Compounds > deuterium
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deuterium and penicillanic acid

deuterium has been researched along with penicillanic acid in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Christensen, H; Martin, MT; Waley, SG1
Claes, PJ; De Meester, F; Piette, JL; Roets, E; Thomis, J; Vanderhaeghe, H1
Brenner, DG; Knowles, JR1
Makinen, MW; Mustafi, D; Sosa-Peinado, A1
Alkema, WB; de Vries, E; Floris, R; Janssen, DB1

Other Studies

5 other study(ies) available for deuterium and penicillanic acid

ArticleYear
Beta-lactamases as fully efficient enzymes. Determination of all the rate constants in the acyl-enzyme mechanism.
    The Biochemical journal, 1990, Mar-15, Volume: 266, Issue:3

    Topics: Acylation; Bacillus cereus; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Chemical Phenomena; Chemistry; Deuterium; Escherichia coli; Hydrolysis; Kinetics; Penicillanic Acid; Penicillin G; Staphylococcus aureus; Substrate Specificity

1990
Synthesis of deuterium- and tritium-labeled 6 beta-bromopenicillanic acid.
    The Journal of antibiotics, 1985, Volume: 38, Issue:1

    Topics: Chemical Phenomena; Chemistry; Deuterium; Isomerism; Penicillanic Acid; Tritium

1985
Penicillanic acid sulfone: an unexpected isotope effect in the interaction of 6 alpha- and 6 beta-monodeuterio and of 6,6-dideuterio derivatives with RTEM beta-lactamase from Escherichia coli.
    Biochemistry, 1981, Jun-23, Volume: 20, Issue:13

    Topics: beta-Lactamase Inhibitors; Deuterium; Escherichia coli; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Penicillanic Acid; Stereoisomerism; Sulbactam

1981
ENDOR structural characterization of a catalytically competent acylenzyme reaction intermediate of wild-type TEM-1 beta-lactamase confirms glutamate-166 as the base catalyst.
    Biochemistry, 2001, Feb-27, Volume: 40, Issue:8

    Topics: Acylation; Asparagine; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Catalysis; Deuterium; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Escherichia coli; Freezing; Glutamic Acid; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Penicillanic Acid; Penicillin G; Solvents; Spin Labels; Water

2001
Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of beta-lactam antibiotics.
    European journal of biochemistry, 2003, Volume: 270, Issue:18

    Topics: Acylation; Anti-Bacterial Agents; Binding Sites; Binding, Competitive; Catalysis; Cephalosporins; Deuterium; Escherichia coli; Glycine; Hydrolysis; Kinetics; Penicillanic Acid; Penicillin Amidase; Phenylacetates; Protons; Spectrophotometry, Ultraviolet; Substrate Specificity

2003