 |
Separation and characterization of the ovoinhibitors from chicken egg white.
Topics: Amino Acids; Animals; Chemical Phenomena; Chemistry; Chickens; Chromatography, Ion Exchange; Chymotrypsin; Deuterium; Egg White; Electrophoresis; Electrophoresis, Disc; Esterases; Glucosamine; Hexosamines; Hexoses; Molecular Weight; Neuraminic Acids; Papain; Peptides; Protease Inhibitors; Trypsin Inhibitors; Tryptophan; Ultracentrifugation | 1969 |
Role of bivalent cations in the phosphoglucomutase system. II. Metal ion binding and the structure of binary enzyme-metal complexes.
Topics: Animals; Cadmium; Cobalt; Deuterium; Dimethyl Sulfoxide; Glycols; Guanidines; Magnesium; Manganese; Nickel; Phosphoglucomutase; Propylene Glycols; Protein Binding; Rabbits; Solvents; Spectrophotometry; Spectrum Analysis; Tryptophan; Tyrosine; Ultraviolet Rays; Zinc | 1969 |
The spatial location of chromophoric residues in L-glutamate dehydrogenase.
Topics: Chemical Phenomena; Chemistry, Physical; Deuterium; Glucose; Glutamate Dehydrogenase; Glycerol; Glycols; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 1966 |
Exposure of the tryptophyl residues of metmyoglobin in solution.
Topics: Deuterium; Glycerol; Glycols; Myoglobin; Pyrrolidinones; Solutions; Spectrophotometry; Sucrose; Tryptophan | 1966 |
Studies on the identity of ordinary and deuterio-phycocyanins: end-groups, amino acid compositions, minimum molecular weights, peptide maps.
Topics: Amino Acid Sequence; Autoanalysis; Chromatography; Culture Media; Deuterium; Electrophoresis; Eukaryota; Methionine; Molecular Weight; Peptides; Pigments, Biological; Plant Proteins; Tryptophan | 1967 |
Hydrogen-deuterium exchange studies on guanidinated pig heart lactate dehydrogenase.
Topics: Animals; Arginine; Deuterium; Drug Stability; Homoarginine; Hot Temperature; Kinetics; L-Lactate Dehydrogenase; Lysine; Myocardium; Protein Conformation; Swine; Tryptophan; Tyrosine | 1983 |
Proton nuclear magnetic resonance studies of the effects of ligand binding on tryptophan residues of selectively deuterated dihydrofolate reductase from Lactobacillus casei.
Topics: Bromosuccinimide; Deuterium; Guanidines; Isotope Labeling; Lacticaseibacillus casei; Ligands; Magnetic Resonance Spectroscopy; Tetrahydrofolate Dehydrogenase; Tryptophan | 1980 |
Environment of the tryptophan residues in a myosin head: a hydrogen-deuterium exchange study.
Topics: Adenine Nucleotides; Animals; Deuterium; Hydrogen; Kinetics; Muscles; Myosin Subfragments; Myosins; Protein Binding; Rabbits; Radioisotope Dilution Technique; Spectrophotometry, Ultraviolet; Tryptophan | 1981 |
Strategies for spectral assignment in the 1H NMR spectra of a 25 000 Mr murine antibody fragment: (i) in vivo deuteration and (ii) use of a denaturant.
Topics: Animals; Binding Sites, Antibody; Chemical Phenomena; Chemistry, Physical; Deuterium; Guanidines; Immunoglobulin Variable Region; Magnetic Resonance Spectroscopy; Mice; Molecular Weight; Protein Denaturation; Tryptophan | 1981 |
Dynamics of amino acid side chains in membrane proteins by high field solid state deuterium nuclear magnetic resonance spectroscopy. Phenylalanine, tyrosine, and tryptophan.
Topics: Bacteriorhodopsins; Carotenoids; Deuterium; Halobacterium; Magnetic Resonance Spectroscopy; Membrane Proteins; Phenylalanine; Protein Conformation; Tryptophan; Tyrosine | 1981 |
Electronic spectroscopy and deuteration kinetics of tyrosine and tryptophan residues: an application to the study of erabutoxin b.
Topics: Deuterium; Elapid Venoms; Erabutoxins; Kinetics; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1980 |
2-Methyl-L-tryptophan is a substrate of tryptophanase.
Topics: Absorption; Deuterium; Escherichia coli; Indoles; Ions; Kinetics; Pyruvates; Pyruvic Acid; Quaternary Ammonium Compounds; Serine; Substrate Specificity; Tryptophan; Tryptophanase | 1995 |
Dynamics of the flexible loop of triosephosphate isomerase: the loop motion is not ligand gated.
Topics: Amino Acid Sequence; Conserved Sequence; Deuterium; Fluorescence Polarization; Glycerophosphates; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Plasmids; Protein Structure, Secondary; Recombinant Proteins; Triose-Phosphate Isomerase; Tryptophan | 1995 |
Tryptophan radicals formed by iron/oxygen reaction with Escherichia coli ribonucleotide reductase protein R2 mutant Y122F.
Topics: Amino Acid Sequence; Apoenzymes; Binding Sites; Deuterium; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Hydrogen Bonding; Iron; Models, Molecular; Oxygen; Point Mutation; Protein Conformation; Ribonucleotide Reductases; Tryptophan | 1994 |
Arabidopsis thaliana auxotrophs reveal a tryptophan-independent biosynthetic pathway for indole-3-acetic acid.
Topics: Arabidopsis; Deuterium; Gas Chromatography-Mass Spectrometry; Genotype; Indoleacetic Acids; Light; Models, Biological; Nitrogen Isotopes; ortho-Aminobenzoates; Tryptophan | 1993 |
Improved synthetic methods for the selective deuteration of aromatic amino acids: applications of selective protonation towards the identification of protein folding intermediates through nuclear magnetic resonance.
Topics: Deuterium; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Folding; Proteins; Protons; Thioredoxins; Tryptophan | 1993 |
Deuterium kinetic isotope effect and stopped-flow kinetic studies of the quinoprotein methylamine dehydrogenase.
Topics: Deuterium; Indolequinones; Isotope Labeling; Kinetics; Mathematics; Models, Theoretical; Oxidoreductases Acting on CH-NH Group Donors; Paracoccus denitrificans; Quinones; Substrate Specificity; Tryptophan | 1993 |
Role of tryptophans in substrate binding and catalysis by DNA photolyase.
Topics: Amino Acid Sequence; Apoenzymes; Aspergillus nidulans; Binding Sites; Catalysis; Chromatography; Chromatography, Affinity; Chromatography, Gel; Coenzymes; Deoxyribodipyrimidine Photo-Lyase; Deuterium; DNA Repair; Durapatite; Electron Spin Resonance Spectroscopy; Escherichia coli; Flavin-Adenine Dinucleotide; Pyrimidine Dimers; Radioisotope Dilution Technique; Riboflavin; Spectrophotometry; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Tryptophan | 1995 |
19F NMR relaxation studies on 5-fluorotryptophan- and tetradeutero-5-fluorotryptophan-labeled E. coli glucose/galactose receptor.
Topics: Anisotropy; Deuterium; Escherichia coli; Fluorine; Magnetic Resonance Spectroscopy; Receptors, Cell Surface; Tryptophan | 1996 |
Effects of alpha-deuteration and of aza and thia analogs of L-tryptophan on formation of intermediates in the reaction of Escherichia coli tryptophan indole-lyase.
Topics: Aza Compounds; Deuterium; Escherichia coli; Kinetics; Spectrophotometry; Substrate Specificity; Sulfhydryl Compounds; Tryptophan; Tryptophanase | 1996 |
Tyrosine and tryptophan structure markers in hemoglobin ultraviolet resonance Raman spectra: mode assignments via subunit-specific isotope labeling of recombinant protein.
Topics: Crystallography, X-Ray; Deuterium; Deuterium Oxide; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hemoglobins; Humans; Hydrogen Bonding; Mass Spectrometry; Models, Molecular; Protein Conformation; Recombinant Proteins; Spectrum Analysis, Raman; Tryptophan; Tyrosine | 1997 |
Raman linear intensity difference of membrane-bound peptides: indole ring orientations of tryptophans 11 and 13 in the gramicidin A transmembrane channel.
Topics: Binding Sites; Cations; Deuterium; Gramicidin; Ion Channels; Lasers; Lipid Bilayers; Models, Biological; Models, Molecular; Molecular Conformation; Protein Conformation; Sodium; Spectrum Analysis, Raman; Tryptophan; Vibration | 1998 |
Subunit-specific backbone NMR assignments of a 64 kDa trp repressor/DNA complex: a role for N-terminal residues in tandem binding.
Topics: Amino Acid Sequence; Bacterial Proteins; Carbon Isotopes; Deuterium; Dimerization; DNA-Binding Proteins; Escherichia coli; Isotope Labeling; Molecular Sequence Data; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Protein Structure, Secondary; Repressor Proteins; Tryptophan | 1998 |
Molecular ordering of interfacially localized tryptophan analogs in ester- and ether-lipid bilayers studied by 2H-NMR.
Topics: Biophysical Phenomena; Biophysics; Deuterium; Esters; Ethers; Hydrogen Bonding; Indoles; Lipid Bilayers; Magnetic Resonance Spectroscopy; Solubility; Static Electricity; Tryptophan | 1998 |
Denatured states of human carbonic anhydrase II: an NMR study of hydrogen/deuterium exchange at tryptophan-indole-H(N) sites.
Topics: Carbonic Anhydrases; Deuterium; Humans; Hydrogen; Indoles; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Denaturation; Protein Folding; Tryptophan | 1999 |
A multinuclear NMR study of the active site of an endoglucanase from a strain of Bacillus. Use of Trp residues as structural probes.
Topics: Amino Acid Sequence; Aspartic Acid; Bacillus; Binding Sites; Cellulase; Clostridium; Deuterium; Glutamic Acid; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Alignment; Tryptophan | 1999 |
Modulating dipoles for structure-function correlations in the gramicidin A channel.
Topics: Bacillus; Bacterial Proteins; Deuterium; Dimyristoylphosphatidylcholine; Gramicidin; Indoles; Ion Channels; Lipid Bilayers; Mathematical Computing; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protons; Static Electricity; Structure-Activity Relationship; Tryptophan | 1999 |
Membrane fusion induced by a short fusogenic peptide is assessed by its insertion and orientation into target bilayers.
Topics: Cholesterol; Cross-Linking Reagents; Deuterium; Kinetics; Lipid Bilayers; Liposomes; Membrane Fusion; Oligopeptides; Phosphatidylethanolamines; Phosphatidylserines; Protein Structure, Secondary; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Succinimides; Temperature; Tryptophan | 1999 |
Nicotinamide (vitamin B3) as an effective antioxidant against oxidative damage in rat brain mitochondria.
Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Buffers; Deuterium; Female; Iron; Isonicotinic Acids; Light; Lipid Peroxidation; Methylene Blue; Mitochondria; Niacinamide; Oxidative Stress; Photochemistry; Proteins; Rats; Rats, Wistar; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Tryptophan; Vitamin E | 1999 |
Probes of a role for remote binding interactions on hydrogen tunneling in the horse liver alcohol dehydrogenase reaction.
Topics: Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Binding Sites; Deuterium; Horses; Hydrogen; Isoleucine; Kinetics; Liver; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Tritium; Tryptophan | 2000 |
Hydrogen exchange at the core of Escherichia coli alkaline phosphatase studied by room-temperature tryptophan phosphorescence.
Topics: Alkaline Phosphatase; Buffers; Deuterium; Escherichia coli; Hydrogen; Kinetics; Solutions; Spectrometry, Fluorescence; Temperature; Tryptophan; Water | 2000 |
Neighboring aliphatic/aromatic side chain interactions between residues 9 and 10 in gramicidin channels.
Topics: Amino Acid Sequence; Amino Acid Substitution; Chromatography, Gel; Circular Dichroism; Deuterium; Gramicidin; Ion Channels; Leucine; Lipid Bilayers; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Protein Conformation; Tryptophan | 2000 |
Thermal unfolding of an intermediate is associated with non-Arrhenius kinetics in the folding of hen lysozyme.
Topics: Allosteric Regulation; Animals; Chickens; Circular Dichroism; Deuterium; Disulfides; Enzyme Stability; Female; Fluorescence; Hydrogen; Kinetics; Mass Spectrometry; Muramidase; Protein Denaturation; Protein Folding; Protein Renaturation; Protein Structure, Tertiary; Temperature; Thermodynamics; Tryptophan | 2000 |
Tyr115, gln165 and trp209 contribute to the 1, 2-epoxy-3-(p-nitrophenoxy)propane-conjugating activity of glutathione S-transferase cGSTM1-1.
Topics: Amino Acid Substitution; Animals; Binding Sites; Chickens; Crystallography, X-Ray; Deuterium; Epoxy Compounds; Glutamine; Glutathione; Glutathione Transferase; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Nitrophenols; Oxidoreductases; Protein Conformation; Protons; Recombinant Proteins; Structure-Activity Relationship; Temperature; Tryptophan; Tyrosine | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Methanol-induced conformations of myoglobin at pH 4.0.
Topics: Animals; Circular Dichroism; Deuterium; Horses; Hydrogen-Ion Concentration; Mass Spectrometry; Methanol; Myoglobin; Protein Conformation; Protein Denaturation; Protein Structure, Secondary; Protons; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan | 2000 |
The relative importance of tryptophan-dependent and tryptophan-independent biosynthesis of indole-3-acetic acid in tobacco during vegetative growth.
Topics: Carbon Isotopes; Crosses, Genetic; Deuterium; Indoleacetic Acids; Kinetics; Nicotiana; Plant Growth Regulators; Plants, Genetically Modified; Plants, Toxic; Protoplasts; Tryptophan | 2000 |
Probes of hydrogen tunneling with horse liver alcohol dehydrogenase at subzero temperatures.
Topics: Acetonitriles; Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Binding, Competitive; Deuterium; Dimethyl Sulfoxide; Dimethylformamide; Ethylene Glycol; Freezing; Horses; Hydrogen; Kinetics; Liver; Methanol; Phenylalanine; Propranolol; Protons; Solvents; Tryptophan | 2001 |
Differences in the pathways for unfolding and hydrogen exchange among mutants of Escherichia coli alkaline phosphatase.
Topics: Alkaline Phosphatase; Bacterial Proteins; Deuterium; Escherichia coli; Guanidine; Hydrogen; Hydrogen Bonding; Kinetics; Luminescent Measurements; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Protein Folding; Recombinant Fusion Proteins; Thermodynamics; Tryptophan | 2001 |
Assignment of the 1511 cm(-1) UV resonance Raman marker band of hemoglobin to tryptophan.
Topics: Adult; Deuterium; Hemoglobins; Humans; Hydrogen; In Vitro Techniques; Nitrogen; Spectrum Analysis, Raman; Tryptophan | 2001 |
ATR-FTIR study of the structure and orientation of transmembrane domains of the Saccharomyces cerevisiae alpha-mating factor receptor in phospholipids.
Topics: Amides; Amino Acid Sequence; Cell Membrane; Deuterium; Dimyristoylphosphatidylcholine; Lipid Bilayers; Mating Factor; Membrane Proteins; Molecular Mimicry; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphatidylglycerols; Phospholipids; Protein Structure, Secondary; Protein Structure, Tertiary; Protons; Receptors, Mating Factor; Receptors, Peptide; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Transcription Factors; Tryptophan | 2001 |
Sequence-specific assignment of histidine and tryptophan ring 1H, 13C and 15N resonances in 13C/15N- and 2H/13C/15N-labelled proteins.
Topics: Amino Acid Sequence; Anisotropy; Bacterial Proteins; Carbon Isotopes; Deuterium; Esterases; Histidine; Magnetics; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphoric Triester Hydrolases; Proteins; Protons; Tryptophan; Xylan Endo-1,3-beta-Xylosidase; Xylosidases | 2002 |
A novel method for the biosynthesis of deuterated proteins with selective protonation at the aromatic rings of Phe, Tyr and Trp.
Topics: Bacterial Proteins; Deuterium; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Proteins; Protons; Shikimic Acid; Tryptophan; Tyrosine | 2003 |
[COMPARATIVE SPECTROSCOPIC EXAMINATION OF SOME PSEUDOMELANINS FROM N-FREE SUBSTANCES. II].
Topics: Biological Products; Chemical Phenomena; Chemistry; Deuterium; Phenols; Pigments, Biological; Potassium; Pyrogallol; Quinones; Research; Spectrum Analysis; Sulfates; Tryptophan; Tyrosine | 1964 |
RADIATION CHEMISTRY OF PROTEINS. II. ENZYMIC ACTIVITY AND DEUTERIUM EXCHANGE PROPERTIES OF LYSOZYME AND ALPHA-CHYMOTRYPSIN.
Topics: Amino Acids; Cesium Isotopes; Chromatography; Chymotrypsin; Deuterium; Muramidase; Proteins; Radiation Effects; Research; Serine; Tryptophan | 1964 |
INTER- AND INTRAMOLECULAR INTERACTIONS OF ALPHA-LACTALBUMIN. IV. LOCATION OF TRYPTOPHAN GROUPS.
Topics: Albumins; Biochemical Phenomena; Biochemistry; Deuterium; Glycerol; Glycols; Hydrogen-Ion Concentration; Lactalbumin; Protein Denaturation; Research; Spectrophotometry; Sucrose; Tryptophan | 1965 |
Combined experimental/theoretical refinement of indole ring geometry using deuterium magnetic resonance and ab initio calculations.
Topics: Deuterium; Dimyristoylphosphatidylcholine; Gramicidin; Indoles; Lipid Bilayers; Membrane Proteins; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Tryptophan | 2003 |
Oxidative cross-linking of tryptophan to glycine restrains matrix metalloproteinase activity: specific structural motifs control protein oxidation.
Topics: Amino Acid Motifs; Catalytic Domain; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Deuterium; Glycine; Hydrogen; Hypochlorous Acid; Inflammation; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Matrix Metalloproteinase 7; Models, Chemical; Models, Molecular; Oxygen; Peptide Library; Peptides; Phagocytes; Spectrometry, Mass, Electrospray Ionization; Temperature; Tryptophan; Ultraviolet Rays | 2004 |
Kinetics of gas-phase hydrogen/deuterium exchange and gas-phase structure of protonated phenylalanine, proline, tyrosine and tryptophan.
Topics: Amino Acids; Computer Simulation; Cyclotrons; Deuterium; Deuterium Exchange Measurement; Gases; Hydrogen; Hydrogen Bonding; Kinetics; Models, Molecular; Phase Transition; Phenylalanine; Proline; Protein Conformation; Protons; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Tryptophan; Tyrosine | 2003 |
The catalytic and kinetic mechanisms of NADPH-dependent alkenal/one oxidoreductase.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Antioxidants; Carbon; Catalysis; Deuterium; Hydrogen; Hydrogen-Ion Concentration; Ketones; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; NADH, NADPH Oxidoreductases; NADP; Oxygen; Phylogeny; Progesterone; Protein Binding; Rats; Recombinant Proteins; Spectrometry, Fluorescence; Spectrophotometry, Atomic; Stereoisomerism; Tryptophan; Zinc | 2004 |
Probing site-specific energetics in proteins and nucleic acids by hydrogen exchange and nuclear magnetic resonance spectroscopy.
Topics: Deuterium; Deuterium Exchange Measurement; Hemoglobins; Histidine; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Nucleic Acids; Proteins; Tryptophan; Water | 2004 |
The stereospecificity and catalytic efficiency of the tryptophan synthase-catalysed exchange of the alpha-protons of amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Catalysis; Deuterium; Glycine Hydroxymethyltransferase; Hydrogen; Kinetics; Norleucine; Nuclear Magnetic Resonance, Biomolecular; Predictive Value of Tests; Protons; Serine; Stereoisomerism; Substrate Specificity; Tryptophan; Tryptophan Synthase; Valine | 2004 |
Supplementation with aromatic amino acids improves leucine kinetics but not aromatic amino acid kinetics in infants with infection, severe malnutrition, and edema.
Topics: Alanine; Amino Acids, Aromatic; Anthropometry; Body Water; Deuterium; Edema; Enteral Nutrition; Humans; Infant; Infections; Intubation, Gastrointestinal; Kinetics; Leucine; Phenylalanine; Protein-Energy Malnutrition; Proteins; Tryptophan; Tyrosine | 2004 |
Mechanistic investigation of a highly active phosphite dehydrogenase mutant and its application for NADPH regeneration.
Topics: Deuterium; Escherichia coli Proteins; Kinetics; Mutation; NAD; NADH, NADPH Oxidoreductases; NADP; Protein Structure, Tertiary; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structural Homology, Protein; Time Factors; Tryptophan; Xylitol | 2005 |
Triple-resonance methods for complete resonance assignment of aromatic protons and directly bound heteronuclei in histidine and tryptophan residues.
Topics: Amides; Amino Acids, Aromatic; Bacillus; Carbon Isotopes; Cell Cycle Proteins; Desulfovibrio vulgaris; Deuterium; Endo-1,4-beta Xylanases; Escherichia coli Proteins; Flavodoxin; Histidine; Humans; Multienzyme Complexes; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphoprotein Phosphatases; Protein Kinases; Protein Structure, Tertiary; Proteins; Protons; Recombinant Proteins; Ribonuclease T1; Tryptophan | 2005 |
Isotopic effects in the electronic spectra of tryptophan.
Topics: Deuterium; Kinetics; Molecular Structure; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics; Tryptophan | 2006 |
Electrostatic contributions to indole-lipid interactions.
Topics: Choline; Deuterium; Indoles; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phospholipids; Protons; Static Electricity; Tryptophan | 2005 |
Insights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylation.
Topics: Animals; Binding Sites; Catalysis; Deuterium; Hydroxylation; Isotopes; Kinetics; Mutation; Oxidation-Reduction; Phenylalanine; Phenylalanine Hydroxylase; Pterins; Rats; Tryptophan; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 2006 |
Helical distortion in tryptophan- and lysine-anchored membrane-spanning alpha-helices as a function of hydrophobic mismatch: a solid-state deuterium NMR investigation using the geometric analysis of labeled alanines method.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Deuterium; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Lipid Metabolism; Lysine; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Structure, Secondary; Staining and Labeling; Tryptophan | 2008 |
Selective deuteration of tryptophan and methionine residues in maltose binding protein: a model system for neutron scattering.
Topics: Carrier Proteins; Deuterium; Maltose-Binding Proteins; Methionine; Neutron Diffraction; Protein Binding; Scattering, Small Angle; Staining and Labeling; Tryptophan | 2008 |
The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels.
Topics: Chromatography, Gel; Circular Dichroism; Deuterium; Gramicidin; Ion Channels; Magnetic Resonance Spectroscopy; Membrane Proteins; Methylation; Models, Molecular; Protein Structure, Tertiary; Tryptophan | 2008 |
The biosynthetic pathway of crucifer phytoalexins and phytoanticipins: de novo incorporation of deuterated tryptophans and quasi-natural compounds.
Topics: Biological Products; Brassica napus; Deuterium; Glucosides; Indoles; Molecular Structure; Phytoalexins; Plant Roots; Plant Tubers; Sesquiterpenes; Terpenes; Tryptophan | 2009 |
Glucosylthioureidocalix[4]arenes: Synthesis, conformations and gas phase recognition of amino acids.
Topics: Amino Acids; Deuterium; Gases; Hydrogen; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Molecular Conformation; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Tryptophan; Tyrosine | 2010 |
The kinetic and solvent deuterium isotope effects in the 4- and 5-positions of the indole ring on the enzymatic decomposition of L-tryptophan.
Topics: Biocatalysis; Deuterium; Indoles; Isotope Labeling; Kinetics; Solvents; Tryptophan; Tryptophanase | 2010 |
Analysis of measured and calculated Raman spectra of indole, 3-methylindole, and tryptophan on the basis of observed and predicted isotope shifts.
Topics: Carbon Isotopes; Computer Simulation; Deuterium; Indoles; Models, Chemical; Molecular Structure; Nitrogen Isotopes; Skatole; Spectrum Analysis, Raman; Tryptophan | 2010 |
Novel approaches in selective tryptophan isotope labeling by using Escherichia coli overexpression media.
Topics: Carbon Isotopes; Deuterium; Escherichia coli; Indoles; Isotope Labeling; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Protons; Tryptophan | 2015 |
Eu(III) luminescence and tryptophan fluorescence spectroscopy as a tool for understanding interactions between hen egg white lysozyme and metal-substituted Keggin type polyoxometalates.
Topics: Animals; Buffers; Chickens; Deuterium; Europium; Female; Hydrolysis; Lactalbumin; Luminescence; Muramidase; Phosphates; Protein Binding; Spectrometry, Fluorescence; Tryptophan; Tungsten Compounds; Water | 2015 |
Synthesis of deuterium-labelled halogen derivatives of L-tryptophan catalysed by tryptophanase.
Topics: Alanine Dehydrogenase; Bacillus subtilis; Biocatalysis; Deuterium; Escherichia coli; Halogens; Isotope Labeling; Radiopharmaceuticals; Tryptophan; Tryptophanase | 2016 |
Impact of Tryptophan Oxidation in Complementarity-Determining Regions of Two Monoclonal Antibodies on Structure-Function Characterized by Hydrogen-Deuterium Exchange Mass Spectrometry and Surface Plasmon Resonance.
Topics: Antibodies, Monoclonal; Antigens; Complementarity Determining Regions; Deuterium; Deuterium Exchange Measurement; Hydrogen; Mass Spectrometry; Oxidation-Reduction; Structure-Activity Relationship; Surface Plasmon Resonance; Tryptophan | 2018 |
Deuterium-Depleted Water as Adjuvant Therapeutic Agent for Treatment of Diet-Induced Obesity in Rats.
Topics: Adjuvants, Pharmaceutic; Animals; Blood Glucose; Brain Chemistry; Cytokines; Deuterium; Diet, High-Fat; Disease Models, Animal; Male; Obesity; Oxidative Stress; Rats; Serotonin; Tryptophan; Water | 2019 |
Modular control of l-tryptophan isotopic substitution via an efficient biosynthetic cascade.
Topics: Carbon Isotopes; Deuterium; Glycine Hydroxymethyltransferase; Pyrococcus furiosus; Tryptophan; Tryptophan Synthase | 2020 |
Identification of l-Tryptophan by down-field
Topics: Brain; Deuterium; Humans; Magnetic Resonance Spectroscopy; NAD; Protons; Serotonin; Tryptophan | 2022 |
Heavy Water Reduces the Electronic Conductance of Protein Wires via Deuteron Interactions with Aromatic Residues.
Topics: Deuterium; Deuterium Oxide; Phenylalanine; Proteins; Protons; Solvents; Tryptophan | 2023 |