deuterium has been researched along with leucine in 183 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 57 (31.15) | 18.7374 |
| 1990's | 49 (26.78) | 18.2507 |
| 2000's | 55 (30.05) | 29.6817 |
| 2010's | 20 (10.93) | 24.3611 |
| 2020's | 2 (1.09) | 2.80 |
| Authors | Studies |
|---|---|
| Kearns, DR; Rordorf, BF | 1 |
| Dawson, RM; Freinkel, N; Younsi, CE | 1 |
| Gibbons, WA; Sogn, JA; Wolff, S | 1 |
| Cromartie, TH; Walsh, C | 1 |
| Dvoráková, M; Kotyk, A | 1 |
| Hoerr, RA; Marks, L; Pelletier, V; Wagner, DA; Young, VR | 1 |
| Burke, JF; Jaksic, T; Wagner, DA; Young, VR | 1 |
| Cuénod, M; Perschak, H | 1 |
| Bier, DM; Hoerr, RA; Matthews, DE; Young, VR | 2 |
| Cohn, JS; Cohn, SD; Millar, JS; Schaefer, EJ; Wagner, DA | 1 |
| Cohn, JS; Hachey, DL; Lichtenstein, AH; Millar, JS; Ordovas, JM; Schaefer, EJ | 1 |
| Halliday, D; Leonard, JV; Thompson, GN; Walter, JH | 1 |
| Burke, JF; Crowe, PJ; Royle, GT; Wagner, D | 1 |
| Lim, VS; Tsalikian, E | 1 |
| Floss, HG; Otsuka, H | 1 |
| Birdsall, B; Feeney, J; Griffiths, DV; Hammond, SJ; King, RW; Roberts, GC; Searle, MS | 1 |
| Andersson, L; MacNeela, J; Wolfenden, R | 1 |
| Haymond, MW; Nissen, SL; Schwenk, WF; Tessari, P; Tsalikian, E | 1 |
| Nishikimi, M; Oishi, N; Takai, A; Yagi, K | 1 |
| Damerau, W; Lassmann, G | 1 |
| Alms, H; Bockman, RS; Gibbons, WA; Wyssbrod, HR | 1 |
| Deslauriers, R; Smith, IC; Walter, R | 1 |
| Parker, FS; Stryker, MH | 1 |
| Hemmaplardh, D; Kailis, SG; Morgan, EH | 1 |
| Charache, S; Ho, C; Wiechelman, KJ | 1 |
| Kaplan, S; Kosakowski, MH | 1 |
| Hager, DL; Malaisse, WJ; Orci, L | 1 |
| Bukald, NE; Hirshfield, IN | 1 |
| Bonnar, J; Dawson, RM; Freinkel, N; Younsi, CE | 1 |
| Christensen, HN; Quay, S | 1 |
| Bonnar, J; Dawson, RM; el Younsi, C; Freinkel, N | 1 |
| Blake, MI; Kluza, RB; Rhodes, HJ | 1 |
| Baerlocher, K; Curtius, HC; Völlmin, JA | 1 |
| Glasel, JA; Hruby, VJ; McKelvy, JF; Spatola, AF | 1 |
| Bradbury, AF; Burgen, AS; Feeney, J; Roberts, GC; Smyth, DG | 1 |
| Nakada, D; Young, RM | 1 |
| Brisson, GR; Malaisse, WJ; Malaisse-Lagae, F | 1 |
| Feder, J; Schuck, JM | 1 |
| Glickson, JD; Mayers, DF; Settine, JM; Urry, DW | 1 |
| Gallop, PM; Mechanic, G; Tanzer, ML | 1 |
| Adams, MH; Midthun, RA; Rowley, PT | 1 |
| Brewer, HB; Bronzert, TJ; Fales, HM; Milne, GW; Nagai, Y; Pisano, JJ | 1 |
| Fisher, JM; Freedman, ML; Maxwell, CR; Rabinovitz, M | 1 |
| Go, A; Kopple, KD; Ohnishi, M | 1 |
| Crespi, HL; Daboll, HF; Katz, JJ | 1 |
| Siemion, IZ; Sucharda-Sobczyk, A | 1 |
| Blake, MI; Mohammed, K; Nona, DA | 1 |
| Abdullaev, ND; Bystrov, VF; Efremov, ES; Ivanov, VT; Miroshnikov, AI; Ovchinnikov, YA; Senyavina, LB; Shepel, EN | 1 |
| Cohen, JS; Putter, I; Smith, JL; Vandenheuvel, WJ | 1 |
| Dugas, H; Kaplan, H; Symonds, VB; Whitaker, DR | 1 |
| MacDonald, JC | 1 |
| Bessman, SP; Hammel-Dupont, CL | 1 |
| Brachet, J; Van Assel, S | 1 |
| Crespi, HL; Katz, JJ; Rosenberg, RM | 1 |
| Page, DS; VanEtten, RL | 1 |
| Aubin, A; Bellemare, G; Cousineau, GH; Daigneault, R; Pinard, J | 1 |
| Auer, HE; Doty, P | 1 |
| Jenkins, WT; Saier, MH | 1 |
| Gerich, JE; Haymond, MW; Miles, JM; Nissen, SL | 1 |
| Gerich, JE; Haymond, MW; Howard, C; Tsalikian, E | 1 |
| Batchelder, LS; Jelinski, LW; Sullivan, CE; Torchia, DA | 1 |
| Biemann, K; Herlihy, WC; Kidwell, D; Meeusen, B | 1 |
| Gerich, JE; Haymond, MW; Howard, CP; Miles, JM | 1 |
| Asakawa, N; Hashimoto, M; Ishibashi, M; Koyama, M; Miyazaki, H | 1 |
| Fong, Y; He, W; Lowry, SF; Marano, MA; Matthews, DE; Moldawer, LL | 1 |
| Biolo, G; Inchiostro, S; Tessari, P; Tiengo, A | 1 |
| Burrin, DG; Frazer, M; Jahoor, F; Reeds, PJ | 1 |
| Burke, JF; Chapman, TE; Vogt, JA; Wagner, DA; Young, VR | 1 |
| Ajami, A; Burke, JF; Castillo, L; Chapman, TE; Young, VR; Yu, YM | 1 |
| Ajami, A; Branch, S; Burke, JF; Castillo, L; Chapman, TE; Young, VR; Yu, YM | 1 |
| Ajami, AM; Burke, JF; Castillo, L; Chapman, TE; Sanchez, M; Vogt, J; Young, VR; Yu, YM | 1 |
| Fuller, JC; Huiatt, TW; Nissen, SL | 1 |
| Burke, JF; Castillo, L; Chapman, TE; deRojas, TC; Tannenbaum, SR; Vogt, J; Young, VR | 1 |
| Gleason, R; Hoerr, RA; Krempf, M; Marks, LM; Pelletier, VA; Young, VR | 1 |
| Kahler, SG; Millington, DS; Nada, MA; Rutledge, SL; van Hove, JL | 1 |
| Basile Filho, A; Beaumier, L; Castillo, L; Chapman, TE; El-Khoury, AE; Sanchez, M; Young, VR | 1 |
| Chapman, T; Maroni, BJ; Masud, T; Tom, K; Young, VR | 1 |
| Bedford, D; Bedynek, A; Demant, T; Demmelmair, H; Packard, CJ; Seidel, D; Shepherd, J; Stewart, P | 1 |
| Schaefer, JR; Schweer, H; Seyberth, HW; Steinmetz, A; Watzer, B | 1 |
| Shortle, D; Wang, Y | 1 |
| Bergmann, S; Gehrisch, S; Hanefeld, M; Jaross, W; Julius, U; Leonhardt, W; Nitzsche, S; Pietzsch, J; Wiedemann, B | 1 |
| Bartlett, K; Brock, C; Craft, AW; Daley, SE; Halliday, D; Hetherington, C; Kernahan, J; Pearson, AD; Price, L; Wyllie, RA | 1 |
| Auestad, N; Darmaun, D; Neu, J; Roig, JC; Sager, BK | 1 |
| Bedford, D; Caslake, M; Malmström, R; Packard, CJ; Shepherd, J; Stewart, P; Taskinen, MR; Yki-Järvinen, H | 1 |
| Anderson, SE; Calder, AG; Connell, A; Lobley, GE | 1 |
| Manatunga, A; Maroni, BJ; Staffeld, C; Tom, K; Young, VR | 1 |
| Frénais, R; Krempf, M; Magot, T; Mahot, P; Maugeais, C; Maugère, P; Ouguerram, K | 1 |
| Hamadeh, MJ; Hoffer, LJ; Mamer, OA; Robitaille, L; Taveroff, A | 1 |
| Barrett, PH; Dolnikowski, GG; Lichtenstein, AH; Ordovas, JM; Schaefer, EJ; Welty, FK | 1 |
| Darmaun, D; Hankard, RG; Haymond, MW | 1 |
| Schäfer, R | 1 |
| Ballmer, PE | 1 |
| Beaufrère, B; Boirie, Y; Bouteloup-Demange, C; Déchelotte, P; Gachon, P | 1 |
| Batal, R; Cohn, JS; Davignon, J; Genest, J; Krimbou, L; Mamer, O; Tremblay, M | 1 |
| Klein, S; Patterson, BW; Zhao, G | 1 |
| Forrester, T; Jahoor, F; Morlese, JF | 1 |
| Anderson, VE; Goshe, MB | 1 |
| Barazzoni, R; Tessari, P; Tiengo, A; Zanetti, M | 1 |
| Doyle, D; Ferrando, AA; Phillips, SM; Tipton, KD; Wolfe, RR | 1 |
| Denne, SC; Horswill, CA; Kien, CL; McCoy, KS; Zipf, WB | 1 |
| Gardner, KH; Goto, NK; Kay, LE; Mueller, GA; Willis, RC | 1 |
| Pereira, P; Raguso, CA; Young, VR | 1 |
| Elias, N; Patterson, BW; Schonfeld, G | 2 |
| Barrett, PH; Dolnikowski, GG; Lichtenstein, AH; Schaefer, EJ; Welty, FK | 1 |
| Anderson, VE; Chen, YH; Goshe, MB | 1 |
| Andersen, OS; Greathouse, DV; Hatchett, J; Jude, AR; Koeppe, RE; Providence, LL | 1 |
| Antoine, JM; Arnal, M; Arnal, MA; Bayle, G; Beaufrère, B; Boirie, Y; Gachon, P; Genest, M; Grizard, J; Mirand, PP; Mosoni, L | 1 |
| Abramson, FP; Lecchi, P | 1 |
| Atkinson, A; Bequette, BJ; El-Khoury, AE; Metges, CC; Regan, MM; Selvaraj, AB; Tsay, RH; Young, VR | 1 |
| Collin, S; Perpète, P | 1 |
| Hasegawa, H; Hashimoto, T; Matsukawa, T; Shinohara, Y | 1 |
| Herndon, DN; Jeschke, MG; Volpi, E; Wolfe, RR | 1 |
| Barrett, PH; Demant, T; Parhofer, KG; Schwandt, P | 1 |
| Lee, CH; Taylor, R; Whittaker, PG | 1 |
| Beaumier, L; Castillo, L; Lu, XM; Ryan, CM; Tompkins, RG; Young, VR; Yu, YM | 1 |
| Dolnikowski, GG; Lichtenstein, AH; Millar, JS; Ordovas, JM; Schaefer, EJ | 1 |
| Angeletti, RH; Grubmeyer, C; Nieves, E; Schramm, VL; Shi, W; Wang, F | 1 |
| Kainosho, M; Kobayashi, M; Nishiyama, K; Oba, M; Oikawa, F | 1 |
| Lario, PI; Sampson, NS; Vrielink, A; Yin, Y | 1 |
| Darmaun, D; Krempf, M; Magot, T; Maugeais, C; Maugère, P; Ouguerram, K | 1 |
| Devapatla, S; Gruca, L; Hanson, RW; Kalhan, SC; O'Brien, AM; Parimi, PS | 1 |
| Beynon, RJ; Butler, P; Gaskell, SJ; Hayes, A; Hubbard, SJ; Oliver, SG; Petty, J; Pratt, JM; Riba-Garcia, I; Robertson, DH; Sidhu, K | 1 |
| Barrett, PH; Chan, D; Croft, KD; Dwyer, KP; Foo, JI; Watts, GF | 1 |
| Bacher, A; Eisenreich, W; Goese, M; Kupfer, E; Schuhr, CA; Stohler, P; Weber, W | 1 |
| Ammatuna, M; Battezzati, A; Caumo, A; Coppa, J; Fattorini, A; Luzi, L; Mazzaferro, V; Regalia, E; Romito, R; Sereni, LP | 1 |
| Blagoev, B; Kratchmarova, I; Kristensen, DB; Mann, M; Ong, SE; Pandey, A; Steen, H | 1 |
| Badaloo, A; Forrester, T; Heird, WC; Jahoor, F; Reid, M | 2 |
| Børsheim, E; Tipton, KD; Wolf, SE; Wolfe, RR | 1 |
| Caldwell, K; Hellerstein, M; Neese, RA; Papageorgopoulos, C; Schweingrubber, H; Shackleton, CH | 1 |
| Gnanou, J; Kurpad, AV; Raj, T; Regan, MM; Thankachan, P; Varalakshmi, S; Young, VR | 1 |
| Claeyssens, S; Coëffier, M; Déchelotte, P; Ducrotté, P; Hecketsweiler, B; Lavoinne, A | 1 |
| Babraj, JA; Berré, J; Boisseau, N; Brassine, E; Cuthbertson, DJ; Francaux, M; Louis, M; Poortmans, JR; Rennie, MJ; Smith, K; Waddell, T | 1 |
| ORGEL, LE | 1 |
| Dante, S; Dencher, NA; Hauss, T | 1 |
| Brüschweiler, R; Zhang, F | 1 |
| Che, FY; Fricker, LD; Kalinina, E; Yuan, Q | 1 |
| Bourreille, A; Darmaun, D; Galmiche, JP; Humbert, B; Maugère, P | 1 |
| Adiels, M; Borén, J; Caslake, MJ; Olofsson, SO; Packard, C; Soro, A; Stewart, P; Taskinen, MR; Wennberg, B; Westerbacka, J | 2 |
| Damodaran, K; Dave, PC; Karp, ES; Lorigan, GA; Tiburu, EK | 1 |
| Aisenbrey, C; Bechinger, B | 1 |
| Barrett, PH; deLuca, C; Dolnikowski, GG; Jenner, JL; Lamon-Fava, S; Lichtenstein, AH; Marcovina, SM; Millar, JS; Schaefer, EJ; Seman, LJ; Welty, FK | 1 |
| Barrett, HR; Dolnikowski, GG; Jalbert, SM; Lamon-Fava, S; Lichtenstein, AH; Matthan, NR; Schaefer, EJ; Welty, FK | 1 |
| Clore, GM; Iwahara, J; Tang, C | 1 |
| Chen, Z; Hologne, M; Reif, B | 1 |
| Kay, LE; Tugarinov, V | 1 |
| Bilan, PJ; Foster, LJ; Furtado, LM; Huang, X; Klip, A; Mann, M; Patel, N; Rudich, A; Talior, I | 1 |
| Endoh, S; Yamauchi, N | 1 |
| English, AM; Jiang, H | 1 |
| Archer, WR; Bergeron, N; Couture, P; Deshaies, Y; Desroches, S; Lamarche, B; Paradis, ME; Ruel, IL | 1 |
| Chen, X; Gu, S; Liang, S; Xue, Y; Yang, P; Yu, Y | 1 |
| Gong, F; Liang, S; Liu, Q; Shen, G; Tang, M; Wei, Y; Xu, X; Xu, Y; Xu, Z | 1 |
| Baiocchi, MR; Coracina, A; Kiwanuka, E; Millioni, R; Puricelli, L; Semplicini, A; Tessari, P; Vettore, M; Zaramella, M | 1 |
| Bandaria, JN; Cheatum, CM; Cremeens, ME; Gundogdu, K; Hwang, GT; Romesberg, FE; Thielges, MC; Zimmermann, J | 1 |
| Corcelli, SA; Miller, CS | 1 |
| Boirie, Y; de Roos, AL; Fauquant, J; Gijsen, AP; Kies, AK; Koopman, R; Lemosquet, S; Saris, WH; van Loon, LJ | 1 |
| Breen, NF; Castner, DG; Drobny, GP; Li, K; Weidner, T | 1 |
| Burton, SD; Ford, JJ; Hoatson, GL; Lipton, AS; Ostrovsky, D; Vold, RL; Vugmeyster, L | 1 |
| Baldini, L; Casnati, A; Kalenius, E; Neitola, R; Sansone, F; Torvinen, M; Ungaro, R; Vainiotalo, P | 1 |
| Kay, LE; Religa, TL | 1 |
| Atreya, HS; D'Silva, P; Jaipuria, G; Thakur, A | 1 |
| Kay, LE; Ruschak, AM; Velyvis, A | 1 |
| Coats, B; Gregory, JF; Lamers, Y; Quinlivan, EP; Ralat, M; Stacpoole, PW | 1 |
| Gräslund, A; Madani, F; Mäler, L; Unnerståle, S | 1 |
| Dieplinger, B; Dieplinger, H; Frischmann, ME; Ikewaki, K; König, P; Kronenberg, F; Lamina, C; Schaefer, JR; Schweer, H; Soufi, M; Trenkwalder, E | 1 |
| Bôle-Feysot, C; Cailleux, AF; Claeyssens, S; Coëffier, M; Déchelotte, P; Donnadieu, N; Guérin, C; Lavoinne, A; Lecleire, S; Maurer, B | 1 |
| East, K; Hammel, SC; Rose, MR; Shahrestani, P; Shaka, AJ | 1 |
| Miyazawa-Onami, M; Shimada, I; Sugiki, T; Takahashi, H; Takano, T; Takeuchi, K | 1 |
| Basisty, N; Beyer, RP; Chen, T; Chiao, YA; Crispin, D; Dai, DF; Djukovic, D; Gu, H; Hsieh, EJ; Karunadharma, PP; MacCoss, MJ; Rabinovitch, PS; Raftery, D | 1 |
| Anthanont, P; Asztalos, BF; Barrett, PH; Billheimer, J; Cuchel, M; Diffenderfer, MR; Millar, JS; Polisecki, E; Rader, DJ; Schaefer, EJ | 1 |
| Basisty, N; Beyer, RP; Bielas, JH; Chiao, YA; Crispin, D; Dai, DF; Ericson, NG; Hsieh, EJ; Karunadharma, PP; MacCoss, MJ; MacKay, VL; Quarles, EK; Rabinovitch, PS | 1 |
| Frost, DC; Greer, T; Li, L; Liang, Z; Xiang, F | 1 |
| Liu, L; Lorigan, GA; McCarrick, RM; Sahu, ID | 1 |
| Akabayov, SR; Anglister, J; Arshava, B; Kessler, N; Moseri, A; Naider, F; Srivastava, G | 1 |
| Burd, NA; Franssen, R; Gijsen, AP; Gorissen, SH; Senden, JM; Snijders, T; van Loon, LJ; Wall, BT | 1 |
| Emery, MG; Gibbs, JP; Rock, BM; Rock, DA; Xie, F | 1 |
| Tanoue, R; Yamauchi, N | 1 |
| Koch, B; Mamone, S; Reif, B; Sarkar, R; Xue, K | 1 |
| Boon-Spijker, M; Ebberink, EHTM; Freato, N; Meijer, AB; Przeradzka, MA; van den Biggelaar, M; van der Zwaan, C; van Galen, J | 1 |
| Abdelkader, EH; Adekanmi, AJ; Adeyinka, AO; Afkari, BF; Agarwal, A; Aggelopoulos, S; Ai, G; Akiyama, T; Alcalde, MP; Aljohani, AI; Almeida, SCG; Alrefai-Kirkpatrick, R; Amri, M; An, S; Andreo, JC; Angelidi, AM; Anjos, D; Araujo, AC; Arena, A; Arif, MS; Bai, C; Bai, D; Ball, GR; Banerjee, BD; Barraviera, B; Becker, ME; Berdagué, P; Biswas, NR; Blair, RV; Borges, MASB; Brownell, EA; Buchaim, DV; Buchaim, RL; Bueno, CRS; Butler, EL; Buxó, M; Cao, Y; Carias, AM; Carson, TL; Casabona, J; Caterino-de-Araujo, A; Chang, HW; Chaudhary, E; Chauhan, K; Chen, C; Chen, F; Chen, J; Chen, K; Chen, LN; Chen, Q; Chen, Y; Chin, C; Cho, H; Christidis, P; Cleveland, LM; Colombo, D; Comolatti, R; Conti, F; Cook, AC; Coward, K; Crawford, AD; Cui, H; Cuyàs, E; da Fonseca, SG; Dadashi, M; Danish, S; Deng, C; Deorari, AK; Desai, R; Detregiachi, CRP; Devlin, AM; Dhanoya, T; Di Carlo, M; Díaz, Y; Ding, ZJ; Dong, S; Doyle, M; Doyle-Meyers, LA; Du, X; Duarte, MAH; El-Sharawy, KA; Engelward, BP; Espinoza, I; Fabre, A; Faggioli, P; Faisaluddin, M; Fan, CL; Ferreira, RS; Fiaccadori, FS; Fiocchi, M; Fong, HK; Foti, R; Franco, FC; Frassi, M; Fujimori, A; Fukasawa, LO; Fusaro, E; Ganesh, D; Gao, F; Gaur, A; Geetha, J; Geng, D; Geng, S; Gonçalves, MG; Gouilleux, B; Green, AR; Greiver, M; Grembiale, RD; Guggino, G; Guilarde, AO; Gupta, YK; Hafner, SM; He, H; He, YX; Henderson, AM; Herath, ID; Hirakawa, H; Hirota, S; Holzman, C; Hope, TJ; Hu, K; Huang, B; Huang, F; Huang, L; Huang, PY; Hultquist, JF; Iannone, F; Immel, S; Ioannidis, O; Jakiemiec, BE; Jia, X; Jiang, D; Jin, H; Jindal, S; Jones, C; Juel, BE; Kashir, J; Kawazu, R; Khodulev, VI; Kleer, CG; Kotidis, E; Kumar, G; Kumar, S; Kuninobu, Y; Kurapaty, C; Lee, MJ; Lei, ZY; Lemos, APS; Lesot, P; Li, M; Li, S; Li, W; Li, X; Li, Y; Liang, Y; Liao, YC; Limonta, M; Liu, C; Liu, JS; Liu, Q; Liu, X; Lomater, C; Lorenzo-Redondo, R; Loutzidou, L; Luo, L; Luo, X; Lupu, R; Ma, G; Ma, Q; Madden, PJ; Maleckis, A; Mancini, J; Mansoori, K; Mantzoros, I; Marchesoni, A; Margerison, CE; Mariano, GP; Mariorakis, C; Martinelli, E; Martinou, EG; Masuzawa, T; McGlothen-Bell, K; McGrath, JM; McRaven, MD; Medico, PD; Menendez, JA; Midkiff, CC; Miro, JM; Mirza, S; Moller-Levet, CS; Mondelli, B; Morgan, KM; Morhason-Bello, IO; Morse, AL; Morton, K; Moslemkhani, C; Mukherjee, M; Namvar, MA; Nelson, RK; Nenoi, M; Ngai, YF; Nickoloff, JA; Nishida, T; Noll, M; Nomah, DK; Orsenigo, R; Otting, G; Ouzounidis, N; Pan, L; Panagiotopoulos, C; Park, CH; Patel, S; Patel, U; Perricone, R; Pomini, KT; Ponomarev, VV; Pramateftakis, MG; Prasad, P; Puttini, PCS; Quan, JY; Rademaker, A; Raffeiner, B; Rakha, EA; Recto, P; Reggelin, M; Reis, CHB; Ren, B; Reyes-Urueña, J; Reynolds, C; Ribeiro, BM; Rizzoli, S; Roberts, A; Roncari, B; Sacchi, CT; Sachdeva, R; Sai, S; Saikia, D; Sakthivadivel, V; Saltarelli, WA; Samer, S; Sangam, S; Scott, L; Servian, CDP; Shang, X; Shi, LZ; Shih, IA; Simons, LM; Singh, RP; Singh, S; Souza, M; Stepanova, JI; Sterner, NJ; Storm, JF; Su, X; Suzuki, M; Takahashi, T; Talge, NM; Tang, X; Teixeira, DB; Thomas, Y; Thon, S; Tian, CY; Tipre, M; Tirri, E; Torigoe, T; Toss, MS; Tripathi, A; Tsalis, K; Tworek, C; Vander Steen, T; Veazey, RS; Velpandian, T; Venugopal, PD; Verdura, S; Viapiana, O; Villinger, FJ; Vita, S; Vivanco-Hidalgo, RM; Walker, WJ; Wang, B; Wang, C; Wang, H; Wang, J; Wang, L; Wang, S; Wang, X; Wang, Y; Wei, L; Wen, Y; Wiedeman, AM; Wiley, E; Wintemute, K; Wu, C; Wu, J; Wu, S; Wu, W; Xiang, W; Xiao, S; Xiong, W; Xiong, Z; Xu, J; Xu, NS; Yang, J; Yang, Z; Ye, L; Ye, WC; You, HL; Yu, LZ; Zagni, E; Zamani-Hank, Y; Zhan, S; Zhang, J; Zhang, L; Zhang, X; Zhang, Y; Zhang, Z; Zhao, K; Zhao, L; Zhao, Z; Zheng, J; Zheng, X; Zheng, YR; Zhou, J; Zhu, M; Zhu, Q; Zou, C; Zou, S | 1 |
1 review(s) available for deuterium and leucine
16 trial(s) available for deuterium and leucine
| Article | Year |
|---|---|
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: valine metabolism at different leucine intakes.
Topics: Adult; Carbon Isotopes; Deuterium; Fasting; Food; Humans; Infusions, Intravenous; Isoleucine; Kinetics; Leucine; Male; Nutritional Requirements; Oxidation-Reduction; Valine | 1991 |
How is lean body mass conserved with the very-low protein diet regimen?
Topics: Adult; Aged; Amino Acids, Essential; Body Weight; Carbon Isotopes; Cross-Over Studies; Deuterium; Diet, Protein-Restricted; Energy Intake; Female; Food, Fortified; Humans; Isotope Labeling; Keto Acids; Kidney Failure, Chronic; Leucine; Male; Middle Aged; Nitrogen; Proteins; Thinness | 1996 |
Glutamine metabolism in very low birth weight infants.
Topics: Carbon Isotopes; Case-Control Studies; Deuterium; Gestational Age; Glutamine; Humans; Infant Food; Infant, Newborn; Infant, Very Low Birth Weight; Leucine; Splanchnic Circulation | 1997 |
Postexercise net protein synthesis in human muscle from orally administered amino acids.
Topics: Administration, Oral; Adult; Amino Acids; Amino Acids, Essential; Deuterium; Female; Humans; Leucine; Lysine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Physical Exertion | 1999 |
A tracer investigation of obligatory oxidative amino acid losses in healthy, young adults.
Topics: Adult; Amino Acids, Essential; Carbon Dioxide; Carbon Isotopes; Deuterium; Diet, Protein-Restricted; Gas Chromatography-Mass Spectrometry; Humans; Keto Acids; Leucine; Methionine; Nitrogen Isotopes; Oxidation-Reduction; Urea | 1999 |
Decreased production rates of VLDL triglycerides and ApoB-100 in subjects heterozygous for familial hypobetalipoproteinemia.
Topics: Adolescent; Adult; Aged; Apolipoprotein B-100; Apolipoproteins B; Cholesterol, VLDL; Deuterium; Family Health; Fatty Acids, Nonesterified; Female; Heterozygote; Humans; Hypobetalipoproteinemias; Kinetics; Leucine; Male; Middle Aged; Palmitic Acid; Point Mutation; Triglycerides | 1999 |
Human apolipoprotein (Apo) B-48 and ApoB-100 kinetics with stable isotopes.
Topics: Aged; Apolipoprotein B-100; Apolipoprotein B-48; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Deuterium; Female; Humans; Kinetics; Leucine; Lipoproteins; Liver; Male; Middle Aged | 1999 |
Protein turnover modifications induced by the protein feeding pattern still persist after the end of the diets.
Topics: Adaptation, Physiological; Adult; Aged; Aging; Bicarbonates; Blood Glucose; Carbon Isotopes; Deuterium; Diet; Dietary Proteins; Energy Intake; Female; Food; Humans; Insulin; Kinetics; Leucine; Proteins | 2000 |
Arginine and ornithine kinetics in severely burned patients: increased rate of arginine disposal.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Burns; Carbon Isotopes; Deuterium; Female; Humans; Kinetics; Leucine; Male; Middle Aged; Nitrogen Isotopes; Ornithine; Oxidation-Reduction; Parenteral Nutrition, Total; Proline | 2001 |
Leucine requirement and splanchnic uptake of leucine in chronically undernourished adult Indian subjects.
Topics: Adult; Body Composition; Body Weight; Breath Tests; Calorimetry, Indirect; Carbon Isotopes; Chronic Disease; Deuterium; Diet; Dietary Carbohydrates; Dietary Fats; Edible Grain; Fasting; Food; Humans; India; Infusions, Intravenous; Lens Plant; Leucine; Male; Nutrition Disorders; Nutritional Requirements; Oxidation-Reduction; Splanchnic Circulation; Viscera | 2003 |
Enteral glutamine stimulates protein synthesis and decreases ubiquitin mRNA level in human gut mucosa.
Topics: Adult; Amino Acids; Calpain; Carbon Isotopes; Cathepsin D; Deuterium; Duodenum; Enteral Nutrition; Female; Gas Chromatography-Mass Spectrometry; Glutamine; Humans; Insulin; Intestinal Mucosa; Intubation, Gastrointestinal; Leucine; Male; Phenylalanine; Protein Biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ubiquitin | 2003 |
TRL, IDL, and LDL apolipoprotein B-100 and HDL apolipoprotein A-I kinetics as a function of age and menopausal status.
Topics: Adult; Age Factors; Aged; Aging; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Deuterium; Female; Humans; Leucine; Lipoproteins; Lipoproteins, HDL; Menopause; Middle Aged; Postmenopause; Triglycerides | 2005 |
Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia.
Topics: Adult; Apolipoproteins B; Blood Glucose; Cholesterol, HDL; Cholesterol, VLDL; Deuterium; Diabetes Mellitus, Type 2; Dyslipidemias; Glycerol; Humans; Hyperglycemia; Insulin Resistance; Leucine; Male; Triglycerides | 2005 |
Kinetics of plasma apolipoprotein C-III as a determinant of diet-induced changes in plasma triglyceride levels.
Topics: Adult; Apolipoprotein C-III; Deuterium; Diet, Fat-Restricted; Fatty Acids, Monounsaturated; Humans; Leucine; Liver; Male; Triglycerides | 2008 |
Moderate vitamin B-6 restriction does not alter postprandial methionine cycle rates of remethylation, transmethylation, and total transsulfuration but increases the fractional synthesis rate of cystathionine in healthy young men and women.
Topics: Adult; Breath Tests; Carbon Isotopes; Cystathionine; Deuterium; Diet; DNA Methylation; Female; Humans; Kinetics; Leucine; Male; Methionine; Methylation; Monocytes; Postprandial Period; Pyridoxal Phosphate; Reproducibility of Results; Severity of Illness Index; Vitamin B 6; Vitamin B 6 Deficiency; Young Adult | 2011 |
Enteral delivery of proteins stimulates protein synthesis in human duodenal mucosa in the fed state through a mammalian target of rapamycin-independent pathway.
Topics: Adult; Carbon Isotopes; Deuterium; Dietary Proteins; Duodenum; Enteral Nutrition; Extracellular Signal-Regulated MAP Kinases; Glutamine; Humans; Hyperinsulinism; Intestinal Mucosa; Leucine; Male; Phenylalanine; Phosphatidylinositol 3-Kinase; Phosphorylation; Postprandial Period; Protein Biosynthesis; Protein Processing, Post-Translational; TOR Serine-Threonine Kinases; Up-Regulation; Young Adult | 2013 |
166 other study(ies) available for deuterium and leucine
| Article | Year |
|---|---|
NMR investigation of proton exchange in transfer RNA by high resolution NMR.
Topics: Deuterium; Hydrogen-Ion Concentration; Leucine; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Phenylalanine; RNA, Transfer; Saccharomyces cerevisiae; Solvents; Temperature; Tritium; Water | 1975 |
Insulin release and phosphate ion efflux from rat pancreatic islets induced by L-leucine and its nonmetabolizable analogue, 2-aminobicyclo[2.2.1]heptane-2-carboxylic acid.
Topics: Amino Acids; Bridged Bicyclo Compounds; Deuterium; Dose-Response Relationship, Drug; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Mannoheptulose; Phosphates; Stereoisomerism | 1976 |
Synthesis and N.M.R. spectral analysis of leucine -dgamma.
Topics: 1-Propanol; Alkylation; Deuterium; Leucine; Magnetic Resonance Spectroscopy | 1976 |
Mechanistic studies on the rat kidney flavoenzyme L-alpha-hydroxy acid oxidase.
Topics: Alcohol Oxidoreductases; Animals; Deuterium; Dithiothreitol; Flavoproteins; Hydroxy Acids; Isomerism; Kidney; Kinetics; L-Lactate Dehydrogenase; Lactates; Leucine; Rabbits; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Time Factors | 1975 |
Are proton symports in yeast directly linked to H(+)-ATPase acidification?
Topics: Deuterium; Diethylstilbestrol; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Leucine; Lysine; Membrane Potentials; Proton-Translocating ATPases; Protons; Saccharomyces cerevisiae; Suloctidil | 1992 |
Proline metabolism in adult male burned patients and healthy control subjects.
Topics: Adult; Burns; Carbon Isotopes; Deuterium; Humans; Kinetics; Leucine; Male; Oxidation-Reduction; Proline | 1991 |
In vivo release of endogenous glutamate and aspartate in the rat striatum during stimulation of the cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Deuterium; Electric Stimulation; Glutamates; Glutamic Acid; Kinetics; Leucine; Male; Rats; Rats, Inbred Strains | 1990 |
Leucine kinetics from [2H3]- and [13C]leucine infused simultaneously by gut and vein.
Topics: Adult; Amino Acids; Carbon Isotopes; Deuterium; Humans; Infusions, Intravenous; Intestinal Absorption; Isotope Labeling; Keto Acids; Kinetics; Leucine; Male; Radioisotope Dilution Technique | 1991 |
Measurement of very low density and low density lipoprotein apolipoprotein (Apo) B-100 and high density lipoprotein Apo A-I production in human subjects using deuterated leucine. Effect of fasting and feeding.
Topics: Adult; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins A; Apolipoproteins B; Cholesterol; Deuterium; Fasting; Food; Humans; Leucine; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Triglycerides | 1990 |
Comparison of deuterated leucine, valine, and lysine in the measurement of human apolipoprotein A-I and B-100 kinetics.
Topics: Adult; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins A; Apolipoproteins B; Deuterium; Humans; Kinetics; Leucine; Lipoproteins; Lysine; Valine | 1990 |
In vivo enzyme activity in inborn errors of metabolism.
Topics: Adult; Bicarbonates; Carbon Isotopes; Child; Child, Preschool; Deuterium; Female; Humans; Hydroxylation; Isotope Labeling; Leucine; Male; Malonates; Maple Syrup Urine Disease; Metabolism, Inborn Errors; Methylmalonic Acid; Oxidation-Reduction; Phenylalanine; Phenylketonurias; Propionates; Radioisotope Dilution Technique; Reference Values; Tyrosine | 1990 |
Does hyperketonemia affect protein or glucose kinetics in postabsorptive or traumatized man?
Topics: Aged; Blood Glucose; C-Peptide; Carbon Isotopes; Deuterium; Female; Glucose; Hip Prosthesis; Humans; Hydroxybutyrates; Infusions, Intravenous; Insulin; Ketone Bodies; Kinetics; Leucine; Male; Middle Aged; Proteins; Wounds and Injuries | 1989 |
L-triiodothyronine at a slightly over physiologic dose increases leucine flux, which suggests an increase in protein degradation in normal subjects.
Topics: Adult; Alanine; Deuterium; Female; Humans; Kinetics; Leucine; Male; Middle Aged; Nitrogen; Nitrogen Isotopes; Thyrotropin; Thyroxine; Triiodothyronine | 1989 |
Steric course of the rhodium-catalyzed decarbonylation of chiral 4-methyl-[1-3H,2-2H1]pentanal.
Topics: Caproates; Chemical Phenomena; Chemistry; Deuterium; Leucine; Rhodium; Stereoisomerism; Tritium | 1987 |
Identification of the 1H resonances of valine and leucine residues in dihydrofolate reductase by using a combination of selective deuteration and two-dimensional correlation spectroscopy.
Topics: Deuterium; Lacticaseibacillus casei; Leucine; Magnetic Resonance Spectroscopy; Protein Binding; Tetrahydrofolate Dehydrogenase; Trimethoprim; Valine | 1986 |
Use of secondary isotope effects and varying pH to investigate the mode of binding of inhibitory amino aldehydes by leucine aminopeptidase.
Topics: Deuterium; Enzymes, Immobilized; Hydrogen-Ion Concentration; Kinetics; Leucine; Leucyl Aminopeptidase; Structure-Activity Relationship; Water | 1985 |
Effects of [15N]leucine infused at low rates on leucine metabolism in humans.
Topics: Breath Tests; Carbon Radioisotopes; Deuterium; Female; Humans; Keto Acids; Leucine; Male; Models, Biological; Nitrogen Isotopes; Oxidation-Reduction; Proteins; Tritium | 1985 |
Mechanism of enzyme action. VI. Kinetic isotope effect on D-amino acid oxidase reaction.
Topics: Alanine; Aminobutyrates; Anaerobiosis; D-Amino-Acid Oxidase; Deuterium; Isotope Labeling; Kinetics; Leucine; Macromolecular Substances; Mathematics; Oscillometry; Oxygen Consumption; Protein Binding; Spectrophotometry; Time Factors; Valine | 1973 |
[ESR studies on x-irradiated leucine salts. 3. Structure of radicals in irradiated single crystals of L-leucine, HBr and L-leucine,DBr].
Topics: Bromides; Crystallography; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Leucine; Radiation Effects; Radiochemistry; Stereoisomerism | 1969 |
Homonuclear indor spectroscopy as a means of simplifying and analyzing proton magnetic resonance spectra of peptides and as a basis for determining secondary and tertiary conformations of complex peptides.
Topics: Amino Acids; Deuterium; Leucine; Magnetic Resonance Spectroscopy; Methods; Nuclear Physics; Peptides; Polymyxins; Protein Conformation; Tyrothricin; Valine | 1972 |
The conformation of oxytocin in dimethylsulfoxide as revealed by carbon-13 spin-lattice relaxation times.
Topics: Carbon Isotopes; Computers; Deuterium; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Fourier Analysis; Glucosamine; Isoleucine; Leucine; Molecular Conformation; Oxytocin; Time Factors; Tyrosine | 1974 |
A hydrogen--deuterium exchange study of the conformation of bovine liver glutamate dehydrogenase.
Topics: Adenine Nucleotides; Animals; Cattle; Chemical Phenomena; Chemistry; Deuterium; Diethylstilbestrol; Glutamate Dehydrogenase; Glutamates; Guanine Nucleotides; Hydrogen; Infrared Rays; Leucine; Liver; Methionine; NAD; NADP; Spectrophotometry | 1970 |
The effects of inhibitors of microtubule and microfilament function on transferrin and iron uptake by rabbit reticulocytes and bone marrow.
Topics: Adenosine Triphosphate; Animals; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Cell Membrane; Citrates; Colchicine; Cytochalasin B; Cytoplasm; Deuterium; Glycine; In Vitro Techniques; Iron; Iron Radioisotopes; Leucine; Microscopy, Electron; Microtubules; Rabbits; Reticulocytes; Strychnine; Transferrin; Vinblastine; Vincristine | 1974 |
Nuclear magnetic resonance studies of hemoglobin Chesapeake: an alpha1beta2 mutant.
Topics: Arginine; Carbon Monoxide; Carboxyhemoglobin; Chromatography, Gel; Chromatography, Ion Exchange; Deuterium; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Kinetics; Leucine; Ligands; Magnetic Resonance Spectroscopy; Maryland; Mutation; Oxygen; Oxyhemoglobins; Protein Conformation; Ultrafiltration | 1974 |
Topology and growth of the intracytoplasmic membrane system of Rhodopseudomonas spheroides: protein, chlorophyll, and phospholipid insertion into steady-state anaerobic cells.
Topics: Acetates; Anaerobiosis; Bacterial Chromatophores; Bacterial Proteins; Carbon Radioisotopes; Centrifugation, Density Gradient; Chlorophyll; Culture Media; Deuterium; Leucine; Levulinic Acids; Microscopy, Electron; Models, Biological; Ornithine; Oxides; Phenylalanine; Phospholipids; Rhodobacter sphaeroides; Stereoisomerism; Tritium; Water | 1974 |
The stimulus-secretion coupling of glucose-induced insulin release. IX. The participation of the beta cell web.
Topics: Calcium; Deuterium; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Microscopy, Electron; Mycotoxins; Protein Biosynthesis; Stimulation, Chemical; Sulfonylurea Compounds; Theophylline | 1972 |
Effect of alanine, leucine and fructose on lysyl-transfer ribonucleic acid ligase activity in a mutant of Escherichia coli K-12.
Topics: Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Carbohydrate Metabolism; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Culture Media; Deuterium; Escherichia coli; Fructose; Glucose; Leucine; Lysine; Mutation; Stereoisomerism; Stimulation, Chemical | 1973 |
Rapid transient efflux of phosphate ions from pancreatic islets as an early action of insulin secretagogues.
Topics: Animals; Antigens; Calcium; Deuterium; Female; Fructose; Galactose; Glucose; In Vitro Techniques; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Mannose; Nickel; Oxides; Perfusion; Phosphates; Phosphorus Radioisotopes; Radioimmunoassay; Rats; Stimulation, Chemical; Time Factors | 1974 |
Basis of transport discrimination of arginine from other basic amino acids in Salmonella typhimurium.
Topics: Alanine; Amino Acids; Arginine; Autoanalysis; Biological Transport; Carbon Radioisotopes; Chromatography, Ion Exchange; Deuterium; Glucose; Histidine; Homoserine; Hydroxyproline; Kinetics; Leucine; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Ornithine; Proline; Salmonella typhimurium; Structure-Activity Relationship; Tritium; Tryptophan | 1974 |
The "phosphate flush": a new index of secretory stimulation in pancreatic islets.
Topics: Animals; Deuterium; Female; Glucose; Insulin; Insulin Secretion; Iontophoresis; Islets of Langerhans; Leucine; Perfusion; Phosphates; Rats; Stimulation, Chemical; Tetracaine | 1974 |
Deuterium isotope effect in enzymatic transamination of L-deuterio-phenylalanine to deuterio-phenylpyruvic acid.
Topics: Amination; Animals; Brain Chemistry; Cell Wall; Chromatography, Ion Exchange; Chromatography, Thin Layer; Deuterium; Eukaryota; Hydrolysis; Kinetics; Leucine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phenylalanine; Phenylpyruvic Acids; Rats; Spectrophotometry, Infrared; Spectrum Analysis; Time Factors | 1973 |
Study of metabolic pathways in vivo using stable isotopes.
Topics: Benzoates; Chromatography, Gas; Deuterium; Hippurates; Humans; Isotope Labeling; Leucine; Mass Spectrometry; Metabolism, Inborn Errors; Methods; Tyrosine | 1973 |
Deuteron magnetic resonance studies on the microdynamical behavior of partially deuterated oxytocin with neurophysin.
Topics: Chromatography, Gel; Chromatography, Thin Layer; Circular Dichroism; Deuterium; Electrophoresis, Polyacrylamide Gel; Glycine; Leucine; Magnetic Resonance Spectroscopy; Mathematics; Neurophysins; Oligopeptides; Oxytocin; Proline; Spectrophotometry, Ultraviolet | 1973 |
Unequivocal assignments of NH proton magnetic resonance bands in oxytocin using 2H- and 15N-substituted molecules.
Topics: Animals; Biological Assay; Chromatography, Gel; Chromatography, Thin Layer; Crystallization; Deuterium; Female; Isoleucine; Isotope Labeling; Leucine; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Oxytocin; Protein Conformation; Rats; Structure-Activity Relationship; Tyrosine; Uterus | 1974 |
Ribosomal protein pool of Escherichia coli.
Topics: Ammonium Chloride; Bacterial Proteins; Carbon Isotopes; Centrifugation, Density Gradient; Chloramphenicol; Chlorides; Culture Media; Deuterium; Electrophoresis; Escherichia coli; Leucine; Lysine; Nitrogen Isotopes; Ribosomes; RNA, Ribosomal; Rubidium; Time Factors; Tritium; Uracil | 1970 |
The stimulus-secretion coupling of glucose-induced insulin release. VI. Analogy between the insulinotropic mechanisms of sugars and amino acids.
Topics: Animals; Arginine; Calcium; Calcium Isotopes; Deuterium; Diazoxide; Drug Antagonism; Epinephrine; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Mannose; Microscopy, Electron; Microtubules; Rats; Stimulation, Chemical | 1971 |
Studies on the Bacillus subtilis neutral-protease- and Bacillus thermoproteolyticus thermolysin-catalyzed hydrolysis of dipeptide substrates.
Topics: Acrylates; Bacillus; Bacillus subtilis; Deuterium; Dipeptides; Furans; Hydrogen-Ion Concentration; Kinetics; Leucine; Peptide Hydrolases; Phenylalanine; Spectrophotometry | 1970 |
Spectroscopic studies on the conformation of gramicidin A'. Proton magnetic resonance assignments, coupling constants, and H-D exchange.
Topics: Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Hydrogenation; Kinetics; Leucine; Magnetic Resonance Spectroscopy; Protein Conformation; Protons; Tryptophan; Tyrothricin; Valine | 1972 |
The nature of crosslinking in collagens from mineralized tissues.
Topics: Aldehydes; Animals; Bone and Bones; Borohydrides; Cattle; Chromatography; Collagen; Dentin; Deuterium; Fetus; In Vitro Techniques; Leucine; Mass Spectrometry; Oxidation-Reduction; Schiff Bases; Tritium | 1971 |
Solubilization of a reticulocyte ribosomal fraction responsible for the decline in ribosomal activity with cell maturation.
Topics: Aging; Animals; Blood Proteins; Carbon Isotopes; Cattle; Centrifugation, Density Gradient; Chlorides; Deuterium; Electrophoresis; Hemoglobins; Leucine; Magnesium; Phenylalanine; Polynucleotides; Potassium Chloride; Reticulocytes; Ribonucleases; Ribosomes; RNA, Messenger; RNA, Viral; Serum Albumin, Bovine; Solubility; Spectrophotometry; Time Factors; Tritium; Ultraviolet Rays; Uracil Nucleotides | 1971 |
Use of chemical ionization mass spectrometry in analysis of amino acid phenylthiohydantoin derivatives formed during Edman degradation of proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Cetacea; Chromatography, Gas; Deuterium; Glutamine; Glycine; Hydantoins; Leucine; Mass Spectrometry; Methods; Myoglobin; Sulfides; Tryptophan; Valine | 1971 |
Translational control in hemoglobin syntheskis.
Topics: Animals; Blood Proteins; Cell-Free System; Depression, Chemical; Deuterium; Globins; Heme; Hemoglobins; Hemoglobins, Abnormal; Iron; Iron Isotopes; Isoleucine; Leucine; Liver; Metabolism; Models, Biological; Models, Structural; Peptide Biosynthesis; Porphyrins; Pyridines; Rabbits; Reticulocytes; Ribosomes; RNA, Bacterial; RNA, Neoplasm; RNA, Transfer; Spectrophotometry; Stimulation, Chemical; Temperature; Threonine; Ultraviolet Rays | 1969 |
Conformations of cyclic peptides. IV. Nuclear magnetic resonance studies of cyclo-pentaglycyl-L-leucyl and cyclo-diglycyl-L-histidyldiglycyl-L-tyrosyl.
Topics: Deuterium; Dimethyl Sulfoxide; Fluoroacetates; Glycine; Histidine; Hot Temperature; Leucine; Magnetic Resonance Spectroscopy; Peptides; Solvents; Tyrosine | 1969 |
The biosynthesis of isotope hybrid proteins for high resolution nuclear magnetic resonance studies by incorporation of [1H]amino acids into fully deuterated algae.
Topics: Alanine; Amino Acids; Deuterium; Eukaryota; Hydrogen; Leucine; Magnetic Resonance Spectroscopy; Methionine; Phenylalanine; Protein Biosynthesis; Tyrosine | 1970 |
On the conformation of dipeptides in aqueous solutions.
Topics: Bromides; Chemical Phenomena; Chemistry; Deuterium; Dipeptides; Glycine; Infrared Rays; Leucine; Magnetic Resonance Spectroscopy; Optical Rotatory Dispersion; Phenylalanine; Solutions; Spectrum Analysis; Stereoisomerism; Water | 1970 |
Effect of heavy water on three high producing strains of Penicillium chrysogenum.
Topics: Deuterium; Glucose; Hydrogen-Ion Concentration; Leucine; Penicillins; Penicillium; Phenylacetates | 1970 |
The conformation of gramicidin S and its N,N'-diacetyl derivative in solutions.
Topics: Acetates; Chloroform; Deuterium; Infrared Rays; Leucine; Magnetic Resonance Spectroscopy; Models, Structural; Optical Rotatory Dispersion; Ornithine; Phenylalanine; Solvents; Stereoisomerism; Tyrothricin; Valine | 1970 |
Gas-liquid chromatography and mass spectrometry of deuterium-containing amino acids as their trimethylsilyl derivatives.
Topics: Alanine; Amino Acids; Asparagine; Chromatography, Gas; Deuterium; Glycine; Leucine; Methionine; Proline; Silicon; Spectrum Analysis; Tyrosine; Valine | 1970 |
A comparison of properties of the alpha-lytic protease of Sorangium sp. and porcine elastase.
Topics: Alanine; Amino Acids; Animals; Deuterium; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Ketones; Kinetics; Leucine; Myxomycetes; Optical Rotatory Dispersion; Pancreatic Elastase; Peptide Hydrolases; Serine; Swine | 1970 |
Biosynthesis of compounds similar to aspergillic acid.
Topics: Amino Acids; Aspergillus; Chromatography; Culture Media; Deuterium; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Methods; Pyrazines; Spectrum Analysis; Valine; Yeast, Dried | 1970 |
The stimulation of hemoglobin synthesis by porphyrins.
Topics: Animals; Carbon Isotopes; Cell Nucleus; Cobalt; Copper; Depression, Chemical; Deuterium; Drug Antagonism; Erythrocytes; Globins; Heme; Hemoglobins; Iron; Lead; Leucine; Mercury; Nickel; Organometallic Compounds; Porphyrins; Stimulation, Chemical; Tin | 1970 |
[The formation of cytasters and the metabolism of nucleic acids and proteins in amphibian eggs treated with heavy water].
Topics: Animals; Anura; Carbon Isotopes; Cycloheximide; Dactinomycin; Deuterium; DNA; Female; Hydroxyurea; Leucine; Mercaptoethanol; Nucleic Acids; Organoids; Ovum; Protein Biosynthesis; Puromycin; Radiation Effects; RNA; Urodela | 1968 |
Proton magnetic resonance of proteins fully deuterated except for 1H-leucine side chains.
Topics: Cytochromes; Deuterium; Eukaryota; Leucine; Magnetic Resonance Spectroscopy; Pigments, Biological; Protein Biosynthesis; Proteins | 1968 |
pH-dependent deuterium isotope effects on L-amino-acid oxidase.
Topics: Amino Acid Oxidoreductases; Binding Sites; Chemical Phenomena; Chemistry; Deuterium; Hydrogen-Ion Concentration; Kinetics; Leucine; Protons; Water | 1969 |
Uptake and incorporation of leucine and thymidine in developing sea urchin eggs. The effect of D2O.
Topics: Animals; Carbon Isotopes; Deuterium; DNA; Echinodermata; Female; Fertilization; Leucine; Ovum; Thymidine; Time Factors | 1969 |
The conformational stability of alpha-helical nonpolar polypeptides in solution.
Topics: Chemical Phenomena; Chemistry, Physical; Deuterium; Leucine; Peptides; Phenylalanine; Solutions; Thermodynamics | 1966 |
Alanine aminotransferase. II. The basis for substrate specificity.
Topics: Alanine; Alanine Transaminase; Amino Acids; Aminobutyrates; Animals; Chemical Phenomena; Chemistry; Deuterium; Formates; Glutamates; In Vitro Techniques; Kinetics; Leucine; Myocardium; Ornithine; Swine | 1967 |
Effects of epinephrine infusion on leucine and alanine kinetics in humans.
Topics: Adolescent; Adult; Alanine; Blood Glucose; Deuterium; Epinephrine; Gas Chromatography-Mass Spectrometry; Glucagon; Humans; Insulin; Kinetics; Leucine; Nitrogen Isotopes | 1984 |
Increased leucine flux in short-term fasted human subjects: evidence for increased proteolysis.
Topics: Adult; Deuterium; Fasting; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Leucine; Metabolic Clearance Rate; Nitrogen Isotopes; Proteins; Time Factors | 1984 |
Deuterium nuclear magnetic resonance of specifically labeled native collagen. Investigation of protein molecular dynamics using the quadrupolar echo technique.
Topics: Alanine; Animals; Bone and Bones; Chickens; Collagen; Deuterium; Leucine; Magnetic Resonance Spectroscopy; Mathematics; Models, Biological; Protein Conformation | 1980 |
Mass spectrometric differentiation of leucine and isoleucine in proteins derived from bacteria or cell culture.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Cells, Cultured; Deuterium; Gas Chromatography-Mass Spectrometry; Isoleucine; Leucine; Mass Spectrometry; Proteins | 1981 |
Determination of leucine flux in vivo by gas chromatography-mass spectrometry utilizing stable isotopes for trace and internal standard.
Topics: Animals; Deuterium; Dogs; Gas Chromatography-Mass Spectrometry; Infusions, Parenteral; Leucine | 1980 |
Simultaneous determination of bestatin and p-hydroxybestatin, a major metabolite, in human serum by gas chromatography mass spectrometry. Utilization of quantitative selected ion monitoring and deuterium labelled internal standard.
Topics: Adult; Deuterium; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Humans; Leucine; Middle Aged | 1980 |
Whole body and splanchnic leucine, phenylalanine, and glucose kinetics during endotoxemia in humans.
Topics: Acute-Phase Proteins; Adult; Blood Glucose; Carbon Isotopes; Deuterium; Endotoxins; Escherichia coli; Glucose; Humans; Isotope Labeling; Kinetics; Leucine; Male; Phenylalanine; Proteins; Splanchnic Circulation; Toxemia | 1994 |
Regulation of postprandial whole-body proteolysis in insulin-deprived IDDM.
Topics: Adult; Amino Acids; Blood Glucose; Deuterium; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Food; Food, Formulated; Humans; Hydrogen-Ion Concentration; Insulin; Kinetics; Leucine; Male; Middle Aged; Phenylalanine; Proteins | 1995 |
Measurement of plasma protein synthesis rate in infant pig: an investigation of alternative tracer approaches.
Topics: Alanine; Animals; Animals, Newborn; Apolipoprotein B-100; Apolipoproteins B; Blood Proteins; Carbon Isotopes; Deuterium; Female; Fibrinogen; Leucine; Liver; Lysine; Male; Serum Albumin; Swine | 1994 |
Determination of the isotope enrichment of one or a mixture of two stable labelled tracers of the same compound using the complete isotopomer distribution of an ion fragment; theory and application to in vivo human tracer studies.
Topics: Carbon Dioxide; Carbon Isotopes; Deuterium; Gas Chromatography-Mass Spectrometry; Glucose; Humans; Indicators and Reagents; Isotope Labeling; Isotopes; Leucine; Models, Biological; Oxidation-Reduction; Radioisotopes; Tyrosine | 1993 |
Dietary arginine uptake by the splanchnic region in adult humans.
Topics: Adult; Arginine; Carbon Isotopes; Deuterium; Diet; Humans; Infusions, Intravenous; Intubation, Gastrointestinal; Leucine; Male; Nitrogen Isotopes; Splanchnic Circulation | 1993 |
Plasma arginine kinetics in adult man: response to an arginine-free diet.
Topics: Adult; Arginine; Carbon Isotopes; Chromatography, High Pressure Liquid; Citrulline; Deuterium; Fasting; Food, Formulated; Humans; Infusions, Intravenous; Keto Acids; Leucine; Male; Nitrogen Isotopes; Ornithine; Time Factors; Urea | 1994 |
Plasma arginine and citrulline kinetics in adults given adequate and arginine-free diets.
Topics: Adult; Arginine; Carbon Isotopes; Citrulline; Deuterium; Diet; Humans; Isotope Labeling; Kinetics; Leucine; Male; Models, Biological; Urea | 1993 |
Use of 18O-labelled leucine and phenylalanine to measure protein turnover in muscle cell cultures and possible futile cycling during aminoacylation.
Topics: Acylation; Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Deuterium; Kinetics; Leucine; Muscle Proteins; Muscles; Oxygen Isotopes; Phenylalanine; Swine | 1993 |
Splanchnic metabolism of dietary arginine in relation to nitric oxide synthesis in normal adult man.
Topics: Adult; Arginine; Deuterium; Humans; Isotope Labeling; Leucine; Male; Nitrates; Nitric Oxide; Nitrogen Isotopes; Pilot Projects; Reference Values; Splanchnic Circulation | 1993 |
An isotopic study of the effect of dietary carbohydrate on the metabolic fate of dietary leucine and phenylalanine.
Topics: Adult; Blood Glucose; Carbon Isotopes; Deuterium; Diet; Dietary Carbohydrates; Humans; Keto Acids; Leucine; Male; Nitrogen Isotopes; Oxidation-Reduction; Phenylalanine; Splanchnic Circulation | 1993 |
Effects of protein restriction and acute refeeding on leucine and lysine kinetics in young men.
Topics: Adult; Carbon Isotopes; Deuterium; Dietary Proteins; Humans; Isotope Labeling; Keto Acids; Kinetics; Leucine; Lysine; Male; Nitrogen Isotopes; Protein Biosynthesis; Radioisotope Dilution Technique; Reference Values; Splanchnic Circulation | 1993 |
3-Hydroxyisovalerylcarnitine in 3-methylcrotonyl-CoA carboxylase deficiency.
Topics: Carbon-Carbon Ligases; Carnitine; Deuterium; Female; Fibroblasts; Gas Chromatography-Mass Spectrometry; Humans; Infant; Leucine; Ligases; Mass Spectrometry | 1995 |
Twenty-four-hour intravenous and oral tracer studies with L-[1-13C]phenylalanine and L-[3,3-2H2]tyrosine at a tyrosine-free, generous phenylalanine intake in adults.
Topics: Administration, Oral; Adult; Carbon Dioxide; Carbon Isotopes; Circadian Rhythm; Deuterium; Humans; Hydroxylation; Injections, Intravenous; Leucine; Male; Oxidation-Reduction; Phenylalanine; Tyrosine | 1996 |
Sensitive methods to study human apolipoprotein B metabolism using stable isotope-labeled amino acids.
Topics: Adult; Amino Acids; Apolipoproteins B; Deuterium; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Humans; Iodine Radioisotopes; Leucine; Lipoproteins, VLDL; Mass Spectrometry; Middle Aged; Models, Biological | 1996 |
Determination of isotopic ratios of L-leucine and L-phenylalanine and their stable isotope labeled analogues in biological samples by gas chromatography/triple-stage quadrupole mass spectrometry.
Topics: Apolipoprotein A-I; Apolipoproteins; Calibration; Carbon Isotopes; Deuterium; Esters; Gas Chromatography-Mass Spectrometry; Leucine; Lipoproteins; Molecular Structure; Phenylalanine | 1996 |
A dynamic bundle of four adjacent hydrophobic segments in the denatured state of staphylococcal nuclease.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Deuterium; Enzyme Stability; Hydrogen Bonding; Hydrogen-Ion Concentration; Leucine; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Models, Molecular; Mutation; Peptide Fragments; Protein Denaturation; Protein Structure, Secondary; Urea; Valine | 1996 |
Increased clearance of low density lipoprotein precursors in patients with heterozygous familial defective apolipoprotein B-100: a stable isotope approach.
Topics: Adult; Apolipoprotein B-100; Apolipoproteins B; Carbon Isotopes; Deuterium; Female; Heterozygote; Humans; Kinetics; Leucine; Lipids; Lipoproteins; Lipoproteins, LDL; Male; Metabolic Clearance Rate; Middle Aged; Mutation; Phenylalanine; Protein Precursors | 1996 |
Whole body protein metabolism in children with cancer.
Topics: Adolescent; Amino Acids; Carbon Isotopes; Child; Child, Preschool; Deuterium; Female; Humans; Kinetics; Leucine; Male; Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins; Tyrosine | 1996 |
Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM.
Topics: Apolipoproteins B; Cholesterol; Cholesterol, HDL; Deuterium; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucose Clamp Technique; Humans; Hyperglycemia; Hyperinsulinism; Infusions, Intravenous; Insulin; Leucine; Lipoproteins, VLDL; Liver; Male; Middle Aged; Models, Biological; Radioisotope Dilution Technique; Reference Values; Triglycerides | 1997 |
Hepatic protein synthesis in the sheep: effect of intake as monitored by use of stable-isotope-labelled glycine, leucine and phenylalanine.
Topics: Amino Acids; Animals; Apolipoprotein B-100; Apolipoproteins B; Carbon Isotopes; Deuterium; Energy Intake; Glycine; Leucine; Liver; Male; Phenylalanine; Protein Biosynthesis; Sheep | 1997 |
Mechanisms permitting nephrotic patients to achieve nitrogen equilibrium with a protein-restricted diet.
Topics: Adult; Aged; Carbon Isotopes; Deuterium; Diet, Protein-Restricted; Female; Humans; Kinetics; Leucine; Male; Mathematics; Middle Aged; Models, Biological; Nephrotic Syndrome; Nitrogen; Proteinuria; Reference Values | 1997 |
High density lipoprotein apolipoprotein AI kinetics in NIDDM: a stable isotope study.
Topics: Adult; Apolipoprotein A-I; Blood Glucose; Cholesterol; Cholesterol, HDL; Deuterium; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Kinetics; Leucine; Lipoproteins, HDL; Male; Middle Aged; Radioisotope Dilution Technique; Reference Values; Triglycerides | 1997 |
Effects of leucine on whole body leucine, valine, and threonine metabolism in humans.
Topics: Adult; Amino Acids; Biotransformation; Carbon Isotopes; Deuterium; Female; Hemiterpenes; Humans; Keto Acids; Kinetics; Leucine; Male; Radioisotope Dilution Technique; Threonine; Time Factors; Valine | 1997 |
Production of apolipoprotein B-67 in apolipoprotein B-67/B-100 heterozygotes: technical problems associated with leucine contamination in stable isotope studies.
Topics: Adult; Apolipoprotein B-100; Apolipoproteins B; Chromatography, Ion Exchange; Deuterium; Drug Contamination; Female; Heterozygote; Humans; Hypobetalipoproteinemias; Kinetics; Leucine; Lipoproteins; Lipoproteins, IDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged | 1997 |
Role of glutamine as a glucose precursor in fasting humans.
Topics: Adult; Amino Acids; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Carbon Radioisotopes; Deuterium; Energy Metabolism; Female; Gluconeogenesis; Glutamine; Humans; Isotope Labeling; Kinetics; Leucine; Male | 1997 |
[Detection of human proteins in vivo!].
Topics: Blood Proteins; Carbon Radioisotopes; Deuterium; Humans; Leucine; Metabolism, Inborn Errors; Phenylalanine | 1997 |
Measurement of albumin synthesis in humans using stable isotopes.
Topics: Acidosis; Carbon Isotopes; Deuterium; Humans; Injections, Intravenous; Insulin-Like Growth Factor I; Isotope Labeling; Leucine; Phenylalanine; Reference Values; Serum Albumin | 1997 |
Gut mucosal protein synthesis in fed and fasted humans.
Topics: Adolescent; Adult; Deuterium; Fasting; Food; Gas Chromatography-Mass Spectrometry; Humans; Injections, Intravenous; Intestinal Mucosa; Leucine; Male; Phenylalanine; Protein Biosynthesis; Radioactive Tracers; Reference Values; Stomach | 1998 |
Familial HDL deficiency characterized by hypercatabolism of mature apoA-I but not proapoA-I.
Topics: Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins; Deuterium; Electrophoresis, Gel, Two-Dimensional; Humans; Isoelectric Focusing; Kinetics; Leucine; Lipids; Lipoproteins; Lipoproteins, HDL; Tangier Disease | 1998 |
Improved accuracy and precision of gas chromatography/mass spectrometry measurements for metabolic tracers.
Topics: Adolescent; Adult; Carbon Isotopes; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Leucine; Male; Middle Aged; Nitrogen Isotopes; Osmolar Concentration; Palmitates; Urea | 1998 |
Acute-phase protein response to infection in severe malnutrition.
Topics: Acute-Phase Proteins; alpha 1-Antitrypsin; Child; Communicable Diseases; Deuterium; Dietary Proteins; Energy Intake; Female; Fibrinogen; Fluid Therapy; Haptoglobins; Humans; Leucine; Male; Orosomucoid; Protein-Energy Malnutrition; Time Factors | 1998 |
Hydroxyl radical-induced hydrogen/deuterium exchange in amino acid carbon-hydrogen bonds.
Topics: Amino Acids; Carbon; Chemical Phenomena; Chemistry, Physical; Deuterium; Dithiothreitol; Hydrogen; Hydroxyl Radical; Kinetics; Leucine; Mass Spectrometry; Sulfhydryl Reagents | 1999 |
Protein metabolism in glucagonoma.
Topics: Adult; Amino Acids; Blood Glucose; C-Peptide; Deuterium; Female; Glucagon; Glucagonoma; Humans; Infusions, Intravenous; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins; Reference Values; Tyrosine | 1999 |
Splanchnic uptake of leucine in healthy children and in children with cystic fibrosis.
Topics: Carbon Isotopes; Child; Cystic Fibrosis; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Intestinal Absorption; Leucine; Models, Biological; Reference Values; Splanchnic Circulation | 1999 |
A robust and cost-effective method for the production of Val, Leu, Ile (delta 1) methyl-protonated 15N-, 13C-, 2H-labeled proteins.
Topics: Carbon Isotopes; Deuterium; Indicators and Reagents; Isoleucine; Isotope Labeling; Leucine; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Valine | 1999 |
Identification of the sites of hydroxyl radical reaction with peptides by hydrogen/deuterium exchange: prevalence of reactions with the side chains.
Topics: Deuterium; Dithiothreitol; DNA Footprinting; Enkephalin, Leucine-2-Alanine; Hydrogen; Hydrogen Peroxide; Hydroxyl Radical; Iron; Leucine; Oligopeptides; Oxidation-Reduction; Peptide Fragments; Phenylalanine; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Tyrosine | 2000 |
Neighboring aliphatic/aromatic side chain interactions between residues 9 and 10 in gramicidin channels.
Topics: Amino Acid Sequence; Amino Acid Substitution; Chromatography, Gel; Circular Dichroism; Deuterium; Gramicidin; Ion Channels; Leucine; Lipid Bilayers; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Protein Conformation; Tryptophan | 2000 |
An innovative method for measuring hydrogen and deuterium: chemical reaction interface mass spectrometry with nitrogen reactant gas.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Deuterium; Hydrogen; Leucine; Mass Spectrometry; Neurotensin; Nitrogen | 2000 |
In vivo metabolism of ApoB, ApoA-I, and VLDL triglycerides in a form of hypobetalipoproteinemia not linked to the ApoB gene.
Topics: Adult; Apolipoprotein A-I; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Chromosomes, Human, Pair 2; Deuterium; Female; Genetic Linkage; Humans; Hyperlipoproteinemia Type II; Kinetics; Leucine; Lipoproteins, VLDL; Male; Middle Aged; Mutation; Triglycerides | 2000 |
Kinetics of L-[1-(13)C]leucine when ingested with free amino acids, unlabeled or intrinsically labeled casein.
Topics: Adult; Amino Acids; Carbon Dioxide; Carbon Isotopes; Caseins; Deuterium; Diet; Dietary Proteins; Female; Humans; Insulin; Keto Acids; Kinetics; Leucine; Male; Mesentery; Oxidation-Reduction | 2000 |
Evidence of Strecker aldehyde excretion by yeast in cold contact fermentations.
Topics: Aldehydes; Chromatography, Gas; Cold Temperature; Culture Media; Deuterium; Fermentation; Leucine; Saccharomyces cerevisiae | 2000 |
Assessment of the metabolic chiral inversion of D-leucine in rat by gas chromatography-mass spectrometry combined with a stable isotope dilution analysis.
Topics: Animals; Deuterium; Gas Chromatography-Mass Spectrometry; Infusions, Intravenous; Leucine; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2000 |
Measurement of skin protein breakdown in a rat model.
Topics: Animals; Blotting, Western; Carbon Isotopes; Collagen; Deuterium; Electrophoresis, Polyacrylamide Gel; Extracellular Space; Infusions, Intravenous; Intracellular Fluid; Keto Acids; Leucine; Male; Models, Biological; Phenylalanine; Proteins; Rats; Rats, Sprague-Dawley; Skin | 2000 |
Acute effects of low density lipoprotein apheresis on metabolic parameters of apolipoprotein B.
Topics: Adult; Apolipoproteins B; Blood Component Removal; Coronary Disease; Deuterium; Drug Resistance; Humans; Hyperlipoproteinemias; Kinetics; Leucine; Lipoproteins, LDL; Male; Middle Aged | 2000 |
Whole body protein kinetics in women: effect of pregnancy and IDDM during anabolic stimulation.
Topics: Amino Acids; Blood Glucose; Carbon Isotopes; Deuterium; Diabetes Mellitus, Type 1; Female; Glucose Clamp Technique; Humans; Hydroxylation; Insulin; Kinetics; Leucine; Oxidation-Reduction; Phenylalanine; Pregnancy; Pregnancy in Diabetics; Proteins | 2000 |
Human triglyceride-rich lipoprotein apo E kinetics and its relationship to LDL apo B-100 metabolism.
Topics: Adult; Aged; Apolipoprotein B-100; Apolipoproteins B; Apolipoproteins E; Cholesterol; Deuterium; Eating; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Kinetics; Leucine; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Triglycerides | 2001 |
A transition-state analogue reduces protein dynamics in hypoxanthine-guanine phosphoribosyltransferase.
Topics: Amino Acid Sequence; Binding Sites; Catalytic Domain; Chromatography, High Pressure Liquid; Deuterium; Diphosphates; Enzyme Inhibitors; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Leucine; Macromolecular Substances; Magnesium; Magnesium Compounds; Mass Spectrometry; Molecular Sequence Data; Pepsin A; Peptide Fragments; Phenylalanine; Protons; Pyrimidinones; Pyrroles | 2001 |
Synthesis of (13)C/D doubly labeled L-leucines: probes for conformational analysis of the leucine side-chain.
Topics: Carbon Isotopes; Deuterium; Isotope Labeling; Leucine; Magnetic Resonance Spectroscopy; Molecular Conformation | 2001 |
The presence of a hydrogen bond between asparagine 485 and the pi system of FAD modulates the redox potential in the reaction catalyzed by cholesterol oxidase.
Topics: Asparagine; Binding Sites; Catalysis; Cholesterol Oxidase; Crystallization; Crystallography, X-Ray; Deuterium; Flavin-Adenine Dinucleotide; Hydrogen Bonding; Kinetics; Leucine; Mutagenesis, Site-Directed; Oxidation-Reduction; Recombinant Proteins; Static Electricity; Streptomyces; Substrate Specificity | 2001 |
A new labeling approach using stable isotopes to study in vivo plasma cholesterol metabolism in humans.
Topics: Acetates; Adult; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins B; Biological Transport; Carbon Isotopes; Cholesterol; Cholesterol Esters; Deuterium; Esterification; Female; Humans; Infusions, Intravenous; Leucine; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Methods; Models, Biological; Reference Values | 2002 |
Glutamine and leucine nitrogen kinetics and their relation to urea nitrogen in newborn infants.
Topics: Blood Urea Nitrogen; Carbon Isotopes; Deuterium; Female; Glutamine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Kinetics; Leucine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Pregnancy; Pregnancy in Diabetics; Urea | 2002 |
Stable isotope labelling in vivo as an aid to protein identification in peptide mass fingerprinting.
Topics: Deuterium; Leucine; Peptide Fragments; Peptide Mapping; Proteins; Proteome; Saccharomyces cerevisiae Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2002 |
Oxazolinone derivative of leucine for GC-MS: a sensitive and robust method for stable isotope kinetic studies of lipoproteins.
Topics: Apolipoprotein A-I; Apolipoproteins B; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Isotope Labeling; Kinetics; Leucine; Lipoproteins; Oxazolone; Reproducibility of Results | 2002 |
Biosynthetic precursors of the lipase inhibitor lipstatin.
Topics: Animals; Catalysis; Chromatography, Thin Layer; Deuterium; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Lactones; Leucine; Lipase; Liver; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Orlistat; Streptomyces; Swine | 2002 |
Amino acid kinetics during the anhepatic phase of liver transplantation.
Topics: Alanine; Amino Acids; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Deuterium; Electrolytes; Fatty Acids, Nonesterified; Gluconeogenesis; Glutamine; Glycerol; Hematocrit; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Leucine; Liver; Liver Transplantation; Metabolic Clearance Rate; Middle Aged; Nitrogen; Oxygen; Pyruvic Acid | 2002 |
Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics.
Topics: 3T3 Cells; Amino Acids; Animals; Cell Culture Techniques; Cell Differentiation; Cell Line; Deuterium; Genetic Techniques; Hydrogen-Ion Concentration; Leucine; Mice; Muscles; Peptides; Proteomics; Time Factors; Up-Regulation | 2002 |
Response of splanchnic and whole-body leucine kinetics to treatment of children with edematous protein-energy malnutrition accompanied by infection.
Topics: Deuterium; Edema; Female; Humans; Infant; Infections; Keto Acids; Kinetics; Leucine; Male; Protein Biosynthesis; Protein-Energy Malnutrition; Proteins; Splanchnic Circulation; Weight Gain | 2002 |
Essential amino acids and muscle protein recovery from resistance exercise.
Topics: Adult; Blood Glucose; Carbon Isotopes; Deuterium; Exercise; Female; Humans; Insulin; Leucine; Male; Muscle, Skeletal; Nitrogen Isotopes; Phenylalanine; Protein Biosynthesis; Urea | 2002 |
Measuring synthesis rates of muscle creatine kinase and myosin with stable isotopes and mass spectrometry.
Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Creatine Kinase; Creatine Kinase, MM Form; Deuterium; Gas Chromatography-Mass Spectrometry; Half-Life; Isoenzymes; Kinetics; Leucine; Male; Molecular Weight; Muscle, Skeletal; Myocardium; Myosins; Peptide Fragments; Rats; Rats, Sprague-Dawley; Repetitive Sequences, Amino Acid; RNA, Transfer, Amino Acyl; Spectrometry, Mass, Electrospray Ionization; Trypsin | 2002 |
No effect of creatine supplementation on human myofibrillar and sarcoplasmic protein synthesis after resistance exercise.
Topics: Adult; Biopsy; Blood Flow Velocity; Carbon Isotopes; Creatine; Deuterium; Diet; Dietary Proteins; Dietary Supplements; Exercise; Humans; Kinetics; Leg; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Myofibrils; Phenylalanine; Polysaccharides; Sarcoplasmic Reticulum | 2003 |
ADAPTATION TO WIDE-SPREAD DISTURBANCE OF ENZYME FUNCTION.
Topics: Adaptation, Physiological; Biochemical Phenomena; Biochemistry; Deuterium; Enzymes; Fluorine; Leucine; Molecular Biology; Research | 1964 |
Insertion of externally administered amyloid beta peptide 25-35 and perturbation of lipid bilayers.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Deuterium; Fourier Analysis; Leucine; Lipid Bilayers; Models, Molecular; Neutron Diffraction; Peptide Fragments; Phosphatidylcholines; Phosphatidylethanolamines; Scattering, Radiation | 2003 |
Spectral deconvolution of chemical mixtures by covariance NMR.
Topics: Amino Acids; Buffers; Deuterium; Glutamic Acid; Leucine; Magnetic Resonance Spectroscopy; Principal Component Analysis; Valine | 2004 |
Examination of the rate of peptide biosynthesis in neuroendocrine cell lines using a stable isotopic label and mass spectrometry.
Topics: Amino Acid Sequence; Animals; beta-Lipotropin; Cell Line; Chloroquine; Colforsin; Culture Media, Conditioned; Deuterium; Hydrogen-Ion Concentration; Insulin; Islets of Langerhans; Leucine; Mass Spectrometry; Mice; Molecular Sequence Data; Nerve Tissue Proteins; Neuropeptides; Neurosecretory Systems; Pituitary Gland; Potassium Chloride; Rats; Stimulation, Chemical | 2004 |
Glutamine metabolism in Crohn's disease: a stable isotope study.
Topics: Adult; Calorimetry, Indirect; Carbon Isotopes; Case-Control Studies; Crohn Disease; Deuterium; Female; Glutamine; Humans; Infusions, Intravenous; Intubation, Gastrointestinal; Leucine; Male; Nutritional Requirements; Oxygen Consumption; Splanchnic Circulation | 2004 |
A new combined multicompartmental model for apolipoprotein B-100 and triglyceride metabolism in VLDL subfractions.
Topics: Apolipoprotein B-100; Apolipoproteins B; Deuterium; Glycerol; Humans; Kinetics; Leucine; Lipoproteins, VLDL; Models, Biological; Protein Transport; Triglycerides | 2005 |
Supplementation with aromatic amino acids improves leucine kinetics but not aromatic amino acid kinetics in infants with infection, severe malnutrition, and edema.
Topics: Alanine; Amino Acids, Aromatic; Anthropometry; Body Water; Deuterium; Edema; Enteral Nutrition; Humans; Infant; Infections; Intubation, Gastrointestinal; Kinetics; Leucine; Phenylalanine; Protein-Energy Malnutrition; Proteins; Tryptophan; Tyrosine | 2004 |
Investigating the dynamic properties of the transmembrane segment of phospholamban incorporated into phospholipid bilayers utilizing 2H and 15N solid-state NMR spectroscopy.
Topics: Amino Acid Sequence; Calcium-Binding Proteins; Deuterium; Leucine; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Proteins; Molecular Sequence Data; Nitrogen Isotopes; Peptide Fragments; Phospholipids; Protein Conformation; Protein Structure, Secondary; Temperature; Thermodynamics | 2004 |
Investigations of polypeptide rotational diffusion in aligned membranes by 2H and 15N solid-state NMR spectroscopy.
Topics: Alanine; Deuterium; Diffusion; Leucine; Lipid Bilayers; Membrane Proteins; Membranes, Artificial; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Protein Structure, Secondary | 2004 |
The metabolism of apolipoproteins (a) and B-100 within plasma lipoprotein (a) in human beings.
Topics: Adult; Aged; Apolipoprotein B-100; Apolipoproteins A; Apolipoproteins B; Deuterium; Female; Food; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Leucine; Lipoprotein(a); Male; Middle Aged; Regression Analysis | 2005 |
Accurate determination of leucine and valine side-chain conformations using U-[15N/13C/2H]/[1H-(methine/methyl)-Leu/Val] isotope labeling, NOE pattern recognition, and methine Cgamma-Hgamma/Cbeta-Hbeta residual dipolar couplings: application to the 34-kDa
Topics: Carbon Isotopes; Deuterium; Disaccharides; Isotope Labeling; Leucine; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphotransferases; Protein Conformation; Valine | 2005 |
Characterization of dynamic processes using deuterium in uniformly 2H,13C,15N enriched peptides by MAS solid-state NMR.
Topics: Acetylcysteine; Carbon Isotopes; Deuterium; Leucine; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Peptides; Signal Processing, Computer-Assisted; Valine | 2006 |
Quantitative 13C and 2H NMR relaxation studies of the 723-residue enzyme malate synthase G reveal a dynamic binding interface.
Topics: Acetyl Coenzyme A; Binding Sites; Carbon Isotopes; Deuterium; Isoenzymes; Isoleucine; Leucine; Malate Synthase; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Pyruvic Acid; Valine | 2005 |
Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC).
Topics: Actinin; Animals; Cell Line; Cytoskeletal Proteins; Deuterium; Glucose Transporter Type 4; Immunoprecipitation; Insulin; Isotope Labeling; Leucine; Microfilament Proteins; Myoblasts, Skeletal; Protein Interaction Mapping; Protein Transport; Proteins; Rats | 2006 |
Improved isotopic deuterium labeling at the diastereotopic methyl group of leucine: a synthetic route to (4S)- and (4R)-[5-2H1]leucine.
Topics: Deuterium; Isotope Labeling; Leucine; Methylation; Molecular Structure; Stereoisomerism | 2006 |
Evaluation of D10-Leu metabolic labeling coupled with MALDI-MS analysis in studying the response of the yeast proteome to H2O2 challenge.
Topics: Deuterium; Glycolysis; Hydrogen Peroxide; Leucine; Oxidative Stress; Proteome; Proteomics; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2006 |
Analysis of the protein complex associated with 14-3-3 epsilon by a deuterated-leucine labeling quantitative proteomics strategy.
Topics: 14-3-3 Proteins; Cell Line; Deuterium; Humans; Leucine; Protein Binding; Protein Interaction Mapping; Proteomics; Staining and Labeling | 2009 |
Application of the SILAC (stable isotope labelling with amino acids in cell culture) technique in quantitative comparisons for tissue proteome expression.
Topics: Amino Acid Sequence; Cell Line; Deuterium; Down-Regulation; Electron Transport Complex IV; Enoyl-CoA Hydratase; Humans; Immunohistochemistry; Isotope Labeling; Kidney Neoplasms; Leucine; Molecular Sequence Data; Proteome; Proteomics; Reproducibility of Results; Tandem Mass Spectrometry; Tumor Cells, Cultured; Vimentin | 2009 |
Fibrinogen kinetics and protein turnover in hypertension: Effects of insulin.
Topics: Adult; Biomarkers; Blood Glucose; Case-Control Studies; Deuterium; Fibrinogen; Glucose; Glucose Clamp Technique; Humans; Hyperinsulinism; Hypertension; Indicator Dilution Techniques; Infusions, Intravenous; Insulin; Kinetics; Leucine; Male; Middle Aged; Peptide Hydrolases; Up-Regulation | 2009 |
Efforts toward developing probes of protein dynamics: vibrational dephasing and relaxation of carbon-deuterium stretching modes in deuterated leucine.
Topics: Carbon; Deuterium; Leucine; Proteins | 2009 |
Carbon-deuterium vibrational probes of amino acid protonation state.
Topics: Amino Acids; Carbon; Computer Simulation; Deuterium; Leucine; Models, Chemical; Molecular Probes; Proteins; Protons; Vibration | 2009 |
The production of intrinsically labeled milk protein provides a functional tool for human nutrition research.
Topics: Absorption; Animals; Carbon Isotopes; Cattle; Deuterium; Dietary Proteins; Digestion; Female; Humans; Isotope Labeling; Leucine; Male; Middle Aged; Milk; Milk Proteins; Muscle Proteins; Nutritional Physiological Phenomena; Phenylalanine; Research; Tyrosine | 2009 |
A solid-state deuterium NMR and sum-frequency generation study of the side-chain dynamics of peptides adsorbed onto surfaces.
Topics: Adsorption; Amino Acid Sequence; Deuterium; Hydrophobic and Hydrophilic Interactions; Leucine; Lysine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Peptides | 2009 |
Probing the dynamics of a protein hydrophobic core by deuteron solid-state nuclear magnetic resonance spectroscopy.
Topics: Animals; Chickens; Computer Simulation; Deuterium; Hydrophobic and Hydrophilic Interactions; Leucine; Models, Chemical; Neurofilament Proteins; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Structure, Secondary | 2009 |
Glucosylthioureidocalix[4]arenes: Synthesis, conformations and gas phase recognition of amino acids.
Topics: Amino Acids; Deuterium; Gases; Hydrogen; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Molecular Conformation; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Tryptophan; Tyrosine | 2010 |
Optimal methyl labeling for studies of supra-molecular systems.
Topics: Carbon Isotopes; Deuterium; Isoleucine; Leucine; Methylation; Nuclear Magnetic Resonance, Biomolecular; Proteasome Endopeptidase Complex; Proteins; Valine | 2010 |
High-resolution methyl edited GFT NMR experiments for protein resonance assignments and structure determination.
Topics: Amino Acid Sequence; Carbon Isotopes; Deuterium; Escherichia coli; Fourier Analysis; Humans; Isoleucine; Leucine; Methylation; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Quaternary; Proteins; Valine | 2010 |
A simple strategy for ¹³C, ¹H labeling at the Ile-γ2 methyl position in highly deuterated proteins.
Topics: Carbon Isotopes; Deuterium; Isoleucine; Isotope Labeling; Leucine; Nuclear Magnetic Resonance, Biomolecular; Proteasome Endopeptidase Complex; Proteins; Valine; Vitamin B 12 | 2010 |
Membrane-perturbing properties of two Arg-rich paddle domains from voltage-gated sensors in the KvAP and HsapBK K(+) channels.
Topics: Aeropyrum; Amino Acid Sequence; Arginine; Cell Membrane; Circular Dichroism; Deuterium; Fluoresceins; Humans; Large-Conductance Calcium-Activated Potassium Channels; Leucine; Lipid Bilayers; Magnetic Resonance Imaging; Molecular Sequence Data; Potassium Channels, Voltage-Gated; Protein Conformation; Protein Structure, Tertiary | 2012 |
In vivo stable-isotope kinetic study suggests intracellular assembly of lipoprotein(a).
Topics: Adult; Apolipoprotein B-100; Apolipoproteins A; Deuterium; Humans; Infusions, Intravenous; Kinetics; Leucine; Lipoprotein(a); Lipoproteins, LDL; Male; Middle Aged; Models, Biological; Protein Multimerization; Young Adult | 2012 |
Brief early-life non-specific incorporation of deuterium extends mean life span in Drosophila melanogaster without affecting fecundity.
Topics: Analysis of Variance; Animals; Deuterium; Drosophila melanogaster; Female; Fertility; Isoleucine; Leucine; Longevity; Male; Mass Spectrometry; Proportional Hazards Models; Survival Analysis; Time Factors | 2013 |
Perdeuteration and methyl-selective (1)H, (13)C-labeling by using a Kluyveromyces lactis expression system.
Topics: Carbon Isotopes; Deuterium; Gene Expression; Isoleucine; Isotope Labeling; Kluyveromyces; Leucine; Maltose-Binding Proteins; Nuclear Magnetic Resonance, Biomolecular; Proteins; Transaminases; Valine | 2013 |
Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart.
Topics: Age Factors; Animals; Caloric Restriction; Cardiovascular Diseases; Deuterium; Female; Heart; Leucine; Mice; Mice, Inbred C57BL; Myocardium; Proteome; Random Allocation; Sirolimus; Ventricular Remodeling | 2014 |
A novel ApoA-I truncation (ApoA-IMytilene) associated with decreased ApoA-I production.
Topics: Adult; Aged; Apolipoprotein A-I; Cholesterol, HDL; Codon, Nonsense; Coronary Disease; Deuterium; Humans; Kinetics; Leucine; Lipoprotein(a); Male; Middle Aged; Pedigree | 2014 |
Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects.
Topics: Aging; Animals; Caloric Restriction; Deuterium; Eukaryotic Initiation Factor-2; Female; Gene Expression Regulation; Half-Life; Homeostasis; Isotope Labeling; Leucine; Liver; Mice; Mice, Inbred C57BL; Polyribosomes; Protein Biosynthesis; Protein Stability; Proteolysis; Proteome; Signal Transduction; Sirolimus; Tandem Mass Spectrometry; TOR Serine-Threonine Kinases | 2015 |
Development and characterization of novel 8-plex DiLeu isobaric labels for quantitative proteomics and peptidomics.
Topics: Chromatography, Liquid; Deuterium; Leucine; Peptides; Proteomics; Saccharomyces cerevisiae; Tandem Mass Spectrometry | 2015 |
Probing the Secondary Structure of Membrane Peptides Using (2)H-Labeled d(10)-Leucine via Site-Directed Spin-Labeling and Electron Spin Echo Envelope Modulation Spectroscopy.
Topics: Deuterium; Electrons; Leucine; Peptides; Protein Structure, Secondary; Spectrum Analysis; Spin Labels | 2016 |
Detection of intermolecular transferred NOEs in large protein complexes using asymmetric deuteration: HIV-1 gp120 in complex with a CCR5 peptide.
Topics: Binding Sites; Crystallography, X-Ray; Deuterium; HIV Envelope Protein gp120; Humans; Isoleucine; Leucine; Multiprotein Complexes; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Binding; Protons; Receptors, CCR5; Tyrosine; Valine | 2016 |
Presleep protein ingestion does not compromise the muscle protein synthetic response to protein ingested the following morning.
Topics: Adult; Carbon Isotopes; Deuterium; Dietary Carbohydrates; Dietary Proteins; Exercise; Healthy Volunteers; Humans; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Protein Biosynthesis; Resistance Training; Sleep; Young Adult | 2016 |
SRM-based measurements of proprotein convertase subtilisin/kexin type 9 and lipoprotein(a) kinetics in nonhuman primate serum.
Topics: Animals; Chromatography, Affinity; Chromatography, High Pressure Liquid; Deuterium; Humans; Isotope Labeling; Leucine; Lipoprotein(a); Male; Mass Spectrometry; Peptides; Primates; Proprotein Convertase 9; Trypsin | 2016 |
Deuterium incorporation experiments from (3R)- and (3S)-[3-
Topics: Deuterium; Halobacterium salinarum; Isovaleryl-CoA Dehydrogenase; Leucine; Lipid Metabolism; Lipids; Terpenes | 2017 |
Determination of methyl order parameters using solid state NMR under off magic angle spinning.
Topics: Animals; Anisotropy; Chickens; Deuterium; Leucine; Nuclear Magnetic Resonance, Biomolecular; Proteins; Spectrin; Valine | 2019 |
Hydrogen-Deuterium Exchange Mass Spectrometry Identifies Activated Factor IX-Induced molecular Changes in Activated Factor VIII.
Topics: Blood Coagulation; Deuterium; Deuterium Exchange Measurement; Factor IXa; Factor VIIIa; Hemophilia A; Humans; Leucine; Mass Spectrometry; Molecular Conformation; Mutagenesis, Site-Directed; Protein Binding; Surface Plasmon Resonance; Tyrosine | 2021 |