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deuterium and cysteine

deuterium has been researched along with cysteine in 97 studies

Research

Studies (97)

TimeframeStudies, this research(%)All Research%
pre-199032 (32.99)18.7374
1990's23 (23.71)18.2507
2000's32 (32.99)29.6817
2010's10 (10.31)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, BM; Chan, JK1
Finley, JW; Friedman, M; Snow, JT1
Krishna, G; Pohl, LR1
Hruby, VJ; Upson, DA1
Choi, SY; Esaki, N; Soda, K; Yoshimura, T1
Anders, MW; Fitzsimmons, ME; Harris, JW1
Arakawa, T; Prestrelski, SJ1
Commandeur, JN; Stijntjes, GJ; Vermeulen, NP; Wijngaard, J1
Gaskell, SJ; Orkiszewski, RS; Raftery, MJ; Thorne, GC1
Davidson, VL; Husain, M; Loehr, TM; Sanders-Loehr, J; Sharma, KD1
Kiick, DM; Phillips, RS2
Miller, JN1
Bowman, M; Kevan, L; Kimura, T; Mukai, K1
Haerlin, R; Lingens, F; Süssmuth, R1
Hayatsu, H; Kawazoe, Y; Wataya, Y2
Polgár, L1
Choi, Y; Kumagai, H; Sejima, S; Yamada, H1
Fukami, H; Kumagai, H; Ohkishi, H; Ueno, T; Yamada, H1
Palmer, G; Salmeen, I1
Flavin, M; Posner, BI1
Stapleton, IW; Weber, OA1
Bender, ML; Polgár, L1
Steiner, RF; Weinryb, I1
Barker, HA; Chirpich, TP; Costilow, RN; Zappia, V1
Adams, E; Finlay, TH1
Blake, MI; Carlstedt, BC; Crespi, HL; Katz, JJ1
Banks, TE; Shafer, JA1
Huc, C; Olomucki, A1
Cohen, SG; Lam, FL1
Flavin, M; Guggenheim, S1
White, RH1
Anders, MW; Stevens, JL1
Creighton, DJ; Wandinger, A1
Frey, PA; Lieder, KW; Reed, GH; Wu, W1
Gloss, LM; Kirsch, JF1
Kozarich, JW; Magliozzo, RS; Parast, CV; Peisach, J; Wong, KK1
Cheng, H; Markley, JL; Oh, BH; Westler, WM; Xia, B1
Kozarich, JW; Lewisch, SA; Magliozzo, RS; Parast, CV; Peisach, J; Wong, KK1
Deutsch, JC; Hassell, KL; Kolhouse, JC; Kolhouse, JF; Santhosh-Kumar, CR1
Chapman, TE; Cortiella, J; Fukagawa, NK; Hiramatsu, T; Marchini, JS; Young, VR; Yu, YM1
Bhatnagar, A; Chakrabarti, B; Liu, SQ; Srivastava, SK; Ueno, N1
Ator, M; Bollinger, JM; McCraken, J; Peisach, J; Robins, MJ; Salowe, S; Samano, MC; Stubbe, J1
Arp, DJ; Sayavedra-Soto, LA1
Gaggelli, E; Grzonka, Z; Kasprzykowski, F; Kozlowski, H; Maccotta, A; Valensin, G1
Laity, JH; Lester, CC; Montelione, GT; Scheraga, HA; Shimotakahara, S; Zimmerman, DE1
Aumelas, A; Calas, B; Chavanieu, A; Chiche, L; Grassy, G; Roch, P; Vignal, E1
Cook, PF; Kim, SK; Kredich, NM; Nalabolu, SR; Rege, VD; Schnackerz, KD; Tai, CH; Yoon, MY1
Emmett, MR; Hendrickson, CL; Li, W; Marshall, AG; Wang, F; Wu, L; Zhang, YL; Zhang, ZY1
Digits, JA; Hedstrom, L1
Glavas, S; Tanner, ME1
Akhtar, M; Botting, NP; Gani, D; Lasry, P; Neal, T; Pollard, JR; Richardson, S1
Jenk, D; LeMaster, DM; Markley, JL; Westler, WM; Xia, B1
Ferry, JG; Tripp, BC1
Crowder, MW; Taylor, RA; Yanchak, MP1
Campbell, SJ; Dempsey, CE; Lamble, NV; Sessions, RB1
Blanchard, JS; Zheng, R1
Astashkin, AV; Cosper, MM; Enemark, JH; Raitsimring, AM1
Bansho, Y; Inoue, S; Ito, K; Kawanishi, S; Midorikawa, K; Murata, M; Ohnishi, S1
Deinzer, ML; Ho, PS; Kim, MY; Maier, CS; Reed, DJ1
Cammack, R; Hatchikian, C; Hüttermann, J; Kappl, R; Müller, A; Tscherny, I1
Deinzer, ML; Schimerlik, MI; Watson, J; Yan, X; Zhang, H1
Deinzer, ML; Maier, CS; Schimerlik, MI; Yan, X; Zhang, YH1
Polgár, L; Sárkány, Z1
Ball, RO; Cole, DE; Di Buono, M; Pencharz, PB; Wykes, LJ1
Aviles, FX; Bronsoms, S; Canals, F; Querol, E; Villanueva, J1
RITTENBERG, D; SADANA, JC1
Dingley, AJ; Grötzinger, J; Ozbek, S; Rose-John, S; Schwantner, A1
Citterio, A; Lapadula, M; Righetti, PG; Sebastiano, R1
Gleason, KJ; Hanna, PE; Vath, GM; Wagner, CR; Wang, H1
Darmaun, D; Mauras, N; Sager, BK; Smith, SD; Sweeten, S; Welch, S1
Hong, E; Kang, SW; Lee, W; Shin, J; Tanaka, T1
Carmieli, R; Goldfarb, D; Papo, N; Potapov, A; Shai, Y; Zimmermann, H1
Bindila, L; Cepo, T; Cindrić, M; Skrlin, A; Vuletić, M1
Breuillé, D; Buffière, C; Gimonet, J; Mercier, S; Mirand, PP; Obled, C; Papet, I1
Cemazar, M; Craik, DJ; Daly, NL; Häggblad, S; Lo, KP; Yulyaningsih, E1
Coram, M; Faca, V; Fitzgibbon, M; Glukhova, V; Hanash, S; McIntosh, M; Phanstiel, D; Zhang, Q1
Bindila, L; Cepo, T; Cindrić, M; Peter-Katalinić, J1
Hellmer, H; Klimacek, M; Nidetzky, B1
Kass, SR; Pawlow, A; Poutsma, JC; Tian, Z1
Blindauer, CA; Leszczyszyn, OI; Schmid, R1
Guo, YL; Zhang, J; Zhang, L; Zhou, Y1
Day, AE; King, SB; Nelson, KJ; Poole, LB; Zeng, BB1
Buettner, H; Frey, U; Luisier, JL; Rausis, T; Völker, S1
Lam, AK; O'Hair, RA; Ryzhov, V1
Jee, J; Kainosho, M; Takeda, M; Terauchi, T1
Angerer, J; Hartmann, EC; Koch, HM; Latzin, JM; Schindler, BK1
Aldous, KM; Dailey, M; Fasco, MJ; Hauer, CR; Lu, S; Schneider, E; Stack, RF1
Amano, M; Fukui, K; Hasegawa, J; Kishi, N; Kobayashi, N; Nakazawa, T; Uchiyama, S1
Kainosho, M; Takeda, M; Terauchi, T1
Kellermann, J; Lottspeich, F1
Arntzen, MØ; de Souza, GA; Koehler, CJ; Thiede, B1
Morris, AJ; Onono, FO; Spielmann, HP; Subramanian, KL; Subramanian, T; Sunkara, M1
Mozziconacci, O; Schöneich, C1
Du, Q; Schramm, VL; Wang, Z1

Trials

2 trial(s) available for deuterium and cysteine

ArticleYear
Methionine and cysteine kinetics at different intakes of cystine in healthy adult men.
    The American journal of clinical nutrition, 1994, Volume: 60, Issue:4

    Topics: Adult; Carbon Isotopes; Cysteine; Cystine; Deuterium; Dietary Proteins; Humans; Infusions, Intravenous; Kinetics; Male; Methionine; Oxidation-Reduction

1994
Regulation of sulfur amino acid metabolism in men in response to changes in sulfur amino acid intakes.
    The Journal of nutrition, 2003, Volume: 133, Issue:3

    Topics: Adult; Amino Acids, Sulfur; Carbon Isotopes; Cross-Over Studies; Cysteine; Deuterium; Diet; Dietary Proteins; Homocysteine; Humans; Kinetics; Male; Methionine; Methylation; Nutritional Requirements

2003

Other Studies

95 other study(ies) available for deuterium and cysteine

ArticleYear
Conformation of Escherichia coli glutamic acid tRNA II as studied by hydrogen-tritium exchange catalyzed by cysteine methyl ester.
    European journal of biochemistry, 1976, Apr-15, Volume: 64, Issue:1

    Topics: Base Sequence; Binding Sites; Cysteine; Deuterium; DNA; Escherichia coli; Glutamates; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Nucleic Acid Denaturation; RNA, Bacterial; RNA, Transfer; Tritium

1976
A novel diazonium-sulfhydryl reaction in the inactivation of yeast alcohol dehydrogenase by diazotized 3-aminopyridine adenine dinucleotide.
    The Journal of biological chemistry, 1975, Jan-10, Volume: 250, Issue:1

    Topics: Alcohol Oxidoreductases; Amino Acids; Azo Compounds; Benzoates; Binding Sites; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; Deuterium; Disulfides; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; NAD; Nitro Compounds; Protein Binding; Saccharomyces cerevisiae; Spectrophotometry; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Time Factors

1975
Oxidation of sulfhydryl groups to disulfides by sulfoxides.
    Biochemical and biophysical research communications, 1975, May-05, Volume: 64, Issue:1

    Topics: Chemical Phenomena; Chemistry; Cysteine; Deuterium; Disulfides; Glutathione; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Penicillamine; Sulfhydryl Compounds; Sulfoxides; Valine

1975
Deuterium isotope effect in bioactivation and hepatotoxicity of chloroform.
    Life sciences, 1978, Sep-11, Volume: 23, Issue:10

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Cysteine; Cytochrome P-450 Enzyme System; Deuterium; Male; Microsomes, Liver; Phenobarbital; Rats; Thiazoles

1978
Synthesis of specifically deuterated S-benzylcysteines and of oxytocin and related diastereomers deuterated in the half-cystine positions.
    The Journal of organic chemistry, 1976, Apr-16, Volume: 41, Issue:8

    Topics: Benzyl Compounds; Chemical Phenomena; Chemistry; Cysteine; Deuterium; Isotope Labeling; Methods; Oxytocin; Stereoisomerism

1976
Reaction mechanism of glutamate racemase, a pyridoxal phosphate-independent amino acid racemase.
    Journal of biochemistry, 1992, Volume: 112, Issue:1

    Topics: Amino Acid Isomerases; Bacterial Proteins; Cysteine; Deuterium; Enzyme Activation; Glutamates; Glutamic Acid; Kinetics; Magnetic Resonance Spectroscopy; Pediococcus; Pyridoxal Phosphate; Sulfhydryl Compounds; Tritium

1992
Synthesis of [2-3H-ethyl]S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine and its use in covalent-binding studies.
    Analytical biochemistry, 1992, Aug-01, Volume: 204, Issue:2

    Topics: Animals; Cysteine; Cytosol; Deuterium; Kidney; Liver; Lysine; Magnetic Resonance Spectroscopy; Microsomes; Mitochondria; Rats; Rats, Inbred F344; Tritium

1992
The solution structure and conformational dynamics of tumor necrosis factor-alpha and a (Cys69----Asp; Cys101----Arg) analog as examined by IR spectroscopy and hydrogen exchange.
    Protein engineering, 1991, Volume: 4, Issue:7

    Topics: Animals; Arginine; Aspartic Acid; Cysteine; Deuterium; Hydrogen; Mutagenesis, Site-Directed; Protein Conformation; Spectrophotometry, Infrared; Tumor Necrosis Factor-alpha

1991
Metabolism of L-cysteine S-conjugates and N-(trideuteroacetyl)-L-cysteine S-conjugates of four fluoroethylenes in the rat. Role of balance of deacetylation and acetylation in relation to the nephrotoxicity of mercapturic acids.
    Biochemical pharmacology, 1991, Jun-21, Volume: 42, Issue:1

    Topics: Acetylation; Acetylcysteine; Amidohydrolases; Animals; Arylamine N-Acetyltransferase; Bile; Chlorofluorocarbons; Cysteine; Deuterium; Ethylenes; Gas Chromatography-Mass Spectrometry; Hydrocarbons, Fluorinated; Hydrocarbons, Halogenated; Kidney; Kidney Diseases; Liver; Male; Rats; Rats, Inbred Strains; Subcellular Fractions

1991
Preparation and tandem mass spectrometric analyses of deuterium-labeled cysteine-containing leukotrienes.
    Biomedical & environmental mass spectrometry, 1990, Volume: 19, Issue:8

    Topics: Cysteine; Deuterium; Indicators and Reagents; Isotope Labeling; Mass Spectrometry; SRS-A

1990
Resonance Raman spectroscopy of amicyanin, a blue copper protein from Paracoccus denitrificans.
    The Journal of biological chemistry, 1988, Mar-05, Volume: 263, Issue:7

    Topics: Azurin; Bacterial Proteins; Binding Sites; Copper; Cysteine; Deuterium; Electron Spin Resonance Spectroscopy; Metalloproteins; Paracoccus denitrificans; Plastocyanin; Spectrum Analysis, Raman

1988
Mechanistic deductions from multiple kinetic and solvent deuterium isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Escherichia coli tryptophan indole-lyase.
    Biochemistry, 1988, Sep-20, Volume: 27, Issue:19

    Topics: Alanine; Binding, Competitive; Catalysis; Cysteine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lyases; Oxindoles; Pyridoxal Phosphate; Solvents; Tryptophan; Tryptophanase

1988
Mechanistic deductions from kinetic isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Erwinia herbicola and Citrobacter freundii tyrosine phenol-lyase.
    Biochemistry, 1988, Sep-20, Volume: 27, Issue:19

    Topics: Alanine; Binding, Competitive; Citrobacter; Cysteine; Deuterium; Erwinia; Hydrogen-Ion Concentration; Kinetics; Lyases; Phenylalanine; Pyridoxal Phosphate; Tyrosine; Tyrosine Phenol-Lyase

1988
Studies on Waldenström macroglobulins. 3. The conformation of immunoglobulin M investigated by infrared spectroscopy.
    Biochimica et biophysica acta, 1971, Jun-29, Volume: 236, Issue:3

    Topics: Amides; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Cysteine; Detergents; Deuterium; Electrophoresis; gamma-Globulins; Humans; Hydrogen-Ion Concentration; Immunoglobulins; Infrared Rays; Iodoacetates; Macroglobulins; Spectrophotometry; Sulfuric Acids; Waldenstrom Macroglobulinemia

1971
Comparative studies on adrenal iron-sulfur protein and its selenium derivatives by electron nuclear double resonance.
    Biochimica et biophysica acta, 1973, Dec-06, Volume: 328, Issue:2

    Topics: Adrenal Glands; Animals; Apoproteins; Binding Sites; Cattle; Cysteine; Deuterium; Electron Spin Resonance Spectroscopy; Ferredoxins; Iron; Iron Isotopes; Isotopes; Protein Binding; Selenium; Sulfur

1973
The mode of action of N-methyl-N'-nitro-N-nitrosoguanidine in mutagenesis. VII. The transfer of the methyl group of N-methyl-N'-nitro-N-nitrosoguanidine.
    Biochimica et biophysica acta, 1972, May-10, Volume: 269, Issue:2

    Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; Deuterium; DNA; DNA, Bacterial; Escherichia coli; Guanidines; Guanine; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Mutagens; Nitro Compounds; Nitroso Compounds; Nitrosoguanidines; Quaternary Ammonium Compounds; Thymus Gland

1972
Cysteine-catalyzed hydrogen isotope exchange at the 5 position of uridylic acid.
    Journal of the American Chemical Society, 1972, Dec-13, Volume: 94, Issue:25

    Topics: Catalysis; Cysteine; Deuterium; Hydrogen; Isotope Labeling; Uracil Nucleotides

1972
On the mode of activation of the catalytically essential sulfhydryl group of papain.
    European journal of biochemistry, 1973, Feb-15, Volume: 33, Issue:1

    Topics: Acetamides; Acylation; Alkylation; Amides; Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Deuterium; Histidine; Hydrogen-Ion Concentration; Imidazoles; Iodoacetates; Kinetics; Papain; Sulfhydryl Compounds; X-Ray Diffraction

1973
Cysteine-catalyzed hydrogen isotope exchange at position 5 of uridylic acid.
    Journal of biochemistry, 1973, Volume: 73, Issue:4

    Topics: Amines; Catalysis; Cysteine; Deuterium; Isotope Labeling; Temperature; Uracil Nucleotides; Uridine

1973
Synthesis of S-alkyl-L-cysteine from pyruvate, ammonia and alkyl-mercaptan by cysteine desulfhydrase of Aerobacter aerogenes.
    Biochemical and biophysical research communications, 1974, Jul-24, Volume: 59, Issue:2

    Topics: Alkylation; Ammonia; Autoanalysis; Chromatography, Gel; Chromatography, Ion Exchange; Cystathionine; Cysteine; Deuterium; Electrophoresis, Polyacrylamide Gel; Enterobacter; Ethanol; Hydrogen-Ion Concentration; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Methanol; Molecular Weight; Pyruvates; Sulfhydryl Compounds; Time Factors

1974
[Synthesis of 3,4-dihydro-3-amino-7-hydroxycoumarin from S-methyl-l-cysteine and resorcinol by crystalline-beta-tyrosinase].
    Biochimica et biophysica acta, 1970, Jun-10, Volume: 206, Issue:3

    Topics: Catechol Oxidase; Coumarins; Cysteine; Deuterium; Escherichia; Kinetics; Magnetic Resonance Spectroscopy; Resorcinols

1970
Contact-shifted NMR of spinach ferredoxin: additional resonances and partial assignments.
    Archives of biochemistry and biophysics, 1972, Volume: 150, Issue:2

    Topics: Amino Acids; Cysteine; Deuterium; Ferredoxins; Iron; Magnetic Resonance Spectroscopy; Mathematics; Oxidation-Reduction; Plants

1972
Cystathionine -synthase. Studies of hydrogen exchange reactions.
    The Journal of biological chemistry, 1972, Oct-25, Volume: 247, Issue:20

    Topics: Alanine; Aminobutyrates; Catalysis; Chemical Phenomena; Chemistry; Cystathionine; Cysteine; Deuterium; Homoserine; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Salmonella; Serine; Succinates; Tritium

1972
Dissociation constants of lanthionine and its structure in aqueous solution.
    International journal of protein research, 1971, Volume: 3, Issue:5

    Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Chlorine; Computers; Cysteine; Deuterium; Dicarboxylic Acids; Hydrogen-Ion Concentration; Infrared Rays; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Nitrates; Optical Rotatory Dispersion; Potentiometry; Sodium; Spectrophotometry; Stereoisomerism; Sulfides; Temperature; Thermodynamics; Tosyl Compounds

1971
The nature of general base-general acid catalysis in serine proteases.
    Proceedings of the National Academy of Sciences of the United States of America, 1969, Volume: 64, Issue:4

    Topics: Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Deuterium; Endopeptidases; Histidine; Kinetics; Models, Chemical; Models, Structural; Serine

1969
Luminescence of the tryptophan and tyrosine residues of papain in solution.
    Biochemistry, 1970, Jan-06, Volume: 9, Issue:1

    Topics: Cold Temperature; Cysteine; Deuterium; Fluorescence; Glucose; Glycols; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Papain; Tryptophan; Tyrosine

1970
Lysine 2,3-aminomutase. Purification and properties of a pyridoxal phosphate and S-adenosylmethionine-activated enzyme.
    The Journal of biological chemistry, 1970, Apr-10, Volume: 245, Issue:7

    Topics: Acetone; Amino Acids; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Clostridium; Cysteine; Deuterium; Dialysis; Drug Stability; Electrophoresis; Electrophoresis, Disc; Enzyme Activation; Hydrogen-Ion Concentration; Hydroxylamines; Intramolecular Transferases; Iron; Isomerases; Isoniazid; Kinetics; Lysine; Methionine; Methods; Molecular Weight; Nucleosides; Pyridoxal Phosphate; Pyridoxine; Streptomycin; Sulfhydryl Compounds; Temperature; Tritium

1970
Kinetic and structural studies of hydroxyproline 2-epimerase.
    The Journal of biological chemistry, 1970, Oct-25, Volume: 245, Issue:20

    Topics: Amino Acids; Benzoates; Binding Sites; Chromatography, Gel; Cysteine; Deuterium; Electrophoresis, Disc; Enzyme Induction; Hydroxyproline; Isomerases; Kinetics; Magnetic Resonance Spectroscopy; Molecular Weight; Peptides; Pseudomonas; Sulfides; Trypsin; Ultracentrifugation

1970
Biosynthesis of deuterated benzylpenicillins. I. Solvent deuterium oxide participation.
    Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:10

    Topics: Cysteine; Deuterium; Infrared Rays; Magnetic Resonance Spectroscopy; Oxides; Penicillin G; Spectrophotometry; Valine

1970
S methylation of thiols by O-methylisourea.
    Biochemistry, 1970, Aug-18, Volume: 9, Issue:17

    Topics: Acetates; Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Deuterium; Dipeptides; Ethanol; Glycine; Guanidines; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Mercaptoethanol; Methylation; Models, Biological; Sulfhydryl Compounds; Sulfhydryl Reagents; Time Factors; Urea

1970
Essential histidyl residues of octopine dehydrogenase.
    European journal of biochemistry, 1971, Jul-29, Volume: 21, Issue:2

    Topics: Animals; Carbonates; Cysteine; Deuterium; Dicarboxylic Acids; Guanidines; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; L-Lactate Dehydrogenase; Mollusca; Muscles; Oxidoreductases; Spectrophotometry; Tyrosine

1971
Repair and damage by mercaptans in 60Co gamma-ray irradiation of organic compounds in aqueous solution.
    Radiation research, 1971, Volume: 45, Issue:3

    Topics: 1-Propanol; Acetone; Catalysis; Chromatography, Gas; Cobalt Isotopes; Cysteine; Deuterium; Free Radicals; Hydrogen-Ion Concentration; Mercaptoethanol; Radiation Effects; Radiochemistry; Solutions; Spectrophotometry; Sulfhydryl Compounds; Water

1971
Proton retention in the gamma-elimination reaction catalysed by cystathionine gamma-synthase.
    Biochimica et biophysica acta, 1968, Mar-25, Volume: 151, Issue:3

    Topics: Cysteine; Deuterium; Dinitrophenols; Hydrazines; Hydro-Lyases; Hydrogen; Keto Acids; Magnetic Resonance Spectroscopy; Protons; Pyridoxal Phosphate; Serine; Succinates; Tritium; Water

1968
Metabolism of L-[sulfane-34S]thiocystine by Escherichia coli.
    Biochemistry, 1982, Aug-31, Volume: 21, Issue:18

    Topics: Cysteine; Cystine; Deuterium; Escherichia coli; Hydrogen Sulfide; Serine; Sulfur Isotopes

1982
Metabolism of haloforms to carbon monoxide. IV. studies on the reaction mechanism in vivo.
    Chemico-biological interactions, 1981, Volume: 37, Issue:3

    Topics: Animals; Carbon Monoxide; Carcinogens; Chloroform; Cysteine; Deuterium; Hydrocarbons, Brominated; Male; Maleates; Phenobarbital; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Trihalomethanes

1981
Solvent isotope effects on the rates of alkylation of thiolamine models of papain.
    FEBS letters, 1980, Jul-11, Volume: 116, Issue:1

    Topics: Alkylation; Binding Sites; Catalysis; Cysteine; Deuterium; Kinetics; Mercaptoethylamines; Models, Chemical; Papain; Solvents

1980
Observation of a second substrate radical intermediate in the reaction of lysine 2,3-aminomutase: a radical centered on the beta-carbon of the alternative substrate, 4-thia-L-lysine.
    Biochemistry, 1995, Aug-22, Volume: 34, Issue:33

    Topics: Amino Acid Isomerases; Clostridium; Cysteine; Deuterium; Electrochemistry; Electron Spin Resonance Spectroscopy; Intramolecular Transferases; Kinetics; S-Adenosylmethionine; Substrate Specificity

1995
Decreasing the basicity of the active site base, Lys-258, of Escherichia coli aspartate aminotransferase by replacement with gamma-thialysine.
    Biochemistry, 1995, Mar-28, Volume: 34, Issue:12

    Topics: Amino Acid Sequence; Aspartate Aminotransferases; Binding Sites; Cysteine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lysine; Mathematics; Mutagenesis, Site-Directed; Recombinant Proteins; Spectrophotometry; Structure-Activity Relationship; Thermodynamics

1995
Electron paramagnetic resonance evidence for a cysteine-based radical in pyruvate formate-lyase inactivated with mercaptopyruvate.
    Biochemistry, 1995, May-02, Volume: 34, Issue:17

    Topics: Acetyltransferases; Binding Sites; Cysteine; Deuterium; Disulfides; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Kinetics; Recombinant Proteins; Sulfhydryl Compounds

1995
Protein expression, selective isotopic labeling, and analysis of hyperfine-shifted NMR signals of Anabaena 7120 vegetative [2Fe-2S]ferredoxin.
    Archives of biochemistry and biophysics, 1995, Jan-10, Volume: 316, Issue:1

    Topics: Anabaena; Arginine; Bacterial Proteins; Base Sequence; Carbon Isotopes; Carrier Proteins; Cysteine; Deuterium; Ferredoxins; Isotope Labeling; Ligands; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nitrogen Isotopes; Recombinant Proteins

1995
Hydrogen exchange of the glycyl radical of pyruvate formate-lyase is catalyzed by cysteine 419.
    Biochemistry, 1995, Feb-28, Volume: 34, Issue:8

    Topics: Acetyltransferases; Binding Sites; Cysteine; Deuterium; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Glycine; Hydrogen; Ion Exchange; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction

1995
Measurement of excitatory sulfur amino acids, cysteine sulfinic acid, cysteic acid, homocysteine sulfinic acid, and homocysteic acid in serum by stable isotope dilution gas chromatography-mass spectrometry and selected ion monitoring.
    Analytical biochemistry, 1994, Aug-01, Volume: 220, Issue:2

    Topics: Aspartic Acid; Cysteic Acid; Cysteine; Deuterium; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Isotope Labeling; Neurotransmitter Agents; Reference Values

1994
Human placental aldose reductase: role of Cys-298 in substrate and inhibitor binding.
    Biochimica et biophysica acta, 1994, Apr-13, Volume: 1205, Issue:2

    Topics: Aldehyde Reductase; Aldehydes; Circular Dichroism; Cysteine; Deuterium; Female; Humans; Imidazoles; Imidazolidines; Iodoacetates; Iodoacetic Acid; Kinetics; NADP; Naphthalenes; Placenta; Pregnancy; Quercetin; Spectrophotometry, Ultraviolet

1994
Alternative model for mechanism-based inhibition of Escherichia coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine 5'-diphosphate.
    Biochemistry, 1993, Nov-30, Volume: 32, Issue:47

    Topics: Azides; Cysteine; Deoxyuracil Nucleotides; Deuterium; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Models, Chemical; Mutation; Nitrogen; Ribonucleotide Reductases; Spin Labels; Tyrosine

1993
In Azotobacter vinelandii hydrogenase, substitution of serine for the cysteine residues at positions 62, 65, 294, and 297 in the small (HoxK) subunit affects H2 oxidation [corrected].
    Journal of bacteriology, 1993, Volume: 175, Issue:11

    Topics: Amino Acid Sequence; Azotobacter vinelandii; Benzyl Viologen; Cysteine; Deuterium; Electron Transport; Hydrogen; Hydrogenase; Methylene Blue; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Phenotype

1993
1H-NMR and 13C-NMR investigation of complexes of Mn2+ with ocytocin analogues in (2H6)dimethylsulfoxide.
    European journal of biochemistry, 1996, Aug-15, Volume: 240, Issue:1

    Topics: Alanine; Amino Acid Sequence; Binding Sites; Carbon Isotopes; Cysteine; Deuterium; Dimethyl Sulfoxide; Glutamine; Hydrogen; Magnetic Resonance Spectroscopy; Manganese; Models, Molecular; Molecular Sequence Data; Oxytocin; Proline; Protein Binding; Protein Conformation; Sarcosine; Sulfhydryl Compounds; Thermodynamics; Threonine

1996
Structural characterization of an analog of the major rate-determining disulfide folding intermediate of bovine pancreatic ribonuclease A.
    Biochemistry, 1997, Oct-21, Volume: 36, Issue:42

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cattle; Cloning, Molecular; Computer Simulation; Crystallography, X-Ray; Cysteine; Deuterium; Disulfides; Entropy; Escherichia coli; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Pancreas; Polymerase Chain Reaction; Protein Conformation; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Ribonuclease, Pancreatic; Software; Thermodynamics

1997
Solution structure of the antimicrobial peptide ranalexin and a study of its interaction with perdeuterated dodecylphosphocholine micelles.
    European journal of biochemistry, 1998, Apr-01, Volume: 253, Issue:1

    Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Circular Dichroism; Cysteine; Deuterium; Escherichia coli; Magnetic Resonance Spectroscopy; Micelles; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Peptides, Cyclic; Phosphorylcholine; Protein Conformation; Protein Structure, Secondary; Rana catesbeiana; Skin; Solutions; Staphylococcus epidermidis; Trifluoroethanol; Water

1998
Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate.
    Biochemistry, 1998, Jul-28, Volume: 37, Issue:30

    Topics: Alanine; Binding Sites; Circular Dichroism; Cysteine; Cysteine Synthase; Deuterium; Enzyme Activation; Enzyme Stability; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Insertional; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1998
Conformational and dynamic changes of Yersinia protein tyrosine phosphatase induced by ligand binding and active site mutation and revealed by H/D exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.
    Biochemistry, 1998, Nov-03, Volume: 37, Issue:44

    Topics: Amino Acid Sequence; Binding Sites; Cyclotrons; Cysteine; Deuterium; Endopeptidases; Hydrogen; Hydrolysis; Ligands; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; Protein Conformation; Protein Tyrosine Phosphatases; Serine; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Threonine; Yersinia

1998
Kinetic mechanism of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase.
    Biochemistry, 1999, Feb-23, Volume: 38, Issue:8

    Topics: Amino Acid Substitution; Animals; Binding Sites; Cysteine; Deuterium; Humans; IMP Dehydrogenase; Kinetics; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Mycophenolic Acid; NAD; Protein Binding; Serine; Spectrometry, Fluorescence; Thermodynamics; Tritrichomonas foetus

1999
Catalytic acid/base residues of glutamate racemase.
    Biochemistry, 1999, Mar-30, Volume: 38, Issue:13

    Topics: Amino Acid Isomerases; Amino Acids; Catalysis; Cysteine; Deuterium; Glutamates; Hydrogen-Ion Concentration; Kinetics; Lactobacillus; Mutagenesis, Site-Directed; Serine; Stereoisomerism

1999
Mechanism of 3-methylaspartase probed using deuterium and solvent isotope effects and active-site directed reagents: identification of an essential cysteine residue.
    Bioorganic & medicinal chemistry, 1999, Volume: 7, Issue:5

    Topics: Ammonia; Ammonia-Lyases; Binding Sites; Chromatography, High Pressure Liquid; Cysteine; Deuterium; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Kinetics; Magnesium; Models, Chemical; Models, Molecular; Protein Conformation; Time Factors

1999
Electron-nuclear interactions in two prototypical [2Fe-2S] proteins: selective (chiral) deuteration and analysis of (1)H and (2)H NMR signals from the alpha and beta hydrogens of cysteinyl residues that ligate the iron in the active sites of human ferredo
    Archives of biochemistry and biophysics, 2000, Jan-15, Volume: 373, Issue:2

    Topics: Anabaena; Binding Sites; Carbon-Oxygen Lyases; Cysteine; Deuterium; Electrons; Escherichia coli; Ferredoxins; Humans; Hydrogen; Iron-Sulfur Proteins; Magnetic Resonance Spectroscopy; Models, Molecular; Plant Proteins; Protein Conformation; Recombinant Proteins

2000
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
    Biochemistry, 2000, Aug-08, Volume: 39, Issue:31

    Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan

2000
Mutational analysis of metallo-beta-lactamase CcrA from Bacteroides fragilis.
    Biochemistry, 2000, Sep-19, Volume: 39, Issue:37

    Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Bacterial Proteins; Bacteroides fragilis; beta-Lactamases; Cysteine; Deuterium; DNA Mutational Analysis; DNA, Bacterial; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Kinetics; Metalloproteins; Mutagenesis, Site-Directed; Protons; Recombinant Proteins; Serine; Solvents; Zinc

2000
The asparagine-stabilized beta-turn of apamin: contribution to structural stability from dynamics simulation and amide hydrogen exchange analysis.
    Biochemistry, 2000, Dec-26, Volume: 39, Issue:51

    Topics: Amides; Amino Acid Sequence; Amino Acid Substitution; Animals; Apamin; Asparagine; Cysteine; Deuterium; Disulfides; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peptides; Protein Conformation; Protein Structure, Secondary; Thermodynamics

2000
Identification of active site residues in E. coli ketopantoate reductase by mutagenesis and chemical rescue.
    Biochemistry, 2000, Dec-26, Volume: 39, Issue:51

    Topics: Acetic Acid; Alanine; Alcohol Oxidoreductases; Alkylation; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Cysteine; Deuterium; Escherichia coli; Formates; Gene Expression Regulation, Bacterial; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Pantothenic Acid; Recombinant Proteins; Sequence Alignment; Substrate Specificity

2000
ESEEM and mims ENDOR spectroscopies of cis,trans-(L-N2S2)MoVO(SCH2Ph): detection of the two benzylthiolate alpha protons.
    Inorganic chemistry, 2000, Oct-16, Volume: 39, Issue:21

    Topics: Animals; Binding Sites; Chickens; Cysteine; Desulfovibrio; Deuterium; Electron Spin Resonance Spectroscopy; Eukaryota; Liver; Molybdenum; Nitrate Reductase; Nitrate Reductases; Oxidoreductases Acting on Sulfur Group Donors; Paracoccus; Plants

2000
Requirement of glutathione and cysteine in guanine-specific oxidation of DNA by carcinogenic potassium bromate.
    Chemical research in toxicology, 2001, Volume: 14, Issue:6

    Topics: Animals; Antineoplastic Agents; Bromates; Carcinogens; Cell Transformation, Neoplastic; Cysteine; Deuterium; DNA Damage; Food Additives; Free Radicals; Genes, p53; Genes, ras; Glutathione; Guanine; HL-60 Cells; Humans; Kidney Neoplasms; Rats; Spin Trapping

2001
Intramolecular interactions in chemically modified Escherichia coli thioredoxin monitored by hydrogen/deuterium exchange and electrospray ionization mass spectrometry.
    Biochemistry, 2001, Dec-04, Volume: 40, Issue:48

    Topics: Alkylation; Chromatography, High Pressure Liquid; Cysteine; Deuterium; Escherichia coli; Glutathione; Hydrogen; Kinetics; Oxidation-Reduction; Peptide Fragments; Protein Conformation; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Thioredoxins

2001
Hydrogenases in the "active" state: determination of g-matrix axes and electron spin distribution at the active site by 1H ENDOR spectroscopy.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2002, Volume: 7, Issue:1-2

    Topics: Binding Sites; Computer Simulation; Cysteine; Deuterium; Electron Spin Resonance Spectroscopy; Electrons; Hydrogenase; Iron; Models, Molecular; Nickel; Proteobacteria; Protons; Selenium; Spectrum Analysis; Sulfur

2002
Hydrogen/deuterium exchange and mass spectrometric analysis of a protein containing multiple disulfide bonds: Solution structure of recombinant macrophage colony stimulating factor-beta (rhM-CSFbeta).
    Protein science : a publication of the Protein Society, 2002, Volume: 11, Issue:9

    Topics: Amino Acid Sequence; Cysteine; Deuterium; Disulfides; Humans; Hydrogen; Macrophage Colony-Stimulating Factor; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Peptides; Protein Conformation; Protein Subunits; Recombinant Proteins; Solvents; Time Factors

2002
Conformational analysis of intermediates involved in the in vitro folding pathways of recombinant human macrophage colony stimulating factor beta by sulfhydryl group trapping and hydrogen/deuterium pulsed labeling.
    Biochemistry, 2002, Dec-31, Volume: 41, Issue:52

    Topics: Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine; Deuterium; Dimerization; Disulfides; Humans; Kinetics; Macrophage Colony-Stimulating Factor; Oxidation-Reduction; Peptide Mapping; Protein Conformation; Protein Denaturation; Protein Folding; Protons; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds

2002
The unusual catalytic triad of poliovirus protease 3C.
    Biochemistry, 2003, Jan-21, Volume: 42, Issue:2

    Topics: 3C Viral Proteases; Catalysis; Catalytic Domain; Cysteine; Cysteine Endopeptidases; Deuterium; Glutamic Acid; Glutamine; Glycine; Hydrogen-Ion Concentration; Kinetics; Methionine; Models, Chemical; Mutagenesis, Site-Directed; Poliovirus; Serine; Solvents; Substrate Specificity; Temperature; Thermodynamics; Viral Proteins

2003
Analysis of the effect of potato carboxypeptidase inhibitor pro-sequence on the folding of the mature protein.
    European journal of biochemistry, 2003, Volume: 270, Issue:17

    Topics: Amino Acid Sequence; Carboxypeptidases; Circular Dichroism; Cysteine; Deuterium; Enzyme Precursors; Escherichia coli; Kinetics; Leucyl Aminopeptidase; Molecular Sequence Data; Mutagenesis; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peptide Fragments; Plant Proteins; Protease Inhibitors; Protein Denaturation; Protein Folding; Protein Renaturation; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2003
IRON REQUIREMENT FOR THE HYDROGENASE OF DESULFOVIBRIO DESULFURICANS.
    Archives of biochemistry and biophysics, 1964, Volume: 108

    Topics: Coumarins; Cysteine; Desulfovibrio; Desulfovibrio desulfuricans; Deuterium; Hydrogenase; Iron; Metabolism; Oxidoreductases

1964
Direct determination of the interleukin-6 binding epitope of the interleukin-6 receptor by NMR spectroscopy.
    The Journal of biological chemistry, 2004, Jan-02, Volume: 279, Issue:1

    Topics: Binding Sites; Cloning, Molecular; Conserved Sequence; Cysteine; Deuterium; Escherichia coli; Interleukin-6; Magnetic Resonance Spectroscopy; Models, Molecular; Nitrogen Isotopes; Protein Conformation; Receptors, Interleukin-6; Recombinant Proteins

2004
A new deuterated alkylating agent for quantitative proteomics.
    Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:21

    Topics: Alkylating Agents; Alkylation; Amino Acid Sequence; Animals; Cattle; Cysteine; Deuterium; Humans; Hydrogen-Ion Concentration; Isotope Labeling; Molecular Sequence Data; Molecular Weight; Muramidase; Proteins; Proteomics; Surface-Active Agents

2003
Probing the mechanism of hamster arylamine N-acetyltransferase 2 acetylation by active site modification, site-directed mutagenesis, and pre-steady state and steady state kinetic studies.
    Biochemistry, 2004, Jun-29, Volume: 43, Issue:25

    Topics: Acetamides; Acetyl Coenzyme A; Acetylation; Alkylating Agents; Amino Acid Sequence; Amino Acid Substitution; Animals; Arylamine N-Acetyltransferase; Binding Sites; Cricetinae; Cysteine; Deuterium; Enzyme Inhibitors; Hydrogen-Ion Concentration; Iodoacetamide; Isoenzymes; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrophenols; Papain; Protein Conformation; Recombinant Proteins

2004
Evidence for accelerated rates of glutathione utilization and glutathione depletion in adolescents with poorly controlled type 1 diabetes.
    Diabetes, 2005, Volume: 54, Issue:1

    Topics: Adolescent; Blood Glucose; Body Size; Cysteine; Deuterium; Diabetes Mellitus, Type 1; Erythrocytes; Female; Glutathione; Humans; Infusions, Intravenous; Male; Radioisotope Dilution Technique; Reference Values

2005
Resonance assignments and secondary structureof hPrxVI, a 25 kDa 1-cys human peroxiredoxin enzyme.
    Journal of biomolecular NMR, 2005, Volume: 31, Issue:3

    Topics: Amino Acid Sequence; Asparagine; Carbon Isotopes; Cysteine; Deuterium; Escherichia coli; Glycine; Humans; Molecular Sequence Data; Molecular Weight; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peroxidases; Peroxiredoxins; Protein Structure, Secondary; Protons

2005
Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes.
    Biophysical journal, 2006, Jan-15, Volume: 90, Issue:2

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides; Biophysics; Cysteine; Deuterium; Deuterium Oxide; Electron Spin Resonance Spectroscopy; Lipids; Magnetics; Models, Chemical; Models, Statistical; Molecular Sequence Data; Nitric Oxide; Ovum; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Structure, Tertiary; Spin Labels; Temperature; Time Factors

2006
Accelerated on-column lysine derivatization and cysteine methylation by imidazole reaction in a deuterated environment for enhanced product ion analysis.
    Rapid communications in mass spectrometry : RCM, 2006, Volume: 20, Issue:4

    Topics: Amino Acid Sequence; Cysteine; Deuterium; Erythropoietin; Humans; Imidazoles; Interferon alpha-2; Interferon-alpha; Lysine; Metalloendopeptidases; Methylation; Molecular Sequence Data; Molecular Structure; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Trypsin

2006
Methionine kinetics are altered in the elderly both in the basal state and after vaccination.
    The American journal of clinical nutrition, 2006, Volume: 83, Issue:2

    Topics: Adult; Aged; Aging; Carbon Isotopes; Cysteine; Deuterium; Female; Homocysteine; Humans; Inflammation; Isotope Labeling; Male; Mathematics; Methionine; Methylation; Nutritional Requirements; Postprandial Period; Vaccination

2006
Knots in rings. The circular knotted protein Momordica cochinchinensis trypsin inhibitor-II folds via a stable two-disulfide intermediate.
    The Journal of biological chemistry, 2006, Mar-24, Volume: 281, Issue:12

    Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cattle; Chromatography, High Pressure Liquid; Cyclotides; Cysteine; Deuterium; Disulfides; Hydrogen; In Vitro Techniques; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Chaperones; Molecular Conformation; Molecular Sequence Data; Oxygen; Plant Proteins; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Spectrometry, Mass, Electrospray Ionization; Trypsin; Trypsin Inhibitors

2006
Quantitative analysis of acrylamide labeled serum proteins by LC-MS/MS.
    Journal of proteome research, 2006, Volume: 5, Issue:8

    Topics: Acrylamides; Algorithms; Alkylation; Amino Acid Sequence; Blood Proteins; Carbon Radioisotopes; Chromatography, Liquid; Cysteine; Deuterium; Humans; Mass Spectrometry; Molecular Sequence Data

2006
Mass spectrometry-based glycoproteomic approach involving lysine derivatization for structural characterization of recombinant human erythropoietin.
    Journal of proteome research, 2006, Volume: 5, Issue:11

    Topics: Amino Acid Sequence; Cysteine; Deuterium; Erythropoietin; Glycoproteins; Glycosylation; Humans; Lysine; Molecular Sequence Data; Peptide Fragments; Polysaccharides; Proteomics; Recombinant Proteins; Trypsin

2006
Catalytic mechanism of Zn2+-dependent polyol dehydrogenases: kinetic comparison of sheep liver sorbitol dehydrogenase with wild-type and Glu154-->Cys forms of yeast xylitol dehydrogenase.
    The Biochemical journal, 2007, Jun-15, Volume: 404, Issue:3

    Topics: Animals; Cysteine; D-Xylulose Reductase; Deuterium; Enzyme Inhibitors; Fungal Proteins; Glutamic Acid; Humans; Hydrogen-Ion Concentration; L-Iditol 2-Dehydrogenase; Liver; Molecular Structure; NAD; Oxidation-Reduction; Point Mutation; Sheep; Solvents; Sorbitol; Zinc

2007
Are carboxyl groups the most acidic sites in amino acids? Gas-phase acidity, H/D exchange experiments, and computations on cysteine and its conjugate base.
    Journal of the American Chemical Society, 2007, May-02, Volume: 129, Issue:17

    Topics: Acids; Amino Acids; Benzyl Alcohol; Cysteine; Deuterium; Fourier Analysis; Gases; Hydrogen; Hydrogen Bonding; Mass Spectrometry; Molecular Conformation; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds

2007
Toward a property/function relationship for metallothioneins: histidine coordination and unusual cluster composition in a zinc-metallothionein from plants.
    Proteins, 2007, Sep-01, Volume: 68, Issue:4

    Topics: Amino Acid Sequence; Cysteine; Databases, Protein; Deuterium; Histidine; Metallothionein; Plant Proteins; Sequence Alignment; Sequence Homology, Amino Acid

2007
A novel pyrimidine-based stable-isotope labeling reagent and its application to quantitative analysis using matrix-assisted laser desorption/ionization mass spectrometry.
    Journal of mass spectrometry : JMS, 2007, Volume: 42, Issue:11

    Topics: Animals; Chickens; Cysteine; Deuterium; Hydrogen-Ion Concentration; Isotope Labeling; Muramidase; Peptides; Proteins; Pyrimidines; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin

2007
Isotope-coded, iodoacetamide-based reagent to determine individual cysteine pK(a) values by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
    Analytical biochemistry, 2008, Apr-15, Volume: 375, Issue:2

    Topics: Acetanilides; Cysteine; Deuterium; Hydrogen-Ion Concentration; Indicators and Reagents; Iodoacetamide; Isotopes; Kinetics; Oxidation-Reduction; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Thioredoxins; Titrimetry

2008
Quantification of cysteine S-conjugate of 3-sulfanylhexan-1-ol in must and wine of petite arvine vine by stable isotope dilution analysis.
    Journal of agricultural and food chemistry, 2008, May-14, Volume: 56, Issue:9

    Topics: Cysteine; Deuterium; Fermentation; Fruit; Hexanols; Indicator Dilution Techniques; Sulfhydryl Compounds; Vitis; Wine

2008
Gas-phase fragmentation of long-lived cysteine radical cations formed via NO loss from protonated S-nitrosocysteine.
    Journal of the American Society for Mass Spectrometry, 2009, Volume: 20, Issue:6

    Topics: Cations; Cysteine; Deuterium; Gases; Isomerism; Models, Chemical; Nitrites; Protons; S-Nitrosoglutathione; S-Nitrosothiols; Spectrometry, Mass, Electrospray Ionization; Thermodynamics

2009
Detection of the sulfhydryl groups in proteins with slow hydrogen exchange rates and determination of their proton/deuteron fractionation factors using the deuterium-induced effects on the 13C(beta) NMR signals.
    Journal of the American Chemical Society, 2010, May-05, Volume: 132, Issue:17

    Topics: Carbon Isotopes; Cysteine; Deuterium; Hydrogen; Nuclear Magnetic Resonance, Biomolecular; Proteins; Protons

2010
Excretion of 2,3-dihydroxy-propionamide (OH-PA), the hydrolysis product of glycidamide, in human urine after single oral dose of deuterium-labeled acrylamide.
    Archives of toxicology, 2011, Volume: 85, Issue:6

    Topics: Acetamides; Acetylcysteine; Acrylamide; Adult; Amides; Analytic Sample Preparation Methods; Carcinogens; Cysteine; Deuterium; Epoxy Compounds; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Indicators and Reagents; Male; Organosilicon Compounds; Oxidation-Reduction; Silanes; Sulfoxides; Trifluoroacetic Acid

2011
Unique cyanide adduct in human serum albumin: potential as a surrogate exposure marker.
    Chemical research in toxicology, 2011, Apr-18, Volume: 24, Issue:4

    Topics: Biomarkers; Chromatography, High Pressure Liquid; Cyanides; Cysteine; Deuterium; Disulfides; Humans; Peptides; Serum Albumin; Tandem Mass Spectrometry

2011
Specific racemization of heavy-chain cysteine-220 in the hinge region of immunoglobulin gamma 1 as a possible cause of degradation during storage.
    Analytical chemistry, 2011, May-15, Volume: 83, Issue:10

    Topics: Amino Acid Sequence; Cysteine; Deuterium; Humans; Hydrogen-Ion Concentration; Hydrolysis; Immunoglobulin G; Peptide Mapping; Tandem Mass Spectrometry; Temperature; Time Factors

2011
Conformational analysis by quantitative NOE measurements of the β-proton pairs across individual disulfide bonds in proteins.
    Journal of biomolecular NMR, 2012, Volume: 52, Issue:2

    Topics: Animals; Cattle; Cysteine; Deuterium; Disulfides; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Protons; Trypsin Inhibitors

2012
Isotope-coded protein label.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 893

    Topics: Animals; Carbon Isotopes; Chemical Precipitation; Cysteine; Data Interpretation, Statistical; Deuterium; Electrophoresis, Gel, Two-Dimensional; Humans; Isotope Labeling; Mass Spectrometry; Methylation; Peptide Fragments; Proteolysis; Proteome; Reference Standards; Serine Endopeptidases; Software; Succinimides

2012
An approach for triplex-isobaric peptide termini labeling (triplex-IPTL).
    Analytical chemistry, 2013, Feb-19, Volume: 85, Issue:4

    Topics: Apoptosis; Carbon Isotopes; Cell Cycle Checkpoints; Cysteine; Deuterium; HeLa Cells; Humans; Isotope Labeling; Peptides; Tandem Mass Spectrometry

2013
Syntheses of deuterium labeled prenyldiphosphate and prenylcysteine analogues for in vivo mass spectrometric quantification.
    Journal of labelled compounds & radiopharmaceuticals, 2013, Jun-30, Volume: 56, Issue:8

    Topics: Cysteine; Deuterium; Isotope Labeling; Mass Spectrometry; Polyisoprenyl Phosphates

2013
Sequence-specific formation of d-amino acids in a monoclonal antibody during light exposure.
    Molecular pharmaceutics, 2014, Nov-03, Volume: 11, Issue:11

    Topics: Amino Acids; Antibodies, Monoclonal; Chromatography, High Pressure Liquid; Cysteine; Deuterium; Deuterium Exchange Measurement; Disulfides; Humans; Hydrogen; Hydrogen Bonding; Light; Peptide Fragments; Photolysis; Tandem Mass Spectrometry

2014
Human DNMT1 transition state structure.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, Mar-15, Volume: 113, Issue:11

    Topics: Binding, Competitive; Carbon Isotopes; Carbon Radioisotopes; Catalysis; Cysteine; Cytosine; Deuterium; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Humans; Kinetics; Models, Molecular; Protein Structure, Tertiary; Recombinant Fusion Proteins; S-Adenosylhomocysteine; Tritium

2016