Page last updated: 2024-09-04

desmethylastemizole and alosetron

desmethylastemizole has been researched along with alosetron in 2 studies

Compound Research Comparison

Studies (desmethylastemizole)	Trials (desmethylastemizole)	Recent Studies (post-2010) (desmethylastemizole)	Studies (alosetron)	Trials (alosetron)	Recent Studies (post-2010) (alosetron)
12	1	2	226	37	33

Protein Interaction Comparison

Protein	Taxonomy	alosetron (IC50)
Cytochrome P450 1A2	Homo sapiens (human)	5.3024
Cytochrome P450 3A4	Homo sapiens (human)	0.6
Cytochrome P450 2D6	Homo sapiens (human)	10
Cytochrome P450 2C9	Homo sapiens (human)	10
Cytochrome P450 2B6	Homo sapiens (human)	10
Cytochrome P450 2C19	Homo sapiens (human)	10
5-hydroxytryptamine receptor 2B	Homo sapiens (human)	0.1
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	3.068

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Keserü, GM	1
Jia, L; Sun, H	1

Other Studies

2 other study(ies) available for desmethylastemizole and alosetron

Article	Year
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008

Article

Year

Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.

Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003

Support vector machines classification of hERG liabilities based on atom types.

Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008