Page last updated: 2024-08-22

deuterium and androstenedione

deuterium has been researched along with androstenedione in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199012 (48.00)18.7374
1990's8 (32.00)18.2507
2000's4 (16.00)29.6817
2010's1 (4.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dyer, RL; Harrow, TA1
Marquet, A; Viger, A1
Homoki, J; Shackleton, CH; Teller, WM; Wachter, UA; Wudy, SA1
Numazawa, M; Osawa, Y; Satoh, S1
Mildvan, AS; Talalay, P; Xue, LA1
Cox, J; Dumasia, MC; Gower, DB; Houghton, E; Marshall, D; Smith, SJ; Teale, P1
Kosaki, T; Ohnishi, S; Osawa, Y1
Furuta, T; Kasuya, Y; Kusano, K1
Hashino, M; Kosaki, T; Nakayama, T; Ohigashi, S; Ohnishi, S; Osawa, Y; Yanaihara, T; Yarborough, C1
Arunachalam, T; Caspi, E; Njar, VC; Spiteller, G1
Pasanen, M1
Cox, LW; Johnson, DW; McEvoy, M; Phillipou, G; Seamark, RF1
Braselton, WE; Engel, LL; Orr, JC2
Cornforth, JW; Eggerer, H; Messner, B; Phillips, GT1
Alfsen, A; Baulieu, EE; Weintraub, H1
Johnson, DW; Phillipou, G; Seamark, RF1
Brodie, AM; Brodie, HJ; Marsh, DA; Romanoff, L; Williams, KI1
Coustal, S; Marquet, A; Viger, A1
Blotny, G; Hawkinson, DC; Pollack, RM; Zawrotny, ME1
Andrade, LC; da Silva, EJ; de Almeida, MJ; Neves, AS; Paixão, JA; Roleira, FM; Sá e Melo, ML; Silva, MR1
Nagaoka, M; Numazawa, M1
Handa, W; Matsuzaki, H; Numazawa, M1
Furuta, T; Kasuya, Y; Omori, Y; Shibasaki, H; Shinohara, Y; Yamamoto, K; Yokokawa, A1
Bernhardt, R; Khatri, Y; Kiss, FM; Zapp, J1

Reviews

1 review(s) available for deuterium and androstenedione

ArticleYear
Deuterium labelled steroid hormones: syntheses and application in quantitation and endocrinology.
    Journal of steroid biochemistry, 1981, Volume: 14, Issue:8

    Topics: Androstenedione; Chemical Phenomena; Chemistry; Dehydroepiandrosterone; Deuterium; Estradiol; Estriol; Estrogens; Estrone; Ethinyl Estradiol; Female; Gas Chromatography-Mass Spectrometry; Glucuronates; Gonadal Steroid Hormones; Humans; Hydroxytestosterones; Isotope Labeling; Male; Pregnancy; Pregnanediones; Pregnenolone; Progesterone; Progestins; Testosterone

1981

Other Studies

24 other study(ies) available for deuterium and androstenedione

ArticleYear
Synthesis of C-19 deuterium labelled steroids.
    Steroids, 1979, Volume: 33, Issue:6

    Topics: Androstenedione; Chemical Phenomena; Chemistry; Deuterium; Isotope Labeling; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrophotometry, Infrared

1979
A reinvestigation of the mechanism of Pseudomonas testosteroni delta 5-3-ketosteroid isomerase.
    Biochimica et biophysica acta, 1977, Dec-08, Volume: 485, Issue:2

    Topics: Androstenedione; Deuterium; Isomerases; Isotope Labeling; Pseudomonas; Steroid Isomerases

1977
Androgen metabolism assessment by routine gas chromatography/mass spectrometry profiling of plasma steroids: Part 1, Unconjugated steroids.
    Steroids, 1992, Volume: 57, Issue:7

    Topics: 17-alpha-Hydroxyprogesterone; Androgens; Androstane-3,17-diol; Androstenedione; Child; Dehydroepiandrosterone; Deuterium; Dihydrotestosterone; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyprogesterones; Male; Testosterone

1992
Synthesis of deuterium-labeled 16 alpha,19-dihydroxy C19 steroids as internal standards for gas chromatography-mass spectrometry.
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:10

    Topics: Androstenedione; Deuterium; Gas Chromatography-Mass Spectrometry

1992
Studies of the catalytic mechanism of an active-site mutant (Y14F) of delta 5-3-ketosteroid isomerase by kinetic deuterium isotope effects.
    Biochemistry, 1991, Nov-12, Volume: 30, Issue:45

    Topics: Amino Acid Sequence; Androstenedione; Binding Sites; Catalysis; Deuterium; Kinetics; Models, Theoretical; Mutagenesis, Site-Directed; Pseudomonas; Radioisotope Dilution Technique; Recombinant Proteins; Solvents; Steroid Isomerases; Thermodynamics

1991
The use of stable isotopes and gas chromatography/mass spectrometry in the identification of steroid metabolites in the equine.
    Steroids, 1990, Volume: 55, Issue:10

    Topics: Allantois; Androgens; Androstenediol; Androstenedione; Animals; Chorion; Dehydroepiandrosterone; Deuterium; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Horses; Isotope Labeling; Male; Nandrolone; Placenta; Pregnancy; Testis; Testosterone

1990
Synthesis of 19-hydroxy-[7-2H2]androstenedione for human metabolism studies.
    Steroids, 1990, Volume: 55, Issue:1

    Topics: Androstenediol; Androstenedione; Deuterium; Female; Humans; Pregnancy

1990
Simultaneous measurements of endogenous and deuterium-labelled tracer variants of androstenedione and testosterone by capillary gas chromatography-mass spectrometry.
    Journal of chromatography, 1990, Jan-26, Volume: 525, Issue:1

    Topics: Androstenedione; Calibration; Deuterium; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Humans; Testosterone

1990
Serum level of 19-hydroxyandrostenedione during pregnancy and at delivery determined by gas chromatography/mass spectrometry.
    Steroids, 1990, Volume: 55, Issue:4

    Topics: Androstenedione; Deuterium; Female; Fetal Blood; Gas Chromatography-Mass Spectrometry; Humans; Labor, Obstetric; Male; Placenta; Pregnancy; Reference Standards; Steroids

1990
Synthesis of c-2, 3, 17 and 19-oxygenated androgens.
    Journal of steroid biochemistry, 1988, Volume: 29, Issue:3

    Topics: Acetates; Acetic Acid; Androgens; Androstenedione; Borohydrides; Chemical Phenomena; Chemistry; Chromatography; Deuterium; Magnetic Resonance Spectroscopy; Organometallic Compounds; Tritium

1988
Human placental aromatase activity: use of a C18 reversed-phase cartridge for separation of tritiated water or steroid metabolites in placentas from both smoking and non-smoking mothers in vitro.
    Biological research in pregnancy and perinatology, 1985, Volume: 6, Issue:2

    Topics: Androstenedione; Aromatase; Aryl Hydrocarbon Hydroxylases; Chromatography, Thin Layer; Deuterium; Female; Humans; Oxidoreductases; Placenta; Pregnancy; Smoking

1985
Deuterium labelled steroid hormones: tracers for the measurement of androgen plasma clearance rates in women.
    Journal of steroid biochemistry, 1985, Volume: 22, Issue:3

    Topics: Androgens; Androstenedione; Anorexia Nervosa; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Hirsutism; Humans; Isotope Labeling; Menopause; Metabolic Clearance Rate; Obesity; Polycystic Ovary Syndrome; Testosterone

1985
The flux of intermediates and products in aromatizaton of C19 steroids by human placental microsomes.
    European journal of biochemistry, 1974, Oct-01, Volume: 48, Issue:1

    Topics: Androstenedione; Androstenols; Biotransformation; Carbon Radioisotopes; Deuterium; Estradiol; Estrone; Female; Humans; Hydroxysteroid Dehydrogenases; Microsomes; NADP; Placenta; Pregnancy; Temperature; Testosterone; Time Factors

1974
Substrate stereochemistry of 3-hydroxy-3-methylglutaryl-coenzyme A synthase.
    European journal of biochemistry, 1974, Mar-01, Volume: 42, Issue:2

    Topics: Acetates; Androstenedione; Animals; Binding Sites; Biological Assay; Carbon Radioisotopes; Cholesterol; Chromatography, Paper; Coenzyme A; Deuterium; Electrophoresis, Paper; Glutarates; Isotope Labeling; Kinetics; Lactobacillus; Liver; Mevalonic Acid; Mycobacterium; Oxo-Acid-Lyases; Protein Binding; Rats; Saccharomyces cerevisiae; Squalene; Stereoisomerism; Tritium

1974
The twin ion technique for detection of metabolites by gas chromatography-mass spectrometry: intermediates in estrogen biosynthesis.
    Analytical biochemistry, 1973, Volume: 53, Issue:1

    Topics: 17-Ketosteroids; Androgens; Androstenedione; Androstenes; Carbon Isotopes; Chromatography, Gas; Chromatography, Gel; Chromatography, Thin Layer; Deuterium; Estradiol; Estrogens; Estrone; Female; Humans; Hydroxysteroids; Ketosteroids; Mass Spectrometry; Methods; Microsomes; Placenta; Pregnancy; Testosterone

1973
Influence of the position of the double bond in steroid substrates on the efficiency of the proton-transfer reaction by Pseudomonas testosteroni 3-oxo-steroid delta 4-delta 5-isomerase.
    The Biochemical journal, 1980, Mar-01, Volume: 185, Issue:3

    Topics: Androstenedione; Deuterium; Isomerases; Isomerism; Kinetics; Models, Biological; Protons; Pseudomonas; Steroid Isomerases; Steroids; Structure-Activity Relationship

1980
Synthesis of deuterium- and tritium-labelled 4-hydroxyandrostene-3,17-dione, an aromatase inhibitor, and its metabolism in vitro and in vivo in the rat.
    Biochemical pharmacology, 1982, Mar-01, Volume: 31, Issue:5

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Deuterium; Female; In Vitro Techniques; Oxidoreductases; Rats; Tritium

1982
A reinvestigation of the mechanism of delta 5-3-ketosteroid isomerase from bovine adrenal glands.
    Biochimica et biophysica acta, 1981, Aug-13, Volume: 660, Issue:2

    Topics: Adrenal Glands; Androstenedione; Animals; Cattle; Deuterium; Hydrogen-Ion Concentration; Isomerases; Microsomes; Pseudomonas; Steroid Isomerases

1981
Mechanism of proton transfer in the isomerization of 5-androstene-3, 17-dione by 3-oxo-delta 5-steroid isomerase and its D38E mutant.
    Biochemistry, 1996, May-21, Volume: 35, Issue:20

    Topics: Androstenedione; Deuterium; Magnetic Resonance Spectroscopy; Mass Spectrometry; Point Mutation; Protons; Stereoisomerism; Steroid Isomerases

1996
X-ray and deuterium labeling studies on the abnormal ring cleavages of a 5 beta-epoxide precursor of formestane.
    Steroids, 2002, Volume: 67, Issue:3-4

    Topics: Androstanols; Androstenedione; Androstenes; Antineoplastic Agents; Aromatase Inhibitors; Deuterium; Enzyme Inhibitors; Isomerism; Isotope Labeling; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; X-Rays

2002
Gas chromatography-mass spectrometric analysis of oxidative reactions of [19,19-(2)H(2)]19-hydroxy-3-deoxy androgens by placental aromatase. bsence of a deuterium-isotope effect.
    Steroids, 2005, Volume: 70, Issue:12

    Topics: Androgens; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Humans; Oxidation-Reduction; Placenta; Pregnancy

2005
Biochemical aromatization of 2-methyleneandrostenedione: stereochemistry of hydrogen removal at the C-1 position.
    The Journal of steroid biochemistry and molecular biology, 2006, Volume: 101, Issue:4-5

    Topics: Androstenedione; Aromatase Inhibitors; Deuterium; Hydrogen; Isomerism; Molecular Conformation; Molecular Structure

2006
Simultaneous determination of androstenedione, 11beta-hydroxyandrostenedione, and testosterone in human plasma by stable isotope dilution mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Mar-01, Volume: 877, Issue:7

    Topics: Androstenedione; Carbon Isotopes; Deuterium; Humans; Mass Spectrometry; Testosterone

2009
Identification of new substrates for the CYP106A1-mediated 11-oxidation and investigation of the reaction mechanism.
    FEBS letters, 2015, Aug-19, Volume: 589, Issue:18

    Topics: Androstenedione; Bacillus megaterium; Cytochrome P-450 Enzyme System; Deuterium; Kinetics; Oxidation-Reduction; Protein Binding; Solvents; Substrate Specificity

2015