Page last updated: 2024-09-05

desmethylselegiline and rasagiline

desmethylselegiline has been researched along with rasagiline in 2 studies

Compound Research Comparison

Studies (desmethylselegiline)	Trials (desmethylselegiline)	Recent Studies (post-2010) (desmethylselegiline)	Studies (rasagiline)	Trials (rasagiline)	Recent Studies (post-2010) (rasagiline)
42	12	1	535	72	314

Protein Interaction Comparison

Protein	Taxonomy	rasagiline (IC50)
Cholinesterase	Homo sapiens (human)	2.3865
Amine oxidase [flavin-containing] B	Rattus norvegicus (Norway rat)	1.0029
Amine oxidase [flavin-containing] A	Rattus norvegicus (Norway rat)	0.2115
Amine oxidase [flavin-containing] A	Homo sapiens (human)	1.088
Acetylcholinesterase	Homo sapiens (human)	0.019
Amine oxidase [flavin-containing] B	Homo sapiens (human)	0.2217

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chorev, M; Finberg, J; Finkelstein, N; Friedman, R; Goldenberg, W; Goren, T; Gross, A; Herzig, Y; Huang, W; Krais, B; Lavian, G; Lerner, D; Miskolczi, I; Molnar, S; Rantal, F; Razin, M; Sterling, J; Tamas, T; Toth, G; Weinstock, M; Youdim, MB; Zagyva, A; Zekany, A	1
Maruyama, W; Naoi, M	1

Other Studies

2 other study(ies) available for desmethylselegiline and rasagiline

Article	Year
Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease. Journal of medicinal chemistry, 2002, Nov-21, Volume: 45, Issue:24 Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Butyrylcholinesterase; Carbamates; Cattle; Cholinesterase Inhibitors; Humans; Indans; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Phenethylamines; Propylamines; Structure-Activity Relationship	2002
Neuroprotection by (-)-deprenyl and related compounds. Mechanisms of ageing and development, 1999, Volume: 111, Issue:2-3 Topics: Aging; Amphetamines; Animals; Antioxidants; Apoptosis; Cattle; DNA Damage; DNA, Neoplasm; Indans; Monoamine Oxidase Inhibitors; Neuroblastoma; Neuroprotective Agents; Nitrates; Oxidants; Parkinson Disease; Selegiline; Tumor Cells, Cultured	1999

Article

Year

Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease.

Journal of medicinal chemistry, 2002, Nov-21, Volume: 45, Issue:24

Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Butyrylcholinesterase; Carbamates; Cattle; Cholinesterase Inhibitors; Humans; Indans; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Phenethylamines; Propylamines; Structure-Activity Relationship

2002

Neuroprotection by (-)-deprenyl and related compounds.

Mechanisms of ageing and development, 1999, Volume: 111, Issue:2-3

Topics: Aging; Amphetamines; Animals; Antioxidants; Apoptosis; Cattle; DNA Damage; DNA, Neoplasm; Indans; Monoamine Oxidase Inhibitors; Neuroblastoma; Neuroprotective Agents; Nitrates; Oxidants; Parkinson Disease; Selegiline; Tumor Cells, Cultured

1999