Page last updated: 2024-08-22

deuterium and carbamazepine

deuterium has been researched along with carbamazepine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bertilsson, L; Osterloh, J1
Browne, TR; Perchalski, RJ; Pylilo, RJ; Szabo, GK1
Baillie, TA; Boberg, M; Rettenmeier, AW; Rettie, AE1
Bertilsson, L; Höjer, B; Osterloh, J; Rane, A; Tybring, G1
Browne, TR; Davoudi, H; Josephs, EG; Szabo, GK1
Ajami, A; Browne, HK; Josephs, EG; Szabo, GK1
Busch, W; Gläser, HR; Knöller, K; Möder, M; Osenbrück, K; Reinstorf, F; Schirmer, M; Strauch, G; Weise, SM; Wennrich, R1
Dansette, PM; Defoy, D; Klarskov, K; Neugebauer, W; Wagner, JR1

Trials

1 trial(s) available for deuterium and carbamazepine

ArticleYear
Determination of pharmacokinetic drug interactions with carbamazepine and phenytoin using stable isotope labeling and simple high-performance liquid chromatography/ultraviolet detection technique.
    Neurology, 1994, Volume: 44, Issue:12

    Topics: Administration, Oral; Analysis of Variance; Carbamazepine; Chromatography, High Pressure Liquid; Deuterium; Drug Interactions; Humans; Isotope Labeling; Metabolic Clearance Rate; Phenytoin; Spectrophotometry, Ultraviolet

1994

Other Studies

7 other study(ies) available for deuterium and carbamazepine

ArticleYear
The absence of isotopic effect during the elimination of deuterium labelled carbamazepine in the rat.
    Life sciences, 1978, Jul-03, Volume: 23, Issue:1

    Topics: Animals; Carbamazepine; Deuterium; Gas Chromatography-Mass Spectrometry; Half-Life; Isotope Labeling; Male; Rats; Time Factors

1978
Simultaneous separation and determination (in serum) of phenytoin and carbamazepine and their deuterated analogues by high-performance liquid chromatography--ultraviolet detection for tracer studies.
    Journal of chromatography, 1990, Dec-28, Volume: 535, Issue:1-2

    Topics: Carbamazepine; Chromatography, High Pressure Liquid; Deuterium; Humans; Phenytoin; Ultraviolet Rays

1990
Cytochrome P-450-catalyzed desaturation of valproic acid in vitro. Species differences, induction effects, and mechanistic studies.
    The Journal of biological chemistry, 1988, Sep-25, Volume: 263, Issue:27

    Topics: Animals; Carbamazepine; Cytochrome P-450 Enzyme System; Deuterium; Enzyme Induction; Fatty Acids, Monounsaturated; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Phenobarbital; Phenytoin; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Valproic Acid

1988
Autoinduction of carbamazepine metabolism in children examined by a stable isotope technique.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:1

    Topics: Adolescent; Carbamazepine; Child; Deuterium; Epilepsy; Female; Humans; Kinetics; Male

1980
Alternatives to least squares linear regression analysis for computation of standard curves for quantitation by high performance liquid chromatography: applications to clinical pharmacology.
    Journal of clinical pharmacology, 1994, Volume: 34, Issue:3

    Topics: Analysis of Variance; Carbamazepine; Chromatography, High Pressure Liquid; Deuterium; Humans; Least-Squares Analysis; Pharmacology, Clinical; Phenytoin; Reference Values; Regression Analysis

1994
Sources and transport of selected organic micropollutants in urban groundwater underlying the city of Halle (Saale), Germany.
    Water research, 2007, Volume: 41, Issue:15

    Topics: Benzhydryl Compounds; Benzopyrans; Boron; Carbamazepine; Cities; Deuterium; Environmental Monitoring; Germany; Oxygen Isotopes; Phenols; Sulfates; Sulfur Isotopes; Water Movements; Water Pollutants, Chemical; Water Supply

2007
Evaluation of deuterium labeled and unlabeled bis-methyl glutathione combined with nanoliquid chromatography-mass spectrometry to screen and characterize reactive drug metabolites.
    Chemical research in toxicology, 2011, Mar-21, Volume: 24, Issue:3

    Topics: Acetaminophen; Animals; Carbamazepine; Chromatography, High Pressure Liquid; Deuterium; Deuterium Exchange Measurement; Esterification; Glutathione; Isotope Labeling; Male; Microsomes; NADP; Nanotechnology; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization

2011