desmethylmaprotiline has been researched along with maprotiline in 15 studies
| Studies (desmethylmaprotiline) | Trials (desmethylmaprotiline) | Recent Studies (post-2010) (desmethylmaprotiline) | Studies (maprotiline) | Trials (maprotiline) | Recent Studies (post-2010) (maprotiline) |
|---|---|---|---|---|---|
| 16 | 1 | 1 | 933 | 211 | 59 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (60.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berger, ML; Rebernik, P | 1 |
| Fukuchi, H; Kimura, M; Kimura, Y; Kitaura, T; Miyake, K | 1 |
| Fukuchi, H; Kimura, M; Kimura, Y; Kitaura, T; Miyake, K; Nakahara, T | 1 |
| Hrdina, PD; Lapierre, YD | 1 |
| Baker, GB; Dewhurst, WG; Drebit, R | 1 |
| Baumann, P; Bosshart, P; Gabris, G; Gastpar, M; Koeb, L; Woggon, B | 1 |
| Hasegawa, M; Inoue, M; Kido, H; Kurata, K; Yamaguchi, N | 2 |
| Itoh, M; Nakao, H; Notomi, A; Yufu, N | 1 |
| Iwai, H; Kubo, S; Kuyama, C; Watanabe, S; Yokoyama, S | 1 |
| Jindal, SP; Lutz, T; Vestergaard, P | 1 |
| Richard, A; Sioufi, A | 1 |
| Kuss, HJ; Sirch, S; Zhao, DY | 1 |
| Keller, T; Zollinger, U | 1 |
| Conca, A; Hubmann, MR; König, P; Moll, W; Waschgler, R | 1 |
1 trial(s) available for desmethylmaprotiline and maprotiline
| Article | Year |
|---|---|
Relationship between blood concentrations and clinical effects of a new antidepressant "maprotiline".
Topics: Adult; Anthracenes; Clinical Trials as Topic; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Maprotiline; Middle Aged | 1980 |
14 other study(ies) available for desmethylmaprotiline and maprotiline
| Article | Year |
|---|---|
Differential influence of 7 cations on 16 non-competitive NMDA receptor blockers.
Topics: Animals; Brain; Cations; Diamines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Molecular Structure; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2015 |
Pharmacokinetic analysis of maprotiline and its demethylated metabolite in serum and brain of rats after acute and chronic oral administration of maprotiline.
Topics: Administration, Oral; Animals; Brain; Drug Administration Schedule; Injections, Intravenous; Male; Maprotiline; Mathematical Computing; Models, Biological; Rats; Rats, Sprague-Dawley; Time Factors | 1992 |
Pharmacokinetics of maprotiline and its demethylated metabolite in serum and specific brain regions of rats after acute and chronic administration of maprotiline.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Male; Maprotiline; Rats; Rats, Inbred Strains; Time Factors | 1991 |
Plasma levels of maprotiline and zimelidine and their relationship to clinical response in depressed patients.
Topics: Anthracenes; Chromatography, Gas; Depressive Disorder; Humans; Maprotiline; Psychiatric Status Rating Scales; Zimeldine | 1986 |
Determination of maprotiline and desmethylmaprotiline in plasma and urine by gas chromatography with nitrogen-phosphorus detection.
Topics: Adult; Anthracenes; Chromatography, Gas; Depressive Disorder; Female; Humans; Indicators and Reagents; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales | 1988 |
Acetylation of maprotiline and desmethylmaprotiline in depressive patients phenotyped with sulfamidine, debrisoquine, and mephenytoin.
Topics: Acetylation; Anthracenes; Debrisoquin; Depressive Disorder; Gas Chromatography-Mass Spectrometry; Humans; Maprotiline; Mephenytoin; Phenotype; Sulfamethazine | 1988 |
Serum levels of maprotiline and its adverse effects on depressed patients.
Topics: Adult; Anthracenes; Antidepressive Agents, Tricyclic; Depressive Disorder; Dose-Response Relationship, Drug; Electroencephalography; Female; Humans; Male; Maprotiline; Middle Aged | 1987 |
A comparison of maprotiline and its desmethylated metabolite serum concentrations in outpatients and inpatients.
Topics: Adult; Ambulatory Care; Anthracenes; Depressive Disorder; Dose-Response Relationship, Drug; Female; Hospitalization; Humans; Male; Maprotiline; Middle Aged; Patient Compliance | 1987 |
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline | 1984 |
GLC-mass spectrometric determination of maprotiline and its major metabolite using stable isotope-labeled analog as internal standard.
Topics: Animals; Anthracenes; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Maprotiline; Methods; Rabbits; Reference Standards | 1980 |
Gas chromatographic determination of maprotiline and its N-desmethyl metabolite in human blood using nitrogen detection.
Topics: Anthracenes; Chromatography, Gas; Humans; Maprotiline | 1980 |
Assay for maprotiline in human serum with improved sensitivity and selectivity.
Topics: Half-Life; Humans; Indicators and Reagents; Maprotiline; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Ultrafiltration | 1994 |
Gas chromatographic examination of postmortem specimens after maprotiline intoxication.
Topics: Antidepressive Agents, Second-Generation; Body Fluids; Female; Gas Chromatography-Mass Spectrometry; Humans; Maprotiline; Middle Aged; Poisoning; Suicide | 1997 |
Simultaneous quantification of citalopram, clozapine, fluoxetine, norfluoxetine, maprotiline, desmethylmaprotiline and trazodone in human serum by HPLC analysis.
Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Chromatography, High Pressure Liquid; Citalopram; Clozapine; Fluoxetine; Humans; Maprotiline; Trazodone | 2002 |