Compounds > deuterium

Page last updated: 2024-08-22

deuterium and hydroxycotinine

deuterium has been researched along with hydroxycotinine in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (16.67)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (66.67)	29.6817
2010's	1 (16.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benowitz, NL; Jacob, P; Shulgin, AT	1
Benowitz, NL; Jacob, P; Lessov-Schlaggar, CN; Swan, GE; Tyndale, RF	1
Benowitz, NL; Hukkanen, J; Jacob, P	1
Benowitz, NL; Dempsey, DA; Levi, M; Sheiner, LB	1
Benowitz, NL; Krasnow, RE; Lessov-Schlaggar, CN; Mwenifumbo, JC; Swan, GE; Tyndale, RF; Zhou, Q	1
Benowitz, NL; Moscicki, AB; Rait, MA; Rubinstein, ML; Sen, S; Shiffman, S	1

Trials

4 trial(s) available for deuterium and hydroxycotinine

Article	Year
CYP2A6 genotype and the metabolism and disposition kinetics of nicotine. Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:5 Topics: Adolescent; Adult; Aged; Alleles; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cotinine; Cytochrome P-450 CYP2A6; Deuterium; Dose-Response Relationship, Drug; Ganglionic Stimulants; Gene Frequency; Glucuronides; Half-Life; Humans; Infusions, Intravenous; Isoenzymes; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Nicotine; Polymorphism, Genetic; Time Factors; Twins	2006
Effect of grapefruit juice on cytochrome P450 2A6 and nicotine renal clearance. Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:5 Topics: Administration, Oral; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Beverages; Citrus paradisi; Cotinine; Cytochrome P-450 CYP2A6; Deuterium; Female; Ganglionic Stimulants; Glucuronides; Half-Life; Humans; Kidney; Liver; Male; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Nicotine	2006
Population pharmacokinetics of nicotine and its metabolites I. Model development. Journal of pharmacokinetics and pharmacodynamics, 2007, Volume: 34, Issue:1 Topics: Administration, Oral; Adult; Aryl Hydrocarbon Hydroxylases; Biological Availability; Biotransformation; Cotinine; Cytochrome P-450 CYP2A6; Deuterium; Female; Half-Life; Humans; Liver; Male; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Models, Biological; Models, Statistical; Nicotine; Nicotinic Agonists; Population Surveillance; Predictive Value of Tests; Reference Values; Saliva	2007
Identification of novel CYP2A61B variants: the CYP2A61B allele is associated with faster in vivo nicotine metabolism. Clinical pharmacology and therapeutics, 2008, Volume: 83, Issue:1 Topics: 3' Flanking Region; Aryl Hydrocarbon Hydroxylases; Base Sequence; Biotransformation; Cotinine; Cytochrome P-450 CYP2A6; Deuterium; Gene Frequency; Genetic Linkage; Genotype; Glucuronates; Humans; Infusions, Intravenous; Mixed Function Oxygenases; Molecular Sequence Data; Nicotine; Nicotinic Agonists; Phenotype; Polymorphism, Genetic; Sequence Alignment; Substrate Specificity	2008

Other Studies

2 other study(ies) available for deuterium and hydroxycotinine

Article	Year
Recent studies of nicotine metabolism in humans. Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:1 Topics: Adult; Cotinine; Deuterium; Humans; Infusions, Intravenous; Male; Nicotine; Smoking	1988
Nicotine metabolism and addiction among adolescent smokers. Addiction (Abingdon, England), 2013, Volume: 108, Issue:2 Topics: Adolescent; Behavior, Addictive; Chromatography, Liquid; Cotinine; Deuterium; Female; Humans; Male; Prospective Studies; Saliva; Self Report; Smoking; Tandem Mass Spectrometry; Tobacco Use Disorder	2013