deuterium has been researched along with serine in 71 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (38.03) | 18.7374 |
| 1990's | 12 (16.90) | 18.2507 |
| 2000's | 22 (30.99) | 29.6817 |
| 2010's | 8 (11.27) | 24.3611 |
| 2020's | 2 (2.82) | 2.80 |
| Authors | Studies |
|---|---|
| Dubrow, R; Pizer, LI | 1 |
| Winicov, I | 1 |
| Denu, JM; Fitzpatrick, PF | 2 |
| Abeles, RH; Krodel, E; Massey, V; Walsh, CT | 1 |
| Graham, JM; Wallach, DF | 1 |
| Ahrens, H; Korytnyk, W | 1 |
| Abeles, RH; Schonbrunn, A; Walsh, CT | 1 |
| Gaucher, GM; Roche, RS; Voordouw, G | 1 |
| McPhie, P; Miles, EW | 1 |
| Klein, MP; Llinás, M; Neilands, JB | 1 |
| Grenouillet, P; Martin, RP; Ptak, M; Rossi, A | 1 |
| Chen, MS; Schirch, LV | 1 |
| Robillard, G; Shulman, RG | 1 |
| Abernethy, D; Fitzgerald, TJ; Walaszek, EJ | 1 |
| Gibson, F; O'Brien, IG | 1 |
| Hubbard, CD; Kirsch, JF | 1 |
| Flavin, M; Posner, BI | 1 |
| Bender, ML; Polgár, L | 1 |
| Dugas, H; Kaplan, H; Symonds, VB; Whitaker, DR | 1 |
| Sheard, B; Shulman, RG; Yamane, T | 1 |
| Flavin, M; Guggenheim, S | 1 |
| Kaplan, H; Whitaker, DR | 1 |
| White, RH | 3 |
| Cleland, WW; Cook, PF; Grimshaw, CE | 1 |
| Belikov, VM; Dementieva, IS; Faleev, NG; Gogoleva, OI; Zakomirdina, LN | 1 |
| Cook, PF; Dunn, MF; Hwang, CC; Minter, DE; Woehl, EU | 1 |
| Dunn, MF; Hur, O; Leja, C | 1 |
| Connelly, GP; McIntosh, LP | 1 |
| Cook, PF; Kim, SK; Kredich, NM; Nalabolu, SR; Rege, VD; Schnackerz, KD; Tai, CH; Yoon, MY | 1 |
| Emmett, MR; Hendrickson, CL; Li, W; Marshall, AG; Wang, F; Wu, L; Zhang, YL; Zhang, ZY | 1 |
| Digits, JA; Hedstrom, L | 1 |
| Overman, SA; Thomas, GJ | 1 |
| Glavas, S; Tanner, ME | 1 |
| Ro, HS; Wilson Miles, E | 1 |
| Fan, YX; McPhie, P; Miles, EW | 1 |
| Ferry, JG; Tripp, BC | 1 |
| Crowder, MW; Taylor, RA; Yanchak, MP | 1 |
| Arabshahi, A; Berger, E; Frey, PA; Schilling, JF; Wei, Y | 1 |
| Dunn, MF; Ferrari, D; Miles, EW; Yang, LH | 1 |
| Epand, RF; Epand, RM; Martin, I; Ruysschaert, JM | 1 |
| Baggott, JE | 1 |
| Larsen, TM; Poyner, RR; Reed, GH; Wong, SW | 1 |
| Cook, PF; Daum, S; Tai, CH | 1 |
| Polgár, L; Sárkány, Z | 1 |
| GRUENEWALD, H; RACHEL, E; WHITE, AM | 1 |
| HENDERSON, LE; STEVENS, CO; TOLBERT, BM | 1 |
| Cooks, RG; Nanita, SC; Schlosser, G; Takats, Z; Vekey, K | 1 |
| Anderson, VE; Ruszczycky, MW | 1 |
| Bigelow, J; Kevala, JH; Kim, HY | 1 |
| Malthouse, JP; Níbeilliú, ME | 1 |
| Fagin, AE; Gronert, S; O'Hair, RA | 1 |
| Burlingame, AL; Chalkley, RJ; Hansen, KC; Hart, GW; Trinidad, JC; Vosseller, K; Wells, L | 1 |
| Coats, BS; Davis, SR; Gregory, JF; Quinlivan, EP; Scheer, JB; Stacpoole, PW | 1 |
| Lifshitz, C; Marshall, AG; Mazurek, U; McFarland, MA | 1 |
| Bauer, D; Bröer, S; Coenen, HH; Hamacher, K; Langen, KJ; Palm, C; Pauleit, D; Zilles, K | 1 |
| Cook, PF; Izumi, Y; Karsten, WE; Ohshiro, T | 1 |
| Carey, PR; Fausto, R; Jarmelo, S; Lapinski, L; Nowak, MJ | 1 |
| Dangott, LJ; Fitzpatrick, PF; Sura, GR; Wang, S | 1 |
| Hasegawa, H; Hashimoto, T; Ichida, K; Masuda, N; Shinohara, Y | 1 |
| Deska, J; Hähn, S; Kazmaier, U | 1 |
| Hufnagle, DC; Pacey, GE; Spendel, WU; Taulbee-Combs, AR | 1 |
| Bie, Z; Poopari, MR; Xu, Y; Yang, G; Zhu, P | 1 |
| Ensle, P; Krawczyk, B; Müller, WM; Süssmuth, RD | 1 |
| Jingu, S; Kinoshita, K; Yamaguchi, J | 1 |
| Clark, RB; Dietz, C; Nichols, FC; Smith, MB | 1 |
| Eckelmann, D; Kusari, S; Spiteller, M | 1 |
| Au, DF; Ostrovsky, D; Reed, SM; Rickertsen, DRL; Vugmeyster, L | 1 |
| Dan, G; Lin, K; Ma, L; Wang, Z; Zhang, R | 1 |
71 other study(ies) available for deuterium and serine
| Article | Year |
|---|---|
Transient kinetic and deuterium isotope effect studies on the catalytic mechanism of phosphoglycerate dehydrogenase.
Topics: Alcohol Oxidoreductases; Carbohydrate Dehydrogenases; Computers; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Serine; Spectrometry, Fluorescence; Time Factors | 1977 |
The mechanism of end product inhibition of serine biosynthesis. V. Mechanism of serim inhibition of phosphoglycerate dehydrogenases.
Topics: Alcohol Oxidoreductases; Deuterium; Escherichia coli; Glyceric Acids; Hydrogen-Ion Concentration; NAD; Organophosphorus Compounds; Protein Binding; Serine; Thermodynamics | 1975 |
pH and kinetic isotope effects on the reductive half-reaction of D-amino acid oxidase.
Topics: Alanine; D-Amino-Acid Oxidase; Deuterium; Glycine; Hydrogen-Ion Concentration; Isotope Labeling; Kinetics; Mathematics; Models, Theoretical; Serine | 1992 |
Studies on the elimination reaction of D-amino acid oxidase with -amino- -chlorobutyrate. Further evidence for abstraction of substrate -hydrogen as a proton.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Apoproteins; Catalysis; Chlorine; D-Amino-Acid Oxidase; Deuterium; Hydrogen; Isomerism; Keto Acids; Kidney; Kinetics; Osmolar Concentration; Oxidation-Reduction; Oxygen Consumption; Protons; Serine; Spectrophotometry; Swine; Temperature; Threonine; Tritium | 1973 |
Protein conformational transitions in the erythrocyte membrane.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Alcohols; Caseins; Cell Membrane; Deuterium; Edetic Acid; Enzyme Activation; Erythrocytes; Freeze Drying; Humans; Hydrolysis; Infrared Rays; Inosine Nucleotides; Lysine; Magnesium; Myoglobin; Peptides; Phenylalanine; Phosphorus Isotopes; Potassium; Protein Conformation; Protein Hydrolysates; Serine; Sodium; Spectrophotometry | 1971 |
5-homopyridoxals, 5-thiopyridoxal, and related compounds. Synthesis, tautomerism, and biological properties.
Topics: Adenocarcinoma; Animals; Deuterium; Female; Hydro-Lyases; Infrared Rays; Liver; Lymphoid Tissue; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Mice; Neutrophils; Phosphotransferases; Pyridoxine; Rats; Saccharomyces; Serine; Spectrum Analysis; Transferases; Tyrosine Transaminase | 1971 |
Studies on the mechanism of action of D-amino acid oxidase. Evidence for removal of substrate -hydrogen as a proton.
Topics: Alanine; Chemical Phenomena; Chemistry; Chlorine; D-Amino-Acid Oxidase; Deuterium; Flavin-Adenine Dinucleotide; Hydrogen; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Models, Chemical; Nitrogen; Oxygen; Phenylhydrazines; Proline; Protons; Pyruvates; Quaternary Ammonium Compounds; Serine; Spectrophotometry; Stereoisomerism; Thiosemicarbazones; Tritium; Ultraviolet Rays | 1971 |
Physiochemical properties of thermomycolase, the thermostable, extracellular, serine protease of the fungus Malbranchea pulchella.
Topics: Actinomyces; Binding Sites; Calcium; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Deuterium; Drug Stability; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Hot Temperature; Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Macromolecular Substances; Molecular Weight; Protein Binding; Protein Conformation; Protein Denaturation; Serine; Spectrophotometry, Ultraviolet; Time Factors; Ultracentrifugation; Viscosity | 1974 |
Evidence for a rate-determining proton abstraction in the serine deaminase reaction of the beta 2 subunit of tryptophan synthetase.
Topics: Deuterium; Escherichia coli; Kinetics; L-Serine Dehydratase; Macromolecular Substances; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mathematics; Models, Chemical; Protons; Pyridoxal Phosphate; Schiff Bases; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan Synthase | 1974 |
The solution conformation of the ferrichromes. V. The hydrogen exchange kinetics of ferrichrome analogues; the conformational state of the peptides.
Topics: Aluminum; Amides; Binding Sites; Chemical Phenomena; Chemistry; Deuterium; Gallium; Glycine; Half-Life; Hydrogen; Hydroxamic Acids; Iron Chelating Agents; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Peptides, Cyclic; Protons; Serine; Solubility; Thermodynamics | 1973 |
Interactions between copper (II) ions and L-threonine, L-allo-threonine and L-serine in aqueous solution.
Topics: Binding Sites; Circular Dichroism; Copper; Deuterium; Hydrogen-Ion Concentration; Isomerism; Ligands; Mathematics; Molecular Conformation; Optical Rotation; Protein Binding; Serine; Spectrophotometry; Threonine | 1973 |
Serine transhydroxymethylase. Studies on the role of tetrahydrofolate.
Topics: Animals; Binding Sites; Carbon Radioisotopes; Catalysis; Deuterium; Formaldehyde; Glycine; Hydrogen-Ion Concentration; Imines; Kinetics; Liver; Models, Chemical; Protons; Rabbits; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Transferases; Tritium | 1973 |
High resolution nuclear magnetic resonance studies of the active site of chymotrypsin. I. The hydrogen bonded protons of the "charge relay" system.
Topics: Aspartic Acid; Binding Sites; Chymotrypsin; Chymotrypsinogen; Deuterium; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Serine | 1974 |
NMR investigation of histamine-phospholipid interaction.
Topics: Binding Sites; Deuterium; Ethanolamines; Histamine; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Molecular Conformation; Phosphatidylcholines; Phosphatidylethanolamines; Serine; Structure-Activity Relationship; Time Factors; Ultrasonics | 1974 |
The structure of enterochelin and related 2,3-dihydroxy-N-benzoylserine conjugates from Escherichia coli.
Topics: Benzoates; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Deuterium; Electrophoresis; Enterobacter; Escherichia coli; Infrared Rays; Iron; Magnetic Resonance Spectroscopy; Models, Structural; Molecular Weight; Peptides; Serine; Spectrophotometry | 1970 |
Acylation of chymotrypsin by active esters of nonspecific substrates. Evidence for a transient acylimidazole intermediate.
Topics: Acylation; Benzoates; Catalysis; Chemical Phenomena; Chemistry; Chymotrypsin; Deuterium; Dinitrophenols; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Mathematics; Models, Chemical; Nitrophenols; Protein Binding; Serine; Structure-Activity Relationship | 1972 |
Cystathionine -synthase. Studies of hydrogen exchange reactions.
Topics: Alanine; Aminobutyrates; Catalysis; Chemical Phenomena; Chemistry; Cystathionine; Cysteine; Deuterium; Homoserine; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Salmonella; Serine; Succinates; Tritium | 1972 |
The nature of general base-general acid catalysis in serine proteases.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Deuterium; Endopeptidases; Histidine; Kinetics; Models, Chemical; Models, Structural; Serine | 1969 |
A comparison of properties of the alpha-lytic protease of Sorangium sp. and porcine elastase.
Topics: Alanine; Amino Acids; Animals; Deuterium; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Ketones; Kinetics; Leucine; Myxomycetes; Optical Rotatory Dispersion; Pancreatic Elastase; Peptide Hydrolases; Serine; Swine | 1970 |
Nuclear magnetic resonance study of cyanoferrimyoglobin; identification of pseudocontact shifts.
Topics: Alanine; Ammonia; Animals; Cetacea; Chemical Phenomena; Chemistry; Cyanides; Deuterium; Dolphins; Electrons; Histidine; Horses; Magnetic Resonance Spectroscopy; Methylation; Myoglobin; Protons; Serine; Temperature | 1970 |
Proton retention in the gamma-elimination reaction catalysed by cystathionine gamma-synthase.
Topics: Cysteine; Deuterium; Dinitrophenols; Hydrazines; Hydro-Lyases; Hydrogen; Keto Acids; Magnetic Resonance Spectroscopy; Protons; Pyridoxal Phosphate; Serine; Succinates; Tritium; Water | 1968 |
Kinetic properties of the alpha-lytic protease of Sorangium sp., a bacterial homologue of the pancreatopeptidases.
Topics: Acetates; Amino Acid Sequence; Arginine; Bacteria; Catalysis; Chymotrypsin; Deuterium; Electrophoresis; Esters; Histidine; Hydrogen-Ion Concentration; Kinetics; Nitrophenols; Pancreatic Elastase; Peptide Hydrolases; Protease Inhibitors; Protein Binding; Serine; Spectrophotometry; Trypsin; Tryptophan; Tyrosine | 1969 |
Proton exchange on carbons 2 and 3 of serine during their conversion into methyl groups of methionine and thymine in Escherichia coli.
Topics: Deuterium; Escherichia coli; Methionine; Mutation; Serine; Species Specificity; Thymine | 1983 |
An evaluation of the in vivo metabolism of cystine in Escherichia coli using stable isotopes.
Topics: Culture Media; Cystine; Deuterium; Escherichia coli; Methionine; Serine | 1983 |
Use of isotope effects and pH studies to determine the chemical mechanism of Bacillus subtilis L-alanine dehydrogenase.
Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Bacillus subtilis; Chemical Phenomena; Chemistry, Physical; Deuterium; Hydrogen-Ion Concentration; Mathematics; NAD; Serine | 1981 |
Metabolism of L-[sulfane-34S]thiocystine by Escherichia coli.
Topics: Cysteine; Cystine; Deuterium; Escherichia coli; Hydrogen Sulfide; Serine; Sulfur Isotopes | 1982 |
2-Methyl-L-tryptophan is a substrate of tryptophanase.
Topics: Absorption; Deuterium; Escherichia coli; Indoles; Ions; Kinetics; Pyruvates; Pyruvic Acid; Quaternary Ammonium Compounds; Serine; Substrate Specificity; Tryptophan; Tryptophanase | 1995 |
Intrinsic primary, secondary, and solvent kinetic isotope effects on the reductive half-reaction of D-amino acid oxidase: evidence against a concerted mechanism.
Topics: Alanine; Catalysis; D-Amino-Acid Oxidase; Deuterium; Glycine; Kinetics; Serine; Solvents; Structure-Activity Relationship; Tritium | 1994 |
Kinetic isotope effects as a probe of the beta-elimination reaction catalyzed by O-acetylserine sulfhydrylase.
Topics: Catalysis; Cysteine Synthase; Deuterium; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Molecular Probes; Salmonella typhimurium; Schiff Bases; Serine; Spectrophotometry; Tritium | 1996 |
Evidence of a low-barrier hydrogen bond in the tryptophan synthase catalytic mechanism.
Topics: Binding Sites; Catalysis; Deuterium; Hydrogen Bonding; Kinetics; Protein Conformation; Salmonella typhimurium; Schiff Bases; Serine; Spectrophotometry; Tryptophan Synthase | 1996 |
Characterization of a buried neutral histidine in Bacillus circulans xylanase: internal dynamics and interaction with a bound water molecule.
Topics: Bacillus; Deuterium; Histidine; Hydrogen; Hydrogen-Ion Concentration; Hydroxides; Kinetics; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Protein Binding; Serine; Tyrosine; Water; Xylan Endo-1,3-beta-Xylosidase; Xylosidases | 1998 |
Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate.
Topics: Alanine; Binding Sites; Circular Dichroism; Cysteine; Cysteine Synthase; Deuterium; Enzyme Activation; Enzyme Stability; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Insertional; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1998 |
Conformational and dynamic changes of Yersinia protein tyrosine phosphatase induced by ligand binding and active site mutation and revealed by H/D exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.
Topics: Amino Acid Sequence; Binding Sites; Cyclotrons; Cysteine; Deuterium; Endopeptidases; Hydrogen; Hydrolysis; Ligands; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; Protein Conformation; Protein Tyrosine Phosphatases; Serine; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Threonine; Yersinia | 1998 |
Kinetic mechanism of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase.
Topics: Amino Acid Substitution; Animals; Binding Sites; Cysteine; Deuterium; Humans; IMP Dehydrogenase; Kinetics; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Mycophenolic Acid; NAD; Protein Binding; Serine; Spectrometry, Fluorescence; Thermodynamics; Tritrichomonas foetus | 1999 |
Raman markers of nonaromatic side chains in an alpha-helix assembly: Ala, Asp, Glu, Gly, Ile, Leu, Lys, Ser, and Val residues of phage fd subunits.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Deuterium; DNA, Single-Stranded; Glutamic Acid; Glycine; Inovirus; Isoleucine; Lysine; Molecular Sequence Data; Protein Structure, Secondary; Serine; Spectrum Analysis, Raman; Valine; Viral Proteins; Virus Assembly | 1999 |
Catalytic acid/base residues of glutamate racemase.
Topics: Amino Acid Isomerases; Amino Acids; Catalysis; Cysteine; Deuterium; Glutamates; Hydrogen-Ion Concentration; Kinetics; Lactobacillus; Mutagenesis, Site-Directed; Serine; Stereoisomerism | 1999 |
Catalytic mechanism of the tryptophan synthase alpha(2)beta(2) complex. Effects of pH, isotopic substitution, and allosteric ligands.
Topics: Alanine; Allosteric Regulation; Catalytic Domain; Deuterium; Glycine; Hydrogen-Ion Concentration; Indoles; Ligands; Models, Chemical; Oxindoles; Pyridoxal Phosphate; Salmonella typhimurium; Serine; Tryptophan Synthase | 1999 |
Regulation of tryptophan synthase by temperature, monovalent cations, and an allosteric ligand. Evidence from Arrhenius plots, absorption spectra, and primary kinetic isotope effects.
Topics: Allosteric Regulation; Allosteric Site; Catalysis; Cations, Monovalent; Cesium; Chlorides; Deuterium; Enzyme Activation; Glycerophosphates; Guanidine; Kinetics; Ligands; Protein Conformation; Salmonella typhimurium; Serine; Sodium Chloride; Spectrum Analysis; Temperature; Thermodynamics; Tryptophan Synthase | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Mutational analysis of metallo-beta-lactamase CcrA from Bacteroides fragilis.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Bacterial Proteins; Bacteroides fragilis; beta-Lactamases; Cysteine; Deuterium; DNA Mutational Analysis; DNA, Bacterial; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Kinetics; Metalloproteins; Mutagenesis, Site-Directed; Protons; Recombinant Proteins; Serine; Solvents; Zinc | 2000 |
Acid-base catalysis by UDP-galactose 4-epimerase: correlations of kinetically measured acid dissociation constants with thermodynamic values for tyrosine 149.
Topics: Alanine; Catalysis; Deuterium; Electron Transport; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protons; Serine; Spectrometry, Fluorescence; Temperature; Thermodynamics; Tyrosine; UDPglucose 4-Epimerase | 2001 |
Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity.
Topics: Alanine; Allosteric Regulation; Aniline Compounds; Aspartic Acid; Benzimidazoles; beta-Alanine; Catalysis; Deuterium; Enzyme Activation; Hydroxylamines; Indoles; Kinetics; Multienzyme Complexes; Mutagenesis, Site-Directed; Pyruvic Acid; Salmonella typhimurium; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Titrimetry; Tryptophan Synthase | 2001 |
Membrane interactions of mutated forms of the influenza fusion peptide.
Topics: Alanine; Amino Acid Sequence; Deuterium; Glutamic Acid; Glycine; Hemagglutinin Glycoproteins, Influenza Virus; Kinetics; Lipid Bilayers; Membrane Fusion; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphorus Isotopes; Protein Conformation; Protein Structure, Secondary; Serine; Spectroscopy, Fourier Transform Infrared; Valine; Viral Fusion Proteins | 2001 |
Metabolism of methionine derived from deuterated serine infused in a human.
Topics: Amino Acids; Deuterium; Humans; Kinetics; Methionine; Methylation; Mitochondria; Serine | 2001 |
Functional and structural changes due to a serine to alanine mutation in the active-site flap of enolase.
Topics: Alanine; Amino Acid Substitution; Catalytic Domain; Crystallography, X-Ray; Deuterium; Enzyme Activation; Escherichia coli; Kinetics; Metals; Models, Molecular; Mutagenesis, Site-Directed; Phosphopyruvate Hydratase; Protein Conformation; Protein Folding; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Static Electricity; Thermodynamics | 2002 |
Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction.
Topics: Alanine; Aspartic Acid; Binding Sites; Catalysis; Circular Dichroism; Cysteine Synthase; Deuterium; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Pyridines; Pyridoxal Phosphate; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity | 2003 |
The unusual catalytic triad of poliovirus protease 3C.
Topics: 3C Viral Proteases; Catalysis; Catalytic Domain; Cysteine; Cysteine Endopeptidases; Deuterium; Glutamic Acid; Glutamine; Glycine; Hydrogen-Ion Concentration; Kinetics; Methionine; Models, Chemical; Mutagenesis, Site-Directed; Poliovirus; Serine; Solvents; Substrate Specificity; Temperature; Thermodynamics; Viral Proteins | 2003 |
THE BIOGENESIS OF CHOLINE AND METHIONINE METHYL GROUPS AND OF THE SERINE HYDROXYMETHYL GROUP FROM INTRAMOLECULARLY LABELED FORMALDEHYDE-14C,D2.
Topics: Carbon Isotopes; Choline; Chromatography; Creatine; Creatinine; Deuterium; Formaldehyde; Formates; Liver; Methionine; Proteins; Rats; Research; Serine; Urine | 1964 |
RADIATION CHEMISTRY OF PROTEINS. II. ENZYMIC ACTIVITY AND DEUTERIUM EXCHANGE PROPERTIES OF LYSOZYME AND ALPHA-CHYMOTRYPSIN.
Topics: Amino Acids; Cesium Isotopes; Chromatography; Chymotrypsin; Deuterium; Muramidase; Proteins; Radiation Effects; Research; Serine; Tryptophan | 1964 |
Atmospheric pressure gas-phase H/D exchange of serine octamers.
Topics: Atmospheric Pressure; Deuterium; Deuterium Exchange Measurement; Gases; Isomerism; Mass Spectrometry; Serine | 2003 |
Tartrate dehydrogenase reductive decarboxylation: stereochemical generation of diastereotopically deuterated hydroxymethylenes.
Topics: Alcohol Oxidoreductases; Catalysis; Decarboxylation; Deuterium; Enzyme Activation; Glyceric Acids; Hydrocarbons; Methane; Molecular Conformation; Oxidation-Reduction; Serine; Stereoisomerism; Tartrates | 2004 |
Substrate preference in phosphatidylserine biosynthesis for docosahexaenoic acid containing species.
Topics: Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Deuterium; Docosahexaenoic Acids; Lipid Bilayers; Microsomes; Microsomes, Liver; Phosphatidylcholines; Phosphatidylserines; Rats; Serine; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity | 2004 |
The stereospecificity and catalytic efficiency of the tryptophan synthase-catalysed exchange of the alpha-protons of amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Catalysis; Deuterium; Glycine Hydroxymethyltransferase; Hydrogen; Kinetics; Norleucine; Nuclear Magnetic Resonance, Biomolecular; Predictive Value of Tests; Protons; Serine; Stereoisomerism; Substrate Specificity; Tryptophan; Tryptophan Synthase; Valine | 2004 |
Ion/molecule reactions of the protonated serine octamer.
Topics: Amines; Deuterium; Deuterium Exchange Measurement; Diethylamines; Hydrogen; Ions; Kinetics; Ligands; Mass Spectrometry; Polymers; Protons; Serine | 2004 |
Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol.
Topics: Animals; Brain Chemistry; Cytosol; Deuterium; Dithiothreitol; Feasibility Studies; Glycosylation; Hydrolysis; Isotope Labeling; Mass Spectrometry; Mice; N-Acetylglucosaminyltransferases; Oxidation-Reduction; Peptide Mapping; Peptides; Phosphorylation; Protein Processing, Post-Translational; Proteins; Proteomics; Serine; Threonine | 2005 |
Dietary vitamin B-6 restriction does not alter rates of homocysteine remethylation or synthesis in healthy young women and men.
Topics: Adult; Carbon Isotopes; Deuterium; Female; Glycine; Homocysteine; Humans; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pyridoxal Phosphate; Serine; Vitamin B 6 | 2005 |
Isolation of isomers based on hydrogen/deuterium exchange in the gas phase.
Topics: Deuterium; Gases; Hydrogen; Isomerism; Serine; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared | 2004 |
Preferred stereoselective brain uptake of d-serine--a modulator of glutamatergic neurotransmission.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Chemistry; Deuterium; Glutamine; Male; Metabolic Clearance Rate; Neurotransmitter Agents; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Inbred F344; Serine; Stereoisomerism; Synaptic Transmission; Tissue Distribution | 2005 |
Reaction of serine-glyoxylate aminotransferase with the alternative substrate ketomalonate indicates rate-limiting protonation of a quinonoid intermediate.
Topics: Deuterium; Hyphomicrobium; Kinetics; Malonates; Quinones; Schiff Bases; Serine; Transaminases | 2005 |
Preferred conformers and photochemical (lambda > 200 nm) reactivity of serine and 3,3-dideutero-serine in the neutral form.
Topics: Algorithms; Decarboxylation; Deuterium; Hydrogen Bonding; Molecular Conformation; Photochemistry; Serine; Spectrum Analysis; Thermodynamics; Ultraviolet Rays | 2005 |
Identification by hydrogen/deuterium exchange of structural changes in tyrosine hydroxylase associated with regulation.
Topics: Animals; Catalytic Domain; Catecholamines; Cattle; Deuterium; Deuterium Exchange Measurement; Dopamine; Hydrogen; Peptide Fragments; Phosphorylation; Protein Binding; Rats; Serine; Tyrosine 3-Monooxygenase | 2009 |
Simultaneous determination of serine enantiomers in plasma using Mosher's reagent and stable isotope dilution gas chromatography-mass spectrometry.
Topics: Animals; Chromatography, Ion Exchange; Deuterium; Gas Chromatography-Mass Spectrometry; Isotope Labeling; Male; Phenylacetates; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Serine; Stereoisomerism | 2011 |
Stereoselective synthesis of deuterated β-cyclohexenylserine, a biosynthetic intermediate of the salinosporamides.
Topics: Cyclohexenes; Deuterium; Lactones; Molecular Structure; Pyrroles; Serine; Stereoisomerism | 2011 |
Collective mode frequency shifts in L-serine and a series of isotopologues in the terahertz regime.
Topics: Crystallization; Deuterium; Hydrogen Bonding; Molecular Weight; Serine; Temperature; Terahertz Spectroscopy | 2012 |
Conformations of serine in aqueous solutions as revealed by vibrational circular dichroism.
Topics: Circular Dichroism; Deuterium; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Conformation; Molecular Dynamics Simulation; Protons; Quantum Theory; Serine; Solutions; Solvents; Thermodynamics; Water | 2012 |
Deuterium labeled peptides give insights into the directionality of class III lantibiotic synthetase LabKC.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacteria; Bacteriocins; Deuterium; Enzyme Assays; Ligases; Molecular Sequence Data; Peptides; Serine | 2012 |
A surrogate analyte method to determine D-serine in mouse brain using liquid chromatography-tandem mass spectrometry.
Topics: Animals; Brain; Calibration; Chromatography, High Pressure Liquid; Deuterium; Mice; Nitrogen Radioisotopes; Quality Control; Serine; Stereoisomerism; Tandem Mass Spectrometry | 2013 |
Convergent synthesis of a deuterium-labeled serine dipeptide lipid for analysis of biological samples.
Topics: Chemistry Techniques, Synthetic; Deuterium; Dipeptides; Isotope Labeling; Lipid Metabolism; Lipids; Lipopeptides; Porphyromonas gingivalis; Serine; Stereoisomerism; Virulence Factors | 2017 |
Stable Isotope Labeling of Prodiginines and Serratamolides Produced by Serratia marcescens Directly on Agar and Simultaneous Visualization by Matrix-Assisted Laser Desorption/Ionization Imaging High-Resolution Mass Spectrometry.
Topics: Agar; Ammonium Chloride; Carbon Isotopes; Depsipeptides; Deuterium; Isotope Labeling; Methionine; Nitrogen Isotopes; Prodigiosin; Proline; Serine; Serratia marcescens; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2018 |
Dynamics of Serine-8 Side-Chain in Amyloid-β Fibrils and Fluorenylmethyloxycarbonyl Serine Amino Acid, Investigated by Solid-State Deuteron NMR.
Topics: Amino Acids; Amyloid; Deuterium; Nuclear Magnetic Resonance, Biomolecular; Serine | 2020 |
Coupling and decoupling CH stretching vibration of methylene and methine in serine conformers.
Topics: Deuterium; Serine; Spectrum Analysis, Raman; Vibration | 2023 |