deuterium has been researched along with phenacetin in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baty, JD; Robinson, PR | 2 |
| Garland, WA; Nelson, SD; Sasame, HA | 1 |
| Baty, JD; Fox, WR; Lindsay, RM; Willis, RG | 1 |
| Chan, KK; Horning, MG; Pang, KS; Waller, L | 1 |
| Caddick, S; Farrant, RD; Lindon, JC; Nicholls, AW; Nicholson, JK; Wilson, ID | 1 |
| Guengerich, FP; Miller, GP; Yun, CH | 2 |
8 other study(ies) available for deuterium and phenacetin
| Article | Year |
|---|---|
Acetaminophen production in man after coadministration of acetanilid and phenacetin. A study with stable isotopes.
Topics: Acetaminophen; Acetanilides; Chromatography, Gas; Deuterium; Drug Combinations; Humans; Hydroxylation; Male; Mass Spectrometry; Phenacetin; Time Factors | 1977 |
Production in vitro of paracetamol from phenacetin and [2H]acetanilide: a study with stable isotopes [proceedings].
Topics: Acetaminophen; Acetanilides; Animals; Deuterium; Isotope Labeling; Liver; Male; Phenacetin; Phenobarbital; Rats | 1977 |
Primary and beta-secondary deuterium isotope effects in the O-deethylation of phenacetin.
Topics: Animals; Dealkylation; Deuterium; Gas Chromatography-Mass Spectrometry; Isotope Labeling; Kinetics; Microsomes, Liver; Phenacetin; Rabbits; Structure-Activity Relationship | 1976 |
In vitro studies on the deacetylation-reacetylation of arylamides and the transacetylation of arylamines by human and rat whole blood.
Topics: Acetanilides; Acetylation; Aniline Compounds; Animals; Arylamine N-Acetyltransferase; Blood Glucose; Chromatography, High Pressure Liquid; Deuterium; Diabetes Mellitus; Diabetes Mellitus, Experimental; Gas Chromatography-Mass Spectrometry; Glucose; Humans; Male; Phenacetin; Rats; Rats, Inbred Strains | 1991 |
Metabolite kinetics: formation of acetaminophen from deuterated and nondeuterated phenacetin and acetanilide on acetaminophen sulfation kinetics in the perfused rat liver preparation.
Topics: Acetaminophen; Acetanilides; Animals; Biotransformation; Deuterium; In Vitro Techniques; Kinetics; Liver; Male; Phenacetin; Rats; Rats, Inbred Strains; Sulfates | 1982 |
NMR spectroscopic studies on the metabolism and futile deacetylation of phenacetin in the rat.
Topics: Acetaminophen; Acetylation; Animals; Deuterium; Magnetic Resonance Spectroscopy; Male; Phenacetin; Rats; Rats, Sprague-Dawley | 1997 |
Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants.
Topics: Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Deuterium; Enzyme Activation; Ferric Compounds; Humans; Hydrogen Peroxide; Kinetics; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Phenacetin; Recombinant Proteins; tert-Butylhydroperoxide | 2000 |
Oxidations of p-alkoxyacylanilides catalyzed by human cytochrome P450 1A2: structure-activity relationships and simulation of rate constants of individual steps in catalysis.
Topics: Alanine; Alkylation; Amino Acid Substitution; Aspartic Acid; Catalysis; Cytochrome P-450 CYP1A2; Deuterium; Enzyme Activation; Humans; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenacetin; Protein Binding; Structure-Activity Relationship; Substrate Specificity | 2001 |