Page last updated: 2024-09-04

desmethylastemizole and olanzapine

desmethylastemizole has been researched along with olanzapine in 2 studies

Compound Research Comparison

Studies
(desmethylastemizole)
Trials
(desmethylastemizole)
Recent Studies (post-2010)
(desmethylastemizole)
Studies
(olanzapine)
Trials
(olanzapine)
Recent Studies (post-2010) (olanzapine)
12126,3391,3402,383

Protein Interaction Comparison

ProteinTaxonomydesmethylastemizole (IC50)olanzapine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.097
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.155
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.047
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.04
Alpha-2A adrenergic receptorHomo sapiens (human)0.541
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)2.768
D(2) dopamine receptorHomo sapiens (human)0.118
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.047
Alpha-2B adrenergic receptorHomo sapiens (human)0.421
Alpha-2C adrenergic receptorHomo sapiens (human)0.531
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.392
D(1A) dopamine receptorHomo sapiens (human)0.072
D(4) dopamine receptorHomo sapiens (human)0.173
Alpha-1D adrenergic receptorHomo sapiens (human)0.092
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.038
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.021
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.047
Sodium-dependent serotonin transporterHomo sapiens (human)1.033
Histamine H1 receptorHomo sapiens (human)0.013
D(3) dopamine receptorHomo sapiens (human)0.078
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.057
5-hydroxytryptamine receptor 6Homo sapiens (human)0.013
D(2) dopamine receptorRattus norvegicus (Norway rat)0.158
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2028

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keserü, GM1
Jia, L; Sun, H1

Other Studies

2 other study(ies) available for desmethylastemizole and olanzapine

ArticleYear
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008