Page last updated: 2024-08-22

deuterium and guanidine

deuterium has been researched along with guanidine in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (10.00)	18.7374
1990's	12 (30.00)	18.2507
2000's	19 (47.50)	29.6817
2010's	4 (10.00)	24.3611
2020's	1 (2.50)	2.80

Authors

Authors	Studies
Antonino, LC; Fink, AL; Fox, RO; Kautz, RA; Nakano, T	1
Brems, DN; Brown, PL; Nakagawa, SH; Tager, HS	1
Creighton, DJ; Pourmotabbed, T; Shih, MJ	1
Blond-Elguindi, S; Friguet, B; Goldberg, ME	1
Farmer, BT; Venters, RA	1
Houry, WA; Scheraga, HA	1
Clarke, AR; Parker, MJ	1
Baker, D; Gladwin, ST; Scalley, ML; Simons, KT; Yi, Q	1
Bhuyan, AK; Udgaonkar, JB	2
Handel, T; Kern, G; Marqusee, S	1
Gehrig, P; Plückthun, A; Ramm, K	1
Shortle, D; Wrabl, J	1
Dahlquist, FW; Gillespie, B; Llinás, M; Marqusee, S	1
Chen, J; Smith, DL	1
Fan, YX; McPhie, P; Miles, EW	1
Demura, M; Kobashigawa, Y; Koshiba, T; Kumaki, Y; Kuwajima, K; Nitta, K	1
Hsieh, H; Kumar, TK; Samuel, D; Srimathi, T; Yu, C	1
Clarke, J; Cota, E; Fowler, SB; Hamill, SJ	1
Marqusee, S; Parker, MJ	1
Arrington, CB; Robertson, AD; Sivaraman, T	1
Fischer, CJ; Gafni, A; Schauerte, JA; Steel, DG; Wisser, KC	1
Bieri, O; Kiefhaber, T	1
Bai, Y; Chu, R; Pei, W; Takei, J	1
Kallenbach, NR; Olson, CA; Shi, Z; Sosnick, TR	1
Jonsson, BH; Kjellsson, A; Sethson, I	1
Rush, TS; Speare, JO	1
Pan, H; Smith, DL	1
LWOFF, A; LWOFF, M	1
CARP, RI	1
Forest, E; Marcillat, O; Mazon, H; Smith, DL; Vial, C	1
Baran, J; Drozd, M; Pietraszko, A	1
Chugh, J; Hosur, RV; Sharma, S	1
Bolon, D; Deshaies, RJ; Fushman, D; Haririnia, A; Purohit, N; Twarog, MZ; Verma, R	1
Udgaonkar, JB; Wani, AH	1
Xiao, G; Zhang, A; Zhang, Z	1
Amyes, TL; Gerlt, JA; Goldman, LM; Goryanova, B; Richard, JP	1
Chin, J; Lough, AJ; Moozeh, K; So, SM	1
Kammari, R; Topp, EM	1
Kato, K; Kuwajima, K; Yagi-Utsumi, M; Yanaka, S	1

Other Studies

40 other study(ies) available for deuterium and guanidine

Article	Year
Cold denaturation and 2H2O stabilization of a staphylococcal nuclease mutant. Proceedings of the National Academy of Sciences of the United States of America, 1991, Sep-01, Volume: 88, Issue:17 Topics: Calorimetry; Circular Dichroism; Cold Temperature; Concanavalin A; Deuterium; Deuterium Oxide; Enzyme Stability; Guanidine; Guanidines; Kinetics; Micrococcal Nuclease; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Recombinant Proteins; Spectrometry, Fluorescence; Thermodynamics; Thiocyanates; Water	1991
The conformational stability and flexibility of insulin with an additional intramolecular cross-link. The Journal of biological chemistry, 1991, Jan-25, Volume: 266, Issue:3 Topics: Animals; Circular Dichroism; Cross-Linking Reagents; Deuterium; Guanidine; Guanidines; In Vitro Techniques; Insulin; Motion; Protein Conformation; Protein Denaturation; Swine	1991
Bovine liver formaldehyde dehydrogenase. Kinetic and molecular properties. The Journal of biological chemistry, 1989, Oct-15, Volume: 264, Issue:29 Topics: Aldehyde Oxidoreductases; Animals; Binding Sites; Catalysis; Cattle; Deuterium; Guanidine; Guanidines; Humans; Isoelectric Point; Isoenzymes; Kinetics; Liver; Molecular Weight; NAD; Protein Denaturation; Urea	1989
Renaturation of guanidine-unfolded tryptophan synthase by multi-mixing stopped-flow dilution in D2O. FEBS letters, 1988, Dec-05, Volume: 241, Issue:1-2 Topics: Deuterium; Deuterium Oxide; Guanidine; Guanidines; Kinetics; Protein Conformation; Protein Denaturation; Tryptophan Synthase; Water	1988
Assignment of aliphatic side-chain 1HN/15N resonances in perdeuterated proteins. Journal of biomolecular NMR, 1996, Volume: 7, Issue:1 Topics: Amino Acid Sequence; Amino Acids; Arginine; Asparagine; Deuterium; Glutamine; Guanidine; Guanidines; Humans; Hydrogen; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Protein Conformation; Protein Folding; Protein Structure, Secondary; Proteins; Sensitivity and Specificity	1996
Structure of a hydrophobically collapsed intermediate on the conformational folding pathway of ribonuclease A probed by hydrogen-deuterium exchange. Biochemistry, 1996, Sep-10, Volume: 35, Issue:36 Topics: Amides; Amino Acid Sequence; Animals; Cattle; Deuterium; Guanidine; Guanidines; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Ribonuclease, Pancreatic	1996
Amide backbone and water-related H/D isotope effects on the dynamics of a protein folding reaction. Biochemistry, 1997, May-13, Volume: 36, Issue:19 Topics: Amides; Animals; CD2 Antigens; Deuterium; Guanidine; Guanidines; Kinetics; Protein Denaturation; Protein Folding; Rats; Solubility; Water	1997
Characterization of the free energy spectrum of peptostreptococcal protein L. Folding & design, 1997, Volume: 2, Issue:5 Topics: Bacterial Proteins; Deuterium; Guanidine; Hot Temperature; Hydrogen; Models, Chemical; Peptostreptococcus; Protein Denaturation; Protein Folding; Thermodynamics	1997
Two structural subdomains of barstar detected by rapid mixing NMR measurement of amide hydrogen exchange. Proteins, 1998, Feb-15, Volume: 30, Issue:3 Topics: Amides; Bacillus; Bacterial Proteins; Circular Dichroism; Deuterium; Fluorescence; Guanidine; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Thermodynamics	1998
Stopped-flow NMR measurement of hydrogen exchange rates in reduced horse cytochrome c under strongly destabilizing conditions. Proteins, 1998, Aug-01, Volume: 32, Issue:2 Topics: Animals; Cytochrome c Group; Deuterium; Enzyme Stability; Guanidine; Horses; Hydrogen; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Protein Denaturation; Protein Folding; Protons; Thermodynamics	1998
Characterization of a folding intermediate from HIV-1 ribonuclease H. Protein science : a publication of the Protein Society, 1998, Volume: 7, Issue:10 Topics: Circular Dichroism; Deuterium; Drug Design; Enzyme Inhibitors; Enzyme Stability; Guanidine; HIV-1; Hydrogen; Kinetics; Models, Molecular; Mutation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Ribonuclease H; Viral Proteins	1998
Removal of the conserved disulfide bridges from the scFv fragment of an antibody: effects on folding kinetics and aggregation. Journal of molecular biology, 1999, Jul-09, Volume: 290, Issue:2 Topics: Conserved Sequence; Deuterium; Disulfides; Guanidine; Humans; Hydrogen; Immunoglobulin Fragments; Immunoglobulin Variable Region; Isomerism; Kinetics; Mass Spectrometry; Mutation; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Solubility; Spectrometry, Fluorescence; Thermodynamics	1999
A model of the changes in denatured state structure underlying m value effects in staphylococcal nuclease. Nature structural biology, 1999, Volume: 6, Issue:9 Topics: Amino Acid Substitution; Deuterium; Deuterium Oxide; Fluorescence; Guanidine; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Models, Molecular; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protons; Solvents; Staphylococcus; Thermodynamics	1999
The energetics of T4 lysozyme reveal a hierarchy of conformations. Nature structural biology, 1999, Volume: 6, Issue:11 Topics: Bacteriophage T4; Deuterium; Guanidine; Hydrogen; Kinetics; Models, Molecular; Muramidase; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Thermodynamics	1999
Unfolding and disassembly of the chaperonin GroEL occurs via a tetradecameric intermediate with a folded equatorial domain. Biochemistry, 2000, Apr-18, Volume: 39, Issue:15 Topics: Amino Acid Sequence; Chaperonin 60; Chromatography, Gel; Deuterium; Deuterium Oxide; Escherichia coli; Guanidine; Kinetics; Light; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Molecular Weight; Pepsin A; Peptide Fragments; Protein Denaturation; Protein Folding; Protein Structure, Quaternary; Protein Structure, Tertiary; Scattering, Radiation; Thermodynamics; Urea	2000
Regulation of tryptophan synthase by temperature, monovalent cations, and an allosteric ligand. Evidence from Arrhenius plots, absorption spectra, and primary kinetic isotope effects. Biochemistry, 2000, Apr-25, Volume: 39, Issue:16 Topics: Allosteric Regulation; Allosteric Site; Catalysis; Cations, Monovalent; Cesium; Chlorides; Deuterium; Enzyme Activation; Glycerophosphates; Guanidine; Kinetics; Ligands; Protein Conformation; Salmonella typhimurium; Serine; Sodium Chloride; Spectrum Analysis; Temperature; Thermodynamics; Tryptophan Synthase	2000
Hydrogen exchange study of canine milk lysozyme: stabilization mechanism of the molten globule. Proteins, 2000, Sep-01, Volume: 40, Issue:4 Topics: Amides; Amino Acid Sequence; Animals; Circular Dichroism; Deuterium; Dogs; Guanidine; Horses; Indicators and Reagents; Lactalbumin; Magnetic Resonance Spectroscopy; Milk; Models, Molecular; Molecular Sequence Data; Muramidase; Protein Folding; Protein Structure, Secondary; Spectrometry, Fluorescence; Thermodynamics	2000
Identification and characterization of an equilibrium intermediate in the unfolding pathway of an all beta-barrel protein. The Journal of biological chemistry, 2000, Nov-10, Volume: 275, Issue:45 Topics: Anilino Naphthalenesulfonates; Chromatography; Densitometry; Deuterium; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Fluorescent Dyes; Guanidine; Heparin; Humans; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Spectrometry, Fluorescence; Time Factors; Urea	2000
Two proteins with the same structure respond very differently to mutation: the role of plasticity in protein stability. Journal of molecular biology, 2000, Sep-22, Volume: 302, Issue:3 Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Deuterium; Fibronectins; Guanidine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Pliability; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Protons; Sequence Alignment; Sequence Deletion; Solvents; Tenascin; Thermodynamics	2000
A kinetic folding intermediate probed by native state hydrogen exchange. Journal of molecular biology, 2001, Jan-19, Volume: 305, Issue:3 Topics: Animals; CD2 Antigens; Deuterium; Fluorescence; Guanidine; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Protein Denaturation; Protein Folding; Protein Renaturation; Protein Structure, Tertiary; Rats; Thermodynamics	2001
Kinetics of unfolding and folding from amide hydrogen exchange in native ubiquitin. Nature structural biology, 2001, Volume: 8, Issue:4 Topics: Deuterium; Guanidine; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Protein Denaturation; Protein Folding; Thermodynamics; Ubiquitins	2001
Differences in the pathways for unfolding and hydrogen exchange among mutants of Escherichia coli alkaline phosphatase. Biochimica et biophysica acta, 2001, Feb-09, Volume: 1545, Issue:1-2 Topics: Alkaline Phosphatase; Bacterial Proteins; Deuterium; Escherichia coli; Guanidine; Hydrogen; Hydrogen Bonding; Kinetics; Luminescent Measurements; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Protein Folding; Recombinant Fusion Proteins; Thermodynamics; Tryptophan	2001
Origin of apparent fast and non-exponential kinetics of lysozyme folding measured in pulsed hydrogen exchange experiments. Journal of molecular biology, 2001, Jul-20, Volume: 310, Issue:4 Topics: Amides; Animals; Computer Simulation; Deuterium; Guanidine; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Muramidase; Protein Denaturation; Protein Folding; Protein Renaturation; Protein Structure, Secondary; Protein Structure, Tertiary; Protons; Solvents; Spectrometry, Mass, Electrospray Ionization	2001
Relationship between the native-state hydrogen exchange and folding pathways of a four-helix bundle protein. Biochemistry, 2002, Jun-25, Volume: 41, Issue:25 Topics: Amides; Apoproteins; Cytochrome b Group; Deuterium; Guanidine; Hydrogen; Hydrogen Bonding; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Protein Denaturation; Protein Engineering; Protein Folding; Protein Structure, Secondary; Protons; Thermodynamics	2002
D/H amide isotope effect in model alpha-helical peptides. Journal of the American Chemical Society, 2002, Nov-27, Volume: 124, Issue:47 Topics: Alanine; Amides; Amino Acid Sequence; Circular Dichroism; Deuterium; DNA-Binding Proteins; Guanidine; Kinetics; Molecular Sequence Data; Peptides; Protein Kinases; Protein Structure, Secondary; Saccharomyces cerevisiae Proteins	2002
Hydrogen exchange in a large 29 kD protein and characterization of molten globule aggregation by NMR. Biochemistry, 2003, Jan-21, Volume: 42, Issue:2 Topics: Amides; Carbonic Anhydrase I; Deuterium; Guanidine; Humans; Models, Chemical; Molecular Weight; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protons; Spectrometry, Fluorescence; Structure-Activity Relationship; Thermodynamics	2003
IR spectra of cytochrome c denatured with deuterated guanidine hydrochloride show increase in beta sheet. Biopolymers, 2003, Volume: 72, Issue:3 Topics: Animals; Cytochrome c Group; Deuterium; Guanidine; Horses; Protein Denaturation; Spectroscopy, Fourier Transform Infrared	2003
Quaternary structure of aldolase leads to differences in its folding and unfolding intermediates. Biochemistry, 2003, May-20, Volume: 42, Issue:19 Topics: Animals; Chromatography, High Pressure Liquid; Deuterium; Enzyme Stability; Fructose-Bisphosphate Aldolase; Guanidine; Hydrogen; In Vitro Techniques; Mass Spectrometry; Models, Molecular; Muscles; Peptide Fragments; Protein Denaturation; Protein Folding; Protein Structure, Quaternary; Protein Structure, Tertiary; Rabbits	2003
[A POLIOVIRUS MUTANT INSENSITIVE TO THE EFFECTS OF DEUTERATION]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Mar-02, Volume: 258 Topics: Deuterium; Enterovirus C, Human; Guanidine; Guanidines; Mutation; Poliovirus; Research	1964
STUDIES ON THE GUANIDINE CHARACTER OF POLIOVIRUS. Virology, 1964, Volume: 22 Topics: Animals; Cattle; Deuterium; Guanidine; Guanidines; Pharmacology; Poliovirus; Research; RNA; RNA, Viral; Serum Albumin; Serum Albumin, Bovine	1964
Conformational dynamics of the GdmHCl-induced molten globule state of creatine kinase monitored by hydrogen exchange and mass spectrometry. Biochemistry, 2004, May-04, Volume: 43, Issue:17 Topics: Animals; Circular Dichroism; Creatine Kinase; Deuterium; Guanidine; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Muscles; Protein Conformation; Protein Denaturation; Protein Folding; Rabbits; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Temperature	2004
Diguanidinium hydrogenarsenate monohydrate and its deuterated analogue vibrational, DSC and X-ray investigations. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2005, Volume: 61, Issue:13-14 Topics: Arsenates; Calorimetry, Differential Scanning; Crystallography, X-Ray; Deuterium; Guanidine; Hydrogen Bonding; Ions; Molecular Conformation; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Vibration	2005
Pockets of short-range transient order and restricted topological heterogeneity in the guanidine-denatured state ensemble of GED of dynamin. Biochemistry, 2007, Oct-23, Volume: 46, Issue:42 Topics: Amino Acid Sequence; Circular Dichroism; Cloning, Molecular; Deuterium; DNA, Complementary; Dynamin I; Escherichia coli; Guanidine; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Plasmids; Proline; Protein Conformation; Protein Denaturation; Protein Structure, Tertiary; Spectrometry, Fluorescence; Temperature; Time Factors	2007
Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins. Journal of molecular biology, 2008, Jan-25, Volume: 375, Issue:4 Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Carrier Proteins; Deuterium; DNA-Binding Proteins; Dose-Response Relationship, Drug; Glutathione Transferase; Glycine; Guanidine; Humans; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ligands; Lysine; Models, Molecular; Mutation; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; Substrate Specificity; Temperature; Thermodynamics; Ubiquitin; Ubiquitination	2008
Native state dynamics drive the unfolding of the SH3 domain of PI3 kinase at high denaturant concentration. Proceedings of the National Academy of Sciences of the United States of America, 2009, Dec-08, Volume: 106, Issue:49 Topics: Deuterium; Deuterium Exchange Measurement; Enzyme Stability; Guanidine; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Molecular Weight; Peptides; Phosphatidylinositol 3-Kinases; Protein Denaturation; Protein Folding; Protein Structure, Secondary; src Homology Domains; Thermodynamics	2009
Improved protein hydrogen/deuterium exchange mass spectrometry platform with fully automated data processing. Analytical chemistry, 2012, Jun-05, Volume: 84, Issue:11 Topics: Antibodies, Monoclonal; Automation, Laboratory; Deuterium; Deuterium Exchange Measurement; Guanidine; Hydrogen; Immunoglobulin G; Mass Spectrometry; Models, Chemical; Peptide Hydrolases; Peptides; Protein Conformation; Reference Standards; Software	2012
Role of a guanidinium cation-phosphodianion pair in stabilizing the vinyl carbanion intermediate of orotidine 5'-phosphate decarboxylase-catalyzed reactions. Biochemistry, 2013, Oct-22, Volume: 52, Issue:42 Topics: Crystallography, X-Ray; Decarboxylation; Deuterium; Guanidine; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Mutation; Orotidine-5'-Phosphate Decarboxylase; Protein Conformation; Ribonucleotides; Saccharomyces cerevisiae; Substrate Specificity; Uridine Monophosphate; Uridine Triphosphate	2013
Highly stereoselective recognition and deracemization of amino acids by supramolecular self-assembly. Angewandte Chemie (International ed. in English), 2014, Jan-13, Volume: 53, Issue:3 Topics: Aldehydes; Amino Acids; Crystallography, X-Ray; Deuterium; Guanidine; Molecular Conformation; Stereoisomerism	2014
Solid-State Hydrogen-Deuterium Exchange Mass Spectrometry (ssHDX-MS) of Lyophilized Poly-d,l-Alanine. Molecular pharmaceutics, 2019, 07-01, Volume: 16, Issue:7 Topics: Chemistry, Pharmaceutical; Deuterium; Drug Compounding; Excipients; Freeze Drying; Guanidine; Humidity; Hydrogen Deuterium Exchange-Mass Spectrometry; Kinetics; Mannitol; Models, Chemical; Peptides; Protein Structure, Secondary; Sodium Chloride; Sucrose; Trehalose	2019
The B domain of protein A retains residual structures in 6 M guanidinium chloride as revealed by hydrogen/deuterium-exchange NMR spectroscopy. Protein science : a publication of the Protein Society, 2023, Volume: 32, Issue:3 Topics: Deuterium; Guanidine; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Protein Denaturation; Protein Folding; Protons; Staphylococcal Protein A	2023