Page last updated: 2024-08-22

deuterium and tryptophan

deuterium has been researched along with tryptophan in 153 studies

Research

Studies (153)

TimeframeStudies, this research(%)All Research%
pre-199084 (54.90)18.7374
1990's27 (17.65)18.2507
2000's31 (20.26)29.6817
2010's8 (5.23)24.3611
2020's3 (1.96)2.80

Authors

AuthorsStudies
Nakanishi, M; Tsuboi, M1
Curtius, HC; Gitzelmann, R; Otten, A; Wegmann, H1
Beck, O; Sedvall, G; Wiesel, FA1
Moore, GR; Williams, RJ1
Grinvald, A; Pecht, I; Schlessinger, J; Steinberg, IZ1
Campbell, ID; Dobson, CM; Williams, JP1
Matthews, HR; Matthews, KS; Opella, SJ1
Nakanishi, M1
Dobson, CM; Woodworth, RC1
Curtius, HC; Redweik, U; Wegmann, H1
Bradbury, JH; Norton, RS3
Hirakwa, AY; Nakanishi, M; Takesada, H; Tsuboi, M1
Burgen, AS; Feeney, J; Griffiths, DV; Roberts, GC1
Punyiczki, M; Rosenberg, A1
Harada, I; Miura, T; Takeuchi, H2
Aubrey, KL; Thomas, GJ1
Abramson, FP; Bacher, JD; Boni, RL; Heyes, MP; Ji, XD; Markey, SP; Yergey, JA1
Backes, G; Davidson, VL; Duine, JA; Huitema, F; Sanders-Loehr, J1
Brown, KA; Farnum, MF; Howell, EE; Kraut, J; Warren, MS1
Aiba, H; Hayashi, F; Kyogoku, Y; Lee, BJ; Lee, SJ1
Amonraksa, K; Da Rin-Fioretto, S; Mammi, S; Peggion, E; Simonetti, M1
Hayashi, T; Iida, Y; Todoriki, H1
Hayashi, T; Nakane, A; Naruse, H; Takesada, M; Yamazaki, K1
Karnaukhova, E; Lugtenburg, J; Niessen, WM; Raap, J; Tjaden, UR; van der Greef, J1
Goto, Y; Hamaguchi, K; Hayashi, F; Kawata, Y; Kobayashi, Y; Kyogoku, Y1
DeHaas, GH; Jain, MK; Maliwal, BP; Slotboom, AJ1
Kiick, DM; Phillips, RS1
Abe, K; Akasaka, K; Inoue, T; Kainosho, M; Tamura, A; Watari, H1
Anglister, J; Bond, MW; Frey, T; Leahy, D; Levitt, M; McConnell, HM; Rule, GS; Tomasello, J; Whittaker, M1
Endo, T; Imoto, T; Ueda, T; Yamada, H1
Morita, F; Shimizu, T; Yagi, K1
Udenfriend, S1
Ayad, SR; Barker, GR; Weigold, J1
Glickson, JD; McDonald, CC; Phillips, WD1
McConnell, HM; Morrisett, JD; Wien, RW1
Cohen, JS; Fisher, WR; Schechter, AN1
Naumann, CF; Sigel, H1
Baba, H; Song, PS1
Hunkapiller, MW; Richards, JH1
Blakley, RL; Tamao, Y1
Groudinsky, O; Keller, R; Wüthrich, K1
Christensen, HN; Quay, S1
Lindskog, S; Nilsson, A1
Coletti-Previero, MA; Previero, A; Prota, G1
Dimicoli, JL; Helene, C2
Adam, S; Arnold, W; Heinrich, CP1
Ogura, S; Sogami, M; Uyeda, M1
Arrio, B; Hill, M; Parquet, C1
Kumar, NG; Urry, DW1
Feldman, I; McGuire, R1
Roberts, GC; Rodgers, P1
Grossweiner, LI; Kepka, AG1
Jones, JB; Lewis, AJ; Sneddon, DW1
Fischer, JR; Julian, GR; Rogers, SJ1
Kukushkin, AK; Kuznetsov, AN1
Herskovits, TT; Sorensen, ME1
Glickson, JD; Mayers, DF; Settine, JM; Urry, DW1
Mori, KF1
Fuchs, HH; Herskovits, TT1
Glickson, JD; Phillips, WD; Rupley, JA1
Brewer, HB; Bronzert, TJ; Fales, HM; Milne, GW; Nagai, Y; Pisano, JJ1
Biaglow, JE; Mieyal, JJ; Sable, HZ; Suchy, J1
Aronson, JF; Morales, MF1
Bak, B; Led, JJ; Pedersen, EJ1
Steiner, RF; Weinryb, I1
Föry, W; MacKenzie, RE; McCormick, DB; Wu, FY1
Lehrer, SS1
Fujiwara, M; Kampa, L; Patel, DJ; Shulman, RG; Yamane, T1
Lord, RC; Yu, NT1
Cohen, JS1
Kayne, FJ; Suelter, CH1
Herskovits, TT; Sorensen, M1
Jardetzky, O; Markley, JL; Putter, I1
Kaplan, H; Whitaker, DR1
Herskovits, TT1
Davis, JG; Donovan, JW; Zahnley, JC1
Peck, EJ; Ray, WJ1
Cross, DG; Fisher, HF1
Williams, EJ1
Cope, BT; Crespi, HL; Katz, JJ; Smith, U1
Abe, M; Nakanishi, M; Nosoh, Y; Tsuboi, M1
Burgen, AS; Feeney, J; Griffiths, DV; King, RW; Roberts, GC; Thomson, JW1
Nakanishi, M; Shimizu, H; Tsuboi, M; Yamada, T1
Dwek, RA; Gettins, P1
Kinsey, RA; Kintanar, A; Oldfield, E1
Kobayashi, M; Nakanishi, M; Takasaki, C; Tamiya, N; Tsuboi, M1
Belikov, VM; Dementieva, IS; Faleev, NG; Gogoleva, OI; Zakomirdina, LN1
McDermott, AE; Williams, JC1
Gräslund, A; Lassmann, G; Pötsch, S; Sahlin, M; Sjöberg, BM; Slaby, A1
Cohen, JD; Fink, GR; Normanly, J1
Richards, FM; Sykes, BD; Wishart, DS1
Brooks, HB; Davidson, VL; Jones, LH1
Heelis, PF; Kim, ST; Sancar, A1
London, RE; Luck, LA; O'Connell, TM; Vance, JE1
Phillips, RS; Sloan, MJ1
Hu, X; Spiro, TG1
Maruyama, T; Takeuchi, H1
Arrowsmith, CH; Gardner, KH; Kay, LE; Muhandiram, DR; Shan, X1
Killian, JA; Lindblom, G; Persson, S1
Jonasson, P; Jonsson, BH; Kjellsson, A; Sethson, I1
Arata, Y; Ito, S; Kawaminami, S; Shimada, I; Takahashi, H1
Busath, DD; Cotten, M; Cross, TA; Shirts, RB; Tian, C1
Hoekstra, D; Martin, I; Pécheur, EI; Ruysschaert, JM1
Devasagayam, TP; Kamat, JP1
Chin, JK; Klinman, JP1
Fischer, CJ; Gafni, A; Schauerte, JA; Steel, DG; Wisser, KC2
Andersen, OS; Greathouse, DV; Hatchett, J; Jude, AR; Koeppe, RE; Providence, LL1
Chung, EW; Dobson, CM; Jamin, M; Matagne, A; Radford, SE; Robinson, CV1
Chern, MK; Chou, CC; Hsiao, CD; Hsieh, CH; Kuan, IC; Liu, LF; Tam, MF; Wu, TC; Yeh, YH1
Ferry, JG; Tripp, BC1
Babu, KR; Douglas, DJ1
Astot, C; Crozier, A; Edlund, A; Sandberg, G; Sitbon, F1
Klinman, JP; Tsai , S1
Chen, R; Raj, V; Spiro, TG; Zhao, X1
Arshava, B; Becker, JM; Ding, FX; Naider, F; Xie, H1
Betz, M; Hartleib, J; Katsemi, V; Löhr, F; Rüterjans, H1
Ito, Y; Laue, ED; Nakayama, H; Nietlispach, D; Rajesh, S; Shibata, T; Takio, K1
CHRISTOMANOS, AA; GARDIKI, V1
HENDERSON, LE; STEVENS, CO; TOLBERT, BM1
HOLMES, LG; KRONMAN, MJ1
Greathouse, DV; Koeppe, RE; Pulay, P; Scherer, EM; Sun, H; van der Wel, PC1
Bergt, C; d'Avignon, A; Fu, X; Heinecke, JW; Huq, NP; Kao, JL; Kassim, SY; Mecham, RP; Parks, WC1
Kazazić, S; Klasinc, L; Rozman, M; Srzić, D1
Dick, RA; Kensler, TW1
Russu, IM1
Aubert, C; Brettel, K; Byrdin, M; Eker, AP; Mathis, P; Sartor, V; Vos, MH1
Malthouse, JP; Níbeilliú, ME1
Badaloo, A; Forrester, T; Heird, WC; Jahoor, F; Reid, M1
van der Donk, WA; Woodyer, R; Zhao, H1
Bernhard, F; Dötsch, V; Löhr, F; Rogov, VV; Shi, M1
Borisov, YA; Dadayan, AK; Myasoedov, NF; Zolotarev, YA1
Gaede, HC; Gawrisch, K; Yau, WM1
Fitzpatrick, PF; Pavon, JA1
Daily, AE; Greathouse, DV; Koeppe, RE; van der Wel, PC1
Callow, P; Forsyth, VT; Haertlein, M; Laux, V; Svergun, DI; Timmins, PA1
Andersen, OS; Greathouse, DV; Koeppe, RE; Sun, H1
Adio, AM; Okinyo-Owiti, DP; Pedras, MSC; Thoms, K1
Baldini, L; Casnati, A; Kalenius, E; Neitola, R; Sansone, F; Torvinen, M; Ungaro, R; Vainiotalo, P1
Dabrowski, P; Kanska, M; Winek, T; Winnicka, E1
Dieng, SD; Schelvis, JP1
Bisaccia, M; Konrat, R; Lichtenecker, RJ; Sára, T; Schmid, W; Schörghuber, J1
Absillis, G; Goovaerts, V; Parac-Vogt, TN; Stroobants, K1
Kańska, M; Szymańska, J; Winnicka, E1
Das, TK; Fu, J; Hageman, T; Kuehne, P; Leone, A; Ludwig, R; Tao, L; Wei, H; Zocher, M1
Halenova, T; Maximova, T; Pleteneva, T; Syroeshkin, A; Zlatskiy, I1
Buller, AR; Cavagnero, S; McDonald, AD; Thompson, CM; Yang, H1
Elliott, MA; Nanga, RPR; Reddy, R; Soni, ND; Swago, S; Swain, A; Wilson, N; Witschey, WR1
Afsari, S; Ghirlanda, G; Halloran, N; Lindsay, S; Mukherjee, S; Ryan, E; Wang, X1

Reviews

3 review(s) available for deuterium and tryptophan

ArticleYear
[Thermal fluctuation of protein structures (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1978, Volume: 23, Issue:12

    Topics: Animals; Cattle; Deuterium; Hot Temperature; Hydrogen; Membrane Proteins; Protein Conformation; Tryptophan

1978
Arene oxide intermediates in enzymatic hydroxylation and their significance with respect to drug toxicity.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Acetanilides; Amphetamine; Bromine; Chemical Phenomena; Chemistry; Chlorine; Deuterium; Ethers, Cyclic; Fenclonine; Fluorine; Glutathione; Mixed Function Oxygenases; Naphthalenes; Phenols; Phenylalanine; Phenylpyruvic Acids; Tritium; Tryptophan

1971
Intraprotein electron transfer and proton dynamics during photoactivation of DNA photolyase from E. coli: review and new insights from an "inverse" deuterium isotope effect.
    Biochimica et biophysica acta, 2004, Apr-12, Volume: 1655, Issue:1-3

    Topics: Deoxyribodipyrimidine Photo-Lyase; Deuterium; Electron Transport; Energy Metabolism; Escherichia coli; Kinetics; Models, Biological; Photobiology; Proton-Motive Force; Spectrophotometry; Tryptophan

2004

Trials

1 trial(s) available for deuterium and tryptophan

ArticleYear
[Metabolic changes in aromatic amino acids and monoamines in infantile autism and development of new treatment related to the finding].
    No to hattatsu = Brain and development, 1989, Volume: 21, Issue:2

    Topics: 5-Hydroxytryptophan; Amino Acids; Autistic Disorder; Biogenic Monoamines; Biopterins; Carbon Isotopes; Child; Child, Preschool; Clinical Trials as Topic; Deuterium; Double-Blind Method; Humans; Levodopa; Phenylalanine; Tryptophan

1989

Other Studies

149 other study(ies) available for deuterium and tryptophan

ArticleYear
Overall and localized fluctuation in the structure of a protein molecule.
    Advances in biophysics, 1979, Volume: 12

    Topics: Animals; Chemical Phenomena; Chemistry; Chickens; Chlorides; Deuterium; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Lithium; Muramidase; Ovalbumin; Peptides; Protein Conformation; Protein Denaturation; Proteins; Temperature; Thermodynamics; Tryptophan

1979
Nutritive value of N-acetyl-L-tryptophan in man.
    Helvetica paediatrica acta, 1979, Volume: 34, Issue:5

    Topics: Blood Proteins; Deuterium; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Nutritive Value; Tryptophan

1979
Mass fragmentographic determination of 5-hydroxytryptamine and 5-hydroxyindole-3-acetic acid in brain tissue using deuterated internal standards.
    Journal of chromatography, 1977, Apr-11, Volume: 134, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Deuterium; Fenclonine; Gas Chromatography-Mass Spectrometry; Hydroxyindoleacetic Acid; Male; Microchemistry; Pargyline; Probenecid; Rats; Reserpine; Serotonin; Tryptophan

1977
Assignment of aromatic amino acid PMR resonances of horse ferrocytochrome C.
    FEBS letters, 1975, May-15, Volume: 53, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry; Cytochrome c Group; Deuterium; Horses; Magnetic Resonance Spectroscopy; Protons; Tryptophan; Tyrosine

1975
Homogeneity and variability in the structure of azurin molecules studied by fluorescence decay and circular polarization.
    Biochemistry, 1975, May-06, Volume: 14, Issue:9

    Topics: Amides; Apoproteins; Azurin; Bacterial Proteins; Deuterium; Hydrogen-Ion Concentration; Kinetics; Mathematics; Protein Conformation; Pseudomonas aeruginosa; Quantum Theory; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan

1975
Studies of exchangeable hydrogens in lysozyme by means of Fourier transform proton magnetic resonance.
    Proceedings of the Royal Society of London. Series B, Biological sciences, 1975, Jun-17, Volume: 189, Issue:1097

    Topics: Animals; Chickens; Deuterium; Female; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Muramidase; Protein Conformation; Spectrum Analysis; Tryptophan

1975
Selectively deuterated amino acid analogues. Synthesis, incorporation into proteins and NMR properties.
    Biochimica et biophysica acta, 1977, Mar-29, Volume: 497, Issue:1

    Topics: Amino Acids; Bacterial Proteins; Chemical Phenomena; Chemistry; Deuterium; Enzyme Repression; Escherichia coli; Histidine; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Tryptophan; Tyrosine

1977
Selective substitution of 2H and 3H into aromatic amino acids catalyzed by Raney nickel.
    FEBS letters, 1979, May-15, Volume: 101, Issue:2

    Topics: Chemical Phenomena; Chemistry; Deuterium; Magnetic Resonance Spectroscopy; Nickel; Phenylalanine; Tritium; Tryptophan; Tyrosine

1979
Selective ion monitoring of tryptophan, N-acetyltryptophan and kynurenine in human serum. Application to the in vivo measurement of tryptophan pyrrolase activity.
    Journal of chromatography, 1978, Oct-01, Volume: 158

    Topics: Acetylation; Deuterium; Humans; Kynurenine; Monitoring, Physiologic; Trimethylsilyl Compounds; Tryptophan; Tryptophan Oxygenase

1978
Kinetics of hydrogen-deuterium exchange of tryptophan and tryptophan peptides in deutero-trifluoroacetic acid using proton magenetic resonance spectroscopy.
    Molecular and cellular biochemistry, 1976, Aug-30, Volume: 12, Issue:2

    Topics: Deuterium; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Oligopeptides; Protein Conformation; Temperature; Thermodynamics; Tryptophan

1976
Hydrogen-deuterium exchange of the tryptophan residues in bovine alpha-lactalbumin.
    Biopolymers, 1976, Volume: 15, Issue:10

    Topics: Animals; Deuterium; Hydrogen; In Vitro Techniques; Kinetics; Lactalbumin; Spectrum Analysis; Tryptophan

1976
Preparation of selectively deuterated aromatic amino acids for use in 1H NMR studies of proteins.
    Biochimica et biophysica acta, 1976, Oct-28, Volume: 446, Issue:2

    Topics: Deuterium; Histidine; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Tryptophan; Tyrosine

1976
Proton magnetic resonance spectroscopic studies of proteins containing deuterated tryptophan residues.
    Molecular and cellular biochemistry, 1976, Nov-30, Volume: 13, Issue:2

    Topics: Deuterium; Lactalbumin; Lactoglobulins; Magnetic Resonance Spectroscopy; Muramidase; Protein Conformation; Tryptophan

1976
The effect of viscosity on the accessibility of the single tryptophan in human serum albumin.
    Biophysical chemistry, 1992, Volume: 42, Issue:1

    Topics: Deuterium; Ethylene Glycol; Ethylene Glycols; Fluorescence; Glycerol; Humans; Hydrogen; Hydrogen-Ion Concentration; Protein Conformation; Serum Albumin; Spectrophotometry, Ultraviolet; Tryptophan; Viscosity

1992
Raman spectroscopic characterization of tryptophan side chains in lysozyme bound to inhibitors: role of the hydrophobic box in the enzymatic function.
    Biochemistry, 1991, Jun-18, Volume: 30, Issue:24

    Topics: Acetylglucosamine; Amino Acid Sequence; Animals; Chickens; Deuterium; Deuterium Oxide; Female; Hydrogen Bonding; Models, Molecular; Muramidase; Protein Binding; Protein Conformation; Spectrum Analysis, Raman; Tryptophan; Water

1991
Raman spectroscopy of filamentous bacteriophage Ff (fd, M13, f1) incorporating specifically-deuterated alanine and tryptophan side chains. Assignments and structural interpretation.
    Biophysical journal, 1991, Volume: 60, Issue:6

    Topics: Alanine; Capsid; Coliphages; Deuterium; DNA, Bacterial; DNA, Single-Stranded; DNA, Viral; Nucleic Acid Conformation; Protein Conformation; Spectrum Analysis, Raman; Tryptophan

1991
Stable isotope-labeled tryptophan as a precursor for studying the disposition of quinolinic acid in rabbits.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Deuterium; Half-Life; Kynurenine; Male; Quinolinic Acid; Quinolinic Acids; Rabbits; Tissue Distribution; Tryptophan

1991
Characterization of the tryptophan-derived quinone cofactor of methylamine dehydrogenase by resonance Raman spectroscopy.
    Biochemistry, 1991, Sep-24, Volume: 30, Issue:38

    Topics: Ammonia; Deuterium; Hydroxides; Methylamines; Motion; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Paracoccus denitrificans; Quinones; Spectrum Analysis; Spectrum Analysis, Raman; Thiobacillus; Tryptophan

1991
Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
    Biochemistry, 1991, Nov-19, Volume: 30, Issue:46

    Topics: Coenzymes; Deuterium; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Methotrexate; Mutagenesis, Site-Directed; NADP; Protein Binding; Structure-Activity Relationship; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Tryptophan

1991
A nuclear magnetic resonance study of the cyclic AMP receptor protein (CRP): assignments of the NH protons of histidine and tryptophan residues and the effect of binding of cAMP to CRP.
    Journal of biochemistry, 1990, Volume: 107, Issue:2

    Topics: Carrier Proteins; Cyclic AMP; Cyclic AMP Receptor Protein; Cyclic GMP; Deuterium; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Protein Conformation; Protons; Receptors, Cyclic AMP; Spectrum Analysis; Tryptophan

1990
Synthesis and 1H-NMR studies of alpha-deuterated analogues of des-Trp1, Nle12-human minigastrin.
    Biopolymers, 1990, Volume: 30, Issue:7-8

    Topics: Amino Acid Sequence; Deuterium; Gastrins; Glutamates; Humans; Molecular Sequence Data; Peptides; Temperature; Tryptophan

1990
Highly sensitive method for the determination of 1-methyl-1,2,3,4-tetrahydro-beta-carboline using combined capillary gas chromatography and negative-ion chemical ionization mass spectrometry.
    Journal of chromatography, 1990, Jun-08, Volume: 528, Issue:1

    Topics: Adult; Carbolines; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Male; Reference Values; Tryptamines; Tryptophan

1990
Determination of deuterium-labeled tryptophan in proteins by means of high-performance liquid chromatography and thermospray mass spectrometry.
    Analytical biochemistry, 1989, Volume: 181, Issue:2

    Topics: Amino Acids; Chromatography, High Pressure Liquid; Deuterium; Gas Chromatography-Mass Spectrometry; Halobacterium; Isothiocyanates; Isotope Labeling; Proteins; Thiocyanates; Tryptophan

1989
Hydrogen-exchange kinetics of the indole NH proton of the buried tryptophan in the constant fragment of the immunoglobulin light chain.
    Biochemistry, 1988, Jan-12, Volume: 27, Issue:1

    Topics: Bence Jones Protein; Deuterium; Humans; Hydrogen; Hydrogen-Ion Concentration; Immunoglobulin Light Chains; Kinetics; Magnetic Resonance Spectroscopy; Papain; Protein Conformation; Protein Denaturation; Protons; Tryptophan

1988
Anchoring of phospholipase A2: the effect of anions and deuterated water, and the role of N-terminus region.
    Biochimica et biophysica acta, 1986, Sep-11, Volume: 860, Issue:3

    Topics: Amino Acid Sequence; Anions; Catalysis; Deuterium; Deuterium Oxide; Glycerophospholipids; Hydrolysis; Kinetics; Lipid Bilayers; Peptide Fragments; Phosphatidic Acids; Phospholipases; Phospholipases A; Phospholipases A2; Protein Binding; Tryptophan; Water

1986
Mechanistic deductions from multiple kinetic and solvent deuterium isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Escherichia coli tryptophan indole-lyase.
    Biochemistry, 1988, Sep-20, Volume: 27, Issue:19

    Topics: Alanine; Binding, Competitive; Catalysis; Cysteine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lyases; Oxindoles; Pyridoxal Phosphate; Solvents; Tryptophan; Tryptophanase

1988
Internal motion of a tryptophan residue in Streptomyces subtilisin inhibitor: deuterium nuclear magnetic resonance in solution.
    Proteins, 1988, Volume: 4, Issue:2

    Topics: Bacterial Proteins; Deuterium; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Conformation; Subtilisins; Tryptophan

1988
Contribution of tryptophan residues to the combining site of a monoclonal anti dinitrophenyl spin-label antibody.
    Biochemistry, 1987, Sep-22, Volume: 26, Issue:19

    Topics: Amino Acid Sequence; Antibodies, Monoclonal; Base Sequence; Cloning, Molecular; Deuterium; Dinitrophenols; DNA; Haptens; Immunoglobulin Fab Fragments; Immunoglobulin Heavy Chains; Immunoglobulin Light Chains; Magnetic Resonance Spectroscopy; Protein Conformation; Radioisotope Dilution Technique; Tryptophan

1987
Characterization of individual tryptophan side chains in proteins using Raman spectroscopy and hydrogen-deuterium exchange kinetics.
    Biochemistry, 1988, Jan-12, Volume: 27, Issue:1

    Topics: Deuterium; Hydrogen; Hydrogen Bonding; Kinetics; Muramidase; Protein Conformation; Spectrum Analysis, Raman; Tryptophan

1988
pH dependence of individual tryptophan N-1 hydrogen exchange rates in lysozyme and its chemically modified derivatives.
    Biochemistry, 1987, Apr-07, Volume: 26, Issue:7

    Topics: Deuterium; Hydrogen; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Muramidase; Protein Conformation; Tryptophan

1987
Interaction of heavy meromyosin with substrate. IV. Studies on the tyrosine and tryptophan residues by solvent perturbation method.
    Journal of biochemistry, 1971, Volume: 69, Issue:3

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Chemical Phenomena; Chemistry; Deuterium; Esters; Glycerol; Glycols; Methods; Muscle Proteins; Optical Rotatory Dispersion; Phenylalanine; Solvents; Spectrophotometry; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays

1971
Fractionation of native and denatured transforming deoxyribonucleic acid from Bacillus subtilis.
    The Biochemical journal, 1968, Volume: 107, Issue:3

    Topics: Arginine; Bacillus subtilis; Centrifugation, Density Gradient; Chromatography; Deuterium; DNA, Bacterial; Genetic Code; Histidine; Hot Temperature; Hydrogen; Methylation; Nitrogen; Nucleic Acid Denaturation; Radioisotopes; Serum Albumin; Silicon Dioxide; Transformation, Genetic; Tryptophan

1968
Assignment of tryptophan indole NH proton resonances of lysozyme.
    Biochemical and biophysical research communications, 1969, May-22, Volume: 35, Issue:4

    Topics: Animals; Chemical Phenomena; Chemistry; Chickens; Deuterium; Electron Spin Resonance Spectroscopy; Humans; Indoles; Kinetics; Muramidase; Ovalbumin; Protein Denaturation; Protons; Tryptophan; Water

1969
Spin-label-induced nuclear relaxation. Distances between bound saccharides, histidine-15, and tryptophan-123 on lysozyme in solution.
    Biochemistry, 1972, Sep-26, Volume: 11, Issue:20

    Topics: Acetamides; Acetates; Binding Sites; Chemical Phenomena; Chemistry; Cyclic N-Oxides; Deuterium; Electron Spin Resonance Spectroscopy; Glucosamine; Histidine; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Models, Structural; Muramidase; Oligosaccharides; Piperidines; Protein Conformation; Tryptophan

1972
Spectroscopic studies on the conformation of cytochrome c and apocytochrome c.
    The Journal of biological chemistry, 1974, Feb-25, Volume: 249, Issue:4

    Topics: Animals; Apoproteins; Chemical Phenomena; Chemistry; Computers; Cytochrome c Group; Deuterium; Fluorescence; Heme; Histidine; Horses; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Myocardium; Osmolar Concentration; Protein Conformation; Protein Denaturation; Protons; Sodium Chloride; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan; Viscosity

1974
Ternary complexes in solution. Bridging of the stacked adduct between tryptophan and adenosine 5'-triphosphate by zinc(II).
    FEBS letters, 1974, Oct-01, Volume: 47, Issue:1

    Topics: Adenosine Triphosphate; Binding Sites; Deuterium; Hydrogen-Ion Concentration; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Molecular Conformation; Tryptophan; Zinc

1974
Excited states of biomolecules. II.
    Photochemistry and photobiology, 1974, Volume: 20, Issue:6

    Topics: Carotenoids; Chlorophyll; Cytochromes; Deuterium; Indoles; Magnesium; Membranes, Artificial; Molecular Conformation; Photochemistry; Plants; Porphyrins; Spectrometry, Fluorescence; Tryptophan

1974
Studies on the catalytic mechanism of pepsin using a new synthetic substrate.
    Biochemistry, 1972, Jul-18, Volume: 11, Issue:15

    Topics: Acetophenones; Animals; Azo Compounds; Bromine; Catalysis; Deuterium; Endopeptidases; Fluoroacetates; Glycine; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Pepsin A; Phenylalanine; Protein Binding; Structure-Activity Relationship; Swine; Tryptophan; Tyrosine

1972
Direct spectrophotometric observation of an intermediate formed from deoxyadenosylcobalamin in ribonucleotide reduction.
    Biochemistry, 1973, Jan-02, Volume: 12, Issue:1

    Topics: Adenosine Triphosphate; Alcohol Oxidoreductases; Catalysis; Chemical Phenomena; Chemistry; Cobamides; Coenzymes; Cytosine Nucleotides; Deoxyribonucleotides; Deuterium; Guanine Nucleotides; Kinetics; Lactobacillus; Models, Chemical; Oxidation-Reduction; Protein Conformation; Ribonucleotides; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Temperature; Thioctic Acid; Thymine Nucleotides; Tritium; Tryptophan; Vitamin B 12

1973
Proton magnetic resonances in cytochrome b2 core. Structural similarities with cytochrome b5.
    Biochimica et biophysica acta, 1973, Dec-06, Volume: 328, Issue:2

    Topics: Cytochromes; Deuterium; Heme; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Saccharomyces cerevisiae; Tryptophan

1973
Basis of transport discrimination of arginine from other basic amino acids in Salmonella typhimurium.
    The Journal of biological chemistry, 1974, Nov-10, Volume: 249, Issue:21

    Topics: Alanine; Amino Acids; Arginine; Autoanalysis; Biological Transport; Carbon Radioisotopes; Chromatography, Ion Exchange; Deuterium; Glucose; Histidine; Homoserine; Hydroxyproline; Kinetics; Leucine; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Ornithine; Proline; Salmonella typhimurium; Structure-Activity Relationship; Tritium; Tryptophan

1974
The location of tryptophanyl groups in human and bovine carbonic anhydrases. Ultraviolet difference spectra and chemical modification.
    Biochimica et biophysica acta, 1973, Jan-25, Volume: 295, Issue:1

    Topics: Animals; Carbonic Anhydrases; Cattle; Circular Dichroism; Crystallization; Deuterium; Dimethyl Sulfoxide; Erythrocytes; Glycerol; Glycols; Guanidines; Humans; Hydrogen-Ion Concentration; Isoenzymes; Models, Structural; Nitrobenzenes; Phenols; Polyethylenes; Protein Denaturation; Species Specificity; Spectrophotometry, Ultraviolet; Sucrose; Tryptophan; Urea

1973
C-acylation of the tryptophan indole ring and its usefulness in protein chemistry.
    Biochimica et biophysica acta, 1972, Dec-28, Volume: 285, Issue:2

    Topics: Acetates; Acylation; Amino Acids; Anhydrides; Carboxylic Acids; Chemical Phenomena; Chemistry; Chromatography, Paper; Deuterium; Dipeptides; Fluoroacetates; Indoles; Mass Spectrometry; Muramidase; Peptides; Proteins; Pyridines; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tryptophan

1972
Interaction of oligopeptides containing aromatic amino acids with nucleic acids. Fluorescence and proton magnetic resonance studies.
    FEBS letters, 1972, Oct-01, Volume: 26, Issue:1

    Topics: Adenine Nucleotides; Animals; Cattle; Deuterium; DNA; Magnetic Resonance Spectroscopy; Mathematics; Oligopeptides; Polynucleotides; Spectrometry, Fluorescence; Thymus Gland; Tryptophan; Tyrosine

1972
The reaction of dimethyl(2-hydroxy-5-nitrobenzyl)sulfonium bromide with N-acetyl-L-tryptophan amide.
    FEBS letters, 1973, Jul-01, Volume: 33, Issue:2

    Topics: Acetamides; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Deuterium; Indicators and Reagents; Indoles; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nitrophenols; Onium Compounds; Piperidones; Sulfides; Tryptophan

1973
Conformational changes induced by the interaction of sodium dodecyl sulfate with bovine plasma albumin.
    Biochimica et biophysica acta, 1973, Jun-15, Volume: 310, Issue:2

    Topics: Acetates; Animals; Cattle; Deuterium; Fatty Acids; Hydrogen-Ion Concentration; Potassium Chloride; Protein Binding; Protein Conformation; Serum Albumin, Bovine; Sodium; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Spectrophotometry; Tryptophan; Tyrosine

1973
Luminescence of the tryptophan and tyrosine residues of trypsin.
    Biochimie, 1973, Volume: 55, Issue:3

    Topics: Amino Acid Sequence; Binding Sites; Binding, Competitive; Deuterium; Fluorescence; Iodine Radioisotopes; Luminescent Measurements; Protein Conformation; Protein Denaturation; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature; Thermodynamics; Time Factors; Trypsin; Trypsin Inhibitors; Tryptophan; Tyrosine; Urea

1973
Proton magnetic resonance assignments of the polypeptide antibiotic telomycin.
    Biochemistry, 1973, Sep-25, Volume: 12, Issue:20

    Topics: Amino Acids; Anti-Bacterial Agents; Chromatography, Thin Layer; Deuterium; Dimethyl Sulfoxide; Hydroxyproline; Magnetic Resonance Spectroscopy; Peptides; Peptides, Cyclic; Temperature; Tryptophan

1973
The quenching of tyrosine and tryptophan fluorescence by H20 and D20.
    Photochemistry and photobiology, 1973, Volume: 18, Issue:2

    Topics: Deuterium; Mathematics; Quantum Theory; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine; Water

1973
13c NMR studies of the conformation of N-acetyl-L-tryptophan in its complex with chymotrypsin.
    FEBS letters, 1973, Nov-01, Volume: 36, Issue:3

    Topics: Carbodiimides; Carbon Isotopes; Chemical Phenomena; Chemistry; Chymotrypsin; Deuterium; Magnetic Resonance Spectroscopy; Mathematics; Protein Binding; Protein Conformation; Tryptophan

1973
Photodynamic inactivation of lysozyme by eosin.
    Photochemistry and photobiology, 1973, Volume: 18, Issue:1

    Topics: Animals; Binding Sites; Bromine; Chickens; Deuterium; Egg White; Fluoresceins; Hydrogen-Ion Concentration; Mathematics; Muramidase; Photochemistry; Protein Binding; Tryptophan

1973
Carbon-13 NMR spectra of tryptophan, tryptophan peptides and of native and denatured proteins.
    Biochimica et biophysica acta, 1973, Nov-11, Volume: 328, Issue:1

    Topics: Animals; Carbon Isotopes; Cattle; Chymotrypsin; Deuterium; Dimethyl Sulfoxide; Fluoroacetates; Formates; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Indoles; Lactalbumin; Magnetic Resonance Spectroscopy; Muramidase; Peptides; Protein Conformation; Protein Denaturation; Proteins; Serum Albumin, Bovine; Tryptophan

1973
Inhibition of alpha-chymotrypsin by hydroxymethyl analogues of D-and L-N-acetylphenylalanine and N-acetyltryptophan of potential affinity labeling value.
    Biochimica et biophysica acta, 1974, Mar-21, Volume: 341, Issue:1

    Topics: Acetates; Binding Sites; Binding, Competitive; Chromatography, Paper; Chymotrypsin; Deuterium; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methanol; Optical Rotation; Phenylalanine; Protein Binding; Spectrophotometry, Infrared; Structure-Activity Relationship; Tryptophan

1974
Oxidation of amino acids by singlet oxygen. I. Comparison of dye sensitized photooxidation and microwave generated singlet oxidation.
    Physiological chemistry and physics, 1974, Volume: 6, Issue:2

    Topics: Amino Acids; Benzyl Compounds; Deuterium; Dipeptides; Electrodes; Glycine; Histidine; Methionine; Microwaves; Oxidation-Reduction; Oxygen; Photochemistry; Tryptophan

1974
Interactions of aromatic residues of proteins with nucleic acids. I. Proton magnetic resonance studies of the binding of tryptophan-containing peptides to poly(adenylic acid) and deoxyribonucleic acid.
    Biochemistry, 1974, Feb-12, Volume: 13, Issue:4

    Topics: Adenine Nucleotides; Alanine; Animals; Binding Sites; Cattle; Cold Temperature; Deuterium; DNA; Glycine; Hydrogen-Ion Concentration; Indoles; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Methyl Ethers; Nucleic Acid Conformation; Oligopeptides; Osmolar Concentration; Polynucleotides; Protons; Serotonin; Sodium Chloride; Structure-Activity Relationship; Thymus Gland; Tryptamines; Tryptophan

1974
[On possible physical mechanism of thermoluminescence of certain aromatic amino acids and proteins].
    Biofizika, 1966, Volume: 11, Issue:2

    Topics: Amino Acids; Chemical Phenomena; Chemistry, Physical; Cold Temperature; Deuterium; Hot Temperature; Kinetics; Luminescence; Pepsin A; Proteins; Trypsin; Tryptophan; Tyrosine; Ultraviolet Rays

1966
Optical activity and solvent perturbation of fumarase.
    Biochimica et biophysica acta, 1972, Jan-26, Volume: 257, Issue:1

    Topics: Adipates; Animals; Circular Dichroism; Deuterium; Fumarates; Glutarates; Glycerol; Hydro-Lyases; Malonates; Myocardium; Optical Rotatory Dispersion; Osmolar Concentration; Phenylalanine; Protein Conformation; Spectrophotometry; Succinates; Swine; Tryptophan; Ultraviolet Rays

1972
Spectroscopic studies on the conformation of gramicidin A'. Proton magnetic resonance assignments, coupling constants, and H-D exchange.
    Biochemistry, 1972, Feb-15, Volume: 11, Issue:4

    Topics: Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Hydrogenation; Kinetics; Leucine; Magnetic Resonance Spectroscopy; Protein Conformation; Protons; Tryptophan; Tyrothricin; Valine

1972
Location of tryptophyl and tyrosyl residues in human chorionic gonadotropin.
    Biochimica et biophysica acta, 1972, Feb-29, Volume: 257, Issue:2

    Topics: Chorionic Gonadotropin; Deuterium; Glycols; Humans; Mercaptoethanol; Protein Conformation; Spectrophotometry; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays; Urea

1972
Solvent perturbation of the tyrosyl and tryptophyl residues in subtilisin BPN'.
    Biochimica et biophysica acta, 1972, May-18, Volume: 263, Issue:3

    Topics: Chemical Phenomena; Chemistry; Circular Dichroism; Deuterium; Dimethyl Sulfoxide; Endopeptidases; Glycerol; Glycols; Optical Rotatory Dispersion; Protein Conformation; Solvents; Spectrophotometry; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays; X-Ray Diffraction

1972
Proton magnetic resonance study of the indole NH resonances of lysozyme. Assignment, deuterium exchange kinetics, and inhibitor binding.
    Journal of the American Chemical Society, 1971, Aug-11, Volume: 93, Issue:16

    Topics: Amino Acid Sequence; Deuterium; Indoles; Kinetics; Magnetic Resonance Spectroscopy; Muramidase; Ovalbumin; Protein Binding; Protein Conformation; Protein Denaturation; Protons; Spectrophotometry; Tryptophan; X-Ray Diffraction

1971
Use of chemical ionization mass spectrometry in analysis of amino acid phenylthiohydantoin derivatives formed during Edman degradation of proteins.
    Analytical biochemistry, 1971, Volume: 43, Issue:1

    Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Cetacea; Chromatography, Gas; Deuterium; Glutamine; Glycine; Hydantoins; Leucine; Mass Spectrometry; Methods; Myoglobin; Sulfides; Tryptophan; Valine

1971
Coenzyme interactions. 3. Characteristics of the molecular complexes of thiamine with indole derivatives.
    The Journal of biological chemistry, 1969, Aug-10, Volume: 244, Issue:15

    Topics: 5-Hydroxytryptophan; Chemical Phenomena; Chemistry; Coenzymes; Deuterium; Indoleacetic Acids; Indoles; Magnetic Resonance Spectroscopy; Models, Chemical; Protons; Pyrimidines; Spectrophotometry; Thiamine; Thiamine Pyrophosphate; Thiazoles; Tryptamines; Tryptophan; Ultraviolet Rays

1969
Polarization of tryptophan fluorescence in muscle.
    Biochemistry, 1969, Volume: 8, Issue:11

    Topics: Acetates; Adenosine Triphosphate; Animals; Calcium; Chemical Phenomena; Chemistry; Deuterium; Electrochemistry; Fluorescence; Fluorometry; Glycerol; Glycols; Magnesium; Methods; Muscle Contraction; Muscle Proteins; Muscles; Myofibrils; Rabbits; Tryptophan

1969
Isotopic labelling of tryptophan and tryptophan residues in polypeptides.
    Acta chemica Scandinavica, 1969, Volume: 23, Issue:9

    Topics: Deuterium; Glucagon; Peptides; Radiochemistry; Tritium; Tryptophan

1969
Luminescence of the tryptophan and tyrosine residues of papain in solution.
    Biochemistry, 1970, Jan-06, Volume: 9, Issue:1

    Topics: Cold Temperature; Cysteine; Deuterium; Fluorescence; Glucose; Glycols; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Papain; Tryptophan; Tyrosine

1970
Flavinyl peptides. 3. Studies of intramolecular interactions in flavinyl aromatic amino acids by proton magnetic resonance.
    Biochemistry, 1970, Feb-03, Volume: 9, Issue:3

    Topics: Amino Acids; Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Esters; Flavins; Magnetic Resonance Spectroscopy; Models, Structural; Peptides; Phenylalanine; Temperature; Tryptophan; Tyrosine

1970
Deuterium isotope effects on the fliorescence of tryptophan in peptides and in lysozyme.
    Journal of the American Chemical Society, 1970, Jun-03, Volume: 92, Issue:11

    Topics: Deuterium; Fluorescence; Models, Chemical; Muramidase; Peptides; Tryptophan

1970
Proton NMR studies of hemoglobin in H2O.
    Biochemical and biophysical research communications, 1970, Sep-10, Volume: 40, Issue:5

    Topics: Chemical Phenomena; Chemistry; Deuterium; Hemoglobins; Humans; Magnetic Resonance Spectroscopy; Protons; Tryptophan; Water

1970
Laser-excited Raman spectroscopy of biomolecules. II. Native ribonuclease and alpha-chymotrypsin.
    Journal of molecular biology, 1970, Jul-28, Volume: 51, Issue:2

    Topics: Amides; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Cystine; Deuterium; Glutamates; Histidine; Hydrogen-Ion Concentration; Lasers; Muramidase; Peptides; Phenylalanine; Protein Denaturation; Ribonucleases; Spectrum Analysis; Sulfides; Tryptophan; Tyrosine

1970
Proton magnetic resonance studies of oligopeptides containing aromatic residues.
    Biochimica et biophysica acta, 1971, Mar-23, Volume: 229, Issue:3

    Topics: Deuterium; Dimethyl Sulfoxide; Dipeptides; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Peptides; Phenylalanine; Protein Denaturation; Proteins; Protons; Tryptophan; Tyrosine

1971
The temperature-dependent conformational transitions of pyruvate kinase.
    Biochemistry, 1968, Volume: 7, Issue:5

    Topics: Animals; Catalysis; Chemical Phenomena; Chemistry, Physical; Deuterium; Freezing; Hydrogen-Ion Concentration; Muscles; Optical Rotatory Dispersion; Pyruvate Kinase; Rabbits; Solutions; Spectrophotometry; Temperature; Thermodynamics; Tryptophan; Ultracentrifugation; Ultraviolet Rays

1968
Studies of the location of tyrosyl and tryptophyl residues in proteins. I. Solvent perturbation data of model compounds.
    Biochemistry, 1968, Volume: 7, Issue:7

    Topics: Deuterium; Erythritol; Glucose; Glycerol; Glycols; Indicators and Reagents; Methanol; Muramidase; Protein Denaturation; Proteins; Ribonucleases; Spectrophotometry; Sucrose; Sulfoxides; Tryptophan; Tyrosine; Urea

1968
High-resolution nuclear magnetic resonance spectra of selectively deuterated staphylococcal nuclease.
    Science (New York, N.Y.), 1968, Sep-20, Volume: 161, Issue:3847

    Topics: Amino Acids; Asparagine; Aspartic Acid; Calcium; Deoxyribonucleases; Deuterium; Glutamates; Glutamine; Histidine; Magnetic Resonance Spectroscopy; Methionine; Nucleotides; Ribonucleases; Staphylococcus; Tryptophan; Tyrosine

1968
Kinetic properties of the alpha-lytic protease of Sorangium sp., a bacterial homologue of the pancreatopeptidases.
    Canadian journal of biochemistry, 1969, Volume: 47, Issue:3

    Topics: Acetates; Amino Acid Sequence; Arginine; Bacteria; Catalysis; Chymotrypsin; Deuterium; Electrophoresis; Esters; Histidine; Hydrogen-Ion Concentration; Kinetics; Nitrophenols; Pancreatic Elastase; Peptide Hydrolases; Protease Inhibitors; Protein Binding; Serine; Spectrophotometry; Trypsin; Tryptophan; Tyrosine

1969
Solvent perturbation studies of heme proteins and other colored proteins.
    Archives of biochemistry and biophysics, 1969, Volume: 130, Issue:1

    Topics: Animals; Catalase; Cattle; Cetacea; Cytochromes; Deuterium; Glycerol; Glycols; Heme; Hemoglobins; Horses; Hydrogen-Ion Concentration; Liver; Myoglobin; Optical Rotatory Dispersion; Solvents; Spectrum Analysis; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays; Urea; Water

1969
Separation and characterization of the ovoinhibitors from chicken egg white.
    Biochemistry, 1969, Volume: 8, Issue:5

    Topics: Amino Acids; Animals; Chemical Phenomena; Chemistry; Chickens; Chromatography, Ion Exchange; Chymotrypsin; Deuterium; Egg White; Electrophoresis; Electrophoresis, Disc; Esterases; Glucosamine; Hexosamines; Hexoses; Molecular Weight; Neuraminic Acids; Papain; Peptides; Protease Inhibitors; Trypsin Inhibitors; Tryptophan; Ultracentrifugation

1969
Role of bivalent cations in the phosphoglucomutase system. II. Metal ion binding and the structure of binary enzyme-metal complexes.
    The Journal of biological chemistry, 1969, Jul-25, Volume: 244, Issue:14

    Topics: Animals; Cadmium; Cobalt; Deuterium; Dimethyl Sulfoxide; Glycols; Guanidines; Magnesium; Manganese; Nickel; Phosphoglucomutase; Propylene Glycols; Protein Binding; Rabbits; Solvents; Spectrophotometry; Spectrum Analysis; Tryptophan; Tyrosine; Ultraviolet Rays; Zinc

1969
The spatial location of chromophoric residues in L-glutamate dehydrogenase.
    Biochemistry, 1966, Volume: 5, Issue:3

    Topics: Chemical Phenomena; Chemistry, Physical; Deuterium; Glucose; Glutamate Dehydrogenase; Glycerol; Glycols; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine

1966
Exposure of the tryptophyl residues of metmyoglobin in solution.
    Archives of biochemistry and biophysics, 1966, Volume: 115, Issue:1

    Topics: Deuterium; Glycerol; Glycols; Myoglobin; Pyrrolidinones; Solutions; Spectrophotometry; Sucrose; Tryptophan

1966
Studies on the identity of ordinary and deuterio-phycocyanins: end-groups, amino acid compositions, minimum molecular weights, peptide maps.
    Biochimica et biophysica acta, 1967, Apr-11, Volume: 133, Issue:3

    Topics: Amino Acid Sequence; Autoanalysis; Chromatography; Culture Media; Deuterium; Electrophoresis; Eukaryota; Methionine; Molecular Weight; Peptides; Pigments, Biological; Plant Proteins; Tryptophan

1967
Hydrogen-deuterium exchange studies on guanidinated pig heart lactate dehydrogenase.
    Biochimica et biophysica acta, 1983, Aug-16, Volume: 746, Issue:3

    Topics: Animals; Arginine; Deuterium; Drug Stability; Homoarginine; Hot Temperature; Kinetics; L-Lactate Dehydrogenase; Lysine; Myocardium; Protein Conformation; Swine; Tryptophan; Tyrosine

1983
Proton nuclear magnetic resonance studies of the effects of ligand binding on tryptophan residues of selectively deuterated dihydrofolate reductase from Lactobacillus casei.
    Biochemistry, 1980, May-27, Volume: 19, Issue:11

    Topics: Bromosuccinimide; Deuterium; Guanidines; Isotope Labeling; Lacticaseibacillus casei; Ligands; Magnetic Resonance Spectroscopy; Tetrahydrofolate Dehydrogenase; Tryptophan

1980
Environment of the tryptophan residues in a myosin head: a hydrogen-deuterium exchange study.
    Biochemistry, 1981, Mar-03, Volume: 20, Issue:5

    Topics: Adenine Nucleotides; Animals; Deuterium; Hydrogen; Kinetics; Muscles; Myosin Subfragments; Myosins; Protein Binding; Rabbits; Radioisotope Dilution Technique; Spectrophotometry, Ultraviolet; Tryptophan

1981
Strategies for spectral assignment in the 1H NMR spectra of a 25 000 Mr murine antibody fragment: (i) in vivo deuteration and (ii) use of a denaturant.
    FEBS letters, 1981, Feb-23, Volume: 124, Issue:2

    Topics: Animals; Binding Sites, Antibody; Chemical Phenomena; Chemistry, Physical; Deuterium; Guanidines; Immunoglobulin Variable Region; Magnetic Resonance Spectroscopy; Mice; Molecular Weight; Protein Denaturation; Tryptophan

1981
Dynamics of amino acid side chains in membrane proteins by high field solid state deuterium nuclear magnetic resonance spectroscopy. Phenylalanine, tyrosine, and tryptophan.
    The Journal of biological chemistry, 1981, Sep-10, Volume: 256, Issue:17

    Topics: Bacteriorhodopsins; Carotenoids; Deuterium; Halobacterium; Magnetic Resonance Spectroscopy; Membrane Proteins; Phenylalanine; Protein Conformation; Tryptophan; Tyrosine

1981
Electronic spectroscopy and deuteration kinetics of tyrosine and tryptophan residues: an application to the study of erabutoxin b.
    Biochemistry, 1980, Jul-08, Volume: 19, Issue:14

    Topics: Deuterium; Elapid Venoms; Erabutoxins; Kinetics; Spectrometry, Fluorescence; Tryptophan; Tyrosine

1980
2-Methyl-L-tryptophan is a substrate of tryptophanase.
    Biochemistry and molecular biology international, 1995, Volume: 35, Issue:5

    Topics: Absorption; Deuterium; Escherichia coli; Indoles; Ions; Kinetics; Pyruvates; Pyruvic Acid; Quaternary Ammonium Compounds; Serine; Substrate Specificity; Tryptophan; Tryptophanase

1995
Dynamics of the flexible loop of triosephosphate isomerase: the loop motion is not ligand gated.
    Biochemistry, 1995, Jul-04, Volume: 34, Issue:26

    Topics: Amino Acid Sequence; Conserved Sequence; Deuterium; Fluorescence Polarization; Glycerophosphates; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Plasmids; Protein Structure, Secondary; Recombinant Proteins; Triose-Phosphate Isomerase; Tryptophan

1995
Tryptophan radicals formed by iron/oxygen reaction with Escherichia coli ribonucleotide reductase protein R2 mutant Y122F.
    The Journal of biological chemistry, 1994, Apr-22, Volume: 269, Issue:16

    Topics: Amino Acid Sequence; Apoenzymes; Binding Sites; Deuterium; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Hydrogen Bonding; Iron; Models, Molecular; Oxygen; Point Mutation; Protein Conformation; Ribonucleotide Reductases; Tryptophan

1994
Arabidopsis thaliana auxotrophs reveal a tryptophan-independent biosynthetic pathway for indole-3-acetic acid.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Nov-01, Volume: 90, Issue:21

    Topics: Arabidopsis; Deuterium; Gas Chromatography-Mass Spectrometry; Genotype; Indoleacetic Acids; Light; Models, Biological; Nitrogen Isotopes; ortho-Aminobenzoates; Tryptophan

1993
Improved synthetic methods for the selective deuteration of aromatic amino acids: applications of selective protonation towards the identification of protein folding intermediates through nuclear magnetic resonance.
    Biochimica et biophysica acta, 1993, Jun-24, Volume: 1164, Issue:1

    Topics: Deuterium; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Folding; Proteins; Protons; Thioredoxins; Tryptophan

1993
Deuterium kinetic isotope effect and stopped-flow kinetic studies of the quinoprotein methylamine dehydrogenase.
    Biochemistry, 1993, Mar-16, Volume: 32, Issue:10

    Topics: Deuterium; Indolequinones; Isotope Labeling; Kinetics; Mathematics; Models, Theoretical; Oxidoreductases Acting on CH-NH Group Donors; Paracoccus denitrificans; Quinones; Substrate Specificity; Tryptophan

1993
Role of tryptophans in substrate binding and catalysis by DNA photolyase.
    Methods in enzymology, 1995, Volume: 258

    Topics: Amino Acid Sequence; Apoenzymes; Aspergillus nidulans; Binding Sites; Catalysis; Chromatography; Chromatography, Affinity; Chromatography, Gel; Coenzymes; Deoxyribodipyrimidine Photo-Lyase; Deuterium; DNA Repair; Durapatite; Electron Spin Resonance Spectroscopy; Escherichia coli; Flavin-Adenine Dinucleotide; Pyrimidine Dimers; Radioisotope Dilution Technique; Riboflavin; Spectrophotometry; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Tryptophan

1995
19F NMR relaxation studies on 5-fluorotryptophan- and tetradeutero-5-fluorotryptophan-labeled E. coli glucose/galactose receptor.
    Journal of biomolecular NMR, 1996, Volume: 7, Issue:4

    Topics: Anisotropy; Deuterium; Escherichia coli; Fluorine; Magnetic Resonance Spectroscopy; Receptors, Cell Surface; Tryptophan

1996
Effects of alpha-deuteration and of aza and thia analogs of L-tryptophan on formation of intermediates in the reaction of Escherichia coli tryptophan indole-lyase.
    Biochemistry, 1996, Dec-17, Volume: 35, Issue:50

    Topics: Aza Compounds; Deuterium; Escherichia coli; Kinetics; Spectrophotometry; Substrate Specificity; Sulfhydryl Compounds; Tryptophan; Tryptophanase

1996
Tyrosine and tryptophan structure markers in hemoglobin ultraviolet resonance Raman spectra: mode assignments via subunit-specific isotope labeling of recombinant protein.
    Biochemistry, 1997, Dec-16, Volume: 36, Issue:50

    Topics: Crystallography, X-Ray; Deuterium; Deuterium Oxide; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hemoglobins; Humans; Hydrogen Bonding; Mass Spectrometry; Models, Molecular; Protein Conformation; Recombinant Proteins; Spectrum Analysis, Raman; Tryptophan; Tyrosine

1997
Raman linear intensity difference of membrane-bound peptides: indole ring orientations of tryptophans 11 and 13 in the gramicidin A transmembrane channel.
    Biospectroscopy, 1998, Volume: 4, Issue:3

    Topics: Binding Sites; Cations; Deuterium; Gramicidin; Ion Channels; Lasers; Lipid Bilayers; Models, Biological; Models, Molecular; Molecular Conformation; Protein Conformation; Sodium; Spectrum Analysis, Raman; Tryptophan; Vibration

1998
Subunit-specific backbone NMR assignments of a 64 kDa trp repressor/DNA complex: a role for N-terminal residues in tandem binding.
    Journal of biomolecular NMR, 1998, Volume: 11, Issue:3

    Topics: Amino Acid Sequence; Bacterial Proteins; Carbon Isotopes; Deuterium; Dimerization; DNA-Binding Proteins; Escherichia coli; Isotope Labeling; Molecular Sequence Data; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Protein Structure, Secondary; Repressor Proteins; Tryptophan

1998
Molecular ordering of interfacially localized tryptophan analogs in ester- and ether-lipid bilayers studied by 2H-NMR.
    Biophysical journal, 1998, Volume: 75, Issue:3

    Topics: Biophysical Phenomena; Biophysics; Deuterium; Esters; Ethers; Hydrogen Bonding; Indoles; Lipid Bilayers; Magnetic Resonance Spectroscopy; Solubility; Static Electricity; Tryptophan

1998
Denatured states of human carbonic anhydrase II: an NMR study of hydrogen/deuterium exchange at tryptophan-indole-H(N) sites.
    FEBS letters, 1999, Feb-26, Volume: 445, Issue:2-3

    Topics: Carbonic Anhydrases; Deuterium; Humans; Hydrogen; Indoles; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Denaturation; Protein Folding; Tryptophan

1999
A multinuclear NMR study of the active site of an endoglucanase from a strain of Bacillus. Use of Trp residues as structural probes.
    The Journal of biological chemistry, 1999, Jul-09, Volume: 274, Issue:28

    Topics: Amino Acid Sequence; Aspartic Acid; Bacillus; Binding Sites; Cellulase; Clostridium; Deuterium; Glutamic Acid; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Alignment; Tryptophan

1999
Modulating dipoles for structure-function correlations in the gramicidin A channel.
    Biochemistry, 1999, Jul-20, Volume: 38, Issue:29

    Topics: Bacillus; Bacterial Proteins; Deuterium; Dimyristoylphosphatidylcholine; Gramicidin; Indoles; Ion Channels; Lipid Bilayers; Mathematical Computing; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protons; Static Electricity; Structure-Activity Relationship; Tryptophan

1999
Membrane fusion induced by a short fusogenic peptide is assessed by its insertion and orientation into target bilayers.
    Biochemistry, 1999, Jul-20, Volume: 38, Issue:29

    Topics: Cholesterol; Cross-Linking Reagents; Deuterium; Kinetics; Lipid Bilayers; Liposomes; Membrane Fusion; Oligopeptides; Phosphatidylethanolamines; Phosphatidylserines; Protein Structure, Secondary; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Succinimides; Temperature; Tryptophan

1999
Nicotinamide (vitamin B3) as an effective antioxidant against oxidative damage in rat brain mitochondria.
    Redox report : communications in free radical research, 1999, Volume: 4, Issue:4

    Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Buffers; Deuterium; Female; Iron; Isonicotinic Acids; Light; Lipid Peroxidation; Methylene Blue; Mitochondria; Niacinamide; Oxidative Stress; Photochemistry; Proteins; Rats; Rats, Wistar; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Tryptophan; Vitamin E

1999
Probes of a role for remote binding interactions on hydrogen tunneling in the horse liver alcohol dehydrogenase reaction.
    Biochemistry, 2000, Feb-15, Volume: 39, Issue:6

    Topics: Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Binding Sites; Deuterium; Horses; Hydrogen; Isoleucine; Kinetics; Liver; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Tritium; Tryptophan

2000
Hydrogen exchange at the core of Escherichia coli alkaline phosphatase studied by room-temperature tryptophan phosphorescence.
    Biochemistry, 2000, Feb-15, Volume: 39, Issue:6

    Topics: Alkaline Phosphatase; Buffers; Deuterium; Escherichia coli; Hydrogen; Kinetics; Solutions; Spectrometry, Fluorescence; Temperature; Tryptophan; Water

2000
Neighboring aliphatic/aromatic side chain interactions between residues 9 and 10 in gramicidin channels.
    Biochemistry, 2000, Mar-07, Volume: 39, Issue:9

    Topics: Amino Acid Sequence; Amino Acid Substitution; Chromatography, Gel; Circular Dichroism; Deuterium; Gramicidin; Ion Channels; Leucine; Lipid Bilayers; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Protein Conformation; Tryptophan

2000
Thermal unfolding of an intermediate is associated with non-Arrhenius kinetics in the folding of hen lysozyme.
    Journal of molecular biology, 2000, Mar-17, Volume: 297, Issue:1

    Topics: Allosteric Regulation; Animals; Chickens; Circular Dichroism; Deuterium; Disulfides; Enzyme Stability; Female; Fluorescence; Hydrogen; Kinetics; Mass Spectrometry; Muramidase; Protein Denaturation; Protein Folding; Protein Renaturation; Protein Structure, Tertiary; Temperature; Thermodynamics; Tryptophan

2000
Tyr115, gln165 and trp209 contribute to the 1, 2-epoxy-3-(p-nitrophenoxy)propane-conjugating activity of glutathione S-transferase cGSTM1-1.
    Journal of molecular biology, 2000, Jul-28, Volume: 300, Issue:5

    Topics: Amino Acid Substitution; Animals; Binding Sites; Chickens; Crystallography, X-Ray; Deuterium; Epoxy Compounds; Glutamine; Glutathione; Glutathione Transferase; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Nitrophenols; Oxidoreductases; Protein Conformation; Protons; Recombinant Proteins; Structure-Activity Relationship; Temperature; Tryptophan; Tyrosine

2000
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
    Biochemistry, 2000, Aug-08, Volume: 39, Issue:31

    Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan

2000
Methanol-induced conformations of myoglobin at pH 4.0.
    Biochemistry, 2000, Nov-28, Volume: 39, Issue:47

    Topics: Animals; Circular Dichroism; Deuterium; Horses; Hydrogen-Ion Concentration; Mass Spectrometry; Methanol; Myoglobin; Protein Conformation; Protein Denaturation; Protein Structure, Secondary; Protons; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan

2000
The relative importance of tryptophan-dependent and tryptophan-independent biosynthesis of indole-3-acetic acid in tobacco during vegetative growth.
    Planta, 2000, Volume: 211, Issue:5

    Topics: Carbon Isotopes; Crosses, Genetic; Deuterium; Indoleacetic Acids; Kinetics; Nicotiana; Plant Growth Regulators; Plants, Genetically Modified; Plants, Toxic; Protoplasts; Tryptophan

2000
Probes of hydrogen tunneling with horse liver alcohol dehydrogenase at subzero temperatures.
    Biochemistry, 2001, Feb-20, Volume: 40, Issue:7

    Topics: Acetonitriles; Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Binding, Competitive; Deuterium; Dimethyl Sulfoxide; Dimethylformamide; Ethylene Glycol; Freezing; Horses; Hydrogen; Kinetics; Liver; Methanol; Phenylalanine; Propranolol; Protons; Solvents; Tryptophan

2001
Differences in the pathways for unfolding and hydrogen exchange among mutants of Escherichia coli alkaline phosphatase.
    Biochimica et biophysica acta, 2001, Feb-09, Volume: 1545, Issue:1-2

    Topics: Alkaline Phosphatase; Bacterial Proteins; Deuterium; Escherichia coli; Guanidine; Hydrogen; Hydrogen Bonding; Kinetics; Luminescent Measurements; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Protein Folding; Recombinant Fusion Proteins; Thermodynamics; Tryptophan

2001
Assignment of the 1511 cm(-1) UV resonance Raman marker band of hemoglobin to tryptophan.
    Biopolymers, 2001, Volume: 62, Issue:3

    Topics: Adult; Deuterium; Hemoglobins; Humans; Hydrogen; In Vitro Techniques; Nitrogen; Spectrum Analysis, Raman; Tryptophan

2001
ATR-FTIR study of the structure and orientation of transmembrane domains of the Saccharomyces cerevisiae alpha-mating factor receptor in phospholipids.
    Biochemistry, 2001, Jul-31, Volume: 40, Issue:30

    Topics: Amides; Amino Acid Sequence; Cell Membrane; Deuterium; Dimyristoylphosphatidylcholine; Lipid Bilayers; Mating Factor; Membrane Proteins; Molecular Mimicry; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphatidylglycerols; Phospholipids; Protein Structure, Secondary; Protein Structure, Tertiary; Protons; Receptors, Mating Factor; Receptors, Peptide; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Transcription Factors; Tryptophan

2001
Sequence-specific assignment of histidine and tryptophan ring 1H, 13C and 15N resonances in 13C/15N- and 2H/13C/15N-labelled proteins.
    Journal of biomolecular NMR, 2002, Volume: 22, Issue:2

    Topics: Amino Acid Sequence; Anisotropy; Bacterial Proteins; Carbon Isotopes; Deuterium; Esterases; Histidine; Magnetics; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphoric Triester Hydrolases; Proteins; Protons; Tryptophan; Xylan Endo-1,3-beta-Xylosidase; Xylosidases

2002
A novel method for the biosynthesis of deuterated proteins with selective protonation at the aromatic rings of Phe, Tyr and Trp.
    Journal of biomolecular NMR, 2003, Volume: 27, Issue:1

    Topics: Bacterial Proteins; Deuterium; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Proteins; Protons; Shikimic Acid; Tryptophan; Tyrosine

2003
[COMPARATIVE SPECTROSCOPIC EXAMINATION OF SOME PSEUDOMELANINS FROM N-FREE SUBSTANCES. II].
    Enzymologia, 1964, May-15, Volume: 27

    Topics: Biological Products; Chemical Phenomena; Chemistry; Deuterium; Phenols; Pigments, Biological; Potassium; Pyrogallol; Quinones; Research; Spectrum Analysis; Sulfates; Tryptophan; Tyrosine

1964
RADIATION CHEMISTRY OF PROTEINS. II. ENZYMIC ACTIVITY AND DEUTERIUM EXCHANGE PROPERTIES OF LYSOZYME AND ALPHA-CHYMOTRYPSIN.
    Archives of biochemistry and biophysics, 1964, Volume: 107

    Topics: Amino Acids; Cesium Isotopes; Chromatography; Chymotrypsin; Deuterium; Muramidase; Proteins; Radiation Effects; Research; Serine; Tryptophan

1964
INTER- AND INTRAMOLECULAR INTERACTIONS OF ALPHA-LACTALBUMIN. IV. LOCATION OF TRYPTOPHAN GROUPS.
    Biochemistry, 1965, Volume: 4

    Topics: Albumins; Biochemical Phenomena; Biochemistry; Deuterium; Glycerol; Glycols; Hydrogen-Ion Concentration; Lactalbumin; Protein Denaturation; Research; Spectrophotometry; Sucrose; Tryptophan

1965
Combined experimental/theoretical refinement of indole ring geometry using deuterium magnetic resonance and ab initio calculations.
    Journal of the American Chemical Society, 2003, Oct-08, Volume: 125, Issue:40

    Topics: Deuterium; Dimyristoylphosphatidylcholine; Gramicidin; Indoles; Lipid Bilayers; Membrane Proteins; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Tryptophan

2003
Oxidative cross-linking of tryptophan to glycine restrains matrix metalloproteinase activity: specific structural motifs control protein oxidation.
    The Journal of biological chemistry, 2004, Feb-20, Volume: 279, Issue:8

    Topics: Amino Acid Motifs; Catalytic Domain; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Deuterium; Glycine; Hydrogen; Hypochlorous Acid; Inflammation; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Matrix Metalloproteinase 7; Models, Chemical; Models, Molecular; Oxygen; Peptide Library; Peptides; Phagocytes; Spectrometry, Mass, Electrospray Ionization; Temperature; Tryptophan; Ultraviolet Rays

2004
Kinetics of gas-phase hydrogen/deuterium exchange and gas-phase structure of protonated phenylalanine, proline, tyrosine and tryptophan.
    Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:24

    Topics: Amino Acids; Computer Simulation; Cyclotrons; Deuterium; Deuterium Exchange Measurement; Gases; Hydrogen; Hydrogen Bonding; Kinetics; Models, Molecular; Phase Transition; Phenylalanine; Proline; Protein Conformation; Protons; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Tryptophan; Tyrosine

2003
The catalytic and kinetic mechanisms of NADPH-dependent alkenal/one oxidoreductase.
    The Journal of biological chemistry, 2004, Apr-23, Volume: 279, Issue:17

    Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Antioxidants; Carbon; Catalysis; Deuterium; Hydrogen; Hydrogen-Ion Concentration; Ketones; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; NADH, NADPH Oxidoreductases; NADP; Oxygen; Phylogeny; Progesterone; Protein Binding; Rats; Recombinant Proteins; Spectrometry, Fluorescence; Spectrophotometry, Atomic; Stereoisomerism; Tryptophan; Zinc

2004
Probing site-specific energetics in proteins and nucleic acids by hydrogen exchange and nuclear magnetic resonance spectroscopy.
    Methods in enzymology, 2004, Volume: 379

    Topics: Deuterium; Deuterium Exchange Measurement; Hemoglobins; Histidine; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Nucleic Acids; Proteins; Tryptophan; Water

2004
The stereospecificity and catalytic efficiency of the tryptophan synthase-catalysed exchange of the alpha-protons of amino acids.
    The Biochemical journal, 2004, Aug-01, Volume: 381, Issue:Pt 3

    Topics: Alanine; Amino Acids; Aminobutyrates; Catalysis; Deuterium; Glycine Hydroxymethyltransferase; Hydrogen; Kinetics; Norleucine; Nuclear Magnetic Resonance, Biomolecular; Predictive Value of Tests; Protons; Serine; Stereoisomerism; Substrate Specificity; Tryptophan; Tryptophan Synthase; Valine

2004
Supplementation with aromatic amino acids improves leucine kinetics but not aromatic amino acid kinetics in infants with infection, severe malnutrition, and edema.
    The Journal of nutrition, 2004, Volume: 134, Issue:11

    Topics: Alanine; Amino Acids, Aromatic; Anthropometry; Body Water; Deuterium; Edema; Enteral Nutrition; Humans; Infant; Infections; Intubation, Gastrointestinal; Kinetics; Leucine; Phenylalanine; Protein-Energy Malnutrition; Proteins; Tryptophan; Tyrosine

2004
Mechanistic investigation of a highly active phosphite dehydrogenase mutant and its application for NADPH regeneration.
    The FEBS journal, 2005, Volume: 272, Issue:15

    Topics: Deuterium; Escherichia coli Proteins; Kinetics; Mutation; NAD; NADH, NADPH Oxidoreductases; NADP; Protein Structure, Tertiary; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structural Homology, Protein; Time Factors; Tryptophan; Xylitol

2005
Triple-resonance methods for complete resonance assignment of aromatic protons and directly bound heteronuclei in histidine and tryptophan residues.
    Journal of biomolecular NMR, 2005, Volume: 32, Issue:4

    Topics: Amides; Amino Acids, Aromatic; Bacillus; Carbon Isotopes; Cell Cycle Proteins; Desulfovibrio vulgaris; Deuterium; Endo-1,4-beta Xylanases; Escherichia coli Proteins; Flavodoxin; Histidine; Humans; Multienzyme Complexes; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphoprotein Phosphatases; Protein Kinases; Protein Structure, Tertiary; Proteins; Protons; Recombinant Proteins; Ribonuclease T1; Tryptophan

2005
Isotopic effects in the electronic spectra of tryptophan.
    Amino acids, 2006, Volume: 31, Issue:4

    Topics: Deuterium; Kinetics; Molecular Structure; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics; Tryptophan

2006
Electrostatic contributions to indole-lipid interactions.
    The journal of physical chemistry. B, 2005, Jul-07, Volume: 109, Issue:26

    Topics: Choline; Deuterium; Indoles; Lipid Bilayers; Magnetic Resonance Spectroscopy; Phospholipids; Protons; Static Electricity; Tryptophan

2005
Insights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylation.
    Biochemistry, 2006, Sep-12, Volume: 45, Issue:36

    Topics: Animals; Binding Sites; Catalysis; Deuterium; Hydroxylation; Isotopes; Kinetics; Mutation; Oxidation-Reduction; Phenylalanine; Phenylalanine Hydroxylase; Pterins; Rats; Tryptophan; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

2006
Helical distortion in tryptophan- and lysine-anchored membrane-spanning alpha-helices as a function of hydrophobic mismatch: a solid-state deuterium NMR investigation using the geometric analysis of labeled alanines method.
    Biophysical journal, 2008, Jan-15, Volume: 94, Issue:2

    Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Deuterium; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Lipid Metabolism; Lysine; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Structure, Secondary; Staining and Labeling; Tryptophan

2008
Selective deuteration of tryptophan and methionine residues in maltose binding protein: a model system for neutron scattering.
    European biophysics journal : EBJ, 2008, Volume: 37, Issue:6

    Topics: Carrier Proteins; Deuterium; Maltose-Binding Proteins; Methionine; Neutron Diffraction; Protein Binding; Scattering, Small Angle; Staining and Labeling; Tryptophan

2008
The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels.
    The Journal of biological chemistry, 2008, Aug-08, Volume: 283, Issue:32

    Topics: Chromatography, Gel; Circular Dichroism; Deuterium; Gramicidin; Ion Channels; Magnetic Resonance Spectroscopy; Membrane Proteins; Methylation; Models, Molecular; Protein Structure, Tertiary; Tryptophan

2008
The biosynthetic pathway of crucifer phytoalexins and phytoanticipins: de novo incorporation of deuterated tryptophans and quasi-natural compounds.
    Phytochemistry, 2009, Volume: 70, Issue:9

    Topics: Biological Products; Brassica napus; Deuterium; Glucosides; Indoles; Molecular Structure; Phytoalexins; Plant Roots; Plant Tubers; Sesquiterpenes; Terpenes; Tryptophan

2009
Glucosylthioureidocalix[4]arenes: Synthesis, conformations and gas phase recognition of amino acids.
    Organic & biomolecular chemistry, 2010, Feb-21, Volume: 8, Issue:4

    Topics: Amino Acids; Deuterium; Gases; Hydrogen; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Molecular Conformation; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Tryptophan; Tyrosine

2010
The kinetic and solvent deuterium isotope effects in the 4- and 5-positions of the indole ring on the enzymatic decomposition of L-tryptophan.
    Isotopes in environmental and health studies, 2010, Volume: 46, Issue:2

    Topics: Biocatalysis; Deuterium; Indoles; Isotope Labeling; Kinetics; Solvents; Tryptophan; Tryptophanase

2010
Analysis of measured and calculated Raman spectra of indole, 3-methylindole, and tryptophan on the basis of observed and predicted isotope shifts.
    The journal of physical chemistry. A, 2010, Oct-14, Volume: 114, Issue:40

    Topics: Carbon Isotopes; Computer Simulation; Deuterium; Indoles; Models, Chemical; Molecular Structure; Nitrogen Isotopes; Skatole; Spectrum Analysis, Raman; Tryptophan

2010
Novel approaches in selective tryptophan isotope labeling by using Escherichia coli overexpression media.
    Chembiochem : a European journal of chemical biology, 2015, Mar-23, Volume: 16, Issue:5

    Topics: Carbon Isotopes; Deuterium; Escherichia coli; Indoles; Isotope Labeling; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Protons; Tryptophan

2015
Eu(III) luminescence and tryptophan fluorescence spectroscopy as a tool for understanding interactions between hen egg white lysozyme and metal-substituted Keggin type polyoxometalates.
    Journal of inorganic biochemistry, 2015, Volume: 150

    Topics: Animals; Buffers; Chickens; Deuterium; Europium; Female; Hydrolysis; Lactalbumin; Luminescence; Muramidase; Phosphates; Protein Binding; Spectrometry, Fluorescence; Tryptophan; Tungsten Compounds; Water

2015
Synthesis of deuterium-labelled halogen derivatives of L-tryptophan catalysed by tryptophanase.
    Isotopes in environmental and health studies, 2016, Volume: 52, Issue:3

    Topics: Alanine Dehydrogenase; Bacillus subtilis; Biocatalysis; Deuterium; Escherichia coli; Halogens; Isotope Labeling; Radiopharmaceuticals; Tryptophan; Tryptophanase

2016
Impact of Tryptophan Oxidation in Complementarity-Determining Regions of Two Monoclonal Antibodies on Structure-Function Characterized by Hydrogen-Deuterium Exchange Mass Spectrometry and Surface Plasmon Resonance.
    Pharmaceutical research, 2018, Dec-10, Volume: 36, Issue:1

    Topics: Antibodies, Monoclonal; Antigens; Complementarity Determining Regions; Deuterium; Deuterium Exchange Measurement; Hydrogen; Mass Spectrometry; Oxidation-Reduction; Structure-Activity Relationship; Surface Plasmon Resonance; Tryptophan

2018
Deuterium-Depleted Water as Adjuvant Therapeutic Agent for Treatment of Diet-Induced Obesity in Rats.
    Molecules (Basel, Switzerland), 2019, Dec-19, Volume: 25, Issue:1

    Topics: Adjuvants, Pharmaceutic; Animals; Blood Glucose; Brain Chemistry; Cytokines; Deuterium; Diet, High-Fat; Disease Models, Animal; Male; Obesity; Oxidative Stress; Rats; Serotonin; Tryptophan; Water

2019
Modular control of l-tryptophan isotopic substitution via an efficient biosynthetic cascade.
    Organic & biomolecular chemistry, 2020, 06-10, Volume: 18, Issue:22

    Topics: Carbon Isotopes; Deuterium; Glycine Hydroxymethyltransferase; Pyrococcus furiosus; Tryptophan; Tryptophan Synthase

2020
Identification of l-Tryptophan by down-field
    Magnetic resonance in medicine, 2022, Volume: 88, Issue:6

    Topics: Brain; Deuterium; Humans; Magnetic Resonance Spectroscopy; NAD; Protons; Serotonin; Tryptophan

2022
Heavy Water Reduces the Electronic Conductance of Protein Wires via Deuteron Interactions with Aromatic Residues.
    Nano letters, 2023, 10-11, Volume: 23, Issue:19

    Topics: Deuterium; Deuterium Oxide; Phenylalanine; Proteins; Protons; Solvents; Tryptophan

2023