Compounds > desmethylastemizole
Page last updated: 2024-09-04

desmethylastemizole and sertindole

desmethylastemizole has been researched along with sertindole in 2 studies

Compound Research Comparison

Studies
(desmethylastemizole)		Trials
(desmethylastemizole)		Recent Studies (post-2010)
(desmethylastemizole)		Studies
(sertindole)		Trials
(sertindole)		Recent Studies (post-2010) (sertindole)
12122763467

Protein Interaction Comparison

ProteinTaxonomydesmethylastemizole (IC50)sertindole (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)8.9
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)7.6
ATP-dependent translocase ABCB1Homo sapiens (human)6.5
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0004
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0004
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0034
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)2
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0034
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0004
Sodium channel protein type 1 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 4 subunit alphaHomo sapiens (human)2.3
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0034
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0041
Sodium channel protein type 7 subunit alphaHomo sapiens (human)2.3
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)7.6
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.0109
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)7.6
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)7.6
Sodium channel protein type 5 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 9 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 2 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 3 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 11 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 8 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 10 subunit alphaHomo sapiens (human)2.3

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keserü, GM1
Jia, L; Sun, H1

Other Studies

2 other study(ies) available for desmethylastemizole and sertindole

ArticleYear
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008