deuterium has been researched along with alanine in 156 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 64 (41.03) | 18.7374 |
| 1990's | 32 (20.51) | 18.2507 |
| 2000's | 42 (26.92) | 29.6817 |
| 2010's | 15 (9.62) | 24.3611 |
| 2020's | 3 (1.92) | 2.80 |
| Authors | Studies |
|---|---|
| Bright, HJ; Porter, DJ; Voet, JG | 1 |
| Cheung, YF; Kaczorowski, GJ; Walsh, C | 1 |
| Hvidt, A; Junager, F; Sorup, P | 1 |
| Cronholm, T | 1 |
| Arnold, KJ; Bier, DM; Holland, WH; Holmes, WF; Kipnis, DM; Sherman, WR | 1 |
| Babu, UM; Johnston, RB; McNeff, LC | 1 |
| Barash, L; Kollonitsch, J | 1 |
| Babu, UM; Johnston, RB | 2 |
| Master, BS; Roeder, SB; Stewart, CJ | 1 |
| Cooper, AJ | 1 |
| Denu, JM; Fitzpatrick, PF | 2 |
| Aubrey, KL; Thomas, GJ | 1 |
| Celma, C; Giralt, E | 1 |
| Miasoedov, NF; Rozenberg, SG; Zaĭtsev, DA; Zaloznykh, VM; Zolotarev, IuA | 1 |
| Lim, VS; Tsalikian, E | 1 |
| Kiick, DM; Phillips, RS | 2 |
| Chiasson, JL | 1 |
| Chiasson, JL; Falardeau, P; Lecavalier, L; Martineau, A | 1 |
| Abeles, RH; Krodel, E; Massey, V; Walsh, CT | 1 |
| Nishikimi, M; Oishi, N; Takai, A; Yagi, K | 1 |
| Bruice, TC; Shinkai, S | 1 |
| Johns, RB; Looney, FD; Whelan, DJ | 1 |
| Johns, RB; Seuret, MG | 1 |
| Nishikimi, M; Oishi, N; Yagi, K | 1 |
| Abeles, RH; Schonbrunn, A; Walsh, CT | 1 |
| Grathwohl, C; Wüthrich, K | 1 |
| Abbott, EH; Tenenbaum, SW; Witherup, TH | 1 |
| Faulstich, H; Heber, H; Wieland, T | 1 |
| Bier, DM; Craig, JC; Gruenke, LD | 1 |
| Bukald, NE; Hirshfield, IN | 1 |
| Christensen, HN; Quay, S | 1 |
| Asquith, RS; Carthew, P | 1 |
| Kortt, AA; Liu, TY | 1 |
| Klein, MP; Llinás, M; Neilands, JB | 1 |
| Dreeskamp, H; Nicolau, C; Schulte-Frohlinde, D | 1 |
| Dimicoli, JL; Hélène, C | 1 |
| De Vries, AL; Lin, Y; Shier, WT | 1 |
| Blout, ER; Visser, L | 1 |
| Flavin, M; Posner, BI | 1 |
| Fanconi, B; Peticolas, WL; Small, EW | 1 |
| Faulstich, H; Goodman, M; Naider, F; Patel, DJ; Tonelli, AE; Wieland, T | 1 |
| Chadha, MS; Lawless, JG | 1 |
| Stapleton, IW; Weber, OA | 1 |
| Brewer, HB; Bronzert, TJ; Fales, HM; Milne, GW; Nagai, Y; Pisano, JJ | 1 |
| Crespi, HL; Daboll, HF; Katz, JJ | 1 |
| Bruice, TC; Maley, JR | 1 |
| Cohen, JS; Putter, I; Smith, JL; Vandenheuvel, WJ | 1 |
| Malcolm, BR | 1 |
| Dugas, H; Kaplan, H; Symonds, VB; Whitaker, DR | 1 |
| Miller, WG | 1 |
| Boeck, LD; Gorman, M; Neuss, N; Shah, R | 1 |
| Sheard, B; Shulman, RG; Yamane, T | 1 |
| Applequist, J; Glickson, JD | 1 |
| Prescott, DJ; Rabinowitz, JL | 1 |
| Ayling, JE; Dunathan, HC; Snell, EE | 1 |
| Calf, GE; Garnett, JL; Halpern, BH; Turnbull, K | 1 |
| Jenkins, WT; Saier, MH | 1 |
| Mossoba, MM; Riesz, P; Rosenthal, I | 1 |
| Gerich, JE; Haymond, MW; Miles, JM; Nissen, SL | 1 |
| Bier, DM; Lo, C; Matthews, DE; Yang, RD; Young, VR | 1 |
| Cleland, WW; Cook, PF; Grimshaw, CE | 1 |
| Dye, JL; June, DS; Suelter, CH | 1 |
| Manning, JM; Soper, TS | 1 |
| Kallen, R; Walsh, C; Wang, EA | 1 |
| Batchelder, LS; Jelinski, LW; Sullivan, CE; Torchia, DA | 1 |
| Jelinski, LW; Sullivan, CE; Torchia, DA | 1 |
| Du, Y; LaVelle, JM; Mangold, JB; Mischke, MR | 1 |
| Abeygunawardana, C; Johnson, MO; Mori, S; van Zijl, PC | 1 |
| Abuaf, PA; Corkum, N; Crowther, JB; Goldstein, G; Goodlett, DR; Kowalski, KA; Mukherjee, TK; Savage, PA; Tolan, JW | 1 |
| Cerdán, S; Erhard, P; Moldes, M; Seelig, J | 1 |
| Biesemans, M; Malaisse, WJ; Willem, R | 1 |
| Burrin, DG; Frazer, M; Jahoor, F; Reeds, PJ | 1 |
| Ghisla, S; Langkau, B; Pilone, MS; Pollegioni, L; Tischer, W | 1 |
| Alberti, KG; Ansiferov, M; Branch, W; Brown, M; Davis, SN; Hales, CN; Hetherington, C; Monti, L; Orskov, H; Piatti, PM | 1 |
| Alberti, KG; Antsiferov, M; Brown, M; Davis, SN; Hales, CN; Hetherington, C; Monti, L; Orskov, H; Piatti, PM; Sobey, W | 1 |
| Olson, GT; Silverman, RB | 1 |
| Gaggelli, E; Grzonka, Z; Kasprzykowski, F; Kozlowski, H; Maccotta, A; Valensin, G | 1 |
| Halstead, TK; Keenan, RD; Williams, MA | 1 |
| Adler, G; Albuszies, G; Beckh, KH; Ensinger, H; Geisser, W; Georgieff, M; Schricker, T; Weidenbach, H | 1 |
| Bourque, J; Chiasson, JL; Ducros, F; Langelier, H; Lavoie, C | 1 |
| Cosma, A; Curti, B; Mattevi, A; Mazzeo, D; Todone, F; Vanoni, MA | 1 |
| Bourque, J; Chiasson, JL; Ducros, F; el Achkar, GG; Maheux, P | 1 |
| Ackermans, MT; Chandramouli, V; Dekker, E; Ekberg, K; Kager, PA; Landau, BR; Romijn, JA; Sauerwein, HP; Thuy, LT; Van Thien, H; Wahren, J | 1 |
| Dekker, E; Endert, E; Hellerstein, MK; Marsh, K; Neese, RA; Peshu, N; Romijn, JA; Sauerwein, HP | 1 |
| Subramanian, R; Webb, AG | 1 |
| Cook, PF; Kim, SK; Kredich, NM; Nalabolu, SR; Rege, VD; Schnackerz, KD; Tai, CH; Yoon, MY | 1 |
| Gloge, A; Langer, B; Poppe, L; Rétey, J | 1 |
| Pagliassotti, MJ; Podolin, DA; Wei, Y | 1 |
| Overman, SA; Thomas, GJ | 1 |
| Lehoux, IE; Mitra, B | 1 |
| Jemielity, J; Kańska, M; Lewandowicz, A; Paneth, P; Zoń, J | 1 |
| Greathouse, DV; Jude, AR; Koeppe, RE; Leister, MC | 1 |
| Ro, HS; Wilson Miles, E | 1 |
| Dagnelie, PC; Hordijk-Luijk, CH; Leij-Halfwerk, S; van Den Berg, JW; Wattimena, JD; Wilson, JP | 1 |
| Sack, I; Vega, S | 1 |
| Evans, PR; Leadlay, PF; Thomä, NH | 1 |
| Ferry, JG; Tripp, BC | 1 |
| Blanchard, JS; Zheng, R | 1 |
| Chen, X; Dieckmann, T; Jin, X; Medhekar, R; Toney, MD; Zhou, X | 1 |
| Guengerich, FP; Miller, GP; Yun, CH | 1 |
| Bagwell, C; Banik, U; Dunn, MF; Hur, O; Miles, EW; Weber-Ban, E; Yang, LH | 1 |
| Arabshahi, A; Berger, E; Frey, PA; Schilling, JF; Wei, Y | 1 |
| Dunn, MF; Ferrari, D; Miles, EW; Yang, LH | 1 |
| Epand, RF; Epand, RM; Martin, I; Ruysschaert, JM | 1 |
| Ghisla, S; Harris, CM; Pollegioni, L | 1 |
| Stein, RL; Thomas, B; Wang, Y | 1 |
| Bowler, BE; Kise, KJ | 1 |
| Battiste, JL; Li, R; Woodward, C | 1 |
| Ammatuna, M; Battezzati, A; Caumo, A; Coppa, J; Fattorini, A; Luzi, L; Mazzaferro, V; Regalia, E; Romito, R; Sereni, LP | 1 |
| Larsen, TM; Poyner, RR; Reed, GH; Wong, SW | 1 |
| Bader, R; Beck-Sickinger, AG; Lerch, M; Rytz, G; Zerbe, O | 1 |
| Kallenbach, NR; Olson, CA; Shi, Z; Sosnick, TR | 1 |
| Cook, PF; Daum, S; Tai, CH | 1 |
| Cegelski, L; Mehta, AK; O'Connor, RD; Schaefer, J | 1 |
| Grage, SL; Watts, A; Watts, JA | 1 |
| Malaisse, WJ; Willem, R | 1 |
| Carpenter, MR; Cotter, PD; Hill, C; Martin, NI; Ross, RP; Sprules, T; Vederas, JC | 1 |
| Malthouse, JP; Níbeilliú, ME | 1 |
| Kavanagh, KL; Kratzer, R; Nidetzky, B; Wilson, DK | 1 |
| Spies, MA; Toney, MD; Watnik, MR; Woodward, JJ | 1 |
| Aisenbrey, C; Bechinger, B | 2 |
| Badaloo, A; Forrester, T; Heird, WC; Jahoor, F; Reid, M | 1 |
| Albuquerque, CP; Chen, SH; Kolodner, RD; Schmidt, KH; Smolka, MB; Wei, XX; Zhou, H | 1 |
| Burton, IW; Driedzic, WR; Ewart, KV; Short, CE; Walter, JA | 1 |
| Corcelli, SA; Cremeens, ME; Kinnaman, CS; Romesberg, FE | 1 |
| Glaubitz, C; Hellmich, UA; Lehner, I; Lopez, JJ; Siarheyeva, A; van Veen, HW | 1 |
| Bubb, WA; Chapman, BE; Kuchel, PW; Naumann, C | 1 |
| Argyriou, DN; Bordallo, HN; de Souza, JM; Freire, PT | 1 |
| Arnett, SO; Gerratana, B; Townsend, CA | 1 |
| Abraham, A; Bodenhausen, G; Cavadini, S | 1 |
| Bolon, D; Deshaies, RJ; Fushman, D; Haririnia, A; Purohit, N; Twarog, MZ; Verma, R | 1 |
| Ahn, C; Hardin, DS; Rice, J; Rice, M; Rosenblatt, R | 1 |
| Ayala, I; Boisbouvier, J; Gans, P; Sounier, R; Usé, N | 1 |
| Heuser, JA; Pacey, GE; Spendel, WU; Taulbee, AR | 1 |
| Kay, LE; Ruschak, AM | 1 |
| Im, W; Jo, S; Kim, T | 1 |
| Potapov, A; Thurber, KR; Tycko, R; Yau, WM | 1 |
| Barbie, P; Huo, L; Kazmaier, U; Müller, R | 1 |
| Holland, GP; Shi, X; Yarger, JL | 1 |
| Bodenhausen, G; Chan-Huot, M; Duchambon, P; Duma, L; Lesot, P; Pelupessy, P; Reddy, UV; Suryaprakash, N; Toney, MD | 1 |
| Csonka, R; Kaizer, J; Sabolović, J; Speier, G; Szalontai, G | 1 |
| Chin, J; Moozeh, K; So, SM | 1 |
| Bodenhausen, G; Bornet, A; Canet, E; de Nanteuil, F; Flamm, A; Gossert, AD; Jannin, S; Ji, X; Konrat, R; Kurzbach, D; Miéville, P; Milani, J; Vuichoud, B; Weber, E | 1 |
| Greathouse, DV; Koeppe, RE; Rajagopalan, V | 1 |
| Collins, M; Doddridge, A; Salouros, H | 1 |
| Igarashi, S; Imai, S; Inoue, M; Itoh, H; Kofuku, Y; Mizukoshi, T; Nakata, K; Natsume, M; Shimada, I; Shiraishi, Y; Suzuki, EI; Ueda, T; Yamaguchi, H; Yokomizo, T | 1 |
| Aristizabal Henao, JJ; Bazinet, RP; Chalil, D; Hopperton, KE; Kitson, AP; Lacombe, RJS; Masoodi, M; Metherel, AH; Morin-Rivron, D; Stark, KD | 1 |
| Funk, AM; Hever, T; Khemtong, C; Malloy, CR; Maptue, NR; Sherry, AD; Wen, X | 1 |
| Bechshoeft, RL; Blomstrand, E; Dideriksen, K; Doessing, S; Holm, L; Højfeldt, G; Moberg, M; Nielsen, RH; Reitelseder, S; van Hall, G | 1 |
| Abdelkader, EH; Adekanmi, AJ; Adeyinka, AO; Afkari, BF; Agarwal, A; Aggelopoulos, S; Ai, G; Akiyama, T; Alcalde, MP; Aljohani, AI; Almeida, SCG; Alrefai-Kirkpatrick, R; Amri, M; An, S; Andreo, JC; Angelidi, AM; Anjos, D; Araujo, AC; Arena, A; Arif, MS; Bai, C; Bai, D; Ball, GR; Banerjee, BD; Barraviera, B; Becker, ME; Berdagué, P; Biswas, NR; Blair, RV; Borges, MASB; Brownell, EA; Buchaim, DV; Buchaim, RL; Bueno, CRS; Butler, EL; Buxó, M; Cao, Y; Carias, AM; Carson, TL; Casabona, J; Caterino-de-Araujo, A; Chang, HW; Chaudhary, E; Chauhan, K; Chen, C; Chen, F; Chen, J; Chen, K; Chen, LN; Chen, Q; Chen, Y; Chin, C; Cho, H; Christidis, P; Cleveland, LM; Colombo, D; Comolatti, R; Conti, F; Cook, AC; Coward, K; Crawford, AD; Cui, H; Cuyàs, E; da Fonseca, SG; Dadashi, M; Danish, S; Deng, C; Deorari, AK; Desai, R; Detregiachi, CRP; Devlin, AM; Dhanoya, T; Di Carlo, M; Díaz, Y; Ding, ZJ; Dong, S; Doyle, M; Doyle-Meyers, LA; Du, X; Duarte, MAH; El-Sharawy, KA; Engelward, BP; Espinoza, I; Fabre, A; Faggioli, P; Faisaluddin, M; Fan, CL; Ferreira, RS; Fiaccadori, FS; Fiocchi, M; Fong, HK; Foti, R; Franco, FC; Frassi, M; Fujimori, A; Fukasawa, LO; Fusaro, E; Ganesh, D; Gao, F; Gaur, A; Geetha, J; Geng, D; Geng, S; Gonçalves, MG; Gouilleux, B; Green, AR; Greiver, M; Grembiale, RD; Guggino, G; Guilarde, AO; Gupta, YK; Hafner, SM; He, H; He, YX; Henderson, AM; Herath, ID; Hirakawa, H; Hirota, S; Holzman, C; Hope, TJ; Hu, K; Huang, B; Huang, F; Huang, L; Huang, PY; Hultquist, JF; Iannone, F; Immel, S; Ioannidis, O; Jakiemiec, BE; Jia, X; Jiang, D; Jin, H; Jindal, S; Jones, C; Juel, BE; Kashir, J; Kawazu, R; Khodulev, VI; Kleer, CG; Kotidis, E; Kumar, G; Kumar, S; Kuninobu, Y; Kurapaty, C; Lee, MJ; Lei, ZY; Lemos, APS; Lesot, P; Li, M; Li, S; Li, W; Li, X; Li, Y; Liang, Y; Liao, YC; Limonta, M; Liu, C; Liu, JS; Liu, Q; Liu, X; Lomater, C; Lorenzo-Redondo, R; Loutzidou, L; Luo, L; Luo, X; Lupu, R; Ma, G; Ma, Q; Madden, PJ; Maleckis, A; Mancini, J; Mansoori, K; Mantzoros, I; Marchesoni, A; Margerison, CE; Mariano, GP; Mariorakis, C; Martinelli, E; Martinou, EG; Masuzawa, T; McGlothen-Bell, K; McGrath, JM; McRaven, MD; Medico, PD; Menendez, JA; Midkiff, CC; Miro, JM; Mirza, S; Moller-Levet, CS; Mondelli, B; Morgan, KM; Morhason-Bello, IO; Morse, AL; Morton, K; Moslemkhani, C; Mukherjee, M; Namvar, MA; Nelson, RK; Nenoi, M; Ngai, YF; Nickoloff, JA; Nishida, T; Noll, M; Nomah, DK; Orsenigo, R; Otting, G; Ouzounidis, N; Pan, L; Panagiotopoulos, C; Park, CH; Patel, S; Patel, U; Perricone, R; Pomini, KT; Ponomarev, VV; Pramateftakis, MG; Prasad, P; Puttini, PCS; Quan, JY; Rademaker, A; Raffeiner, B; Rakha, EA; Recto, P; Reggelin, M; Reis, CHB; Ren, B; Reyes-Urueña, J; Reynolds, C; Ribeiro, BM; Rizzoli, S; Roberts, A; Roncari, B; Sacchi, CT; Sachdeva, R; Sai, S; Saikia, D; Sakthivadivel, V; Saltarelli, WA; Samer, S; Sangam, S; Scott, L; Servian, CDP; Shang, X; Shi, LZ; Shih, IA; Simons, LM; Singh, RP; Singh, S; Souza, M; Stepanova, JI; Sterner, NJ; Storm, JF; Su, X; Suzuki, M; Takahashi, T; Talge, NM; Tang, X; Teixeira, DB; Thomas, Y; Thon, S; Tian, CY; Tipre, M; Tirri, E; Torigoe, T; Toss, MS; Tripathi, A; Tsalis, K; Tworek, C; Vander Steen, T; Veazey, RS; Velpandian, T; Venugopal, PD; Verdura, S; Viapiana, O; Villinger, FJ; Vita, S; Vivanco-Hidalgo, RM; Walker, WJ; Wang, B; Wang, C; Wang, H; Wang, J; Wang, L; Wang, S; Wang, X; Wang, Y; Wei, L; Wen, Y; Wiedeman, AM; Wiley, E; Wintemute, K; Wu, C; Wu, J; Wu, S; Wu, W; Xiang, W; Xiao, S; Xiong, W; Xiong, Z; Xu, J; Xu, NS; Yang, J; Yang, Z; Ye, L; Ye, WC; You, HL; Yu, LZ; Zagni, E; Zamani-Hank, Y; Zhan, S; Zhang, J; Zhang, L; Zhang, X; Zhang, Y; Zhang, Z; Zhao, K; Zhao, L; Zhao, Z; Zheng, J; Zheng, X; Zheng, YR; Zhou, J; Zhu, M; Zhu, Q; Zou, C; Zou, S | 1 |
| Atherton, PJ; Bass, JJ; Davies, RW; Jakeman, PM; Kozior, M; Lynch, AE; Smith, K | 1 |
| Munakata, K; Nakagawa, M; Sumi, K; Yamada, K; Yoshida, N | 1 |
2 review(s) available for deuterium and alanine
| Article | Year |
|---|---|
Methyl groups as probes of supra-molecular structure, dynamics and function.
Topics: Alanine; Deuterium; Isotope Labeling; Keto Acids; Methionine; Methylation; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Recombinant Proteins | 2010 |
Topics: Alanine; Alkaloids; Amides; Animals; Anti-Inflammatory Agents; Antiviral Agents; Cyclization; Dammaranes; Deuterium; Electric Power Supplies; Electrolytes; Fluorine; Graphite; Humans; Ions; Isoindoles; Isotopes; Leucine; Light; Liquid Crystals; Lithium; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Nanocomposites; Panax; Panax notoginseng; Plant Roots; Plasma Gases; Polymers; Porphyrins; Proteins; Quantum Dots; Reproducibility of Results; Saponins; Triterpenes; Valine; Water; Zebrafish; Zinc | 2023 |
3 trial(s) available for deuterium and alanine
| Article | Year |
|---|---|
The effects of subcutaneous human proinsulin on the production of 64/65 split proinsulin, glucose turnover and intermediary metabolism in non-insulin-dependent diabetic man.
Topics: Alanine; Blood Glucose; Deuterium; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucose Clamp Technique; Glycerol; Humans; Insulin; Kinetics; Lactates; Male; Middle Aged; Proinsulin; Pyruvates; Radioisotope Dilution Technique | 1993 |
Weight loss and elevated gluconeogenesis from alanine in lung cancer patients.
Topics: Aged; Alanine; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; Cross-Sectional Studies; Deuterium; Female; Glucagon; Gluconeogenesis; Glucose; Humans; Insulin; Lung Neoplasms; Male; Middle Aged; Weight Loss | 2000 |
The Effect of Fava Bean (
Topics: Adult; Alanine; Deuterium; Eating; Female; Humans; Male; Muscle, Skeletal; Resistance Training; Vicia faba | 2022 |
151 other study(ies) available for deuterium and alanine
| Article | Year |
|---|---|
Mechanistic features of the D-amino acid oxidase reaction studied by double stopped flow spectrophotometry.
Topics: Alanine; Benzoates; D-Amino-Acid Oxidase; Deuterium; Kinetics; Light; ortho-Aminobenzoates; Oxidation-Reduction; Phenylalanine; Spectrophotometry; Structure-Activity Relationship | 1977 |
Substrate kinetic isotope effects in dehydrogenase coupled active transport in membrane vesicles of Escherichia coli.
Topics: Alanine; Amino Acids; Azotobacter; Biological Transport, Active; Cell Membrane; D-Amino-Acid Oxidase; Deuterium; Escherichia coli; Isotope Labeling; Kinetics; Onium Compounds; Species Specificity; Succinate Dehydrogenase; Succinates; Trityl Compounds | 1977 |
Physicochemical studies of a branched polypeptide antigen: poly(L-Tyr,L-Glu)-poly(DL-Ala)--poly(L-Lys).
Topics: Alanine; Antigens; Deuterium; Epitopes; Glutamates; Hydrogen; Hydrogen-Ion Concentration; Isoelectric Point; Lysine; Peptides; Protein Conformation; Spectrophotometry, Infrared; Structure-Activity Relationship; Tyrosine; Viscosity | 1977 |
Incorporation of the hydrogen atoms of ethanol into amino acids in rat liver in vivo.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chemical Phenomena; Chemistry; Deuterium; Ethanol; Female; Glutamates; Hydrogen; Liver; NAD; Proline; Rats | 1979 |
In-vivo measurement of glucose and alanine metabolism with stable isotopic tracers.
Topics: Alanine; Animals; Carbon Isotopes; Chromatography, Gas; Deuterium; Dogs; Glucose; Humans; Male; Mass Spectrometry; Radioisotope Dilution Technique; Radioisotopes | 1977 |
A general NMR method for the assay of racemase activity with optically active or optically inactive substrates.
Topics: Alanine; Bacillus subtilis; Deuterium; Glycine; Isomerases; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Optical Rotation; Stereoisomerism | 1975 |
Organofluorine synthesis via photofluorination: 3-fluoro-D-alanine and 2-deuterio analogue, antibacterials related to the bacterial cell wall.
Topics: Alanine; Anti-Infective Agents; Binding Sites; Cell Wall; Deuterium; Fluorine; Humans; Microbial Sensitivity Tests; Photochemistry | 1976 |
Nuclear magnetic resonance studies of D2O-substrate exchange reactions catalyzed by glutamic pyruvic and glutamic oxaloacetic transaminases.
Topics: Alanine; Deuterium; Magnetic Resonance Spectroscopy | 1976 |
13C NMR or coenzyme A and its constituent moieties.
Topics: Adenosine Diphosphate; Alanine; Carbon Isotopes; Coenzyme A; Cystamine; Cysteamine; Deuterium; Disulfides; Lactones; Magnetic Resonance Spectroscopy; Mercaptoethylamines; Pantetheine; Pantothenic Acid; Protein Conformation | 1975 |
Proton magnetic resonance studies of glutamate-alanine transaminase-catalyzed deuterium exchange. Evidence for proton conservation during prototropic transfer from the alpha carbon of L-alanine to the C4-position of pyridoxal 5'-phosphate.
Topics: Alanine; Alanine Transaminase; Binding Sites; Chemical Phenomena; Chemistry; Deuterium; Fourier Analysis; Kinetics; Magnetic Resonance Spectroscopy; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Temperature | 1976 |
pH and kinetic isotope effects on the reductive half-reaction of D-amino acid oxidase.
Topics: Alanine; D-Amino-Acid Oxidase; Deuterium; Glycine; Hydrogen-Ion Concentration; Isotope Labeling; Kinetics; Mathematics; Models, Theoretical; Serine | 1992 |
Raman spectroscopy of filamentous bacteriophage Ff (fd, M13, f1) incorporating specifically-deuterated alanine and tryptophan side chains. Assignments and structural interpretation.
Topics: Alanine; Capsid; Coliphages; Deuterium; DNA, Bacterial; DNA, Single-Stranded; DNA, Viral; Nucleic Acid Conformation; Protein Conformation; Spectrum Analysis, Raman; Tryptophan | 1991 |
Determination of the enantiomeric purity of synthetic peptides by gas chromatography-mass spectrometry.
Topics: Acetates; Alanine; Amino Acid Sequence; Amino Acids; Deuterium; Esters; Fenclonine; Gas Chromatography-Mass Spectrometry; Hydrolysis; Indicators and Reagents; Isotope Labeling; Molecular Sequence Data; Peptides; Proline; Stereoisomerism | 1991 |
[Analysis of highly tritium-labeled alanine using 3H- and 1H-NMR].
Topics: Alanine; Deuterium; Magnetic Resonance Spectroscopy; Tritium | 1990 |
L-triiodothyronine at a slightly over physiologic dose increases leucine flux, which suggests an increase in protein degradation in normal subjects.
Topics: Adult; Alanine; Deuterium; Female; Humans; Kinetics; Leucine; Male; Middle Aged; Nitrogen; Nitrogen Isotopes; Thyrotropin; Thyroxine; Triiodothyronine | 1989 |
Mechanistic deductions from multiple kinetic and solvent deuterium isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Escherichia coli tryptophan indole-lyase.
Topics: Alanine; Binding, Competitive; Catalysis; Cysteine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lyases; Oxindoles; Pyridoxal Phosphate; Solvents; Tryptophan; Tryptophanase | 1988 |
Mechanistic deductions from kinetic isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Erwinia herbicola and Citrobacter freundii tyrosine phenol-lyase.
Topics: Alanine; Binding, Competitive; Citrobacter; Cysteine; Deuterium; Erwinia; Hydrogen-Ion Concentration; Kinetics; Lyases; Phenylalanine; Pyridoxal Phosphate; Tyrosine; Tyrosine Phenol-Lyase | 1988 |
[Use of stable isotopes for studying the metabolism of energy substrates in man].
Topics: Alanine; Carbon Isotopes; Deuterium; Energy Metabolism; Gluconeogenesis; Glucose; Humans | 1988 |
Simultaneous determination of glucose turnover, alanine turnover, and gluconeogenesis in human using a double stable-isotope-labeled tracer infusion and gas chromatography-mass spectrometry analysis.
Topics: Alanine; Blood Glucose; Carbon Isotopes; Deuterium; Gas Chromatography-Mass Spectrometry; Gluconeogenesis; Glucose; Humans; Isotope Labeling; Kinetics; Radioisotope Dilution Technique; Tritium | 1985 |
Studies on the elimination reaction of D-amino acid oxidase with -amino- -chlorobutyrate. Further evidence for abstraction of substrate -hydrogen as a proton.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Apoproteins; Catalysis; Chlorine; D-Amino-Acid Oxidase; Deuterium; Hydrogen; Isomerism; Keto Acids; Kidney; Kinetics; Osmolar Concentration; Oxidation-Reduction; Oxygen Consumption; Protons; Serine; Spectrophotometry; Swine; Temperature; Threonine; Tritium | 1973 |
Mechanism of enzyme action. VI. Kinetic isotope effect on D-amino acid oxidase reaction.
Topics: Alanine; Aminobutyrates; Anaerobiosis; D-Amino-Acid Oxidase; Deuterium; Isotope Labeling; Kinetics; Leucine; Macromolecular Substances; Mathematics; Oscillometry; Oxygen Consumption; Protein Binding; Spectrophotometry; Time Factors; Valine | 1973 |
D2O-alanine exchange reactions catalyzed by alanine racemase and glutamic pyruvic transminase.
Topics: Alanine; Amino Acid Isomerases; Aspartate Aminotransferases; Bacillus subtilis; Chromatography, Gel; Chromatography, Ion Exchange; Deuterium; Magnetic Resonance Spectroscopy; Time Factors | 1974 |
Model reactions which establish a facile reduction of pyridoxal phosphate and analogs by 1,4-dihydropyridines.
Topics: Alanine; Aldehydes; Cations, Divalent; Chemical Phenomena; Chemistry; Deuterium; Hydrogen; Hydrogen-Ion Concentration; Hydroquinones; Imines; Kinetics; Magnetic Resonance Spectroscopy; Methanol; Models, Chemical; Niacinamide; Oxidation-Reduction; Pyridines; Pyridoxal; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet | 1973 |
Photochemistry of biological molecules. I. Photolysis of amino acids in the solid state.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Crystallization; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Glycine; Isoleucine; Radiation; Radiation Effects; Ultraviolet Rays; Valerates; Valine | 1967 |
Photochemistry of biological molecules. IV. Gaseous products from the photolysis of alanine peptides in the solid state.
Topics: Alanine; Chromatography, Gas; Deuterium; Electron Spin Resonance Spectroscopy; Peptides; Photolysis; Ultraviolet Rays | 1972 |
Nuclear magnetic resonance study on D-amino acid oxidase reaction.
Topics: Alanine; D-Amino-Acid Oxidase; Deuterium; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; Methods; Oxides; Pyruvates | 1970 |
Studies on the mechanism of action of D-amino acid oxidase. Evidence for removal of substrate -hydrogen as a proton.
Topics: Alanine; Chemical Phenomena; Chemistry; Chlorine; D-Amino-Acid Oxidase; Deuterium; Flavin-Adenine Dinucleotide; Hydrogen; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Models, Chemical; Nitrogen; Oxygen; Phenylhydrazines; Proline; Protons; Pyruvates; Quaternary Ammonium Compounds; Serine; Spectrophotometry; Stereoisomerism; Thiosemicarbazones; Tritium; Ultraviolet Rays | 1971 |
A novel approach for studies of the molecular conformations in flexible polypeptides.
Topics: Alanine; Calorimetry; Carbon Isotopes; Deuterium; Dimethyl Sulfoxide; Evaluation Studies as Topic; Kinetics; Magnetic Resonance Spectroscopy; Methods; Oligopeptides; Peptides; Phenylalanine; Proline; Protein Conformation; Structure-Activity Relationship; Thermodynamics | 1974 |
Selectivity in vitamin B-6 model reactions: selective alpha or beta deuteration of amino acids under transamination or racemization conditions.
Topics: Alanine; Amino Acids; Aminobutyrates; Binding Sites; Deuterium; Hydrogen-Ion Concentration; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Models, Biological; Molecular Conformation; Pyridoxal; Time Factors; Valine | 1974 |
Syntheses of further analogues of norphalloin. Gly1-, L-val1- and D-Abu2-norphalloin and (beta-trideutero)-Ala5- norphalloin.
Topics: Alanine; Aminobutyrates; Anhydrides; Animals; Chromatography, Thin Layer; Cyclization; Deuterium; Lethal Dose 50; Mice; Mycotoxins; Oligopeptides; Peptides, Cyclic; Phalloidine; Polarography; Temperature; Threonine; Valine | 1974 |
Multiple ion detection by accelerating voltage alternation in conjunction with voltage sweeping.
Topics: Alanine; Chromatography, Gas; Deuterium; Electricity; Glucose; Mass Spectrometry | 1974 |
Effect of alanine, leucine and fructose on lysyl-transfer ribonucleic acid ligase activity in a mutant of Escherichia coli K-12.
Topics: Alanine; Amino Acids; Amino Acyl-tRNA Synthetases; Carbohydrate Metabolism; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Culture Media; Deuterium; Escherichia coli; Fructose; Glucose; Leucine; Lysine; Mutation; Stereoisomerism; Stimulation, Chemical | 1973 |
Basis of transport discrimination of arginine from other basic amino acids in Salmonella typhimurium.
Topics: Alanine; Amino Acids; Arginine; Autoanalysis; Biological Transport; Carbon Radioisotopes; Chromatography, Ion Exchange; Deuterium; Glucose; Histidine; Homoserine; Hydroxyproline; Kinetics; Leucine; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Ornithine; Proline; Salmonella typhimurium; Structure-Activity Relationship; Tritium; Tryptophan | 1974 |
The preparation and subsequent identification of a dehydroalanyl peptide from alkali-treated oxidised glutathione.
Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Deuterium; Dicarboxylic Acids; Dipeptides; Electrophoresis; Glutamates; Glutathione; Glycine; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Oligopeptides; Oxidation-Reduction; Proteins; Protons; Sulfides | 1972 |
On the mechanism of action of streptococcal proteinase. 3. The effect of pH, organic solvents, and deuterium oxide on the proteinase-catalyzed hydrolysis of N-acylamino acid esters.
Topics: Acetates; Alanine; Amino Acids; Benzene Derivatives; Benzyl Compounds; Binding Sites; Binding, Competitive; Catalysis; Deuterium; Dimethyl Sulfoxide; Endopeptidases; Esters; Formates; Hydrogen-Ion Concentration; Kinetics; Lysine; Nitriles; Nitrobenzenes; Papain; Phosphates; Protease Inhibitors; Streptococcus; Tromethamine | 1973 |
The solution conformation of the ferrichromes. IV. pH dependence of the individual slow amide hydrogen-deuterium exchange in alumichrome.
Topics: Alanine; Aluminum; Amides; Binding Sites; Cold Temperature; Deuterium; Glycine; Half-Life; Hydrogen; Hydrogen-Ion Concentration; Hydroxamic Acids; Iron Chelating Agents; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Molecular Conformation; Ornithine; Peptides, Cyclic; Protons; Solutions; Thermodynamics; Tyrothricin | 1973 |
13C-nuclear magnetic resonance relaxation measurements of alpha-lecithin--peptide interaction in model membranes.
Topics: Alanine; Binding Sites; Carbon Isotopes; Deuterium; Dipeptides; Fourier Analysis; Glycine; Magnetic Resonance Spectroscopy; Membranes, Artificial; Molecular Conformation; Palmitic Acids; Phosphatidylcholines; Protein Conformation; Sodium; Structure-Activity Relationship; Temperature | 1974 |
Interactions of aromatic residues of proteins with nucleic acids. I. Proton magnetic resonance studies of the binding of tryptophan-containing peptides to poly(adenylic acid) and deoxyribonucleic acid.
Topics: Adenine Nucleotides; Alanine; Animals; Binding Sites; Cattle; Cold Temperature; Deuterium; DNA; Glycine; Hydrogen-Ion Concentration; Indoles; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Methyl Ethers; Nucleic Acid Conformation; Oligopeptides; Osmolar Concentration; Polynucleotides; Protons; Serotonin; Sodium Chloride; Structure-Activity Relationship; Thymus Gland; Tryptamines; Tryptophan | 1974 |
Structure and mode of action of glycoproteins from an antarctic fish.
Topics: Acylation; Alanine; Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Blood Physiological Phenomena; Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Disaccharides; Fishes; Freezing; Galactose; Galactosidases; Glycols; Glycoproteins; Magnetic Resonance Spectroscopy; Models, Structural; Oxidation-Reduction; Plants; Threonine | 1972 |
The use of p-nitrophenyl N-tert-butyloxycarbonyl-L-alaninate as substrate for elastase.
Topics: Alanine; Animals; Butanols; Cell Wall; Deuterium; Formates; Hydrogen-Ion Concentration; Kinetics; Methods; Micrococcus; Nitrobenzenes; Pancreas; Pancreatic Elastase; Spectrophotometry; Swine; Ultraviolet Rays | 1972 |
Cystathionine -synthase. Studies of hydrogen exchange reactions.
Topics: Alanine; Aminobutyrates; Catalysis; Chemical Phenomena; Chemistry; Cystathionine; Cysteine; Deuterium; Homoserine; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Salmonella; Serine; Succinates; Tritium | 1972 |
Phonon dispersion curves and normal coordinate analysis of -poly-L-alanine.
Topics: Alanine; Deuterium; Peptides; Spectrum Analysis; Vibration | 1971 |
Experimental and calculated conformational characteristics of the cyclic decapeptide antamanide.
Topics: 1-Propanol; Alanine; Chemical Phenomena; Chemistry, Physical; Chloroform; Circular Dichroism; Deuterium; Dioxins; Ethanol; Fluorine; Magnetic Resonance Spectroscopy; Mathematics; Methanol; Models, Chemical; Models, Structural; Peptides; Peptides, Cyclic; Phenylalanine; Proline; Protein Conformation; Ultraviolet Rays; Valine | 1971 |
Mass spectral analysis of C 3 and C 4 aliphatic amino acid derivatives.
Topics: Alanine; Alkylation; Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Aminopropionitrile; Chemical Phenomena; Chemistry; Deuterium; Esters; Fluoroacetates; Glycine; Isomerism; Mass Spectrometry; Methods; Sarcosine; Spectrum Analysis | 1971 |
Dissociation constants of lanthionine and its structure in aqueous solution.
Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry; Chlorine; Computers; Cysteine; Deuterium; Dicarboxylic Acids; Hydrogen-Ion Concentration; Infrared Rays; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Nitrates; Optical Rotatory Dispersion; Potentiometry; Sodium; Spectrophotometry; Stereoisomerism; Sulfides; Temperature; Thermodynamics; Tosyl Compounds | 1971 |
Use of chemical ionization mass spectrometry in analysis of amino acid phenylthiohydantoin derivatives formed during Edman degradation of proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Cetacea; Chromatography, Gas; Deuterium; Glutamine; Glycine; Hydantoins; Leucine; Mass Spectrometry; Methods; Myoglobin; Sulfides; Tryptophan; Valine | 1971 |
The biosynthesis of isotope hybrid proteins for high resolution nuclear magnetic resonance studies by incorporation of [1H]amino acids into fully deuterated algae.
Topics: Alanine; Amino Acids; Deuterium; Eukaryota; Hydrogen; Leucine; Magnetic Resonance Spectroscopy; Methionine; Phenylalanine; Protein Biosynthesis; Tyrosine | 1970 |
Catalytic reactions involving azomethines. XII. Transamination of 1-methyl-3-hydroxy-4-formylpyridinium chloride.
Topics: Alanine; Aldehydes; Azo Compounds; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Computers; Deuterium; Formates; Hydrogen-Ion Concentration; Imines; Kinetics; Methylation; Osmolar Concentration; Pyridinium Compounds; Spectrophotometry; Ultraviolet Rays | 1970 |
Gas-liquid chromatography and mass spectrometry of deuterium-containing amino acids as their trimethylsilyl derivatives.
Topics: Alanine; Amino Acids; Asparagine; Chromatography, Gas; Deuterium; Glycine; Leucine; Methionine; Proline; Silicon; Spectrum Analysis; Tyrosine; Valine | 1970 |
Infrared absorption spectrum of water adsorbed on alpha-helical synthetic polypeptides.
Topics: Alanine; Deuterium; Glutamates; Infrared Rays; Peptides; Spectrum Analysis; Water | 1970 |
A comparison of properties of the alpha-lytic protease of Sorangium sp. and porcine elastase.
Topics: Alanine; Amino Acids; Animals; Deuterium; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Ketones; Kinetics; Leucine; Myxomycetes; Optical Rotatory Dispersion; Pancreatic Elastase; Peptide Hydrolases; Serine; Swine | 1970 |
Effect of conformation on isotopic exchange in synthetic polypeptides.
Topics: Alanine; Amides; Chemical Phenomena; Chemistry; Deuterium; Glutamates; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Mathematics; Osmolar Concentration; Peptides; Temperature; Thermodynamics; Tritium | 1970 |
Isolation, purification, and characterization of anticapsin.
Topics: Alanine; Amino Acids; Chromatography, Paper; Culture Media; Deuterium; Ethers, Cyclic; Fermentation; Filtration; Indicators and Reagents; Magnetic Resonance Spectroscopy; Solvents; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Streptomyces | 1970 |
Nuclear magnetic resonance study of cyanoferrimyoglobin; identification of pseudocontact shifts.
Topics: Alanine; Ammonia; Animals; Cetacea; Chemical Phenomena; Chemistry; Cyanides; Deuterium; Dolphins; Electrons; Histidine; Horses; Magnetic Resonance Spectroscopy; Methylation; Myoglobin; Protons; Serine; Temperature | 1970 |
The conformation of poly-beta-alanine in aqueous solution from proton magnetic resonance and deuterium exchange studies.
Topics: Alanine; Deuterium; Magnetic Resonance Spectroscopy; Molecular Weight; Peptides; Solutions | 1971 |
The enzymatic carboxylation of propionyl coenzyme A. Studies involving deuterated and tritiated substrates.
Topics: Alanine; Aluminum; Chemical Phenomena; Chemistry; Chromatography, Gas; Coenzyme A; Deuterium; Ligases; Lithium; Magnetic Resonance Spectroscopy; Malonates; Propionates; Protons; Tritium | 1968 |
Stereochemistry of transamination catalyzed by pyridoxamine--pyruvate transaminase.
Topics: Alanine; Amines; Chemical Phenomena; Chemistry; Crystallization; Deuterium; Kinetics; Magnetic Resonance Spectroscopy; Protons; Pyridines; Pyruvates; Spectrophotometry; Spectrum Analysis; Stereoisomerism; Transaminases | 1968 |
Stereospecific catalytic labelling of amino-acids and mandelic acid with isotopic hydrogen.
Topics: Alanine; Catalysis; Deuterium; Mandelic Acids; Phenylalanine | 1966 |
Alanine aminotransferase. II. The basis for substrate specificity.
Topics: Alanine; Alanine Transaminase; Amino Acids; Aminobutyrates; Animals; Chemical Phenomena; Chemistry; Deuterium; Formates; Glutamates; In Vitro Techniques; Kinetics; Leucine; Myocardium; Ornithine; Swine | 1967 |
Hydrogen-deuterium exchange in gamma-irradiated polycrystalline DL-alanine: a spin-trapping and e.s.r. study.
Topics: Alanine; Deuterium; Electron Spin Resonance Spectroscopy; Free Radicals; Gamma Rays; Hydrogen | 1981 |
Effects of epinephrine infusion on leucine and alanine kinetics in humans.
Topics: Adolescent; Adult; Alanine; Blood Glucose; Deuterium; Epinephrine; Gas Chromatography-Mass Spectrometry; Glucagon; Humans; Insulin; Kinetics; Leucine; Nitrogen Isotopes | 1984 |
Alanine kinetics in humans: influence of different isotopic tracers.
Topics: Adult; Alanine; Body Height; Body Weight; Carbon Isotopes; Deuterium; Diet; Humans; Kinetics; Male; Nitrogen Isotopes | 1984 |
Use of isotope effects and pH studies to determine the chemical mechanism of Bacillus subtilis L-alanine dehydrogenase.
Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Bacillus subtilis; Chemical Phenomena; Chemistry, Physical; Deuterium; Hydrogen-Ion Concentration; Mathematics; NAD; Serine | 1981 |
Equilibrium and kinetic study of interaction of amino acid inhibitors with tryptophanase: mechanism of quinonoid formation.
Topics: Alanine; Deuterium; Escherichia coli; Ethionine; Hydrogen-Ion Concentration; Kinetics; Lyases; Protein Binding; Pyridoxal Phosphate; Quinones; Spectrophotometry; Tryptophanase | 1981 |
Different modes of action of inhibitors of bacterial D-amino acid transaminase. A target enzyme for the design of new antibacterial agents.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Bacillus; Binding Sites; Cyclohexanecarboxylic Acids; Cyclohexylamines; Cycloserine; D-Alanine Transaminase; Deuterium; Ketoglutaric Acids; Kinetics; Structure-Activity Relationship; Transaminases | 1981 |
Mechanism-based inactivation of serine transhydroxymethylases by D-fluoroalanine and related amino acids.
Topics: Alanine; Animals; Deuterium; Glycine Hydroxymethyltransferase; Kinetics; Liver; Rabbits; Sheep; Spectrophotometry; Structure-Activity Relationship; Transferases | 1981 |
Deuterium nuclear magnetic resonance of specifically labeled native collagen. Investigation of protein molecular dynamics using the quadrupolar echo technique.
Topics: Alanine; Animals; Bone and Bones; Chickens; Collagen; Deuterium; Leucine; Magnetic Resonance Spectroscopy; Mathematics; Models, Biological; Protein Conformation | 1980 |
2H NMR study of molecular motion in collagen fibrils.
Topics: Alanine; Animals; Cartilage; Cells, Cultured; Chickens; Collagen; Deuterium; Magnetic Resonance Spectroscopy; Motion | 1980 |
Effects of deuterium labeling on azido amino acid mutagenicity in Salmonella typhimurium.
Topics: Alanine; Azides; Biotransformation; Deuterium; Isotope Labeling; Mutagenicity Tests; Mutagens; Salmonella typhi | 1994 |
Improved sensitivity of HSQC spectra of exchanging protons at short interscan delays using a new fast HSQC (FHSQC) detection scheme that avoids water saturation.
Topics: Alanine; Artifacts; Deuterium; Diffusion; Hydrogen; Image Enhancement; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Nitrogen Isotopes; Protons; Water | 1995 |
Peptide chiral purity determination: hydrolysis in deuterated acid, derivatization with Marfey's reagent and analysis using high-performance liquid chromatography-electrospray ionization-mass spectrometry.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Chromatography, High Pressure Liquid; Deuterium; Dinitrobenzenes; Hydrolysis; Indicators and Reagents; Mass Spectrometry; Molecular Sequence Data; Peptides; Protein Conformation | 1995 |
1H-2H exchange in the perfused rat liver metabolizing [3-13C]alanine and 2H2O as detected by multinuclear NMR spectroscopy.
Topics: Alanine; Animals; Aspartic Acid; Carbon Isotopes; Deuterium; Deuterium Oxide; Glutamic Acid; Hydrogen; Liver; Magnetic Resonance Spectroscopy; Male; Perfusion; Rats; Rats, Sprague-Dawley | 1994 |
Intrinsic primary, secondary, and solvent kinetic isotope effects on the reductive half-reaction of D-amino acid oxidase: evidence against a concerted mechanism.
Topics: Alanine; Catalysis; D-Amino-Acid Oxidase; Deuterium; Glycine; Kinetics; Serine; Solvents; Structure-Activity Relationship; Tritium | 1994 |
Generation of C3- and C2-deuterated L-lactic acid by human erythrocytes exposed to D-[1-13C]glucose, D-[2-13C]glucose and D-[6-13C]glucose in the presence of D2O.
Topics: Alanine; Alanine Transaminase; Carbon Isotopes; Deuterium; Erythrocytes; Glucose; Glycolysis; Humans; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvates; Pyruvic Acid | 1994 |
Measurement of plasma protein synthesis rate in infant pig: an investigation of alternative tracer approaches.
Topics: Alanine; Animals; Animals, Newborn; Apolipoprotein B-100; Apolipoproteins B; Blood Proteins; Carbon Isotopes; Deuterium; Female; Fibrinogen; Leucine; Liver; Lysine; Male; Serum Albumin; Swine | 1994 |
Kinetic mechanism of D-amino acid oxidases from Rhodotorula gracilis and Trigonopsis variabilis.
Topics: Alanine; Animals; D-Amino-Acid Oxidase; Deuterium; Kidney; Kinetics; Mathematics; Mitosporic Fungi; Models, Biological; Radioisotope Dilution Technique; Rhodotorula; Spectrophotometry; Substrate Specificity; Swine; Valine | 1993 |
Assessment of proinsulin's effects on intermediary metabolism using the forearm technique in normal man.
Topics: Adult; Alanine; Blood Glucose; Deuterium; Forearm; Glucose; Glucose Clamp Technique; Glycerol; Humans; Insulin; Lactates; Liver; Male; Proinsulin; Pyruvates; Radioisotope Dilution Technique; Reference Values | 1993 |
Inactivation of gamma-aminobutyric acid aminotransferase by L-3-chloroalanine hydroxamate.
Topics: 4-Aminobutyrate Transaminase; Alanine; Animals; Buffers; Cyclohexanecarboxylic Acids; Cycloserine; Deuterium; Prodrugs; Pyridoxal Phosphate; Swine; Time Factors | 1995 |
1H-NMR and 13C-NMR investigation of complexes of Mn2+ with ocytocin analogues in (2H6)dimethylsulfoxide.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Carbon Isotopes; Cysteine; Deuterium; Dimethyl Sulfoxide; Glutamine; Hydrogen; Magnetic Resonance Spectroscopy; Manganese; Models, Molecular; Molecular Sequence Data; Oxytocin; Proline; Protein Binding; Protein Conformation; Sarcosine; Sulfhydryl Compounds; Thermodynamics; Threonine | 1996 |
A 2H NMR spin-lattice relaxation study of -NH+3 group dynamics in polycrystalline L-alanine.
Topics: Alanine; Algorithms; Ammonia; Crystallization; Deuterium; Electron Spin Resonance Spectroscopy; Magnetic Resonance Spectroscopy; Temperature | 1996 |
[Liver urea and glucose production in patients with alcohol-induced cirrhosis].
Topics: Adult; Alanine; Amino Acids; Deuterium; Epinephrine; Glucagon; Glucose; Humans; Insulin; Liver; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Nitrogen Isotopes; Norepinephrine; Urea | 1997 |
Glucose metabolism during exercise in man: the role of insulin and glucagon in the regulation of hepatic glucose production and gluconeogenesis.
Topics: Adult; Alanine; Blood Glucose; Carbon Isotopes; Deuterium; Exercise; Fasting; Glucagon; Gluconeogenesis; Glucose; Glycerol; Humans; Insulin; Insulin Secretion; Lactic Acid; Liver; Male; Pancreatic Hormones; Somatostatin | 1997 |
Limited proteolysis and X-ray crystallography reveal the origin of substrate specificity and of the rate-limiting product release during oxidation of D-amino acids catalyzed by mammalian D-amino acid oxidase.
Topics: Alanine; Amino Acids; Animals; Benzoates; Binding Sites; Catalysis; Crystallography, X-Ray; D-Amino-Acid Oxidase; Deuterium; Flavin-Adenine Dinucleotide; Hydrolysis; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Substrate Specificity; Swine; Trypsin | 1997 |
Glucose turnover and gluconeogenesis during pregnancy in women with and without insulin-dependent diabetes mellitus.
Topics: Alanine; Carbon Isotopes; Deuterium; Diabetes Mellitus, Type 1; Estradiol; Fasting; Female; Glucagon; Gluconeogenesis; Glucose; Humans; Hydrocortisone; Insulin; Liver; Placental Lactogen; Pregnancy; Pregnancy in Diabetics; Progesterone; Prolactin; Prospective Studies | 1997 |
Glucose production and gluconeogenesis in adults with uncomplicated falciparum malaria.
Topics: Adult; Alanine; Deuterium; Epinephrine; Glucagon; Gluconeogenesis; Glucose; Glycerol; Glycogen; Humans; Hydrocortisone; Insulin; Lactates; Malaria, Falciparum; Male; Norepinephrine; Radioisotope Dilution Technique; Reference Values; Vietnam | 1997 |
Glucose homeostasis in children with falciparum malaria: precursor supply limits gluconeogenesis and glucose production.
Topics: Alanine; Blood Glucose; Child; Child, Preschool; Cytokines; Deuterium; Female; Gluconeogenesis; Glucose; Glycerol; Homeostasis; Humans; Hydrocortisone; Insulin; Kenya; Kinetics; Lactic Acid; Malaria, Falciparum; Male | 1997 |
Design of solenoidal microcoils for high-resolution 13C NMR spectroscopy.
Topics: Alanine; Carbon Isotopes; Deuterium; Magnetic Resonance Spectroscopy; Stereoisomerism; Sucrose | 1998 |
Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate.
Topics: Alanine; Binding Sites; Circular Dichroism; Cysteine; Cysteine Synthase; Deuterium; Enzyme Activation; Enzyme Stability; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Insertional; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1998 |
The behavior of substrate analogues and secondary deuterium isotope effects in the phenylalanine ammonia-lyase reaction.
Topics: Alanine; Cresols; Deuterium; Enzyme Activation; Glycine; Hydrocarbons, Cyclic; Isotope Labeling; Kinetics; Phenylalanine; Phenylalanine Ammonia-Lyase; Pyridines; Substrate Specificity | 1998 |
Effects of a high-fat diet and voluntary wheel running on gluconeogenesis and lipolysis in rats.
Topics: Adipose Tissue; Alanine; Animals; Blood Glucose; Citrate (si)-Synthase; Deuterium; Dietary Fats; Energy Intake; Gluconeogenesis; Glucose; Glycerol; Lipolysis; Male; Muscle, Skeletal; Organ Size; Physical Conditioning, Animal; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Rats, Wistar; Tritium; Weight Gain | 1999 |
Raman markers of nonaromatic side chains in an alpha-helix assembly: Ala, Asp, Glu, Gly, Ile, Leu, Lys, Ser, and Val residues of phage fd subunits.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Deuterium; DNA, Single-Stranded; Glutamic Acid; Glycine; Inovirus; Isoleucine; Lysine; Molecular Sequence Data; Protein Structure, Secondary; Serine; Spectrum Analysis, Raman; Valine; Viral Proteins; Virus Assembly | 1999 |
(S)-Mandelate dehydrogenase from Pseudomonas putida: mutations of the catalytic base histidine-274 and chemical rescue of activity.
Topics: Alanine; Alcohol Oxidoreductases; Asparagine; Binding Sites; Catalysis; Deuterium; Enzyme Inhibitors; Flavin Mononucleotide; Glycine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Mandelic Acids; Mutagenesis, Site-Directed; Pseudomonas putida; Recombinant Proteins; Substrate Specificity; Sulfites | 1999 |
Tritium secondary kinetic isotope effect on phenylalanine ammonia-lyase-catalyzed reaction.
Topics: Alanine; Catalytic Domain; Deuterium; Kinetics; Models, Chemical; Phenylalanine Ammonia-Lyase; Rhodotorula; Substrate Specificity; Tritium | 1999 |
Steric interactions of valines 1, 5, and 7 in [valine 5, D-alanine 8] gramicidin A channels.
Topics: Acylation; Alanine; Deuterium; Dimyristoylphosphatidylcholine; Ethanolamine; Gramicidin; Hydrogen Bonding; Ion Channels; Kinetics; Lipid Bilayers; Magnetic Resonance Spectroscopy; Methylation; Models, Molecular; Palmitic Acid; Protein Conformation; Temperature; Valine; Water | 1999 |
Catalytic mechanism of the tryptophan synthase alpha(2)beta(2) complex. Effects of pH, isotopic substitution, and allosteric ligands.
Topics: Alanine; Allosteric Regulation; Catalytic Domain; Deuterium; Glycine; Hydrogen-Ion Concentration; Indoles; Ligands; Models, Chemical; Oxindoles; Pyridoxal Phosphate; Salmonella typhimurium; Serine; Tryptophan Synthase | 1999 |
Efficient deuterium-carbon REDOR NMR spectroscopy.
Topics: Alanine; Carbon Isotopes; Deuterium; Magnetic Resonance Spectroscopy; Malonates; Molecular Conformation | 2000 |
Protection of radical intermediates at the active site of adenosylcobalamin-dependent methylmalonyl-CoA mutase.
Topics: Aerobiosis; Alanine; Binding Sites; Cobamides; Crystallization; Crystallography, X-Ray; Deuterium; Free Radicals; Glutamine; Histidine; Kinetics; Methylmalonyl-CoA Mutase; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Propionibacterium; Spectrophotometry, Ultraviolet; Spectrum Analysis; Tritium | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Identification of active site residues in E. coli ketopantoate reductase by mutagenesis and chemical rescue.
Topics: Acetic Acid; Alanine; Alcohol Oxidoreductases; Alkylation; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Cysteine; Deuterium; Escherichia coli; Formates; Gene Expression Regulation, Bacterial; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Pantothenic Acid; Recombinant Proteins; Sequence Alignment; Substrate Specificity | 2000 |
Rapid kinetic and isotopic studies on dialkylglycine decarboxylase.
Topics: Alanine; Aminoisobutyric Acids; Carbon Isotopes; Carboxy-Lyases; Decarboxylation; Deuterium; Enzyme Activation; Isoenzymes; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Protons; Pyridoxal Phosphate; Pyruvic Acid; Transaminases | 2001 |
Oxidations of p-alkoxyacylanilides catalyzed by human cytochrome P450 1A2: structure-activity relationships and simulation of rate constants of individual steps in catalysis.
Topics: Alanine; Alkylation; Amino Acid Substitution; Aspartic Acid; Catalysis; Cytochrome P-450 CYP1A2; Deuterium; Enzyme Activation; Humans; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenacetin; Protein Binding; Structure-Activity Relationship; Substrate Specificity | 2001 |
Investigation of allosteric linkages in the regulation of tryptophan synthase: the roles of salt bridges and monovalent cations probed by site-directed mutation, optical spectroscopy, and kinetics.
Topics: Alanine; Allosteric Regulation; Asparagine; Aspartic Acid; Cations, Monovalent; Deuterium; Dimerization; Enzyme Activation; Kinetics; Lysine; Multienzyme Complexes; Mutagenesis, Site-Directed; Potassium; Quaternary Ammonium Compounds; Salmonella typhimurium; Salts; Sodium; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Threonine; Titrimetry; Tryptophan Synthase | 2001 |
Acid-base catalysis by UDP-galactose 4-epimerase: correlations of kinetically measured acid dissociation constants with thermodynamic values for tyrosine 149.
Topics: Alanine; Catalysis; Deuterium; Electron Transport; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protons; Serine; Spectrometry, Fluorescence; Temperature; Thermodynamics; Tyrosine; UDPglucose 4-Epimerase | 2001 |
Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity.
Topics: Alanine; Allosteric Regulation; Aniline Compounds; Aspartic Acid; Benzimidazoles; beta-Alanine; Catalysis; Deuterium; Enzyme Activation; Hydroxylamines; Indoles; Kinetics; Multienzyme Complexes; Mutagenesis, Site-Directed; Pyruvic Acid; Salmonella typhimurium; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Titrimetry; Tryptophan Synthase | 2001 |
Membrane interactions of mutated forms of the influenza fusion peptide.
Topics: Alanine; Amino Acid Sequence; Deuterium; Glutamic Acid; Glycine; Hemagglutinin Glycoproteins, Influenza Virus; Kinetics; Lipid Bilayers; Membrane Fusion; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phosphorus Isotopes; Protein Conformation; Protein Structure, Secondary; Serine; Spectroscopy, Fourier Transform Infrared; Valine; Viral Fusion Proteins | 2001 |
pH and kinetic isotope effects in d-amino acid oxidase catalysis.
Topics: Alanine; Asparagine; Catalysis; D-Amino-Acid Oxidase; Deuterium; Hydrogen-Ion Concentration; Kinetics; Protons; Rhodotorula; Solvents; Spectrophotometry | 2001 |
Kinetic and mechanistic studies of penicillin-binding protein 2x from Streptococcus pneumoniae.
Topics: Acylation; Alanine; Carrier Proteins; Catalysis; Cloning, Molecular; Deuterium; Enzyme Inhibitors; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Multienzyme Complexes; Penicillin G; Penicillin-Binding Proteins; Peptide Fragments; Protons; Recombinant Proteins; Solvents; Streptococcus pneumoniae; Substrate Specificity; Temperature; Thermodynamics; Thioglycolates | 2001 |
A ruthenium(II) tris(bipyridyl) amino acid: synthesis and direct incorporation into an alpha-helical peptide by solid-phase synthesis.
Topics: 2,2'-Dipyridyl; Alanine; Algorithms; Amino Acid Sequence; Amino Acids; Catalysis; Circular Dichroism; Deuterium; Histidine; Hydrogen; Lysine; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Organometallic Compounds; Peptides; Ruthenium; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Temperature; Time Factors | 2002 |
A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility.
Topics: Alanine; Amino Acid Sequence; Animals; Aprotinin; Cattle; Deuterium; Disulfides; Enzyme Stability; Glycine; Isomerism; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Point Mutation; Protein Conformation; Protein Folding; Protons; Thermodynamics; Trypsin Inhibitors | 2002 |
Amino acid kinetics during the anhepatic phase of liver transplantation.
Topics: Alanine; Amino Acids; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Deuterium; Electrolytes; Fatty Acids, Nonesterified; Gluconeogenesis; Glutamine; Glycerol; Hematocrit; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Leucine; Liver; Liver Transplantation; Metabolic Clearance Rate; Middle Aged; Nitrogen; Oxygen; Pyruvic Acid | 2002 |
Functional and structural changes due to a serine to alanine mutation in the active-site flap of enolase.
Topics: Alanine; Amino Acid Substitution; Catalytic Domain; Crystallography, X-Ray; Deuterium; Enzyme Activation; Escherichia coli; Kinetics; Metals; Models, Molecular; Mutagenesis, Site-Directed; Phosphopyruvate Hydratase; Protein Conformation; Protein Folding; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Static Electricity; Thermodynamics | 2002 |
Key motif to gain selectivity at the neuropeptide Y5-receptor: structure and dynamics of micelle-bound [Ala31, Pro32]-NPY.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Circular Dichroism; Crystallography, X-Ray; Deuterium; Micelles; Molecular Sequence Data; Mutagenesis, Site-Directed; Neuropeptide Y; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphorylcholine; Proline; Protein Conformation; Protein Structure, Secondary; Protons; Rats; Receptors, Neuropeptide Y; Spin Labels; Thermodynamics | 2002 |
D/H amide isotope effect in model alpha-helical peptides.
Topics: Alanine; Amides; Amino Acid Sequence; Circular Dichroism; Deuterium; DNA-Binding Proteins; Guanidine; Kinetics; Molecular Sequence Data; Peptides; Protein Kinases; Protein Structure, Secondary; Saccharomyces cerevisiae Proteins | 2002 |
Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction.
Topics: Alanine; Aspartic Acid; Binding Sites; Catalysis; Circular Dichroism; Cysteine Synthase; Deuterium; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Pyridines; Pyridoxal Phosphate; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity | 2003 |
REDOR with a relative full-echo reference.
Topics: Alanine; Anti-Bacterial Agents; Binding Sites; Cell Membrane; Computer Simulation; Deuterium; Isotope Labeling; Membrane Proteins; Models, Biological; Models, Chemical; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Spin Labels; Staphylococcus aureus; Vancomycin | 2003 |
2H[19F] REDOR for distance measurements in biological solids using a double resonance spectrometer.
Topics: Alanine; Crystallography; Deuterium; Feasibility Studies; Fluorine Radioisotopes; H(+)-K(+)-Exchanging ATPase; Isotope Labeling; Magnetic Resonance Spectroscopy; Protein Conformation; Proton Pump Inhibitors; Pyridines; Spin Labels; Stomach | 2004 |
Isotopic discrimination between D-[1-(13)C]fructose and D-[2-(13)C]fructose in rat liver cells.
Topics: Alanine; Animals; Carbon Isotopes; Cell Separation; Deuterium; Diabetes Mellitus, Experimental; Fructose; Glucose; Hepatocytes; Lactic Acid; Rats; Rats, Inbred Strains; Rats, Wistar | 2004 |
Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacterial Proteins; Bacteriocins; Boranes; Deuterium; Drug Synergism; Lactococcus lactis; Molecular Sequence Data; Nickel; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peptide Fragments; Protein Conformation; Solutions; Structure-Activity Relationship; Sulfides; Sulfur; Thermodynamics | 2004 |
The stereospecificity and catalytic efficiency of the tryptophan synthase-catalysed exchange of the alpha-protons of amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Catalysis; Deuterium; Glycine Hydroxymethyltransferase; Hydrogen; Kinetics; Norleucine; Nuclear Magnetic Resonance, Biomolecular; Predictive Value of Tests; Protons; Serine; Stereoisomerism; Substrate Specificity; Tryptophan; Tryptophan Synthase; Valine | 2004 |
Studies of the enzymic mechanism of Candida tenuis xylose reductase (AKR 2B5): X-ray structure and catalytic reaction profile for the H113A mutant.
Topics: Alanine; Aldehyde Reductase; Amino Acid Substitution; Binding Sites; Candida; Catalysis; Crystallography, X-Ray; Deuterium; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; NAD; Quantitative Structure-Activity Relationship | 2004 |
Alanine racemase free energy profiles from global analyses of progress curves.
Topics: Alanine; Alanine Racemase; Deuterium; Geobacillus stearothermophilus; Hydrogen-Ion Concentration; Kinetics; Models, Theoretical; Molecular Structure; Oxidation-Reduction; Quinones; Solvents; Stereoisomerism | 2004 |
Tilt and rotational pitch angle of membrane-inserted polypeptides from combined 15N and 2H solid-state NMR spectroscopy.
Topics: Alanine; Cell Membrane; Deuterium; Lipid Bilayers; Magnetic Resonance Spectroscopy; Peptides; Phospholipids | 2004 |
Supplementation with aromatic amino acids improves leucine kinetics but not aromatic amino acid kinetics in infants with infection, severe malnutrition, and edema.
Topics: Alanine; Amino Acids, Aromatic; Anthropometry; Body Water; Deuterium; Edema; Enteral Nutrition; Humans; Infant; Infections; Intubation, Gastrointestinal; Kinetics; Leucine; Phenylalanine; Protein-Energy Malnutrition; Proteins; Tryptophan; Tyrosine | 2004 |
Investigations of polypeptide rotational diffusion in aligned membranes by 2H and 15N solid-state NMR spectroscopy.
Topics: Alanine; Deuterium; Diffusion; Leucine; Lipid Bilayers; Membrane Proteins; Membranes, Artificial; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylcholines; Protein Structure, Secondary | 2004 |
Dynamic changes in protein-protein interaction and protein phosphorylation probed with amine-reactive isotope tag.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Blotting, Western; Cell Cycle Proteins; Checkpoint Kinase 2; Chromatography, Ion Exchange; Deuterium; DNA Damage; Electrophoresis, Polyacrylamide Gel; Hydrogen; Isotope Labeling; Methyl Methanesulfonate; Mutagenesis, Site-Directed; Mutagens; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2005 |
Accelerated hepatic glycerol synthesis in rainbow smelt (Osmerus mordax) is fuelled directly by glucose and alanine: a 1H and 13C nuclear magnetic resonance study.
Topics: Alanine; Animals; Carbon Isotopes; Deuterium; Glucose; Glycerol; Liver; Magnetic Resonance Spectroscopy; Osmeriformes; Temperature | 2006 |
Infrared line shape of an alpha-carbon deuterium-labeled amino acid.
Topics: Alanine; Algorithms; Amino Acids; Carbon; Deuterium; Isotope Labeling; Models, Molecular; Spectrophotometry, Infrared | 2006 |
Probing the molecular dynamics of the ABC multidrug transporter LmrA by deuterium solid-state nuclear magnetic resonance.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Deuterium; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Nuclear Magnetic Resonance, Biomolecular; Phosphorus Isotopes | 2007 |
Tunable-alignment chiral system based on gelatin for NMR spectroscopy.
Topics: Alanine; Anisotropy; Deuterium; Gelatin; Magnetic Resonance Spectroscopy; Molecular Conformation; Stereoisomerism | 2007 |
Structural isotopic effects in the smallest chiral amino acid: observation of a structural phase transition in fully deuterated alanine.
Topics: Alanine; Deuterium; Molecular Structure; Neutron Diffraction; Phase Transition; Spectrum Analysis, Raman | 2007 |
Rate-limiting steps and role of active site Lys443 in the mechanism of carbapenam synthetase.
Topics: Alanine; Binding Sites; Carbon-Nitrogen Ligases; Catalysis; Deuterium; Enzyme Activation; Escherichia coli Proteins; Genetic Variation; Hydrogen-Ion Concentration; Kinetics; Lysine; Solvents; Substrate Specificity; Viscosity | 2007 |
Coherence transfer between spy nuclei and nitrogen-14 in solids.
Topics: Alanine; Carbon Isotopes; Deuterium; Glycine; Isotopes; Magnetic Resonance Spectroscopy; Nitrogen; Nitrogen Isotopes; Phosphorus Isotopes; Spectrum Analysis | 2008 |
Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Carrier Proteins; Deuterium; DNA-Binding Proteins; Dose-Response Relationship, Drug; Glutathione Transferase; Glycine; Guanidine; Humans; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ligands; Lysine; Models, Molecular; Mutation; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; Substrate Specificity; Temperature; Thermodynamics; Ubiquitin; Ubiquitination | 2008 |
Elevated gluconeogenesis and lack of suppression by insulin contribute to cystic fibrosis-related diabetes.
Topics: Adult; Alanine; Carbon Isotopes; Cystic Fibrosis; Deuterium; Diabetes Mellitus, Type 2; Female; Gluconeogenesis; Glucose Intolerance; Glucose Tolerance Test; Glutamine; Humans; Hydrocortisone; Insulin; Male; Proteins; Radionuclide Imaging | 2008 |
An efficient protocol for the complete incorporation of methyl-protonated alanine in perdeuterated protein.
Topics: Alanine; Carbon Isotopes; Culture Media; Deuterium; Escherichia coli; Hemiterpenes; Humans; Isoleucine; Isotope Labeling; Keto Acids; Malate Synthase; Metabolic Networks and Pathways; Nuclear Magnetic Resonance, Biomolecular; Proteins; Succinic Acid; Ubiquitin | 2009 |
Qualitative analysis of collective mode frequency shifts in L-alanine using terahertz spectroscopy.
Topics: Absorption; Alanine; Deuterium; Spectrum Analysis; Temperature | 2009 |
Solid-state NMR ensemble dynamics as a mediator between experiment and simulation.
Topics: Alanine; Deuterium; Dimyristoylphosphatidylcholine; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Peptides; Protein Structure, Secondary; Rotation | 2011 |
Dynamic nuclear polarization-enhanced ¹H-¹³C double resonance NMR in static samples below 20 K.
Topics: Alanine; Algorithms; Amyloid beta-Peptides; Calibration; Carbon Isotopes; Cold Temperature; Deuterium; Magnetic Resonance Spectroscopy; Microwaves; Peptide Fragments; Radio Waves | 2012 |
Stereoselective synthesis of deuterium-labeled (2S)-cyclohexenyl alanines, biosynthetic intermediates of cinnabaramide.
Topics: Alanine; Alkynes; Aspartic Acid; Cyclohexenes; Deuterium; Lactones; Molecular Structure; Stereoisomerism | 2012 |
2H-13C HETCOR MAS NMR for indirect detection of 2H quadrupole patterns and spin-lattice relaxation rates.
Topics: Alanine; Algorithms; Deuterium; Electromagnetic Fields; Isotope Labeling; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Proline | 2013 |
"On-the-fly" kinetics of enzymatic racemization using deuterium NMR in DNA-based chiral oriented media.
Topics: Alanine; Alanine Racemase; Deuterium; DNA; Geobacillus stearothermophilus; Kinetics; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism | 2013 |
Solid-State NMR Study of Paramagnetic Bis(alaninato-κ(2)N,O)copper(II) and Bis(1-amino(cyclo)alkane-1-carboxylato-κ(2)N,O)copper(II) Complexes: Reflection of Stereoisomerism and Molecular Mobility in (13)C and (2)H Fast Magic Angle Spinning Spectra.
Topics: Alanine; Amino Acids, Diamino; Carboxylic Acids; Coordination Complexes; Copper; Crystallography, X-Ray; Deuterium; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Organometallic Compounds; Quantum Theory; Stereoisomerism | 2015 |
Catalytic Stereoinversion of L-Alanine to Deuterated D-Alanine.
Topics: Alanine; Catalysis; Chloroform; Deuterium; Deuterium Oxide; Magnetic Resonance Spectroscopy; Stereoisomerism; Thermodynamics | 2015 |
Filterable Agents for Hyperpolarization of Water, Metabolites, and Proteins.
Topics: Acetates; Acrylic Resins; Alanine; Carbon Isotopes; Deuterium; Free Radicals; Freezing; Magnetic Resonance Spectroscopy; Metabolomics; Nitrogen Oxides; Pharmaceutical Preparations; Proteins; Protons; Pyruvates; Solubility; Water | 2016 |
Influence of glutamic acid residues and pH on the properties of transmembrane helices.
Topics: Alanine; Amino Acid Sequence; Animals; Deuterium; Glutamic Acid; Hydrogen-Ion Concentration; Lipid Bilayers; Membrane Proteins; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary | 2017 |
Profiling ephedrine prepared from N-methylalanine via the Akabori-Momotani reaction.
Topics: Alanine; Benzaldehydes; Carbon Isotopes; Central Nervous System Stimulants; Chemistry Techniques, Synthetic; Deuterium; Ephedrine; Illicit Drugs; Methamphetamine; Nitrogen Isotopes | 2018 |
Deuteration and selective labeling of alanine methyl groups of β
Topics: Alanine; Animals; Baculoviridae; Deuterium; Insecta; Lipid Bilayers; Micelles; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Receptors, Adrenergic, beta-2; Staining and Labeling | 2018 |
Two weeks of docosahexaenoic acid (DHA) supplementation increases synthesis-secretion kinetics of n-3 polyunsaturated fatty acids compared to 8 weeks of DHA supplementation.
Topics: Alanine; Animals; Carbon Isotopes; Deuterium; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Kinetics; Liver; Male; Rats; Rats, Long-Evans; RNA, Messenger; Time Factors | 2018 |
Effects of deuteration on transamination and oxidation of hyperpolarized
Topics: Alanine; Alanine Transaminase; Amination; Animals; Carbon Isotopes; Deuterium; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Water | 2019 |
An exploration of the methods to determine the protein-specific synthesis and breakdown rates in vivo in humans.
Topics: Adult; Aged; Alanine; Deuterium; Humans; Male; Middle Aged; Muscle Proteins; Muscle, Skeletal; Nitrogen Isotopes; Protein Processing, Post-Translational; Tendons | 2019 |
Application of elemental analysis-coupled isotope ratio mass spectrometry for protein turnover analysis using deuterium labeling: Purification and analysis of hydrogen isotope ratio of non-derivatized protein-bound alanine.
Topics: Alanine; Animals; Deuterium; Deuterium Oxide; Hydrogen; Insulins; Isotope Labeling; Mass Spectrometry; Mice | 2023 |