deuterium has been researched along with thiazoles in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (53.85) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 8 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| White, RH | 1 |
| Krishna, G; Pohl, LR | 1 |
| Burnett, D; Frearson, MJ; Offen, CP; Wilson, K | 1 |
| Carlin, JR; Ellsworth, RL; VandenHeuvel, WJ; Walker, RW; Wolf, FJ | 1 |
| Briand, C; Chauvet-Monges, AM; Crevat, A; Rogeret, C | 1 |
| Krampitz, LO | 1 |
| Biaglow, JE; Mieyal, JJ; Sable, HZ; Suchy, J | 1 |
| Crosby, J; Lienhard, GE | 1 |
| Hirotsu, Y; Kaneko, T; Shiba, T | 1 |
| Hübner, G; Kolbe, A; Schellenberger, A | 1 |
| Estramareix, B; Fischer, JC; Thérisod, M | 1 |
| Anders, MW; Stevens, JL | 1 |
| Augustine, AM; Begley, TP; Dorrestein, PC; Ealick, SE; Park, JH; Settembre, EC | 1 |
| HANAI, K; MACHIDA, K; SASAKI, S; UEDA, M; UNO, T | 1 |
| COLLIN, RL; PULLMAN, B | 1 |
| Kamel, A; Miao, Z; Prakash, C | 1 |
| Carter, SA; Coleman, C; Grover, RK; Ionescu-Zanetti, C; Khurana, R; Krishna, V; Roy, R; Singh, S | 1 |
| Binger, KJ; Gooley, PR; Griffin, MD; Howlett, GJ; Lin, F; Mertens, HD; Mok, YF; Wade, JD; Wilson, LM | 1 |
| Engler, H; Gambini, JP; Kilander, L; Långström, B; Lannfelt, L; Santillo, AF; Ulla-Marja, L | 1 |
| Almkvist, O; Carter, SF; Engler, H; Långström, B; Nordberg, A; Schöll, M; Wall, A | 1 |
| Cao, B; Chen, G; Chu, A; Han, K; Ling, C; Mao, X; Yin, J; Zhang, Z; Zhao, Y | 1 |
| Gerhardt, D; Hopf, C; Matheis, K; Meyer, B; Schubach, B; Schulz, S; Seegel, M | 1 |
| Li, S; Macartney, DH; Wang, R; Wyman, IW; Yin, H; Zhang, Q | 1 |
| Almkvist, O; Carter, SF; Chiotis, K; Långström, B; Leuzy, A; Nordberg, A; Rodriguez-Vieitez, E; Saint-Aubert, L; Schöll, M; Wall, A | 1 |
| Aichholz, R; Blanz, J; Blasco, F; Caravatti, G; Fairhurst, RA; Fritsch, C; Guagnano, V; Maira, SM; Schnell, C; Seiler, FH; Wipfli, P | 1 |
| Chen, C; Chen, F; Chen, P; Kong, Y; Ren, S; Song, H; Sun, H; Xu, Q | 1 |
1 review(s) available for deuterium and thiazoles
| Article | Year |
|---|---|
Catalytic functions of thiamin diphosphate.
Topics: Aldehyde-Lyases; Animals; Bacteria; Butanones; Carbohydrates; Carbon Isotopes; Carboxy-Lyases; Catalysis; Chemical Phenomena; Chemistry; Deuterium; Glyoxylates; Pyruvate Oxidase; Pyruvates; Tartronates; Thiamine Pyrophosphate; Thiazoles; Transferases | 1969 |
25 other study(ies) available for deuterium and thiazoles
| Article | Year |
|---|---|
Stable isotope studies on the biosynthesis of the thiazole moiety of thiamin in Escherichia coli.
Topics: Carbon Isotopes; Deuterium; Escherichia coli; Isotope Labeling; Thiamine; Thiazoles | 1978 |
Deuterium isotope effect in bioactivation and hepatotoxicity of chloroform.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Cysteine; Cytochrome P-450 Enzyme System; Deuterium; Male; Microsomes, Liver; Phenobarbital; Rats; Thiazoles | 1978 |
4,5-Dimethylthiazole-N-oxide-S-oxide: a metabolite of chlormethiazole in man.
Topics: Chemical Phenomena; Chemistry; Chlormethiazole; Chromatography, Gas; Deuterium; Humans; Male; Mass Spectrometry; Oxidation-Reduction; Thiazoles; Titanium; Trimethylsilyl Compounds | 1985 |
Source of the carboxamide nitrogen atom in 2-carboxamido-5-isopropoxycarbonylaminobenz-imidazole, a metabolite of cambendazole.
Topics: Amides; Aniline Compounds; Animals; Anthelmintics; Benzimidazoles; Carbon Radioisotopes; Chromatography, Gas; Chromatography, Thin Layer; Deuterium; Drug Stability; Mass Spectrometry; Nitrogen; Nitrogen Isotopes; Rats; Thiazoles | 1974 |
NMR study of the lability of the thiazolium proton in thiamin and its polyphosphoric esters.
Topics: Deuterium; Half-Life; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Protons; Structure-Activity Relationship; Thiamine; Thiamine Pyrophosphate; Thiazoles | 1973 |
Coenzyme interactions. 3. Characteristics of the molecular complexes of thiamine with indole derivatives.
Topics: 5-Hydroxytryptophan; Chemical Phenomena; Chemistry; Coenzymes; Deuterium; Indoleacetic Acids; Indoles; Magnetic Resonance Spectroscopy; Models, Chemical; Protons; Pyrimidines; Spectrophotometry; Thiamine; Thiamine Pyrophosphate; Thiazoles; Tryptamines; Tryptophan; Ultraviolet Rays | 1969 |
Mechanisms of thiamine-catalyzed reactions. A kinetic analysis of the decarboxylation of pyruvate by 3,4-dimethylthiazolium ion in water and ethanol.
Topics: Catalysis; Deuterium; Ethanol; Hydrogen; Kinetics; Pyruvates; Thiamine; Thiazoles; Water | 1970 |
Synthesis of the thiazoline derivative of glutathione.
Topics: Chemical Phenomena; Chemistry; Deuterium; Glutathione; Imines; Thiazoles | 1970 |
[On the theory of cocarboxylase action. I. Influence of pH, N-position residue and metal ions on CH-acidity of thiazolium salts].
Topics: Buffers; Chemical Phenomena; Chemistry; Copper; Deuterium; Hydrogen-Ion Concentration; Magnesium; Manganese; Spectrum Analysis; Thiamine Pyrophosphate; Thiazoles; Zinc | 1965 |
The origin of the carbon chain in the thiazole moiety of thiamine in Escherichia coli: incorporation of deuterated 1-deoxy-D-threo-2-pentulose.
Topics: Deoxy Sugars; Deuterium; Escherichia coli; Isotope Labeling; Mass Spectrometry; Pentoses; Thiamine; Thiazoles; Xylulose | 1981 |
Metabolism of haloforms to carbon monoxide. IV. studies on the reaction mechanism in vivo.
Topics: Animals; Carbon Monoxide; Carcinogens; Chloroform; Cysteine; Deuterium; Hydrocarbons, Brominated; Male; Maleates; Phenobarbital; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Trihalomethanes | 1981 |
Structural and mechanistic studies on ThiO, a glycine oxidase essential for thiamin biosynthesis in Bacillus subtilis.
Topics: Amino Acid Oxidoreductases; Bacillus subtilis; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Deuterium; Flavin-Adenine Dinucleotide; Flavins; Flavoproteins; Kinetics; Mutation; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Protein Structure, Quaternary; Protein Structure, Tertiary; Stereoisomerism; Substrate Specificity; Thiamine; Thiazoles | 2003 |
INFRARED SPECTRA OF SULFONAMIDE DERIVATIVES. I. PYRIDINE, THIAZOLE, AND PYRIMIDINE DERIVATIVES.
Topics: Chemistry, Pharmaceutical; Deuterium; Pyridines; Pyrimidines; Research; Spectrum Analysis; Sulfathiazoles; Sulfonamides; Thiazoles | 1963 |
SOME ELECTRONIC ASPECTS OF THE MECHANISM OF THIAMINE ACTION.
Topics: Catalysis; Chemical Phenomena; Chemistry; Deuterium; Electrons; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Oxazoles; Research; Sulfur; Thiamine; Thiazoles | 1964 |
Characterization of a novel metabolite intermediate of ziprasidone in hepatic cytosolic fractions of rat, dog, and human by ESI-MS/MS, hydrogen/deuterium exchange, and chemical derivatization.
Topics: Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytosol; Deuterium; Dogs; Humans; Hydrogen; Liver; Piperazines; Rats; Spectrometry, Mass, Electrospray Ionization; Thiazoles | 2005 |
Mechanism of thioflavin T binding to amyloid fibrils.
Topics: Amyloid; Benzothiazoles; Binding Sites; Deuterium; Fluorescence; Fluorescence Polarization; Fluorescent Dyes; Hydrogen-Ion Concentration; Micelles; Microscopy, Atomic Force; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Solutions; Spectroscopy, Fourier Transform Infrared; Thiazoles; Water | 2005 |
A structural core within apolipoprotein C-II amyloid fibrils identified using hydrogen exchange and proteolysis.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amyloid; Apolipoprotein C-II; Benzothiazoles; Chromatography, High Pressure Liquid; Circular Dichroism; Deuterium; Deuterium Exchange Measurement; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Endopeptidase K; Fluorescent Dyes; Humans; Hydrogen; Hydrolysis; Kinetics; Mass Spectrometry; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Serine Endopeptidases; Spectrometry, Fluorescence; Thiazoles; Time Factors; Trypsin | 2007 |
In vivo imaging of astrocytosis in Alzheimer's disease: an ¹¹C-L-deuteriodeprenyl and PIB PET study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aniline Compounds; Brain; Carbon Radioisotopes; Deuterium; Female; Gliosis; Humans; Positron-Emission Tomography; Radiopharmaceuticals; Selegiline; Thiazoles; Tissue Distribution | 2011 |
Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Brain; Case-Control Studies; Cognitive Dysfunction; Deuterium; Female; Fluorodeoxyglucose F18; Gliosis; Humans; Male; Middle Aged; Monoamine Oxidase; Neuropsychological Tests; Positron-Emission Tomography; Radioactive Tracers; Retrospective Studies; Selegiline; Thiazoles | 2012 |
A deuterated analog of dasatinib disrupts cell cycle progression and displays anti-non-small cell lung cancer activity in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Dasatinib; Deuterium; Enzyme Activation; Humans; Lung Neoplasms; Mice; Mice, Nude; Pyrimidines; Signal Transduction; src-Family Kinases; Thiazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
DMSO-enhanced MALDI MS imaging with normalization against a deuterated standard for relative quantification of dasatinib in serial mouse pharmacology studies.
Topics: Animals; Dasatinib; Deuterium; Female; Isotope Labeling; Kidney; Mice; Mice, Inbred C57BL; Pyrimidines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles | 2013 |
Encapsulation of Vitamin B(1) and Its Phosphate Derivatives by Cucurbit[7]uril: Tunability of the Binding Site and Affinity by the Presence of Phosphate Groups.
Topics: Bridged-Ring Compounds; Deuterium; Imidazoles; Magnetic Resonance Spectroscopy; Phosphates; Pyrimidines; Thiamine; Thiazoles | 2016 |
Comparison of Early-Phase 11C-Deuterium-l-Deprenyl and 11C-Pittsburgh Compound B PET for Assessing Brain Perfusion in Alzheimer Disease.
Topics: Aged; Alzheimer Disease; Aniline Compounds; Cerebellum; Cerebrovascular Circulation; Cognitive Dysfunction; Deuterium; Diagnosis, Differential; Female; Fluorodeoxyglucose F18; Gliosis; Gray Matter; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Perfusion; Pons; Positron-Emission Tomography; Radiopharmaceuticals; Selegiline; Thiazoles | 2016 |
Increasing metabolic stability via the deuterium kinetic isotope effect: An example from a proline-amide-urea aminothiazole series of phosphatidylinositol-3 kinase alpha inhibitors.
Topics: Amides; Animals; Biological Availability; Class I Phosphatidylinositol 3-Kinases; Deuterium; Enzyme Inhibitors; Kinetics; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proline; Rats; Thiazoles; Urea | 2016 |
Synthesis and biological evaluation of BMS-986120 and its deuterated derivatives as PAR4 antagonists.
Topics: Animals; Benzofurans; Blood Platelets; Deuterium; Drug Stability; Humans; Imidazoles; Male; Mice, Inbred ICR; Microsomes, Liver; Morpholines; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thrombin; Thiazoles | 2019 |