desmethylsertraline has been researched along with norfluoxetine in 6 studies
| Studies (desmethylsertraline) | Trials (desmethylsertraline) | Recent Studies (post-2010) (desmethylsertraline) | Studies (norfluoxetine) | Trials (norfluoxetine) | Recent Studies (post-2010) (norfluoxetine) |
|---|---|---|---|---|---|
| 56 | 8 | 9 | 275 | 33 | 69 |
| Protein | Taxonomy | desmethylsertraline (IC50) | norfluoxetine (IC50) |
|---|---|---|---|
| Potassium channel subfamily K member 2 | Homo sapiens (human) | 9 | |
| Sodium channel protein type 1 subunit alpha | Rattus norvegicus (Norway rat) | 0.8 | |
| Potassium voltage-gated channel subfamily C member 1 | Rattus norvegicus (Norway rat) | 0.8 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 2.2909 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dormann, SM; Haefeli, WE; Kerpen, CJ; Ketabi-Kiyanvash, N; Martin-Facklam, M; Weiss, J | 1 |
| Binkley, SN; Ring, BJ; Roskos, L; Wrighton, SA | 1 |
| Court, MH; Duan, SX; Greenblatt, DJ; Hesse, LM; Shader, RI; Venkatakrishnan, K; von Moltke, LL | 1 |
| Banks, KE; Brooks, BW; Chambliss, CK; Johnson, RD; Lewis, RJ; Ramirez, A; Stanley, JK | 1 |
| Lambert, WE; Maudens, KE; Van Peteghem, CH; Wille, SM | 1 |
| Brose, SA; Golovko, MY; Henry, LK; Krout, D; Rodriquez, M; Thompson, BJ | 1 |
6 other study(ies) available for desmethylsertraline and norfluoxetine
| Article | Year |
|---|---|
Inhibition of P-glycoprotein by newer antidepressants.
Topics: Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Endothelium, Vascular; Humans; Reproducibility of Results; Swine; Transfection | 2003 |
Effect of fluoxetine, norfluoxetine, sertraline and desmethyl sertraline on human CYP3A catalyzed 1'-hydroxy midazolam formation in vitro.
Topics: 1-Naphthylamine; Catalysis; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Fluoxetine; Humans; Microsomes, Liver; Midazolam; Mixed Function Oxygenases; Selective Serotonin Reuptake Inhibitors; Sertraline | 1995 |
CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants.
Topics: Antibodies; Antidepressive Agents, Second-Generation; Aryl Hydrocarbon Hydroxylases; Biotransformation; Bupropion; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Fluvoxamine; Humans; Hydroxylation; Isoenzymes; Kinetics; Microsomes, Liver; Oxidoreductases, N-Demethylating; Paroxetine; Piperazines; Sertraline; Triazoles | 2000 |
Determination of select antidepressants in fish from an effluent-dominated stream.
Topics: Animals; Antidepressive Agents; Brain; Fishes; Fluoxetine; Liver; Muscles; Rivers; Selective Serotonin Reuptake Inhibitors; Sertraline; Time Factors; Water Pollutants, Chemical | 2005 |
Development of a solid phase extraction for 13 'new' generation antidepressants and their active metabolites for gas chromatographic-mass spectrometric analysis.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Desvenlafaxine Succinate; Fluoxetine; Gas Chromatography-Mass Spectrometry; Humans; Mianserin; Microchemistry; Mirtazapine; Piperazines; Reproducibility of Results; Sertraline | 2005 |
Inhibition of the Serotonin Transporter Is Altered by Metabolites of Selective Serotonin and Norepinephrine Reuptake Inhibitors and Represents a Caution to Acute or Chronic Treatment Paradigms.
Topics: Animals; Citalopram; Fluoxetine; Mice; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Sertraline; Synaptosomes | 2017 |