deuterium has been researched along with piperidines in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (48.48) | 18.7374 |
| 1990's | 1 (3.03) | 18.2507 |
| 2000's | 5 (15.15) | 29.6817 |
| 2010's | 10 (30.30) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Baba, S; Horie, M; Shinozaki, K | 1 |
| Craig, JC; Culp, HW; Ekwuribe, N; McMahon, RE | 1 |
| Gelijkens, CF; Heykants, J; Knaeps, A; Lenoir, H; Van Peer, A; Woestenborghs, R | 1 |
| Gotto, AM; Kon, H | 1 |
| Babior, BM; Brown, DG; Law, PY; Lien, EL; Wood, JM | 1 |
| McConnell, HM; Morrisett, JD; Wien, RW | 1 |
| Baldassare, JJ; Breen, JJ; Ho, C; Lindstrom, TR | 1 |
| Andree, PJ; Zantema, A | 1 |
| Keefer, L; Lijinsky, W; Loo, J; Ross, AE | 1 |
| Böhme, H; Dehmel, H | 2 |
| Brown, DJ; Ford, PW | 1 |
| Caughey, WS; McLees, BD | 1 |
| Blake, MI; Fang, SM; Rhodes, HJ | 1 |
| Balgavý, P; Cizmárik, J; Gawrisch, K; Národa, J | 1 |
| Asada, Y; Misono, H; Sawada, S; Soda, K; Suzuki, T; Tanizawa, K | 1 |
| Ito, H; Kikuchi, K; Matsui, K; Namiki, M; Sakurai, H; Sano, Y; Taniguchi, S; Yoshimura, T | 1 |
| Bartoli, S; Roelens, S | 1 |
| Bormans, GM; Bronfman, F; de Groot, TJ; Gilissen, C; van Leuven, F; Verbruggen, AM | 1 |
| Fujita, M; Fujiwara, K; Hirayama, S; Kim, WH; Ohki, Y; Okuyama, T; Sakanishi, Y; Tatsumi, K; Yoshioka, Y | 1 |
| Agrawal, AK; Chen, Z; Chiu, SH; Franklin, RB; Leung, KH | 1 |
| Axelsson, J; Bengtsson, E; Bergström, M; Långström, B; Razifar, P; Schneider, H | 1 |
| Bonjoch, J; Diaba, F | 1 |
| Camarano, S; González, A; Rossini, C | 1 |
| Cannon, JS; Olson, AC; Overman, LE; Solomon, NS | 1 |
| Busacca, CA; Hrapchak, M; Latli, B; Lorenz, JC; Senanayake, C | 1 |
| Bastarrachea, RA; Comuzzie, AG; DiPatrizio, NV; Higgins, PB; Kamath, S; Parks, EJ; Piomelli, D; Vaidyanathan, V; Voruganti, VS | 1 |
| Haddad, N; Hrapchak, M; Latli, B; Senanayake, CH; Song, JJ; Tang, W; Wei, X | 1 |
| Parekh, JM; Sanyal, M; Shrivastav, PS; Yadav, M | 1 |
| Andersen, TL; Lindhardt, AT; Modvig, A; Skrydstrup, T; Taaning, RH | 1 |
| Bessaire, T; Delatour, T; Stadler, RH; Tarres, A | 1 |
| Borges, S; Dumpit, R; Hendershot, S; Hesk, D; Koharski, D; Lavey, C; McNamara, P; Voronin, K | 1 |
| Armbruster, MR; Bythell, BJ; Edwards, JL; Guan, S; Huang, T | 1 |
33 other study(ies) available for deuterium and piperidines
| Article | Year |
|---|---|
[Scrambling of deuterium in catalytic reduction and isotope effect on gas chromatography of deuterium labeled piperidine (author's transl)].
Topics: Chromatography, Gas; Deuterium; Gas Chromatography-Mass Spectrometry; Piperidines | 1979 |
Mechanism of the dealkylation of tertiary amines by hepatic oxygenases. Stable isotope studies with 1-benzyl-4-cyano-4-phenylpiperidine.
Topics: Amino Acid Oxidoreductases; Animals; Deuterium; In Vitro Techniques; Microsomes, Liver; Nitriles; Oxygen Isotopes; Piperidines; Rats | 1979 |
The use and limitations of deuterated lorcainide in metabolism and pharmacokinetic studies.
Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Deuterium; Dogs; Gas Chromatography-Mass Spectrometry; Piperidines | 1985 |
Observations on the conformation of human serum high-density lipoproteins using infrared spectroscopy, circular dichroism, and electron spin resonance.
Topics: Amides; Benzene; Chemical Phenomena; Chemistry; Circular Dichroism; Cyclic N-Oxides; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Infrared Rays; Lipoproteins; Piperidines; Spectrum Analysis; Temperature | 1970 |
Synthesis and catalytic activity of spin-labeled cobinamide coenzymes.
Topics: Acetaldehyde; Amino Alcohols; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Circular Dichroism; Coenzymes; Cyclic N-Oxides; Deoxyadenosines; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Methylation; Models, Structural; Photolysis; Piperidines; Quaternary Ammonium Compounds; Spectrophotometry; Ultraviolet Rays; Vitamin B 12 | 1971 |
Spin-label-induced nuclear relaxation. Distances between bound saccharides, histidine-15, and tryptophan-123 on lysozyme in solution.
Topics: Acetamides; Acetates; Binding Sites; Chemical Phenomena; Chemistry; Cyclic N-Oxides; Deuterium; Electron Spin Resonance Spectroscopy; Glucosamine; Histidine; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Models, Structural; Muramidase; Oligosaccharides; Piperidines; Protein Conformation; Tryptophan | 1972 |
Magnetic resonance studies of human hemoglobins and their implications to the structure-function relationships in human normal and abnormal hemoglobins.
Topics: Australia; Binding Sites; Carboxyhemoglobin; Chromatography, Gel; Deuterium; Electron Spin Resonance Spectroscopy; Hemoglobins; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Japan; Magnetic Resonance Spectroscopy; Maryland; Methemoglobin; Oxyhemoglobins; Phosphates; Phosphatidylinositols; Piperidines; Protein Binding; Protein Conformation; South Africa; Spin Labels; Structure-Activity Relationship | 1973 |
Magnetic resonance studies on glutamate dehydrogenase.
Topics: Adenosine Diphosphate; Binding Sites; Deuterium; Electron Spin Resonance Spectroscopy; Glutamate Dehydrogenase; Guanine Nucleotides; Iodoacetates; Ketoglutaric Acids; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; NAD; Oxidation-Reduction; Piperidines; Protein Binding; Protein Conformation; Spin Labels | 1974 |
Studies of alkylation of nucleic acids in rats by cyclic nitrosamines.
Topics: Alkylation; Animals; Chromatography, Ion Exchange; Cyclization; Deuterium; Diazomethane; DNA; Esophagus; Hydrolysis; Liver; Mass Spectrometry; Morpholines; Nitrosamines; Nucleic Acids; Piperazines; Piperidines; Pyrrolidines; Rats; RNA; Tritium | 1973 |
[Chlorination of N-acetyl-piperidine. 15. N-alpha halogen alkyl-carbonic acid amide].
Topics: Acetates; Aluminum; Chemical Phenomena; Chemistry; Chlorine; Chromates; Deuterium; Lithium; Oxidation-Reduction; Piperidines; Spectrum Analysis | 1971 |
[Chlorination of various N-acetyl-piperidines. 18. N-alpha-halogen-alkyl-carbonic acid amide].
Topics: Aluminum; Amines; Chemical Phenomena; Chemistry; Chlorine; Deuterium; Lithium; Oxidation-Reduction; Piperidines | 1971 |
Purine studies. VI. Formation, hydrolysis, and aminolysis of some purine sulphoxides and sulphones.
Topics: Benzoates; Chemical Phenomena; Chemistry; Deuterium; Magnetic Resonance Spectroscopy; Piperidines; Purines; Spectrophotometry; Sulfones; Sulfoxides | 1969 |
Substituted deuteroporphyrins. V. Structures, stabilities, and properties of nickel(II) complexes with axial ligands.
Topics: Chemical Phenomena; Chemistry, Physical; Deuterium; Magnetic Resonance Spectroscopy; Nickel; Piperidines; Porphyrins; Spectrophotometry; Temperature; Thermodynamics | 1968 |
Synthesis of 2,6-dioxo-3-phthalimidopiperidine-3,4,4,5,5-d, and 2,5-dioxo-3-phthalimidopyrrolidine-3,4,4-d, from L-deuterio-glutamic acid and L-deuterio-aspartic acid.
Topics: Aspartic Acid; Carbon; Chemistry, Pharmaceutical; Deuterium; Eukaryota; Glutamates; Hydrogen; Nitrogen; Piperidines; Thalidomide | 1965 |
Effect of the local anesthetic heptacaine hydrochloride on the structured water in model phosphatidylcholine membrane: 2D-NMR and 31P-NMR study.
Topics: Chemical Phenomena; Chemistry, Physical; Deuterium; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphorus Isotopes; Piperidines; Temperature; Water | 1983 |
Stereochemistry of meso-alpha,epsilon-diaminopimelate decarboxylase reaction: the first evidence for pyridoxal 5'-phosphate dependent decarboxylation with inversion of configuration.
Topics: Bacillus; Bacterial Proteins; Cadaverine; Carboxy-Lyases; Deuterium; Kinetics; Lysine; Piperidines; Pyridoxal Phosphate; Radioisotope Dilution Technique | 1981 |
Quantitative determination of E5880 in rat plasma by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Animals; Chromatography, High Pressure Liquid; Deuterium; Injections, Intravenous; Male; Mass Spectrometry; Molecular Structure; Piperidines; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity | 1999 |
Binding of acetylcholine and tetramethylammonium to a cyclophane receptor: anion's contribution to the cation-pi interaction.
Topics: Acetylcholine; Cations; Chloroform; Deuterium; Ethers, Cyclic; Ligands; Models, Molecular; Piperidines; Quaternary Ammonium Compounds; Solubility; Static Electricity; Thermodynamics | 2002 |
Evaluation of 18F-FA-4 and 11C-pipzA-4 as radioligands for the in vivo evaluation of the high-affinity choline uptake system.
Topics: Animals; Autoradiography; Biphenyl Compounds; Carbon Radioisotopes; Cerebellum; Corpus Callosum; Corpus Striatum; Deuterium; Fluorine Radioisotopes; Hemicholinium 3; Kidney; Liver; Lung; Male; Membrane Transport Proteins; Mice; Myocardium; Piperidines; Radioligand Assay; Radiopharmaceuticals; Telencephalon; Tissue Distribution | 2003 |
Elimination-addition mechanism for nucleophilic substitution reaction of cyclohexenyl iodonium salts and regioselectivity of nucleophilic addition to the cyclohexyne intermediate.
Topics: Acetates; Alkenes; Alkynes; Cyclohexanes; Deuterium; Kinetics; Molecular Structure; Onium Compounds; Oxidation-Reduction; Piperidines; Stereoisomerism | 2004 |
In vitro and in vivo trans-esterification of 1-[2(R)-(2-amino-2-methylpropionylamino)-3-(1H-indol-3-yl)propionyl]-3(S)-benzyl-piperidine-3-carboxylic acid ethyl ester and the effects of ethanol on its pharmacokinetics in rats.
Topics: Administration, Oral; Animals; Area Under Curve; Carboxylic Acids; Carboxylic Ester Hydrolases; Chromatography, Liquid; Deuterium; Drug Evaluation, Preclinical; Drug Interactions; Esterification; Esters; Ethanol; Human Growth Hormone; Hydrolysis; Injections, Intravenous; Male; Mass Spectrometry; Metabolic Clearance Rate; Microsomes, Liver; Nitrophenols; Piperidines; Rats; Rats, Sprague-Dawley | 2004 |
A new application of pre-normalized principal component analysis for improvement of image quality and clinical diagnosis in human brain PET studies--clinical brain studies using [11C]-GR205171, [11C]-L-deuterium-deprenyl, [11C]-5-Hydroxy-L-Tryptophan, [11
Topics: Antiemetics; Brain; Brain Mapping; Carbon Radioisotopes; Deuterium; Humans; Image Processing, Computer-Assisted; Levodopa; Piperidines; Positron-Emission Tomography; Selegiline; Tetrazoles | 2006 |
NMR evidence of the kinetic and thermodynamic products in the NIS promoted cyclization of 1-phenyl-4-pentenylamines. Synthesis and reactivity of trans-2-phenyl-5-iodopiperidines.
Topics: Alkenes; Amines; Cyclization; Deuterium; Kinetics; Magnetic Resonance Spectroscopy; Piperidines; Thermodynamics | 2011 |
Origin of Epilachnapaenulata defensive alkaloids: incorporation of [1-13C]-sodium acetate and [methyl-2H3]-stearic acid.
Topics: Alkaloids; Amino Acids; Animals; Carbon Isotopes; Coleoptera; Deuterium; Piperidines; Sodium Acetate; Stearic Acids | 2012 |
Palladium(II)-catalyzed enantioselective synthesis of 2-vinyl oxygen heterocycles.
Topics: Acetamides; Benzoxazines; Catalysis; Chloroacetates; Chromans; Computer Simulation; Cyclization; Deuterium; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Oxygen; Palladium; Piperidines; Staining and Labeling; Stereoisomerism; Trichloroacetic Acid; Vinyl Compounds | 2012 |
Synthesis of a potent cathepsin s inhibitor labeled with deuterium and carbon-14.
Topics: Carbon Radioisotopes; Cathepsins; Deuterium; Morpholines; Piperidines | 2012 |
Selective cannabinoid-1 receptor blockade benefits fatty acid and triglyceride metabolism significantly in weight-stable nonhuman primates.
Topics: Acetic Acid; Animals; Biotransformation; Body Composition; Carbon Isotopes; Deuterium; Fatty Acids; Insulin Resistance; Kinetics; Lipolysis; Liver; Male; Palmitic Acid; Papio; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Subcutaneous Fat, Abdominal; Triglycerides; Waist Circumference | 2012 |
Sodium-proton exchanger isoform-1: synthesis of a potent inhibitor labeled with deuterium and carbon-14.
Topics: Benzamides; Carbon Radioisotopes; Deuterium; Guanidines; Piperidines; Protein Isoforms; Sodium-Hydrogen Exchangers | 2013 |
Stable-isotope dilution LC-MS/MS assay for determination of iloperidone and its two major metabolites, P 88 and P 95, in human plasma: application to a bioequivalence study.
Topics: Antipsychotic Agents; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Deuterium; Half-Life; Humans; Isotope Labeling; Isoxazoles; Piperidines; Solid Phase Extraction; Tandem Mass Spectrometry; Therapeutic Equivalency | 2013 |
Two-chamber hydrogen generation and application: access to pressurized deuterium gas.
Topics: Alkenes; Alkynes; Catalysis; Deuterium; Dioxanes; Dioxoles; Hydrogen; Isotope Labeling; Kinetics; Metals; Oxidation-Reduction; Phthalazines; Piperazines; Piperidines; Quinolines | 2014 |
Role of choline and glycine betaine in the formation of N,N-dimethylpiperidinium (mepiquat) under Maillard reaction conditions.
Topics: Alkaloids; Betaine; Carbon Radioisotopes; Choline; Chromatography, High Pressure Liquid; Deuterium; Hot Temperature; Kinetics; Lysine; Maillard Reaction; Methylation; Models, Chemical; Molecular Structure; Molecular Weight; Piperidines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
Synthesis of 3H, 13C,2H3,15N and 14C-labelled SCH 466036, a histamine 3 receptor antagonist.
Topics: Aminopyridines; Carbon Radioisotopes; Deuterium; Histamine H3 Antagonists; Nitrogen Isotopes; Piperidines; Radiopharmaceuticals; Tritium | 2015 |
Isomeric Differentiation and Acidic Metabolite Identification by Piperidine-Based Tagging, LC-MS/MS, and Understanding of the Dissociation Chemistries.
Topics: Chromatography, High Pressure Liquid; Citric Acid; Deuterium; Isocitrates; Isomerism; Piperidines; Tandem Mass Spectrometry | 2020 |