desoxycorticosterone has been researched along with metyrapone in 122 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 106 (86.89) | 18.7374 |
| 1990's | 6 (4.92) | 18.2507 |
| 2000's | 5 (4.10) | 29.6817 |
| 2010's | 4 (3.28) | 24.3611 |
| 2020's | 1 (0.82) | 2.80 |
| Authors | Studies |
|---|---|
| Berger, ML; Hahner, S; Hammerschmidt, F; Peric-Simov, B; Schirbel, A; Zolle, IM | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Simpson, ER; Williams-Smith, DL | 1 |
| Cammack, R; Williams-Smith, DL | 1 |
| Kovalcík, V; Nosálová, G | 1 |
| Harendt, H; Oelkers, W; Schöneshöfer, M | 1 |
| Ganguly, A; Meikle, AW; Tyler, FH; West, CD | 1 |
| Lafuma, J; Schorn, H; Walter, C | 1 |
| Kato, E; Kitajima, W; Kondo, K; Konishi, K; Matsuki, S; Nakamura, R; Ohguro, T; Oka, M; Ozawa, Y; Saito, I; Saruta, T; Yamagami, K | 1 |
| Dehnen, H; Elsässer, W; Kley, HK; Krüskemper, HL | 1 |
| Oelkers, W; Schefzig, B; Schöneshöfer, M | 1 |
| Barnes, AJ; Cassar, J; Joplin, GF; Kelly, WF; Loizou, S; Mashiter, K; Welbourn, RB; White, M | 1 |
| Franckson, JR; LeJeune-Lenain, C; Wolter, R | 1 |
| Brownie, AC; Bruckheimer, SM; Gallant, S | 1 |
| Bratusch-Marrain, P; Herkner, K; Nowotny, P; Waldhäusl, W | 1 |
| Hauger-Klevene, JH; Vecsei, P | 1 |
| Sherman, B; Waschek, J; Weinberger, M; Wyatt, R | 1 |
| Doe, RP; McMillin, JM; Seal, US | 1 |
| L'age, M; Oelkers, W; Schöneshöfer, M | 1 |
| Critselis, AN; Levenson, SM; Rettura, G; Seifter, E | 1 |
| Greenberg, BP; Wexler, BC | 1 |
| Counsell, RE; Napoli, JL | 1 |
| Levenson, SM; Padawer, J; Rettura, G; Sarkar, D; Seifter, E | 1 |
| Grigorova-Racheva, R; Kolebinov, N; Vasileva, B | 1 |
| Bandyopadhyay, A; Bhattacharyya, SP; Deadhikari, H; Ranjit, M | 1 |
| Kinouchi, T; Shimizu, N; Yoshida, H | 1 |
| Bertetta, C; Bossart, GD; Brown, JW; Carballeira, A; Fishman, LM | 1 |
| Dobrović-Jenik, D; Milković, S | 1 |
| Kiguchi, T; Kobayashi, Y; Ninomiya, I; Nishiguchi, Y; Watanabe, F | 1 |
| de Catanzaro, D; Kerr, TH; Lee, PC | 1 |
| Loyber, I; Palma, JA; Perassi, NI | 1 |
| Carballeira, A; Cheng, SC; Fishman, LM | 2 |
| Borsch, E; Dransfeld, H | 1 |
| Bledsoe, T; Island, DP; Liddle, GW | 1 |
| Biglieri, EG; Brust, N; Herron, MA | 1 |
| Daneels, R; Van der Straeten, M; Verdonck, G; Vermeulen, A | 1 |
| Nakagawa, K; Nankin, H; Nugent, CA; Strott, CA | 1 |
| Krass, ME; LaBella, FS; Pollock, JJ | 1 |
| Malchow-Creutzburg, H | 1 |
| Miura, K | 1 |
| Birmingham, MK; Kraulis, I; Lantos, CP; Li, MP; Traikov, H | 1 |
| New, MI; Seaman, MP | 1 |
| Brownie, AC; Colby, HD; Gallant, S; Skelton, FR | 1 |
| Sauer, LA | 1 |
| Buus, O; Nielsen, E; Toft, H | 1 |
| Bartová, A; Birmingham, MK; Tibagong, M | 1 |
| Genest, J; Kuchel, O; Mancheno-Rico, E; Nowaczynski, W; Seth, K | 1 |
| Baumann, K; Müller, J | 1 |
| Brown, RD; Liddle, GW; Strott, CA | 1 |
| Cooper, DY; Levin, SS; Rosenthal, O; Schleyer, H | 1 |
| New, MI; Peterson, RE; Siegal, EJ | 1 |
| Diedrichsen, G; Lommer, D; Lommer, I | 1 |
| Gardner, LI; Gregory, T; Mendilaharzu, H | 1 |
| Speller, PJ; Streeten, DH | 1 |
| Péron, FG; Sanzari, NP | 1 |
| Ertel, RJ; Ungar, F | 2 |
| Hall, PF; Young, DG | 1 |
| Flemming, K; Seydewitz, V | 1 |
| Rao, PD; Subhedar, N | 1 |
| Coimbra, A; Magalhães, MC; Magalhães, MM | 1 |
| Dupouy, JP | 1 |
| Lunardi, J; Satre, M; Vignais, PV | 1 |
| Sladek, NE | 1 |
| Doret, AM; Kohlberg, IJ; Paunier, L; Sizonenko, PC | 1 |
| Jeffries, CD; Wilkins, J | 1 |
| Ho-Kim, MA; Tremblay, RR | 1 |
| Satre, M; Vignais, PV | 1 |
| Suzuki, Y | 1 |
| Blichert-Toft, M; Kålund Jensen, H | 1 |
| Dahl, V; de Nicola, AF | 1 |
| Adlin, EV; Channick, BJ; Marks, AD | 1 |
| Kley, HK; Krüskemper, HL | 1 |
| Bethge, H; Hackenberg, K; Heesen, D; Mies, R; Winkelmann, W | 1 |
| Crane, MG; Harris, JJ; Hoegel, C | 1 |
| Brownie, AC; Colby, HD; Skelton, FR | 1 |
| Bryson, MJ; Sweat, ML; Young, RB | 2 |
| Brownie, AC; Colby, HD | 1 |
| Channick, BJ; Marks, AD; Tuft, L | 1 |
| Garland, M; Jellinck, PH; McRitchie, D | 1 |
| Diczfalusy, E; Shimao, S; Solomon, S; Wiqvist, N | 1 |
| Hannah, DM; Sprunt, JG | 1 |
| Birmingham, MK; De Nicola, AF; Traikov, H | 1 |
| Hutchings, MP; Jubiz, W; Meikle, AW; Tyler, FH; West, CD | 1 |
| O'Donnell, VJ; Williamson, DG | 1 |
| Dominguez, OV | 1 |
| Birmingham, MK; Kraulis, I | 1 |
| Hicks, R | 1 |
| Ungar, F; Van Pilsum, JF | 1 |
| Cope, CL; Dennis, PM; Pearson, J | 1 |
| Jull, JW | 1 |
| Goswami, SV; Sundararaj, BI | 1 |
| Morris, B; Morris, R | 1 |
| Levine, LS; New, MI; Sonino, N; Vecsei, P | 1 |
| Fukuchi, S; Haruyama, K; Toki, T; Yamazaki, M | 1 |
| Antonipillai, I; Frasier, SD; Horton, R; Moghissi, E | 1 |
| Bullock, G; Rahal, S; Senciall, IR | 1 |
| Levine, LS; New, MI; Sonino, N | 1 |
| Chow, D; Levine, LS; New, MI; Sonino, N | 1 |
| Cassar, J; Joplin, GF; Kelly, WF; Loizou, S; Mashiter, K | 1 |
| Chrousos, GP; Jeffries, S; Pang, S; Riddick, L | 1 |
| Ashwell, JD; Papadopoulos, V; Vacchio, MS | 1 |
| Jefcoate, CR; McNamara, BC; Yamazaki, T | 1 |
| Cozza, EN; Foecking, MF; Gomez-Sanchez, CE; Gomez-Sanchez, EP; Morita, H; Zhou, MY | 1 |
| Morian, KR; Rowland, NE | 1 |
| Brown, JW; Fishman, LM | 1 |
| Kao, PC; Lacey, JM; Machacek, DA; Magera, MJ; Rinaldo, P | 1 |
| Harris, DS; Jones, RT; Mendelson, JE; Reus, VI; Wolkowitz, OM | 1 |
| DOMINGUEZ, OV; SAMUELS, LT | 1 |
| SHICHINOHE, M | 1 |
| KUNII, Y; OGAWA, K; WATANABE, Y | 1 |
| MEDOC, J; TOUYABOGGIANO, JJ | 1 |
| DVORNIK, D; GAUDRY, R; GIVNER, ML; KRAML, M | 1 |
| DONOSO, AO; STEFANO, FJ | 1 |
| HANKE, W; WEBER, K | 1 |
| Cadirci, E; Gocer, F; Hacimuftuoglu, A; Halici, Z; Keles, S; Suleyman, H | 1 |
| Gómez, Y; Hinojosa, L; Romano, MC; Valdez, RA; Willms, K | 1 |
| Dhungana, S; Goeders, NE; Guerin, GF; Runyon, SP; Schmoutz, CD | 1 |
| Fujii, Y; Kouchi, M; Matsumoto, I; Miyawaki, I; Tochitani, T; Yamada, T; Yamashita, A | 1 |
| Dezsi, G; Harris, G; Jones, NC; O'Brien, TJ; Ozturk, E; Paul, C | 1 |
3 trial(s) available for desoxycorticosterone and metyrapone
| Article | Year |
|---|---|
Effects of inhaled beclomethasone dipropionate and alternate-day prednisone on pituitary-adrenal function in children with chronic asthma.
Topics: Administration, Oral; Adolescent; Aerosols; Asthma; Beclomethasone; Child; Clinical Trials as Topic; Desoxycorticosterone; Drug Administration Schedule; Drug Therapy, Combination; Humans; Hydrocortisone; Metyrapone; Pituitary-Adrenal System; Prednisone | 1978 |
Comparison of adrenocorticotropin and adrenal steroid responses to corticotropin-releasing hormone versus metyrapone testing in patients with hypopituitarism.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Child; Child, Preschool; Corticotropin-Releasing Hormone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hypopituitarism; Hypothalamo-Hypophyseal System; Male; Metyrapone; Pituitary-Adrenal System | 1994 |
Altering cortisol level does not change the pleasurable effects of methamphetamine in humans.
Topics: Adult; Affect; Blood Pressure; Central Nervous System Stimulants; Cross-Over Studies; Dehydroepiandrosterone; Desoxycorticosterone; Double-Blind Method; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Heart Rate; Humans; Hydrocortisone; Male; Methamphetamine; Metyrapone; Respiration; Surveys and Questionnaires; Time Factors | 2003 |
119 other study(ies) available for desoxycorticosterone and metyrapone
| Article | Year |
|---|---|
New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues.
Topics: Adrenal Cortex; Animals; Binding Sites; Etomidate; Humans; Hydroxylation; Iodine Radioisotopes; Kinetics; Male; Molecular Structure; Rats; Rats, Wistar; Stereoisomerism; Steroid 11-beta-Hydroxylase; Structure-Activity Relationship | 2008 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Electron paramagnetic resonance spectra of mitochondrial and microsomal cytochrome P-450 from the rat adrenal.
Topics: Adrenal Glands; Aminoglutethimide; Animals; Calcium; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Electron Spin Resonance Spectroscopy; Female; Hydrogen-Ion Concentration; Isocitrates; Metyrapone; Microsomes; Mitochondria; Pregnenolone; Rats; Succinates | 1976 |
Oxidation-reduction potentials of cytochromes P-450 and ferredoxin in the bovine adrenal. Their modification by substrates and inhibitors.
Topics: Adrenal Glands; Aminoglutethimide; Animals; Cattle; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Electron Spin Resonance Spectroscopy; Ferredoxins; Hydrogen-Ion Concentration; Hydroxycholesterols; Metyrapone; Microsomes; Mitochondria; Oxidation-Reduction; Potentiometry; Protein Binding | 1977 |
The effect of adrenal cortical hormones on the calcium content of rat aorta.
Topics: Adrenal Cortex Hormones; Animals; Aorta; Calcium; Desoxycorticosterone; Female; Male; Metyrapone; Prednisone; Rats; Reserpine; Stimulation, Chemical | 1975 |
Radioimmunoassay of serum deoxycorticosterone: normal values and changes of serum deoxycorticosterone after adrenal stimulation.
Topics: Acromegaly; Addison Disease; Adrenocorticotropic Hormone; Adult; Chromatography, Paper; Desoxycorticosterone; Female; Humans; Insulin; Male; Metyrapone; Ovulation; Pituitary Diseases; Protein Binding; Radioimmunoassay; Sex Factors; Tritium | 1975 |
Assessment of 11beta-hydroxylase activity with plasma corticosterone, deoxycorticosterone, cortisol, and deoxycortisol: role of ACTH and angiotensin.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Circadian Rhythm; Corticosterone; Cortodoxone; Cushing Syndrome; Desoxycorticosterone; Dexamethasone; Diet, Sodium-Restricted; Furosemide; Humans; Hydrocortisone; Metyrapone; Posture; Renin; Steroid Hydroxylases | 1977 |
The effect of corticosteroids on alveolar macrophage activity.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aerosols; Aldosterone; Animals; Biological Transport; Desoxycorticosterone; Hydrocortisone; Iron; Macrophages; Male; Metyrapone; Pulmonary Alveoli; Rats; Spironolactone; Triamcinolone Acetonide | 1977 |
Hypertension induced by adrenocortical dysfunction--hypertension in 17 alpha-hydroxylase deficiency and metopirone-induced hypertension.
Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Animals; Cushing Syndrome; Desoxycorticosterone; Dexamethasone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Metyrapone; Middle Aged; Rats; Renin; Steroid Hydroxylases | 1978 |
Evaluation of adrenal function in rats by the measurement of urinary free corticosterone, free aldosterone and free 11-deoxycorticosterone.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Animals; Cold Temperature; Corticosterone; Desoxycorticosterone; Dexamethasone; Ether; Hunger; Male; Methods; Metyrapone; Rats; Reserpine; Stress, Physiological | 1978 |
Evidence of adrenal 18-hydroxylase inhibition by metyrapone in man.
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Desoxycorticosterone; Humans; Male; Metyrapone; Steroid Hydroxylases | 1979 |
Cushing's syndrome due to adrenocortical carcinoma - a comphrensive clinical and biochemical study of patients treated by surgery and chemotherapy.
Topics: 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Carcinoma; Cortodoxone; Cushing Syndrome; Desoxycorticosterone; Electrolytes; Estradiol; Female; Humans; Hydrocortisone; Luteinizing Hormone; Metyrapone; Middle Aged; Mitotane; Pregnanetriol; Testosterone | 1979 |
Kinetics of plasma corticosteroids during metyrapone infusion in man.
Topics: Adolescent; Adrenocorticotropic Hormone; Aldosterone; Child; Child, Preschool; Corticosterone; Cortodoxone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Kinetics; Male; Metyrapone; Pregnenediones | 1979 |
The use of high-pressure liquid chromatography in the simultaneous assay of 11beta-hydroxylase and 18-hydroxylase in zona fasciculata-reticularis tissue of the rat adrenal cortex.
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex; Animals; Chromatography, High Pressure Liquid; Corticosterone; Desoxycorticosterone; Female; Metyrapone; Mitochondria; Rats; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases | 1978 |
Combined 17 alpha- and 18-hydroxylase deficiency associated with complete male pseudohermaphroditism and hypoaldosteronism.
Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Corticosterone; Desoxycorticosterone; Disorders of Sex Development; Humans; Male; Metyrapone; Middle Aged; Steroid Hydroxylases; Steroids | 1978 |
Metyrapone effect on blood pressure and deoxycorticosterone levels in the rat.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Male; Metyrapone; Rats; Steroid 11-beta-Hydroxylase | 1978 |
Effect of oral estramustine phosphate on pituitary, gonadal, and adrenal function in the green monkey (Cercopithecus aethiops sabaeus).
Topics: Administration, Oral; Adrenal Glands; Animals; Chlorocebus aethiops; Desoxycorticosterone; Estramustine; Gonadotropin-Releasing Hormone; Haplorhini; Luteinizing Hormone; Male; Metyrapone; Nitrogen Mustard Compounds; Pituitary Gland; Testis; Testosterone; Transcortin | 1977 |
Short time kinetics of deoxycorticosterone, deoxycortisol, corticosterone and cortisol during single dose metyrapone test.
Topics: Administration, Oral; Adrenal Cortex; Adrenal Cortex Function Tests; Adrenal Cortex Hormones; Adrenal Glands; Adult; Corticosterone; Cortodoxone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Male; Metyrapone; Mixed Function Oxygenases; Pituitary-Adrenal Function Tests; Time Factors | 1977 |
Inhibitory effect of metyrapone and deoxycorticosterone on C3H breast adenocarcinoma.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Desoxycorticosterone; Immunosuppression Therapy; Metyrapone; Mice; Mice, Inbred C3H; Neoplasms, Experimental | 1977 |
Metyrapone-induced cardiovascular degenerative changes in non-arteriosclerotic and arteriosclerotic rats.
Topics: Adrenal Glands; Animals; Arteries; Arteriosclerosis; Blood Urea Nitrogen; Body Weight; Cardiovascular Diseases; Desoxycorticosterone; Female; Hypertension; Lipids; Male; Metyrapone; Organ Size; Rats | 1978 |
New inhibitors of steroid 11beta-hydroxylase. Structure--activity relationship studies of metyrapone-like compounds.
Topics: Adrenal Cortex; Animals; Cattle; Corticosterone; Desoxycorticosterone; In Vitro Techniques; Kinetics; Metyrapone; Mitochondria; Steroid Hydroxylases; Structure-Activity Relationship | 1977 |
Inhibition of tumor growth by metyrapone and desoxycorticosterone.
Topics: Adenocarcinoma; Animals; Desoxycorticosterone; Female; Mammary Neoplasms, Experimental; Metyrapone; Mice; Mice, Inbred C3H; Neoplasms, Experimental | 1976 |
[Changes in the corticosteroids and their alpha-ketol metabolites in the urine of hypertension patients treated with metopirons].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aldosterone; Circadian Rhythm; Cortodoxone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hypertension; Male; Metyrapone; Middle Aged; Tetrahydrocortisone | 1975 |
Adrenocortical influence on histokinetics and lipid components of uropygial gland of immature chick.
Topics: Adrenal Cortex Hormones; Animals; Chickens; Corticosterone; Desoxycorticosterone; Lipid Metabolism; Male; Metyrapone; Sebaceous Glands | 1990 |
[Clinical significance of serum 11-deoxycorticosterone analysis in endocrine tests of the adrenal cortex].
Topics: Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Desoxycorticosterone; Dexamethasone; Humans; Hypertension; Metyrapone; Radioimmunoassay; Reference Values | 1989 |
The adrenal gland of stranded whales (Kogia breviceps and Mesoplodon europaeus): in vitro modulation of mitochondrial steroid enzyme activities.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cattle; Cells, Cultured; Cetacea; Cholesterol; Cyclic AMP; Desoxycorticosterone; Hydroxylation; Metyrapone; Mitochondria; NADP; Rats; Rats, Inbred BUF; Species Specificity; Succinates; Whales | 1987 |
Regulation of fetal Na+/K+-ATPase in rat kidney by corticosteroids.
Topics: 4-Nitrophenylphosphatase; Adrenal Cortex Hormones; Adrenalectomy; Animals; Ca(2+) Mg(2+)-ATPase; Desoxycorticosterone; Embryonic and Fetal Development; Female; Kidney; Metyrapone; Pregnancy; Rats; Rats, Inbred F344; Sodium-Potassium-Exchanging ATPase | 1988 |
An alternative metabolic pathway of 11-deoxycorticosterone in bovine adrenal in vitro: evidence for the presence of a pathway of 11-deoxycorticosterone oxidation at 19-position.
Topics: Adrenal Glands; Animals; Carbon Monoxide; Cattle; Cytochrome P-450 Enzyme System; Desoxycorticosterone; In Vitro Techniques; Kinetics; Metyrapone; Oxidation-Reduction; Potassium Cyanide | 1987 |
Facilitation of sexual receptivity in female mice through blockade of adrenal 11 beta-hydroxylase.
Topics: Animals; Corticosterone; Desoxycorticosterone; Female; Metyrapone; Mice; Posture; Progesterone; Sexual Behavior, Animal; Steroid 11-beta-Hydroxylase | 1985 |
Role of adrenal glands in the serum protein changes produced by resection or stimulation of the olfactory bulbs in the rat.
Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Alpha-Globulins; Animals; Ascorbic Acid; Beta-Globulins; Blood Protein Electrophoresis; Blood Proteins; Corticosterone; Desoxycorticosterone; Electric Stimulation; Epinephrine; Female; gamma-Globulins; Humans; Limbic System; Metyrapone; Parietal Lobe; Rats; Serum Albumin | 1971 |
Sites of metyrapone inhibition of steroid biosynthesis by rat adrenal mitochondria.
Topics: Adrenal Glands; Animals; Carbon Radioisotopes; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Depression, Chemical; Desoxycorticosterone; Dose-Response Relationship, Drug; Glucose-6-Phosphatase; Hydroxylation; Male; Metyrapone; Mitochondria; NADH, NADPH Oxidoreductases; Pregnenolone; Rats; Receptors, Drug; Time Factors; Tritium | 1974 |
[Mechanism of increased toxicity of k-strophanthin in adrenalectomized rats].
Topics: Adenosine Triphosphatases; Adrenalectomy; Animals; Brain; Desoxycorticosterone; Enzyme Activation; Guinea Pigs; Kidney; Metyrapone; Myocardium; Potassium; Rats; Sodium; Strophanthins | 1970 |
Studies of the mechanism through which sodium depletion increases aldosterone biosynthesis in man.
Topics: Adrenocorticotropic Hormone; Aldosterone; Carbon Isotopes; Chromatography, Paper; Corticosterone; Desoxycorticosterone; Dexamethasone; Female; Humans; Hydrocortisone; Hypopituitarism; In Vitro Techniques; Metyrapone; Radioisotope Dilution Technique; Radiometry; Secretory Rate; Sodium; Triamterene; Tritium; Urine | 1966 |
17-hydroxylation deficiency in man.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Corticosterone; Desoxycorticosterone; Diet, Sodium-Restricted; Female; Humans; Hydroxyprogesterones; Metabolism, Inborn Errors; Metyrapone; Mixed Function Oxygenases; Natriuresis; Potassium; Progesterone | 1966 |
Evaluation of the efficiency of 11-beta-hydroxylation of 11-deoxycortisol in human subjects.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Cushing Syndrome; Desoxycorticosterone; Estrogens; Humans; Hydrocortisone; Metyrapone; Mixed Function Oxygenases; Pituitary-Adrenal System; Progesterone; Secretory Rate | 1967 |
A phenylalanine-lysine-vasopressin test of ACTH release.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Adult; Child; Desoxycorticosterone; Female; Humans; Hydrocortisone; Lysine; Male; Metyrapone; Middle Aged; Phenylalanine; Pituitary Function Tests; Pituitary Gland; Vasopressins | 1967 |
Stimulation of adrenal activity by the administration of corticosterone to rats chronically treated with amphenone or methapyrapone.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Ascorbic Acid; Chromatography, Thin Layer; Corticosterone; Desoxycorticosterone; Hypothalamo-Hypophyseal System; Metyrapone; Organ Size; Propiophenones; Rats | 1966 |
[The metopirone test for the determination of the hypophysis-adrenal cortex reserve].
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Desoxycorticosterone; Humans; Metyrapone; Pituitary-Adrenal Function Tests | 1966 |
[Patterns of adrenal steroids present in the blood].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Blood Proteins; Corticosterone; Cushing Syndrome; Desoxycorticosterone; Diabetes Mellitus; Eosinophils; Erythrocytes; Estrogens; Female; Glucocorticoids; Humans; Hydrocortisone; Male; Metyrapone; Pregnancy | 1967 |
The reduction of SU-4885 by adrenal glands and other tissues and its inhibition by ACTH.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Anura; Boron; Desoxycorticosterone; Diaphragm; Kidney; Liver; Metyrapone; Oxidation-Reduction; Rats; Spectrophotometry; Time Factors | 1968 |
Secretion rates of cortisol and aldosterone precursors in various forms of congenital adrenal hyperplasia.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Child; Child, Preschool; Corticosterone; Desoxycorticosterone; Dexamethasone; Diet; Female; Humans; Hydrocortisone; Hyperplasia; Hypertension; Male; Metabolism, Inborn Errors; Metyrapone; Mixed Function Oxygenases; Potassium; Pregnanetriol; Secretory Rate; Sodium | 1970 |
Some studies on the effect of androgens on adrenal cortical function of rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Anabolic Agents; Animals; Corticosterone; Cytochromes; Desoxycorticosterone; Female; Glucocorticoids; Methyltestosterone; Metyrapone; Mitochondria; Mixed Function Oxygenases; Organ Size; Progesterone; Rats; Spectrophotometry | 1970 |
Steroid hydroxylations in rat adrenal mitochondria. II. Competition between energy-linked transhydrogenase-dependent steroid hydroxylation and oxidative phosphorylation for high-energy intermediates and NADH.
Topics: Adenosine Triphosphate; Adrenal Glands; Animals; Corticosterone; Desoxycorticosterone; Electron Transport; Hydroxybutyrates; Ketoglutaric Acids; Male; Malonates; Metyrapone; Mitochondria; NAD; Oxidative Phosphorylation; Oxidoreductases; Rats | 1970 |
Vasopressin in the diagnostic evaluation of pituitary and hypothalamic function.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aged; Circadian Rhythm; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hypopituitarism; Male; Metyrapone; Middle Aged; Pituitary Diseases; Pituitary-Adrenal Function Tests; Vasopressins | 1971 |
Steroid-mediated stimulation of aerobic glycolysis by intact mouse adrenal glands in vitro.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aerobiosis; Aminoglutethimide; Analysis of Variance; Animals; Carbon Isotopes; Chromatography, Paper; Corticosterone; Desoxycorticosterone; Fluorescence; Glycolysis; Hydroxyprogesterones; In Vitro Techniques; Lactates; Male; Metyrapone; Mice; Pregnanes; Progesterone; Pyruvates; Spectrophotometry; Ultraviolet Rays | 1971 |
Procedure for simultaneous determination of secretion rates of deoxycorticosterone and corticosterone by double-isotope derivative assay.
Topics: 17-Hydroxycorticosteroids; Acetates; Acylation; Anhydrides; Carbon Isotopes; Chromatography; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Corticosterone; Desoxycorticosterone; Female; Humans; Hydrazones; Male; Mathematics; Methods; Metyrapone; Nitrobenzenes; Potassium; Pregnanes; Secretory Rate; Silicon Dioxide; Sodium; Tritium | 1972 |
Effect of potassium intake on the final steps of aldosterone biosynthesis in the rat. II. 11 -hydroxylation.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Chromatography, Paper; Corticosterone; Depression, Chemical; Desoxycorticosterone; Hydrocortisone; Hydroxycorticosteroids; Hydroxylation; Male; Metyrapone; Mitochondria; Mixed Function Oxygenases; Potassium; Proteins; Rats; Stimulation, Chemical; Time Factors; Tritium | 1972 |
Site of stimulation of aldosterone biosynthesis by angiotensin and potassium.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Desoxycorticosterone; Dexamethasone; Humans; Hydrocortisone; Hypopituitarism; Metyrapone; Potassium; Stimulation, Chemical; Tritium | 1972 |
Haem protein P-450 from the adrenal cortex: interaction with steroids and the hydroxylation reaction.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Carbon Isotopes; Chemistry, Organic; Cholesterol; Corticosterone; Cortisone; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Electron Spin Resonance Spectroscopy; Hydroxylation; Metyrapone; Mitochondria; Organic Chemistry Phenomena; Pregnenolone; Progesterone; Pseudomonas | 1972 |
Dexamethasone-suppressible hyperaldosteronism.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Aldosterone; Corticosterone; Desoxycorticosterone; Dexamethasone; Diet; Diet, Sodium-Restricted; Follow-Up Studies; Humans; Hydrocortisone; Hyperaldosteronism; Male; Metyrapone; Pregnanetriol; Renin; Secretory Rate | 1973 |
In-vitro corticosteroid synthesis in rat adrenals. I. Results indicating (an) alternative pathway(s) of synthesis without the intermediates cholesterol, pregnenolone and progesterone.
Topics: Acetates; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Cholesterol; Corticosterone; Desoxycorticosterone; In Vitro Techniques; Metyrapone; Pregnenolone; Progesterone; Rats; Tritium | 1973 |
Iatrogenic Cushing's disease in a boy after misdiagnosis of salt-losing virilizing adrenal hyperplasia: impaired metyrapone response with failure of catch-up growth.
Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Adrenocorticotropic Hormone; Body Weight; Bone Development; Child; Child, Preschool; Cushing Syndrome; Desoxycorticosterone; Diagnosis, Differential; Diagnostic Errors; Fludrocortisone; Glucocorticoids; Growth Disorders; Growth Hormone; Humans; Hydrocortisone; Infant; Infant, Newborn; Insulin; Male; Methylprednisolone; Metyrapone; Mineralocorticoids; Pituitary-Adrenal Function Tests | 1973 |
The role of mineralocorticoids in the pathogenesis of hypokalemic periodic paralysis.
Topics: Adult; Aldosterone; Angiotensin II; Desoxycorticosterone; Humans; Hydrocortisone; Hyperaldosteronism; Hypokalemia; Male; Metyrapone; Mineralocorticoids; Paralysis; Periodicity; Sodium; Spironolactone | 1974 |
Influence of metopirone on substrate-supported hydroxylation of DOC by rat adrenal mitochondria.
Topics: Adrenal Glands; Animals; Citrates; Cytochromes; Desoxycorticosterone; Electron Transport; Fluorometry; In Vitro Techniques; Ketoglutaric Acids; Male; Metyrapone; Mitochondria; NADP; Nucleotides; Oxygen Consumption; Rats; Succinates | 1966 |
20-alpha-Hydroxysteroid dehydrogenase and reductive pathways in mouse adrenal glands in vitro.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Carbon Isotopes; Chromatography, Thin Layer; Crystallization; Desoxycorticosterone; Female; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Metyrapone; Mice; NADP; Pregnanediol; Pregnenolone; Progesterone | 1968 |
Steroid hydroxylation in bovine adrenocortical mitochondria. Competition between side-chain cleavage of cholesterol and 11 beta hydroxylation.
Topics: Adrenal Glands; Animals; Calcium; Carbon Isotopes; Cattle; Cell Fractionation; Cholesterol; Corticosterone; Cytochromes; Depression, Chemical; Desoxycorticosterone; Feedback; In Vitro Techniques; Kinetics; Metyrapone; Mitochondria; Mixed Function Oxygenases; NADP; Pregnenolone | 1971 |
Metabolism of (4-14C) cholesterol by human adrenal glands in vitro and its inhibition by metyrapone.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Hyperfunction; Adult; Androstenedione; Carbon Radioisotopes; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Corticosterone; Depression, Chemical; Desoxycorticosterone; Female; Humans; Hydrocortisone; In Vitro Techniques; Metyrapone; Middle Aged; Pregnenolone; Progesterone; Tritium | 1974 |
A study of the inhibition by cysteamine on the steroid 11 beta-hydroxylation.
Topics: Adrenal Cortex; Adrenal Glands; Animals; Corticosterone; Cysteamine; Desoxycorticosterone; Hydroxylation; Metyrapone; Rats; Steroid Hydroxylases; Structure-Activity Relationship | 1974 |
Effects of some corticosteroids and metopirone on the corpuscles of Stannius and interrenal gland of the catfish, Heteropneustes fossilis (Bloch).
Topics: Adrenal Glands; Animals; Cell Nucleus; Desoxycorticosterone; Endocrine Glands; Female; Fishes; Hydrocortisone; Interrenal Gland; Kidney; Male; Metyrapone; Time Factors | 1974 |
An electron microscope autoradiographic study of DOC conversion to corticosterone in the rat adrenal cortex.
Topics: Adrenal Cortex; Adrenal Glands; Animals; Corticosterone; Desoxycorticosterone; Endoplasmic Reticulum; Golgi Apparatus; Histocytochemistry; Kinetics; Lipid Metabolism; Lysosomes; Male; Metyrapone; Microscopy, Electron; Mitochondria; Rats; Time Factors; Tritium | 1974 |
Sites of the negative feedback action of corticosteroids on the hypothalamo-hypophisial system of the rat fetus.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Binding Sites; Body Weight; Corticosterone; Desoxycorticosterone; Dexamethasone; Feedback; Female; Fetus; Hypothalamo-Hypophyseal System; Maternal-Fetal Exchange; Metyrapone; Organ Size; Pregnancy; Rats | 1974 |
( 3 H)metyrapol as a tool for studies of interactions of deoxycorticosterone with adrenal cortex mitochondria.
Topics: Adrenal Glands; Androstenes; Animals; Binding Sites; Binding, Competitive; Borohydrides; Carbon Monoxide; Cattle; Chemical Phenomena; Chemistry; Desoxycorticosterone; Hydroxylation; Ketosteroids; Kinetics; Metyrapone; Mitochondria; Oxygen Consumption; Sulfites; Tritium | 1972 |
Therapeutic efficacy of cyclophosphamide as a function of inhibition of its metabolism.
Topics: Alkylation; Animals; Azaguanine; Binding, Competitive; Carcinoma 256, Walker; Cyclophosphamide; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; Gonadal Steroid Hormones; Male; Meperidine; Mercaptopurine; Metyrapone; Microsomes, Liver; Morphine; Phenacetin; Proadifen; Probenecid; Quinine; Rats | 1972 |
Assessment of the pituitary adrenal cortex axis in children by a single dose metyrapone test.
Topics: Adolescent; Adrenal Glands; Anorexia Nervosa; Cerebral Ventricle Neoplasms; Child; Child, Preschool; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hypernatremia; Hypoglycemia; Hypothalamo-Hypophyseal System; Infant; Male; Metyrapone; Pituitary-Adrenal Function Tests; Stimulation, Chemical | 1972 |
Effect of exogenous steroids and inhibitors of steroidogenesis on endotoxin shock.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aminoglutethimide; Androstenedione; Animals; Butanones; Corticosterone; Desoxycorticosterone; Endotoxins; Hydrocortisone; Hydroxyprogesterones; Lethal Dose 50; Male; Metyrapone; Mice; Mice, Inbred ICR; Pregnenes; Pregnenolone; Progesterone; Shock, Septic | 1973 |
[Effects of metopirone on plasma deoxycorticosterone, 11-deoxycortisol, and cortisol in the human being].
Topics: Chromatography, Paper; Chromatography, Thin Layer; Desoxycorticosterone; Humans; Hydrocortisone; Isotope Labeling; Metyrapone; Protein Binding; Radionuclide Imaging; Tritium | 1973 |
Steroid 11beta-hydroxylation in beef adrenal cortex mitochondria. Binding affinity and capacity of specific (14C)steroids and for (3H)metyrapol, an inhibitor of the 11beta-hydroxylation reaction.
Topics: Adrenal Glands; Androstenedione; Animals; Binding Sites; Binding, Competitive; Carbon Radioisotopes; Cattle; Cholesterol; Cyclohexanes; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Hydroxylation; Metyrapone; Microsomes; Mitochondria; Nitriles; Steroid Hydroxylases; Steroids; Structure-Activity Relationship; Testosterone; Thermodynamics; Tritium | 1974 |
Sex difference in hypertensive action of metopirone in relation to its plasma levels in the rat.
Topics: Administration, Oral; Adrenal Glands; Animals; Blood Pressure; Body Weight; Chromatography, Thin Layer; Corticosterone; Desoxycorticosterone; Female; Half-Life; Injections, Intravenous; Male; Metyrapone; Plethysmography; Rats; Sex Factors; Time Factors | 1972 |
Intravenous metyrapone test.
Topics: Adolescent; Adult; Aged; Desoxycorticosterone; Female; Humans; Hydrocortisone; Injections, Intravenous; Male; Methods; Metyrapone; Middle Aged; Stimulation, Chemical; Time Factors | 1972 |
Acute effects of SU-4885 and its reduced derivative (SU-5236) on the adrenocortical secretion of the rat.
Topics: Adrenal Glands; Aldosterone; Animals; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Female; Injections, Intravenous; Metyrapone; Oxidation-Reduction; Progesterone; Rats; Secretory Rate; Spectrophotometry; Time Factors; Tritium; Ultraviolet Rays | 1971 |
Effect of metyrapone on plasma renin activity in dogs.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Dexamethasone; Diet, Sodium-Restricted; Disease Models, Animal; Dogs; Female; Furosemide; Hypertension; Male; Metyrapone; Mixed Function Oxygenases; Potassium; Renin; Stimulation, Chemical; Urine | 1971 |
A simplified metyrapone test with simultaneous determination of plasma 11-hydroxy-and 11-desoxycorticosteroids (author's transl).
Topics: 11-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adult; Chemistry Techniques, Analytical; Desoxycorticosterone; Humans; Metyrapone; Pituitary Gland; Plasma; Protein Binding; Radiochemistry; Solutions; Solvents | 1971 |
[Secretion of cortisol, corticosterone, and 11-desoxycortisol in patients with primary adrenal gland insufficiency under basal conditions and during the metopirone test].
Topics: Adrenal Insufficiency; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Humans; Hydrocortisone; Metyrapone; Tritium | 1971 |
Deoxycorticosterone secretion rates before and during metyrapone administration in normal subjects.
Topics: 17-Ketosteroids; Adrenal Glands; Adult; Bile; Carbon Isotopes; Cholecystectomy; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Coloring Agents; Desoxycorticosterone; Feces; Female; Humans; Male; Metyrapone; Radioisotope Dilution Technique; Secretory Rate; Spectrophotometry; Tritium | 1967 |
Metopirone-induced hypertension in the rat.
Topics: Adrenal Glands; Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Female; Hypernatremia; Hypertension; Hypokalemia; Kidney Glomerulus; Metyrapone; Mixed Function Oxygenases; Necrosis; Rats | 1970 |
Two adrenal gland cytochrome P-450 entities evidenced by metyrapone-induced spectra.
Topics: Adrenal Glands; Animals; Cattle; Cytochromes; Desoxycorticosterone; Hydroxyprogesterones; Metyrapone; Microsomes; Mitochondria; Spectrum Analysis | 1970 |
A comparison of the effects produced by metyrapone and its reduced metabolitonheadrenal 11-beta-hydroxylase systm in the rat.
Topics: 1-Propanol; Adrenal Glands; Animals; Carbon Isotopes; Desoxycorticosterone; Female; In Vitro Techniques; Metyrapone; Mitochondria; Mixed Function Oxygenases; Pyridines; Rats | 1970 |
Long-term corticosteroid therapy in chronic intractable asthmatic patients.
Topics: 17-Hydroxycorticosteroids; Adult; Aged; Asthma; Blood Coagulation Tests; Blood Glucose; Body Weight; Desoxycorticosterone; Ecchymosis; Female; Hirsutism; Humans; Hydrocortisone; Hypertension; Male; Metyrapone; Middle Aged; Osteoporosis; Pituitary-Adrenal Function Tests; Time Factors; Triamcinolone; Water-Electrolyte Balance | 1971 |
Effect of metopirone and 3-(1,2,3,4-tetrahydro-1-oxo-2-naphthyl)-pyridine on the metabolism of corticosteroids and DMBA in relation to adrenal necrosis.
Topics: Adrenal Gland Diseases; Adrenal Glands; Animals; Benz(a)Anthracenes; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Desoxycorticosterone; Female; Metyrapone; Naphthalenes; Necrosis; Progesterone; Pyridines; Rats | 1968 |
The effect of Metopirone (SU-4885) on the metabolism of progesterone by the perfused previable human fetus.
Topics: Adrenal Glands; Chromatography; Desoxycorticosterone; Female; Fetus; Humans; Intestinal Mucosa; Liver; Lung; Metyrapone; Perfusion; Pregnancy; Pregnanes; Progesterone; Tritium | 1968 |
A comparison of of the potency of some 11beta-hydroxylase inhibitors using rat and human adrenal tissue.
Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Animals; Carbon Isotopes; Corticosterone; Depression, Chemical; Desoxycorticosterone; Humans; In Vitro Techniques; Metyrapone; Mixed Function Oxygenases; Phenethylamines; Rats | 1968 |
Effects of 2-methyl-1,2-bis(3'-pyridyl 1-propanol (reduced metopirone) on the formation of 18-hydroxylated steroids by quartered rat adrenals.
Topics: Adrenal Glands; Aldosterone; Animals; Antimetabolites; Carbon Isotopes; Corticosterone; Desoxycorticosterone; In Vitro Techniques; Metyrapone; Rats; Tritium | 1969 |
Studies of the oxidation state of partially purified adrenal cortex mitochondrial cytochrome P-450 and difference spectra induced by deoxycorticosterone and metopirone.
Topics: Adrenal Glands; Argon; Carbon Dioxide; Chemical Phenomena; Chemistry; Cytochromes; Desoxycorticosterone; Metyrapone; Mitochondria; Oxidation-Reduction; Oxidoreductases; Spectrum Analysis | 1969 |
A simplified metyrapone test with determination of plasma ll-deoxycortisol (Metyrapone test with plasma S).
Topics: 17-Hydroxycorticosteroids; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenocortical Hyperfunction; Blood Chemical Analysis; Chemistry, Clinical; Corticosterone; Cortisone; Cushing Syndrome; Desoxycorticosterone; Humans; Hydrocortisone; Hydroxyprogesterones; Hypopituitarism; Methods; Metyrapone; Pituitary Function Tests; Progesterone; Protein Binding; Transcortin; Tritium | 1969 |
The interaction of metopirone with adrenal mitochondrial cytochrome P-450. A mechanism for the inhibition of adrenal steroid 11 beta-hydroxylation.
Topics: Adrenal Glands; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Cytochromes; Desoxycorticosterone; Kinetics; Metyrapone; Mitochondria; Mixed Function Oxygenases; Spectrum Analysis | 1969 |
The presence of two interconvertible forms of 18-hydroxy-11-deoxycorticosterone.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Chemical Phenomena; Chemistry; Chromatography, Paper; Desoxycorticosterone; In Vitro Techniques; Metyrapone; Rats; Subcellular Fractions | 1965 |
Inhibition of the biosynthesis of 18-hydroxy-11-deoxycorticos terone by SU-4885.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Chromatography; Corticosterone; Desoxycorticosterone; Hydroxyprogesterones; In Vitro Techniques; Metyrapone; Progesterone; Rats; Spectrophotometry | 1965 |
Some effects of corticosteroids on tissue histamine levels in the guinea-pig.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Cortisone; Desoxycorticosterone; Dexamethasone; Female; Fludrocortisone; Guinea Pigs; Histamine; Ileum; Lung; Metyrapone | 1965 |
Effects of adrenal steroids and thyroid hormone on creatine and kidney transamidinase in the rat.
Topics: Adrenalectomy; Animals; Corticosterone; Creatine; Desoxycorticosterone; Hydrocortisone; Kidney; Metyrapone; Rats; Transferases; Triiodothyronine | 1966 |
Some factors determining the adrenal response to metyrapone (SU 4885).
Topics: Cushing Syndrome; Desoxycorticosterone; Humans; Hydrocortisone; Metyrapone; Pituitary-Adrenal Function Tests; Tritium; Urine | 1966 |
The effect of infection, hormonal environment, and genetic constitution on the mammary tumor induction in rats by 7,12-dimethylbenz(a)anthracene.
Topics: Animals; Benz(a)Anthracenes; Cell Nucleus; Desoxycorticosterone; Female; Infections; Lung Diseases; Mammary Neoplasms, Experimental; Metyrapone; Progesterone; Rats; Vaginal Smears | 1966 |
Effect of metopiron (SU-4885) on luteinizing hormone and corticosteroid-induced ovulation and spawning in hypophysectomized catfish, Heteropneustes fossilis (bloch).
Topics: Animals; Corticosterone; Desoxycorticosterone; Female; Fishes; Hypophysectomy; Injections, Intraperitoneal; Luteinizing Hormone; Metyrapone; Ovulation; Ovum | 1966 |
The effect of exogenous steroids and steroid inhibitors on IgG transmissions in young rats.
Topics: Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Corticosterone; Cortisone; Desoxycorticosterone; Hydrocortisone; Immunoglobulin G; Intestine, Small; Maternal Deprivation; Metyrapone; Rats; Succinates | 1980 |
Parallelism of 11 beta- and 18-hydroxylation demonstrated by urinary free hormones in man.
Topics: 18-Hydroxydesoxycorticosterone; Adolescent; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Child; Child, Preschool; Corticosterone; Cytochrome P-450 CYP11B2; Desoxycorticosterone; Humans; Hydroxylation; Metyrapone; Reference Values; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases | 1980 |
Two cases of low-renin hypertension thought to be due to excessive secretion of unknown mineralocorticoid.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure; Dehydroepiandrosterone; Desoxycorticosterone; Dexamethasone; Female; Humans; Hydrocortisone; Hypertension; Male; Metyrapone; Mineralocorticoids; Renin | 1982 |
The origin of plasma deoxycorticosterone in the syndrome of congenital adrenal hyperplasia and in acute states of adrenocorticotropin excess.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Child; Cortodoxone; Desoxycorticosterone; Female; Humans; Male; Metabolic Clearance Rate; Metyrapone; Middle Aged; Progesterone | 1983 |
Progesterone C21 hydroxylation and steroid carboxylic acid biosynthesis in the rabbit. In vitro studies with endocrine, metabolic, and potential target tissues.
Topics: Adrenal Glands; Animals; Cytochrome c Group; Desoxycorticosterone; Kidney; Metyrapone; Microsomes; Microsomes, Liver; Progesterone; Rabbits; Steroid 21-Hydroxylase; Steroid Hydroxylases | 1983 |
Mineralocorticoid and metabolic response to metyrapone on normotensive children and children with dexamethasone-suppressible and primary hyperaldosteronism.
Topics: Aldosterone; Child; Desoxycorticosterone; Electrolytes; Female; Humans; Hyperaldosteronism; Hypertension; Male; Metyrapone; Renin | 1981 |
Clinical response to metyrapone as indicated by measurement of mineralocorticoids and glucocorticoids in normal children.
Topics: Adolescent; Aldosterone; Child; Child, Preschool; Corticosterone; Desoxycorticosterone; Humans; Hydrocortisone; Metyrapone; Pituitary-Adrenal System; Radioimmunoassay | 1981 |
Deoxycorticosterone and aldosterone excretion in Cushing's syndrome.
Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Carcinoma; Cushing Syndrome; Desoxycorticosterone; Dexamethasone; Female; Humans; Hydrocortisone; Hyperplasia; Male; Metyrapone; Middle Aged; Pituitary Gland | 1980 |
Steroid production in the thymus: implications for thymocyte selection.
Topics: Aging; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Epithelial Cells; Epithelium; Fetus; Lymphocyte Depletion; Metyrapone; Mice; Mice, Inbred BALB C; Mifepristone; Organ Culture Techniques; Pregnenolone; Receptors, Antigen, T-Cell; Receptors, Glucocorticoid; Signal Transduction; T-Lymphocytes; Thymus Gland | 1994 |
Competition for electron transfer between cytochromes P450scc and P45011 beta in rat adrenal mitochondria.
Topics: Adrenal Cortex; Adrenodoxin; Aminoglutethimide; Animals; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cosyntropin; Desoxycorticosterone; Electron Transport; Female; Ferredoxin-NADP Reductase; Isocitrates; Isoenzymes; Metyrapone; Mitochondria; NADP; Oxidation-Reduction; Pregnenolone; Rats; Rats, Sprague-Dawley; Steroid 11-beta-Hydroxylase; Succinates; Succinic Acid | 1993 |
Aldosterone biosynthesis in the rat brain.
Topics: Aldosterone; Animals; Blotting, Southern; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Corticosterone; Cytochrome P-450 CYP11B2; Desoxycorticosterone; DNA Primers; Enzyme-Linked Immunosorbent Assay; Female; Hydrocortisone; Male; Metyrapone; Mineralocorticoid Receptor Antagonists; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1997 |
Roles of aldosterone and angiotensin in maturation of sodium appetite in furosemide-treated rats.
Topics: Aldosterone; Angiotensin II; Animals; Appetite; Behavior, Animal; Brain; Desoxycorticosterone; Diet, Sodium-Restricted; Diuretics; Eating; Female; Furosemide; Male; Metyrapone; Proto-Oncogene Proteins c-fos; Rats; Sodium Chloride, Dietary | 1999 |
Biosynthesis and metabolism of steroid hormones by human adrenal carcinomas.
Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Bucladesine; Carcinoma; Cell Culture Techniques; Citric Acid Cycle; Desoxycorticosterone; Humans; Metyrapone; Mitochondria; Pregnenolone; Steroid 11-beta-Hydroxylase | 2000 |
Diagnosis of adrenal cortical dysfunction by liquid chromatography-tandem mass spectrometry.
Topics: 17-alpha-Hydroxyprogesterone; Addison Disease; Adrenal Cortex Diseases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Aged; Chromatography, Liquid; Cortisone; Cortodoxone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Male; Mass Spectrometry; Metyrapone; Middle Aged | 2001 |
MECHANISM OF INHIBITION OF ADRENAL STEROID 11BETA-HYDROXYLASE BY METHOPYRAPONE (METOPIRONE).
Topics: Adrenal Cortex Hormones; Adrenal Glands; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Enzyme Inhibitors; Ketones; Metabolism; Metyrapone; Mixed Function Oxygenases; NADP; Pharmacology; Progesterone; Rats; Research; Steroid 11-beta-Hydroxylase | 1963 |
[ACTION OF G-STROPHANTHIN ON WATER AND ELECTROLYTE METABOLISM IN CATS AND THE EFFECT OF ADRENOCORTICAL HORMONES ON THIS ACTION].
Topics: Adrenalectomy; Cats; Desoxycorticosterone; Diuresis; Electrolytes; Ions; Ketones; Metabolism; Metyrapone; Mineralocorticoid Receptor Antagonists; Ouabain; Pharmacology; Potassium; Research; Sodium; Sodium, Dietary; Strophanthins; Urine; Water | 1963 |
[CASE OF PRIMARY HYPERALDOSTERONISM AND THE EFFECT OF VARIOUS DRUGS].
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Benzothiadiazines; Chlorothiazide; Desoxycorticosterone; Diuretics; Electrocardiography; Hyperaldosteronism; Ketones; Metyrapone; Mineralocorticoid Receptor Antagonists; Pathology; Pterins; Radiography, Thoracic; Triamterene | 1964 |
[HYPOPHYSARY COMA IN SHEEHAN'S SYNDROME. ANATOMOCLINICAL STUDY].
Topics: Adrenal Insufficiency; Coma; Desoxycorticosterone; Diagnosis, Differential; Female; Humans; Hydrocortisone; Hypopituitarism; Hypothyroidism; Metyrapone; Mineralocorticoid Receptor Antagonists; Mixed Function Oxygenases; Pathology; Postpartum Hemorrhage; Postpartum Period | 1963 |
AN INHIBITOR OF ADRENAL STEROID 11 BETA-HYDROXYLASE.
Topics: Adrenal Glands; Cortisone; Desoxycorticosterone; Enzyme Inhibitors; Hydroxyprogesterones; Metabolism; Metyrapone; Mineralocorticoid Receptor Antagonists; Mixed Function Oxygenases; Progesterone; Research; Steroid 11-beta-Hydroxylase | 1964 |
HYPOPHYSO-ADRENAL REGULATION OF MOULTING IN THE TOAD.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Anura; Corticosterone; Desoxycorticosterone; Dexamethasone; Estradiol; Growth Hormone; Hydrocortisone; Hypophysectomy; Metyrapone; Molting; Oxytocin; Pharmacology; Physiology; Pituitary Gland; Progesterone; Prolactin; Research; Skin; Thyroxine; Vasopressins | 1964 |
IN VITRO EFFECT OF 2-METHYL-1,2-BIS(3-PYRIDYL)-1-PROPANONE (SU-4885) AND NADPH IN THE MOUSE ADRENAL.
Topics: Adrenal Glands; Animals; Corticosterone; Desoxycorticosterone; In Vitro Techniques; Metabolism; Metyrapone; Mice; Mineralocorticoid Receptor Antagonists; NADP; Oxidation-Reduction; Pharmacology; Progesterone; Research | 1964 |
PHYSIOLOGICAL ACTIVITY AND REGULATION OF THE ANURAN ADRENAL CORTEX (RANA TEMPORARIA L.).
Topics: Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Anura; Corticosterone; Cortisone; Desoxycorticosterone; Histocytochemistry; Hydrocortisone; Hydroxysteroid Dehydrogenases; Ketones; Light; Metyrapone; Periodicity; Pharmacology; Physiology, Comparative; Rana temporaria; Research; Seasons | 1964 |
Indirect role of alpha2-adrenoreceptors in anti-ulcer effect mechanism of nimesulide in rats.
Topics: Adrenalectomy; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; alpha-Methyltyrosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Corticosterone; Desoxycorticosterone; Dose-Response Relationship, Drug; Doxazosin; Epinephrine; Indomethacin; Male; Metyrapone; Prednisolone; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Stomach Ulcer; Sulfonamides; Yohimbine | 2007 |
Taenia crassiceps WFU cysticerci synthesize corticosteroids in vitro: metyrapone regulates the production.
Topics: Animals; Antimetabolites; Chromatography, Thin Layer; Desoxycorticosterone; Metyrapone; Progesterone; Radioimmunoassay; Taenia | 2012 |
A therapeutic combination of metyrapone and oxazepam increases brain levels of GABA-active neurosteroids and decreases cocaine self-administration in male rats.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Desoxycorticosterone; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; GABA Modulators; Male; Metyrapone; Motivation; Oxazepam; Pregnanolone; Rats, Wistar; Self Administration | 2015 |
Physiological and drug-induced changes in blood levels of adrenal steroids and their precursors in cynomolgus monkeys: An application of steroid profiling by LC-MS/MS for evaluation of the adrenal toxicity.
Topics: Adrenal Glands; Aldosterone; Androgens; Animals; Chromatography, Liquid; Circadian Rhythm; Desoxycorticosterone; Female; Humans; Hydrocortisone; Ketoconazole; Macaca fascicularis; Male; Metyrapone; Steroid 11-beta-Hydroxylase; Tandem Mass Spectrometry | 2019 |
Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones.
Topics: Animals; Corticosterone; Desoxycorticosterone; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Humans; Hypothalamo-Hypophyseal System; Male; Metyrapone; Patient Discharge; Pituitary-Adrenal System; Rats; Seizures | 2023 |