destomycin-a has been researched along with arbekacin* in 1 studies
1 other study(ies) available for destomycin-a and arbekacin
Article | Year |
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Inhibition of SV40 DNA replication in vitro by 1-N-acyl-3"-N-(trifluoroacetyl) kanamycin.
A new antiviral aminoglycoside antibiotic, 1-N-eicosanoyl-3''-N-(trifluoroacetyl) kanamycin, was found to inhibit SV40 DNA replication in vitro. Several other aminoglycoside antibiotics examined did not exhibit a significant inhibition of SV40 DNA replication. The elongation of the SV40 DNA strand was profoundly affected by this agent. The degree of inhibition was decreased by increasing the amount of DNA template, but not by increasing the amount of enzyme. The inhibition of SV40 DNA replication is attributed to the interaction between the agent and the DNA template. Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Antiviral Agents; Aphidicolin; Deoxycytidine Monophosphate; Dibekacin; Diterpenes; DNA Replication; DNA, Viral; Haplorhini; Hygromycin B; Kanamycin; Nalidixic Acid; Novobiocin; Simian virus 40; Spectrophotometry; Streptomycin | 1986 |