deuterium has been researched along with npi 2358 in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, H; Ding, Z; Guan, H; Hou, Y; Li, W; Wang, S; Zhao, J | 1 |
| Ding, Z; Guan, H; Hou, Y; Li, W; Ma, M; Sun, T; Wang, S | 1 |
| Cheng, H; Deng, M; Ding, Z; Dou, G; Hou, Y; Li, F; Li, W; Ma, M; Zhao, J | 1 |
| Ding, Z; Li, W; Li, Z; Ma, L; Ma, M; Wang, S; Wang, Y; Yang, J; Zhong, L | 1 |
4 other study(ies) available for deuterium and npi 2358
| Article | Year |
|---|---|
Development of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Cell Line; Deuterium; Diketopiperazines; Humans; Mice; Models, Molecular; Rats; Xenograft Model Antitumor Assays | 2017 |
Synthesis of deuterium-enriched and fluorine-substituted plinabulin derivatives and evaluation of their antitumor activities.
Topics: Antineoplastic Agents; Carbon-13 Magnetic Resonance Spectroscopy; Cell Proliferation; Cell Survival; Deuterium; Diketopiperazines; Fluorine; Humans; Jurkat Cells; Mass Spectrometry; Molecular Structure; Proton Magnetic Resonance Spectroscopy | 2017 |
In vitro and in vivo pharmacokinetic and pharmacodynamic study of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent.
Topics: Animals; Antineoplastic Agents; Blood Proteins; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Deuterium; Diketopiperazines; Female; Half-Life; Humans; Inhibitory Concentration 50; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Neoplasms; Protein Binding; Rats; Rats, Wistar; Tissue Distribution | 2018 |
Polymorphs, co-crystal structure and pharmacodynamics study of MBRI-001, a deuterium-substituted plinabulin derivative as a tubulin polymerization inhibitor.
Topics: Animals; Binding Sites; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Deuterium; Diketopiperazines; Humans; Mice; Mice, Nude; Molecular Conformation; Molecular Dynamics Simulation; Neoplasms; Protein Structure, Tertiary; Tubulin; Tubulin Modulators | 2019 |