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deuterium and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

deuterium has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caldera, P; Castagnoli, N; Ottoboni, S; Trevor, A1
Castagnoli, K; Castagnoli, N; Franot, C; Kuttab, S; Mabic, S; Zhao, Z1
Castagnoli, N; Flores, J; Isin, EM; Suleman, NK; Tanko, JM1
Bergh, JJ; Castagnoli, N; Ogunrombi, MO; Petzer, JP; Pretorius, A; Terre'blanche, G1
Cantor, CR; Chou, VP; Langston, JW; Manning-Boğ, AB; Molinari, RJ; Pollock, E; Shchepinov, MS1

Other Studies

5 other study(ies) available for deuterium and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

ArticleYear
Deuterium isotope effect measurements on the interactions of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine with monoamine oxidase B.
    The Journal of biological chemistry, 1989, Aug-15, Volume: 264, Issue:23

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cattle; Chromatography, High Pressure Liquid; Designer Drugs; Deuterium; Isotope Labeling; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mitochondria, Liver; Monoamine Oxidase; Neurotoxins; Protein Binding; Pyridines

1989
Rat liver microsomal enzyme catalyzed oxidation of 1-cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Bioorganic & medicinal chemistry, 1998, Volume: 6, Issue:12

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Deuterium; Kinetics; Male; Microsomes, Liver; Models, Chemical; Models, Molecular; Molecular Conformation; Molecular Structure; NADP; Oxidation-Reduction; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; Substrate Specificity

1998
The tert-butoxyl radical mediated hydrogen atom transfer reactions of the Parkinsonian proneurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and selected tertiary amines.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amines; Carbon; Catalysis; Deuterium; Humans; Hydrogen; Kinetics; Monoamine Oxidase; Neurotoxins; Oxidation-Reduction; Parkinsonian Disorders; Structure-Activity Relationship; tert-Butylhydroperoxide

2008
Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B.
    Bioorganic & medicinal chemistry, 2008, Oct-01, Volume: 16, Issue:19

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Binding Sites; Catalysis; Cattle; Deuterium; Dopamine Agents; Isotope Labeling; Kinetics; Liver; Monoamine Oxidase; Neurotoxins; Oxidation-Reduction; Papio; Parkinson Disease, Secondary; Pyrroles

2008
Isotopic reinforcement of essential polyunsaturated fatty acids diminishes nigrostriatal degeneration in a mouse model of Parkinson's disease.
    Toxicology letters, 2011, Nov-30, Volume: 207, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; alpha-Linolenic Acid; Animals; Cell Death; Corpus Striatum; Deuterium; Disease Models, Animal; Fatty Acids, Unsaturated; Linoleic Acid; Mice; Mice, Inbred C57BL; Nerve Degeneration; Oleic Acid; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Substantia Nigra

2011