desmethylsertraline has been researched along with 1-naphthylamine in 18 studies
| Studies (desmethylsertraline) | Trials (desmethylsertraline) | Recent Studies (post-2010) (desmethylsertraline) | Studies (1-naphthylamine) | Trials (1-naphthylamine) | Recent Studies (post-2010) (1-naphthylamine) |
|---|---|---|---|---|---|
| 56 | 8 | 9 | 1,088 | 137 | 194 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (83.33) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fischette, CT; Reith, ME; Wiener, HL | 1 |
| Fischette, CT; Reith, ME | 1 |
| Kramer, HK; Reith, ME; Wiener, HL | 1 |
| Greenblatt, DJ; Harmatz, JS; Schmider, J; Shader, RI; von Moltke, LL | 1 |
| Audia, JE; Fuller, RW; Hemrick-Luecke, SK; Littlefield, ES | 1 |
| Jenkins, AJ; Levine, B; Smialek, JE | 1 |
| Long, G; Marr, M; Moore, C; Rogowsky, D | 1 |
| Binkley, SN; Ring, BJ; Roskos, L; Wrighton, SA | 1 |
| Clarke, T; Heym, J; Reynolds, L; Rollema, H; Sprouse, J | 1 |
| Ronfeld, RA; Tremaine, LM; Wilner, KD | 1 |
| Foglia, JP; Mammen, OK; Perel, JM; Rudolph, G; Wheeler, SB | 1 |
| Ely, T; Kilts, CD; Landry, JC; Llewellyn, A; Nemeroff, CB; Owens, MJ; Stowe, ZN | 1 |
| Dysken, MW; Hazel, DK; Holden, LA; Vatassery, GT | 1 |
| Blumer, J; Perel, JM; Wisner, KL | 1 |
| Dusci, LJ; Hackett, LP; Ilett, KF; Kristensen, JH; Paech, M; Roberts, MJ; Wojnar-Horton, RE; Yapp, P | 1 |
| Anthony, M; Davis, MF; Fankhauser, M; Freeman, MP; Fried, K; Moreno, F; Nolan, PE; Woosley, RL | 1 |
| Bäckvall, JE; Hoben, C; Paetzold, J; Sortais, JB; Thalén, LK; Zhao, D | 1 |
| Mallett, P; McIntyre, IM | 1 |
2 trial(s) available for desmethylsertraline and 1-naphthylamine
| Article | Year |
|---|---|
Distribution and excretion of sertraline and N-desmethylsertraline in human milk.
Topics: 1-Naphthylamine; Administration, Oral; Adult; Antidepressive Agents; Area Under Curve; Breast Feeding; Chromatography, High Pressure Liquid; Female; Humans; Infant; Male; Milk, Human; Sertraline; Tissue Distribution | 1998 |
Pharmacokinetics of sertraline across pregnancy and postpartum.
Topics: 1-Naphthylamine; Adult; Body Weight; Depressive Disorder, Major; Female; Humans; Longitudinal Studies; Postpartum Period; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Selective Serotonin Reuptake Inhibitors; Sertraline; Young Adult | 2008 |
16 other study(ies) available for desmethylsertraline and 1-naphthylamine
| Article | Year |
|---|---|
Sertraline and cocaine-induced locomotion in mice. I. Acute studies.
Topics: 1-Naphthylamine; Animals; Cocaine; Desipramine; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neurons; Serotonin; Serotonin Antagonists; Sertraline; Sex Factors | 1991 |
Sertraline and cocaine-induced locomotion in mice. II. Chronic studies.
Topics: 1-Naphthylamine; Animals; Body Weight; Cocaine; Female; Mice; Mice, Inbred C57BL; Motor Activity; Serotonin Antagonists; Sertraline | 1991 |
Separation and determination of sertraline and its metabolite, desmethylsertraline, in mouse cerebral cortex by reversed-phase high-performance liquid chromatography.
Topics: 1-Naphthylamine; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Male; Mice; Mice, Inbred C57BL; Naphthalenes; Serotonin Antagonists; Sertraline | 1990 |
N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors.
Topics: 1-Naphthylamine; Amitriptyline; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; Isoenzymes; Ketoconazole; Kinetics; Liver; Mixed Function Oxygenases; Nortriptyline; Quinidine; Selective Serotonin Reuptake Inhibitors; Sertraline | 1995 |
Comparison of desmethylsertraline with sertraline as a monoamine uptake inhibitor in vivo.
Topics: 1-Naphthylamine; Animals; Dose-Response Relationship, Drug; Epinephrine; Hydroxyindoleacetic Acid; Male; Mice; Norepinephrine; Oxidopamine; Selective Serotonin Reuptake Inhibitors; Sertraline | 1995 |
Distribution of sertraline in postmortem cases.
Topics: 1-Naphthylamine; Adult; Aged; Antidepressive Agents; Chromatography, Gas; Female; Humans; Male; Middle Aged; Retrospective Studies; Sertraline; Tissue Distribution | 1994 |
Determination of sertraline and desmethylsertraline in human serum using copolymeric bonded-phase extraction, liquid chromatography and gas chromatography-mass spectrometry.
Topics: 1-Naphthylamine; Antidepressive Agents; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Humans; Sertraline; Spectrophotometry, Ultraviolet | 1994 |
Effect of fluoxetine, norfluoxetine, sertraline and desmethyl sertraline on human CYP3A catalyzed 1'-hydroxy midazolam formation in vitro.
Topics: 1-Naphthylamine; Catalysis; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Fluoxetine; Humans; Microsomes, Liver; Midazolam; Mixed Function Oxygenases; Selective Serotonin Reuptake Inhibitors; Sertraline | 1995 |
Comparison of the effects of sertraline and its metabolite desmethylsertraline on blockade of central 5-HT reuptake in vivo.
Topics: 1-Naphthylamine; Animals; Dose-Response Relationship, Drug; Male; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Sertraline; Time Factors | 1996 |
Pharmacokinetics of sertraline and its N-demethyl metabolite in elderly and young male and female volunteers.
Topics: 1-Naphthylamine; Adult; Age Factors; Aged; Aged, 80 and over; Antidepressive Agents; Area Under Curve; Female; Half-Life; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Sertraline; Sex Factors | 1997 |
Sertraline and norsertraline levels in three breastfed infants.
Topics: 1-Naphthylamine; Breast Feeding; Depressive Disorder; Female; Humans; Infant, Newborn; Puerperal Disorders; Selective Serotonin Reuptake Inhibitors; Sertraline | 1997 |
Sertraline and desmethylsertraline in human breast milk and nursing infants.
Topics: 1-Naphthylamine; Breast Feeding; Depression, Postpartum; Depressive Disorder; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Lactation; Milk, Human; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors; Sertraline | 1997 |
Analysis of sertraline and desmethylsertraline in human plasma and red blood cells.
Topics: 1-Naphthylamine; Antidepressive Agents; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Sertraline | 1997 |
Serum sertraline and N-desmethylsertraline levels in breast-feeding mother-infant pairs.
Topics: 1-Naphthylamine; Breast Feeding; Depressive Disorder; Female; Humans; Infant; Infant, Newborn; Lactation; Male; Selective Serotonin Reuptake Inhibitors; Sertraline | 1998 |
A chemoenzymatic approach to enantiomerically pure amines using dynamic kinetic resolution: application to the synthesis of norsertraline.
Topics: 1-Naphthylamine; Amines; Biocatalysis; Catalysis; Fungal Proteins; Kinetics; Lipase; Organometallic Compounds; Sertraline; Stereoisomerism; Substrate Specificity | 2009 |
Sertraline concentrations and postmortem redistribution.
Topics: 1-Naphthylamine; Analgesics, Opioid; Antidepressive Agents; Central Nervous System Depressants; Chromatography, Gas; Enzyme-Linked Immunosorbent Assay; Ethanol; Flame Ionization; Forensic Toxicology; Gastrointestinal Contents; Humans; Hypnotics and Sedatives; Liver; Selective Serotonin Reuptake Inhibitors; Sertraline | 2012 |