deuterium has been researched along with glutamic acid in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (10.71) | 18.7374 |
| 1990's | 15 (26.79) | 18.2507 |
| 2000's | 31 (55.36) | 29.6817 |
| 2010's | 4 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dvoráková, M; Kotyk, A | 1 |
| Rupitz, K; Trimbur, D; Warren, RA; Withers, SG | 1 |
| Choi, SY; Esaki, N; Soda, K; Yoshimura, T | 1 |
| Cuénod, M; Perschak, H | 1 |
| Esaki, N; Nakajima, N; Nakamura, K; Soda, K; Tanaka, H | 1 |
| Cook, PF | 1 |
| Azerad, R; Ducrocq, C; Fraisse, D; Tabet, JC | 1 |
| Azerad, R; Decottignies-Le Maréchal, P; Ducrocq, C; Marquet, A | 1 |
| Cerdán, S; Erhard, P; Moldes, M; Seelig, J | 1 |
| Gallo, KA; Knowles, JR; Tanner, ME | 2 |
| Burrin, DG; Frazer, EM; Henry, J; Jahoor, F; Reeds, PJ; Wykes, L | 1 |
| Daikhin, Y; Miller, SL; Yudkoff, M | 1 |
| Hübner, G; Kern, D; Kern, G; Killenberg-Jabs, M; Neef, H; Schneider, G; Tittmann, K; Wikner, C | 1 |
| Bailey, LB; Fisher, WP; Gregory, JF; Scott, KC; Stites, TE; Toth, JP | 1 |
| Overman, SA; Thomas, GJ | 1 |
| Green, EL; Klinman, JP; Plastino, J; Sanders-Loehr, J | 1 |
| Arata, Y; Ito, S; Kawaminami, S; Shimada, I; Takahashi, H | 1 |
| Christen, P; Graber, R; Mahon, MM; Malthouse, JP | 1 |
| Burks, EA; Cook, PF; Hwang, CC; Johnson, WH; Stanley, TM; Whitman, CP | 1 |
| Lee, JP; Zhang, S | 1 |
| Ferry, JG; Tripp, BC | 1 |
| Adelroth, P; Brzezinski, P; Gennis, RB; Gilderson, G; Karpefors, M; Tomson, FL | 1 |
| Blanchard, JS; Zheng, R | 1 |
| Makinen, MW; Mustafi, D; Sosa-Peinado, A | 1 |
| DeCicco, C; Nelson, D; Stein, RL; Thomas, B | 1 |
| Glavas, S; Tanner, ME | 1 |
| Epand, RF; Epand, RM; Martin, I; Ruysschaert, JM | 1 |
| Imamoto, Y; Kataoka, M; Kinoshita, T; Shirahige, Y; Tokunaga, F; Yoshihara, K | 1 |
| Bates, MA; Berry, A; Plater, AR; Thomson, GJ; Zgiby, S | 1 |
| Huong, NT; Inatomi, H; Yoshihashi, T | 1 |
| Freisleben, A; Rychlik, M; Schieberle, P | 1 |
| Ballou, DP; Madhavapeddi, P; Marsh, EN | 1 |
| Polgár, L; Sárkány, Z | 1 |
| Harrison, AG | 1 |
| Bolbach, G; Jensen, TR; Kjaer, K; Lahav, M; Leiserowitz, L; Shavit, E; Tang, M; Weissbuch, I; Zepik, H | 1 |
| BURRIS, RH; GRISOLIA, S | 1 |
| BLAKE, MI; LIN, SL; SIEGEL, FP | 1 |
| Boelens, R; Derix, NM; Hellingwerf, KJ; Kaptein, R; van der Horst, MA; van Nuland, NA; Wechselberger, RW | 1 |
| Ballou, DP; Marsh, EN; Xia, L | 1 |
| Bzymek, KP; Holz, RC | 1 |
| Brüschweiler, R; Zhang, F | 1 |
| Cheng, MC; Marsh, EN | 1 |
| Schofield, CJ; Sleeman, MC; Sorensen, JL | 1 |
| Scaraffia, PY; Wells, MA; Wysocki, VH; Zhang, Q | 1 |
| Hewlins, MJ; John, RA; Markova, M; Peneff, C; Schirmer, T | 1 |
| Deutz, NE; Engelen, MP; Rutten, EP; Schols, AM; Wouters, EF | 1 |
| Hellmer, H; Klimacek, M; Nidetzky, B | 1 |
| Gibson, KM; Jakobs, C; Struys, EA | 1 |
| Andersson, J; Barth, A; Hauser, K; Karjalainen, EL | 1 |
| Hansen, PE; Tomlinson, JH; Ullah, S; Williamson, MP | 1 |
| Ballesteros, P; Cerdán, S; Fonseca, LL; Rodrigues, TB; Sierra, A | 1 |
| Blakeley, MP; Chen, Y; Coates, L; Cooper, J; Tomanicek, SJ; Wang, KK; Weiss, KL | 1 |
| Greathouse, DV; Koeppe, RE; Rajagopalan, V | 1 |
| Palmer, DR; Vetter, ND | 1 |
| Irani, M; Jafari, S; Kazemi, N; Ryde, U | 1 |
56 other study(ies) available for deuterium and glutamic acid
| Article | Year |
|---|---|
Are proton symports in yeast directly linked to H(+)-ATPase acidification?
Topics: Deuterium; Diethylstilbestrol; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Leucine; Lysine; Membrane Potentials; Proton-Translocating ATPases; Protons; Saccharomyces cerevisiae; Suloctidil | 1992 |
Mechanistic consequences of mutation of the active site nucleophile Glu 358 in Agrobacterium beta-glucosidase.
Topics: Asparagine; Aspartic Acid; beta-Glucosidase; Binding Sites; Deuterium; Drug Stability; Glucosides; Glutamates; Glutamic Acid; Glutamine; Glycosylation; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Rhizobium; Structure-Activity Relationship | 1992 |
Reaction mechanism of glutamate racemase, a pyridoxal phosphate-independent amino acid racemase.
Topics: Amino Acid Isomerases; Bacterial Proteins; Cysteine; Deuterium; Enzyme Activation; Glutamates; Glutamic Acid; Kinetics; Magnetic Resonance Spectroscopy; Pediococcus; Pyridoxal Phosphate; Sulfhydryl Compounds; Tritium | 1992 |
In vivo release of endogenous glutamate and aspartate in the rat striatum during stimulation of the cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Deuterium; Electric Stimulation; Glutamates; Glutamic Acid; Kinetics; Leucine; Male; Rats; Rats, Inbred Strains | 1990 |
Enzymatic in situ analysis by 1H-NMR of the hydrogen transfer stereospecificity of NAD(P)+-dependent dehydrogenases.
Topics: Amino Acid Isomerases; Deuterium; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Hydrogen; Magnetic Resonance Spectroscopy; NADH, NADPH Oxidoreductases; NADP; NADPH Dehydrogenase; Stereoisomerism | 1989 |
Kinetic studies to determine the mechanism of regulation of bovine liver glutamate dehydrogenase by nucleotide effectors.
Topics: Adenosine Diphosphate; Animals; Binding, Competitive; Cattle; Deuterium; Dose-Response Relationship, Drug; Enzyme Activation; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Liver; NADP | 1982 |
An enzymatic method for the determination of enantiomeric composition and absolute configuration of deuterated or tritiated succinic acid.
Topics: Deuterium; Gas Chromatography-Mass Spectrometry; Glutamates; Glutamic Acid; Isocitrate Lyase; Isotope Labeling; Molecular Conformation; Oxo-Acid-Lyases; Stereoisomerism; Succinates; Succinic Acid; Tritium | 1984 |
The stereochemistry of hydrogen abstraction in vitamin K-dependent carboxylation.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Deuterium; Glutamates; Glutamic Acid; Hydrogen; Kinetics; Microsomes, Liver; Oligopeptides; Rats; Structure-Activity Relationship; Vitamin K; Vitamin K Deficiency | 1984 |
1H-2H exchange in the perfused rat liver metabolizing [3-13C]alanine and 2H2O as detected by multinuclear NMR spectroscopy.
Topics: Alanine; Animals; Aspartic Acid; Carbon Isotopes; Deuterium; Deuterium Oxide; Glutamic Acid; Hydrogen; Liver; Magnetic Resonance Spectroscopy; Male; Perfusion; Rats; Rats, Sprague-Dawley | 1994 |
Mechanism of the reaction catalyzed by glutamate racemase.
Topics: Amino Acid Isomerases; Cloning, Molecular; Deuterium; Deuterium Oxide; Escherichia coli; Glutamates; Glutamic Acid; Hydrogen; Isotope Labeling; Kinetics; Lactobacillus; Magnetic Resonance Spectroscopy; Oxygen Isotopes; Recombinant Proteins; Time Factors; Water | 1993 |
Isotope effects and the identification of catalytic residues in the reaction catalyzed by glutamate racemase.
Topics: Amino Acid Isomerases; Base Sequence; Cloning, Molecular; Deuterium; Deuterium Oxide; Escherichia coli; Glutamates; Glutamic Acid; Indicators and Reagents; Isotope Labeling; Kinetics; Lactobacillus; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Conformation; Radioisotope Dilution Technique; Recombinant Proteins; Time Factors; Water | 1993 |
Enteral glutamate is almost completely metabolized in first pass by the gastrointestinal tract of infant pigs.
Topics: Amino Acids; Animals; Carbon Isotopes; Deuterium; Enteral Nutrition; Glutamic Acid; Intestinal Absorption; Isotope Labeling; Kinetics; Phenylalanine; Radioisotope Dilution Technique; Swine; Time Factors | 1996 |
Metabolism of N-acetyl-L-aspartate in rat brain.
Topics: Animals; Aspartic Acid; Biotransformation; Brain; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Kinetics; Nitrogen Isotopes; Rats; Rats, Inbred F344; Time Factors | 1996 |
How thiamine diphosphate is activated in enzymes.
Topics: Allosteric Regulation; Binding Sites; Catalysis; Deuterium; Enzyme Activation; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Protons; Pyruvate Decarboxylase; Pyruvates; Thermodynamics; Thiamine Pyrophosphate; Transketolase | 1997 |
Kinetic modeling of folate metabolism through use of chronic administration of deuterium-labeled folic acid in men.
Topics: Adult; Chromatography, High Pressure Liquid; Deuterium; Eating; Folic Acid; Glutamic Acid; Humans; Male; Models, Biological; Nutritional Status | 1997 |
Raman markers of nonaromatic side chains in an alpha-helix assembly: Ala, Asp, Glu, Gly, Ile, Leu, Lys, Ser, and Val residues of phage fd subunits.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Deuterium; DNA, Single-Stranded; Glutamic Acid; Glycine; Inovirus; Isoleucine; Lysine; Molecular Sequence Data; Protein Structure, Secondary; Serine; Spectrum Analysis, Raman; Valine; Viral Proteins; Virus Assembly | 1999 |
An unexpected role for the active site base in cofactor orientation and flexibility in the copper amine oxidase from Hansenula polymorpha.
Topics: Amine Oxidase (Copper-Containing); Ammonia; Asparagine; Aspartic Acid; Binding Sites; Carbon; Deuterium; Enzyme Activation; Glutamic Acid; Hydrogen; Methylamines; Mutagenesis, Site-Directed; Oxygen; Pichia; Schiff Bases; Solvents; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Substrate Specificity; Viscosity | 1999 |
A multinuclear NMR study of the active site of an endoglucanase from a strain of Bacillus. Use of Trp residues as structural probes.
Topics: Amino Acid Sequence; Aspartic Acid; Bacillus; Binding Sites; Cellulase; Clostridium; Deuterium; Glutamic Acid; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Alignment; Tryptophan | 1999 |
The aspartate aminotransferase-catalysed exchange of the alpha-protons of aspartate and glutamate: the effects of the R386A and R292V mutations on this exchange reaction.
Topics: Aspartate Aminotransferases; Aspartic Acid; Deuterium; Glutamic Acid; Glycine Hydroxymethyltransferase; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mutation; Protons; Stereoisomerism; Tryptophan Synthase | 1999 |
Expression and stereochemical and isotope effect studies of active 4-oxalocrotonate decarboxylase.
Topics: Carbon Isotopes; Carboxy-Lyases; Deuterium; Enzyme Activation; Escherichia coli; Genetic Vectors; Glutamic Acid; Glutamine; Hydro-Lyases; Kinetics; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Protons; Pseudomonas putida; Recombinant Proteins; Stereoisomerism | 2000 |
Selectively 2H-labeled Glu/Asp: application to pKa measurements in Abeta amyloid peptides.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Aspartic Acid; Deuterium; Glutamic Acid; Histidine; Isotope Labeling; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptide Fragments; Protein Conformation | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Proton transfer from glutamate 286 determines the transition rates between oxygen intermediates in cytochrome c oxidase.
Topics: Deuterium; Electron Transport; Electron Transport Complex IV; Glutamic Acid; Mutation; Oxidation-Reduction; Oxygen; Photolysis; Protons; Rhodobacter sphaeroides | 2000 |
Identification of active site residues in E. coli ketopantoate reductase by mutagenesis and chemical rescue.
Topics: Acetic Acid; Alanine; Alcohol Oxidoreductases; Alkylation; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Cysteine; Deuterium; Escherichia coli; Formates; Gene Expression Regulation, Bacterial; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Pantothenic Acid; Recombinant Proteins; Sequence Alignment; Substrate Specificity | 2000 |
ENDOR structural characterization of a catalytically competent acylenzyme reaction intermediate of wild-type TEM-1 beta-lactamase confirms glutamate-166 as the base catalyst.
Topics: Acylation; Asparagine; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Catalysis; Deuterium; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Escherichia coli; Freezing; Glutamic Acid; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Penicillanic Acid; Penicillin G; Solvents; Spin Labels; Water | 2001 |
Slow-binding inhibition of gamma-glutamyl transpeptidase by gamma-boroGlu.
Topics: Acylation; Amides; Binding, Competitive; Boron Compounds; Boronic Acids; Catalysis; Coumarins; Deuterium; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Glutamic Acid; Glycine; Hydrolysis; Kinetics; Solvents | 2001 |
Active site residues of glutamate racemase.
Topics: Amino Acid Isomerases; Amino Acid Sequence; Asparagine; Aspartic Acid; Bacterial Proteins; Binding Sites; Deuterium; Glutamic Acid; Glutamine; Histidine; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Alignment | 2001 |
Membrane interactions of mutated forms of the influenza fusion peptide.
Topics: Alanine; Amino Acid Sequence; Deuterium; Glutamic Acid; Glycine; Hemagglutinin Glycoproteins, Influenza Virus; Kinetics; Lipid Bilayers; Membrane Fusion; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphorus Isotopes; Protein Conformation; Protein Structure, Secondary; Serine; Spectroscopy, Fourier Transform Infrared; Valine; Viral Fusion Proteins | 2001 |
Low-temperature Fourier transform infrared spectroscopy of photoactive yellow protein.
Topics: Bacterial Proteins; Coumaric Acids; Deuterium; Freezing; Glutamic Acid; Glutamine; Halorhodospira halophila; Light; Photochemistry; Photoreceptors, Microbial; Propionates; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 2001 |
A functional role for a flexible loop containing Glu182 in the class II fructose-1,6-bisphosphate aldolase from Escherichia coli.
Topics: Amino Acid Substitution; Binding Sites; Catalysis; Circular Dichroism; Deuterium; Dihydroxyacetone Phosphate; Escherichia coli; Fructose-Bisphosphate Aldolase; Glutamic Acid; Hydroxamic Acids; Kinetics; Models, Molecular; Oxidation-Reduction; Pliability; Protein Conformation; Protons; Structure-Activity Relationship; Zinc | 2002 |
Precursors of 2-acetyl-1-pyrroline, a potent flavor compound of an aromatic rice variety.
Topics: Carbon Isotopes; Deuterium; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Indicator Dilution Techniques; Nitrogen Isotopes; Ornithine; Oryza; Plant Leaves; Plant Structures; Proline; Pyrroles; Taste | 2002 |
Syntheses of labeled vitamers of folic acid to be used as internal standards in stable isotope dilution assays.
Topics: 4-Aminobenzoic Acid; Chromatography, High Pressure Liquid; Deuterium; Folic Acid; Glutamic Acid; Isotope Labeling; Leucovorin; Magnetic Resonance Spectroscopy; Pteridines; Pterins; Spectrometry, Mass, Electrospray Ionization; Tetrahydrofolates | 2002 |
Pre-steady-state kinetic studies on the Glu171Gln active site mutant of adenosylcobalamin-dependent glutamate mutase.
Topics: Amino Acid Substitution; Binding Sites; Cobamides; Deuterium; Escherichia coli Proteins; Glutamic Acid; Glutamine; Intramolecular Transferases; Kinetics; Mutagenesis, Site-Directed; N-Methylaspartate; Recombinant Proteins; Spectrophotometry, Ultraviolet; Substrate Specificity | 2002 |
The unusual catalytic triad of poliovirus protease 3C.
Topics: 3C Viral Proteases; Catalysis; Catalytic Domain; Cysteine; Cysteine Endopeptidases; Deuterium; Glutamic Acid; Glutamine; Glycine; Hydrogen-Ion Concentration; Kinetics; Methionine; Models, Chemical; Mutagenesis, Site-Directed; Poliovirus; Serine; Solvents; Substrate Specificity; Temperature; Thermodynamics; Viral Proteins | 2003 |
Fragmentation reactions of protonated peptides containing glutamine or glutamic acid.
Topics: Deuterium; Glutamic Acid; Glutamine; Oligopeptides; Protons; Spectrometry, Mass, Electrospray Ionization | 2003 |
Homochiral oligopeptides by chiral amplification within two-dimensional crystalline self-assemblies at the air-water interface; relevance to biomolecular handedness.
Topics: Air; Crystallization; Deuterium; Glutamic Acid; Lysine; Models, Molecular; Oligopeptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Surface Properties; Water; X-Ray Diffraction | 2003 |
Preparation of glutamate and carbamyl glutamate selectively labeled with deuterium.
Topics: Deuterium; Glutamates; Glutamic Acid; Humans | 1954 |
DEUTERIUM ISOTOPE EFFECTS IN NONENZYMATIC TRANSAMINATION OF L-GLUTAMIC ACID.
Topics: Amino Acids; Chromatography; Deuterium; Eukaryota; Glutamates; Glutamic Acid; Isotopes; Research | 1965 |
Lack of negative charge in the E46Q mutant of photoactive yellow protein prevents partial unfolding of the blue-shifted intermediate.
Topics: Amino Acid Substitution; Bacterial Proteins; Deuterium; Glutamic Acid; Glutamine; Halorhodospira halophila; Light; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Photochemistry; Photoreceptors, Microbial; Protein Folding; Protons | 2003 |
Role of Arg100 in the active site of adenosylcobalamin-dependent glutamate mutase.
Topics: Arginine; Bacterial Proteins; Binding Sites; Catalysis; Cobamides; Deuterium; Glutamic Acid; Hydrogen Bonding; Intramolecular Transferases; Kinetics; Lysine; Mutagenesis, Site-Directed; N-Methylaspartate; Spectrophotometry; Substrate Specificity; Vitamin B 12 | 2004 |
The catalytic role of glutamate 151 in the leucine aminopeptidase from Aeromonas proteolytica.
Topics: Aeromonas; Amino Acid Substitution; Aminopeptidases; Bacterial Proteins; Base Sequence; Catalytic Domain; Deuterium; DNA, Bacterial; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Leucyl Aminopeptidase; Metals; Mutagenesis, Site-Directed; Protons; Recombinant Proteins; Substrate Specificity; Thermodynamics | 2004 |
Spectral deconvolution of chemical mixtures by covariance NMR.
Topics: Amino Acids; Buffers; Deuterium; Glutamic Acid; Leucine; Magnetic Resonance Spectroscopy; Principal Component Analysis; Valine | 2004 |
Isotope effects for deuterium transfer between substrate and coenzyme in adenosylcobalamin-dependent glutamate mutase.
Topics: Catalysis; Chromatography, High Pressure Liquid; Cobamides; Deoxyadenosines; Deuterium; Deuterium Exchange Measurement; Energy Transfer; Escherichia coli Proteins; Free Radicals; Glutamic Acid; Holoenzymes; Hydrogen; Intramolecular Transferases; Kinetics; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity | 2005 |
Synthesis of deuterium labelled L- and D-glutamate semialdehydes and their evaluation as substrates for carboxymethylproline synthase (CarB)--implications for carbapenem biosynthesis.
Topics: Aldehydes; Carbapenems; Carbon-Carbon Lyases; Deuterium; Glutamic Acid; Isotope Labeling; Molecular Structure; Stereoisomerism | 2005 |
Fragmentation pathway for glutamine identification: loss of 73 Da from dimethylformamidine glutamine isobutyl ester.
Topics: Butanols; Deuterium; Dimethylformamide; Glutamic Acid; Glutamine; Spectrometry, Mass, Electrospray Ionization | 2005 |
Determinants of substrate specificity in omega-aminotransferases.
Topics: Amino Acids; Aminobutyrates; Binding Sites; Biochemistry; Crystallography, X-Ray; Deuterium; DNA; Glutamic Acid; Humans; Isoleucine; Ketoglutaric Acids; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Protein Binding; Pyridoxal Phosphate; Recombinant Fusion Proteins; Spectrophotometry; Substrate Specificity; Time Factors; Transaminases; Tyrosine | 2005 |
Metabolic effects of glutamine and glutamate ingestion in healthy subjects and in persons with chronic obstructive pulmonary disease.
Topics: Aged; Amino Acids; Case-Control Studies; Deuterium; Dietary Supplements; Glutamic Acid; Glutamine; Health Status; Humans; Male; Middle Aged; Muscle, Skeletal; Postprandial Period; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests | 2006 |
Catalytic mechanism of Zn2+-dependent polyol dehydrogenases: kinetic comparison of sheep liver sorbitol dehydrogenase with wild-type and Glu154-->Cys forms of yeast xylitol dehydrogenase.
Topics: Animals; Cysteine; D-Xylulose Reductase; Deuterium; Enzyme Inhibitors; Fungal Proteins; Glutamic Acid; Humans; Hydrogen-Ion Concentration; L-Iditol 2-Dehydrogenase; Liver; Molecular Structure; NAD; Oxidation-Reduction; Point Mutation; Sheep; Solvents; Sorbitol; Zinc | 2007 |
Novel insights into L-2-hydroxyglutaric aciduria: mass isotopomer studies reveal 2-oxoglutaric acid as the metabolic precursor of L-2-hydroxyglutaric acid.
Topics: Alcohol Oxidoreductases; Carbon Isotopes; Cell Line; Citric Acid; Deuterium; Gas Chromatography-Mass Spectrometry; Glucose; Glutamic Acid; Glutarates; Humans; Ketoglutaric Acids; Lymphocytes; Metabolism, Inborn Errors; Oxidation-Reduction | 2007 |
Protonation and hydrogen bonding of Ca2+ site residues in the E2P phosphoenzyme intermediate of sarcoplasmic reticulum Ca2+-ATPase studied by a combination of infrared spectroscopy and electrostatic calculations.
Topics: Animals; Aspartic Acid; Calcium; Deuterium; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Ligands; Protein Conformation; Protons; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spectrophotometry, Infrared; Static Electricity; Water | 2008 |
Characterization of salt bridges to lysines in the protein G B1 domain.
Topics: Aspartic Acid; Bacterial Proteins; Deuterium; Escherichia coli; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Nerve Tissue Proteins; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; Quantum Theory; Salts; Streptococcus | 2009 |
The turnover of the H3 deuterons from (2-13C) glutamate and (2-13C) glutamine reveals subcellular trafficking in the brain of partially deuterated rats.
Topics: Acetates; Aconitate Hydratase; Algorithms; Animals; Brain; Brain Chemistry; Carbon Isotopes; Cytosol; Deuterium; Glucose; Glutamic Acid; Glutamine; Hydrogen; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Male; Mitochondria; Models, Statistical; Rats; Rats, Wistar; Subcellular Fractions | 2009 |
The active site protonation states of perdeuterated Toho-1 β-lactamase determined by neutron diffraction support a role for Glu166 as the general base in acylation.
Topics: Acylation; beta-Lactamases; Catalytic Domain; Deuterium; Glutamic Acid; Hydrogen Bonding; Mutant Proteins; Mutation, Missense; Neutron Diffraction | 2011 |
Influence of glutamic acid residues and pH on the properties of transmembrane helices.
Topics: Alanine; Amino Acid Sequence; Animals; Deuterium; Glutamic Acid; Hydrogen-Ion Concentration; Lipid Bilayers; Membrane Proteins; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary | 2017 |
Simultaneous Measurement of Glucose-6-phosphate 3-Dehydrogenase (NtdC) Catalysis and the Nonenzymatic Reaction of Its Product: Kinetics and Isotope Effects on the First Step in Kanosamine Biosynthesis.
Topics: Bacillus subtilis; Bacterial Proteins; Biocatalysis; Deuterium; Escherichia coli; Gene Expression Regulation, Bacterial; Glucosamine; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; NAD; Operon; Oxidation-Reduction; Protons; Recombinant Proteins; Thermodynamics | 2017 |
Higher Flexibility of Glu-172 Explains the Unusual Stereospecificity of Glyoxalase I.
Topics: Deuterium; Glutamic Acid; Lactoylglutathione Lyase; Molecular Dynamics Simulation; Molecular Structure; Protons; Quantum Theory; Stereoisomerism; Substrate Specificity | 2018 |