deuterium has been researched along with cysteine in 97 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 32 (32.99) | 18.7374 |
1990's | 23 (23.71) | 18.2507 |
2000's | 32 (32.99) | 29.6817 |
2010's | 10 (10.31) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Anderson, BM; Chan, JK | 1 |
Finley, JW; Friedman, M; Snow, JT | 1 |
Krishna, G; Pohl, LR | 1 |
Hruby, VJ; Upson, DA | 1 |
Choi, SY; Esaki, N; Soda, K; Yoshimura, T | 1 |
Anders, MW; Fitzsimmons, ME; Harris, JW | 1 |
Arakawa, T; Prestrelski, SJ | 1 |
Commandeur, JN; Stijntjes, GJ; Vermeulen, NP; Wijngaard, J | 1 |
Gaskell, SJ; Orkiszewski, RS; Raftery, MJ; Thorne, GC | 1 |
Davidson, VL; Husain, M; Loehr, TM; Sanders-Loehr, J; Sharma, KD | 1 |
Kiick, DM; Phillips, RS | 2 |
Miller, JN | 1 |
Bowman, M; Kevan, L; Kimura, T; Mukai, K | 1 |
Haerlin, R; Lingens, F; Süssmuth, R | 1 |
Hayatsu, H; Kawazoe, Y; Wataya, Y | 2 |
Polgár, L | 1 |
Choi, Y; Kumagai, H; Sejima, S; Yamada, H | 1 |
Fukami, H; Kumagai, H; Ohkishi, H; Ueno, T; Yamada, H | 1 |
Palmer, G; Salmeen, I | 1 |
Flavin, M; Posner, BI | 1 |
Stapleton, IW; Weber, OA | 1 |
Bender, ML; Polgár, L | 1 |
Steiner, RF; Weinryb, I | 1 |
Barker, HA; Chirpich, TP; Costilow, RN; Zappia, V | 1 |
Adams, E; Finlay, TH | 1 |
Blake, MI; Carlstedt, BC; Crespi, HL; Katz, JJ | 1 |
Banks, TE; Shafer, JA | 1 |
Huc, C; Olomucki, A | 1 |
Cohen, SG; Lam, FL | 1 |
Flavin, M; Guggenheim, S | 1 |
White, RH | 1 |
Anders, MW; Stevens, JL | 1 |
Creighton, DJ; Wandinger, A | 1 |
Frey, PA; Lieder, KW; Reed, GH; Wu, W | 1 |
Gloss, LM; Kirsch, JF | 1 |
Kozarich, JW; Magliozzo, RS; Parast, CV; Peisach, J; Wong, KK | 1 |
Cheng, H; Markley, JL; Oh, BH; Westler, WM; Xia, B | 1 |
Kozarich, JW; Lewisch, SA; Magliozzo, RS; Parast, CV; Peisach, J; Wong, KK | 1 |
Deutsch, JC; Hassell, KL; Kolhouse, JC; Kolhouse, JF; Santhosh-Kumar, CR | 1 |
Chapman, TE; Cortiella, J; Fukagawa, NK; Hiramatsu, T; Marchini, JS; Young, VR; Yu, YM | 1 |
Bhatnagar, A; Chakrabarti, B; Liu, SQ; Srivastava, SK; Ueno, N | 1 |
Ator, M; Bollinger, JM; McCraken, J; Peisach, J; Robins, MJ; Salowe, S; Samano, MC; Stubbe, J | 1 |
Arp, DJ; Sayavedra-Soto, LA | 1 |
Gaggelli, E; Grzonka, Z; Kasprzykowski, F; Kozlowski, H; Maccotta, A; Valensin, G | 1 |
Laity, JH; Lester, CC; Montelione, GT; Scheraga, HA; Shimotakahara, S; Zimmerman, DE | 1 |
Aumelas, A; Calas, B; Chavanieu, A; Chiche, L; Grassy, G; Roch, P; Vignal, E | 1 |
Cook, PF; Kim, SK; Kredich, NM; Nalabolu, SR; Rege, VD; Schnackerz, KD; Tai, CH; Yoon, MY | 1 |
Emmett, MR; Hendrickson, CL; Li, W; Marshall, AG; Wang, F; Wu, L; Zhang, YL; Zhang, ZY | 1 |
Digits, JA; Hedstrom, L | 1 |
Glavas, S; Tanner, ME | 1 |
Akhtar, M; Botting, NP; Gani, D; Lasry, P; Neal, T; Pollard, JR; Richardson, S | 1 |
Jenk, D; LeMaster, DM; Markley, JL; Westler, WM; Xia, B | 1 |
Ferry, JG; Tripp, BC | 1 |
Crowder, MW; Taylor, RA; Yanchak, MP | 1 |
Campbell, SJ; Dempsey, CE; Lamble, NV; Sessions, RB | 1 |
Blanchard, JS; Zheng, R | 1 |
Astashkin, AV; Cosper, MM; Enemark, JH; Raitsimring, AM | 1 |
Bansho, Y; Inoue, S; Ito, K; Kawanishi, S; Midorikawa, K; Murata, M; Ohnishi, S | 1 |
Deinzer, ML; Ho, PS; Kim, MY; Maier, CS; Reed, DJ | 1 |
Cammack, R; Hatchikian, C; Hüttermann, J; Kappl, R; Müller, A; Tscherny, I | 1 |
Deinzer, ML; Schimerlik, MI; Watson, J; Yan, X; Zhang, H | 1 |
Deinzer, ML; Maier, CS; Schimerlik, MI; Yan, X; Zhang, YH | 1 |
Polgár, L; Sárkány, Z | 1 |
Ball, RO; Cole, DE; Di Buono, M; Pencharz, PB; Wykes, LJ | 1 |
Aviles, FX; Bronsoms, S; Canals, F; Querol, E; Villanueva, J | 1 |
RITTENBERG, D; SADANA, JC | 1 |
Dingley, AJ; Grötzinger, J; Ozbek, S; Rose-John, S; Schwantner, A | 1 |
Citterio, A; Lapadula, M; Righetti, PG; Sebastiano, R | 1 |
Gleason, KJ; Hanna, PE; Vath, GM; Wagner, CR; Wang, H | 1 |
Darmaun, D; Mauras, N; Sager, BK; Smith, SD; Sweeten, S; Welch, S | 1 |
Hong, E; Kang, SW; Lee, W; Shin, J; Tanaka, T | 1 |
Carmieli, R; Goldfarb, D; Papo, N; Potapov, A; Shai, Y; Zimmermann, H | 1 |
Bindila, L; Cepo, T; Cindrić, M; Skrlin, A; Vuletić, M | 1 |
Breuillé, D; Buffière, C; Gimonet, J; Mercier, S; Mirand, PP; Obled, C; Papet, I | 1 |
Cemazar, M; Craik, DJ; Daly, NL; Häggblad, S; Lo, KP; Yulyaningsih, E | 1 |
Coram, M; Faca, V; Fitzgibbon, M; Glukhova, V; Hanash, S; McIntosh, M; Phanstiel, D; Zhang, Q | 1 |
Bindila, L; Cepo, T; Cindrić, M; Peter-Katalinić, J | 1 |
Hellmer, H; Klimacek, M; Nidetzky, B | 1 |
Kass, SR; Pawlow, A; Poutsma, JC; Tian, Z | 1 |
Blindauer, CA; Leszczyszyn, OI; Schmid, R | 1 |
Guo, YL; Zhang, J; Zhang, L; Zhou, Y | 1 |
Day, AE; King, SB; Nelson, KJ; Poole, LB; Zeng, BB | 1 |
Buettner, H; Frey, U; Luisier, JL; Rausis, T; Völker, S | 1 |
Lam, AK; O'Hair, RA; Ryzhov, V | 1 |
Jee, J; Kainosho, M; Takeda, M; Terauchi, T | 1 |
Angerer, J; Hartmann, EC; Koch, HM; Latzin, JM; Schindler, BK | 1 |
Aldous, KM; Dailey, M; Fasco, MJ; Hauer, CR; Lu, S; Schneider, E; Stack, RF | 1 |
Amano, M; Fukui, K; Hasegawa, J; Kishi, N; Kobayashi, N; Nakazawa, T; Uchiyama, S | 1 |
Kainosho, M; Takeda, M; Terauchi, T | 1 |
Kellermann, J; Lottspeich, F | 1 |
Arntzen, MØ; de Souza, GA; Koehler, CJ; Thiede, B | 1 |
Morris, AJ; Onono, FO; Spielmann, HP; Subramanian, KL; Subramanian, T; Sunkara, M | 1 |
Mozziconacci, O; Schöneich, C | 1 |
Du, Q; Schramm, VL; Wang, Z | 1 |
2 trial(s) available for deuterium and cysteine
Article | Year |
---|---|
Methionine and cysteine kinetics at different intakes of cystine in healthy adult men.
Topics: Adult; Carbon Isotopes; Cysteine; Cystine; Deuterium; Dietary Proteins; Humans; Infusions, Intravenous; Kinetics; Male; Methionine; Oxidation-Reduction | 1994 |
Regulation of sulfur amino acid metabolism in men in response to changes in sulfur amino acid intakes.
Topics: Adult; Amino Acids, Sulfur; Carbon Isotopes; Cross-Over Studies; Cysteine; Deuterium; Diet; Dietary Proteins; Homocysteine; Humans; Kinetics; Male; Methionine; Methylation; Nutritional Requirements | 2003 |
95 other study(ies) available for deuterium and cysteine
Article | Year |
---|---|
Conformation of Escherichia coli glutamic acid tRNA II as studied by hydrogen-tritium exchange catalyzed by cysteine methyl ester.
Topics: Base Sequence; Binding Sites; Cysteine; Deuterium; DNA; Escherichia coli; Glutamates; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Nucleic Acid Denaturation; RNA, Bacterial; RNA, Transfer; Tritium | 1976 |
A novel diazonium-sulfhydryl reaction in the inactivation of yeast alcohol dehydrogenase by diazotized 3-aminopyridine adenine dinucleotide.
Topics: Alcohol Oxidoreductases; Amino Acids; Azo Compounds; Benzoates; Binding Sites; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; Deuterium; Disulfides; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; NAD; Nitro Compounds; Protein Binding; Saccharomyces cerevisiae; Spectrophotometry; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Time Factors | 1975 |
Oxidation of sulfhydryl groups to disulfides by sulfoxides.
Topics: Chemical Phenomena; Chemistry; Cysteine; Deuterium; Disulfides; Glutathione; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Penicillamine; Sulfhydryl Compounds; Sulfoxides; Valine | 1975 |
Deuterium isotope effect in bioactivation and hepatotoxicity of chloroform.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Cysteine; Cytochrome P-450 Enzyme System; Deuterium; Male; Microsomes, Liver; Phenobarbital; Rats; Thiazoles | 1978 |
Synthesis of specifically deuterated S-benzylcysteines and of oxytocin and related diastereomers deuterated in the half-cystine positions.
Topics: Benzyl Compounds; Chemical Phenomena; Chemistry; Cysteine; Deuterium; Isotope Labeling; Methods; Oxytocin; Stereoisomerism | 1976 |
Reaction mechanism of glutamate racemase, a pyridoxal phosphate-independent amino acid racemase.
Topics: Amino Acid Isomerases; Bacterial Proteins; Cysteine; Deuterium; Enzyme Activation; Glutamates; Glutamic Acid; Kinetics; Magnetic Resonance Spectroscopy; Pediococcus; Pyridoxal Phosphate; Sulfhydryl Compounds; Tritium | 1992 |
Synthesis of [2-3H-ethyl]S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine and its use in covalent-binding studies.
Topics: Animals; Cysteine; Cytosol; Deuterium; Kidney; Liver; Lysine; Magnetic Resonance Spectroscopy; Microsomes; Mitochondria; Rats; Rats, Inbred F344; Tritium | 1992 |
The solution structure and conformational dynamics of tumor necrosis factor-alpha and a (Cys69----Asp; Cys101----Arg) analog as examined by IR spectroscopy and hydrogen exchange.
Topics: Animals; Arginine; Aspartic Acid; Cysteine; Deuterium; Hydrogen; Mutagenesis, Site-Directed; Protein Conformation; Spectrophotometry, Infrared; Tumor Necrosis Factor-alpha | 1991 |
Metabolism of L-cysteine S-conjugates and N-(trideuteroacetyl)-L-cysteine S-conjugates of four fluoroethylenes in the rat. Role of balance of deacetylation and acetylation in relation to the nephrotoxicity of mercapturic acids.
Topics: Acetylation; Acetylcysteine; Amidohydrolases; Animals; Arylamine N-Acetyltransferase; Bile; Chlorofluorocarbons; Cysteine; Deuterium; Ethylenes; Gas Chromatography-Mass Spectrometry; Hydrocarbons, Fluorinated; Hydrocarbons, Halogenated; Kidney; Kidney Diseases; Liver; Male; Rats; Rats, Inbred Strains; Subcellular Fractions | 1991 |
Preparation and tandem mass spectrometric analyses of deuterium-labeled cysteine-containing leukotrienes.
Topics: Cysteine; Deuterium; Indicators and Reagents; Isotope Labeling; Mass Spectrometry; SRS-A | 1990 |
Resonance Raman spectroscopy of amicyanin, a blue copper protein from Paracoccus denitrificans.
Topics: Azurin; Bacterial Proteins; Binding Sites; Copper; Cysteine; Deuterium; Electron Spin Resonance Spectroscopy; Metalloproteins; Paracoccus denitrificans; Plastocyanin; Spectrum Analysis, Raman | 1988 |
Mechanistic deductions from multiple kinetic and solvent deuterium isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Escherichia coli tryptophan indole-lyase.
Topics: Alanine; Binding, Competitive; Catalysis; Cysteine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lyases; Oxindoles; Pyridoxal Phosphate; Solvents; Tryptophan; Tryptophanase | 1988 |
Mechanistic deductions from kinetic isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Erwinia herbicola and Citrobacter freundii tyrosine phenol-lyase.
Topics: Alanine; Binding, Competitive; Citrobacter; Cysteine; Deuterium; Erwinia; Hydrogen-Ion Concentration; Kinetics; Lyases; Phenylalanine; Pyridoxal Phosphate; Tyrosine; Tyrosine Phenol-Lyase | 1988 |
Studies on Waldenström macroglobulins. 3. The conformation of immunoglobulin M investigated by infrared spectroscopy.
Topics: Amides; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Cysteine; Detergents; Deuterium; Electrophoresis; gamma-Globulins; Humans; Hydrogen-Ion Concentration; Immunoglobulins; Infrared Rays; Iodoacetates; Macroglobulins; Spectrophotometry; Sulfuric Acids; Waldenstrom Macroglobulinemia | 1971 |
Comparative studies on adrenal iron-sulfur protein and its selenium derivatives by electron nuclear double resonance.
Topics: Adrenal Glands; Animals; Apoproteins; Binding Sites; Cattle; Cysteine; Deuterium; Electron Spin Resonance Spectroscopy; Ferredoxins; Iron; Iron Isotopes; Isotopes; Protein Binding; Selenium; Sulfur | 1973 |
The mode of action of N-methyl-N'-nitro-N-nitrosoguanidine in mutagenesis. VII. The transfer of the methyl group of N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; Deuterium; DNA; DNA, Bacterial; Escherichia coli; Guanidines; Guanine; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Mutagens; Nitro Compounds; Nitroso Compounds; Nitrosoguanidines; Quaternary Ammonium Compounds; Thymus Gland | 1972 |
Cysteine-catalyzed hydrogen isotope exchange at the 5 position of uridylic acid.
Topics: Catalysis; Cysteine; Deuterium; Hydrogen; Isotope Labeling; Uracil Nucleotides | 1972 |
On the mode of activation of the catalytically essential sulfhydryl group of papain.
Topics: Acetamides; Acylation; Alkylation; Amides; Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Deuterium; Histidine; Hydrogen-Ion Concentration; Imidazoles; Iodoacetates; Kinetics; Papain; Sulfhydryl Compounds; X-Ray Diffraction | 1973 |
Cysteine-catalyzed hydrogen isotope exchange at position 5 of uridylic acid.
Topics: Amines; Catalysis; Cysteine; Deuterium; Isotope Labeling; Temperature; Uracil Nucleotides; Uridine | 1973 |
Synthesis of S-alkyl-L-cysteine from pyruvate, ammonia and alkyl-mercaptan by cysteine desulfhydrase of Aerobacter aerogenes.
Topics: Alkylation; Ammonia; Autoanalysis; Chromatography, Gel; Chromatography, Ion Exchange; Cystathionine; Cysteine; Deuterium; Electrophoresis, Polyacrylamide Gel; Enterobacter; Ethanol; Hydrogen-Ion Concentration; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Methanol; Molecular Weight; Pyruvates; Sulfhydryl Compounds; Time Factors | 1974 |
[Synthesis of 3,4-dihydro-3-amino-7-hydroxycoumarin from S-methyl-l-cysteine and resorcinol by crystalline-beta-tyrosinase].
Topics: Catechol Oxidase; Coumarins; Cysteine; Deuterium; Escherichia; Kinetics; Magnetic Resonance Spectroscopy; Resorcinols | 1970 |
Contact-shifted NMR of spinach ferredoxin: additional resonances and partial assignments.
Topics: Amino Acids; Cysteine; Deuterium; Ferredoxins; Iron; Magnetic Resonance Spectroscopy; Mathematics; Oxidation-Reduction; Plants | 1972 |
Cystathionine -synthase. Studies of hydrogen exchange reactions.
Topics: Alanine; Aminobutyrates; Catalysis; Chemical Phenomena; Chemistry; Cystathionine; Cysteine; Deuterium; Homoserine; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Salmonella; Serine; Succinates; Tritium | 1972 |
Dissociation constants of lanthionine and its structure in aqueous solution.
Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Chlorine; Computers; Cysteine; Deuterium; Dicarboxylic Acids; Hydrogen-Ion Concentration; Infrared Rays; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Nitrates; Optical Rotatory Dispersion; Potentiometry; Sodium; Spectrophotometry; Stereoisomerism; Sulfides; Temperature; Thermodynamics; Tosyl Compounds | 1971 |
The nature of general base-general acid catalysis in serine proteases.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Deuterium; Endopeptidases; Histidine; Kinetics; Models, Chemical; Models, Structural; Serine | 1969 |
Luminescence of the tryptophan and tyrosine residues of papain in solution.
Topics: Cold Temperature; Cysteine; Deuterium; Fluorescence; Glucose; Glycols; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Papain; Tryptophan; Tyrosine | 1970 |
Lysine 2,3-aminomutase. Purification and properties of a pyridoxal phosphate and S-adenosylmethionine-activated enzyme.
Topics: Acetone; Amino Acids; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Clostridium; Cysteine; Deuterium; Dialysis; Drug Stability; Electrophoresis; Electrophoresis, Disc; Enzyme Activation; Hydrogen-Ion Concentration; Hydroxylamines; Intramolecular Transferases; Iron; Isomerases; Isoniazid; Kinetics; Lysine; Methionine; Methods; Molecular Weight; Nucleosides; Pyridoxal Phosphate; Pyridoxine; Streptomycin; Sulfhydryl Compounds; Temperature; Tritium | 1970 |
Kinetic and structural studies of hydroxyproline 2-epimerase.
Topics: Amino Acids; Benzoates; Binding Sites; Chromatography, Gel; Cysteine; Deuterium; Electrophoresis, Disc; Enzyme Induction; Hydroxyproline; Isomerases; Kinetics; Magnetic Resonance Spectroscopy; Molecular Weight; Peptides; Pseudomonas; Sulfides; Trypsin; Ultracentrifugation | 1970 |
Biosynthesis of deuterated benzylpenicillins. I. Solvent deuterium oxide participation.
Topics: Cysteine; Deuterium; Infrared Rays; Magnetic Resonance Spectroscopy; Oxides; Penicillin G; Spectrophotometry; Valine | 1970 |
S methylation of thiols by O-methylisourea.
Topics: Acetates; Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Deuterium; Dipeptides; Ethanol; Glycine; Guanidines; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Mercaptoethanol; Methylation; Models, Biological; Sulfhydryl Compounds; Sulfhydryl Reagents; Time Factors; Urea | 1970 |
Essential histidyl residues of octopine dehydrogenase.
Topics: Animals; Carbonates; Cysteine; Deuterium; Dicarboxylic Acids; Guanidines; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; L-Lactate Dehydrogenase; Mollusca; Muscles; Oxidoreductases; Spectrophotometry; Tyrosine | 1971 |
Repair and damage by mercaptans in 60Co gamma-ray irradiation of organic compounds in aqueous solution.
Topics: 1-Propanol; Acetone; Catalysis; Chromatography, Gas; Cobalt Isotopes; Cysteine; Deuterium; Free Radicals; Hydrogen-Ion Concentration; Mercaptoethanol; Radiation Effects; Radiochemistry; Solutions; Spectrophotometry; Sulfhydryl Compounds; Water | 1971 |
Proton retention in the gamma-elimination reaction catalysed by cystathionine gamma-synthase.
Topics: Cysteine; Deuterium; Dinitrophenols; Hydrazines; Hydro-Lyases; Hydrogen; Keto Acids; Magnetic Resonance Spectroscopy; Protons; Pyridoxal Phosphate; Serine; Succinates; Tritium; Water | 1968 |
Metabolism of L-[sulfane-34S]thiocystine by Escherichia coli.
Topics: Cysteine; Cystine; Deuterium; Escherichia coli; Hydrogen Sulfide; Serine; Sulfur Isotopes | 1982 |
Metabolism of haloforms to carbon monoxide. IV. studies on the reaction mechanism in vivo.
Topics: Animals; Carbon Monoxide; Carcinogens; Chloroform; Cysteine; Deuterium; Hydrocarbons, Brominated; Male; Maleates; Phenobarbital; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Trihalomethanes | 1981 |
Solvent isotope effects on the rates of alkylation of thiolamine models of papain.
Topics: Alkylation; Binding Sites; Catalysis; Cysteine; Deuterium; Kinetics; Mercaptoethylamines; Models, Chemical; Papain; Solvents | 1980 |
Observation of a second substrate radical intermediate in the reaction of lysine 2,3-aminomutase: a radical centered on the beta-carbon of the alternative substrate, 4-thia-L-lysine.
Topics: Amino Acid Isomerases; Clostridium; Cysteine; Deuterium; Electrochemistry; Electron Spin Resonance Spectroscopy; Intramolecular Transferases; Kinetics; S-Adenosylmethionine; Substrate Specificity | 1995 |
Decreasing the basicity of the active site base, Lys-258, of Escherichia coli aspartate aminotransferase by replacement with gamma-thialysine.
Topics: Amino Acid Sequence; Aspartate Aminotransferases; Binding Sites; Cysteine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lysine; Mathematics; Mutagenesis, Site-Directed; Recombinant Proteins; Spectrophotometry; Structure-Activity Relationship; Thermodynamics | 1995 |
Electron paramagnetic resonance evidence for a cysteine-based radical in pyruvate formate-lyase inactivated with mercaptopyruvate.
Topics: Acetyltransferases; Binding Sites; Cysteine; Deuterium; Disulfides; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Kinetics; Recombinant Proteins; Sulfhydryl Compounds | 1995 |
Protein expression, selective isotopic labeling, and analysis of hyperfine-shifted NMR signals of Anabaena 7120 vegetative [2Fe-2S]ferredoxin.
Topics: Anabaena; Arginine; Bacterial Proteins; Base Sequence; Carbon Isotopes; Carrier Proteins; Cysteine; Deuterium; Ferredoxins; Isotope Labeling; Ligands; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nitrogen Isotopes; Recombinant Proteins | 1995 |
Hydrogen exchange of the glycyl radical of pyruvate formate-lyase is catalyzed by cysteine 419.
Topics: Acetyltransferases; Binding Sites; Cysteine; Deuterium; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Glycine; Hydrogen; Ion Exchange; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction | 1995 |
Measurement of excitatory sulfur amino acids, cysteine sulfinic acid, cysteic acid, homocysteine sulfinic acid, and homocysteic acid in serum by stable isotope dilution gas chromatography-mass spectrometry and selected ion monitoring.
Topics: Aspartic Acid; Cysteic Acid; Cysteine; Deuterium; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Isotope Labeling; Neurotransmitter Agents; Reference Values | 1994 |
Human placental aldose reductase: role of Cys-298 in substrate and inhibitor binding.
Topics: Aldehyde Reductase; Aldehydes; Circular Dichroism; Cysteine; Deuterium; Female; Humans; Imidazoles; Imidazolidines; Iodoacetates; Iodoacetic Acid; Kinetics; NADP; Naphthalenes; Placenta; Pregnancy; Quercetin; Spectrophotometry, Ultraviolet | 1994 |
Alternative model for mechanism-based inhibition of Escherichia coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine 5'-diphosphate.
Topics: Azides; Cysteine; Deoxyuracil Nucleotides; Deuterium; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Models, Chemical; Mutation; Nitrogen; Ribonucleotide Reductases; Spin Labels; Tyrosine | 1993 |
In Azotobacter vinelandii hydrogenase, substitution of serine for the cysteine residues at positions 62, 65, 294, and 297 in the small (HoxK) subunit affects H2 oxidation [corrected].
Topics: Amino Acid Sequence; Azotobacter vinelandii; Benzyl Viologen; Cysteine; Deuterium; Electron Transport; Hydrogen; Hydrogenase; Methylene Blue; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Phenotype | 1993 |
1H-NMR and 13C-NMR investigation of complexes of Mn2+ with ocytocin analogues in (2H6)dimethylsulfoxide.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Carbon Isotopes; Cysteine; Deuterium; Dimethyl Sulfoxide; Glutamine; Hydrogen; Magnetic Resonance Spectroscopy; Manganese; Models, Molecular; Molecular Sequence Data; Oxytocin; Proline; Protein Binding; Protein Conformation; Sarcosine; Sulfhydryl Compounds; Thermodynamics; Threonine | 1996 |
Structural characterization of an analog of the major rate-determining disulfide folding intermediate of bovine pancreatic ribonuclease A.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cattle; Cloning, Molecular; Computer Simulation; Crystallography, X-Ray; Cysteine; Deuterium; Disulfides; Entropy; Escherichia coli; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Pancreas; Polymerase Chain Reaction; Protein Conformation; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Ribonuclease, Pancreatic; Software; Thermodynamics | 1997 |
Solution structure of the antimicrobial peptide ranalexin and a study of its interaction with perdeuterated dodecylphosphocholine micelles.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Circular Dichroism; Cysteine; Deuterium; Escherichia coli; Magnetic Resonance Spectroscopy; Micelles; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Peptides, Cyclic; Phosphorylcholine; Protein Conformation; Protein Structure, Secondary; Rana catesbeiana; Skin; Solutions; Staphylococcus epidermidis; Trifluoroethanol; Water | 1998 |
Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate.
Topics: Alanine; Binding Sites; Circular Dichroism; Cysteine; Cysteine Synthase; Deuterium; Enzyme Activation; Enzyme Stability; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Insertional; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1998 |
Conformational and dynamic changes of Yersinia protein tyrosine phosphatase induced by ligand binding and active site mutation and revealed by H/D exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.
Topics: Amino Acid Sequence; Binding Sites; Cyclotrons; Cysteine; Deuterium; Endopeptidases; Hydrogen; Hydrolysis; Ligands; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; Protein Conformation; Protein Tyrosine Phosphatases; Serine; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Threonine; Yersinia | 1998 |
Kinetic mechanism of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase.
Topics: Amino Acid Substitution; Animals; Binding Sites; Cysteine; Deuterium; Humans; IMP Dehydrogenase; Kinetics; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Mycophenolic Acid; NAD; Protein Binding; Serine; Spectrometry, Fluorescence; Thermodynamics; Tritrichomonas foetus | 1999 |
Catalytic acid/base residues of glutamate racemase.
Topics: Amino Acid Isomerases; Amino Acids; Catalysis; Cysteine; Deuterium; Glutamates; Hydrogen-Ion Concentration; Kinetics; Lactobacillus; Mutagenesis, Site-Directed; Serine; Stereoisomerism | 1999 |
Mechanism of 3-methylaspartase probed using deuterium and solvent isotope effects and active-site directed reagents: identification of an essential cysteine residue.
Topics: Ammonia; Ammonia-Lyases; Binding Sites; Chromatography, High Pressure Liquid; Cysteine; Deuterium; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Kinetics; Magnesium; Models, Chemical; Models, Molecular; Protein Conformation; Time Factors | 1999 |
Electron-nuclear interactions in two prototypical [2Fe-2S] proteins: selective (chiral) deuteration and analysis of (1)H and (2)H NMR signals from the alpha and beta hydrogens of cysteinyl residues that ligate the iron in the active sites of human ferredo
Topics: Anabaena; Binding Sites; Carbon-Oxygen Lyases; Cysteine; Deuterium; Electrons; Escherichia coli; Ferredoxins; Humans; Hydrogen; Iron-Sulfur Proteins; Magnetic Resonance Spectroscopy; Models, Molecular; Plant Proteins; Protein Conformation; Recombinant Proteins | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Mutational analysis of metallo-beta-lactamase CcrA from Bacteroides fragilis.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Bacterial Proteins; Bacteroides fragilis; beta-Lactamases; Cysteine; Deuterium; DNA Mutational Analysis; DNA, Bacterial; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Kinetics; Metalloproteins; Mutagenesis, Site-Directed; Protons; Recombinant Proteins; Serine; Solvents; Zinc | 2000 |
The asparagine-stabilized beta-turn of apamin: contribution to structural stability from dynamics simulation and amide hydrogen exchange analysis.
Topics: Amides; Amino Acid Sequence; Amino Acid Substitution; Animals; Apamin; Asparagine; Cysteine; Deuterium; Disulfides; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peptides; Protein Conformation; Protein Structure, Secondary; Thermodynamics | 2000 |
Identification of active site residues in E. coli ketopantoate reductase by mutagenesis and chemical rescue.
Topics: Acetic Acid; Alanine; Alcohol Oxidoreductases; Alkylation; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Cysteine; Deuterium; Escherichia coli; Formates; Gene Expression Regulation, Bacterial; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Pantothenic Acid; Recombinant Proteins; Sequence Alignment; Substrate Specificity | 2000 |
ESEEM and mims ENDOR spectroscopies of cis,trans-(L-N2S2)MoVO(SCH2Ph): detection of the two benzylthiolate alpha protons.
Topics: Animals; Binding Sites; Chickens; Cysteine; Desulfovibrio; Deuterium; Electron Spin Resonance Spectroscopy; Eukaryota; Liver; Molybdenum; Nitrate Reductase; Nitrate Reductases; Oxidoreductases Acting on Sulfur Group Donors; Paracoccus; Plants | 2000 |
Requirement of glutathione and cysteine in guanine-specific oxidation of DNA by carcinogenic potassium bromate.
Topics: Animals; Antineoplastic Agents; Bromates; Carcinogens; Cell Transformation, Neoplastic; Cysteine; Deuterium; DNA Damage; Food Additives; Free Radicals; Genes, p53; Genes, ras; Glutathione; Guanine; HL-60 Cells; Humans; Kidney Neoplasms; Rats; Spin Trapping | 2001 |
Intramolecular interactions in chemically modified Escherichia coli thioredoxin monitored by hydrogen/deuterium exchange and electrospray ionization mass spectrometry.
Topics: Alkylation; Chromatography, High Pressure Liquid; Cysteine; Deuterium; Escherichia coli; Glutathione; Hydrogen; Kinetics; Oxidation-Reduction; Peptide Fragments; Protein Conformation; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Thioredoxins | 2001 |
Hydrogenases in the "active" state: determination of g-matrix axes and electron spin distribution at the active site by 1H ENDOR spectroscopy.
Topics: Binding Sites; Computer Simulation; Cysteine; Deuterium; Electron Spin Resonance Spectroscopy; Electrons; Hydrogenase; Iron; Models, Molecular; Nickel; Proteobacteria; Protons; Selenium; Spectrum Analysis; Sulfur | 2002 |
Hydrogen/deuterium exchange and mass spectrometric analysis of a protein containing multiple disulfide bonds: Solution structure of recombinant macrophage colony stimulating factor-beta (rhM-CSFbeta).
Topics: Amino Acid Sequence; Cysteine; Deuterium; Disulfides; Humans; Hydrogen; Macrophage Colony-Stimulating Factor; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Peptides; Protein Conformation; Protein Subunits; Recombinant Proteins; Solvents; Time Factors | 2002 |
Conformational analysis of intermediates involved in the in vitro folding pathways of recombinant human macrophage colony stimulating factor beta by sulfhydryl group trapping and hydrogen/deuterium pulsed labeling.
Topics: Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine; Deuterium; Dimerization; Disulfides; Humans; Kinetics; Macrophage Colony-Stimulating Factor; Oxidation-Reduction; Peptide Mapping; Protein Conformation; Protein Denaturation; Protein Folding; Protons; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds | 2002 |
The unusual catalytic triad of poliovirus protease 3C.
Topics: 3C Viral Proteases; Catalysis; Catalytic Domain; Cysteine; Cysteine Endopeptidases; Deuterium; Glutamic Acid; Glutamine; Glycine; Hydrogen-Ion Concentration; Kinetics; Methionine; Models, Chemical; Mutagenesis, Site-Directed; Poliovirus; Serine; Solvents; Substrate Specificity; Temperature; Thermodynamics; Viral Proteins | 2003 |
Analysis of the effect of potato carboxypeptidase inhibitor pro-sequence on the folding of the mature protein.
Topics: Amino Acid Sequence; Carboxypeptidases; Circular Dichroism; Cysteine; Deuterium; Enzyme Precursors; Escherichia coli; Kinetics; Leucyl Aminopeptidase; Molecular Sequence Data; Mutagenesis; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peptide Fragments; Plant Proteins; Protease Inhibitors; Protein Denaturation; Protein Folding; Protein Renaturation; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2003 |
IRON REQUIREMENT FOR THE HYDROGENASE OF DESULFOVIBRIO DESULFURICANS.
Topics: Coumarins; Cysteine; Desulfovibrio; Desulfovibrio desulfuricans; Deuterium; Hydrogenase; Iron; Metabolism; Oxidoreductases | 1964 |
Direct determination of the interleukin-6 binding epitope of the interleukin-6 receptor by NMR spectroscopy.
Topics: Binding Sites; Cloning, Molecular; Conserved Sequence; Cysteine; Deuterium; Escherichia coli; Interleukin-6; Magnetic Resonance Spectroscopy; Models, Molecular; Nitrogen Isotopes; Protein Conformation; Receptors, Interleukin-6; Recombinant Proteins | 2004 |
A new deuterated alkylating agent for quantitative proteomics.
Topics: Alkylating Agents; Alkylation; Amino Acid Sequence; Animals; Cattle; Cysteine; Deuterium; Humans; Hydrogen-Ion Concentration; Isotope Labeling; Molecular Sequence Data; Molecular Weight; Muramidase; Proteins; Proteomics; Surface-Active Agents | 2003 |
Probing the mechanism of hamster arylamine N-acetyltransferase 2 acetylation by active site modification, site-directed mutagenesis, and pre-steady state and steady state kinetic studies.
Topics: Acetamides; Acetyl Coenzyme A; Acetylation; Alkylating Agents; Amino Acid Sequence; Amino Acid Substitution; Animals; Arylamine N-Acetyltransferase; Binding Sites; Cricetinae; Cysteine; Deuterium; Enzyme Inhibitors; Hydrogen-Ion Concentration; Iodoacetamide; Isoenzymes; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrophenols; Papain; Protein Conformation; Recombinant Proteins | 2004 |
Evidence for accelerated rates of glutathione utilization and glutathione depletion in adolescents with poorly controlled type 1 diabetes.
Topics: Adolescent; Blood Glucose; Body Size; Cysteine; Deuterium; Diabetes Mellitus, Type 1; Erythrocytes; Female; Glutathione; Humans; Infusions, Intravenous; Male; Radioisotope Dilution Technique; Reference Values | 2005 |
Resonance assignments and secondary structureof hPrxVI, a 25 kDa 1-cys human peroxiredoxin enzyme.
Topics: Amino Acid Sequence; Asparagine; Carbon Isotopes; Cysteine; Deuterium; Escherichia coli; Glycine; Humans; Molecular Sequence Data; Molecular Weight; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peroxidases; Peroxiredoxins; Protein Structure, Secondary; Protons | 2005 |
Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides; Biophysics; Cysteine; Deuterium; Deuterium Oxide; Electron Spin Resonance Spectroscopy; Lipids; Magnetics; Models, Chemical; Models, Statistical; Molecular Sequence Data; Nitric Oxide; Ovum; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Protein Structure, Tertiary; Spin Labels; Temperature; Time Factors | 2006 |
Accelerated on-column lysine derivatization and cysteine methylation by imidazole reaction in a deuterated environment for enhanced product ion analysis.
Topics: Amino Acid Sequence; Cysteine; Deuterium; Erythropoietin; Humans; Imidazoles; Interferon alpha-2; Interferon-alpha; Lysine; Metalloendopeptidases; Methylation; Molecular Sequence Data; Molecular Structure; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Trypsin | 2006 |
Methionine kinetics are altered in the elderly both in the basal state and after vaccination.
Topics: Adult; Aged; Aging; Carbon Isotopes; Cysteine; Deuterium; Female; Homocysteine; Humans; Inflammation; Isotope Labeling; Male; Mathematics; Methionine; Methylation; Nutritional Requirements; Postprandial Period; Vaccination | 2006 |
Knots in rings. The circular knotted protein Momordica cochinchinensis trypsin inhibitor-II folds via a stable two-disulfide intermediate.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cattle; Chromatography, High Pressure Liquid; Cyclotides; Cysteine; Deuterium; Disulfides; Hydrogen; In Vitro Techniques; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Chaperones; Molecular Conformation; Molecular Sequence Data; Oxygen; Plant Proteins; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Spectrometry, Mass, Electrospray Ionization; Trypsin; Trypsin Inhibitors | 2006 |
Quantitative analysis of acrylamide labeled serum proteins by LC-MS/MS.
Topics: Acrylamides; Algorithms; Alkylation; Amino Acid Sequence; Blood Proteins; Carbon Radioisotopes; Chromatography, Liquid; Cysteine; Deuterium; Humans; Mass Spectrometry; Molecular Sequence Data | 2006 |
Mass spectrometry-based glycoproteomic approach involving lysine derivatization for structural characterization of recombinant human erythropoietin.
Topics: Amino Acid Sequence; Cysteine; Deuterium; Erythropoietin; Glycoproteins; Glycosylation; Humans; Lysine; Molecular Sequence Data; Peptide Fragments; Polysaccharides; Proteomics; Recombinant Proteins; Trypsin | 2006 |
Catalytic mechanism of Zn2+-dependent polyol dehydrogenases: kinetic comparison of sheep liver sorbitol dehydrogenase with wild-type and Glu154-->Cys forms of yeast xylitol dehydrogenase.
Topics: Animals; Cysteine; D-Xylulose Reductase; Deuterium; Enzyme Inhibitors; Fungal Proteins; Glutamic Acid; Humans; Hydrogen-Ion Concentration; L-Iditol 2-Dehydrogenase; Liver; Molecular Structure; NAD; Oxidation-Reduction; Point Mutation; Sheep; Solvents; Sorbitol; Zinc | 2007 |
Are carboxyl groups the most acidic sites in amino acids? Gas-phase acidity, H/D exchange experiments, and computations on cysteine and its conjugate base.
Topics: Acids; Amino Acids; Benzyl Alcohol; Cysteine; Deuterium; Fourier Analysis; Gases; Hydrogen; Hydrogen Bonding; Mass Spectrometry; Molecular Conformation; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds | 2007 |
Toward a property/function relationship for metallothioneins: histidine coordination and unusual cluster composition in a zinc-metallothionein from plants.
Topics: Amino Acid Sequence; Cysteine; Databases, Protein; Deuterium; Histidine; Metallothionein; Plant Proteins; Sequence Alignment; Sequence Homology, Amino Acid | 2007 |
A novel pyrimidine-based stable-isotope labeling reagent and its application to quantitative analysis using matrix-assisted laser desorption/ionization mass spectrometry.
Topics: Animals; Chickens; Cysteine; Deuterium; Hydrogen-Ion Concentration; Isotope Labeling; Muramidase; Peptides; Proteins; Pyrimidines; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin | 2007 |
Isotope-coded, iodoacetamide-based reagent to determine individual cysteine pK(a) values by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Topics: Acetanilides; Cysteine; Deuterium; Hydrogen-Ion Concentration; Indicators and Reagents; Iodoacetamide; Isotopes; Kinetics; Oxidation-Reduction; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Thioredoxins; Titrimetry | 2008 |
Quantification of cysteine S-conjugate of 3-sulfanylhexan-1-ol in must and wine of petite arvine vine by stable isotope dilution analysis.
Topics: Cysteine; Deuterium; Fermentation; Fruit; Hexanols; Indicator Dilution Techniques; Sulfhydryl Compounds; Vitis; Wine | 2008 |
Gas-phase fragmentation of long-lived cysteine radical cations formed via NO loss from protonated S-nitrosocysteine.
Topics: Cations; Cysteine; Deuterium; Gases; Isomerism; Models, Chemical; Nitrites; Protons; S-Nitrosoglutathione; S-Nitrosothiols; Spectrometry, Mass, Electrospray Ionization; Thermodynamics | 2009 |
Detection of the sulfhydryl groups in proteins with slow hydrogen exchange rates and determination of their proton/deuteron fractionation factors using the deuterium-induced effects on the 13C(beta) NMR signals.
Topics: Carbon Isotopes; Cysteine; Deuterium; Hydrogen; Nuclear Magnetic Resonance, Biomolecular; Proteins; Protons | 2010 |
Excretion of 2,3-dihydroxy-propionamide (OH-PA), the hydrolysis product of glycidamide, in human urine after single oral dose of deuterium-labeled acrylamide.
Topics: Acetamides; Acetylcysteine; Acrylamide; Adult; Amides; Analytic Sample Preparation Methods; Carcinogens; Cysteine; Deuterium; Epoxy Compounds; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Indicators and Reagents; Male; Organosilicon Compounds; Oxidation-Reduction; Silanes; Sulfoxides; Trifluoroacetic Acid | 2011 |
Unique cyanide adduct in human serum albumin: potential as a surrogate exposure marker.
Topics: Biomarkers; Chromatography, High Pressure Liquid; Cyanides; Cysteine; Deuterium; Disulfides; Humans; Peptides; Serum Albumin; Tandem Mass Spectrometry | 2011 |
Specific racemization of heavy-chain cysteine-220 in the hinge region of immunoglobulin gamma 1 as a possible cause of degradation during storage.
Topics: Amino Acid Sequence; Cysteine; Deuterium; Humans; Hydrogen-Ion Concentration; Hydrolysis; Immunoglobulin G; Peptide Mapping; Tandem Mass Spectrometry; Temperature; Time Factors | 2011 |
Conformational analysis by quantitative NOE measurements of the β-proton pairs across individual disulfide bonds in proteins.
Topics: Animals; Cattle; Cysteine; Deuterium; Disulfides; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Protons; Trypsin Inhibitors | 2012 |
Isotope-coded protein label.
Topics: Animals; Carbon Isotopes; Chemical Precipitation; Cysteine; Data Interpretation, Statistical; Deuterium; Electrophoresis, Gel, Two-Dimensional; Humans; Isotope Labeling; Mass Spectrometry; Methylation; Peptide Fragments; Proteolysis; Proteome; Reference Standards; Serine Endopeptidases; Software; Succinimides | 2012 |
An approach for triplex-isobaric peptide termini labeling (triplex-IPTL).
Topics: Apoptosis; Carbon Isotopes; Cell Cycle Checkpoints; Cysteine; Deuterium; HeLa Cells; Humans; Isotope Labeling; Peptides; Tandem Mass Spectrometry | 2013 |
Syntheses of deuterium labeled prenyldiphosphate and prenylcysteine analogues for in vivo mass spectrometric quantification.
Topics: Cysteine; Deuterium; Isotope Labeling; Mass Spectrometry; Polyisoprenyl Phosphates | 2013 |
Sequence-specific formation of d-amino acids in a monoclonal antibody during light exposure.
Topics: Amino Acids; Antibodies, Monoclonal; Chromatography, High Pressure Liquid; Cysteine; Deuterium; Deuterium Exchange Measurement; Disulfides; Humans; Hydrogen; Hydrogen Bonding; Light; Peptide Fragments; Photolysis; Tandem Mass Spectrometry | 2014 |
Human DNMT1 transition state structure.
Topics: Binding, Competitive; Carbon Isotopes; Carbon Radioisotopes; Catalysis; Cysteine; Cytosine; Deuterium; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Humans; Kinetics; Models, Molecular; Protein Structure, Tertiary; Recombinant Fusion Proteins; S-Adenosylhomocysteine; Tritium | 2016 |