Compounds > deuterium
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deuterium and dihydrofolate

deuterium has been researched along with dihydrofolate in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morrison, JF; Stone, SR2
Benkovic, SJ; Chen, JT; Taira, K; Tu, CP1
Pastore, EJ1
Gao, J; Garcia-Viloca, M; Truhlar, DG1

Other Studies

5 other study(ies) available for deuterium and dihydrofolate

ArticleYear
Dihydrofolate reductase from Escherichia coli: the kinetic mechanism with NADPH and reduced acetylpyridine adenine dinucleotide phosphate as substrates.
    Biochemistry, 1988, Jul-26, Volume: 27, Issue:15

    Topics: Deuterium; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Tetrahydrofolate Dehydrogenase; Viscosity

1988
Mechanism of the reaction catalyzed by dihydrofolate reductase from Escherichia coli: pH and deuterium isotope effects with NADPH as the variable substrate.
    Biochemistry, 1988, Jul-26, Volume: 27, Issue:15

    Topics: Aspartic Acid; Deuterium; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; NADP; Solvents; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase

1988
Probing the functional role of phenylalanine-31 of Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
    Biochemistry, 1987, Jun-30, Volume: 26, Issue:13

    Topics: Amino Acids; Binding Sites; Deuterium; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Mutation; NADP; Phenylalanine; Plasmids; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tyrosine; Valine

1987
Folate and its reduced forms labeled with deuterium at carbon-7.
    Methods in enzymology, 1980, Volume: 66

    Topics: Deuterium; Folic Acid; Isotope Labeling

1980
Reaction-path energetics and kinetics of the hydride transfer reaction catalyzed by dihydrofolate reductase.
    Biochemistry, 2003, Nov-25, Volume: 42, Issue:46

    Topics: Amino Acids; Binding Sites; Catalysis; Computer Simulation; Deuterium; Folic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; NADP; Quantum Theory; Tetrahydrofolate Dehydrogenase; Thermodynamics

2003