deuterium has been researched along with linoleic acid in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.00) | 18.7374 |
| 1990's | 12 (30.00) | 18.2507 |
| 2000's | 10 (25.00) | 29.6817 |
| 2010's | 13 (32.50) | 24.3611 |
| 2020's | 3 (7.50) | 2.80 |
| Authors | Studies |
|---|---|
| Adlof, RO; Emken, EA; Gulley, RM; Rakoff, H; Rohwedder, WK | 2 |
| Adlof, RO; Brown-Booth, L; Emken, EA; Garza, C; Hachey, DL; Klein, PD; Thomas, MR | 1 |
| Doan, BT; Gillet, B | 1 |
| Barnes, A; Pawlosky, R; Salem, N | 1 |
| Adlof, RO; Emken, EA; Gulley, RM | 1 |
| Brodowsky, ID; Hamberg, M; Oliw, EH; Zhang, LY | 1 |
| Cowling, RA; Nelson, MJ; Seitz, SP | 1 |
| Adlof, RO; Emken, EA; Gulley, RM; Rohwedder, WK | 1 |
| Luthria, DL; Sprecher, H | 1 |
| Pawlosky, RJ; Salem, N; Ward, G | 1 |
| Glickman, MH; Klinman, JP | 1 |
| Adlof, RO; Duval, SM; Emken, EA; Nelson, GJ | 1 |
| Klinman, JP; Rickert, KW | 1 |
| Blohm, FY; DeLany, JP; Truett, AA; West, DB | 1 |
| Adlof, RO; Benito, P; Duval, S; Emken, EA; Nelson, G | 1 |
| Buist, PH; Covello, PS; Qiu, X; Reed, DW; Savile, CK | 1 |
| Clandinin, MT; French, MA; Sundram, K | 1 |
| Peng, S; van der Donk, WA | 1 |
| Lin, YH; Pawlosky, RJ; Salem, N | 1 |
| Lin, YH; Salem, N | 2 |
| Li, Y; Lin, Y; Llanos, A; Mena, P; Salem, N; Uauy, R | 1 |
| Brinkley, DW; Chang, KM; Mukherjee, A; Roth, JP | 1 |
| Billault, I; Lesot, P; Martel, L; Serhan, Z | 1 |
| Hamberg, M | 1 |
| Cantor, CR; Chou, VP; Langston, JW; Manning-Boğ, AB; Molinari, RJ; Pollock, E; Shchepinov, MS | 1 |
| Billault, I; Le Du, A; Lesot, P; Ouethrani, M; Robins, RJ; Serhan, Z | 1 |
| Awad, AM; Bekish, AV; Cantor, CR; Clarke, CF; Hill, S; Lamberson, CR; Marbois, BN; Porter, NA; Shchepinov, MS; Shmanai, VV; To, R; Tsui, HS; Xu, L | 1 |
| Karkehabadi, S; Oliw, EH; Wennman, A | 1 |
| Brand, A; Lin, YH; Salem, N; Yavin, E | 1 |
| Debrota, J; Iyengar, SS; Li, J; Phatak, P; Venderley, J | 1 |
| Liu, Y; Roth, JP | 1 |
| Cerrate, S; Coon, CN; Ekmay, RD; England, JA; Salas, C | 1 |
| Dennis, EA; Navratil, AR; Shchepinov, MS | 1 |
| Cantor, CR; Chesselet, MF; Elias, C; Galstyan, A; Hatami, A; Jun, M; Milne, G; Relaño-Gines, A; Shchepinov, MS; Zhu, C | 1 |
| Ewing, AG; Malmberg, P; Philipsen, MH; Sämfors, S | 1 |
| Beal, MF; Calingasan, NY; Chiluwal, J; Milne, GL; Shchepinov, MS; Tapias, V | 1 |
| Gudkov, SV; Plotnikov, EY; Turovsky, EA; Varlamova, EG | 1 |
| Fujiwara, Y; Hama, K; Murata, S; Takita, R; Watanabe, A; Watanabe, K; Yokoyama, K | 1 |
1 trial(s) available for deuterium and linoleic acid
| Article | Year |
|---|---|
Cholesterolaemic effect of palmitic acid in relation to other dietary fatty acids.
Topics: Adult; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Deuterium; Female; Humans; Hypercholesterolemia; Linoleic Acid; Male; Mass Spectrometry; Palmitic Acid | 2002 |
39 other study(ies) available for deuterium and linoleic acid
| Article | Year |
|---|---|
Metabolism in vivo of deuterium-labelled linolenic and linoleic acids in humans.
Topics: Adult; Deuterium; Dietary Fats; Fatty Acids, Essential; Fatty Acids, Unsaturated; Humans; Kinetics; Linoleic Acid; Linoleic Acids; Linolenic Acids; Male; Radioisotope Dilution Technique; Time Factors | 1990 |
Metabolism in humans of cis-12,trans-15-octadecadienoic acid relative to palmitic, stearic, oleic and linoleic acids.
Topics: Adult; Cholesterol Esters; Chylomicrons; Deuterium; Dietary Fats; Fatty Acids, Unsaturated; Gas Chromatography-Mass Spectrometry; Humans; Linoleic Acid; Linoleic Acids; Male; Oleic Acid; Oleic Acids; Palmitic Acid; Palmitic Acids; Phospholipids; Radioisotope Dilution Technique; Stearic Acids; Triglycerides | 1987 |
Human lactation: maternal transfer of dietary triglycerides labeled with stable isotopes.
Topics: Adult; Biological Transport; Chromatography, Gas; Deuterium; Dietary Fats; Female; Humans; Lactation; Linoleic Acid; Linoleic Acids; Milk, Human; Oleic Acid; Oleic Acids; Palmitic Acid; Palmitic Acids; Pregnancy; Triglycerides | 1987 |
Phase-sensitive two-dimensional experiment on living animals.
Topics: Animals; Carnosine; Deuterium; Fatty Acids; Hindlimb; Hydrogen; Image Enhancement; Lactates; Linoleic Acid; Linoleic Acids; Magnetic Resonance Spectroscopy; Mice; Muscle, Skeletal; Phosphatidylcholines; Taurine; Triglycerides | 1995 |
Essential fatty acid metabolism in the feline: relationship between liver and brain production of long-chain polyunsaturated fatty acids.
Topics: alpha-Linolenic Acid; Animals; Arachidonic Acid; Brain; Cats; Coconut Oil; Corn Oil; Deuterium; Dietary Fats, Unsaturated; Fatty Acid Desaturases; Fatty Acids; Fatty Acids, Essential; Fatty Acids, Unsaturated; Gas Chromatography-Mass Spectrometry; Linoleic Acid; Linoleic Acids; Liver; Male; Plant Oils | 1994 |
Dietary linoleic acid influences desaturation and acylation of deuterium-labeled linoleic and linolenic acids in young adult males.
Topics: Acylation; Adult; alpha-Linolenic Acid; Deuterium; Dietary Fats; Diglycerides; Humans; Linoleic Acid; Linoleic Acids; Lipids; Male; Phosphatidylcholines; Phosphatidylethanolamines | 1994 |
Sequential oxygenation of linoleic acid in the fungus Gaeumannomyces graminis: stereochemistry of dioxygenase and hydroperoxide isomerase reactions.
Topics: Deuterium; Intramolecular Oxidoreductases; Isomerases; Linoleic Acid; Linoleic Acids; Molecular Conformation; Oxidation-Reduction; Xylariales | 1994 |
Structural characterization of alkyl and peroxyl radicals in solutions of purple lipoxygenase.
Topics: Color; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Linoleic Acid; Linoleic Acids; Lipoxygenase; Peroxides; Solutions | 1994 |
Influence of linoleic acid on desaturation and uptake of deuterium-labeled palmitic and stearic acids in humans.
Topics: Adult; Chylomicrons; Deuterium; Dietary Fats, Unsaturated; Fatty Acid Desaturases; Fatty Acids, Unsaturated; Humans; Hypercholesterolemia; Intestinal Absorption; Linoleic Acid; Linoleic Acids; Lipids; Male; Oleic Acid; Oleic Acids; Palmitic Acid; Palmitic Acids; Phosphatidylcholines; Stearic Acids; Stearoyl-CoA Desaturase; Temperature; Time Factors; Triglycerides | 1993 |
Metabolism of deuterium-labeled linoleic, 6,9,12-octadecatrienoic, 8,11,14-eicosatrienoic, and arachidonic acids in the rat.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Chromatography, High Pressure Liquid; Deuterium; Esterification; gamma-Linolenic Acid; Kidney; Linoleic Acid; Linoleic Acids; Liver; Male; Myocardium; Phospholipids; Rats; Rats, Sprague-Dawley | 1995 |
Essential fatty acid uptake and metabolism in the developing rodent brain.
Topics: Administration, Oral; alpha-Linolenic Acid; Animals; Animals, Suckling; Brain; Deuterium; Fatty Acids, Essential; Gas Chromatography-Mass Spectrometry; Linoleic Acid; Linoleic Acids; Liver; Mice; Rats | 1996 |
Lipoxygenase reaction mechanism: demonstration that hydrogen abstraction from substrate precedes dioxygen binding during catalytic turnover.
Topics: Catalysis; Deuterium; Free Radicals; Glycine max; Hydrogen; Kinetics; Linoleic Acid; Linoleic Acids; Lipid Peroxides; Lipoxygenase; Models, Chemical; Oxygen; Protein Binding | 1996 |
Effect of dietary arachidonic acid on metabolism of deuterated linoleic acid by adult male subjects.
Topics: Administration, Oral; Adult; Arachidonic Acid; Cholesterol; Cholesterol Esters; Deuterium; Dietary Fats; Humans; Linoleic Acid; Lipids; Male; Phospholipids; Triglycerides | 1998 |
Nature of hydrogen transfer in soybean lipoxygenase 1: separation of primary and secondary isotope effects.
Topics: Catalysis; Deuterium; Electron Transport; Glycine max; Hydrogen; Kinetics; Linoleic Acid; Lipoxygenase; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Plant Proteins; Stereoisomerism | 1999 |
Conjugated linoleic acid persistently increases total energy expenditure in AKR/J mice without increasing uncoupling protein gene expression.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Blood Glucose; Blotting, Northern; Carrier Proteins; Deuterium; Energy Intake; Energy Metabolism; Fatty Acids; Gene Expression; Human Growth Hormone; Insulin; Ion Channels; Linoleic Acid; Male; Membrane Proteins; Membrane Transport Proteins; Mice; Mice, Inbred AKR; Mitochondrial Proteins; Organ Size; Proteins; Uncoupling Protein 1; Uncoupling Protein 2 | 2000 |
Effect of dietary conjugated linoleic acid (CLA) on metabolism of isotope-labeled oleic, linoleic, and CLA isomers in women.
Topics: Adsorption; Adult; Area Under Curve; Deuterium; Dietary Fats, Unsaturated; Female; Humans; Isomerism; Linoleic Acid; Lipids; Oleic Acid; Time Factors | 2002 |
Mechanism of 1,4-dehydrogenation catalyzed by a fatty acid (1,4)-desaturase of Calendula officinalis.
Topics: Biochemistry; Calendula; Catalysis; Deuterium; Fatty Acid Desaturases; Isotope Labeling; Linoleic Acid; Linoleic Acids; Oxidation-Reduction; Saccharomyces cerevisiae | 2002 |
An unusual isotope effect on substrate inhibition in the oxidation of arachidonic acid by lipoxygenase.
Topics: Arachidonic Acid; Deuterium; Glycine max; Hydroxyeicosatetraenoic Acids; Kinetics; Linoleic Acid; Lipoxygenase; Lipoxygenase Inhibitors; Oxidation-Reduction | 2003 |
Simultaneous quantitative determination of deuterium- and carbon-13-labeled essential fatty acids in rat plasma.
Topics: alpha-Linolenic Acid; Animals; Arachidonic Acid; Carbon Isotopes; Chromatography, Gas; Deuterium; Docosahexaenoic Acids; Fatty Acids, Essential; Female; Gas Chromatography-Mass Spectrometry; Isotope Labeling; Linoleic Acid; Male; Rats; Rats, Sprague-Dawley | 2005 |
In vivo conversion of 18- and 20-C essential fatty acids in rats using the multiple simultaneous stable isotope method.
Topics: alpha-Linolenic Acid; Animals; Arachidonic Acid; Carbon Isotopes; Deuterium; Dietary Fats; Fatty Acids; Fatty Acids, Essential; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Isotope Labeling; Kinetics; Linoleic Acid; Male; Rats; Rats, Sprague-Dawley | 2005 |
Infants with intrauterine growth restriction have impaired formation of docosahexaenoic acid in early neonatal life: a stable isotope study.
Topics: alpha-Linolenic Acid; Area Under Curve; Birth Weight; Deuterium; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Fatty Acids, Unsaturated; Fetal Growth Retardation; Humans; Infant, Newborn; Isotopes; Linoleic Acid; Time Factors | 2005 |
Molecular oxygen dependent steps in fatty acid oxidation by cyclooxygenase-1.
Topics: Animals; Arachidonic Acid; Cyclooxygenase 1; Deuterium; Fatty Acids, Unsaturated; Kinetics; Linoleic Acid; Male; Models, Chemical; Models, Molecular; Oxidation-Reduction; Oxygen; Peroxides; Sheep | 2007 |
Whole body distribution of deuterated linoleic and alpha-linolenic acids and their metabolites in the rat.
Topics: alpha-Linolenic Acid; Animals; Deuterium; Deuterium Exchange Measurement; Dietary Fats, Unsaturated; Female; Gas Chromatography-Mass Spectrometry; Linoleic Acid; Male; Rats; Rats, Long-Evans; Time Factors; Tissue Distribution | 2007 |
Complete determination of natural site-specific enantio-isotopomeric excesses in linoleic acid using natural abundance deuterium 2D NMR in polypeptide mesophases.
Topics: Deuterium; Linoleic Acid; Magnetic Resonance Spectroscopy; Peptides; Polyglutamic Acid; Pyridines; Stereoisomerism | 2010 |
Stereochemistry of hydrogen removal during oxygenation of linoleic acid by singlet oxygen and synthesis of 11(S)-deuterium-labeled linoleic acid.
Topics: Chromatography, High Pressure Liquid; Deuterium; Hydrogen; Hydrogen Peroxide; Linoleic Acid; Oxygen; Singlet Oxygen; Stereoisomerism | 2011 |
Isotopic reinforcement of essential polyunsaturated fatty acids diminishes nigrostriatal degeneration in a mouse model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; alpha-Linolenic Acid; Animals; Cell Death; Corpus Striatum; Deuterium; Disease Models, Animal; Fatty Acids, Unsaturated; Linoleic Acid; Mice; Mice, Inbred C57BL; Nerve Degeneration; Oleic Acid; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Substantia Nigra | 2011 |
Probing substrate-product relationships by natural abundance deuterium 2D NMR spectroscopy in liquid-crystalline solvents: epoxidation of linoleate to vernoleate by two different plant enzymes.
Topics: Cytochrome P-450 Enzyme System; Deuterium; Dioxygenases; Epoxy Compounds; Euphorbia; Linoleic Acid; Liquid Crystals; Magnetic Resonance Spectroscopy; Molecular Structure; Oleic Acids; Oxidation-Reduction; Plant Oils; Plant Proteins; Solvents; Substrate Specificity; Vernonia | 2012 |
Small amounts of isotope-reinforced polyunsaturated fatty acids suppress lipid autoxidation.
Topics: Antioxidants; Arachidonic Acid; Copper; Deuterium; Eicosapentaenoic Acid; Kinetics; Linoleic Acid; Lipid Peroxidation; Oxidants; Oxidation-Reduction; Oxidative Stress; Saccharomyces cerevisiae; Ubiquinone | 2012 |
Kinetic investigation of the rate-limiting step of manganese- and iron-lipoxygenases.
Topics: alpha-Linolenic Acid; Arachidonate 15-Lipoxygenase; Biocatalysis; Deuterium; Fatty Acids, Unsaturated; Glycine max; Humans; Iron; Kinetics; Linoleic Acid; Lipoxygenase; Manganese; Mutation; Plant Proteins; Recombinant Proteins; Temperature; Thermodynamics | 2014 |
Metabolic conversion of intra-amniotically-injected deuterium-labeled essential fatty acids by fetal rats following maternal n-3 fatty acid deficiency.
Topics: alpha-Linolenic Acid; Amnion; Animals; Arachidonic Acid; Brain; Deuterium; Fatty Acids, Essential; Fatty Acids, Omega-3; Female; Fetus; Injections; Linoleic Acid; Liver; Pregnancy; Rats; Rats, Sprague-Dawley | 2014 |
Active Site Dynamical Effects in the Hydrogen Transfer Rate-limiting Step in the Catalysis of Linoleic Acid by Soybean Lipoxygenase-1 (SLO-1): Primary and Secondary Isotope Contributions.
Topics: Biocatalysis; Deuterium; Glycine max; Hydrogen; Hydrogen Bonding; Kinetics; Linoleic Acid; Lipoxygenase; Molecular Dynamics Simulation; Oxidation-Reduction; Protein Conformation; Quantum Theory; Thermodynamics; Vibration | 2015 |
A Revised Mechanism for Human Cyclooxygenase-2.
Topics: Arachidonic Acid; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Deuterium; Humans; Kinetics; Linoleic Acid; Mass Spectrometry; Mutant Proteins; Oxidation-Reduction; Oxygen Consumption; Solvents; Temperature; Viscosity | 2016 |
Mechanisms of lipid mobilization towards egg formation in broiler breeder hens using stable isotopes.
Topics: Age Factors; Animals; Carbon Isotopes; Chickens; Deuterium; Egg Yolk; Female; Gas Chromatography-Mass Spectrometry; Linoleic Acid; Lipid Mobilization; Ovum | 2017 |
Lipidomics Reveals Dramatic Physiological Kinetic Isotope Effects during the Enzymatic Oxygenation of Polyunsaturated Fatty Acids Ex Vivo.
Topics: Arachidonic Acid; Deuterium; Glycine max; Kinetics; Linoleic Acid; Lipids; Lipoxygenase; Molecular Structure; Oxygen; Prostaglandin-Endoperoxide Synthases | 2018 |
Deuterium-reinforced linoleic acid lowers lipid peroxidation and mitigates cognitive impairment in the Q140 knock in mouse model of Huntington's disease.
Topics: Animals; Body Weight; Cognitive Dysfunction; Deuterium; Dietary Supplements; Disease Models, Animal; Fatty Acids, Unsaturated; Female; Huntingtin Protein; Huntington Disease; Linoleic Acid; Lipid Peroxidation; Male; Mice, Transgenic; Motor Activity | 2018 |
Relative quantification of deuterated omega-3 and -6 fatty acids and their lipid turnover in PC12 cell membranes using TOF-SIMS.
Topics: alpha-Linolenic Acid; Animals; Cell Membrane; Deuterium; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Linoleic Acid; PC12 Cells; Phosphatidylinositols; Phospholipids; Rats | 2018 |
Isotope-reinforced polyunsaturated fatty acids improve Parkinson's disease-like phenotype in rats overexpressing α-synuclein.
Topics: alpha-Linolenic Acid; alpha-Synuclein; Animals; Axonal Transport; Behavior, Animal; Brain; Deuterium; Dopaminergic Neurons; Exploratory Behavior; Humans; Inflammation; Linoleic Acid; Mitochondria; Oxidative Stress; Parkinson Disease; Postural Balance; Rats; Rats, Transgenic; Substantia Nigra | 2020 |
The Protective Mechanism of Deuterated Linoleic Acid Involves the Activation of the Ca
Topics: Animals; Astrocytes; Calcium Signaling; Cell Survival; Cells, Cultured; Cytosol; Deuterium; Gene Expression Regulation; Hypoxia-Ischemia, Brain; Linoleic Acid; Mice; Models, Biological; Reactive Oxygen Species | 2021 |
Controlled Tetradeuteration of Straight-Chain Fatty Acids: Synthesis, Application, and Insight into the Metabolism of Oxidized Linoleic Acid.
Topics: Chromatography, Liquid; Deuterium; Fatty Acids; Linoleic Acid; Linoleic Acids; Tandem Mass Spectrometry | 2022 |