Compounds > deuterium
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deuterium and 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone

deuterium has been researched along with 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, CI; Hecht, SS; Jordan, KG; Trushin, N1
Castonguay, A; Hecht, SS; Lin, D; Rivenson, A1
Castonguay, A; Hecht, SS; Lin, D1
Hecht, SS; Rivenson, A; Trushin, N1
Hecht, SS; Jalas, JR; Kenney, PM; McIntee, EJ; Peterson, LA; Upadhyaya, P1

Other Studies

5 other study(ies) available for deuterium and 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone

ArticleYear
Effects of deuterium substitution on the tumorigenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in A/J mice.
    Carcinogenesis, 1990, Volume: 11, Issue:6

    Topics: Adenoma; Animals; Carcinogens; Deuterium; DNA; Female; Guanine; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Structure-Activity Relationship

1990
Effects of alpha-deuterium substitution on the tumorigenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in F344 rats.
    Carcinogenesis, 1987, Volume: 8, Issue:2

    Topics: Animals; Biotransformation; Deuterium; DNA Damage; Hydroxylation; Liver Neoplasms; Lung Neoplasms; Neoplasms, Experimental; Nitrosamines; Nose Neoplasms; Rats; Rats, Inbred F344; Structure-Activity Relationship

1987
Effects of alpha-deuterium substitution on the mutagenicity of 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Carcinogenesis, 1983, Volume: 4, Issue:3

    Topics: Deuterium; Mass Spectrometry; Mutagenicity Tests; Mutagens; Mutation; Nitrosamines; Salmonella typhimurium; Structure-Activity Relationship

1983
Evidence supporting the role of DNA pyridyloxobutylation in rat nasal carcinogenesis by tobacco-specific nitrosamines.
    Cancer research, 1994, Mar-01, Volume: 54, Issue:5

    Topics: Alkylation; Animals; Butanones; Carcinogens; Deuterium; DNA Damage; DNA, Neoplasm; Guanine; Male; Nasal Cavity; Nitrosamines; Nose Neoplasms; Olfactory Mucosa; Oxidation-Reduction; Pyridines; Rats; Rats, Inbred F344

1994
Stereospecific deuterium substitution attenuates the tumorigenicity and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Chemical research in toxicology, 2003, Volume: 16, Issue:6

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cytochrome P-450 CYP2A6; Deuterium; DNA; DNA Adducts; Dose-Response Relationship, Drug; Female; Guanine; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Microsomes; Mixed Function Oxygenases; Molecular Structure; Nitrosamines; Stereoisomerism; Structure-Activity Relationship

2003