deuterium has been researched along with folic acid in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (40.00) | 18.7374 |
| 1990's | 8 (26.67) | 18.2507 |
| 2000's | 6 (20.00) | 29.6817 |
| 2010's | 4 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bailey, LB; Cerda, JJ; Curry, SH; Gregory, JF; Toth, JP; von der Porten, AE | 1 |
| Bailey, LB; Baumgartner, TG; Bhandari, SD; Cerda, JJ; Gregory, JF; Toth, JP | 1 |
| Morrison, JF; Stone, SR | 2 |
| Benkovic, SJ; Chen, JT; Taira, K; Tu, CP | 1 |
| Gregory, JF; Toth, JP | 1 |
| Zakrzewski, S | 1 |
| Pastore, EJ | 2 |
| Brewer, CF; Santi, DV | 1 |
| Dunlap, RB; Ellis, PD; Lyon, JA | 1 |
| Poe, M | 1 |
| Ghambeer, RK; Ljungdahl, LG; Parker, DJ; Wood, HG | 1 |
| Baugh, CM; Matthews, RG | 1 |
| Bailey, LB; Gregory, JF; Kownacki-Brown, PA; Toth, JP; Wang, C | 1 |
| Bailey, LB; Fisher, WP; Gregory, JF; Scott, KC; Stites, TE; Toth, JP | 1 |
| Bailey, LB; Gregory, JF; Toth, JP; Wei, MM | 1 |
| Gregory, JF; Pfeiffer, CM | 1 |
| Bailey, LB; Gregory, JF; Pfeiffer, CM; Rogers, LM | 1 |
| Bailey, LB; Gregory, JF; Toth, JP; Williamson, J | 1 |
| Finglas, PM; Maunder, P; Mellon, FA; Ridge, B; Southon, S; Vahteristo, L; Witthöft, CM; Wright, AJ | 1 |
| Freisleben, A; Rychlik, M; Schieberle, P | 1 |
| Gao, J; Garcia-Viloca, M; Truhlar, DG | 1 |
| Dyson, HJ; Schnell, JR; Wright, PE | 1 |
| Mayr, A; Rychlik, M | 1 |
| Birdsall, B; Feeney, J; Polshakov, VI | 1 |
| Mönch, S; Rychlik, M | 1 |
| Büttner, BE; Köhler, P; Ohrvik, VE; Rychlik, M; Witthöft, CM | 1 |
| Frank, T; Mönch, S; Netzel, G; Netzel, M; Ott, U; Rychlik, M | 1 |
| Koehler, P; Kopp, M; Morisset, R; Rychlik, M | 1 |
3 trial(s) available for deuterium and folic acid
| Article | Year |
|---|---|
Bioavailability for humans of deuterium-labeled monoglutamyl and polyglutamyl folates is affected by selected foods.
Topics: Administration, Oral; Adult; Biological Availability; Deuterium; Diet; Folic Acid; Humans; Male; Pteroylpolyglutamic Acids | 1996 |
A dual-label stable-isotopic protocol is suitable for determination of folate bioavailability in humans: evaluation of urinary excretion and plasma folate kinetics of intravenous and oral doses of [13C5] and [2H2]folic acid.
Topics: Administration, Oral; Adult; Biological Availability; Carbon Isotopes; Deuterium; Female; Folic Acid; Humans; Injections, Intravenous; Isotope Labeling; Male | 1997 |
Folate bioavailability from foods rich in folates assessed in a short term human study using stable isotope dilution assays.
Topics: Adult; Cheese; Cross-Over Studies; Deuterium; Diet, Fat-Restricted; Dietary Supplements; Female; Folic Acid; Frozen Foods; Germany; Germination; Humans; Indicator Dilution Techniques; Male; Models, Biological; Nutritive Value; Plant Leaves; Seeds; Spinacia oleracea; Tetrahydrofolates; Triticum; Young Adult | 2015 |
27 other study(ies) available for deuterium and folic acid
| Article | Year |
|---|---|
In vivo folate kinetics during chronic supplementation of human subjects with deuterium-labeled folic acid.
Topics: Adult; Chromatography, High Pressure Liquid; Deuterium; Erythrocytes; Folic Acid; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Male | 1992 |
Relative bioavailability of deuterium-labeled monoglutamyl and hexaglutamyl folates in human subjects.
Topics: Administration, Oral; Adult; Biological Availability; Deuterium; Folic Acid; Gas Chromatography-Mass Spectrometry; Humans; Injections, Intravenous; Male; Pteroylpolyglutamic Acids; Regression Analysis | 1991 |
Dihydrofolate reductase from Escherichia coli: the kinetic mechanism with NADPH and reduced acetylpyridine adenine dinucleotide phosphate as substrates.
Topics: Deuterium; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Tetrahydrofolate Dehydrogenase; Viscosity | 1988 |
Mechanism of the reaction catalyzed by dihydrofolate reductase from Escherichia coli: pH and deuterium isotope effects with NADPH as the variable substrate.
Topics: Aspartic Acid; Deuterium; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; NADP; Solvents; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 1988 |
Probing the functional role of phenylalanine-31 of Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
Topics: Amino Acids; Binding Sites; Deuterium; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Mutation; NADP; Phenylalanine; Plasmids; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tyrosine; Valine | 1987 |
Chemical synthesis of deuterated folate monoglutamate and in vivo assessment of urinary excretion of deuterated folates in man.
Topics: Administration, Oral; Adult; Chromatography, Affinity; Chromatography, High Pressure Liquid; Deuterium; Folic Acid; Gas Chromatography-Mass Spectrometry; Humans; Isotope Labeling; Magnetic Resonance Spectroscopy; Male | 1988 |
On the mechanism of chemical and enzymatic reduction of folate and dihydrofolate.
Topics: Chemical Phenomena; Chemistry; Deuterium; Folic Acid; NADP; Pteridines; Tetrahydrofolate Dehydrogenase; Tritium | 1966 |
Proton magnetic resonance studies of folate and folate antagonists.
Topics: Aminopterin; Chemical Phenomena; Chemistry; Deuterium; Folic Acid; Folic Acid Antagonists; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methotrexate; NADP; Structure-Activity Relationship; Temperature | 1971 |
Model studies of thymidylate synthetase. Intramolecular catalysis of 5-hydrogen exchange and 5-hydroxymethylation of 1-substituted uracils.
Topics: Acetals; Carbon Isotopes; Catalysis; Chromatography, Paper; Chromatography, Thin Layer; Deoxyuridine; Deuterium; Ethers, Cyclic; Folic Acid; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Models, Chemical; Protons; Pyrimidinones; Ribonucleosides; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Thymidylate Synthase; Tritium; Uracil; Uridine | 1973 |
Assignment of the carbon-13 nuclear magnetic resonance spectrum of folic acid.
Topics: Aminobenzoates; Benzamides; Carbon Isotopes; Chemical Phenomena; Chemistry; Deuterium; Folic Acid; Glutamates; Magnetic Resonance Spectroscopy; Protons; Pteridines; Purines; Quinazolines; Quinoxalines; Ribonucleosides | 1973 |
Proton magnetic resonance studies of folate, dihydrofolate, and methotrexate. Evidence from pH and concentration studies for dimerization.
Topics: Aminopterin; Carboxylic Acids; Chemical Phenomena; Chemistry; Deuterium; Folic Acid; Hydrogen-Ion Concentration; Macromolecular Substances; Magnetic Resonance Spectroscopy; Mathematics; Methotrexate; Models, Structural; Osmolar Concentration; Protons; Pterins; Spectrophotometry, Ultraviolet | 1973 |
Total synthesis of acetate from carbon dioxide. Retention of deuterium during carboxylation of trideuteriomethyltetrahydrofolate or trideuteriomethylcobalamin.
Topics: Acetates; Carbon Dioxide; Carbon Isotopes; Catalysis; Clostridium; Cobamides; Coenzymes; Deuterium; Folic Acid; Kinetics; Ligases; Mass Spectrometry; Models, Chemical; Vitamin B 12 | 1972 |
Interactions of pig liver methylenetetrahydrofolate reductase with methylenetetrahydropteroylpolyglutamate substrates and with dihydropteroylpolyglutamate inhibitors.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alcohol Oxidoreductases; Animals; Deuterium; Folic Acid; Kinetics; Liver; Pteroylpolyglutamic Acids; Solvents; Structure-Activity Relationship; Swine; Tetrahydrofolates | 1980 |
Folate and its reduced forms labeled with deuterium at carbon-7.
Topics: Deuterium; Folic Acid; Isotope Labeling | 1980 |
Urinary excretion of deuterium-labeled folate and the metabolite p-aminobenzoylglutamate in humans.
Topics: Adult; Chromatography, High Pressure Liquid; Deuterium; Folic Acid; Gas Chromatography-Mass Spectrometry; Glutamates; Humans; Male | 1993 |
Kinetic modeling of folate metabolism through use of chronic administration of deuterium-labeled folic acid in men.
Topics: Adult; Chromatography, High Pressure Liquid; Deuterium; Eating; Folic Acid; Glutamic Acid; Humans; Male; Models, Biological; Nutritional Status | 1997 |
Preparation of stable isotopically labeled folates for in vivo investigation of folate absorption and metabolism.
Topics: Deuterium; Folic Acid; Gas Chromatography-Mass Spectrometry; Glutamates; Humans; Intestinal Absorption; Isotope Labeling; Molecular Structure; Pteroylpolyglutamic Acids | 1997 |
Urinary excretion of [2H4]folate by nonpregnant women following a single oral dose of [2H4]folic acid is a functional index of folate nutritional status.
Topics: Adult; Deuterium; Dietary Supplements; Erythrocytes; Female; Folic Acid; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Kinetics; Nutritional Status | 1998 |
Use of an oral/intravenous dual-label stable-isotope protocol to determine folic acid bioavailability from fortified cereal grain foods in women.
Topics: Absorption; Administration, Oral; Adult; Biological Availability; Carbon Isotopes; Deuterium; Edible Grain; Female; Folic Acid; Food, Fortified; Humans; Injections, Intravenous; Isotope Labeling | 2002 |
Syntheses of labeled vitamers of folic acid to be used as internal standards in stable isotope dilution assays.
Topics: 4-Aminobenzoic Acid; Chromatography, High Pressure Liquid; Deuterium; Folic Acid; Glutamic Acid; Isotope Labeling; Leucovorin; Magnetic Resonance Spectroscopy; Pteridines; Pterins; Spectrometry, Mass, Electrospray Ionization; Tetrahydrofolates | 2002 |
Reaction-path energetics and kinetics of the hydride transfer reaction catalyzed by dihydrofolate reductase.
Topics: Amino Acids; Binding Sites; Catalysis; Computer Simulation; Deuterium; Folic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; NADP; Quantum Theory; Tetrahydrofolate Dehydrogenase; Thermodynamics | 2003 |
Effect of cofactor binding and loop conformation on side chain methyl dynamics in dihydrofolate reductase.
Topics: Binding Sites; Deuterium; Escherichia coli Proteins; Folic Acid; Isoleucine; NADP; Nanotechnology; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Structure, Tertiary; Spectrophotometry; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Thermodynamics; Threonine; Valine | 2004 |
Quantitation of N2-[1-(1-carboxy)ethyl]folic acid, a nonenzymatic glycation product of folic acid, in fortified foods and model cookies by a Stable isotope dilution assay.
Topics: Deuterium; Drug Stability; Folic Acid; Food Analysis; Food, Fortified; Glycosylation; Indicator Dilution Techniques; Mass Spectrometry | 2005 |
Effects of co-operative ligand binding on protein amide NH hydrogen exchange.
Topics: Amides; Bacterial Proteins; Deuterium; Folic Acid; Hydrogen; Hydrogen-Ion Concentration; Lacticaseibacillus casei; Ligands; Models, Molecular; NADP; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Temperature; Tetrahydrofolate Dehydrogenase; Thermodynamics; Trimethoprim | 2006 |
Improved folate extraction and tracing deconjugation efficiency by dual label isotope dilution assays in foods.
Topics: Carbon Isotopes; Deuterium; Folic Acid; Food Analysis; Indicator Dilution Techniques; Isotope Labeling; Pteroylpolyglutamic Acids | 2012 |
Quantification of isotope-labeled and unlabeled folates and folate catabolites in urine samples by stable isotope dilution assay.
Topics: Carbon Isotopes; Deuterium; Folic Acid; Glutamates; Humans; Isotope Labeling; Magnetic Resonance Spectroscopy; Mass Spectrometry; para-Aminobenzoates | 2013 |
Stable Isotope Dilution Assays for Clinical Analyses of Folates and Other One-Carbon Metabolites: Application to Folate-Deficiency Studies.
Topics: Animals; Chickens; Deuterium; Folic Acid; Folic Acid Deficiency; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 2016 |