deuterium has been researched along with cotinine in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benowitz, NL; Jacob, P; Wilson, M; Yu, L | 1 |
| Benowitz, NL; Jacob, P; Shulgin, AT | 1 |
| Benowitz, NL; Jacob, P | 2 |
| Baines, J; Warwick, PM | 1 |
| Benowitz, NL; Herrera, B; Jacob, P; Pérez-Stable, EJ | 1 |
| Berlanga, Mdel R; Garcia, C; Hernandez, J; Salazar, G | 1 |
| Benowitz, NL; Gourlay, SG; Hukkanen, J; Kenkare, S | 1 |
| Benowitz, NL; Jacob, P; Lessov-Schlaggar, CN; Swan, GE | 1 |
| Benowitz, NL; Jacob, P; Lessov-Schlaggar, CN; Swan, GE; Tyndale, RF | 1 |
| Benowitz, NL; Hukkanen, J; Jacob, P | 1 |
| Benowitz, NL; Dempsey, DA; Levi, M; Sheiner, LB | 1 |
| Benowitz, NL; Krasnow, RE; Lessov-Schlaggar, CN; Mwenifumbo, JC; Swan, GE; Tyndale, RF; Zhou, Q | 1 |
| Ho, SW; Murphy, SE; Villalta, P; von Weymarn, LB | 1 |
| Andrews, JA; Benowitz, N; Bergen, AW; He, Y; Hops, H; Lessov-Schlaggar, CN; Swan, GE; Tildesley, E; Webster, C | 1 |
| Bawazeer, S; Knottenbelt, C; Watson, DG | 1 |
| Benowitz, NL; Moscicki, AB; Rait, MA; Rubinstein, ML; Sen, S; Shiffman, S | 1 |
| Benowitz, NL; Dempsey, DA; Fuentes-Afflick, E; Hoffmann, E; Jacob, P; Sambol, NC; Tyndale, RF | 1 |
5 trial(s) available for deuterium and cotinine
| Article | Year |
|---|---|
Female sex and oral contraceptive use accelerate nicotine metabolism.
Topics: Adolescent; Adult; Aged; Area Under Curve; Cohort Studies; Contraceptives, Oral, Hormonal; Cotinine; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Menopause; Metabolic Clearance Rate; Middle Aged; Nicotine; Sex Factors; Smoking; Twins | 2006 |
CYP2A6 genotype and the metabolism and disposition kinetics of nicotine.
Topics: Adolescent; Adult; Aged; Alleles; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cotinine; Cytochrome P-450 CYP2A6; Deuterium; Dose-Response Relationship, Drug; Ganglionic Stimulants; Gene Frequency; Glucuronides; Half-Life; Humans; Infusions, Intravenous; Isoenzymes; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Nicotine; Polymorphism, Genetic; Time Factors; Twins | 2006 |
Effect of grapefruit juice on cytochrome P450 2A6 and nicotine renal clearance.
Topics: Administration, Oral; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Beverages; Citrus paradisi; Cotinine; Cytochrome P-450 CYP2A6; Deuterium; Female; Ganglionic Stimulants; Glucuronides; Half-Life; Humans; Kidney; Liver; Male; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Nicotine | 2006 |
Population pharmacokinetics of nicotine and its metabolites I. Model development.
Topics: Administration, Oral; Adult; Aryl Hydrocarbon Hydroxylases; Biological Availability; Biotransformation; Cotinine; Cytochrome P-450 CYP2A6; Deuterium; Female; Half-Life; Humans; Liver; Male; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Models, Biological; Models, Statistical; Nicotine; Nicotinic Agonists; Population Surveillance; Predictive Value of Tests; Reference Values; Saliva | 2007 |
Identification of novel CYP2A6*1B variants: the CYP2A6*1B allele is associated with faster in vivo nicotine metabolism.
Topics: 3' Flanking Region; Aryl Hydrocarbon Hydroxylases; Base Sequence; Biotransformation; Cotinine; Cytochrome P-450 CYP2A6; Deuterium; Gene Frequency; Genetic Linkage; Genotype; Glucuronates; Humans; Infusions, Intravenous; Mixed Function Oxygenases; Molecular Sequence Data; Nicotine; Nicotinic Agonists; Phenotype; Polymorphism, Genetic; Sequence Alignment; Substrate Specificity | 2008 |
13 other study(ies) available for deuterium and cotinine
| Article | Year |
|---|---|
Selected ion monitoring method for determination of nicotine, cotinine and deuterium-labeled analogs: absence of an isotope effect in the clearance of (S)-nicotine-3',3'-d2 in humans.
Topics: Adult; Cotinine; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Nicotine; Smoking | 1991 |
Recent studies of nicotine metabolism in humans.
Topics: Adult; Cotinine; Deuterium; Humans; Infusions, Intravenous; Male; Nicotine; Smoking | 1988 |
Metabolism of nicotine to cotinine studied by a dual stable isotope method.
Topics: Adult; Cotinine; Deuterium; Female; Humans; Male; Middle Aged; Nicotine; Oxidation-Reduction; Smoking | 1994 |
Nicotine and cotinine elimination pharmacokinetics in smokers and nonsmokers.
Topics: Adult; Cotinine; Deuterium; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Nicotine; Regression Analysis; Smoking | 1993 |
Energy expenditure in free-living smokers and nonsmokers: comparison between factorial, intake-balance, and doubly labeled water measures.
Topics: Adult; Anthropometry; Basal Metabolism; Body Composition; Body Water; Cotinine; Deuterium; Diet; Energy Intake; Energy Metabolism; Factor Analysis, Statistical; Female; Humans; Male; Oxygen Isotopes; Smoking | 1996 |
Nicotine metabolism and intake in black and white smokers.
Topics: Adult; Area Under Curve; Black People; Chromatography, Thin Layer; Cotinine; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Humans; Infusions, Intravenous; Linear Models; Male; Nicotine; Smoking; White People | 1998 |
Maternal smoking effects on infant growth.
Topics: Adult; Birth Weight; Body Height; Body Weight; Cadmium; Copper; Cotinine; Deuterium; Hair; Humans; Infant; Infant, Newborn; Iron; Lactation; Longitudinal Studies; Maternal Behavior; Milk, Human; Smoking; Tobacco Smoke Pollution; Zinc | 2002 |
Influence of menstrual cycle on cytochrome P450 2A6 activity and cardiovascular effects of nicotine.
Topics: Adrenocorticotropic Hormone; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Blood Pressure; Cardiovascular Agents; Clinical Trials as Topic; Cotinine; Cytochrome P-450 CYP2A6; Deuterium; Epinephrine; Estradiol; Female; Follicular Phase; Heart Rate; Humans; Infusions, Intravenous; Luteal Phase; Mixed Function Oxygenases; Nicotine; Norepinephrine; Progesterone | 2005 |
Analysis of [3',3'-d(2)]-nicotine and [3',3'-d(2)]-cotinine by capillary liquid chromatography-electrospray tandem mass spectrometry.
Topics: Administration, Oral; Biomarkers; Calibration; Capillary Electrochromatography; Chromatography, High Pressure Liquid; Cotinine; Deuterium; Humans; Injections, Intravenous; Molecular Structure; Nicotine; Radioactive Tracers; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Smoking; Smoking Cessation; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2007 |
Genome-wide linkage of cotinine pharmacokinetics suggests candidate regions on chromosomes 9 and 11.
Topics: Adolescent; Child; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cotinine; Deuterium; Female; Genome-Wide Association Study; Humans; Indicators and Reagents; Male; Nicotine | 2009 |
Determination of nicotine exposure in dogs subjected to passive smoking using methanol extraction of hair followed by hydrophilic interaction chromatography in combination with Fourier transform mass spectrometry.
Topics: Animals; Calibration; Chemical Fractionation; Chromatography, Liquid; Cotinine; Deuterium; Dogs; Hair; Hydrophobic and Hydrophilic Interactions; Methanol; Nicotine; Oxidation-Reduction; Sodium Hydroxide; Solvents; Sonication; Spectroscopy, Fourier Transform Infrared; Tobacco Smoke Pollution | 2012 |
Nicotine metabolism and addiction among adolescent smokers.
Topics: Adolescent; Behavior, Addictive; Chromatography, Liquid; Cotinine; Deuterium; Female; Humans; Male; Prospective Studies; Saliva; Self Report; Smoking; Tandem Mass Spectrometry; Tobacco Use Disorder | 2013 |
CYP2A6 genotype but not age determines cotinine half-life in infants and children.
Topics: Age Factors; Aryl Hydrocarbon Hydroxylases; Black or African American; Child; Child, Preschool; Cotinine; Cytochrome P-450 CYP2A6; Deuterium; Genotype; Half-Life; Hispanic or Latino; Humans; Infant; Tobacco Smoke Pollution; White People | 2013 |