Page last updated: 2024-09-04

desmethylastemizole and loratadine

desmethylastemizole has been researched along with loratadine in 2 studies

Compound Research Comparison

Studies
(desmethylastemizole)
Trials
(desmethylastemizole)
Recent Studies (post-2010)
(desmethylastemizole)
Studies
(loratadine)
Trials
(loratadine)
Recent Studies (post-2010) (loratadine)
12121,317462339

Protein Interaction Comparison

ProteinTaxonomydesmethylastemizole (IC50)loratadine (IC50)
Cytochrome P450 2C19Homo sapiens (human)0.016
Histamine H1 receptorHomo sapiens (human)0.23
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.245
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.1717
Bile acid receptorHomo sapiens (human)3.07
Sodium-dependent neutral amino acid transporter B(0)AT2Homo sapiens (human)4

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keserü, GM1
Jia, L; Sun, H1

Other Studies

2 other study(ies) available for desmethylastemizole and loratadine

ArticleYear
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008