Page last updated: 2024-09-04

desmethylastemizole and mefloquine hydrochloride

desmethylastemizole has been researched along with mefloquine hydrochloride in 3 studies

Compound Research Comparison

Studies
(desmethylastemizole)
Trials
(desmethylastemizole)
Recent Studies (post-2010)
(desmethylastemizole)
Studies
(mefloquine hydrochloride)
Trials
(mefloquine hydrochloride)
Recent Studies (post-2010) (mefloquine hydrochloride)
1212145138
12121304

Protein Interaction Comparison

ProteinTaxonomydesmethylastemizole (IC50)mefloquine hydrochloride (IC50)
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 24.33
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)5.6234

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keserü, GM1
Chen, X; Chong, CR; Liu, JO; Shi, L; Sullivan, DJ1
Jia, L; Sun, H1

Other Studies

3 other study(ies) available for desmethylastemizole and mefloquine hydrochloride

ArticleYear
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A clinical drug library screen identifies astemizole as an antimalarial agent.
    Nature chemical biology, 2006, Volume: 2, Issue:8

    Topics: Animals; Antimalarials; Astemizole; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance; Drug Resistance, Multiple; Humans; Mice; Plasmodium falciparum; Plasmodium yoelii

2006
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008