Page last updated: 2024-09-03

desmethylmaprotiline and nortriptyline

desmethylmaprotiline has been researched along with nortriptyline in 1 studies

Compound Research Comparison

Studies
(desmethylmaprotiline)
Trials
(desmethylmaprotiline)
Recent Studies (post-2010)
(desmethylmaprotiline)
Studies
(nortriptyline)
Trials
(nortriptyline)
Recent Studies (post-2010) (nortriptyline)
16112,289517327

Protein Interaction Comparison

ProteinTaxonomydesmethylmaprotiline (IC50)nortriptyline (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.016
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.0032
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.347
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.095
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.17
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.027
Alpha-2A adrenergic receptorHomo sapiens (human)0.366
Cytochrome P450 2D26Rattus norvegicus (Norway rat)1.9
Cytochrome P450 2D6Homo sapiens (human)1.95
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.082
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.17
Alpha-2B adrenergic receptorHomo sapiens (human)0.047
Alpha-2C adrenergic receptorHomo sapiens (human)0.1015
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)1.019
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.171
D(1A) dopamine receptorHomo sapiens (human)0.539
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.0032
Histamine H2 receptorHomo sapiens (human)2.334
Alpha-1D adrenergic receptorHomo sapiens (human)0.273
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.051
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.016
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)1.019
5-hydroxytryptamine receptor 1DRattus norvegicus (Norway rat)0.17
5-hydroxytryptamine receptor 1FRattus norvegicus (Norway rat)0.17
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.17
5-hydroxytryptamine receptor 6Rattus norvegicus (Norway rat)0.17
Sodium-dependent serotonin transporterHomo sapiens (human)0.013
5-hydroxytryptamine receptor 7 Rattus norvegicus (Norway rat)0.17
Cytochrome P450 2C19Homo sapiens (human)3
5-hydroxytryptamine receptor 5ARattus norvegicus (Norway rat)0.17
5-hydroxytryptamine receptor 5BRattus norvegicus (Norway rat)0.17
Histamine H1 receptorHomo sapiens (human)0.05
D(3) dopamine receptorHomo sapiens (human)0.179
5-hydroxytryptamine receptor 3ARattus norvegicus (Norway rat)0.17
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.136
Histamine H2 receptorCavia porcellus (domestic guinea pig)7
5-hydroxytryptamine receptor 6Homo sapiens (human)0.554
Voltage-dependent N-type calcium channel subunit alpha-1BHomo sapiens (human)10
Sodium-dependent dopamine transporter Homo sapiens (human)1.678
5-hydroxytryptamine receptor 4 Rattus norvegicus (Norway rat)0.17
5-hydroxytryptamine receptor 3BRattus norvegicus (Norway rat)0.17

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Itoh, M; Nakao, H; Notomi, A; Yufu, N1

Other Studies

1 other study(ies) available for desmethylmaprotiline and nortriptyline

ArticleYear
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
    Folia psychiatrica et neurologica japonica, 1984, Volume: 38, Issue:1

    Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline

1984