Compounds > desmethylastemizole
Page last updated: 2024-09-04

desmethylastemizole and pimozide

desmethylastemizole has been researched along with pimozide in 3 studies

Compound Research Comparison

Studies
(desmethylastemizole)		Trials
(desmethylastemizole)		Recent Studies (post-2010)
(desmethylastemizole)		Studies
(pimozide)		Trials
(pimozide)		Recent Studies (post-2010) (pimozide)
12121,837143152

Protein Interaction Comparison

ProteinTaxonomydesmethylastemizole (IC50)pimozide (IC50)
XBP1Homo sapiens (human)10
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.201
Ubiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)2
Potassium channel subfamily K member 2Homo sapiens (human)1.8
Bile salt export pumpHomo sapiens (human)10
Sodium channel protein type 2 subunit alphaRattus norvegicus (Norway rat)0.34
ATP-dependent translocase ABCB1Homo sapiens (human)2.2
Cytochrome P450 3A4Homo sapiens (human)9.7
DRattus norvegicus (Norway rat)0.0004
D(3) dopamine receptorRattus norvegicus (Norway rat)0.0004
ATP-dependent translocase ABCB1Mus musculus (house mouse)4.9
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.0004
D(4) dopamine receptorRattus norvegicus (Norway rat)0.0004
Mu-type opioid receptorHomo sapiens (human)0.372
Sodium channel protein type 1 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 4 subunit alphaHomo sapiens (human)0.054
Delta-type opioid receptorHomo sapiens (human)3.76
Kappa-type opioid receptorHomo sapiens (human)0.99
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0004
Sodium channel protein type 7 subunit alphaHomo sapiens (human)0.054
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.201
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.152
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.201
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.201
Sodium channel protein type 5 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 9 subunit alphaHomo sapiens (human)0.054
WD repeat-containing protein 48Homo sapiens (human)2
Sodium channel protein type 2 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 3 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 11 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 8 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 10 subunit alphaHomo sapiens (human)0.054

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keserü, GM1
Bianucci, AM; Calderone, V; Coi, A; Massarelli, I; Testai, L1
Jia, L; Sun, H1

Other Studies

3 other study(ies) available for desmethylastemizole and pimozide

ArticleYear
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:11

    Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG

2008
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008