desmethylastemizole has been researched along with cyproheptadine in 1 studies
| Studies (desmethylastemizole) | Trials (desmethylastemizole) | Recent Studies (post-2010) (desmethylastemizole) | Studies (cyproheptadine) | Trials (cyproheptadine) | Recent Studies (post-2010) (cyproheptadine) |
|---|---|---|---|---|---|
| 12 | 1 | 2 | 2,297 | 262 | 201 |
| Protein | Taxonomy | desmethylastemizole (IC50) | cyproheptadine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.0024 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.564 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.035 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.016 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0031 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.0038 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.283 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.016 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.164 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0031 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.038 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 1.275 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.122 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.046 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.158 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.564 | |
| Histamine H2 receptor | Homo sapiens (human) | 0.198 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.107 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.001 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.0024 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.122 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0031 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0037 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.048 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0094 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.281 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.14 | |
| Histone-lysine N-methyltransferase SETD7 | Homo sapiens (human) | 2.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janssen, M; Janssen, PA; Janssens, F; Luyckx, M; Stokbroekx, RA; Torremans, J | 1 |
1 other study(ies) available for desmethylastemizole and cyproheptadine
| Article | Year |
|---|---|
New antihistaminic N-heterocyclic 4-piperidinamines. 2. Synthesis and antihistaminic activity of 1-[(4-fluorophenyl)methyl]-N-(4-piperidinyl)-1H-benzimidazol-2-a mines.
Topics: Administration, Oral; Animals; Astemizole; Benzimidazoles; Chemical Phenomena; Chemistry; Guinea Pigs; Histamine; Histamine Antagonists; Male; p-Methoxy-N-methylphenethylamine; Piperidines; Pupil; Rats; Rats, Inbred Strains; Serotonin; Skin Tests; Structure-Activity Relationship | 1985 |