Page last updated: 2024-08-22

deuterium and s-adenosylmethionine

deuterium has been researched along with s-adenosylmethionine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19904 (14.81)18.7374
1990's1 (3.70)18.2507
2000's15 (55.56)29.6817
2010's7 (25.93)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brivet, M; Roe, CR; Roe, DS; Sweetman, L1
Bali, D; Gregersen, N; Koeberl, DD; Liu, HM; Matern, D; Millington, DS; Stevens, RD; Young, SP1
Johnson, DW1
Bøersheim, E; Cree, MG; Sun, D; Wolfe, RR; Zhang, XJ1
Fok, TF; Ho, CS; Hui, J; Lam, CW; Law, LK; Ruiter, J; Tang, NL; Wanders, RJ1
Briand, G; Dessein, AF; Dobbelaere, D; Fontaine, M; Martin-Ponthieu, A; Mention-Mulliez, K; Vamecq, J1
Fong, BM; Leung, KS; Tam, S1
Gao, D; Jiang, Y; Li, S; Song, C; Tan, C1
Black, K; Gordon, EK; Kopin, IJ; Oliver, J1
Follmann, H; Gremels, G1
Ahn, HS; Mandel, LR; Vandenheuvel, WJ; Walker, RW1
Coward, JK; Crooks, PA; Floss, HG; Tsai, MD; Woodard, RW1
Frey, PA; Lieder, KW; Reed, GH; Wu, W1
Bandarian, V; Booker, S; Frey, PA; Lieder, KW; Reed, GH; Wu, W1
Bravo, JM; Härtner, T; Kannenberg, EL; Perzl, M; Rohmer, M1
Frey, PA; Magnusson, OT; Reed, GH1
Broderick, JB; Broderick, WE; Cheek, J; Hoffman, BM; Hong, W; Ortillo, D; Walsby, CJ1
Frey, PA; Magnusson, OT1
O'Hagan, D; Patterson, S1
Courtieu, J; Goss, RJ; Meddour, A; O'Hagan, D1
Al-Saad, K; Siems, WF; Wan, W; Zhao, G; Zhou, ZS1
Blom, HJ; den Heijer, M; Gellekink, H; Struys, EA; van Oppenraaij-Emmerzaal, D; van Rooij, A1
Eisenhofer, G; Menschikowski, M; Pacak, K; Peitzsch, M; Qin, N; Siegert, G1
Choi, SH; Liu, HW; Ruszczycky, MW1
Bandarian, V; Young, AP1
Koehler, P; Kopp, M; Morisset, R; Rychlik, M1
Bischoff, R; Kwiatkowski, M; van Pijkeren, A1

Reviews

1 review(s) available for deuterium and s-adenosylmethionine

ArticleYear
Mass spectrometric analysis of PTM dynamics using stable isotope labeled metabolic precursors in cell culture.
    The Analyst, 2019, Nov-18, Volume: 144, Issue:23

    Topics: Amino Acids; Animals; Carbon Isotopes; Cell Line, Tumor; Deuterium; Glucose; Humans; Isotope Labeling; Protein Processing, Post-Translational; Proteome; Proteomics; S-Adenosylmethionine

2019

Other Studies

26 other study(ies) available for deuterium and s-adenosylmethionine

ArticleYear
Evidence for a short-chain carnitine-acylcarnitine translocase in mitochondria specifically related to the metabolism of branched-chain amino acids.
    Molecular genetics and metabolism, 2000, Volume: 69, Issue:1

    Topics: Amino Acids, Branched-Chain; Biological Transport; Carnitine; Carnitine Acyltransferases; Cells, Cultured; Child; Deuterium; Fibroblasts; Humans; Intracellular Membranes; Isoleucine; Mass Spectrometry; Metabolism, Inborn Errors; Mitochondria; Oxidation-Reduction

2000
A comparison of in vitro acylcarnitine profiling methods for the diagnosis of classical and variant short chain acyl-CoA dehydrogenase deficiency.
    Clinica chimica acta; international journal of clinical chemistry, 2003, Volume: 337, Issue:1-2

    Topics: Acyl-CoA Dehydrogenase; Butyric Acid; Butyryl-CoA Dehydrogenase; Carbon Isotopes; Carnitine; Deuterium; DNA Mutational Analysis; Fibroblasts; Heterozygote; Homozygote; Humans; Malonates; Mutation, Missense; Palmitic Acid; Palmitoylcarnitine; Polymorphism, Genetic; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Spiro Compounds

2003
Synthesis of dicarboxylic acylcarnitines.
    Chemistry and physics of lipids, 2004, Volume: 129, Issue:2

    Topics: Carnitine; Deuterium; Dicarboxylic Acids; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization

2004
Measurement of stable isotopic enrichment and concentration of long-chain fatty acyl-carnitines in tissue by HPLC-MS.
    Journal of lipid research, 2006, Volume: 47, Issue:2

    Topics: Animals; Carbon Isotopes; Carnitine; Chromatography, High Pressure Liquid; Deuterium; Fluorocarbons; Male; Methods; Muscle, Skeletal; Palmitic Acid; Palmitoylcarnitine; Rabbits; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2006
A novel functional assay for simultaneous determination of total fatty acid beta-oxidation flux and acylcarnitine profiling in human skin fibroblasts using (2)H(31)-palmitate by isotope ratio mass spectrometry and electrospray tandem mass spectrometry.
    Clinica chimica acta; international journal of clinical chemistry, 2007, Volume: 382, Issue:1-2

    Topics: Carnitine; Cell Line; Deuterium; Fatty Acids; Fibroblasts; Humans; Lipid Metabolism, Inborn Errors; Mitochondria; Multienzyme Complexes; Oxidation-Reduction; Palmitates; Skin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2007
Deuterated palmitate-driven acylcarnitine formation by whole-blood samples for a rapid diagnostic exploration of mitochondrial fatty acid oxidation disorders.
    Clinica chimica acta; international journal of clinical chemistry, 2009, Volume: 406, Issue:1-2

    Topics: Acyl-CoA Dehydrogenases; Adult; Blood Specimen Collection; Carnitine; Case-Control Studies; Child; Child, Preschool; Deuterium; Fatty Acids; Female; Humans; Infant; Infant, Newborn; Kinetics; Male; Mitochondrial Diseases; Mutation; Oxidation-Reduction; Palmitates; Time Factors

2009
Quantification of acylglycines in human urine by HPLC electrospray ionization-tandem mass spectrometry and the establishment of pediatric reference interval in local Chinese.
    Talanta, 2012, Jan-15, Volume: 88

    Topics: 1-Butanol; Acylation; Adolescent; Asian People; Calibration; Carnitine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Deuterium; Female; Glycine; Humans; Infant; Infant, Newborn; Male; Metabolism, Inborn Errors; Reference Values; Sensitivity and Specificity; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2012
Isotope Labeling Strategies for Acylcarnitines Profile in Biological Samples by Liquid Chromatography-Mass Spectrometry.
    Analytical chemistry, 2019, 02-05, Volume: 91, Issue:3

    Topics: Biomarkers; Butylamines; Carnitine; Chromatography, Liquid; Deuterium; Humans; Isotope Labeling; Pyridinium Compounds; Tandem Mass Spectrometry

2019
Simultaneous assay by mass fragmentography of vanillyl mandelic acid, homovanillic acid, and 3-methoxy-4-hydroxy-phenethylene glycol in cerebrospinal fluid and urine.
    Biochemical medicine, 1974, Volume: 11, Issue:1

    Topics: Animals; Catechol O-Methyltransferase; Chromatography, Gas; Chromatography, Paper; Deuterium; Evaluation Studies as Topic; Glycols; Haplorhini; Homovanillic Acid; Humans; Infant, Newborn; Mass Spectrometry; Methods; Methoxyhydroxyphenylglycol; Microchemistry; Phenylacetates; S-Adenosylmethionine; Species Specificity; Vanilmandelic Acid

1974
Adenine nucleosides in solution: stabilisation of the anti-conformation by C-5' substituents.
    European journal of biochemistry, 1974, Aug-15, Volume: 47, Issue:1

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Aminohydrolases; Binding Sites; Circular Dichroism; Deuterium; Dimethyl Sulfoxide; Magnetic Resonance Spectroscopy; Molecular Conformation; Muscles; Optical Rotatory Dispersion; S-Adenosylmethionine; Solvents; Spectrophotometry, Ultraviolet

1974
Identification of N,N-dimethyltryptamine as the product of an in vitro enzymic methylation.
    Analytical biochemistry, 1972, Volume: 47, Issue:1

    Topics: Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Deuterium; Humans; Lung; Mass Spectrometry; Mathematics; Methods; Methylation; Methyltransferases; S-Adenosylmethionine; Tryptamines

1972
Stereochemical course of the transmethylation catalyzed by catechol O-methyltransferase.
    The Journal of biological chemistry, 1980, Oct-10, Volume: 255, Issue:19

    Topics: Carbon Radioisotopes; Catechol O-Methyltransferase; Deuterium; Methylation; Radioisotope Dilution Technique; S-Adenosylmethionine; Structure-Activity Relationship; Tritium

1980
Observation of a second substrate radical intermediate in the reaction of lysine 2,3-aminomutase: a radical centered on the beta-carbon of the alternative substrate, 4-thia-L-lysine.
    Biochemistry, 1995, Aug-22, Volume: 34, Issue:33

    Topics: Amino Acid Isomerases; Clostridium; Cysteine; Deuterium; Electrochemistry; Electron Spin Resonance Spectroscopy; Intramolecular Transferases; Kinetics; S-Adenosylmethionine; Substrate Specificity

1995
Lysine 2,3-aminomutase and trans-4,5-dehydrolysine: characterization of an allylic analogue of a substrate-based radical in the catalytic mechanism.
    Biochemistry, 2000, Aug-08, Volume: 39, Issue:31

    Topics: Binding Sites; Catalysis; Clostridium; Deuterium; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Enzyme Stability; Free Radicals; Hydrolysis; Intramolecular Transferases; Lysine; Molecular Conformation; S-Adenosylmethionine; Substrate Specificity

2000
Novel methylated triterpenoids of the gammacerane series from the nitrogen-fixing bacterium Bradyrhizobium japonicum USDA 110.
    European journal of biochemistry, 2001, Volume: 268, Issue:5

    Topics: Bradyrhizobium; Chromatography, Thin Layer; Cyclization; Deuterium; Gas Chromatography-Mass Spectrometry; Lyases; Magnetic Resonance Spectroscopy; Methionine; Methylation; Phylogeny; Polyisoprenyl Phosphates; Rhodopseudomonas; S-Adenosylmethionine; Symbiosis; Triterpenes

2001
Characterization of an allylic analogue of the 5'-deoxyadenosyl radical: an intermediate in the reaction of lysine 2,3-aminomutase.
    Biochemistry, 2001, Jul-03, Volume: 40, Issue:26

    Topics: Allyl Compounds; Carbon Isotopes; Clostridium; Coenzymes; Deoxyadenosines; Deuterium; Electron Spin Resonance Spectroscopy; Enzyme Activation; Enzyme Stability; Free Radicals; Intramolecular Transferases; Kinetics; Models, Chemical; S-Adenosylmethionine; Temperature

2001
Electron-nuclear double resonance spectroscopic evidence that S-adenosylmethionine binds in contact with the catalytically active [4Fe-4S](+) cluster of pyruvate formate-lyase activating enzyme.
    Journal of the American Chemical Society, 2002, Mar-27, Volume: 124, Issue:12

    Topics: Acetyltransferases; Carbon Isotopes; Catalysis; Deuterium; Electron Spin Resonance Spectroscopy; Enzymes; Iron-Sulfur Proteins; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; S-Adenosylmethionine

2002
Facile hydrogen-deuterium exchange at the 5'-position of an analogue of S-adenosyl-l-methionine.
    Bioorganic chemistry, 2002, Volume: 30, Issue:1

    Topics: Deuterium; Hydrogen; Kinetics; Molecular Conformation; Molecular Structure; S-Adenosylmethionine; Thermodynamics

2002
Biosynthetic studies on the tropane alkaloid hyoscyamine in Datura stramonium; hyoscyamine is stable to in vivo oxidation and is not derived from littorine via a vicinal interchange process.
    Phytochemistry, 2002, Volume: 61, Issue:3

    Topics: Atropine; Atropine Derivatives; Carbon Isotopes; Cell Extracts; Cells, Cultured; Cobamides; Datura stramonium; Deuterium; Gas Chromatography-Mass Spectrometry; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; Plant Roots; S-Adenosylmethionine

2002
Assay for the enantiomeric analysis of [2H1]-fluoroacetic acid: insight into the stereochemical course of fluorination during fluorometabolite biosynthesis in streptomyces cattleya.
    Journal of the American Chemical Society, 2003, Jan-15, Volume: 125, Issue:2

    Topics: Deuterium; Fluoroacetates; Glycerol; Nuclear Magnetic Resonance, Biomolecular; S-Adenosylmethionine; Stereoisomerism; Streptomyces; Succinic Acid; Threonine

2003
Rapid screening for S-adenosylmethionine-dependent methylation products by enzyme-transferred isotope patterns analysis.
    Rapid communications in mass spectrometry : RCM, 2004, Volume: 18, Issue:3

    Topics: Deuterium; Escherichia coli; Humans; Isotope Labeling; Methylation; Methyltransferases; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2004
Stable-isotope dilution liquid chromatography-electrospray injection tandem mass spectrometry method for fast, selective measurement of S-adenosylmethionine and S-adenosylhomocysteine in plasma.
    Clinical chemistry, 2005, Volume: 51, Issue:8

    Topics: Chromatography, Liquid; Deuterium; Humans; Radioisotope Dilution Technique; Reference Values; S-Adenosylhomocysteine; S-Adenosylmethionine; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2005
Double stable isotope ultra performance liquid chromatographic-tandem mass spectrometric quantification of tissue content and activity of phenylethanolamine N-methyltransferase, the crucial enzyme responsible for synthesis of epinephrine.
    Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:5

    Topics: Adrenal Gland Neoplasms; Animals; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Chromatography, High Pressure Liquid; Deuterium; Dexamethasone; Enzyme Assays; Epinephrine; Humans; Mice; Norepinephrine; Phenylethanolamine N-Methyltransferase; Pheochromocytoma; S-Adenosylmethionine; Sensitivity and Specificity; Tandem Mass Spectrometry

2013
EPR-kinetic isotope effect study of the mechanism of radical-mediated dehydrogenation of an alcohol by the radical SAM enzyme DesII.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Feb-05, Volume: 110, Issue:6

    Topics: Alcohols; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Kinetics; Oxidoreductases; S-Adenosylmethionine; Solvents; Streptomyces

2013
Mechanistic Studies of the Radical S-Adenosyl-L-methionine Enzyme 4-Demethylwyosine Synthase Reveal the Site of Hydrogen Atom Abstraction.
    Biochemistry, 2015, Jun-16, Volume: 54, Issue:23

    Topics: Archaeal Proteins; Biocatalysis; Carbon Radioisotopes; Carboxy-Lyases; Catalytic Domain; Deuterium; Free Radicals; Guanosine; Iron-Sulfur Proteins; Methanococcus; Methylation; Models, Molecular; Pyruvic Acid; RNA, Archaeal; RNA, Transfer, Phe; S-Adenosylmethionine; Stereoisomerism

2015
Stable Isotope Dilution Assays for Clinical Analyses of Folates and Other One-Carbon Metabolites: Application to Folate-Deficiency Studies.
    PloS one, 2016, Volume: 11, Issue:6

    Topics: Animals; Chickens; Deuterium; Folic Acid; Folic Acid Deficiency; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine

2016