Page last updated: 2024-08-22

deuterium and lysine

deuterium has been researched along with lysine in 104 studies

Research

Studies (104)

TimeframeStudies, this research(%)All Research%
pre-199041 (39.42)18.7374
1990's20 (19.23)18.2507
2000's28 (26.92)29.6817
2010's13 (12.50)24.3611
2020's2 (1.92)2.80

Authors

AuthorsStudies
Hvidt, A; Junager, F; Sorup, P1
Peticolas, WL1
Gonzalez, M; Martinez-Carrion, M; Slebe, JC1
Dvoráková, M; Kotyk, A1
Anders, MW; Fitzsimmons, ME; Harris, JW1
Gat, Y; Grossjean, M; Lewis, A; Pinevsky, I; Rothman, Z; Sheves, M; Sigrist, H; Takei, H1
Gerlt, JA; Kallarakal, AT; Kenyon, GL; Kozarich, JW; Landro, JA; Neidhart, DJ; Ransom, SC1
Amann, JM; Cook, GL; Hachey, DL; Klein, PD; Patterson, BW1
Lin, BH; Mangel, WF; Ramakrishnan, V1
Cohn, JS; Hachey, DL; Lichtenstein, AH; Millar, JS; Ordovas, JM; Schaefer, EJ1
Bloom, M; Devaux, PF; Hodges, RS; Neumann, JM; Roux, M1
Kelland, JG; Palcic, MM; Pickard, MA; Vederas, JC1
Graham, JM; Wallach, DF1
Kakimoto, Y; Kaneko, T; Mizote, H; Nakajima, T; Shiba, T1
Deslauriers, R; Garrigou-Lagrange, C; McGregor, H; Saitô, H; Sarantakis, D; Smith, IC; Walter, R1
Saito, H; Smith, IC2
Deslauriers, R; Smith, IC; Walter, R1
Glickson, JD; Havran, RT; Meienhofer, J; Schwartz, IL; Urry, DW; Walter, R1
Glickson, JD; Havran, RT; Urry, DW; Walter, R1
Bovey, FA; Brewster, AI; Dadok, J; Du Vigneaud, V; Ferger, MF; Scheraga, HA; Von Dreele, PH1
Glickson, JD; Urry, DW; Walter, R1
Deslauriers, R; Prasad, KU; Smith, IC; Walter, R1
Bradbury, EM; Cary, PD; Crane-Robinson, C; Rattle, HW1
Bukald, NE; Hirshfield, IN1
Christensen, HN; Quay, S1
Asquith, RS; Carthew, P1
Susi, H1
Kortt, AA; Liu, TY1
Balaram, P; Bothner-By, AA; Breslow, E1
Johnson, DF; Katz, R; Yeh, HJ1
Dimicoli, JL; Hélène, C2
Nakada, D; Young, RM1
Abbott, EH; Martell, AE1
Evans, MT; Irons, L; Petty, JH1
Brewster, AI; Du Vigneaud, V; Ferger, MF; Scheraga, HA; Von Dreele, PH1
Bovey, FA; Brewster, AI; Du Vigneaud, V; Ferger, MF; Scheraga, HA; Von Dreele, PH1
Barker, HA; Chirpich, TP; Costilow, RN; Zappia, V1
Banks, TE; Shafer, JA1
Lewin, S; Rosmarin, MN1
Antoni, F; Holland, J1
Lees, CW; von Hippel, PH1
Appel, P; Yang, JT1
Davidson, B; Fasman, GD1
Abe, M; Nakanishi, M; Nosoh, Y; Tsuboi, M1
Szawelski, RJ; Wharton, CW1
Asada, Y; Misono, H; Sawada, S; Soda, K; Suzuki, T; Tanizawa, K1
Ballinger, MD; Frey, PA; LoBrutto, R; Reed, GH1
Gloss, LM; Kirsch, JF1
Johnson, RS; Ohguro, H; Palczewski, K; Walsh, KA1
Burrin, DG; Frazer, M; Jahoor, F; Reeds, PJ1
Bier, DM; Hoerr, RA; Matthews, DE; Young, VR1
Ball, RO; Pencharz, PB; Zello, GA1
Minch, MJ; Vu, HM1
Akasako-Furukawa, A; Kanaya, S; Yamasaki, K1
Backwell, FR; Bequette, BJ; Buchan, V; Calder, AG; Crompton, LA; France, J; Kyle, CE; MaCrae, JC1
Overman, SA; Thomas, GJ1
Doyle, D; Ferrando, AA; Phillips, SM; Tipton, KD; Wolfe, RR1
Chooback, L; Cook, PF; Zhang, L1
Moynihan, DP; Parikh, S; Tonge, PJ; Xiao, G1
Ferry, JG; Tripp, BC1
Bandarian, V; Booker, S; Frey, PA; Lieder, KW; Reed, GH; Wu, W1
Blanchard, JS; Zheng, R1
Bagwell, C; Banik, U; Dunn, MF; Hur, O; Miles, EW; Weber-Ban, E; Yang, LH1
Forest, E; Gonzalez de Peredo, A; Latour, JM; Michaud-Soret, I; Saint-Pierre, C1
Bowler, BE; Kise, KJ1
Bequette, BJ; Hanigan, MD; Kyle, CE; Mabjeesh, SJ; MacRae, JC1
Bene, J; Bieber, LL; Bootsma, A; Cuebas, D; Gage, DA; Melegh, B; van Gennip, AH; Vaz, FM; Vreken, P; Wanders, RJ1
Costello, PJ; Henschke, PA1
Bradbury, EM; Chen, X; Gu, S; Pan, S1
Englander, SW; Lim, WK; Maity, H; Rumbley, JN1
Bolbach, G; Jensen, TR; Kjaer, K; Lahav, M; Leiserowitz, L; Shavit, E; Tang, M; Weissbuch, I; Zepik, H1
Adediran, SA; Cabaret, D; Pratt, RF; Wakselman, M1
Kavanagh, KL; Klimacek, M; Nidetzky, B; Wilson, DK1
Farrés, J; Fita, I; Ochoa, WF; Parés, X; Rosell, A; Valencia, E1
Arora, JS; Blair, IA; Lee, SH; Oe, T1
Ballou, DP; Marsh, EN; Xia, L1
Smith, CM1
Bindila, L; Cepo, T; Cindrić, M; Skrlin, A; Vuletić, M1
Leblanc, G; Lemonnier, R; León, X; Padrós, E1
Bindila, L; Cepo, T; Cindrić, M; Peter-Katalinić, J1
Byrd, JC; Freitas, MA; Knapp, AR; Lucas, DM; Parthun, MR; Ren, C; Su, X1
Arnett, SO; Gerratana, B; Townsend, CA1
Daily, AE; Greathouse, DV; Koeppe, RE; van der Wel, PC1
Bolon, D; Deshaies, RJ; Fushman, D; Haririnia, A; Purohit, N; Twarog, MZ; Verma, R1
Hansen, PE; Tomlinson, JH; Ullah, S; Williamson, MP1
Cook, PF; Lin, Y; West, AH1
Breen, NF; Castner, DG; Drobny, GP; Li, K; Weidner, T1
Giaccia, AJ; Hurski, AL; Okkelman, IA; Pestov, NB; Shchepinov, MS; Shmanai, VV1
Loh, CT; Otting, G; Qi, R; Su, XC1
Hansen, PE; Ishimoto, T; Ullah, S; Williamson, MP1
Andi, B; Bobyk, KD; Cook, PF; Kumar, VP; Thomas, LM; West, AH1
Chung, HW; Tu, SC1
Charrier, A; Merlier, F; Perrin, Y; Rippa, S; Zhao, Y1
Brown, JW; Hodge, K; Lamond, AI; Lewandowska, D; ten Have, S; Tillemans, V1
Ford, J; Fowler, K; Hansen, PE; Hebditch, M; Hounslow, AM; Williamson, MP1
Bessaire, T; Delatour, T; Stadler, RH; Tarres, A1
Brenna, JT; Fedarkevich, AM; Hurski, AL; Korneenko, TV; Pestov, NB; Shchepinov, MS; Shmanai, VV1
Di, Y; Lu, H; Tao, T; Zhang, L; Zhang, Y1
Danmaliki, GI; Hwang, PM; Liu, PB1
Ilyash, MY; Lahderanta, E; Markelov, DA; Mikhailova, ME; Neelov, IM; Sheveleva, NN; Tarasenko, II; Vovk, MA1
Allen, LH; Devi, S; Dharmar, M; Holt, RR; Keen, CL; Kurpad, AV; Preston, T; Sheshshayee, MS; Varkey, A1
Adhikari, J; Bergeron, L; Dauzhenka, T; Dickson, A; Dixon, T; Evdokimov, A; Gao, N; Imbriglio, J; Izaguirre, JA; Jain, S; Kolossváry, I; Li, Y; Lotz, S; MacPherson, D; McDargh, ZA; McGee, D; Mostofian, B; Pal, R; Pei, F; Razavi, AM; Ribeiro, JV; Ruprecht, B; Sachdeva, V; Shechter, S; Sherman, W; Shrestha, UR; Sparks, S; Vinitsky, A; Wiewiora, R; Wilkerson, T; Xu, H; Zhang, X; Zhou, W1

Trials

2 trial(s) available for deuterium and lysine

ArticleYear
Postexercise net protein synthesis in human muscle from orally administered amino acids.
    The American journal of physiology, 1999, Volume: 276, Issue:4

    Topics: Administration, Oral; Adult; Amino Acids; Amino Acids, Essential; Deuterium; Female; Humans; Leucine; Lysine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Physical Exertion

1999
Amino Acid Digestibility of Extruded Chickpea and Yellow Pea Protein is High and Comparable in Moderately Stunted South Indian Children with Use of a Dual Stable Isotope Tracer Method.
    The Journal of nutrition, 2020, 05-01, Volume: 150, Issue:5

    Topics: Amino Acids; Carbon Isotopes; Child; Cicer; Deuterium; Digestion; Female; Food Handling; Growth Disorders; Humans; India; Lysine; Male; Pisum sativum; Plant Proteins; Proline; Trypsin Inhibitors

2020

Other Studies

102 other study(ies) available for deuterium and lysine

ArticleYear
Physicochemical studies of a branched polypeptide antigen: poly(L-Tyr,L-Glu)-poly(DL-Ala)--poly(L-Lys).
    Biochimica et biophysica acta, 1977, Sep-27, Volume: 494, Issue:1

    Topics: Alanine; Antigens; Deuterium; Epitopes; Glutamates; Hydrogen; Hydrogen-Ion Concentration; Isoelectric Point; Lysine; Peptides; Protein Conformation; Spectrophotometry, Infrared; Structure-Activity Relationship; Tyrosine; Viscosity

1977
Application of Raman spectroscopy to biological macromolecules.
    Biochimie, 1975, Volume: 57, Issue:4

    Topics: Animals; Deuterium; DNA; Hydrogen-Ion Concentration; Lysine; Nucleic Acid Conformation; Nucleic Acid Denaturation; Peptides; Poly A-U; Poly I-C; Poly U; Protein Conformation; RNA, Transfer; Scattering, Radiation; Spectrum Analysis; Structure-Activity Relationship; Temperature; Vibration; Water

1975
Stereochemistry of holoaspartate transaminase after modification of the active site Lys-258.
    The Journal of biological chemistry, 1979, May-10, Volume: 254, Issue:9

    Topics: Animals; Aspartate Aminotransferases; Binding Sites; Deuterium; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Myocardium; Protein Conformation; Pyridoxamine; Swine

1979
Are proton symports in yeast directly linked to H(+)-ATPase acidification?
    Biochimica et biophysica acta, 1992, Mar-02, Volume: 1104, Issue:2

    Topics: Deuterium; Diethylstilbestrol; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Leucine; Lysine; Membrane Potentials; Proton-Translocating ATPases; Protons; Saccharomyces cerevisiae; Suloctidil

1992
Synthesis of [2-3H-ethyl]S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine and its use in covalent-binding studies.
    Analytical biochemistry, 1992, Aug-01, Volume: 204, Issue:2

    Topics: Animals; Cysteine; Cytosol; Deuterium; Kidney; Liver; Lysine; Magnetic Resonance Spectroscopy; Microsomes; Mitochondria; Rats; Rats, Inbred F344; Tritium

1992
Participation of bacteriorhodopsin active-site lysine backbone in vibrations associated with retinal photochemistry.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Mar-15, Volume: 89, Issue:6

    Topics: Bacteriorhodopsins; Binding Sites; Deuterium; Lysine; Photochemistry; Protein Conformation; Retinaldehyde; Spectrophotometry, Infrared

1992
Mechanism of the reaction catalyzed by mandelate racemase. 3. Asymmetry in reactions catalyzed by the H297N mutant.
    Biochemistry, 1991, Sep-24, Volume: 30, Issue:38

    Topics: Base Sequence; Bromides; Catalysis; Circular Dichroism; Deuterium; DNA Mutational Analysis; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Oligonucleotides; Racemases and Epimerases; Recombinant Proteins; Structure-Activity Relationship

1991
Incorporation of a stable isotopically labeled amino acid into multiple human apolipoproteins.
    Journal of lipid research, 1991, Volume: 32, Issue:7

    Topics: Adult; Apolipoproteins; Deuterium; Electrophoresis, Polyacrylamide Gel; Humans; Kinetics; Lysine; Male

1991
Characterization of an extremely large, ligand-induced conformational change in plasminogen.
    Science (New York, N.Y.), 1990, Apr-06, Volume: 248, Issue:4951

    Topics: Aminocaproic Acid; Binding Sites; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Deuterium; Humans; Lysine; Neutrons; Plasminogen; Plasminogen Activators; Protein Conformation; Scattering, Radiation; Urokinase-Type Plasminogen Activator; Water

1990
Comparison of deuterated leucine, valine, and lysine in the measurement of human apolipoprotein A-I and B-100 kinetics.
    Journal of lipid research, 1990, Volume: 31, Issue:9

    Topics: Adult; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins A; Apolipoproteins B; Deuterium; Humans; Kinetics; Leucine; Lipoproteins; Lysine; Valine

1990
Conformational changes of phospholipid headgroups induced by a cationic integral membrane peptide as seen by deuterium magnetic resonance.
    Biochemistry, 1989, Mar-07, Volume: 28, Issue:5

    Topics: Amino Acid Sequence; Cations; Deuterium; Dimyristoylphosphatidylcholine; Lipid Bilayers; Liposomes; Lysine; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Chemical; Molecular Sequence Data; Phosphatidylserines; Phospholipids; Protein Conformation

1989
Stereochemistry of lysine formation by meso-diaminopimelate decarboxylase from wheat germ: use of 1H-13C NMR shift correlation to detect stereospecific deuterium labeling.
    Biochemistry, 1985, Jun-18, Volume: 24, Issue:13

    Topics: Bacterial Proteins; Carboxy-Lyases; Deuterium; Isotope Labeling; Lysine; Magnetic Resonance Spectroscopy; Molecular Conformation; Seeds; Stereoisomerism; Triticum

1985
Protein conformational transitions in the erythrocyte membrane.
    Biochimica et biophysica acta, 1971, Jul-06, Volume: 241, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Alcohols; Caseins; Cell Membrane; Deuterium; Edetic Acid; Enzyme Activation; Erythrocytes; Freeze Drying; Humans; Hydrolysis; Infrared Rays; Inosine Nucleotides; Lysine; Magnesium; Myoglobin; Peptides; Phenylalanine; Phosphorus Isotopes; Potassium; Protein Conformation; Protein Hydrolysates; Serine; Sodium; Spectrophotometry

1971
Hypusine, a new amino acid occurring in bovine brain. Isolation and structural determination.
    Biochimica et biophysica acta, 1971, Sep-21, Volume: 244, Issue:3

    Topics: Amino Acids; Amino Alcohols; Animals; Brain Chemistry; Cattle; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Deuterium; Electrophoresis, Paper; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Optical Rotatory Dispersion; Oxidation-Reduction; Periodic Acid

1971
Carbon-13 NMR studies of peptide hormones and their components.
    Annals of the New York Academy of Sciences, 1973, Dec-31, Volume: 222

    Topics: Carbon Isotopes; Computers; Deuterium; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Fourier Analysis; Gonadotropin-Releasing Hormone; Hydrogen-Ion Concentration; Hypothalamus; Isomerism; Lysine; Magnetic Resonance Spectroscopy; Melanocyte-Stimulating Hormones; Oligopeptides; Oxytocin; Peptides; Peptides, Cyclic; Pituitary Hormone-Releasing Hormones; Proline; Structure-Activity Relationship; Thyrotropin-Releasing Hormone; Vasopressins

1973
Carbon-13 spin-lattice relaxation studies of intramolecular motion in lysine and a series of oligolysines.
    Archives of biochemistry and biophysics, 1974, Volume: 163, Issue:2

    Topics: Carbon Isotopes; Deuterium; Electron Spin Resonance Spectroscopy; Fourier Analysis; Hydrogen-Ion Concentration; Lysine; Mathematics; Molecular Conformation; Oligopeptides; Peptides; Structure-Activity Relationship

1974
Conformational mobility of the pyrrolidine ring of proline in peptides and peptide hormones as manifest in carbon 13 spin-lattice relaxation times.
    The Journal of biological chemistry, 1974, Nov-10, Volume: 249, Issue:21

    Topics: Amino Acid Sequence; Angiotensin II; Carbon Isotopes; Computers; Deuterium; Fourier Analysis; Gonadotropin-Releasing Hormone; Hormones; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Molecular Conformation; Oligopeptides; Oxytocin; Peptides; Peptides, Cyclic; Pituitary Hormone-Releasing Hormones; Proline; Protein Conformation; Structure-Activity Relationship; Thyrotropin-Releasing Hormone; Time Factors; Vasopressins

1974
Conformation of lysine vasopressin: a comparison with oxytocin.
    Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:7

    Topics: Deuterium; Dimethyl Sulfoxide; Lysine; Magnetic Resonance Spectroscopy; Oxytocin; Protein Conformation; Temperature; Vasopressins

1972
Proton magnetic resonance comparison of neurohypophyseal hormones and analogs: deletion of amino groups and the conformation of lysine vasopressin.
    Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:8

    Topics: Amino Acid Sequence; Deuterium; Lysine; Magnetic Resonance Spectroscopy; Oxytocin; Protein Conformation; Protons; Temperature; Vasopressins

1972
Nuclear magnetic resonance spectrum of lysine-vasopressin in aqueous solution and its structural implictions.
    Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:8

    Topics: Deuterium; Dimethyl Sulfoxide; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Protein Conformation; Solutions; Structure-Activity Relationship; Vasopressins; Water

1972
Method for correlation of proton magnetic resonance assignments in different solvents: conformational transition of oxytocin and lysine vasopressin from dimethylsulfoxide to water.
    Proceedings of the National Academy of Sciences of the United States of America, 1972, Volume: 69, Issue:9

    Topics: Deuterium; Dimethyl Sulfoxide; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Oxytocin; Protein Conformation; Solvents; Vasopressins; Water

1972
Conformational studies of oxytocin, lysine vasopressin, arginine vasopressin, and arginine vasotocin by carbon-13 nuclear magnetic resonance spectroscopy.
    Proceedings of the National Academy of Sciences of the United States of America, 1973, Volume: 70, Issue:7

    Topics: Arginine; Carbon Isotopes; Deuterium; Lysine; Magnetic Resonance Spectroscopy; Oxytocin; Protein Conformation; Vasopressins; Vasotocin

1973
Conformations and interactions of histones and their role in chromosome structure.
    Annals of the New York Academy of Sciences, 1973, Dec-31, Volume: 222

    Topics: Animals; Arginine; Binding Sites; Chickens; Chromatin; Chromosomes; Deuterium; DNA; Erythrocytes; Fourier Analysis; Gels; Histones; Lysine; Macromolecular Substances; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Optical Rotatory Dispersion; Osmolar Concentration; Protein Binding; Protein Conformation; Sodium Chloride; Temperature; Thymus Gland

1973
Effect of alanine, leucine and fructose on lysyl-transfer ribonucleic acid ligase activity in a mutant of Escherichia coli K-12.
    Journal of bacteriology, 1973, Volume: 113, Issue:1

    Topics: Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Carbohydrate Metabolism; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Culture Media; Deuterium; Escherichia coli; Fructose; Glucose; Leucine; Lysine; Mutation; Stereoisomerism; Stimulation, Chemical

1973
Basis of transport discrimination of arginine from other basic amino acids in Salmonella typhimurium.
    The Journal of biological chemistry, 1974, Nov-10, Volume: 249, Issue:21

    Topics: Alanine; Amino Acids; Arginine; Autoanalysis; Biological Transport; Carbon Radioisotopes; Chromatography, Ion Exchange; Deuterium; Glucose; Histidine; Homoserine; Hydroxyproline; Kinetics; Leucine; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Ornithine; Proline; Salmonella typhimurium; Structure-Activity Relationship; Tritium; Tryptophan

1974
The preparation and subsequent identification of a dehydroalanyl peptide from alkali-treated oxidised glutathione.
    Biochimica et biophysica acta, 1972, Dec-28, Volume: 285, Issue:2

    Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Deuterium; Dicarboxylic Acids; Dipeptides; Electrophoresis; Glutamates; Glutathione; Glycine; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Oligopeptides; Oxidation-Reduction; Proteins; Protons; Sulfides

1972
Infrared spectroscopy--conformation.
    Methods in enzymology, 1972, Volume: 26

    Topics: Amides; Caseins; Deuterium; Glycine; Hydrogen-Ion Concentration; Kinetics; Lactoglobulins; Lysine; Myoglobin; Peptides; Protein Conformation; Protein Denaturation; Spectrophotometry, Ultraviolet

1972
On the mechanism of action of streptococcal proteinase. 3. The effect of pH, organic solvents, and deuterium oxide on the proteinase-catalyzed hydrolysis of N-acylamino acid esters.
    Biochemistry, 1973, Jan-16, Volume: 12, Issue:2

    Topics: Acetates; Alanine; Amino Acids; Benzene Derivatives; Benzyl Compounds; Binding Sites; Binding, Competitive; Catalysis; Deuterium; Dimethyl Sulfoxide; Endopeptidases; Esters; Formates; Hydrogen-Ion Concentration; Kinetics; Lysine; Nitriles; Nitrobenzenes; Papain; Phosphates; Protease Inhibitors; Streptococcus; Tromethamine

1973
Carbon-13 nuclear magnetic resonance studies of polyamino acids: the helix-coil transition of poly-L-lysine.
    Archives of biochemistry and biophysics, 1973, Volume: 158, Issue:1

    Topics: Carbon Isotopes; Deuterium; Fourier Analysis; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Oligopeptides; Peptides; Protein Conformation; Temperature

1973
Nuclear magnetic resonance studies of the interaction of peptides and hormones with bovine neurophysin.
    Biochemistry, 1973, Nov-06, Volume: 12, Issue:23

    Topics: Animals; Binding Sites; Cattle; Deuterium; Hydrogen-Ion Concentration; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Molecular Conformation; Neurophysins; Nitrates; Oligopeptides; Oxytocin; Protein Binding; Protein Conformation; Vasopressins

1973
A quantitative study of organic phosphate-amine interaction by 31P nuclear magnetic resonance.
    Biochemical and biophysical research communications, 1974, May-07, Volume: 58, Issue:1

    Topics: Amines; Amino Acids; Binding Sites; Deuterium; Dipeptides; Dopamine; Epinephrine; Histamine; Histidine; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Molecular Conformation; Organophosphorus Compounds; Phosphorus Isotopes; Pyridoxine; Tyramine

1974
Interactions of aromatic residues of proteins with nucleic acids. I. Proton magnetic resonance studies of the binding of tryptophan-containing peptides to poly(adenylic acid) and deoxyribonucleic acid.
    Biochemistry, 1974, Feb-12, Volume: 13, Issue:4

    Topics: Adenine Nucleotides; Alanine; Animals; Binding Sites; Cattle; Cold Temperature; Deuterium; DNA; Glycine; Hydrogen-Ion Concentration; Indoles; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Methyl Ethers; Nucleic Acid Conformation; Oligopeptides; Osmolar Concentration; Polynucleotides; Protons; Serotonin; Sodium Chloride; Structure-Activity Relationship; Thymus Gland; Tryptamines; Tryptophan

1974
Interactions of aromatic residues of proteins with nucleic acid. II. Proton magnetic resonance studies of the binding of tyramine and tyrosine-containing peptides to poly(adenylic acid) and deoxyribonucleic acid.
    Biochemistry, 1974, Feb-12, Volume: 13, Issue:4

    Topics: Adenine Nucleotides; Amines; Animals; Cattle; Chemical Phenomena; Chemistry; Cold Temperature; Deuterium; DNA; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Methyl Ethers; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligopeptides; Osmolar Concentration; Polynucleotides; Protein Binding; Protons; Sodium Chloride; Structure-Activity Relationship; Thymus Gland; Tyramine; Tyrosine

1974
Ribosomal protein pool of Escherichia coli.
    Biochimica et biophysica acta, 1970, Aug-08, Volume: 213, Issue:2

    Topics: Ammonium Chloride; Bacterial Proteins; Carbon Isotopes; Centrifugation, Density Gradient; Chloramphenicol; Chlorides; Culture Media; Deuterium; Electrophoresis; Escherichia coli; Leucine; Lysine; Nitrogen Isotopes; Ribosomes; RNA, Ribosomal; Rubidium; Time Factors; Tritium; Uracil

1970
The reaction of amines with pyridoxal azomethines. The question of transaldimation and its role in the mechanism of vitamin B6 enzymes.
    Journal of the American Chemical Society, 1971, Volume: 93, Issue:22

    Topics: Aminobutyrates; Deuterium; Lysine; Magnetic Resonance Spectroscopy; Ornithine; Propionates; Pyridoxine; Schiff Bases; Transaminases

1971
Physicochemical properties of some acyl derivatives of -casein.
    Biochimica et biophysica acta, 1971, Aug-27, Volume: 243, Issue:2

    Topics: Acetates; Acylation; Anhydrides; Animals; Butyrates; Caseins; Cattle; Chemical Phenomena; Chemistry; Chemistry, Physical; Chromatography, DEAE-Cellulose; Deuterium; Electrophoresis; Fatty Acids; Female; Fluoroacetates; Hydrogen-Ion Concentration; Lysine; Macromolecular Substances; Magnetic Resonance Spectroscopy; Mathematics; Optical Rotatory Dispersion; Propionates; Protein Conformation; Temperature; Ultracentrifugation; Urea

1971
Nuclear magnetic resonance spectrum of lysine-vasopressin and its structural implications.
    Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:5

    Topics: Amino Acid Sequence; Deuterium; Dimethyl Sulfoxide; Lysine; Magnetic Resonance Spectroscopy; Peptides; Solutions; Temperature; Vasopressins

1971
Nuclear magnetic resonance studies of lysine-vasopressin: structural constraints.
    Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:12

    Topics: Chemical Phenomena; Chemistry; Deuterium; Infrared Rays; Isomerism; Lysine; Magnetic Resonance Spectroscopy; Peptides; Protein Conformation; Spectrum Analysis; Temperature; Vasopressins

1971
Lysine 2,3-aminomutase. Purification and properties of a pyridoxal phosphate and S-adenosylmethionine-activated enzyme.
    The Journal of biological chemistry, 1970, Apr-10, Volume: 245, Issue:7

    Topics: Acetone; Amino Acids; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Clostridium; Cysteine; Deuterium; Dialysis; Drug Stability; Electrophoresis; Electrophoresis, Disc; Enzyme Activation; Hydrogen-Ion Concentration; Hydroxylamines; Intramolecular Transferases; Iron; Isomerases; Isoniazid; Kinetics; Lysine; Methionine; Methods; Molecular Weight; Nucleosides; Pyridoxal Phosphate; Pyridoxine; Streptomycin; Sulfhydryl Compounds; Temperature; Tritium

1970
S methylation of thiols by O-methylisourea.
    Biochemistry, 1970, Aug-18, Volume: 9, Issue:17

    Topics: Acetates; Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Deuterium; Dipeptides; Ethanol; Glycine; Guanidines; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Mercaptoethanol; Methylation; Models, Biological; Sulfhydryl Compounds; Sulfhydryl Reagents; Time Factors; Urea

1970
The effect of substitution of deuterium oxide for water on very lysine-rich histone-deoxyribonucleic acid complexes.
    The Biochemical journal, 1970, Volume: 119, Issue:5

    Topics: Animals; Cattle; Deuterium; DNA; Histones; Lysine; Macromolecular Substances; Temperature; Water

1970
Effect of heavy water on the cell-free protein-synthesizing system.
    Biochimica et biophysica acta, 1968, May-21, Volume: 157, Issue:3

    Topics: Animals; Carbon Isotopes; Cell-Free System; Deuterium; Guinea Pigs; Liver; Lysine; Magnesium; Microsomes; Protein Biosynthesis; Temperature; Valine; Water

1968
Hydrogen-exchange studies of deoxyribonucleic acid-protein complexes. Development of a filtration method and application to the deoxyrubonucleic acid-polylysine system.
    Biochemistry, 1968, Volume: 7, Issue:7

    Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Deuterium; DNA; Filtration; Glass; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Lysine; Membranes, Artificial; Methods; Nucleic Acid Denaturation; Peptides; Thymus Gland; Tritium; Ultrasonics

1968
Helix-coil transition of polyl-glutamic acid and polyl-lysine in D2O.
    Biochemistry, 1965, Volume: 4, Issue:7

    Topics: Chemical Phenomena; Chemistry, Physical; Deuterium; Glutamates; Hydrogen-Ion Concentration; Lysine; Peptides

1965
The conformational transitions of uncharged poly-L-lysine. Alpha helix-random coil-beta structure.
    Biochemistry, 1967, Volume: 6, Issue:6

    Topics: Bromides; Chemical Phenomena; Chemistry, Physical; Deuterium; Electrons; Fluorides; Glycols; Hydrogen-Ion Concentration; Lithium; Lysine; Methanol; Peptides; Sodium Chloride; Solvents; Temperature; Thermodynamics

1967
Hydrogen-deuterium exchange studies on guanidinated pig heart lactate dehydrogenase.
    Biochimica et biophysica acta, 1983, Aug-16, Volume: 746, Issue:3

    Topics: Animals; Arginine; Deuterium; Drug Stability; Homoarginine; Hot Temperature; Kinetics; L-Lactate Dehydrogenase; Lysine; Myocardium; Protein Conformation; Swine; Tryptophan; Tyrosine

1983
Kinetic solvent isotope effects on the deacylation of specific acyl-papains. Proton inventory studies on the papain-catalysed hydrolyses of specific ester substrates: analysis of possible transition state structures.
    The Biochemical journal, 1981, Dec-01, Volume: 199, Issue:3

    Topics: Binding Sites; Deuterium; Dipeptides; Glycine; Kinetics; Lysine; Models, Biological; Papain; Protons

1981
Stereochemistry of meso-alpha,epsilon-diaminopimelate decarboxylase reaction: the first evidence for pyridoxal 5'-phosphate dependent decarboxylation with inversion of configuration.
    Biochemistry, 1981, Nov-24, Volume: 20, Issue:24

    Topics: Bacillus; Bacterial Proteins; Cadaverine; Carboxy-Lyases; Deuterium; Kinetics; Lysine; Piperidines; Pyridoxal Phosphate; Radioisotope Dilution Technique

1981
Pulsed electron paramagnetic resonance studies of the lysine 2,3-aminomutase substrate radical: evidence for participation of pyridoxal 5'-phosphate in a radical rearrangement.
    Biochemistry, 1995, Aug-08, Volume: 34, Issue:31

    Topics: Amino Acid Isomerases; Anions; Chlorides; Clostridium; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Intramolecular Transferases; Lysine; Models, Chemical; Pyridoxal Phosphate; Sulfates

1995
Decreasing the basicity of the active site base, Lys-258, of Escherichia coli aspartate aminotransferase by replacement with gamma-thialysine.
    Biochemistry, 1995, Mar-28, Volume: 34, Issue:12

    Topics: Amino Acid Sequence; Aspartate Aminotransferases; Binding Sites; Cysteine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lysine; Mathematics; Mutagenesis, Site-Directed; Recombinant Proteins; Spectrophotometry; Structure-Activity Relationship; Thermodynamics

1995
Topographic study of arrestin using differential chemical modifications and hydrogen/deuterium exchange.
    Protein science : a publication of the Protein Society, 1994, Volume: 3, Issue:12

    Topics: Acetylation; Amino Acid Sequence; Antigens; Arrestin; Deuterium; Eye Proteins; Heparin; Hydrogen; Lysine; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Photolysis; Protein Conformation; Rhodopsin

1994
Measurement of plasma protein synthesis rate in infant pig: an investigation of alternative tracer approaches.
    The American journal of physiology, 1994, Volume: 267, Issue:1 Pt 2

    Topics: Alanine; Animals; Animals, Newborn; Apolipoprotein B-100; Apolipoproteins B; Blood Proteins; Carbon Isotopes; Deuterium; Female; Fibrinogen; Leucine; Liver; Lysine; Male; Serum Albumin; Swine

1994
Effects of protein restriction and acute refeeding on leucine and lysine kinetics in young men.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: Adult; Carbon Isotopes; Deuterium; Dietary Proteins; Humans; Isotope Labeling; Keto Acids; Kinetics; Leucine; Lysine; Male; Nitrogen Isotopes; Protein Biosynthesis; Radioisotope Dilution Technique; Reference Values; Splanchnic Circulation

1993
Dietary lysine requirement of young adult males determined by oxidation of L-[1-13C]phenylalanine.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: Adult; Carbon Isotopes; Deuterium; Energy Intake; Humans; Isotope Labeling; Lysine; Male; Mathematics; Models, Biological; Nutritional Requirements; Oxidation-Reduction; Phenylalanine

1993
Alpha-(Ac)AKRHRKV, a model of the histone H4 amino terminus, uses an unprotonated histidine in phosphate binding.
    The journal of peptide research : official journal of the American Peptide Society, 1998, Volume: 51, Issue:2

    Topics: Amino Acid Sequence; Arginine; Deuterium; Histidine; Histones; Hydrogen Bonding; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligopeptides; Phosphates

1998
Structural stability and internal motions of Escherichia coli ribonuclease HI: 15N relaxation and hydrogen-deuterium exchange analyses.
    Journal of molecular biology, 1998, Apr-03, Volume: 277, Issue:3

    Topics: Amides; Deuterium; Escherichia coli; Glycine; Hydrogen; Hydrogen Bonding; Lysine; Mutagenesis, Site-Directed; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Ribonuclease H; Time Factors

1998
Vascular sources of phenylalanine, tyrosine, lysine, and methionine for casein synthesis in lactating goats.
    Journal of dairy science, 1999, Volume: 82, Issue:2

    Topics: Animals; Carbon Isotopes; Caseins; Deuterium; Female; Goats; Hydroxylation; Kinetics; Lactation; Lysine; Mammary Glands, Animal; Methionine; Phenylalanine; Tyrosine

1999
Raman markers of nonaromatic side chains in an alpha-helix assembly: Ala, Asp, Glu, Gly, Ile, Leu, Lys, Ser, and Val residues of phage fd subunits.
    Biochemistry, 1999, Mar-30, Volume: 38, Issue:13

    Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Deuterium; DNA, Single-Stranded; Glutamic Acid; Glycine; Inovirus; Isoleucine; Lysine; Molecular Sequence Data; Protein Structure, Secondary; Serine; Spectrum Analysis, Raman; Valine; Viral Proteins; Virus Assembly

1999
Lysine 183 is the general base in the 6-phosphogluconate dehydrogenase-catalyzed reaction.
    Biochemistry, 1999, Aug-31, Volume: 38, Issue:35

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Catalysis; Deuterium; Hydrogen-Ion Concentration; Kinetics; Liver; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphogluconate Dehydrogenase; Recombinant Proteins; Sheep

1999
Roles of tyrosine 158 and lysine 165 in the catalytic mechanism of InhA, the enoyl-ACP reductase from Mycobacterium tuberculosis.
    Biochemistry, 1999, Oct-12, Volume: 38, Issue:41

    Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Catalysis; Circular Dichroism; Deuterium; Histidine; Kinetics; Lysine; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; NAD; Oxidoreductases; Peptide Fragments; Recombinant Proteins; Solvents; Tyrosine

1999
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
    Biochemistry, 2000, Aug-08, Volume: 39, Issue:31

    Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan

2000
Lysine 2,3-aminomutase and trans-4,5-dehydrolysine: characterization of an allylic analogue of a substrate-based radical in the catalytic mechanism.
    Biochemistry, 2000, Aug-08, Volume: 39, Issue:31

    Topics: Binding Sites; Catalysis; Clostridium; Deuterium; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Enzyme Stability; Free Radicals; Hydrolysis; Intramolecular Transferases; Lysine; Molecular Conformation; S-Adenosylmethionine; Substrate Specificity

2000
Identification of active site residues in E. coli ketopantoate reductase by mutagenesis and chemical rescue.
    Biochemistry, 2000, Dec-26, Volume: 39, Issue:51

    Topics: Acetic Acid; Alanine; Alcohol Oxidoreductases; Alkylation; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Cysteine; Deuterium; Escherichia coli; Formates; Gene Expression Regulation, Bacterial; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Pantothenic Acid; Recombinant Proteins; Sequence Alignment; Substrate Specificity

2000
Investigation of allosteric linkages in the regulation of tryptophan synthase: the roles of salt bridges and monovalent cations probed by site-directed mutation, optical spectroscopy, and kinetics.
    Biochemistry, 2001, Mar-27, Volume: 40, Issue:12

    Topics: Alanine; Allosteric Regulation; Asparagine; Aspartic Acid; Cations, Monovalent; Deuterium; Dimerization; Enzyme Activation; Kinetics; Lysine; Multienzyme Complexes; Mutagenesis, Site-Directed; Potassium; Quaternary Ammonium Compounds; Salmonella typhimurium; Salts; Sodium; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Threonine; Titrimetry; Tryptophan Synthase

2001
Conformational changes of the ferric uptake regulation protein upon metal activation and DNA binding; first evidence of structural homologies with the diphtheria toxin repressor.
    Journal of molecular biology, 2001, Jun-29, Volume: 310, Issue:1

    Topics: Amino Acid Sequence; Apoproteins; Bacterial Proteins; Deuterium; DNA; DNA-Binding Proteins; Helix-Turn-Helix Motifs; Imidoesters; Iron; Lysine; Manganese; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Repressor Proteins; Sequence Alignment; Spectrometry, Mass, Electrospray Ionization

2001
A ruthenium(II) tris(bipyridyl) amino acid: synthesis and direct incorporation into an alpha-helical peptide by solid-phase synthesis.
    Inorganic chemistry, 2002, Jan-28, Volume: 41, Issue:2

    Topics: 2,2'-Dipyridyl; Alanine; Algorithms; Amino Acid Sequence; Amino Acids; Catalysis; Circular Dichroism; Deuterium; Histidine; Hydrogen; Lysine; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Organometallic Compounds; Peptides; Ruthenium; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Temperature; Time Factors

2002
Vascular sources of amino acids for milk protein synthesis in goats at two stages of lactation.
    Journal of dairy science, 2002, Volume: 85, Issue:4

    Topics: Amino Acids; Animals; Carbon Isotopes; Caseins; Deuterium; Female; Goats; Kinetics; Lactation; Lysine; Mammary Glands, Animal; Methionine; Milk Proteins; Regional Blood Flow; Time Factors

2002
Analysis of carnitine biosynthesis metabolites in urine by HPLC-electrospray tandem mass spectrometry.
    Clinical chemistry, 2002, Volume: 48, Issue:6 Pt 1

    Topics: Carnitine; Chromatography, High Pressure Liquid; Deuterium; Humans; Infant, Newborn; Lysine; Male; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2002
Mousy off-flavor of wine: precursors and biosynthesis of the causative N-heterocycles 2-ethyltetrahydropyridine, 2-acetyltetrahydropyridine, and 2-acetyl-1-pyrroline by Lactobacillus hilgardii DSM 20176.
    Journal of agricultural and food chemistry, 2002, Nov-20, Volume: 50, Issue:24

    Topics: Acetaldehyde; Acylation; Cations, Divalent; Deuterium; Ethanol; Fructose; Heterocyclic Compounds; Lactobacillus; Lysine; Metals; Ornithine; Pyridines; Pyrroles; Taste; Wine

2002
Use of deuterium-labeled lysine for efficient protein identification and peptide de novo sequencing.
    Analytical chemistry, 2002, Nov-15, Volume: 74, Issue:22

    Topics: Algorithms; Amino Acid Sequence; Databases, Factual; Deuterium; DNA-Binding Proteins; Humans; Hydrolysis; Isotope Labeling; Lysine; Molecular Sequence Data; Myogenic Regulatory Factors; Peptide Mapping; Peptides; Proteins; Sequence Analysis; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transcription Factors; Trypsin

2002
Protein hydrogen exchange mechanism: local fluctuations.
    Protein science : a publication of the Protein Society, 2003, Volume: 12, Issue:1

    Topics: Amides; Amino Acid Substitution; Animals; Cytochrome c Group; Deuterium; Glycine; Horses; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Lysine; Motion; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Denaturation; Protons; Recombinant Proteins; Solvents; Thermodynamics

2003
Homochiral oligopeptides by chiral amplification within two-dimensional crystalline self-assemblies at the air-water interface; relevance to biomolecular handedness.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2003, Apr-14, Volume: 9, Issue:8

    Topics: Air; Crystallization; Deuterium; Glutamic Acid; Lysine; Models, Molecular; Oligopeptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Surface Properties; Water; X-Ray Diffraction

2003
New substrates for beta-lactam-recognizing enzymes: aryl malonamates.
    Biochemistry, 2003, Jun-10, Volume: 42, Issue:22

    Topics: Acylation; Amides; beta-Lactamases; Catalysis; Deuterium; Enterobacter cloacae; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lysine; Malonates; Models, Molecular; Substrate Specificity

2003
On the role of Brønsted catalysis in Pseudomonas fluorescens mannitol 2-dehydrogenase.
    The Biochemical journal, 2003, Oct-01, Volume: 375, Issue:Pt 1

    Topics: Alcohol Oxidoreductases; Amines; Catalysis; Deuterium; Hydrogen-Ion Concentration; Kinetics; Lysine; Mannitol; Mannitol Dehydrogenases; Models, Chemical; Mutation; Oxidation-Reduction; Pseudomonas fluorescens; Solvents

2003
Complete reversal of coenzyme specificity by concerted mutation of three consecutive residues in alcohol dehydrogenase.
    The Journal of biological chemistry, 2003, Oct-17, Volume: 278, Issue:42

    Topics: Alcohol Dehydrogenase; Animals; Binding Sites; Catalysis; Computer Simulation; Deuterium; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NADP; Protein Binding; Ranidae; Time Factors

2003
A novel lipid hydroperoxide-derived cyclic covalent modification to histone H4.
    The Journal of biological chemistry, 2003, Oct-24, Volume: 278, Issue:43

    Topics: Aldehydes; Amino Acid Sequence; Animals; Carbon Isotopes; Cattle; Cyclization; Deuterium; Histidine; Histones; Lipid Peroxides; Lysine; Peptides, Cyclic; Spectrometry, Mass, Electrospray Ionization

2003
Role of Arg100 in the active site of adenosylcobalamin-dependent glutamate mutase.
    Biochemistry, 2004, Mar-23, Volume: 43, Issue:11

    Topics: Arginine; Bacterial Proteins; Binding Sites; Catalysis; Cobamides; Deuterium; Glutamic Acid; Hydrogen Bonding; Intramolecular Transferases; Kinetics; Lysine; Mutagenesis, Site-Directed; N-Methylaspartate; Spectrophotometry; Substrate Specificity; Vitamin B 12

2004
Quantification of acetylation at proximal lysine residues using isotopic labeling and tandem mass spectrometry.
    Methods (San Diego, Calif.), 2005, Volume: 36, Issue:4

    Topics: Acetic Acid; Acetylation; Chromatography, High Pressure Liquid; Deuterium; Histones; Ions; Isotope Labeling; Lysine; Mass Spectrometry; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Statistics as Topic; Trypsin; Yeasts

2005
Accelerated on-column lysine derivatization and cysteine methylation by imidazole reaction in a deuterated environment for enhanced product ion analysis.
    Rapid communications in mass spectrometry : RCM, 2006, Volume: 20, Issue:4

    Topics: Amino Acid Sequence; Cysteine; Deuterium; Erythropoietin; Humans; Imidazoles; Interferon alpha-2; Interferon-alpha; Lysine; Metalloendopeptidases; Methylation; Molecular Sequence Data; Molecular Structure; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Trypsin

2006
Changes in secondary structures and acidic side chains of melibiose permease upon cosubstrates binding.
    Biophysical journal, 2006, Dec-15, Volume: 91, Issue:12

    Topics: Amino Acid Motifs; Deuterium; Escherichia coli Proteins; Liposomes; Lysine; Melibiose; Protein Binding; Protein Structure, Secondary; Sodium; Spectroscopy, Fourier Transform Infrared; Substrate Specificity; Symporters; Water

2006
Mass spectrometry-based glycoproteomic approach involving lysine derivatization for structural characterization of recombinant human erythropoietin.
    Journal of proteome research, 2006, Volume: 5, Issue:11

    Topics: Amino Acid Sequence; Cysteine; Deuterium; Erythropoietin; Glycoproteins; Glycosylation; Humans; Lysine; Molecular Sequence Data; Peptide Fragments; Polysaccharides; Proteomics; Recombinant Proteins; Trypsin

2006
Quantitative profiling of histone post-translational modifications by stable isotope labeling.
    Methods (San Diego, Calif.), 2007, Volume: 41, Issue:3

    Topics: Animals; Cells, Cultured; Chromatin Assembly and Disassembly; Deuterium; Histones; Lysine; Mammals; Mass Spectrometry; Molecular Weight; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2007
Rate-limiting steps and role of active site Lys443 in the mechanism of carbapenam synthetase.
    Biochemistry, 2007, Aug-14, Volume: 46, Issue:32

    Topics: Alanine; Binding Sites; Carbon-Nitrogen Ligases; Catalysis; Deuterium; Enzyme Activation; Escherichia coli Proteins; Genetic Variation; Hydrogen-Ion Concentration; Kinetics; Lysine; Solvents; Substrate Specificity; Viscosity

2007
Helical distortion in tryptophan- and lysine-anchored membrane-spanning alpha-helices as a function of hydrophobic mismatch: a solid-state deuterium NMR investigation using the geometric analysis of labeled alanines method.
    Biophysical journal, 2008, Jan-15, Volume: 94, Issue:2

    Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Deuterium; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Lipid Metabolism; Lysine; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Structure, Secondary; Staining and Labeling; Tryptophan

2008
Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins.
    Journal of molecular biology, 2008, Jan-25, Volume: 375, Issue:4

    Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Carrier Proteins; Deuterium; DNA-Binding Proteins; Dose-Response Relationship, Drug; Glutathione Transferase; Glycine; Guanidine; Humans; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ligands; Lysine; Models, Molecular; Mutation; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; Substrate Specificity; Temperature; Thermodynamics; Ubiquitin; Ubiquitination

2008
Characterization of salt bridges to lysines in the protein G B1 domain.
    Journal of the American Chemical Society, 2009, Apr-08, Volume: 131, Issue:13

    Topics: Aspartic Acid; Bacterial Proteins; Deuterium; Escherichia coli; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Nerve Tissue Proteins; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; Quantum Theory; Salts; Streptococcus

2009
Site-directed mutagenesis as a probe of the acid-base catalytic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
    Biochemistry, 2009, Aug-04, Volume: 48, Issue:30

    Topics: Alcohol Oxidoreductases; Catalysis; Deuterium; Hydrogen-Ion Concentration; Lysine; Molecular Structure; Mutagenesis, Site-Directed; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Solvents; Tyrosine; Viscosity

2009
A solid-state deuterium NMR and sum-frequency generation study of the side-chain dynamics of peptides adsorbed onto surfaces.
    Journal of the American Chemical Society, 2009, Oct-14, Volume: 131, Issue:40

    Topics: Adsorption; Amino Acid Sequence; Deuterium; Hydrophobic and Hydrophilic Interactions; Leucine; Lysine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Peptides

2009
Control of lysyl oxidase activity through site-specific deuteration of lysine.
    Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1

    Topics: Animals; Deuterium; Isotope Labeling; Kinetics; Lysine; Mice; Oxidation-Reduction; Protein-Lysine 6-Oxidase; Recombinant Proteins; Sheep; Substrate Specificity

2011
Suppression of isotope scrambling in cell-free protein synthesis by broadband inhibition of PLP enymes for selective 15N-labelling and production of perdeuterated proteins in H2O.
    Journal of biomolecular NMR, 2011, Volume: 50, Issue:1

    Topics: Cell-Free System; Deuterium; Isotope Labeling; Lysine; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Biosynthesis; Proteins; Pyridoxal Phosphate; Water

2011
Ab initio calculations of deuterium isotope effects on chemical shifts of salt-bridged lysines.
    The journal of physical chemistry. B, 2011, Mar-31, Volume: 115, Issue:12

    Topics: Deuterium; Lysine; Models, Molecular; Nerve Tissue Proteins; Protein Structure, Tertiary; Quantum Theory; Water

2011
Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae.
    Biochemistry, 2012, Jan-31, Volume: 51, Issue:4

    Topics: Amino Acid Substitution; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Deuterium; Enzyme Stability; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; NAD; Protein Conformation; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Saccharopine Dehydrogenases; Viscosity

2012
Structure-function relationship of Vibrio harveyi NADPH-flavin oxidoreductase FRP: essential residues Lys167 and Arg15 for NADPH binding.
    Biochemistry, 2012, Jun-19, Volume: 51, Issue:24

    Topics: Amino Acid Sequence; Anaerobiosis; Arginine; Deuterium; FMN Reductase; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; Oxidation-Reduction; Protein Binding; Protein Conformation; Structure-Activity Relationship; Substrate Specificity; Vibrio

2012
The carnitine biosynthetic pathway in Arabidopsis thaliana shares similar features with the pathway of mammals and fungi.
    Plant physiology and biochemistry : PPB, 2012, Volume: 60

    Topics: Animals; Arabidopsis; Betaine; Biosynthetic Pathways; Carnitine; Chromatography, Liquid; Deuterium; Fungi; Lipid Metabolism; Lysine; Mammals; Plant Extracts; Seedlings; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Vitamin B Complex

2012
Plant SILAC: stable-isotope labelling with amino acids of arabidopsis seedlings for quantitative proteomics.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Arginine; Carbon Isotopes; Cell Culture Techniques; Deuterium; Gene Expression Regulation, Plant; Isotope Labeling; Lysine; Molecular Sequence Data; Proteomics; Salinity; Seedlings; Sodium Chloride; Stress, Physiological

2013
Detection of salt bridges to lysines in solution in barnase.
    Chemical communications (Cambridge, England), 2013, Oct-28, Volume: 49, Issue:84

    Topics: Bacterial Proteins; Deuterium; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Reference Standards; Ribonucleases; Salts; Solutions

2013
Role of choline and glycine betaine in the formation of N,N-dimethylpiperidinium (mepiquat) under Maillard reaction conditions.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2014, Volume: 31, Issue:12

    Topics: Alkaloids; Betaine; Carbon Radioisotopes; Choline; Chromatography, High Pressure Liquid; Deuterium; Hot Temperature; Kinetics; Lysine; Maillard Reaction; Methylation; Models, Chemical; Molecular Structure; Molecular Weight; Piperidines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2014
A strong developmental isotope effect in Caenorhabditis elegans induced by 5,5-deuterated lysine.
    Amino acids, 2017, Volume: 49, Issue:5

    Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Deuterium; Eating; Escherichia coli; Gene Expression Regulation, Developmental; Larva; Lysine; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; RNA, Small Interfering; Structure-Activity Relationship; Temperature

2017
MdFDIA: A Mass Defect Based Four-Plex Data-Independent Acquisition Strategy for Proteome Quantification.
    Analytical chemistry, 2017, 10-03, Volume: 89, Issue:19

    Topics: Amino Acids; Carbon Isotopes; Chromatography, High Pressure Liquid; Databases, Factual; Deuterium; Humans; Isotope Labeling; Lysine; MCF-7 Cells; Nitrogen Isotopes; Proteome; Tandem Mass Spectrometry

2017
Stereoselective Deuteration in Aspartate, Asparagine, Lysine, and Methionine Amino Acid Residues Using Fumarate as a Carbon Source for Escherichia coli in D
    Biochemistry, 2017, 11-14, Volume: 56, Issue:45

    Topics: Amino Acids; Asparagine; Aspartic Acid; Carbon; Culture Media; Deuterium; Escherichia coli; Fumarates; Humans; Lysine; Methionine; Models, Molecular; Mutant Proteins; NIMA-Interacting Peptidylprolyl Isomerase; Stereoisomerism

2017
Stable Deuterium Labeling of Histidine-Rich Lysine-Based Dendrimers.
    Molecules (Basel, Switzerland), 2019, Jul-06, Volume: 24, Issue:13

    Topics: Dendrimers; Deuterium; Histidine; Hydrogen; Isotope Labeling; Lysine; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular

2019
Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry.
    Nature communications, 2022, 10-06, Volume: 13, Issue:1

    Topics: Cullin Proteins; Deuterium; Lysine; Mass Spectrometry; Molecular Dynamics Simulation; Proteolysis; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination

2022